$312 Million is the total value of INTERNATIONAL BIOTECHNOLOGY TRUST PLC's 66 reported holdings in Q3 2022. The portfolio turnover from Q2 2022 to Q3 2022 was 30.8% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| HZNP | Buy | HORIZON THERAPEUTICS | $28,158,000 | -90.2% | 454,973 | +1885.5% | 9.03% | +201.6% |
| SGEN | Buy | SEAGEN INC | $22,739,000 | -65.3% | 166,200 | +1331.9% | 7.29% | +965.9% |
| INCY | Buy | INCYTE CORP | $19,253,000 | -91.9% | 289,000 | +1498.4% | 6.17% | +148.7% |
| ALKS | Buy | ALKERMES PLC | $13,248,000 | -74.0% | 593,000 | +38938.8% | 4.25% | +698.5% |
| GILD | Buy | GILEAD SCIENCES | $12,880,000 | -91.2% | 208,784 | +2216.7% | 4.13% | +171.5% |
| BIIB | Buy | BIOGEN INC | $12,149,000 | -76.6% | 45,500 | +329.0% | 3.90% | +618.8% |
| HRMY | Buy | HARMONY BIOSCIENCES HLDGS | $11,715,000 | -94.7% | 264,500 | +2350.4% | 3.76% | +62.6% |
| ITCI | Buy | INTRA-CELLULAR THERAPIES | $10,303,000 | -83.7% | 221,856 | +6057.5% | 3.30% | +401.4% |
| QURE | Buy | UNIQURE NV | $10,209,000 | -97.7% | 544,500 | +6446.0% | 3.27% | -29.7% |
| SUPN | Buy | SUPERNUS PHARMS. | $10,070,000 | -96.6% | 297,500 | +3357.7% | 3.23% | +4.1% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $9,498,000 | -93.0% | 136,000 | +1389.4% | 3.05% | +114.7% |
| EXEL | Buy | EXELIXIS INC | $8,509,000 | -97.6% | 543,000 | +7348.6% | 2.73% | -25.3% |
| REGN | Sell | REGENERON PHARMS. | $7,715,000 | -67.4% | 11,200 | -20.1% | 2.47% | +901.6% |
| ALNY | Buy | ALNYLAM PHARMS. | $7,597,000 | -80.0% | 38,000 | +585.7% | 2.44% | +515.2% |
| RARE | Buy | ULTRAGENYX PHARM. | $7,197,000 | -95.5% | 174,052 | +1711.2% | 2.31% | +37.4% |
| KDNY | Buy | CHINOOK THERAPEUTICS | $6,685,000 | -98.0% | 340,389 | +5623.7% | 2.14% | -39.6% |
| VERA | Buy | VERA THERAPEUTICScl a | $5,994,000 | -97.9% | 281,257 | +7253.1% | 1.92% | -34.4% |
| SNY | Buy | SANOFIsponsored adr | $5,456,000 | -82.7% | 143,500 | +9005.3% | 1.75% | +431.9% |
| GLPG | Buy | GALAPAGOS NVsponsored adr | $5,251,000 | -95.7% | 123,300 | +1693.2% | 1.68% | +30.9% |
| BMRN | Buy | BIOMARIN PHARM. | $4,971,000 | -93.8% | 58,656 | +788.6% | 1.59% | +91.8% |
| ILMN | Buy | ILLUMINA INC | $4,766,000 | -90.1% | 25,000 | +182.5% | 1.53% | +205.0% |
| KALV | Buy | KALVISTA PHARMS. | $4,587,000 | -98.8% | 316,133 | +8307.8% | 1.47% | -63.2% |
| TVTX | Buy | TRAVERE THERAPEUTICS INC | $4,582,000 | -98.8% | 186,019 | +1918.7% | 1.47% | -62.9% |
| DYN | Buy | DYNE THERAPEUTICS | $4,439,000 | -99.2% | 350,068 | +8957.4% | 1.42% | -75.7% |
| AUPH | Buy | AURINIA PHARMACEUTICALS INC | $4,313,000 | -99.2% | 573,530 | +9860.6% | 1.38% | -76.9% |
| GH | Buy | GUARDANT HEALTH | $4,004,000 | -94.6% | 74,500 | +2379.2% | 1.28% | +65.3% |
| AMGN | Buy | AMGEN INC COM | $3,662,000 | -91.0% | 16,246 | +63.9% | 1.17% | +176.2% |
| RVNC | New | REVANCE THERAPEUTICS INC | $3,240,000 | – | 120,000 | +100.0% | 1.04% | – |
| NBIX | Buy | NEUROCRINE BIOSCIENCES | $3,185,000 | -98.7% | 30,000 | +30.4% | 1.02% | -58.5% |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $3,139,000 | -84.3% | 15,000 | +218.3% | 1.01% | +381.8% |
| KRYS | Buy | KRYSTAL BIOTECH | $3,132,000 | -93.0% | 45,000 | +1422.8% | 1.00% | +114.1% |
| VTRS | New | UNITED THERAPEUTICS CORP DEL | $3,101,000 | – | 364,000 | +100.0% | 0.99% | – |
| ASND | Buy | ASCENDIS PHARMA ADRsponsored adr | $3,036,000 | -89.7% | 29,400 | +975.7% | 0.97% | +217.3% |
| Buy | CARIBOU BIOSCIENCES INC | $2,716,000 | -98.9% | 257,892 | +18614.9% | 0.87% | -67.2% | |
| FATE | Buy | FATE THERAPEUTICS | $2,712,000 | -98.3% | 121,000 | +2989.1% | 0.87% | -47.2% |
| ZLAB | Buy | Zai Lab Ltd ADR (V1 Ord)adr | $2,692,000 | -96.6% | 78,958 | +2785.9% | 0.86% | +4.7% |
| NVCR | Buy | NOVOCURE LTD | $2,431,000 | -92.4% | 32,000 | +1338.8% | 0.78% | +133.5% |
| NVAX | Buy | NOVAVAX INC | $2,414,000 | -98.2% | 132,500 | +1844.5% | 0.77% | -44.0% |
| JAZZ | Buy | JAZZ PHARMS. | $2,291,000 | -86.7% | 17,200 | +541.1% | 0.74% | +310.6% |
| CRSP | Buy | CRISPR THERAPEUTICS AGnamen akt | $2,235,000 | -93.5% | 34,200 | +1545.8% | 0.72% | +100.8% |
| ACET | New | ADICET BIO INC | $2,195,000 | – | 154,708 | +100.0% | 0.70% | – |
| BGNE | Buy | BEIGENE ADRsponsored adr | $2,117,000 | -86.5% | 15,700 | +517.6% | 0.68% | +314.0% |
| IMAB | Buy | I-MAB-SPONSORED ADRsponsored ads | $2,024,000 | -99.6% | 507,239 | +8039.3% | 0.65% | -88.8% |
| IDYA | Buy | IDEAYA BIOSCIENCES | $1,625,000 | -98.5% | 109,000 | +7161.8% | 0.52% | -54.2% |
| FULC | Buy | FULCRUM THERAPEUTICS INC | $1,563,000 | -99.2% | 193,741 | +20315.3% | 0.50% | -75.2% |
| LEGN | Buy | LEGEND BIOTECHsponsored ads | $1,551,000 | -65.5% | 38,000 | +15222.6% | 0.50% | +957.4% |
| CNCE | Buy | CONCERT PHARMACEUTICALS INC | $1,345,000 | -99.8% | 200,800 | +7593.5% | 0.43% | -93.3% |
| NTLA | Buy | INTELLIA THERAPEUTICS | $1,343,000 | -94.4% | 24,000 | +1832.4% | 0.43% | +72.4% |
| DNLI | Buy | DENALI THERAPEUTICS | $1,166,000 | -96.9% | 38,000 | +3298.9% | 0.37% | -5.6% |
| BEAM | Buy | BEAM THERAPEUTICS INC | $1,119,000 | -95.2% | 23,500 | +2482.4% | 0.36% | +46.5% |
| PTCT | Buy | PTC THERAPEUTICS | $1,055,000 | -95.0% | 21,000 | +2394.1% | 0.34% | +54.3% |
| RCKT | Buy | ROCKET PHARMS. | $1,005,000 | -98.4% | 63,000 | +7158.1% | 0.32% | -51.0% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $918,000 | -96.4% | 25,500 | +3194.6% | 0.29% | +10.5% |
| INSM | Buy | INSMED INC | $864,000 | -97.8% | 40,100 | +4969.5% | 0.28% | -33.7% |
| ARVN | New | ARVINAS INC | $756,000 | – | 17,000 | +100.0% | 0.24% | – |
| BCRX | Buy | BIOCRYST PHARMS. | $718,000 | -98.7% | 57,000 | +9368.4% | 0.23% | -61.3% |
| AXSM | Buy | AXSOME THERAPEUTICS | $625,000 | -95.5% | 14,000 | +2516.8% | 0.20% | +37.0% |
| IRWD | Buy | IRONWOOD PHARMACEUTICALS INC | $621,000 | -99.0% | 60,000 | +8570.5% | 0.20% | -68.2% |
| HCM | Buy | HUTCHMED CHINA LTDsponsored ads | $602,000 | -99.1% | 68,000 | +7816.2% | 0.19% | -72.8% |
| ALLO | Buy | ALLOGENE THERAPEUTICS | $539,000 | -98.9% | 50,000 | +8671.9% | 0.17% | -66.9% |
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS | $536,000 | -99.8% | 56,000 | +1759.8% | 0.17% | -94.0% |
| RLMD | Buy | RELMADA THERAPEUTICS | $370,000 | -96.3% | 10,000 | +5163.2% | 0.12% | +14.4% |
| MDGL | Buy | MADRIGAL PHARMS. | $348,000 | -93.5% | 5,350 | +1296.9% | 0.11% | +100.0% |
| ALBO | New | ALBIREO PHARMA INC | $312,000 | – | 16,093 | +100.0% | 0.10% | – |
| MIRM | New | MIRUM PHARMACEUTICALS INC | $193,000 | – | 9,219 | +100.0% | 0.06% | – |
| Buy | BLACK DIAMOND THERAPEUTIC | $75,000 | -99.8% | 44,000 | +41021.5% | 0.02% | -94.8% | |
| Exit | 2SEVENTY BIO INC COM | $0 | – | -48 | -100.0% | -0.04% | – | |
| ANAB | Exit | ANAPTYSBIO INC COM | $0 | – | -203 | -100.0% | -0.10% | – |
| KRTX | Exit | KARUNA THERAPEUTICS INC C | $0 | – | -1,567 | -100.0% | -0.13% | – |
| PRTA | Exit | PROTHENA CORP PLC USD0.01 | $0 | – | -407 | -100.0% | -0.16% | – |
| PTGX | Exit | PROTAGONIST THERAPEUTICS | $0 | – | -128 | -100.0% | -0.17% | – |
| SWTX | Exit | SPRINGWORKS THERAPEUTICS | $0 | – | -401 | -100.0% | -0.17% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -985 | -100.0% | -0.20% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -476 | -100.0% | -0.22% | – |
| BNTX | Exit | BIONTECH SE ADSsponsored ads | $0 | – | -3,847 | -100.0% | -0.27% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS | $0 | – | -441 | -100.0% | -0.33% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS I | $0 | – | -1,470 | -100.0% | -0.34% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -1,703 | -100.0% | -0.48% | – |
| AVDL | Exit | AVADEL PHARMACEUTICALS PLsponsored adr | $0 | – | -122 | -100.0% | -0.52% | – |
| GMAB | Exit | GENMAB -SP ADRsponsored ads | $0 | – | -1,857 | -100.0% | -0.60% | – |
| IMVT | Exit | IMMUNOVANT INC COM | $0 | – | -233 | -100.0% | -0.63% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC C | $0 | – | -1,017 | -100.0% | -0.99% | – |
| GMDA | Exit | GAMIDA CELL | $0 | – | -187 | -100.0% | -1.12% | – |
| CCXI | Exit | CHEMOCENTRYX INC COM STK | $0 | – | -3,000 | -100.0% | -1.26% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-11-08
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| GILEAD SCIENCES INC COMMO | 28 | Q3 2023 | 9.3% |
| INCYTE CORP INC COM | 28 | Q3 2023 | 7.9% |
| BIOMARIN PHARMACEUTICALS INC | 28 | Q3 2023 | 7.5% |
| REGENERON PHARMS. | 27 | Q3 2023 | 9.0% |
| BIOGEN INC COMMON STOCK | 26 | Q3 2023 | 8.7% |
| VERTEX PHARMS. | 25 | Q3 2023 | 8.4% |
| AMGEN INC COM | 25 | Q3 2023 | 7.9% |
| NEUROCRINE BIOSCIENCES INC | 25 | Q3 2023 | 6.9% |
| ALYNYLAM PHARMACEUTICALS INC | 25 | Q3 2023 | 6.7% |
| IONIS PHARMS. | 25 | Q3 2023 | 4.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Altus Pharmaceuticals Inc. | February 12, 2009 | ? | ? |
| MICROMET, INC. | February 14, 2008 | 1,907,390 | 4.7% |
| EPIMMUNE INC | February 15, 2005 | 1,279,659 | 8.0% |
| ESSENTIAL THERAPEUTICS INC | April 29, 2003 | 2,500,000 | 11.7% |
| TARGETED GENETICS CORP /WA/ | April 18, 2003 | ? | ? |
| ESSENTIAL THERAPEUTICS INC | November 05, 2001 | 11 | 13.0% |
| ONYX PHARMACEUTICALS INC | October 15, 2001 | 11 | 13.0% |
| CORVAS INTERNATIONAL INC | October 12, 2001 | 11 | 13.0% |
| RIBOZYME PHARMACEUTICALS INC | October 05, 2001 | 11 | 13.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-08 |
| 13F-HR | 2023-05-18 |
| 13F-HR | 2023-02-01 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-16 |
| 13F-HR | 2022-05-20 |
| 13F-HR | 2022-02-15 |
| 13F-HR | 2021-11-12 |
| 13F-HR | 2021-08-11 |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.