$3.11 Billion is the total value of EcoR1 Capital, LLC's 58 reported holdings in Q1 2023. The portfolio turnover from Q4 2022 to Q1 2023 was 27.3% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | $561,490,052 | -19.6% | 11,584,280 | 0.0% | 18.08% | -14.9% | |
| SRPT | SAREPTA THERAPEUTICS INC | $413,414,607 | +6.4% | 2,999,453 | 0.0% | 13.31% | +12.5% | |
| APLS | Buy | APELLIS PHARMACEUTICALS INC | $359,590,636 | +34.2% | 5,451,647 | +5.2% | 11.58% | +41.9% |
| GLPG | Buy | GALAPAGOS NVspon adr | $164,013,083 | -0.9% | 4,244,645 | +13.8% | 5.28% | +4.8% |
| ANAB | ANAPTYSBIO INC | $163,657,482 | -29.8% | 7,521,024 | 0.0% | 5.27% | -25.7% | |
| XNCR | XENCOR INC | $147,329,371 | +7.1% | 5,282,516 | 0.0% | 4.74% | +13.3% | |
| MORF | Sell | MORPHIC HLDG INC | $144,799,800 | +37.0% | 3,846,966 | -2.6% | 4.66% | +44.9% |
| RVMD | Buy | REVOLUTION MEDICINES INC | $115,928,284 | +9.2% | 5,352,183 | +20.0% | 3.73% | +15.5% |
| ACAD | ACADIA PHARMACEUTICALS INC | $112,759,635 | +18.2% | 5,991,479 | 0.0% | 3.63% | +25.1% | |
| ARVN | Buy | ARVINAS INC | $101,569,968 | -4.9% | 3,717,788 | +19.0% | 3.27% | +0.6% |
| Buy | ZYMEWORKS INC | $91,190,756 | +53.3% | 10,087,473 | +33.3% | 2.94% | +62.2% | |
| SWTX | SPRINGWORKS THERAPEUTICS INC | $89,065,754 | -1.0% | 3,460,208 | 0.0% | 2.87% | +4.7% | |
| KURA | KURA ONCOLOGY INC | $81,187,277 | -1.5% | 6,638,371 | 0.0% | 2.61% | +4.3% | |
| RLAY | RELAY THERAPEUTICS INC | $68,578,181 | +10.2% | 4,163,824 | 0.0% | 2.21% | +16.6% | |
| JANX | Buy | JANUX THERAPEUTICS INC | $46,445,681 | +148.1% | 3,838,486 | +170.1% | 1.50% | +162.5% |
| VYGR | Sell | VOYAGER THERAPEUTICS INC | $29,695,119 | +2.4% | 3,851,507 | -19.0% | 0.96% | +8.3% |
| DYN | DYNE THERAPEUTICS INC | $26,753,864 | -0.6% | 2,322,384 | 0.0% | 0.86% | +5.3% | |
| NGM | NGM BIOPHARMACEUTICALS INC | $26,256,913 | -18.7% | 6,435,518 | 0.0% | 0.85% | -13.9% | |
| ALEC | ALECTOR INC | $25,110,032 | -32.9% | 4,056,548 | 0.0% | 0.81% | -29.0% | |
| KYMR | KYMERA THERAPEUTICS INC | $23,588,236 | +18.7% | 796,093 | 0.0% | 0.76% | +25.6% | |
| EWTX | EDGEWISE THERAPEUTICS INC | $23,299,604 | -25.4% | 3,493,194 | 0.0% | 0.75% | -21.1% | |
| NUVB | NUVATION BIO INC | $23,068,261 | -13.5% | 13,896,543 | 0.0% | 0.74% | -8.5% | |
| ALLO | ALLOGENE THERAPEUTICS INC | $22,171,708 | -21.5% | 4,488,200 | 0.0% | 0.71% | -16.9% | |
| CNTA | Buy | CENTESSA PHARMACEUTICALS PLCsponsored ads | $21,632,299 | +33.4% | 5,618,779 | +7.4% | 0.70% | +41.1% |
| CRNX | CRINETICS PHARMACEUTICALS IN | $21,364,024 | -12.2% | 1,330,263 | 0.0% | 0.69% | -7.2% | |
| GRPH | Buy | GRAPHITE BIO INC | $20,919,193 | +10.3% | 8,538,446 | +49.5% | 0.67% | +16.8% |
| AVIR | ATEA PHARMACEUTICALS INC | $20,719,284 | -30.4% | 6,184,861 | 0.0% | 0.67% | -26.3% | |
| ACET | ADICET BIO INC | $20,509,632 | -35.6% | 3,560,700 | 0.0% | 0.66% | -31.9% | |
| ORIC | ORIC PHARMACEUTICALS INC | $19,482,988 | -3.2% | 3,418,068 | 0.0% | 0.63% | +2.3% | |
| TANGO THERAPEUTICS INC | $16,595,585 | -45.5% | 4,201,414 | 0.0% | 0.53% | -42.4% | ||
| OVID | OVID THERAPEUTICS INC | $15,782,892 | +38.7% | 6,117,400 | 0.0% | 0.51% | +46.8% | |
| KDNY | Sell | CHINOOK THERAPEUTICS INC | $10,314,483 | -42.9% | 445,550 | -35.4% | 0.33% | -39.6% |
| GBIO | New | GENERATION BIO CO | $8,413,290 | – | 1,956,579 | +100.0% | 0.27% | – |
| PSTX | POSEIDA THERAPEUTICS INC | $8,162,000 | -41.9% | 2,650,000 | 0.0% | 0.26% | -38.4% | |
| New | THIRD HARMONIC BIO INC | $7,424,743 | – | 1,802,122 | +100.0% | 0.24% | – | |
| PRIME MEDICINE INC | $7,380,000 | -33.8% | 600,000 | 0.0% | 0.24% | -29.8% | ||
| PRQR | New | PROQR THRAPEUTICS N V | $6,182,783 | – | 2,902,715 | +100.0% | 0.20% | – |
| BEAM | New | BEAM THERAPEUTICS INC | $6,080,856 | – | 198,591 | +100.0% | 0.20% | – |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | $4,568,542 | -25.7% | 415,322 | 0.0% | 0.15% | -21.4% | |
| MGNX | Sell | MACROGENICS INC | $4,439,607 | -40.8% | 619,192 | -44.6% | 0.14% | -37.3% |
| ALGS | ALIGOS THERAPEUTICS INC | $3,450,867 | -8.3% | 3,948,360 | 0.0% | 0.11% | -3.5% | |
| CGEM | Sell | CULLINAN ONCOLOGY INC | $2,520,774 | -76.9% | 246,410 | -76.2% | 0.08% | -75.6% |
| TPST | TEMPEST THERAPEUTICS INC | $2,392,542 | +101.7% | 1,031,268 | 0.0% | 0.08% | +113.9% | |
| BDTX | Buy | BLACK DIAMOND THERAPEUTICS I | $2,251,168 | +343.3% | 1,191,094 | +322.2% | 0.07% | +380.0% |
| SURF | Sell | SURFACE ONCOLOGY INC | $2,154,372 | -33.1% | 3,082,959 | -21.4% | 0.07% | -29.6% |
| ERASCA INC | $2,042,107 | -30.2% | 678,441 | 0.0% | 0.07% | -25.8% | ||
| EUCR | EUCRATES BIOMEDICAL ACQU COR | $2,028,000 | +1.5% | 200,000 | 0.0% | 0.06% | +6.6% | |
| HOOK | HOOKIPA PHARMA INC | $1,820,488 | -9.1% | 2,473,489 | 0.0% | 0.06% | -3.3% | |
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $1,599,133 | -13.5% | 963,333 | 0.0% | 0.05% | -8.9% | |
| GRCL | Sell | GRACELL BIOTECHNOLOGIES INCsponsored ads | $1,486,043 | -80.7% | 798,948 | -76.1% | 0.05% | -79.5% |
| NEWAMSTERDAM PHARMA COMPANY*w exp 11/22/202 | $883,978 | +21.7% | 66,665 | 0.0% | 0.03% | +27.3% | ||
| EUCRW | EUCRATES BIOMEDICAL ACQU COR*w exp 10/23/202 | $675,993 | +1.5% | 66,666 | 0.0% | 0.02% | +10.0% | |
| KRON | KRONOS BIO INC | $477,099 | -9.9% | 326,780 | 0.0% | 0.02% | -6.2% | |
| CMAXW | CAREMAX INC*w exp 06/08/202 | $267,000 | -26.8% | 100,000 | 0.0% | 0.01% | -18.2% | |
| SELB | Sell | SELECTA BIOSCIENCES INC | $278,000 | -93.0% | 200,000 | -94.3% | 0.01% | -92.5% |
| CYT | New | CYTEIR THERAPEUTICS INC | $79,758 | – | 43,823 | +100.0% | 0.00% | – |
| ITOS | Sell | ITEOS THERAPEUTICS INC | $17,693 | -97.8% | 1,300 | -96.8% | 0.00% | -95.8% |
| SURROZEN INC*w exp 08/01/203 | $40,132 | +3.5% | 66,665 | 0.0% | 0.00% | 0.0% | ||
| ARYD | Exit | ARYA SCIENCES ACQU CORP IVcl a | $0 | – | -150,000 | -100.0% | -0.05% | – |
| Exit | ABEONA THERAPEUTICS INC | $0 | – | -1,086,956 | -100.0% | -0.10% | – | |
| PRAX | Exit | PRAXIS PRECISION MEDICINES I | $0 | – | -1,585,324 | -100.0% | -0.12% | – |
| HSAQ | Exit | HEALTH SCIENCES ACQ CORP 2 | $0 | – | -400,000 | -100.0% | -0.12% | – |
| DTIL | Exit | PRECISION BIOSCIENCES INC | $0 | – | -5,035,971 | -100.0% | -0.18% | – |
| IMTX | Exit | IMMATICS N.V | $0 | – | -743,000 | -100.0% | -0.20% | – |
| DSGN | Exit | DESIGN THERAPEUTICS INC | $0 | – | -884,903 | -100.0% | -0.28% | – |
| BCAB | Exit | BIOATLA INC | $0 | – | -1,124,439 | -100.0% | -0.28% | – |
| AVEO | Exit | AVEO PHARMACEUTICALS INC | $0 | – | -650,489 | -100.0% | -0.30% | – |
| GERN | Exit | GERON CORP | $0 | – | -4,028,507 | -100.0% | -0.30% | – |
| Exit | 2SEVENTY BIO INC | $0 | – | -1,143,494 | -100.0% | -0.33% | – | |
| Exit | VENTYX BIOSCIENCES INC | $0 | – | -400,000 | -100.0% | -0.40% | – | |
| ZLAB | Exit | ZAI LAB LTDadr | $0 | – | -2,157,686 | -100.0% | -2.02% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-05-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.