$2.96 Billion is the total value of EcoR1 Capital, LLC's 51 reported holdings in Q3 2023. The portfolio turnover from Q2 2023 to Q3 2023 was 37.7% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | $558,941,510 | -29.3% | 11,584,280 | 0.0% | 18.85% | -2.7% | |
| APLS | Buy | APELLIS PHARMACEUTICALS INC | $414,630,636 | -16.5% | 10,899,859 | +99.9% | 13.99% | +14.9% |
| MRTX | New | MIRATI THERAPEUTICS INC | $250,400,260 | – | 5,748,399 | +100.0% | 8.45% | – |
| GLPG | GALAPAGOS NVspon adr | $198,879,059 | -15.0% | 5,756,268 | 0.0% | 6.71% | +17.0% | |
| RVMD | Sell | REVOLUTION MEDICINES INC | $154,395,248 | -19.8% | 5,577,863 | -22.5% | 5.21% | +10.4% |
| ANAB | ANAPTYSBIO INC | $135,077,591 | -11.7% | 7,521,024 | 0.0% | 4.56% | +21.6% | |
| ACAD | ACADIA PHARMACEUTICALS INC | $124,862,422 | -13.0% | 5,991,479 | 0.0% | 4.21% | +19.8% | |
| ARVN | Buy | ARVINAS INC | $107,373,117 | +7.7% | 5,467,063 | +36.1% | 3.62% | +48.3% |
| XNCR | XENCOR INC | $106,442,697 | -19.3% | 5,282,516 | 0.0% | 3.59% | +11.1% | |
| Buy | TANGO THERAPEUTICS INC | $98,205,621 | +630.9% | 8,721,636 | +115.5% | 3.31% | +907.0% | |
| ZYMEWORKS INC | $85,193,579 | -26.6% | 13,437,473 | 0.0% | 2.87% | +1.0% | ||
| SWTX | SPRINGWORKS THERAPEUTICS INC | $80,000,009 | -11.8% | 3,460,208 | 0.0% | 2.70% | +21.4% | |
| KURA | KURA ONCOLOGY INC | $52,958,664 | -13.8% | 5,806,871 | 0.0% | 1.79% | +18.7% | |
| JAZZ | JAZZ PHARMACEUTICALS PLC | $47,687,120 | +4.4% | 368,411 | 0.0% | 1.61% | +43.7% | |
| CRNX | Buy | CRINETICS PHARMACEUTICALS IN | $45,510,022 | +89.9% | 1,530,263 | +15.0% | 1.54% | +161.5% |
| CNTA | CENTESSA PHARMACEUTICALS PLCsponsored ads | $36,353,500 | +4.5% | 5,618,779 | 0.0% | 1.23% | +43.9% | |
| RLAY | RELAY THERAPEUTICS INC | $35,017,760 | -33.0% | 4,163,824 | 0.0% | 1.18% | -7.8% | |
| MORF | Sell | MORPHIC HLDG INC | $33,911,153 | -84.6% | 1,480,190 | -61.5% | 1.14% | -78.8% |
| VYGR | VOYAGER THERAPEUTICS INC | $29,849,179 | -32.3% | 3,851,507 | 0.0% | 1.01% | -6.8% | |
| New | NEUMORA THERAPEUTICS INC. | $29,228,160 | – | 2,071,450 | +100.0% | 0.99% | – | |
| APLS | New | APELLIS PHARMACEUTICALS INCcall | $27,864,300 | – | 732,500 | +100.0% | 0.94% | – |
| ALEC | ALECTOR INC | $26,286,431 | +7.8% | 4,056,548 | 0.0% | 0.89% | +48.6% | |
| NUVB | Buy | NUVATION BIO INC | $25,740,922 | +2.9% | 19,209,643 | +38.2% | 0.87% | +41.6% |
| MRSN | New | MERSANA THERAPEUTICS INC | $24,593,154 | – | 19,364,688 | +100.0% | 0.83% | – |
| OVID | OVID THERAPEUTICS INC | $23,490,816 | +17.1% | 6,117,400 | 0.0% | 0.79% | +61.0% | |
| GRPH | GRAPHITE BIO INC | $21,175,346 | -4.6% | 8,538,446 | 0.0% | 0.71% | +31.2% | |
| AVIR | ATEA PHARMACEUTICALS INC | $20,987,583 | -19.8% | 6,995,861 | 0.0% | 0.71% | +10.5% | |
| ORIC | ORIC PHARMACEUTICALS INC | $20,679,311 | -22.0% | 3,418,068 | 0.0% | 0.70% | +7.4% | |
| EWTX | EDGEWISE THERAPEUTICS INC | $20,016,002 | -26.1% | 3,493,194 | 0.0% | 0.68% | +1.8% | |
| Buy | THIRD HARMONIC BIO INC | $19,057,817 | +89.7% | 2,982,444 | +42.8% | 0.64% | +161.4% | |
| New | ACELYRIN INC | $14,260,384 | – | 1,402,201 | +100.0% | 0.48% | – | |
| ALLO | ALLOGENE THERAPEUTICS INC | $14,227,594 | -36.2% | 4,488,200 | 0.0% | 0.48% | -12.2% | |
| TSCAN THERAPEUTICS INC | $12,800,000 | +2.4% | 5,000,000 | 0.0% | 0.43% | +41.2% | ||
| DCPH | New | DECIPHERA PHARMACEUTICALS IN | $12,630,960 | – | 993,000 | +100.0% | 0.43% | – |
| GBIO | GENERATION BIO CO | $7,757,626 | -31.1% | 2,046,867 | 0.0% | 0.26% | -5.1% | |
| GOSS | New | GOSSAMER BIO INC | $7,657,932 | – | 9,195,404 | +100.0% | 0.26% | – |
| PHAT | PHATHOM PHARMACEUTICALS INC | $7,259,000 | -27.6% | 700,000 | 0.0% | 0.24% | -0.4% | |
| NGM | NGM BIOPHARMACEUTICALS INC | $6,886,004 | -58.7% | 6,435,518 | 0.0% | 0.23% | -43.1% | |
| PRIME MEDICINE INC | $5,724,000 | -34.9% | 600,000 | 0.0% | 0.19% | -10.2% | ||
| PRQR | PROQR THRAPEUTICS N V | $3,874,021 | -19.8% | 2,980,016 | 0.0% | 0.13% | +11.0% | |
| PRLD | PRELUDE THERAPEUTICS INC | $3,576,527 | -31.3% | 1,157,452 | 0.0% | 0.12% | -5.5% | |
| ALGS | ALIGOS THERAPEUTICS INC | $2,949,425 | -23.1% | 3,948,360 | 0.0% | 0.10% | +5.3% | |
| HOOK | HOOKIPA PHARMA INC | $2,830,535 | -30.0% | 4,595,024 | 0.0% | 0.10% | -4.0% | |
| New | AEGLEA BIOTHERAPEUTICS INC | $2,449,951 | – | 199,996 | +100.0% | 0.08% | – | |
| ALLK | ALLAKOS INC | $1,700,003 | -47.9% | 748,900 | 0.0% | 0.06% | -28.8% | |
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $1,290,866 | -25.6% | 963,333 | 0.0% | 0.04% | +4.8% | |
| RVMD | New | REVOLUTION MEDICINES INCcall | $866,384 | – | 31,300 | +100.0% | 0.03% | – |
| NEWAMSTERDAM PHARMA COMPANY*w exp 11/22/202 | $616,651 | -22.2% | 66,665 | 0.0% | 0.02% | +10.5% | ||
| TPST | Sell | TEMPEST THERAPEUTICS INC | $283,676 | -80.1% | 931,000 | -17.1% | 0.01% | -71.4% |
| CMAXW | CAREMAX INC*w exp 06/08/202 | $212,000 | -31.8% | 100,000 | 0.0% | 0.01% | -12.5% | |
| SURROZEN INC*w exp 08/01/203 | $32,666 | -10.9% | 66,665 | 0.0% | 0.00% | 0.0% | ||
| KRON | Exit | KRONOS BIO INC | $0 | – | -326,780 | -100.0% | -0.01% | – |
| PSTX | Exit | POSEIDA THERAPEUTICS INC | $0 | – | -676,296 | -100.0% | -0.03% | – |
| FDMT | Exit | 4D MOLECULAR THERAPEUTICS IN | $0 | – | -66,978 | -100.0% | -0.03% | – |
| AGLE | Exit | AEGLEA BIOTHERAPEUTICS INC | $0 | – | -5,000,000 | -100.0% | -0.06% | – |
| KURA | Exit | KURA ONCOLOGY INCcall | $0 | – | -500,000 | -100.0% | -0.13% | – |
| JANX | Exit | JANUX THERAPEUTICS INC | $0 | – | -452,590 | -100.0% | -0.13% | – |
| ZNTL | Exit | ZENTALIS PHARMACEUTICALS INC | $0 | – | -300,000 | -100.0% | -0.21% | – |
| DYN | Exit | DYNE THERAPEUTICS INC | $0 | – | -798,701 | -100.0% | -0.22% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -1,798,300 | -100.0% | -2.78% | – |
| JNJ | Exit | JOHNSON & JOHNSONcall | $0 | – | -1,700,000 | -100.0% | -6.89% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -3,660,798 | -100.0% | -10.27% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.