$2.9 Billion is the total value of EcoR1 Capital, LLC's 80 reported holdings in Q2 2022. The portfolio turnover from Q1 2022 to Q2 2022 was 40.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | $314,513,000 | -25.8% | 11,584,280 | 0.0% | 10.86% | -18.1% | |
| APLS | APELLIS PHARMACEUTICALS INC | $234,395,000 | -11.0% | 5,183,431 | 0.0% | 8.09% | -1.8% | |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $214,996,000 | +33.0% | 2,868,145 | +38.6% | 7.42% | +46.7% |
| SGEN | New | SEAGEN INC | $178,467,000 | – | 1,008,628 | +100.0% | 6.16% | – |
| GLPG | Buy | GALAPAGOS NVspon adr | $178,420,000 | -10.0% | 3,197,500 | +0.1% | 6.16% | -0.7% |
| ANAB | ANAPTYSBIO INC | $152,677,000 | -17.9% | 7,521,024 | 0.0% | 5.27% | -9.5% | |
| XNCR | Buy | XENCOR INC | $144,580,000 | +9.1% | 5,282,416 | +6.3% | 4.99% | +20.4% |
| ARVN | Buy | ARVINAS INC | $131,460,000 | +29.9% | 3,123,300 | +107.7% | 4.54% | +43.3% |
| KURA | KURA ONCOLOGY INC | $121,681,000 | +14.0% | 6,638,371 | 0.0% | 4.20% | +25.8% | |
| MORF | MORPHIC HLDG INC | $85,749,000 | -46.0% | 3,951,566 | 0.0% | 2.96% | -40.4% | |
| ACAD | ACADIA PHARMACEUTICALS INC | $84,420,000 | -41.8% | 5,991,479 | 0.0% | 2.91% | -35.8% | |
| ZLAB | Buy | ZAI LAB LTadr | $84,338,000 | -13.7% | 2,431,885 | +9.4% | 2.91% | -4.8% |
| RVMD | Buy | REVOLUTION MEDICINES INC | $83,380,000 | +156.5% | 4,278,069 | +235.8% | 2.88% | +183.0% |
| RLAY | Buy | RELAY THERAPEUTICS INC | $62,369,000 | -9.1% | 3,723,541 | +62.5% | 2.15% | +0.4% |
| RETA | REATA PHARMACEUTICALS INCcl a | $60,039,000 | -7.2% | 1,975,611 | 0.0% | 2.07% | +2.3% | |
| ALLO | New | ALLOGENE THERAPEUTICS INC | $51,165,000 | – | 4,488,200 | +100.0% | 1.77% | – |
| ARGX | ARGENX SEsponsored adr | $47,360,000 | +20.2% | 125,000 | 0.0% | 1.64% | +32.6% | |
| 2SEVENTY BIO INC | $46,146,000 | -22.6% | 3,495,943 | 0.0% | 1.59% | -14.6% | ||
| NUVB | NUVATION BIO INC | $45,025,000 | -38.4% | 13,896,543 | 0.0% | 1.55% | -32.1% | |
| AVIR | ATEA PHARMACEUTICALS INC | $45,019,000 | -1.7% | 6,340,639 | 0.0% | 1.55% | +8.5% | |
| CERE | CEREVEL THERAPEUTICS HLDNG I | $43,527,000 | -24.5% | 1,646,260 | 0.0% | 1.50% | -16.7% | |
| ALEC | Sell | ALECTOR INC | $41,215,000 | -49.6% | 4,056,548 | -29.3% | 1.42% | -44.4% |
| RNA | AVIDITY BIOSCIENCES INC | $40,096,000 | -21.3% | 2,759,505 | 0.0% | 1.38% | -13.2% | |
| DSGN | Buy | DESIGN THERAPEUTICS INC | $36,878,000 | -3.7% | 2,634,178 | +11.1% | 1.27% | +6.3% |
| VYGR | Buy | VOYAGER THERAPEUTICS INC | $28,096,000 | +3.6% | 4,753,907 | +33.6% | 0.97% | +14.4% |
| CRNX | Buy | CRINETICS PHARMACEUTICALS IN | $24,809,000 | +43.0% | 1,330,263 | +68.3% | 0.86% | +57.6% |
| GERN | Sell | GERON CORP | $21,962,000 | +13.0% | 14,168,988 | -0.8% | 0.76% | +24.7% |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | $19,083,000 | +10.6% | 895,503 | 0.0% | 0.66% | +22.0% | |
| EWTX | EDGEWISE THERAPEUTICS INC | $18,784,000 | -17.9% | 2,359,808 | 0.0% | 0.65% | -9.5% | |
| JANX | JANUX THERAPEUTICS INC | $17,354,000 | -14.9% | 1,421,319 | 0.0% | 0.60% | -6.1% | |
| VENTYX BIOSCIENCES INC | $15,899,000 | -9.9% | 1,300,000 | 0.0% | 0.55% | -0.5% | ||
| EXEL | New | EXELIXIS INCcall | $15,823,000 | – | 760,000 | +100.0% | 0.55% | – |
| ORIC | ORIC PHARMACEUTICALS INC | $15,313,000 | -16.1% | 3,418,068 | 0.0% | 0.53% | -7.4% | |
| CGEM | New | CULLINAN ONCOLOGY INC | $14,998,000 | – | 1,169,889 | +100.0% | 0.52% | – |
| INCY | New | INCYTE CORP | $13,886,000 | – | 182,783 | +100.0% | 0.48% | – |
| OVID | OVID THERAPEUTICS INC | $13,152,000 | -31.5% | 6,117,400 | 0.0% | 0.45% | -24.5% | |
| KDNY | CHINOOK THERAPEUTICS INC | $12,068,000 | +6.9% | 690,000 | 0.0% | 0.42% | +18.1% | |
| GRCL | Buy | GRACELL BIOTECHNOLOGIES INCsponsored ads | $10,567,000 | +190.8% | 1,921,310 | +23.2% | 0.36% | +220.2% |
| Buy | TANGO THERAPEUTICS INC | $10,428,000 | +80.5% | 2,302,065 | +202.1% | 0.36% | +98.9% | |
| AKUS | AKOUOS INC | $9,267,000 | -1.3% | 1,975,984 | 0.0% | 0.32% | +8.8% | |
| HOOK | HOOKIPA PHARMA INC | $8,150,000 | -28.5% | 5,000,000 | 0.0% | 0.28% | -21.3% | |
| DTIL | New | PRECISION BIOSCIENCES INC | $8,058,000 | – | 5,035,971 | +100.0% | 0.28% | – |
| SURF | SURFACE ONCOLOGY INC | $7,631,000 | -44.2% | 4,653,000 | 0.0% | 0.26% | -38.6% | |
| NGM | NGM BIOPHARMACEUTICALS INC | $6,937,000 | -15.9% | 541,108 | 0.0% | 0.24% | -7.4% | |
| FLAC | FRAZIER LIFESCIENCES ACQU CO | $5,800,000 | +0.4% | 587,615 | 0.0% | 0.20% | +10.5% | |
| ITOS | Buy | ITEOS THERAPEUTICS INC | $5,768,000 | +146.2% | 279,999 | +284.5% | 0.20% | +172.6% |
| JYAC | JIYA ACQUISITION CORP | $4,940,000 | +0.5% | 500,000 | 0.0% | 0.17% | +11.0% | |
| ALGS | ALIGOS THERAPEUTICS INC | $4,778,000 | -43.7% | 3,948,360 | 0.0% | 0.16% | -38.0% | |
| SELB | New | SELECTA BIOSCIENCES INC | $4,585,000 | – | 3,500,000 | +100.0% | 0.16% | – |
| AVEO | New | AVEO PHARMACEUTICALS INC | $4,248,000 | – | 647,489 | +100.0% | 0.15% | – |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $3,984,000 | +0.5% | 400,000 | 0.0% | 0.14% | +11.3% | |
| ERASCA INC | $3,779,000 | -35.2% | 678,441 | 0.0% | 0.13% | -29.0% | ||
| GRPH | Buy | GRAPHITE BIO INC | $3,196,000 | -38.8% | 1,162,179 | +13.5% | 0.11% | -32.5% |
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $3,121,000 | -38.4% | 963,333 | 0.0% | 0.11% | -32.1% | |
| CLDX | New | CELLDEX THERAPEUTICS INC NEWput | $3,106,000 | – | 115,200 | +100.0% | 0.11% | – |
| SBTX | Buy | SILVERBACK THERAPEUTICS INC | $2,440,000 | +110.9% | 575,359 | +74.6% | 0.08% | +133.3% |
| TPST | New | TEMPEST THERAPEUTICS INC | $2,217,000 | – | 1,031,268 | +100.0% | 0.08% | – |
| KNTE | KINNATE BIOPHARMA INC | $2,207,000 | +12.0% | 175,000 | 0.0% | 0.08% | +22.6% | |
| FVAM | 5 01 ACQUISITION CORP | $1,980,000 | +0.5% | 200,000 | 0.0% | 0.07% | +9.7% | |
| EUCR | EUCRATES BIOMEDICAL ACQU COR | $1,980,000 | +0.6% | 200,000 | 0.0% | 0.07% | +9.7% | |
| BLSA | BCLS ACQUISITION CORP | $1,980,000 | +0.3% | 200,000 | 0.0% | 0.07% | +9.7% | |
| VERV | VERVE THERAPEUTICS INC | $1,507,000 | -33.0% | 98,593 | 0.0% | 0.05% | -25.7% | |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $1,472,000 | +0.1% | 150,000 | 0.0% | 0.05% | +10.9% | |
| DYN | DYNE THERAPEUTICS INC | $1,477,000 | -28.8% | 215,000 | 0.0% | 0.05% | -21.5% | |
| MRSN | Sell | MERSANA THERAPEUTICS INC | $1,437,000 | +10.3% | 310,960 | -4.8% | 0.05% | +22.0% |
| OLMA | New | OLEMA PHARMACEUTICALS INC | $1,440,000 | – | 353,701 | +100.0% | 0.05% | – |
| CNTA | Sell | CENTESSA PHARMACEUTICALS PLCsponsored ads | $1,424,000 | -65.1% | 292,320 | -35.7% | 0.05% | -61.7% |
| ADVM | ADVERUM BIOTECHNOLOGIES INC | $1,256,000 | -8.4% | 1,046,700 | 0.0% | 0.04% | 0.0% | |
| KRON | KRONOS BIO INC | $1,189,000 | -49.7% | 326,780 | 0.0% | 0.04% | -44.6% | |
| TMPM | TURMERIC ACQUISITION CORPcl a | $993,000 | +0.8% | 100,000 | 0.0% | 0.03% | +9.7% | |
| FLACW | FRAZIER LIFESCIENCES ACQU CO*w exp 11/30/202 | $658,000 | +0.5% | 66,665 | 0.0% | 0.02% | +15.0% | |
| EUCRW | New | EUCRATES BIOMEDICAL ACQU COR*w exp 10/23/202 | $660,000 | – | 66,666 | +100.0% | 0.02% | – |
| PARDES BIOSCIENCES INC | $614,000 | -56.0% | 200,000 | 0.0% | 0.02% | -52.3% | ||
| PRAX | New | PRAXIS PRECISION MEDICINES I | $515,000 | – | 210,100 | +100.0% | 0.02% | – |
| OMEG | OMEGA ALPHA SPACcl a | $493,000 | +0.4% | 50,000 | 0.0% | 0.02% | +13.3% | |
| EVLO | New | EVELO BIOSCIENCES INC | $423,000 | – | 200,417 | +100.0% | 0.02% | – |
| CMAXW | CAREMAX INC*w exp 06/08/202 | $363,000 | -51.4% | 100,000 | 0.0% | 0.01% | -43.5% | |
| TMPMW | TURMERIC ACQUISITION CORP*w exp 10/08/202 | $331,000 | +0.9% | 33,333 | 0.0% | 0.01% | +10.0% | |
| BOLT | BOLT BIOTHERAPEUTICS INC | $306,000 | -25.5% | 150,000 | 0.0% | 0.01% | -15.4% | |
| SURROZEN INC*w exp 08/01/203 | $200,000 | -0.5% | 66,665 | 0.0% | 0.01% | +16.7% | ||
| RDUS | Exit | RADIUS HEALTH INC | $0 | – | -35,000 | -100.0% | -0.01% | – |
| EUCRW | Exit | EUCRATES BIOMEDICAL ACQU CORcall | $0 | – | -66,666 | -100.0% | -0.02% | – |
| Exit | CARIBOU BIOSCIENCES INC | $0 | – | -75,000 | -100.0% | -0.02% | – | |
| RPTX | Exit | REPARE THERAPEUTICS INC | $0 | – | -50,000 | -100.0% | -0.02% | – |
| AMTI | Exit | APPLIED MOLECULAR TRANS INC | $0 | – | -131,693 | -100.0% | -0.03% | – |
| BCEL | Exit | ATRECA INC | $0 | – | -358,780 | -100.0% | -0.04% | – |
| ACIU | Exit | AC IMMUNE SA | $0 | – | -485,005 | -100.0% | -0.06% | – |
| HLXA | Exit | HELIX ACQUISITION CORP | $0 | – | -200,000 | -100.0% | -0.07% | – |
| SLDB | Exit | SOLID BIOSCIENCES INC | $0 | – | -2,565,102 | -100.0% | -0.10% | – |
| NRIX | Exit | NURIX THERAPEUTICS INC | $0 | – | -254,473 | -100.0% | -0.11% | – |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -200,000 | -100.0% | -0.15% | – |
| ZNTL | Exit | ZENTALIS PHARMACEUTICALS INC | $0 | – | -115,236 | -100.0% | -0.17% | – |
| IGMS | Exit | IGM BIOSCIENCES INC | $0 | – | -298,597 | -100.0% | -0.25% | – |
| PTGX | Exit | PROTAGONIST THERAPEUTICS INC | $0 | – | -381,711 | -100.0% | -0.28% | – |
| PMVP | Exit | PMV PHARMACEUTICALS INC | $0 | – | -649,786 | -100.0% | -0.42% | – |
| SWTX | Exit | SPRINGWORKS THERAPEUTICS INC | $0 | – | -325,881 | -100.0% | -0.58% | – |
| EXEL | Exit | EXELIXIS INC | $0 | – | -951,333 | -100.0% | -0.68% | – |
| BCYC | Exit | BICYCLE THERAPEUTICS PLCsponsored ads | $0 | – | -547,453 | -100.0% | -0.75% | – |
| PCVX | Exit | VAXCYTE INC | $0 | – | -1,304,741 | -100.0% | -0.99% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -500,622 | -100.0% | -1.29% | – |
| RCUS | Exit | ARCUS BIOSCIENCES INC | $0 | – | -3,265,101 | -100.0% | -3.22% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-08-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.