$3.39 Billion is the total value of EcoR1 Capital, LLC's 76 reported holdings in Q3 2022. The portfolio turnover from Q2 2022 to Q3 2022 was 27.5% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | $702,355,000 | +123.3% | 11,584,280 | 0.0% | 20.73% | +91.0% | |
| APLS | APELLIS PHARMACEUTICALS INC | $354,028,000 | +51.0% | 5,183,431 | 0.0% | 10.45% | +29.1% | |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $331,560,000 | +54.2% | 2,999,453 | +4.6% | 9.79% | +31.9% |
| ANAB | ANAPTYSBIO INC | $191,861,000 | +25.7% | 7,521,024 | 0.0% | 5.66% | +7.5% | |
| ARVN | ARVINAS INC | $138,956,000 | +5.7% | 3,123,300 | 0.0% | 4.10% | -9.6% | |
| XNCR | Buy | XENCOR INC | $137,240,000 | -5.1% | 5,282,516 | +0.0% | 4.05% | -18.8% |
| GLPG | GALAPAGOS NVspon adr | $136,341,000 | -23.6% | 3,197,500 | 0.0% | 4.02% | -34.7% | |
| MORF | MORPHIC HLDG INC | $111,829,000 | +30.4% | 3,951,566 | 0.0% | 3.30% | +11.5% | |
| SWTX | New | SPRINGWORKS THERAPEUTICS INC | $98,720,000 | – | 3,460,208 | +100.0% | 2.91% | – |
| ACAD | ACADIA PHARMACEUTICALS INC | $98,021,000 | +16.1% | 5,991,479 | 0.0% | 2.89% | -0.7% | |
| RLAY | Buy | RELAY THERAPEUTICS INC | $93,145,000 | +49.3% | 4,163,824 | +11.8% | 2.75% | +27.7% |
| KURA | KURA ONCOLOGY INC | $90,680,000 | -25.5% | 6,638,371 | 0.0% | 2.68% | -36.3% | |
| MRTX | New | MIRATI THERAPEUTICS INC | $70,928,000 | – | 1,015,572 | +100.0% | 2.09% | – |
| ZLAB | Sell | ZAI LAB LTDadr | $69,435,000 | -17.7% | 2,030,252 | -16.5% | 2.05% | -29.6% |
| GOSS | New | GOSSAMER BIO INC | $49,847,000 | – | 4,160,887 | +100.0% | 1.47% | – |
| ALLO | ALLOGENE THERAPEUTICS INC | $48,473,000 | -5.3% | 4,488,200 | 0.0% | 1.43% | -19.0% | |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $47,345,000 | +18.1% | 2,899,285 | +5.1% | 1.40% | +0.9% |
| DSGN | Sell | DESIGN THERAPEUTICS INC | $42,122,000 | +14.2% | 2,519,268 | -4.4% | 1.24% | -2.4% |
| SGEN | Sell | SEAGEN INC | $39,105,000 | -78.1% | 285,793 | -71.7% | 1.15% | -81.3% |
| ALEC | ALECTOR INC | $38,375,000 | -6.9% | 4,056,548 | 0.0% | 1.13% | -20.4% | |
| RVMD | Sell | REVOLUTION MEDICINES INC | $35,532,000 | -57.4% | 1,801,847 | -57.9% | 1.05% | -63.6% |
| AVIR | Sell | ATEA PHARMACEUTICALS INC | $35,192,000 | -21.8% | 6,184,861 | -2.5% | 1.04% | -33.1% |
| EWTX | Buy | EDGEWISE THERAPEUTICS INC | $34,373,000 | +83.0% | 3,493,194 | +48.0% | 1.02% | +56.6% |
| Sell | 2SEVENTY BIO INC | $34,066,000 | -26.2% | 2,341,313 | -33.0% | 1.00% | -36.9% | |
| NUVB | NUVATION BIO INC | $31,128,000 | -30.9% | 13,896,543 | 0.0% | 0.92% | -40.9% | |
| VYGR | VOYAGER THERAPEUTICS INC | $28,143,000 | +0.2% | 4,753,907 | 0.0% | 0.83% | -14.3% | |
| CRNX | CRINETICS PHARMACEUTICALS IN | $26,126,000 | +5.3% | 1,330,263 | 0.0% | 0.77% | -9.9% | |
| JANX | JANUX THERAPEUTICS INC | $19,245,000 | +10.9% | 1,421,319 | 0.0% | 0.57% | -5.2% | |
| KYMR | New | KYMERA THERAPEUTICS INC | $17,331,000 | – | 796,093 | +100.0% | 0.51% | – |
| Buy | TANGO THERAPEUTICS INC | $15,209,000 | +45.8% | 4,201,414 | +82.5% | 0.45% | +24.7% | |
| CGEM | Sell | CULLINAN ONCOLOGY INC | $14,656,000 | -2.3% | 1,143,218 | -2.3% | 0.43% | -16.4% |
| Sell | VENTYX BIOSCIENCES INC | $13,964,000 | -12.2% | 400,000 | -69.2% | 0.41% | -25.0% | |
| KDNY | CHINOOK THERAPEUTICS INC | $13,565,000 | +12.4% | 690,000 | 0.0% | 0.40% | -4.1% | |
| AKUS | AKOUOS INC | $13,358,000 | +44.1% | 1,975,984 | 0.0% | 0.39% | +23.1% | |
| CNTA | Buy | CENTESSA PHARMACEUTICALS PLCsponsored ads | $13,010,000 | +813.6% | 3,236,352 | +1007.1% | 0.38% | +683.7% |
| OVID | OVID THERAPEUTICS INC | $11,256,000 | -14.4% | 6,117,400 | 0.0% | 0.33% | -26.9% | |
| ORIC | ORIC PHARMACEUTICALS INC | $10,938,000 | -28.6% | 3,418,068 | 0.0% | 0.32% | -38.9% | |
| PSTX | New | POSEIDA THERAPEUTICS INC | $9,355,000 | – | 2,650,000 | +100.0% | 0.28% | – |
| ARQT | Sell | ARCUTIS BIOTHERAPEUTICS INC | $7,937,000 | -58.4% | 415,322 | -53.6% | 0.23% | -64.5% |
| NGM | NGM BIOPHARMACEUTICALS INC | $7,078,000 | +2.0% | 541,108 | 0.0% | 0.21% | -12.6% | |
| HOOK | HOOKIPA PHARMA INC | $6,700,000 | -17.8% | 5,000,000 | 0.0% | 0.20% | -29.5% | |
| DTIL | PRECISION BIOSCIENCES INC | $6,547,000 | -18.8% | 5,035,971 | 0.0% | 0.19% | -30.6% | |
| GRCL | GRACELL BIOTECHNOLOGIES INCsponsored ads | $6,187,000 | -41.4% | 1,921,310 | 0.0% | 0.18% | -49.9% | |
| ARGX | Sell | ARGENX SEsponsored adr | $6,188,000 | -86.9% | 17,527 | -86.0% | 0.18% | -88.8% |
| SELB | SELECTA BIOSCIENCES INC | $5,740,000 | +25.2% | 3,500,000 | 0.0% | 0.17% | +7.0% | |
| GERN | Sell | GERON CORP | $5,387,000 | -75.5% | 2,301,980 | -83.8% | 0.16% | -79.0% |
| AVEO | Buy | AVEO PHARMACEUTICALS INC | $5,354,000 | +26.0% | 650,489 | +0.5% | 0.16% | +7.5% |
| ERASCA INC | $5,292,000 | +40.0% | 678,441 | 0.0% | 0.16% | +20.0% | ||
| GRPH | Buy | GRAPHITE BIO INC | $5,015,000 | +56.9% | 1,582,135 | +36.1% | 0.15% | +34.5% |
| JYAC | JIYA ACQUISITION CORP | $4,985,000 | +0.9% | 500,000 | 0.0% | 0.15% | -14.0% | |
| FLAC | Sell | FRAZIER LIFESCIENCES ACQU CO | $4,862,000 | -16.2% | 487,615 | -17.0% | 0.14% | -28.0% |
| ALGS | ALIGOS THERAPEUTICS INC | $4,343,000 | -9.1% | 3,948,360 | 0.0% | 0.13% | -22.4% | |
| SURF | Sell | SURFACE ONCOLOGY INC | $4,082,000 | -46.5% | 3,924,713 | -15.7% | 0.12% | -54.4% |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $3,960,000 | -0.6% | 400,000 | 0.0% | 0.12% | -15.2% | |
| PRAX | Buy | PRAXIS PRECISION MEDICINES I | $3,397,000 | +559.6% | 1,496,324 | +612.2% | 0.10% | +455.6% |
| MGNX | New | MACROGENICS INC | $3,221,000 | – | 930,955 | +100.0% | 0.10% | – |
| ASND | New | ASCENDIS PHARMA A/Ssponsored adr | $2,809,000 | – | 27,208 | +100.0% | 0.08% | – |
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $2,158,000 | -30.9% | 963,333 | 0.0% | 0.06% | -40.7% | |
| KNTE | KINNATE BIOPHARMA INC | $2,091,000 | -5.3% | 175,000 | 0.0% | 0.06% | -18.4% | |
| BLSA | BCLS ACQUISITION CORP | $2,004,000 | +1.2% | 200,000 | 0.0% | 0.06% | -13.2% | |
| FVAM | 5 01 ACQUISITION CORP | $2,000,000 | +1.0% | 200,000 | 0.0% | 0.06% | -13.2% | |
| EUCR | EUCRATES BIOMEDICAL ACQU COR | $2,004,000 | +1.2% | 200,000 | 0.0% | 0.06% | -13.2% | |
| TPST | TEMPEST THERAPEUTICS INC | $1,794,000 | -19.1% | 1,031,268 | 0.0% | 0.05% | -31.2% | |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $1,487,000 | +1.0% | 150,000 | 0.0% | 0.04% | -13.7% | |
| KRON | KRONOS BIO INC | $1,095,000 | -7.9% | 326,780 | 0.0% | 0.03% | -22.0% | |
| DSGN | New | DESIGN THERAPEUTICS INCcall | $1,060,000 | – | 63,400 | +100.0% | 0.03% | – |
| TMPM | TURMERIC ACQUISITION CORPcl a | $1,000,000 | +0.7% | 100,000 | 0.0% | 0.03% | -11.8% | |
| RETA | Sell | REATA PHARMACEUTICALS INCcl a | $967,000 | -98.4% | 38,467 | -98.1% | 0.03% | -98.6% |
| ITOS | Sell | ITEOS THERAPEUTICS INC | $771,000 | -86.6% | 40,480 | -85.5% | 0.02% | -88.4% |
| New | NUVALENT INC | $796,000 | – | 40,970 | +100.0% | 0.02% | – | |
| CMAXW | CAREMAX INC*w exp 06/08/202 | $709,000 | +95.3% | 100,000 | 0.0% | 0.02% | +61.5% | |
| EUCRW | EUCRATES BIOMEDICAL ACQU COR*w exp 10/23/202 | $668,000 | +1.2% | 66,666 | 0.0% | 0.02% | -13.0% | |
| FLACW | FRAZIER LIFESCIENCES ACQU CO*w exp 11/30/202 | $665,000 | +1.1% | 66,665 | 0.0% | 0.02% | -13.0% | |
| OMEG | OMEGA ALPHA SPACcl a | $497,000 | +0.8% | 50,000 | 0.0% | 0.02% | -11.8% | |
| TMPMW | TURMERIC ACQUISITION CORP*w exp 10/08/202 | $333,000 | +0.6% | 33,333 | 0.0% | 0.01% | -9.1% | |
| SURROZEN INC*w exp 08/01/203 | $135,000 | -32.5% | 66,665 | 0.0% | 0.00% | -42.9% | ||
| BOLT | Exit | BOLT BIOTHERAPEUTICS INC | $0 | – | -150,000 | -100.0% | -0.01% | – |
| EVLO | Exit | EVELO BIOSCIENCES INC | $0 | – | -200,417 | -100.0% | -0.02% | – |
| Exit | PARDES BIOSCIENCES INC | $0 | – | -200,000 | -100.0% | -0.02% | – | |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -1,046,700 | -100.0% | -0.04% | – |
| MRSN | Exit | MERSANA THERAPEUTICS INC | $0 | – | -310,960 | -100.0% | -0.05% | – |
| OLMA | Exit | OLEMA PHARMACEUTICALS INC | $0 | – | -353,701 | -100.0% | -0.05% | – |
| DYN | Exit | DYNE THERAPEUTICS INC | $0 | – | -215,000 | -100.0% | -0.05% | – |
| VERV | Exit | VERVE THERAPEUTICS INC | $0 | – | -98,593 | -100.0% | -0.05% | – |
| SBTX | Exit | SILVERBACK THERAPEUTICS INC | $0 | – | -575,359 | -100.0% | -0.08% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEWput | $0 | – | -115,200 | -100.0% | -0.11% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -182,783 | -100.0% | -0.48% | – |
| EXEL | Exit | EXELIXIS INCcall | $0 | – | -760,000 | -100.0% | -0.55% | – |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -1,646,260 | -100.0% | -1.50% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.