$358 Million is the total value of INTERNATIONAL BIOTECHNOLOGY TRUST PLC's 64 reported holdings in Q1 2023. The portfolio turnover from Q4 2022 to Q1 2023 was 20.6% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SGEN | Buy | SEAGEN INC | $40,510,470 | +89.7% | 200,200 | +20.5% | 11.30% | +71.4% |
| AMGN | Buy | AMGEN INC COM | $22,053,246 | +417.0% | 91,246 | +461.7% | 6.15% | +367.2% |
| INCY | Buy | INCYTE CORP | $20,163,330 | +9.6% | 279,000 | +21.8% | 5.63% | -1.0% |
| HRMY | Buy | HARMONY BIOSCIENCES HLDGS | $18,621,120 | +27.9% | 570,500 | +115.7% | 5.20% | +15.5% |
| ALKS | ALKERMES PLC | $16,716,670 | +8.0% | 593,000 | 0.0% | 4.66% | -2.5% | |
| SUPN | Buy | SUPERNUS PHARMS. | $15,326,465 | +12.1% | 423,500 | +10.4% | 4.28% | +1.3% |
| ITCI | Buy | INTRA-CELLULAR THERAPIES | $13,957,745 | +19.0% | 257,856 | +16.2% | 3.89% | +7.5% |
| RARE | Buy | ULTRAGENYX PHARM. | $10,580,564 | +31.3% | 264,052 | +51.7% | 2.95% | +18.6% |
| EXEL | EXELIXIS INC | $10,545,060 | +21.1% | 543,000 | 0.0% | 2.94% | +9.4% | |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $10,385,430 | – | 33,000 | +100.0% | 2.90% | – |
| QURE | Sell | UNIQURE NV | $9,636,990 | -32.6% | 478,500 | -24.2% | 2.69% | -39.1% |
| ALNY | Buy | ALNYLAM PHARMS. | $9,333,048 | +3.5% | 46,600 | +22.6% | 2.60% | -6.5% |
| REGN | REGENERON PHARMS. | $9,197,552 | +13.8% | 11,200 | 0.0% | 2.57% | +2.8% | |
| MRTX | MIRATI THERAPEUTICS INC | $9,071,920 | -17.9% | 244,000 | 0.0% | 2.53% | -25.9% | |
| SNY | SANOFIsponsored adr | $7,809,270 | +12.5% | 143,500 | 0.0% | 2.18% | +1.6% | |
| VERA | Buy | VERA THERAPEUTICScl a | $7,747,447 | +42.7% | 1,002,257 | +256.3% | 2.16% | +28.9% |
| KDNY | Sell | CHINOOK THERAPEUTICS | $7,407,745 | -16.9% | 319,989 | -6.0% | 2.07% | -24.9% |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $6,380,010 | +53.0% | 28,500 | +90.0% | 1.78% | +38.2% |
| AUPH | AURINIA PHARMACEUTICALS INC | $6,280,154 | +153.5% | 573,530 | 0.0% | 1.75% | +129.0% | |
| ILMN | Sell | ILLUMINA INC | $6,162,310 | -34.4% | 26,500 | -43.0% | 1.72% | -40.8% |
| BIIB | BIOGEN INC | $5,949,628 | +0.4% | 21,400 | 0.0% | 1.66% | -9.2% | |
| RVNC | Buy | REVANCE THERAPEUTICS INC | $5,888,940 | +166.0% | 183,000 | +52.5% | 1.64% | +140.2% |
| BMRN | Buy | BIOMARIN PHARM. | $5,704,883 | +26.4% | 58,656 | +34.4% | 1.59% | +14.2% |
| DYN | Sell | DYNE THERAPEUTICS | $4,988,137 | -32.7% | 433,751 | -32.3% | 1.39% | -39.2% |
| BGNE | Buy | BEIGENE ADRsponsored adr | $4,892,758 | +41.7% | 22,700 | +44.6% | 1.36% | +28.0% |
| KRYS | Buy | KRYSTAL BIOTECH | $4,883,660 | +37.3% | 61,000 | +35.6% | 1.36% | +24.0% |
| GILD | GILEAD SCIENCES | $4,777,169 | -3.3% | 57,584 | 0.0% | 1.33% | -12.6% | |
| AZN | ASTRAZENECA PLC SPONSOREDsponsored adr | $4,511,650 | +2.4% | 65,000 | 0.0% | 1.26% | -7.5% | |
| PTCT | Sell | PTC THERAPEUTICS | $4,504,920 | -18.0% | 93,000 | -35.4% | 1.26% | -25.9% |
| New | ERASCA INC | $4,278,000 | – | 1,426,000 | +100.0% | 1.19% | – | |
| ACAD | Buy | ACADIA PHARMACEUTICALS IN | $4,060,800 | +155.4% | 216,000 | +116.0% | 1.13% | +130.8% |
| GMAB | New | GENMAB A/Ssponsored ads | $3,322,880 | – | 88,000 | +100.0% | 0.93% | – |
| TVTX | Sell | TRAVERE THERAPEUTICS INC | $3,170,107 | -60.2% | 141,019 | -62.8% | 0.88% | -64.0% |
| ASND | ASCENDIS PHARMA ADRsponsored adr | $3,151,092 | -12.2% | 29,400 | 0.0% | 0.88% | -20.7% | |
| ZLAB | Zai Lab Ltd ADR (V1 Ord)adr | $2,626,143 | +8.4% | 78,958 | 0.0% | 0.73% | -2.0% | |
| JAZZ | JAZZ PHARMS. | $2,514,984 | -8.2% | 17,200 | 0.0% | 0.70% | -17.0% | |
| Buy | CARIBOU BIOSCIENCES INC | $2,426,828 | +49.8% | 457,892 | +77.6% | 0.68% | +35.4% | |
| APLS | APELLIS PHARMS. | $2,089,347 | +27.5% | 31,700 | 0.0% | 0.58% | +15.2% | |
| KRTX | New | KARUNA THERAPEUTICS INC | $1,997,160 | – | 11,000 | +100.0% | 0.56% | – |
| DNLI | Buy | DENALI THERAPEUTICS | $1,994,688 | +88.9% | 86,575 | +127.8% | 0.56% | +70.9% |
| NVCR | NOVOCURE LTD | $1,924,480 | -17.9% | 32,000 | 0.0% | 0.54% | -25.8% | |
| LEGN | LEGEND BIOTECHsponsored ads | $1,833,880 | -3.2% | 38,000 | 0.0% | 0.51% | -12.5% | |
| GH | GUARDANT HEALTH | $1,746,280 | -13.7% | 74,500 | 0.0% | 0.49% | -22.1% | |
| HALO | New | HALOZYME THERAPEUTICS INC | $1,736,735 | – | 45,500 | +100.0% | 0.48% | – |
| MIRM | MIRUM PHARMACEUTICALS INC | $1,616,625 | +23.1% | 67,500 | 0.0% | 0.45% | +11.4% | |
| CRSP | CRISPR THERAPEUTICS AGnamen akt | $1,546,524 | +11.2% | 34,200 | 0.0% | 0.43% | +0.7% | |
| IONS | New | IONIS PHARMS. | $1,537,250 | – | 43,000 | +100.0% | 0.43% | – |
| RCKT | ROCKET PHARMS. | $1,079,190 | -12.3% | 63,000 | 0.0% | 0.30% | -20.8% | |
| IMAB | I-MAB-SPONSORED ADRsponsored ads | $1,074,327 | -16.8% | 310,499 | 0.0% | 0.30% | -24.8% | |
| NVAX | NOVAVAX INC | $924,850 | -32.0% | 132,500 | 0.0% | 0.26% | -38.6% | |
| XENE | XENON PHARMACEUTICALS INC | $912,390 | -9.1% | 25,500 | 0.0% | 0.26% | -17.7% | |
| NTLA | INTELLIA THERAPEUTICS | $894,000 | +6.9% | 24,000 | 0.0% | 0.25% | -3.5% | |
| ACET | ADICET BIO INC | $889,571 | -35.5% | 154,708 | 0.0% | 0.25% | -41.8% | |
| HCM | HUTCHMED CHINA LTDsponsored ads | $885,360 | -11.7% | 68,000 | 0.0% | 0.25% | -20.3% | |
| BEAM | BEAM THERAPEUTICS INC | $717,925 | -21.9% | 23,500 | 0.0% | 0.20% | -29.6% | |
| INSM | INSMED INC | $682,101 | -14.8% | 40,100 | 0.0% | 0.19% | -23.1% | |
| IRWD | IRONWOOD PHARMACEUTICALS INC | $631,200 | -15.1% | 60,000 | 0.0% | 0.18% | -23.5% | |
| New | VENTYX BIOSCIENCES INC | $501,450 | – | 15,000 | +100.0% | 0.14% | – | |
| BCRX | BIOCRYST PHARMS. | $475,380 | -27.3% | 57,000 | 0.0% | 0.13% | -34.2% | |
| ARVN | ARVINAS INC | $463,930 | -20.1% | 17,000 | 0.0% | 0.13% | -27.9% | |
| IOVA | IOVANCE BIOTHERAPEUTICS | $341,600 | -4.4% | 56,000 | 0.0% | 0.10% | -13.6% | |
| IDYA | Sell | IDEAYA BIOSCIENCES | $260,870 | -86.8% | 19,000 | -82.6% | 0.07% | -88.1% |
| BLACK DIAMOND THERAPEUTIC | $82,280 | +3.9% | 44,000 | 0.0% | 0.02% | -4.2% | ||
| RLMD | RELMADA THERAPEUTICS | $22,500 | -35.5% | 10,000 | 0.0% | 0.01% | -45.5% | |
| ALLO | Exit | ALLOGENE THERAPEUTICS INC | $0 | – | -50,000 | -100.0% | -0.10% | – |
| FATE | Exit | FATE THERAPEUTICS INC COM | $0 | – | -46,000 | -100.0% | -0.14% | – |
| ALBO | Exit | ALBIREO PHARMA INC COM | $0 | – | -38,000 | -100.0% | -0.25% | – |
| CNCE | Exit | CONCERT PHARMACEUTICALS I | $0 | – | -200,800 | -100.0% | -0.36% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -193,741 | -100.0% | -0.44% | – |
| HZNP | Exit | HORIZON THERAPEUTICS PLC | $0 | – | -314,973 | -100.0% | -11.06% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-05-18
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| GILEAD SCIENCES INC COMMO | 28 | Q3 2023 | 9.3% |
| INCYTE CORP INC COM | 28 | Q3 2023 | 7.9% |
| BIOMARIN PHARMACEUTICALS INC | 28 | Q3 2023 | 7.5% |
| REGENERON PHARMS. | 27 | Q3 2023 | 9.0% |
| BIOGEN INC COMMON STOCK | 26 | Q3 2023 | 8.7% |
| VERTEX PHARMS. | 25 | Q3 2023 | 8.4% |
| AMGEN INC COM | 25 | Q3 2023 | 7.9% |
| NEUROCRINE BIOSCIENCES INC | 25 | Q3 2023 | 6.9% |
| ALYNYLAM PHARMACEUTICALS INC | 25 | Q3 2023 | 6.7% |
| IONIS PHARMS. | 25 | Q3 2023 | 4.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Altus Pharmaceuticals Inc. | February 12, 2009 | ? | ? |
| MICROMET, INC. | February 14, 2008 | 1,907,390 | 4.7% |
| EPIMMUNE INC | February 15, 2005 | 1,279,659 | 8.0% |
| ESSENTIAL THERAPEUTICS INC | April 29, 2003 | 2,500,000 | 11.7% |
| TARGETED GENETICS CORP /WA/ | April 18, 2003 | ? | ? |
| ESSENTIAL THERAPEUTICS INC | November 05, 2001 | 11 | 13.0% |
| ONYX PHARMACEUTICALS INC | October 15, 2001 | 11 | 13.0% |
| CORVAS INTERNATIONAL INC | October 12, 2001 | 11 | 13.0% |
| RIBOZYME PHARMACEUTICALS INC | October 05, 2001 | 11 | 13.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-08 |
| 13F-HR | 2023-05-18 |
| 13F-HR | 2023-02-01 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-16 |
| 13F-HR | 2022-05-20 |
| 13F-HR | 2022-02-15 |
| 13F-HR | 2021-11-12 |
| 13F-HR | 2021-08-11 |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.