$3.2 Billion is the total value of EcoR1 Capital, LLC's 87 reported holdings in Q1 2022. The portfolio turnover from Q4 2021 to Q1 2022 was 46.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PRTA | Buy | PROTHENA CORP PLC | $423,637,000 | -24.0% | 11,584,280 | +2.7% | 13.25% | -25.4% |
| APLS | Buy | APELLIS PHARMACEUTICALS INC | $263,370,000 | +38.1% | 5,183,431 | +28.5% | 8.24% | +35.5% |
| GLPG | Buy | GALAPAGOS NVspon adr | $198,193,000 | +61.6% | 3,195,624 | +43.7% | 6.20% | +58.6% |
| ANAB | ANAPTYSBIO INC | $186,070,000 | -28.8% | 7,521,024 | 0.0% | 5.82% | -30.1% | |
| SRPT | New | SAREPTA THERAPEUTICS INC | $161,680,000 | – | 2,069,634 | +100.0% | 5.06% | – |
| MORF | MORPHIC HLDG INC | $158,655,000 | -15.3% | 3,951,566 | 0.0% | 4.96% | -16.8% | |
| ACAD | Buy | ACADIA PHARMACEUTICALS INC | $145,114,000 | +103.1% | 5,991,479 | +95.8% | 4.54% | +99.4% |
| XNCR | Buy | XENCOR INC | $132,566,000 | -32.7% | 4,968,756 | +1.3% | 4.15% | -33.9% |
| KURA | Buy | KURA ONCOLOGY INC | $106,745,000 | +104.7% | 6,638,371 | +78.2% | 3.34% | +100.9% |
| RCUS | Sell | ARCUS BIOSCIENCES INC | $103,047,000 | -53.9% | 3,265,101 | -40.9% | 3.22% | -54.8% |
| ARVN | Buy | ARVINAS INC | $101,214,000 | +845.7% | 1,503,929 | +1054.2% | 3.17% | +828.4% |
| ZLAB | New | ZAI LAB LTDadr | $97,777,000 | – | 2,223,212 | +100.0% | 3.06% | – |
| ALEC | Buy | ALECTOR INC | $81,773,000 | -20.7% | 5,738,448 | +14.9% | 2.56% | -22.2% |
| NUVB | NUVATION BIO INC | $73,096,000 | -38.1% | 13,896,543 | 0.0% | 2.29% | -39.2% | |
| RLAY | Buy | RELAY THERAPEUTICS INC | $68,583,000 | +25.5% | 2,291,441 | +28.8% | 2.14% | +23.2% |
| RETA | New | REATA PHARMACEUTICALS INCcl a | $64,721,000 | – | 1,975,611 | +100.0% | 2.02% | – |
| Buy | 2SEVENTY BIO INC | $59,641,000 | +21.4% | 3,495,943 | +82.4% | 1.87% | +19.2% | |
| CERE | New | CEREVEL THERAPEUTICS HLDNG I | $57,636,000 | – | 1,646,260 | +100.0% | 1.80% | – |
| RNA | AVIDITY BIOSCIENCES INC | $50,968,000 | -22.3% | 2,759,505 | 0.0% | 1.59% | -23.7% | |
| AVIR | Buy | ATEA PHARMACEUTICALS INC | $45,779,000 | -4.8% | 6,340,639 | +17.9% | 1.43% | -6.5% |
| MRTX | New | MIRATI THERAPEUTICS INC | $41,161,000 | – | 500,622 | +100.0% | 1.29% | – |
| ARGX | New | ARGENX SEsponsored adr | $39,414,000 | – | 125,000 | +100.0% | 1.23% | – |
| DSGN | Buy | DESIGN THERAPEUTICS INC | $38,299,000 | -16.9% | 2,371,445 | +10.1% | 1.20% | -18.4% |
| RVMD | New | REVOLUTION MEDICINES INC | $32,502,000 | – | 1,274,097 | +100.0% | 1.02% | – |
| PCVX | Buy | VAXCYTE INC | $31,509,000 | +6265.5% | 1,304,741 | +6172.8% | 0.99% | +6062.5% |
| VYGR | VOYAGER THERAPEUTICS INC | $27,108,000 | +181.2% | 3,557,507 | 0.0% | 0.85% | +176.2% | |
| BCYC | New | BICYCLE THERAPEUTICS PLCsponsored ads | $24,022,000 | – | 547,453 | +100.0% | 0.75% | – |
| EWTX | Buy | EDGEWISE THERAPEUTICS INC | $22,890,000 | +17.1% | 2,359,808 | +84.5% | 0.72% | +14.9% |
| EXEL | New | EXELIXIS INC | $21,567,000 | – | 951,333 | +100.0% | 0.68% | – |
| JANX | Buy | JANUX THERAPEUTICS INC | $20,382,000 | -26.8% | 1,421,319 | +0.7% | 0.64% | -28.2% |
| GERN | New | GERON CORP | $19,429,000 | – | 14,285,714 | +100.0% | 0.61% | – |
| OVID | Buy | OVID THERAPEUTICS INC | $19,209,000 | -1.6% | 6,117,400 | +0.6% | 0.60% | -3.4% |
| SWTX | New | SPRINGWORKS THERAPEUTICS INC | $18,393,000 | – | 325,881 | +100.0% | 0.58% | – |
| ORIC | Sell | ORIC PHARMACEUTICALS INC | $18,252,000 | -64.2% | 3,418,068 | -1.5% | 0.57% | -64.9% |
| VENTYX BIOSCIENCES INC | $17,641,000 | -31.7% | 1,300,000 | 0.0% | 0.55% | -32.9% | ||
| CRNX | Buy | CRINETICS PHARMACEUTICALS IN | $17,345,000 | +3.4% | 790,209 | +33.9% | 0.54% | +1.7% |
| ARQT | New | ARCUTIS BIOTHERAPEUTICS INC | $17,247,000 | – | 895,503 | +100.0% | 0.54% | – |
| SURF | New | SURFACE ONCOLOGY INC | $13,680,000 | – | 4,653,000 | +100.0% | 0.43% | – |
| PMVP | Buy | PMV PHARMACEUTICALS INC | $13,529,000 | +1071.3% | 649,786 | +1199.6% | 0.42% | +1043.2% |
| HOOK | New | HOOKIPA PHARMA INC | $11,400,000 | – | 5,000,000 | +100.0% | 0.36% | – |
| KDNY | New | CHINOOK THERAPEUTICS INC | $11,288,000 | – | 690,000 | +100.0% | 0.35% | – |
| AKUS | AKOUOS INC | $9,386,000 | -44.1% | 1,975,984 | 0.0% | 0.29% | -45.0% | |
| PTGX | Sell | PROTAGONIST THERAPEUTICS INC | $9,039,000 | -90.0% | 381,711 | -85.5% | 0.28% | -90.2% |
| ALGS | Buy | ALIGOS THERAPEUTICS INC | $8,489,000 | +685.3% | 3,948,360 | +4236.8% | 0.27% | +682.4% |
| NGM | New | NGM BIOPHARMACEUTICALS INC | $8,252,000 | – | 541,108 | +100.0% | 0.26% | – |
| IGMS | New | IGM BIOSCIENCES INC | $7,981,000 | – | 298,597 | +100.0% | 0.25% | – |
| Sell | ERASCA INC | $5,835,000 | -46.5% | 678,441 | -3.1% | 0.18% | -47.4% | |
| Sell | TANGO THERAPEUTICS INC | $5,776,000 | -59.4% | 761,971 | -41.4% | 0.18% | -60.0% | |
| FLAC | FRAZIER LIFESCIENCES ACQU CO CL A | $5,776,000 | +0.8% | 587,615 | 0.0% | 0.18% | -1.1% | |
| ZNTL | New | ZENTALIS PHARMACEUTICALS INC | $5,317,000 | – | 115,236 | +100.0% | 0.17% | – |
| GRPH | Buy | GRAPHITE BIO INC | $5,224,000 | -39.0% | 1,024,279 | +48.7% | 0.16% | -40.3% |
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $5,067,000 | -38.1% | 963,333 | 0.0% | 0.16% | -39.1% | |
| JYAC | JIYA ACQUISITION CORP | $4,915,000 | +0.6% | 500,000 | 0.0% | 0.15% | -1.3% | |
| CCCC | C4 THERAPEUTICS INC | $4,852,000 | -24.7% | 200,000 | 0.0% | 0.15% | -25.9% | |
| CNTA | Sell | CENTESSA PHARMACEUTICALS PLCsponsored ads | $4,077,000 | -59.0% | 454,545 | -48.5% | 0.13% | -59.6% |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 ORD | $3,964,000 | -1.7% | 400,000 | 0.0% | 0.12% | -3.1% | |
| GRCL | New | GRACELL BIOTECHNOLOGIES INCsponsored ads | $3,634,000 | – | 1,559,710 | +100.0% | 0.11% | – |
| NRIX | Sell | NURIX THERAPEUTICS INC | $3,565,000 | -60.2% | 254,473 | -17.8% | 0.11% | -60.8% |
| SLDB | Sell | SOLID BIOSCIENCES INC | $3,078,000 | -80.9% | 2,565,102 | -72.1% | 0.10% | -81.3% |
| KRON | Sell | KRONOS BIO INC | $2,363,000 | -55.1% | 326,780 | -15.6% | 0.07% | -56.0% |
| ITOS | Sell | ITEOS THERAPEUTICS INC | $2,343,000 | -96.1% | 72,821 | -94.4% | 0.07% | -96.2% |
| VERV | Sell | VERVE THERAPEUTICS INC | $2,250,000 | -39.0% | 98,593 | -1.4% | 0.07% | -40.2% |
| HLXA | HELIX ACQUISITION CORP | $2,220,000 | +12.2% | 200,000 | 0.0% | 0.07% | +9.5% | |
| DYN | DYNE THERAPEUTICS INC | $2,073,000 | -18.9% | 215,000 | 0.0% | 0.06% | -19.8% | |
| BLSA | BCLS ACQUISITION CORP | $1,974,000 | +0.7% | 200,000 | 0.0% | 0.06% | 0.0% | |
| KNTE | KINNATE BIOPHARMA INC | $1,971,000 | -36.4% | 175,000 | 0.0% | 0.06% | -37.4% | |
| EUCR | EUCRATES BIOMEDICAL ACQU COR | $1,968,000 | +0.8% | 200,000 | 0.0% | 0.06% | 0.0% | |
| FVAM | 5 01 ACQUISITION CORP | $1,970,000 | 0.0% | 200,000 | 0.0% | 0.06% | -1.6% | |
| ACIU | Sell | AC IMMUNE SA | $1,940,000 | -47.7% | 485,005 | -35.3% | 0.06% | -48.3% |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $1,470,000 | -1.1% | 150,000 | 0.0% | 0.05% | -2.1% | |
| Sell | PARDES BIOSCIENCES INC | $1,394,000 | -94.7% | 200,000 | -87.5% | 0.04% | -94.7% | |
| ADVM | ADVERUM BIOTECHNOLOGIES INC | $1,371,000 | -25.6% | 1,046,700 | 0.0% | 0.04% | -27.1% | |
| MRSN | New | MERSANA THERAPEUTICS INC | $1,303,000 | – | 326,578 | +100.0% | 0.04% | – |
| BCEL | New | ATRECA INC | $1,137,000 | – | 358,780 | +100.0% | 0.04% | – |
| SBTX | Sell | SILVERBACK THERAPEUTICS INC | $1,157,000 | -83.6% | 329,537 | -68.9% | 0.04% | -84.0% |
| TMPM | TURMERIC ACQUISITION CORPcl a | $985,000 | +0.3% | 100,000 | 0.0% | 0.03% | 0.0% | |
| AMTI | Sell | APPLIED MOLECULAR TRANS INC | $990,000 | -82.3% | 131,693 | -67.1% | 0.03% | -82.6% |
| CMAXW | CAREMAX INC*w exp 06/08/202 | $747,000 | -2.7% | 100,000 | 0.0% | 0.02% | -4.2% | |
| RPTX | REPARE THERAPEUTICS INC | $712,000 | -32.5% | 50,000 | 0.0% | 0.02% | -35.3% | |
| CARIBOU BIOSCIENCES INC | $689,000 | -39.1% | 75,000 | 0.0% | 0.02% | -38.9% | ||
| EUCRW | New | EUCRATES BIOMEDICAL ACQU CORcall | $656,000 | – | 66,666 | +100.0% | 0.02% | – |
| FLACW | FRAZIER LIFESCIENCES ACQU CO*w exp 11/30/202 | $655,000 | +0.8% | 66,665 | 0.0% | 0.02% | -4.8% | |
| OMEG | OMEGA ALPHA SPACcl a | $491,000 | +0.4% | 50,000 | 0.0% | 0.02% | -6.2% | |
| BOLT | BOLT BIOTHERAPEUTICS INC | $411,000 | -44.1% | 150,000 | 0.0% | 0.01% | -43.5% | |
| RDUS | New | RADIUS HEALTH INC | $309,000 | – | 35,000 | +100.0% | 0.01% | – |
| TMPMW | TURMERIC ACQUISITION CORP*w exp 10/08/202 | $328,000 | +0.3% | 33,333 | 0.0% | 0.01% | 0.0% | |
| SURROZEN INC*w exp 08/01/203 | $201,000 | -53.1% | 66,665 | 0.0% | 0.01% | -57.1% | ||
| EUCRW | Exit | EUCRATES BIOMEDICAL ACQU COR*w exp 10/23/202 | $0 | – | -66,666 | -100.0% | -0.02% | – |
| GLUE | Exit | MONTE ROSA THERAPEUTICS INC | $0 | – | -37,593 | -100.0% | -0.02% | – |
| VTVT | Exit | VTV THERAPEUTICS INCcl a | $0 | – | -834,333 | -100.0% | -0.03% | – |
| GRTS | Exit | GRITSTONE BIO INCcall | $0 | – | -307,000 | -100.0% | -0.13% | – |
| NLTX | Exit | NEOLEUKIN THERAPEUTICS INC | $0 | – | -860,619 | -100.0% | -0.13% | – |
| IMVT | Exit | IMMUNOVANT INC | $0 | – | -1,140,819 | -100.0% | -0.31% | – |
| LEGN | Exit | LEGEND BIOTECH CORPsponsored ads | $0 | – | -307,594 | -100.0% | -0.46% | – |
| HALO | Exit | HALOZYME THERAPEUTICS INC | $0 | – | -392,000 | -100.0% | -0.50% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -98,146 | -100.0% | -0.53% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -940,636 | -100.0% | -1.28% | – |
| GRTS | Exit | GRITSTONE BIO INC | $0 | – | -6,012,232 | -100.0% | -2.46% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -1,077,483 | -100.0% | -2.60% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-05-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.