$3.29 Billion is the total value of EcoR1 Capital, LLC's 66 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 36.8% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | $697,952,870 | -0.6% | 11,584,280 | 0.0% | 21.24% | +2.5% | |
| SRPT | SAREPTA THERAPEUTICS INC | $388,669,120 | +17.2% | 2,999,453 | 0.0% | 11.83% | +20.9% | |
| APLS | APELLIS PHARMACEUTICALS INC | $268,035,217 | -24.3% | 5,183,431 | 0.0% | 8.16% | -21.9% | |
| ANAB | ANAPTYSBIO INC | $233,076,534 | +21.5% | 7,521,024 | 0.0% | 7.09% | +25.3% | |
| GLPG | Buy | GALAPAGOS NVspon adr | $165,569,797 | +21.4% | 3,730,730 | +16.7% | 5.04% | +25.2% |
| XNCR | XENCOR INC | $137,556,717 | +0.2% | 5,282,516 | 0.0% | 4.19% | +3.4% | |
| ARVN | ARVINAS INC | $106,848,093 | -23.1% | 3,123,300 | 0.0% | 3.25% | -20.7% | |
| RVMD | Buy | REVOLUTION MEDICINES INC | $106,206,972 | +198.9% | 4,458,731 | +147.5% | 3.23% | +208.2% |
| MORF | MORPHIC HLDG INC | $105,704,391 | -5.5% | 3,951,566 | 0.0% | 3.22% | -2.5% | |
| ACAD | ACADIA PHARMACEUTICALS INC | $95,384,346 | -2.7% | 5,991,479 | 0.0% | 2.90% | +0.3% | |
| SWTX | SPRINGWORKS THERAPEUTICS INC | $90,000,010 | -8.8% | 3,460,208 | 0.0% | 2.74% | -6.0% | |
| KURA | KURA ONCOLOGY INC | $82,382,184 | -9.2% | 6,638,371 | 0.0% | 2.51% | -6.3% | |
| ZLAB | Buy | ZAI LAB LTDadr | $66,240,960 | -4.6% | 2,157,686 | +6.3% | 2.02% | -1.6% |
| RLAY | RELAY THERAPEUTICS INC | $62,207,531 | -33.2% | 4,163,824 | 0.0% | 1.89% | -31.1% | |
| New | ZYMEWORKS DEL INC | $59,488,984 | – | 7,568,573 | +100.0% | 1.81% | – | |
| ALEC | ALECTOR INC | $37,441,938 | -2.4% | 4,056,548 | 0.0% | 1.14% | +0.6% | |
| NGM | Buy | NGM BIOPHARMACEUTICALS INC | $32,306,300 | +356.4% | 6,435,518 | +1089.3% | 0.98% | +370.3% |
| ACET | New | ADICET BIO INC | $31,832,658 | – | 3,560,700 | +100.0% | 0.97% | – |
| EWTX | EDGEWISE THERAPEUTICS INC | $31,229,154 | -9.1% | 3,493,194 | 0.0% | 0.95% | -6.4% | |
| TANGO THERAPEUTICS INC | $30,460,252 | +100.3% | 4,201,414 | 0.0% | 0.93% | +106.5% | ||
| AVIR | ATEA PHARMACEUTICALS INC | $29,749,181 | -15.5% | 6,184,861 | 0.0% | 0.90% | -12.9% | |
| VYGR | VOYAGER THERAPEUTICS INC | $28,998,833 | +3.0% | 4,753,907 | 0.0% | 0.88% | +6.3% | |
| ALLO | ALLOGENE THERAPEUTICS INC | $28,230,778 | -41.8% | 4,488,200 | 0.0% | 0.86% | -40.0% | |
| DYN | New | DYNE THERAPEUTICS INC | $26,916,431 | – | 2,322,384 | +100.0% | 0.82% | – |
| NUVB | NUVATION BIO INC | $26,681,363 | -14.3% | 13,896,543 | 0.0% | 0.81% | -11.6% | |
| CRNX | CRINETICS PHARMACEUTICALS IN | $24,343,813 | -6.8% | 1,330,263 | 0.0% | 0.74% | -3.9% | |
| ORIC | ORIC PHARMACEUTICALS INC | $20,132,421 | +84.1% | 3,418,068 | 0.0% | 0.61% | +89.8% | |
| KYMR | KYMERA THERAPEUTICS INC | $19,870,481 | +14.7% | 796,093 | 0.0% | 0.60% | +18.2% | |
| GRPH | Buy | GRAPHITE BIO INC | $18,964,159 | +278.1% | 5,712,096 | +261.0% | 0.58% | +289.9% |
| JANX | JANUX THERAPEUTICS INC | $18,718,771 | -2.7% | 1,421,319 | 0.0% | 0.57% | +0.4% | |
| KDNY | CHINOOK THERAPEUTICS INC | $18,078,000 | +33.3% | 690,000 | 0.0% | 0.55% | +37.5% | |
| CNTA | Buy | CENTESSA PHARMACEUTICALS PLCsponsored ads | $16,220,065 | +24.7% | 5,232,279 | +61.7% | 0.49% | +28.6% |
| PSTX | POSEIDA THERAPEUTICS INC | $14,045,000 | +50.1% | 2,650,000 | 0.0% | 0.43% | +54.7% | |
| VENTYX BIOSCIENCES INC | $13,116,000 | -6.1% | 400,000 | 0.0% | 0.40% | -3.2% | ||
| OVID | OVID THERAPEUTICS INC | $11,378,364 | +1.1% | 6,117,400 | 0.0% | 0.35% | +4.2% | |
| New | PRIME MEDICINE INC | $11,148,000 | – | 600,000 | +100.0% | 0.34% | – | |
| CGEM | Sell | CULLINAN ONCOLOGY INC | $10,919,651 | -25.5% | 1,035,038 | -9.5% | 0.33% | -23.3% |
| Sell | 2SEVENTY BIO INC | $10,714,539 | -68.5% | 1,143,494 | -51.2% | 0.33% | -67.6% | |
| GERN | Buy | GERON CORP | $9,748,987 | +81.0% | 4,028,507 | +75.0% | 0.30% | +86.8% |
| AVEO | AVEO PHARMACEUTICALS INC | $9,724,811 | +81.6% | 650,489 | 0.0% | 0.30% | +87.3% | |
| BCAB | New | BIOATLA INC | $9,276,622 | – | 1,124,439 | +100.0% | 0.28% | – |
| DSGN | Sell | DESIGN THERAPEUTICS INC | $9,079,105 | -78.4% | 884,903 | -64.9% | 0.28% | -77.8% |
| GRCL | Buy | GRACELL BIOTECHNOLOGIES INCsponsored ads | $7,689,365 | +24.3% | 3,343,202 | +74.0% | 0.23% | +27.9% |
| MGNX | Buy | MACROGENICS INC | $7,498,123 | +132.8% | 1,117,455 | +20.0% | 0.23% | +140.0% |
| IMTX | New | IMMATICS N.V | $6,471,530 | – | 743,000 | +100.0% | 0.20% | – |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | $6,146,766 | -22.6% | 415,322 | 0.0% | 0.19% | -20.1% | |
| DTIL | PRECISION BIOSCIENCES INC | $5,992,805 | -8.5% | 5,035,971 | 0.0% | 0.18% | -5.7% | |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $3,992,000 | +0.8% | 400,000 | 0.0% | 0.12% | +3.4% | |
| SELB | SELECTA BIOSCIENCES INC | $3,955,000 | -31.1% | 3,500,000 | 0.0% | 0.12% | -29.0% | |
| ALGS | ALIGOS THERAPEUTICS INC | $3,762,392 | -13.4% | 3,948,360 | 0.0% | 0.12% | -10.2% | |
| PRAX | Buy | PRAXIS PRECISION MEDICINES I | $3,773,071 | +11.1% | 1,585,324 | +5.9% | 0.12% | +15.0% |
| New | ABEONA THERAPEUTICS INC | $3,347,824 | – | 1,086,956 | +100.0% | 0.10% | – | |
| SURF | SURFACE ONCOLOGY INC | $3,218,265 | -21.2% | 3,924,713 | 0.0% | 0.10% | -18.3% | |
| ERASCA INC | $2,924,081 | -44.7% | 678,441 | 0.0% | 0.09% | -42.9% | ||
| HOOK | Sell | HOOKIPA PHARMA INC | $2,003,526 | -70.1% | 2,473,489 | -50.5% | 0.06% | -69.2% |
| EUCR | EUCRATES BIOMEDICAL ACQU COR | $1,998,000 | -0.3% | 200,000 | 0.0% | 0.06% | +3.4% | |
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $1,849,599 | -14.3% | 963,333 | 0.0% | 0.06% | -12.5% | |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $1,515,000 | +1.9% | 150,000 | 0.0% | 0.05% | +4.5% | |
| TPST | TEMPEST THERAPEUTICS INC | $1,185,958 | -33.9% | 1,031,268 | 0.0% | 0.04% | -32.1% | |
| ITOS | ITEOS THERAPEUTICS INC | $790,574 | +2.5% | 40,480 | 0.0% | 0.02% | +4.3% | |
| New | NEWAMSTERDAM PHARMA COMPANY*w exp 11/22/202 added | $726,649 | – | 66,665 | +100.0% | 0.02% | – | |
| EUCRW | EUCRATES BIOMEDICAL ACQU COR*w exp 10/23/202 | $665,993 | -0.3% | 66,666 | 0.0% | 0.02% | 0.0% | |
| KRON | KRONOS BIO INC | $529,384 | -51.7% | 326,780 | 0.0% | 0.02% | -50.0% | |
| BDTX | New | BLACK DIAMOND THERAPEUTICS I | $507,836 | – | 282,131 | +100.0% | 0.02% | – |
| CMAXW | CAREMAX INC*w exp 06/08/202 | $365,000 | -48.5% | 100,000 | 0.0% | 0.01% | -47.6% | |
| SURROZEN INC*w exp 08/01/203 | $38,792 | -71.3% | 66,665 | 0.0% | 0.00% | -75.0% | ||
| TMPMW | Exit | TURMERIC ACQUISITION CORP*w exp 10/08/202 | $0 | – | -33,333 | -100.0% | -0.01% | – |
| OMEG | Exit | OMEGA ALPHA SPACcl a | $0 | – | -50,000 | -100.0% | -0.02% | – |
| FLACW | Exit | FRAZIER LIFESCIENCES ACQU CO*w exp 11/30/202 | $0 | – | -66,665 | -100.0% | -0.02% | – |
| Exit | NUVALENT INC | $0 | – | -40,970 | -100.0% | -0.02% | – | |
| RETA | Exit | REATA PHARMACEUTICALS INCcl a | $0 | – | -38,467 | -100.0% | -0.03% | – |
| TMPM | Exit | TURMERIC ACQUISITION CORPcl a | $0 | – | -100,000 | -100.0% | -0.03% | – |
| DSGN | Exit | DESIGN THERAPEUTICS INCcall | $0 | – | -63,400 | -100.0% | -0.03% | – |
| BLSA | Exit | BCLS ACQUISITION CORP | $0 | – | -200,000 | -100.0% | -0.06% | – |
| FVAM | Exit | 5 01 ACQUISITION CORP | $0 | – | -200,000 | -100.0% | -0.06% | – |
| KNTE | Exit | KINNATE BIOPHARMA INC | $0 | – | -175,000 | -100.0% | -0.06% | – |
| ASND | Exit | ASCENDIS PHARMA A/Ssponsored adr | $0 | – | -27,208 | -100.0% | -0.08% | – |
| FLAC | Exit | FRAZIER LIFESCIENCES ACQU CO | $0 | – | -487,615 | -100.0% | -0.14% | – |
| JYAC | Exit | JIYA ACQUISITION CORP | $0 | – | -500,000 | -100.0% | -0.15% | – |
| ARGX | Exit | ARGENX SEsponsored adr | $0 | – | -17,527 | -100.0% | -0.18% | – |
| AKUS | Exit | AKOUOS INC | $0 | – | -1,975,984 | -100.0% | -0.39% | – |
| SGEN | Exit | SEAGEN INC | $0 | – | -285,793 | -100.0% | -1.15% | – |
| RNA | Exit | AVIDITY BIOSCIENCES INC | $0 | – | -2,899,285 | -100.0% | -1.40% | – |
| GOSS | Exit | GOSSAMER BIO INC | $0 | – | -4,160,887 | -100.0% | -1.47% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -1,015,572 | -100.0% | -2.09% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.