$324 Million is the total value of INTERNATIONAL BIOTECHNOLOGY TRUST PLC's 63 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 13.6% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| HZNP | Sell | HORIZON THERAPEUTICS PLC | $35,828,179 | +27.2% | 314,973 | -30.8% | 11.06% | +22.5% |
| SGEN | SEAGEN INC COM | $21,356,700 | -6.1% | 166,200 | 0.0% | 6.60% | -9.5% | |
| INCY | Sell | INCYTE CORP INC COM | $18,390,990 | -4.5% | 229,000 | -20.8% | 5.68% | -8.0% |
| ALKS | ALKERMES PLC SHS | $15,483,230 | +16.9% | 593,000 | 0.0% | 4.78% | +12.6% | |
| HRMY | Harmony Biosciences Holdi | $14,560,725 | +24.3% | 264,500 | 0.0% | 4.50% | +19.7% | |
| QURE | Buy | UNIQURE N.V. COM EUR0.05 | $14,297,160 | +40.0% | 631,500 | +16.0% | 4.42% | +34.9% |
| SUPN | Buy | SUPERNUS PHARMACEUTICALS | $13,671,775 | +35.8% | 383,500 | +28.9% | 4.22% | +30.8% |
| ITCI | INTRA-CELLULAR THERAPIES | $11,733,964 | +13.9% | 221,856 | 0.0% | 3.62% | +9.7% | |
| MRTX | Buy | MIRATI THERAPEUTICS INC C | $11,055,640 | +16.4% | 244,000 | +79.4% | 3.42% | +12.1% |
| ILMN | Buy | ILLUMINA INC COM | $9,396,720 | +97.2% | 46,500 | +86.0% | 2.90% | +89.9% |
| ALNY | ALNYLAM PHARMACEUTICALS I | $9,018,160 | +18.7% | 38,000 | 0.0% | 2.78% | +14.3% | |
| KDNY | CHINOOK THERAPEUTICS INC | $8,914,788 | +33.4% | 340,389 | 0.0% | 2.75% | +28.4% | |
| EXEL | EXELIXIS INC COM | $8,709,720 | +2.4% | 543,000 | 0.0% | 2.69% | -1.4% | |
| REGN | REGENERON PHARMACEUTICALS | $8,080,128 | +4.7% | 11,200 | 0.0% | 2.50% | +0.9% | |
| RARE | ULTRAGENYX PHARMACEUTICAL | $8,060,348 | +12.0% | 174,052 | 0.0% | 2.49% | +7.8% | |
| TVTX | Buy | TRAVERE THERAPEUTICS INC | $7,963,189 | +73.8% | 379,019 | +103.8% | 2.46% | +67.4% |
| DYN | Buy | DYNE THERAPEUTICS INC COM | $7,417,157 | +67.1% | 641,068 | +83.1% | 2.29% | +61.0% |
| SNY | SANOFIsponsored adr | $6,942,530 | +27.2% | 143,500 | 0.0% | 2.14% | +22.5% | |
| BIIB | Sell | BIOGEN INC COMMON STOCK | $5,923,520 | -51.2% | 21,400 | -53.0% | 1.83% | -53.1% |
| PTCT | Buy | PTC THERAPEUTICS INC COM | $5,493,600 | +420.7% | 144,000 | +585.7% | 1.70% | +402.1% |
| VERA | VERA THERAPEUTICScl a | $5,428,260 | -9.4% | 281,257 | 0.0% | 1.68% | -12.7% | |
| GILD | Sell | GILEAD SCIENCES INC COMMO | $4,942,435 | -61.6% | 57,584 | -72.4% | 1.53% | -63.1% |
| BMRN | Sell | BIOMARIN PHARMACEUTICAL I | $4,514,467 | -9.2% | 43,656 | -25.6% | 1.39% | -12.5% |
| AZN | New | ASTRAZENECA PLC SPONSOREDsponsored adr | $4,406,350 | – | 65,000 | +100.0% | 1.36% | – |
| AMGN | AMGEN INC COM | $4,265,225 | +16.5% | 16,246 | 0.0% | 1.32% | +12.2% | |
| UTHR | UNITED THERAPEUTICS CORP | $4,171,200 | +32.9% | 15,000 | 0.0% | 1.29% | +27.9% | |
| ASND | ASCENDIS PHARMA A/S SPONSsponsored adr | $3,588,270 | +18.2% | 29,400 | 0.0% | 1.11% | +13.8% | |
| KRYS | KRYSTAL BIOTECH INC COM | $3,558,150 | +13.6% | 45,000 | 0.0% | 1.10% | +9.5% | |
| BGNE | BEIGENE LTD SPONSORED ADRsponsored adr | $3,452,116 | +63.1% | 15,700 | 0.0% | 1.07% | +57.0% | |
| JAZZ | JAZZ PHARMACEUTICALS PLC | $2,739,444 | +19.6% | 17,200 | 0.0% | 0.85% | +15.1% | |
| AUPH | AURINIA PHARMACEUTICALS I | $2,477,650 | -42.6% | 573,530 | 0.0% | 0.76% | -44.7% | |
| ZLAB | ZAI LAB LTD ADRadr | $2,423,221 | -10.0% | 78,958 | 0.0% | 0.75% | -13.3% | |
| NVCR | Novocure Ltd | $2,344,000 | -3.6% | 32,000 | 0.0% | 0.72% | -7.2% | |
| RVNC | REVANCE THERAPEUTICS INC | $2,214,000 | -31.7% | 120,000 | 0.0% | 0.68% | -34.2% | |
| GH | GUARDANT HEALTH INC COM | $2,024,165 | -49.4% | 74,500 | 0.0% | 0.62% | -51.3% | |
| IDYA | IDEAYA BIOSCIENCES INC CO | $1,980,530 | +21.9% | 109,000 | 0.0% | 0.61% | +17.5% | |
| LEGN | Legend Biotech Corpsponsored ads | $1,894,300 | +22.1% | 38,000 | 0.0% | 0.58% | +17.7% | |
| APLS | New | APELLIS PHARMACEUTICALS I | $1,638,256 | – | 31,700 | +100.0% | 0.51% | – |
| CARIBOU BIOSCIENCES INC C | $1,619,562 | -40.4% | 257,892 | 0.0% | 0.50% | -42.6% | ||
| ACAD | New | ACADIA PHARMACEUTICALS IN | $1,590,000 | – | 100,000 | +100.0% | 0.49% | – |
| FULC | FULCRUM THERAPEUTICS INC | $1,408,497 | -9.9% | 193,741 | 0.0% | 0.44% | -13.2% | |
| CRSP | CRISPR THERAPEUTICS AG COnamen akt | $1,390,230 | -37.8% | 34,200 | 0.0% | 0.43% | -40.2% | |
| ACET | ADICET BIO INC COM | $1,379,995 | -37.1% | 154,708 | 0.0% | 0.43% | -39.5% | |
| NVAX | NOVAVAX INC | $1,360,775 | -43.6% | 132,500 | 0.0% | 0.42% | -45.7% | |
| MIRM | Buy | MIRUM PHARMACEUTICALS INC | $1,312,875 | +580.2% | 67,500 | +632.2% | 0.40% | +553.2% |
| IMAB | Sell | I-MAB SPONSORED ADSsponsored ads | $1,291,676 | -36.2% | 310,499 | -38.8% | 0.40% | -38.5% |
| RCKT | ROCKET PHARMACEUTICALS IN | $1,231,020 | +22.5% | 63,000 | 0.0% | 0.38% | +18.0% | |
| CNCE | CONCERT PHARMACEUTICALS I | $1,172,672 | -12.8% | 200,800 | 0.0% | 0.36% | -16.0% | |
| DNLI | DENALI THERAPEUTICS INC C | $1,056,020 | -9.4% | 38,000 | 0.0% | 0.33% | -12.8% | |
| HCM | HUTCHMED CHINA LIMITED SPsponsored ads | $1,003,000 | +66.6% | 68,000 | 0.0% | 0.31% | +60.6% | |
| XENE | XENON PHARMACEUTICALS INC | $1,003,425 | +9.3% | 25,500 | 0.0% | 0.31% | +5.4% | |
| BEAM | BEAM THERAPEUTICS INC COM | $919,085 | -17.9% | 23,500 | 0.0% | 0.28% | -20.9% | |
| NTLA | INTELLIA THERAPEUTICS INC | $836,640 | -37.7% | 24,000 | 0.0% | 0.26% | -40.1% | |
| ALBO | Buy | ALBIREO PHARMA INC COM | $820,420 | +163.0% | 38,000 | +136.1% | 0.25% | +153.0% |
| INSM | INSMED INC COM PAR $.01 | $800,396 | -7.4% | 40,100 | 0.0% | 0.25% | -10.8% | |
| IRWD | IRONWOOD PHARMACEUTICALS | $743,400 | +19.7% | 60,000 | 0.0% | 0.23% | +15.6% | |
| BCRX | BIOCRYST PHARMACEUTICALS | $653,790 | -8.9% | 57,000 | 0.0% | 0.20% | -12.2% | |
| ARVN | ARVINAS INC COM | $580,550 | -23.2% | 17,000 | 0.0% | 0.18% | -26.0% | |
| FATE | Sell | FATE THERAPEUTICS INC COM | $463,680 | -82.9% | 46,000 | -62.0% | 0.14% | -83.6% |
| IOVA | IOVANCE BIOTHERAPEUTICS I | $357,280 | -33.3% | 56,000 | 0.0% | 0.11% | -36.0% | |
| ALLO | ALLOGENE THERAPEUTICS INC | $314,000 | -41.7% | 50,000 | 0.0% | 0.10% | -43.9% | |
| BLACK DIAMOND THERAPEUTIC | $79,200 | +5.6% | 44,000 | 0.0% | 0.02% | 0.0% | ||
| RLMD | RELMADA THERAPEUTICS INC | $34,900 | -90.6% | 10,000 | 0.0% | 0.01% | -90.8% | |
| MDGL | Exit | MADRIGAL PHARMS. | $0 | – | -5,350 | -100.0% | -0.11% | – |
| AXSM | Exit | AXSOME THERAPEUTICS | $0 | – | -14,000 | -100.0% | -0.20% | – |
| VTRS | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -364,000 | -100.0% | -0.99% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES | $0 | – | -30,000 | -100.0% | -1.02% | – |
| KALV | Exit | KALVISTA PHARMS. | $0 | – | -316,133 | -100.0% | -1.47% | – |
| GLPG | Exit | GALAPAGOS NVsponsored adr | $0 | – | -123,300 | -100.0% | -1.68% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-01
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| GILEAD SCIENCES INC COMMO | 28 | Q3 2023 | 9.3% |
| INCYTE CORP INC COM | 28 | Q3 2023 | 7.9% |
| BIOMARIN PHARMACEUTICALS INC | 28 | Q3 2023 | 7.5% |
| REGENERON PHARMS. | 27 | Q3 2023 | 9.0% |
| BIOGEN INC COMMON STOCK | 26 | Q3 2023 | 8.7% |
| VERTEX PHARMS. | 25 | Q3 2023 | 8.4% |
| AMGEN INC COM | 25 | Q3 2023 | 7.9% |
| NEUROCRINE BIOSCIENCES INC | 25 | Q3 2023 | 6.9% |
| ALYNYLAM PHARMACEUTICALS INC | 25 | Q3 2023 | 6.7% |
| IONIS PHARMS. | 25 | Q3 2023 | 4.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Altus Pharmaceuticals Inc. | February 12, 2009 | ? | ? |
| MICROMET, INC. | February 14, 2008 | 1,907,390 | 4.7% |
| EPIMMUNE INC | February 15, 2005 | 1,279,659 | 8.0% |
| ESSENTIAL THERAPEUTICS INC | April 29, 2003 | 2,500,000 | 11.7% |
| TARGETED GENETICS CORP /WA/ | April 18, 2003 | ? | ? |
| ESSENTIAL THERAPEUTICS INC | November 05, 2001 | 11 | 13.0% |
| ONYX PHARMACEUTICALS INC | October 15, 2001 | 11 | 13.0% |
| CORVAS INTERNATIONAL INC | October 12, 2001 | 11 | 13.0% |
| RIBOZYME PHARMACEUTICALS INC | October 05, 2001 | 11 | 13.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-08 |
| 13F-HR | 2023-05-18 |
| 13F-HR | 2023-02-01 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-16 |
| 13F-HR | 2022-05-20 |
| 13F-HR | 2022-02-15 |
| 13F-HR | 2021-11-12 |
| 13F-HR | 2021-08-11 |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.