$9.59 Billion is the total value of INTERNATIONAL BIOTECHNOLOGY TRUST PLC's 78 reported holdings in Q2 2022. The portfolio turnover from Q1 2022 to Q2 2022 was 31.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CNCE | New | CONCERT PHARMACEUTICALS I | $620,000,000 | – | 2,610 | +100.0% | 6.47% | – |
| AUPH | Sell | AURINIA PHARMACEUTICALS I | $573,530,000 | +14401.4% | 5,758 | -98.7% | 5.98% | +570.7% |
| DYN | Sell | DYNE THERAPEUTICS INC COM | $562,568,000 | +48481.0% | 3,865 | -99.2% | 5.87% | +2148.3% |
| IMAB | Sell | I-MAB SPONSORED ADSsponsored ads | $553,000,000 | +23164.6% | 6,232 | -65.4% | 5.77% | +976.3% |
| QURE | Sell | UNIQURE N.V. COM EUR0.05 | $446,500,000 | +3682.9% | 8,318 | -94.7% | 4.66% | +75.0% |
| KALV | Sell | KALVISTA PHARMACEUTICALS | $383,233,000 | +3446.8% | 3,760 | -99.0% | 4.00% | +64.1% |
| TVTX | Sell | TRAVERE THERAPEUTICS INC | $380,000,000 | +24416.1% | 9,215 | -97.6% | 3.96% | +1032.6% |
| EXEL | New | EXELIXIS INC COM | $350,000,000 | – | 7,290 | +100.0% | 3.65% | – |
| KDNY | Sell | CHINOOK THERAPEUTICS INC | $340,389,000 | +7120.8% | 5,947 | -98.3% | 3.55% | +234.1% |
| SUPN | Sell | SUPERNUS PHARMACEUTICALS | $297,500,000 | +1602.1% | 8,604 | -97.1% | 3.10% | -21.3% |
| HZNP | Sell | HORIZON THERAPEUTICS PLC | $286,973,000 | +3751.5% | 22,915 | -87.5% | 2.99% | +78.2% |
| VERA | Sell | VERA THERAPEUTICScl a | $281,057,000 | +2320.2% | 3,825 | -98.0% | 2.93% | +12.0% |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS I | $273,000,000 | +9526.2% | 3,011 | -94.8% | 2.85% | +345.0% |
| New | CARIBOU BIOSCIENCES INC C | $254,692,000 | – | 1,378 | +100.0% | 2.66% | – | |
| INCY | Sell | INCYTE CORP INC COM | $238,000,000 | +9135.5% | 18,081 | -92.4% | 2.48% | +327.4% |
| NBIX | Sell | NEUROCRINE BIOSCIENCES IN | $236,000,000 | +7396.8% | 23,008 | -88.7% | 2.46% | +246.8% |
| HRMY | Sell | Harmony Biosciences Holdi | $221,500,000 | +978.8% | 10,794 | -94.7% | 2.31% | -50.1% |
| FULC | Sell | FULCRUM THERAPEUTICS INC | $193,741,000 | +23158.2% | 949 | -98.9% | 2.02% | +975.0% |
| RARE | Sell | ULTRAGENYX PHARMACEUTICAL | $161,100,000 | +7671.3% | 9,610 | -95.9% | 1.68% | +259.0% |
| FATE | Sell | FATE THERAPEUTICS INC COM | $158,000,000 | +2700.9% | 3,917 | -86.0% | 1.65% | +29.6% |
| GILD | Sell | GILEAD SCIENCES INC COMMO | $145,784,000 | +13398.5% | 9,012 | -89.8% | 1.52% | +523.4% |
| MRTX | Sell | MIRATI THERAPEUTICS INC C | $136,000,000 | +9805.3% | 9,131 | -95.2% | 1.42% | +357.7% |
| NVAX | Sell | NOVAVAX INC | $132,500,000 | +614.3% | 6,814 | -94.9% | 1.38% | -67.0% |
| GLPG | New | GALAPAGOSsponsored adr | $123,300,000 | – | 6,876 | +100.0% | 1.29% | – |
| CCXI | Sell | CHEMOCENTRYX INC COM STK | $121,100,000 | +9116.1% | 3,000 | -91.7% | 1.26% | +326.7% |
| IDYA | Sell | IDEAYA BIOSCIENCES INC CO | $109,000,000 | +6616.0% | 1,501 | -98.6% | 1.14% | +210.7% |
| GMDA | Sell | GAMIDA CELL | $107,000,000 | +971.6% | 187 | -99.8% | 1.12% | -50.4% |
| FOLD | Sell | AMICUS THERAPEUTICS INC C | $94,600,000 | +8547.2% | 1,017 | -98.9% | 0.99% | +299.6% |
| BMRN | Sell | BIOMARIN PHARMACEUTICAL I | $79,656,000 | +33796.2% | 6,601 | -91.7% | 0.83% | +1467.9% |
| ZLAB | Sell | ZAI LAB LTD ADRadr | $78,958,000 | +365.6% | 2,736 | -96.5% | 0.82% | -78.5% |
| GH | Sell | GUARDANT HEALTH INC COM | $74,500,000 | +27390.8% | 3,005 | -96.0% | 0.78% | +1173.8% |
| HCM | Sell | HUTCHMED CHINA LIMITED SPsponsored ads | $68,000,000 | +575.7% | 859 | -98.7% | 0.71% | -68.8% |
| SGEN | Sell | SEAGEN INC COM | $65,600,000 | +29055.6% | 11,607 | -84.8% | 0.68% | +1241.2% |
| ITCI | Sell | INTRA-CELLULAR THERAPIES | $63,156,000 | +201.7% | 3,603 | -92.9% | 0.66% | -86.0% |
| RCKT | Sell | ROCKET PHARMACEUTICALS IN | $63,000,000 | +252.3% | 868 | -98.6% | 0.66% | -83.7% |
| IRWD | New | IRONWOOD PHARMACEUTICALS | $60,000,000 | – | 692 | +100.0% | 0.63% | – |
| IMVT | Sell | IMMUNOVANT INC COM | $60,000,000 | +6950.5% | 233 | -99.6% | 0.63% | +226.0% |
| GMAB | New | GENMAB -SP ADRsponsored ads | $57,189,000 | – | 1,857 | +100.0% | 0.60% | – |
| BCRX | Sell | BIOCRYST PHARMACEUTICALS | $57,000,000 | +195.6% | 602 | -98.9% | 0.60% | -86.3% |
| BIIB | New | BIOGEN INC COMMON STOCK | $52,000,000 | – | 10,606 | +100.0% | 0.54% | – |
| ALKS | New | ALKERMES PLC SHS | $51,000,000 | – | 1,519 | +100.0% | 0.53% | – |
| ALLO | Sell | ALLOGENE THERAPEUTICS INC | $50,000,000 | +6593.4% | 570 | -98.9% | 0.52% | +210.7% |
| AVDL | Sell | AVADEL PHARMACEUTICALS PLsponsored adr | $50,000,000 | +553.9% | 122 | -99.8% | 0.52% | -69.7% |
| ILMN | Sell | ILLUMINA INC COM | $48,000,000 | +346.0% | 8,850 | -81.6% | 0.50% | -79.4% |
| IONS | Sell | IONIS PHARMACEUTICALS INC | $46,088,000 | +1297.0% | 1,703 | -98.9% | 0.48% | -35.3% |
| KRYS | Sell | KRYSTAL BIOTECH INC COM | $45,000,000 | +3968.7% | 2,955 | -93.4% | 0.47% | +88.4% |
| Sell | BLACK DIAMOND THERAPEUTIC | $44,000,000 | +2006.3% | 107 | -99.8% | 0.46% | -2.5% | |
| AMGN | Sell | AMGEN INC COM | $40,746,000 | +25.1% | 9,915 | -85.1% | 0.42% | -94.2% |
| INSM | Sell | INSMED INC COM PAR $.01 | $40,100,000 | +181.1% | 791 | -98.0% | 0.42% | -87.0% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS I | $38,000,000 | +75.1% | 5,542 | -85.4% | 0.40% | -91.9% |
| DNLI | Sell | DENALI THERAPEUTICS INC C | $38,000,000 | +363.9% | 1,118 | -97.1% | 0.40% | -78.6% |
| CRSP | New | CRISPR THERAPEUTICS AG COnamen akt | $34,200,000 | – | 2,078 | +100.0% | 0.36% | – |
| APLS | Sell | APELLIS PHARMACEUTICALS I | $32,500,000 | +2015.9% | 1,470 | -95.5% | 0.34% | -2.0% |
| NVCR | New | Novocure Ltd | $32,000,000 | – | 2,224 | +100.0% | 0.33% | – |
| ICPT | New | INTERCEPT PHARMACEUTICALS | $32,000,000 | – | 441 | +100.0% | 0.33% | – |
| SNY | Sell | SANOFIsponsored adr | $31,500,000 | +312.2% | 1,576 | -95.0% | 0.33% | -80.9% |
| ASND | Sell | ASCENDIS PHARMA A/S SPONSsponsored adr | $29,400,000 | +1406.9% | 2,733 | -90.7% | 0.31% | -30.2% |
| BNTX | New | BIONTECH SE ADSsponsored ads | $25,800,000 | – | 3,847 | +100.0% | 0.27% | – |
| XENE | Sell | XENON PHARMACEUTICALS INC | $25,500,000 | +697.4% | 774 | -97.0% | 0.27% | -63.1% |
| NTLA | Sell | INTELLIA THERAPEUTICS INC | $24,000,000 | +4596.7% | 1,242 | -94.8% | 0.25% | +117.4% |
| REGN | Buy | REGENERON PHARMACEUTICALS | $23,700,000 | +953.8% | 14,010 | +15.8% | 0.25% | -51.3% |
| BEAM | New | BEAM THERAPEUTICS INC COM | $23,500,000 | – | 910 | +100.0% | 0.24% | – |
| AGIO | Sell | AGIOS PHARMACEUTICALS INC | $21,500,000 | +2941.0% | 476 | -97.8% | 0.22% | +40.9% |
| PTCT | Sell | PTC THERAPEUTICS INC COM | $21,000,000 | +3303.6% | 842 | -99.8% | 0.22% | +57.6% |
| UTHR | Sell | UNITED THERAPEUTICS CORP | $20,000,000 | +579.1% | 4,713 | -76.4% | 0.21% | -68.5% |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $19,500,000 | +2113.4% | 985 | -94.9% | 0.20% | +2.0% |
| JAZZ | Sell | JAZZ PHARMACEUTICALS PLC | $17,200,000 | +190.3% | 2,683 | -84.4% | 0.18% | -86.6% |
| SWTX | Sell | SPRINGWORKS THERAPEUTICS | $16,300,000 | +1085.5% | 401 | -97.5% | 0.17% | -45.2% |
| PTGX | New | PROTAGONIST THERAPEUTICS | $16,185,000 | – | 128 | +100.0% | 0.17% | – |
| BGNE | Sell | BEIGENE LTD SPONSORED ADRsponsored adr | $15,700,000 | +37.7% | 2,542 | -83.8% | 0.16% | -93.6% |
| PRTA | Sell | PROTHENA CORP PLC USD0.01 | $15,000,000 | -37.1% | 407 | -97.3% | 0.16% | -97.1% |
| AXSM | Sell | AXSOME THERAPEUTICS INC. | $14,000,000 | +159.2% | 535 | -96.2% | 0.15% | -88.0% |
| KRTX | New | KARUNA THERAPEUTICS INC C | $12,400,000 | – | 1,567 | +100.0% | 0.13% | – |
| RLMD | Sell | RELMADA THERAPEUTICS INC | $10,000,000 | +1249.5% | 190 | -98.1% | 0.10% | -37.7% |
| ANAB | Sell | ANAPTYSBIO INC COM | $10,000,000 | +2773.6% | 203 | -98.0% | 0.10% | +33.3% |
| MDGL | Sell | MADRIGAL PHARMACEUTICALS | $5,350,000 | +5.6% | 383 | -92.8% | 0.06% | -95.1% |
| LEGN | Sell | Legend Biotech Corpsponsored ads | $4,500,000 | -20.1% | 248 | -94.5% | 0.05% | -96.3% |
| Sell | 2SEVENTY BIO INC COM | $3,666,000 | +3800.0% | 48 | -98.7% | 0.04% | +81.0% | |
| NKTX | Exit | NKARTA | $0 | – | -10,034 | -100.0% | -0.05% | – |
| ORIC | Exit | ORIC PHARMS. | $0 | – | -176,217 | -100.0% | -0.20% | – |
| GBT | Exit | GBL. BLOOD THERAPEUTICS | $0 | – | -151,800 | -100.0% | -0.37% | – |
| HARP | Exit | HARPOON THERAPEUTICS | $0 | – | -151,445 | -100.0% | -0.62% | – |
| VRTX | Exit | VERTEX PHARMS. | $0 | – | -25,122 | -100.0% | -0.73% | – |
| TPTX | Exit | TURNING POINT THERAPEUTIC | $0 | – | -14,093 | -100.0% | -1.96% | – |
| BHVN | Exit | BIOHAVEN PHARM. HLDG. | $0 | – | -130,900 | -100.0% | -2.10% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-08-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| GILEAD SCIENCES INC COMMO | 28 | Q3 2023 | 9.3% |
| INCYTE CORP INC COM | 28 | Q3 2023 | 7.9% |
| BIOMARIN PHARMACEUTICALS INC | 28 | Q3 2023 | 7.5% |
| REGENERON PHARMS. | 27 | Q3 2023 | 9.0% |
| BIOGEN INC COMMON STOCK | 26 | Q3 2023 | 8.7% |
| VERTEX PHARMS. | 25 | Q3 2023 | 8.4% |
| AMGEN INC COM | 25 | Q3 2023 | 7.9% |
| NEUROCRINE BIOSCIENCES INC | 25 | Q3 2023 | 6.9% |
| ALYNYLAM PHARMACEUTICALS INC | 25 | Q3 2023 | 6.7% |
| IONIS PHARMS. | 25 | Q3 2023 | 4.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Altus Pharmaceuticals Inc. | February 12, 2009 | ? | ? |
| MICROMET, INC. | February 14, 2008 | 1,907,390 | 4.7% |
| EPIMMUNE INC | February 15, 2005 | 1,279,659 | 8.0% |
| ESSENTIAL THERAPEUTICS INC | April 29, 2003 | 2,500,000 | 11.7% |
| TARGETED GENETICS CORP /WA/ | April 18, 2003 | ? | ? |
| ESSENTIAL THERAPEUTICS INC | November 05, 2001 | 11 | 13.0% |
| ONYX PHARMACEUTICALS INC | October 15, 2001 | 11 | 13.0% |
| CORVAS INTERNATIONAL INC | October 12, 2001 | 11 | 13.0% |
| RIBOZYME PHARMACEUTICALS INC | October 05, 2001 | 11 | 13.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-08 |
| 13F-HR | 2023-05-18 |
| 13F-HR | 2023-02-01 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-16 |
| 13F-HR | 2022-05-20 |
| 13F-HR | 2022-02-15 |
| 13F-HR | 2021-11-12 |
| 13F-HR | 2021-08-11 |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.