$330 Million is the total value of INTERNATIONAL BIOTECHNOLOGY TRUST PLC's 70 reported holdings in Q1 2022. The portfolio turnover from Q4 2021 to Q1 2022 was 26.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| AMGN | Sell | AMGEN INC COM | $32,565,000 | 0.0% | 66,746 | -53.9% | 7.34% | +1.2% |
| PRTA | Prothena Corp PLC USD0.01 | $23,848,000 | +3118.4% | 15,000 | 0.0% | 5.38% | +3159.4% | |
| ALNY | Sell | ALNYLAM PHARMS. | $21,706,000 | 0.0% | 38,000 | -70.3% | 4.90% | +1.2% |
| ITCI | Sell | INTRA-CELLULAR THERAPIES | $20,930,000 | +253.3% | 50,956 | -55.1% | 4.72% | +257.6% |
| HRMY | Sell | HARMONY BIOSCIENCES HLDGS | $20,533,000 | +104.0% | 205,474 | -12.9% | 4.63% | +106.6% |
| BCRX | New | BIOCRYST PHARMS. | $19,282,000 | – | 57,000 | +100.0% | 4.35% | – |
| NVAX | New | NOVAVAX | $18,549,000 | – | 132,500 | +100.0% | 4.18% | – |
| RCKT | ROCKET PHARMS. | $17,884,000 | +1200.7% | 63,000 | 0.0% | 4.03% | +1218.0% | |
| SUPN | SUPERNUS PHARMS. | $17,478,000 | +101.5% | 297,500 | 0.0% | 3.94% | +103.9% | |
| ZLAB | Buy | Zai Lab Ltd ADR (V1 Ord)adr | $16,958,000 | +593.0% | 78,958 | +102.7% | 3.82% | +601.7% |
| INSM | Sell | INSMED | $14,266,000 | +332.4% | 40,100 | -66.9% | 3.22% | +337.7% |
| QURE | Uniqure B V EUR0.05 | $11,803,000 | +266.0% | 155,500 | 0.0% | 2.66% | +270.8% | |
| VERA | Buy | VERA THERAPEUTICScl a | $11,613,000 | +263.1% | 190,749 | +58.3% | 2.62% | +267.8% |
| BGNE | Sell | BEIGENE ADRsponsored adr | $11,398,000 | +111.0% | 15,700 | -21.5% | 2.57% | +113.5% |
| KALV | KALVISTA PHARMS. | $10,805,000 | +113.3% | 383,233 | 0.0% | 2.44% | +115.9% | |
| ILMN | Buy | ILLUMINA | $10,762,000 | -24.6% | 48,000 | +28.0% | 2.43% | -23.6% |
| HCM | Hutchmed China Ltd ADR(V0.5 Ord)sponsored ads | $10,063,000 | +323.3% | 68,000 | 0.0% | 2.27% | +328.1% | |
| GMDA | Gamida Cell Ltd COM USD0.01 | $9,985,000 | +3584.5% | 107,000 | 0.0% | 2.25% | +3653.3% | |
| BHVN | Sell | BIOHAVEN PHARM. HLDG. | $9,291,000 | -51.8% | 130,900 | -6.4% | 2.10% | -51.2% |
| TPTX | Sell | TURNING POINT THERAPEUTIC | $8,675,000 | +194.6% | 14,093 | -77.2% | 1.96% | +198.2% |
| DNLI | Buy | DENALI THERAPEUTICS | $8,192,000 | +607.4% | 38,000 | +46.2% | 1.85% | +615.9% |
| AVDL | New | AVADEL PHARMS.sponsored adr | $7,647,000 | – | 50,000 | +100.0% | 1.72% | – |
| SNY | New | SANOFIsponsored adr | $7,641,000 | – | 31,500 | +100.0% | 1.72% | – |
| HZNP | Buy | HORIZON THERAPEUTICS | $7,451,000 | -30.8% | 183,473 | +83.7% | 1.68% | -29.9% |
| JAZZ | Sell | JAZZ PHARMS. | $5,924,000 | +5.2% | 17,200 | -61.1% | 1.34% | +6.5% |
| FATE | FATE THERAPEUTICS | $5,641,000 | +244.4% | 28,000 | 0.0% | 1.27% | +248.5% | |
| LEGN | LEGEND BIOTECHsponsored ads | $5,632,000 | +2594.7% | 4,500 | 0.0% | 1.27% | +2602.1% | |
| AXSM | New | AXSOME THERAPEUTICS | $5,402,000 | – | 14,000 | +100.0% | 1.22% | – |
| MDGL | New | MADRIGAL PHARMS. | $5,066,000 | – | 5,350 | +100.0% | 1.14% | – |
| KDNY | Buy | CHINOOK THERAPEUTICS | $4,714,000 | 0.0% | 340,389 | +17.6% | 1.06% | +1.2% |
| AUPH | Buy | Aurinia Pharmaceuticals Inc Com NPV | $3,955,000 | -48.3% | 435,000 | +30.0% | 0.89% | -47.7% |
| IONS | Sell | IONIS PHARMS. | $3,299,000 | -69.5% | 154,088 | -56.6% | 0.74% | -69.1% |
| VRTX | Sell | VERTEX PHARMS. | $3,225,000 | -81.0% | 25,122 | -67.5% | 0.73% | -80.8% |
| XENE | Xenon Pharmaceuticals Inc NPV | $3,198,000 | +301.3% | 25,500 | 0.0% | 0.72% | +305.1% | |
| NBIX | Sell | NEUROCRINE BIOSCIENCES | $3,148,000 | -86.8% | 203,000 | -27.5% | 0.71% | -86.6% |
| UTHR | New | UTD. THERAPEUTICS | $2,945,000 | – | 20,000 | +100.0% | 0.66% | – |
| IOVA | IOVANCE BIOTHERAPEUTICS | $2,836,000 | +156.4% | 58,000 | 0.0% | 0.64% | +160.2% | |
| HARP | Sell | HARPOON THERAPEUTICS | $2,771,000 | +70.7% | 151,445 | -29.6% | 0.62% | +72.7% |
| INCY | Sell | INCYTE | $2,577,000 | -87.7% | 238,000 | -16.5% | 0.58% | -87.5% |
| IMAB | I-MAB-SPONSORED ADRsponsored ads | $2,377,000 | +179.3% | 18,000 | 0.0% | 0.54% | +182.1% | |
| REGN | REGENERON PHARMS. | $2,249,000 | -70.6% | 12,100 | 0.0% | 0.51% | -70.2% | |
| New | BLACK DIAMOND THERAPEUTIC | $2,089,000 | – | 44,000 | +100.0% | 0.47% | – | |
| RARE | Buy | ULTRAGENYX PHARM. | $2,073,000 | -82.1% | 233,100 | +68.8% | 0.47% | -81.9% |
| ASND | ASCENDIS PHARMA ADRsponsored adr | $1,951,000 | -50.7% | 29,400 | 0.0% | 0.44% | -50.1% | |
| GBT | Buy | GBL. BLOOD THERAPEUTICS | $1,638,000 | -40.9% | 151,800 | +60.1% | 0.37% | -40.2% |
| IDYA | IDEAYA BIOSCIENCES | $1,623,000 | -37.0% | 109,000 | 0.0% | 0.37% | -36.2% | |
| TVTX | TRAVERE THERAPEUTICS INC | $1,550,000 | -86.9% | 380,000 | 0.0% | 0.35% | -86.7% | |
| APLS | APELLIS PHARMS. | $1,536,000 | 0.0% | 32,500 | 0.0% | 0.35% | +1.2% | |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $1,373,000 | -92.6% | 188,500 | +49.0% | 0.31% | -92.5% |
| SWTX | Sell | SPRINGWORKS THERAPEUTICS | $1,375,000 | -11.3% | 16,300 | -34.8% | 0.31% | -10.1% |
| CCXI | CHEMOCENTRYX | $1,314,000 | 0.0% | 36,100 | 0.0% | 0.30% | +1.0% | |
| DYN | DYNE THERAPEUTICS | $1,158,000 | -79.5% | 476,000 | 0.0% | 0.26% | -79.2% | |
| KRYS | KRYSTAL BIOTECH | $1,106,000 | -64.9% | 45,000 | 0.0% | 0.25% | -64.5% | |
| FOLD | AMICUS THERAPEUTICS | $1,094,000 | 0.0% | 94,600 | 0.0% | 0.25% | +1.2% | |
| GILD | Sell | GILEAD SCIENCES | $1,080,000 | -94.7% | 88,784 | -68.6% | 0.24% | -94.7% |
| ORIC | Buy | ORIC PHARMS. | $905,000 | -59.8% | 176,217 | +15.2% | 0.20% | -59.3% |
| BPMC | BLUEPRINT MEDICINES | $881,000 | -57.8% | 19,500 | 0.0% | 0.20% | -57.2% | |
| IMVT | IMMUNOVANT | $851,000 | +66.5% | 60,000 | 0.0% | 0.19% | +68.4% | |
| FULC | Buy | FULCRUM THERAPEUTICS INC | $833,000 | -22.9% | 82,741 | +35.6% | 0.19% | -22.0% |
| ALLO | ALLOGENE THERAPEUTICS | $747,000 | 0.0% | 50,000 | 0.0% | 0.17% | +1.2% | |
| RLMD | RELMADA THERAPEUTICS | $741,000 | +229.3% | 10,000 | 0.0% | 0.17% | +234.0% | |
| AGIO | AGIOS PHARMS. | $707,000 | 0.0% | 21,500 | 0.0% | 0.16% | +0.6% | |
| PTCT | Sell | PTC THERAPEUTICS | $617,000 | -96.5% | 411,000 | -8.5% | 0.14% | -96.5% |
| NTLA | INTELLIA THERAPEUTICS | $511,000 | -82.0% | 24,000 | 0.0% | 0.12% | -81.8% | |
| ANAB | ANAPTYSBIO | $348,000 | 0.0% | 10,000 | 0.0% | 0.08% | 0.0% | |
| GH | GUARDANT HEALTH | $271,000 | -96.4% | 74,500 | 0.0% | 0.06% | -96.3% | |
| BMRN | Sell | BIOMARIN PHARM. | $235,000 | -97.5% | 79,656 | -24.2% | 0.05% | -97.4% |
| SGEN | Sell | SEAGEN | $225,000 | -98.7% | 76,200 | -32.7% | 0.05% | -98.7% |
| NKTX | Sell | NKARTA | $209,000 | -66.1% | 10,034 | -75.0% | 0.05% | -65.7% |
| 2SEVENTY BIO INC-W/I | $94,000 | 0.0% | 3,666 | 0.0% | 0.02% | 0.0% | ||
| BDTX | Exit | BLACK DIAMOND THERAPEUTICS I | $0 | – | -44,000 | -100.0% | -0.05% | – |
| EXAS | Exit | Exact Sciences Corp | $0 | – | -10,700 | -100.0% | -0.19% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INC | $0 | – | -52,800 | -100.0% | -0.20% | – |
| NKTR | Exit | NEKTAR THERAPEUTICS | $0 | – | -67,000 | -100.0% | -0.20% | – |
| KOD | Exit | KODIAK SCIENCES INC | $0 | – | -16,200 | -100.0% | -0.31% | – |
| ARNA | Exit | Arena Pharmaceuticals Inc | $0 | – | -21,000 | -100.0% | -0.44% | – |
| STRO | Exit | SUTRO BIOPHARMA INC | $0 | – | -139,331 | -100.0% | -0.46% | – |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -135,000 | -100.0% | -0.49% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -108,200 | -100.0% | -1.82% | – |
| EXC | Exit | Exelixis Inc | $0 | – | -546,534 | -100.0% | -2.22% | – |
| BIIB | Exit | Biogen Inc | $0 | – | -47,500 | -100.0% | -2.54% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-05-20
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| GILEAD SCIENCES INC COMMO | 28 | Q3 2023 | 9.3% |
| INCYTE CORP INC COM | 28 | Q3 2023 | 7.9% |
| BIOMARIN PHARMACEUTICALS INC | 28 | Q3 2023 | 7.5% |
| REGENERON PHARMS. | 27 | Q3 2023 | 9.0% |
| BIOGEN INC COMMON STOCK | 26 | Q3 2023 | 8.7% |
| VERTEX PHARMS. | 25 | Q3 2023 | 8.4% |
| AMGEN INC COM | 25 | Q3 2023 | 7.9% |
| NEUROCRINE BIOSCIENCES INC | 25 | Q3 2023 | 6.9% |
| ALYNYLAM PHARMACEUTICALS INC | 25 | Q3 2023 | 6.7% |
| IONIS PHARMS. | 25 | Q3 2023 | 4.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Altus Pharmaceuticals Inc. | February 12, 2009 | ? | ? |
| MICROMET, INC. | February 14, 2008 | 1,907,390 | 4.7% |
| EPIMMUNE INC | February 15, 2005 | 1,279,659 | 8.0% |
| ESSENTIAL THERAPEUTICS INC | April 29, 2003 | 2,500,000 | 11.7% |
| TARGETED GENETICS CORP /WA/ | April 18, 2003 | ? | ? |
| ESSENTIAL THERAPEUTICS INC | November 05, 2001 | 11 | 13.0% |
| ONYX PHARMACEUTICALS INC | October 15, 2001 | 11 | 13.0% |
| CORVAS INTERNATIONAL INC | October 12, 2001 | 11 | 13.0% |
| RIBOZYME PHARMACEUTICALS INC | October 05, 2001 | 11 | 13.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-08 |
| 13F-HR | 2023-05-18 |
| 13F-HR | 2023-02-01 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-16 |
| 13F-HR | 2022-05-20 |
| 13F-HR | 2022-02-15 |
| 13F-HR | 2021-11-12 |
| 13F-HR | 2021-08-11 |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.