$329 Million is the total value of INTERNATIONAL BIOTECHNOLOGY TRUST PLC's 61 reported holdings in Q2 2023. The portfolio turnover from Q1 2023 to Q2 2023 was 45.3% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| AMGN | Buy | AMGEN INC COM | $26,025,095 | +18.0% | 117,246 | +28.5% | 7.92% | +28.8% |
| INCY | Buy | INCYTE CORP | $22,303,008 | +10.6% | 358,454 | +28.5% | 6.79% | +20.7% |
| HRMY | HARMONY BIOSCIENCES HLDGS | $20,070,190 | +7.8% | 570,500 | 0.0% | 6.11% | +17.6% | |
| REGN | Buy | REGENERON PHARMS. | $19,400,040 | +110.9% | 27,000 | +141.1% | 5.91% | +130.2% |
| SUPN | Buy | SUPERNUS PHARMS. | $15,736,410 | +2.7% | 523,500 | +23.6% | 4.79% | +12.0% |
| VERA | Sell | VERA THERAPEUTICScl a | $15,642,641 | +101.9% | 975,227 | -2.7% | 4.76% | +120.3% |
| ALNY | Buy | ALNYLAM PHARMS. | $15,499,104 | +66.1% | 81,600 | +75.1% | 4.72% | +81.2% |
| APLS | Buy | APELLIS PHARMS. | $11,810,482 | +465.3% | 129,700 | +309.1% | 3.60% | +516.6% |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $11,647,077 | +82.6% | 52,759 | +85.1% | 3.55% | +99.2% |
| ITCI | Sell | INTRA-CELLULAR THERAPIES | $11,182,605 | -19.9% | 176,856 | -31.4% | 3.40% | -12.6% |
| GILD | Buy | GILEAD SCIENCES | $11,137,306 | +133.1% | 144,584 | +151.1% | 3.39% | +154.3% |
| ILMN | Buy | ILLUMINA INC | $9,463,195 | +53.6% | 50,500 | +90.6% | 2.88% | +67.6% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $9,393,800 | +3.5% | 260,000 | +6.6% | 2.86% | +13.0% |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $7,386,750 | -28.9% | 21,000 | -36.4% | 2.25% | -22.4% |
| RVNC | Buy | REVANCE THERAPEUTICS INC | $7,298,993 | +23.9% | 288,726 | +57.8% | 2.22% | +35.2% |
| HZNP | New | HORIZON THERAPEUTICS | $6,890,950 | – | 67,000 | +100.0% | 2.10% | – |
| TVTX | Buy | TRAVERE THERAPEUTICS INC | $6,769,642 | +113.5% | 441,019 | +212.7% | 2.06% | +132.9% |
| NBIX | New | NEUROCRINE BIOSCIENCES | $6,490,280 | – | 68,877 | +100.0% | 1.98% | – |
| KRTX | Buy | KARUNA THERAPEUTICS INC | $5,566,620 | +178.7% | 25,700 | +133.6% | 1.70% | +204.3% |
| AUPH | AURINIA PHARMACEUTICALS INC | $5,551,770 | -11.6% | 573,530 | 0.0% | 1.69% | -3.5% | |
| DNLI | Buy | DENALI THERAPEUTICS | $5,538,480 | +177.7% | 188,000 | +117.2% | 1.69% | +202.7% |
| KRYS | Sell | KRYSTAL BIOTECH | $5,389,349 | +10.4% | 45,945 | -24.7% | 1.64% | +20.4% |
| BMRN | BIOMARIN PHARM. | $5,083,129 | -10.9% | 58,656 | 0.0% | 1.55% | -2.8% | |
| MDGL | New | MADRIGAL PHARMS. | $4,227,300 | – | 18,300 | +100.0% | 1.29% | – |
| AXSM | New | AXSOME THERAPEUTICS | $4,185,940 | – | 58,300 | +100.0% | 1.27% | – |
| ERASCA INC | $3,921,500 | -8.3% | 1,426,000 | 0.0% | 1.19% | 0.0% | ||
| RARE | Sell | ULTRAGENYX PHARM. | $3,691,198 | -65.1% | 80,052 | -69.7% | 1.12% | -61.9% |
| AKRO | New | AKERO THERAPEUTICS INC | $3,662,297 | – | 78,489 | +100.0% | 1.12% | – |
| ACAD | Sell | ACADIA PHARMACEUTICALS IN | $3,616,450 | -10.9% | 151,000 | -30.1% | 1.10% | -2.8% |
| HALO | Buy | HALOZYME THERAPEUTICS INC | $3,443,730 | +98.3% | 95,500 | +109.9% | 1.05% | +116.1% |
| DYN | Sell | DYNE THERAPEUTICS | $3,383,449 | -32.2% | 300,751 | -30.7% | 1.03% | -26.0% |
| BIIB | Sell | BIOGEN INC | $3,132,690 | -47.3% | 11,000 | -48.6% | 0.95% | -42.5% |
| RCKT | Buy | ROCKET PHARMS. | $3,093,480 | +186.6% | 156,000 | +147.6% | 0.94% | +213.0% |
| LEGN | LEGEND BIOTECHsponsored ads | $2,623,140 | +43.0% | 38,000 | 0.0% | 0.80% | +56.1% | |
| ZLAB | Zai Lab Ltd ADR (V1 Ord)adr | $2,189,505 | -16.6% | 78,958 | 0.0% | 0.67% | -9.0% | |
| SRPT | New | SAREPTA THERAPEUTICS INC | $2,152,976 | – | 18,800 | +100.0% | 0.66% | – |
| JAZZ | JAZZ PHARMS. | $2,131,768 | -15.2% | 17,200 | 0.0% | 0.65% | -7.5% | |
| IONS | IONIS PHARMS. | $1,763,860 | +14.7% | 43,000 | 0.0% | 0.54% | +25.2% | |
| MIRM | MIRUM PHARMACEUTICALS INC | $1,742,850 | +7.8% | 67,500 | 0.0% | 0.53% | +17.7% | |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $1,630,075 | – | 48,099 | +100.0% | 0.50% | – |
| BGNE | Sell | BEIGENE ADRsponsored adr | $1,548,339 | -68.4% | 8,700 | -61.7% | 0.47% | -65.5% |
| NVCR | NOVOCURE LTD | $1,327,680 | -31.0% | 32,000 | 0.0% | 0.40% | -24.8% | |
| GH | Sell | GUARDANT HEALTH | $1,305,605 | -25.2% | 36,500 | -51.0% | 0.40% | -18.5% |
| CYTK | New | CYTOKINETICS INC | $1,205,830 | – | 37,000 | +100.0% | 0.37% | – |
| XENE | XENON PHARMACEUTICALS INC | $981,750 | +7.6% | 25,500 | 0.0% | 0.30% | +17.3% | |
| New | MARINUS PHARMACEUTICALS INC | $977,400 | – | 90,000 | +100.0% | 0.30% | – | |
| NTLA | INTELLIA THERAPEUTICS | $977,760 | +9.4% | 24,000 | 0.0% | 0.30% | +19.7% | |
| SAGE | New | SAGE THERAPEUTICS INC | $939,400 | – | 20,000 | +100.0% | 0.29% | – |
| IMAB | I-MAB-SPONSORED ADRsponsored ads | $925,287 | -13.9% | 310,499 | 0.0% | 0.28% | -6.0% | |
| INSM | INSMED INC | $845,308 | +23.9% | 40,100 | 0.0% | 0.26% | +35.3% | |
| HCM | HUTCHMED CHINA LTDsponsored ads | $816,000 | -7.8% | 68,000 | 0.0% | 0.25% | +0.4% | |
| BEAM | BEAM THERAPEUTICS INC | $750,355 | +4.5% | 23,500 | 0.0% | 0.23% | +14.0% | |
| PTCT | Sell | PTC THERAPEUTICS | $691,730 | -84.6% | 17,000 | -81.7% | 0.21% | -83.2% |
| AGIO | New | AGIOS PHARMS. | $679,680 | – | 24,000 | +100.0% | 0.21% | – |
| PTGX | New | PROTAGONIST THERAPEUTICS INC | $549,240 | – | 19,900 | +100.0% | 0.17% | – |
| New | AMYLYX PHARMACEUTICALS INC | $538,500 | – | 25,000 | +100.0% | 0.16% | – | |
| VENTYX BIOSCIENCES INC | $491,400 | -2.0% | 15,000 | 0.0% | 0.15% | +7.1% | ||
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS | $456,950 | +33.8% | 65,000 | +16.1% | 0.14% | +46.3% |
| ARVN | ARVINAS INC | $421,090 | -9.2% | 17,000 | 0.0% | 0.13% | -0.8% | |
| QURE | Sell | UNIQURE NV | $177,630 | -98.2% | 15,500 | -96.8% | 0.05% | -98.0% |
| RLMD | RELMADA THERAPEUTICS | $24,700 | +9.8% | 10,000 | 0.0% | 0.01% | +33.3% | |
| Exit | BLACK DIAMOND THERAPEUTIC | $0 | – | -44,000 | -100.0% | -0.02% | – | |
| IDYA | Exit | IDEAYA BIOSCIENCES | $0 | – | -19,000 | -100.0% | -0.07% | – |
| BCRX | Exit | BIOCRYST PHARMS. | $0 | – | -57,000 | -100.0% | -0.13% | – |
| IRWD | Exit | IRONWOOD PHARMACEUTICALS INC | $0 | – | -60,000 | -100.0% | -0.18% | – |
| ACET | Exit | ADICET BIO INC | $0 | – | -154,708 | -100.0% | -0.25% | – |
| NVAX | Exit | NOVAVAX INC | $0 | – | -132,500 | -100.0% | -0.26% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -34,200 | -100.0% | -0.43% | – |
| Exit | CARIBOU BIOSCIENCES INC | $0 | – | -457,892 | -100.0% | -0.68% | – | |
| ASND | Exit | ASCENDIS PHARMA ADRsponsored adr | $0 | – | -29,400 | -100.0% | -0.88% | – |
| GMAB | Exit | GENMAB A/Ssponsored ads | $0 | – | -88,000 | -100.0% | -0.93% | – |
| AZN | Exit | ASTRAZENECA PLC SPONSOREDsponsored adr | $0 | – | -65,000 | -100.0% | -1.26% | – |
| KDNY | Exit | CHINOOK THERAPEUTICS | $0 | – | -319,989 | -100.0% | -2.07% | – |
| SNY | Exit | SANOFIsponsored adr | $0 | – | -143,500 | -100.0% | -2.18% | – |
| EXEL | Exit | EXELIXIS INC | $0 | – | -543,000 | -100.0% | -2.94% | – |
| ALKS | Exit | ALKERMES PLC | $0 | – | -593,000 | -100.0% | -4.66% | – |
| SGEN | Exit | SEAGEN INC | $0 | – | -200,200 | -100.0% | -11.30% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-08-08
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| GILEAD SCIENCES INC COMMO | 28 | Q3 2023 | 9.3% |
| INCYTE CORP INC COM | 28 | Q3 2023 | 7.9% |
| BIOMARIN PHARMACEUTICALS INC | 28 | Q3 2023 | 7.5% |
| REGENERON PHARMS. | 27 | Q3 2023 | 9.0% |
| BIOGEN INC COMMON STOCK | 26 | Q3 2023 | 8.7% |
| VERTEX PHARMS. | 25 | Q3 2023 | 8.4% |
| AMGEN INC COM | 25 | Q3 2023 | 7.9% |
| NEUROCRINE BIOSCIENCES INC | 25 | Q3 2023 | 6.9% |
| ALYNYLAM PHARMACEUTICALS INC | 25 | Q3 2023 | 6.7% |
| IONIS PHARMS. | 25 | Q3 2023 | 4.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Altus Pharmaceuticals Inc. | February 12, 2009 | ? | ? |
| MICROMET, INC. | February 14, 2008 | 1,907,390 | 4.7% |
| EPIMMUNE INC | February 15, 2005 | 1,279,659 | 8.0% |
| ESSENTIAL THERAPEUTICS INC | April 29, 2003 | 2,500,000 | 11.7% |
| TARGETED GENETICS CORP /WA/ | April 18, 2003 | ? | ? |
| ESSENTIAL THERAPEUTICS INC | November 05, 2001 | 11 | 13.0% |
| ONYX PHARMACEUTICALS INC | October 15, 2001 | 11 | 13.0% |
| CORVAS INTERNATIONAL INC | October 12, 2001 | 11 | 13.0% |
| RIBOZYME PHARMACEUTICALS INC | October 05, 2001 | 11 | 13.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-08 |
| 13F-HR | 2023-05-18 |
| 13F-HR | 2023-02-01 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-16 |
| 13F-HR | 2022-05-20 |
| 13F-HR | 2022-02-15 |
| 13F-HR | 2021-11-12 |
| 13F-HR | 2021-08-11 |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.