$3.14 Billion is the total value of EcoR1 Capital, LLC's 76 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 52.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | $557,443,000 | -30.6% | 11,284,280 | 0.0% | 17.76% | -36.5% | |
| ANAB | ANAPTYSBIO INC | $261,356,000 | +28.1% | 7,521,024 | 0.0% | 8.33% | +17.4% | |
| RCUS | Buy | ARCUS BIOSCIENCES INC | $223,530,000 | +25.1% | 5,523,358 | +7.8% | 7.12% | +14.6% |
| XNCR | XENCOR INC | $196,833,000 | +22.8% | 4,906,106 | 0.0% | 6.27% | +12.5% | |
| APLS | New | APELLIS PHARMACEUTICALS INC | $190,722,000 | – | 4,033,882 | +100.0% | 6.08% | – |
| MORF | MORPHIC HLDG INC | $187,225,000 | -16.3% | 3,951,566 | 0.0% | 5.97% | -23.4% | |
| GLPG | Buy | GALAPAGOS NVspon adr | $122,631,000 | +49.5% | 2,224,403 | +42.7% | 3.91% | +37.0% |
| NUVB | Buy | NUVATION BIO INC | $118,121,000 | -13.3% | 13,896,543 | +1.3% | 3.76% | -20.6% |
| ALEC | ALECTOR INC | $103,146,000 | -9.5% | 4,994,970 | 0.0% | 3.29% | -17.1% | |
| PTGX | Buy | PROTAGONIST THERAPEUTICS INC | $90,278,000 | +252.9% | 2,639,706 | +82.8% | 2.88% | +223.3% |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $81,652,000 | – | 1,077,483 | +100.0% | 2.60% | – |
| GRTS | Buy | GRITSTONE BIO INC | $77,317,000 | +28.7% | 6,012,232 | +8.1% | 2.46% | +18.0% |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $71,434,000 | – | 3,060,593 | +100.0% | 2.28% | – |
| RNA | AVIDITY BIOSCIENCES INC | $65,593,000 | -3.5% | 2,759,505 | 0.0% | 2.09% | -11.6% | |
| ITOS | ITEOS THERAPEUTICS INC | $60,675,000 | +72.4% | 1,303,157 | 0.0% | 1.93% | +58.0% | |
| RLAY | Buy | RELAY THERAPEUTICS INC | $54,636,000 | +25.1% | 1,779,084 | +28.4% | 1.74% | +14.5% |
| KURA | KURA ONCOLOGY INC | $52,142,000 | -25.3% | 3,724,437 | 0.0% | 1.66% | -31.5% | |
| ORIC | ORIC PHARMACEUTICALS INC | $50,993,000 | -29.7% | 3,468,944 | 0.0% | 1.62% | -35.6% | |
| New | 2SEVENTY BIO ORD | $49,134,000 | – | 1,917,063 | +100.0% | 1.57% | – | |
| AVIR | New | ATEA PHARMACEUTICALS INC | $48,063,000 | – | 5,376,134 | +100.0% | 1.53% | – |
| DSGN | Buy | DESIGN THERAPEUTICS INC | $46,096,000 | +68.4% | 2,152,997 | +15.6% | 1.47% | +54.3% |
| SAGE | New | SAGE THERAPEUTICS INC | $40,015,000 | – | 940,636 | +100.0% | 1.28% | – |
| JANX | JANUX THERAPEUTICS INC | $27,858,000 | -8.8% | 1,411,975 | 0.0% | 0.89% | -16.4% | |
| New | PARDES BIOSCIENCES ORD | $26,145,000 | – | 1,597,139 | +100.0% | 0.83% | – | |
| New | VENTYX BIOSCIENCES ORD | $25,818,000 | – | 1,300,000 | +100.0% | 0.82% | – | |
| EWTX | EDGEWISE THERAPEUTICS INC | $19,546,000 | -7.9% | 1,279,175 | 0.0% | 0.62% | -15.7% | |
| OVID | OVID THERAPEUTICS INC | $19,524,000 | -4.5% | 6,082,200 | 0.0% | 0.62% | -12.5% | |
| AKUS | AKOUOS INC | $16,796,000 | -26.8% | 1,975,984 | 0.0% | 0.54% | -33.0% | |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $16,767,000 | – | 590,169 | +100.0% | 0.53% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $16,644,000 | – | 98,146 | +100.0% | 0.53% | – |
| SLDB | SOLID BIOSCIENCES INC | $16,105,000 | -26.8% | 9,202,702 | 0.0% | 0.51% | -32.9% | |
| HALO | New | HALOZYME THERAPEUTICS INC | $15,762,000 | – | 392,000 | +100.0% | 0.50% | – |
| LEGN | New | LEGEND BIOTECH CORPsponsored ads | $14,337,000 | – | 307,594 | +100.0% | 0.46% | – |
| TANGO THERAPEUTICS INC | $14,222,000 | -15.4% | 1,300,000 | 0.0% | 0.45% | -22.6% | ||
| ERASCA INC | $10,906,000 | -26.6% | 700,000 | 0.0% | 0.35% | -32.7% | ||
| ARVN | New | ARVINAS INC | $10,703,000 | – | 130,300 | +100.0% | 0.34% | – |
| CNTA | Buy | CENTESSA PHARMACEUTICALS PLCsponsored ads | $9,933,000 | -21.2% | 882,176 | +16.9% | 0.32% | -27.6% |
| IMVT | IMMUNOVANT INC | $9,720,000 | -2.0% | 1,140,819 | 0.0% | 0.31% | -10.1% | |
| VYGR | Buy | VOYAGER THERAPEUTICS INC | $9,641,000 | +721.9% | 3,557,507 | +697.7% | 0.31% | +648.8% |
| NRIX | Sell | NURIX THERAPEUTICS INC | $8,961,000 | -73.5% | 309,540 | -72.5% | 0.29% | -75.6% |
| GRPH | New | GRAPHITE BIO INC | $8,563,000 | – | 688,900 | +100.0% | 0.27% | – |
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $8,188,000 | -14.5% | 963,333 | 0.0% | 0.26% | -21.6% | |
| SBTX | Sell | SILVERBACK THERAPEUTICS INC | $7,060,000 | -40.3% | 1,060,010 | -10.5% | 0.22% | -45.3% |
| CCCC | C4 THERAPEUTICS INC | $6,440,000 | -27.9% | 200,000 | 0.0% | 0.20% | -34.1% | |
| FLAC | FRAZIER LIFESCIENCES ACQU CO | $5,729,000 | -0.7% | 587,615 | 0.0% | 0.18% | -9.0% | |
| AMTI | New | APPLIED MOLECULAR TRANS INC | $5,592,000 | – | 400,000 | +100.0% | 0.18% | – |
| KRON | KRONOS BIO INC | $5,264,000 | -35.2% | 387,357 | 0.0% | 0.17% | -40.4% | |
| JYAC | JIYA ACQUISITION CORP | $4,885,000 | +0.2% | 500,000 | 0.0% | 0.16% | -8.2% | |
| NLTX | NEOLEUKIN THERAPEUTICS INC | $4,148,000 | -33.3% | 860,619 | 0.0% | 0.13% | -38.9% | |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 ORD | $4,032,000 | +1.9% | 400,000 | 0.0% | 0.13% | -7.2% | |
| GRTS | New | GRITSTONE BIO INCcall | $3,948,000 | – | 307,000 | +100.0% | 0.13% | – |
| ACIU | Sell | AC IMMUNE SA | $3,710,000 | -26.4% | 749,585 | -0.2% | 0.12% | -32.6% |
| VERV | VERVE THERAPEUTICS INC | $3,687,000 | -21.6% | 100,000 | 0.0% | 0.12% | -28.7% | |
| KNTE | KINNATE BIOPHARMA INC | $3,101,000 | -23.0% | 175,000 | 0.0% | 0.10% | -29.3% | |
| DYN | DYNE THERAPEUTICS INC | $2,556,000 | -28.4% | 215,000 | 0.0% | 0.08% | -34.7% | |
| HLXA | HELIX ACQUISITION CORP | $1,978,000 | -0.6% | 200,000 | 0.0% | 0.06% | -8.7% | |
| FVAM | 5 01 ACQUISITION CORP | $1,970,000 | +0.3% | 200,000 | 0.0% | 0.06% | -7.4% | |
| BLSA | BCLS ACQUISITION CORP | $1,960,000 | -1.6% | 200,000 | 0.0% | 0.06% | -10.1% | |
| EUCR | EUCRATES BIOMEDICAL ACQU COR | $1,952,000 | -0.2% | 200,000 | 0.0% | 0.06% | -8.8% | |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $1,842,000 | – | 1,046,700 | +100.0% | 0.06% | – |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $1,487,000 | -1.4% | 150,000 | 0.0% | 0.05% | -9.6% | |
| PMVP | PMV PHARMACEUTICALS INC | $1,155,000 | -22.5% | 50,000 | 0.0% | 0.04% | -28.8% | |
| CARIBOU BIOSCIENCES INC | $1,132,000 | -36.8% | 75,000 | 0.0% | 0.04% | -41.9% | ||
| RPTX | REPARE THERAPEUTICS INC | $1,055,000 | -18.0% | 50,000 | 0.0% | 0.03% | -24.4% | |
| ALGS | New | ALIGOS THERAPEUTICS INC | $1,081,000 | – | 91,044 | +100.0% | 0.03% | – |
| TMPM | TURMERIC ACQUISITION CORPcl a | $982,000 | +0.3% | 100,000 | 0.0% | 0.03% | -8.8% | |
| VTVT | New | VTV THERAPEUTICS INCcl a | $830,000 | – | 834,333 | +100.0% | 0.03% | – |
| CMAXW | CAREMAX INC*w exp 06/08/202 | $768,000 | -22.1% | 100,000 | 0.0% | 0.02% | -29.4% | |
| GLUE | New | MONTE ROSA THERAPEUTICS INC | $768,000 | – | 37,593 | +100.0% | 0.02% | – |
| BOLT | BOLT BIOTHERAPEUTICS INC | $735,000 | -60.2% | 150,000 | 0.0% | 0.02% | -64.1% | |
| FLACW | FRAZIER LIFESCIENCES ACQU CO*w exp 11/30/202 | $650,000 | -0.8% | 66,665 | 0.0% | 0.02% | -8.7% | |
| EUCRW | EUCRATES BIOMEDICAL ACQU COR*w exp 10/23/202 | $651,000 | -0.2% | 66,666 | 0.0% | 0.02% | -8.7% | |
| PCVX | New | VAXCYTE INC | $495,000 | – | 20,800 | +100.0% | 0.02% | – |
| OMEG | OMEGA ALPHA SPACcl a | $489,000 | +0.4% | 50,000 | 0.0% | 0.02% | -5.9% | |
| SURROZEN INC | $429,000 | -8.9% | 66,665 | 0.0% | 0.01% | -12.5% | ||
| TMPMW | TURMERIC ACQUISITION CORP*w exp 10/08/202 | $327,000 | +0.3% | 33,333 | 0.0% | 0.01% | -9.1% | |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -7,001 | -100.0% | -0.00% | – |
| SRRK | Exit | SCHOLAR ROCK HLDG CORP | $0 | – | -8,208 | -100.0% | -0.01% | – |
| MGTX | Exit | MEIRAGTX HLDGS PLC | $0 | – | -94,819 | -100.0% | -0.04% | – |
| BCAB | Exit | BIOATLA INC | $0 | – | -50,000 | -100.0% | -0.05% | – |
| FMTX | Exit | FORMA THERAPEUTICS HLDGS INC | $0 | – | -90,141 | -100.0% | -0.07% | – |
| IGMS | Exit | IGM BIOSCIENCES INC | $0 | – | -38,030 | -100.0% | -0.09% | – |
| FSII | Exit | FS DEVELOPMENT CORP II | $0 | – | -371,014 | -100.0% | -0.13% | – |
| CYCN | Exit | CYCLERION THERAPEUTICS INC | $0 | – | -1,606,276 | -100.0% | -0.17% | – |
| NGM | Exit | NGM BIOPHARMACEUTICALS INCcall | $0 | – | -245,000 | -100.0% | -0.17% | – |
| CRVS | Exit | CORVUS PHARMACEUTICALS INC | $0 | – | -2,081,077 | -100.0% | -0.35% | – |
| ODT | Exit | ODONATE THERAPEUTICS INC | $0 | – | -3,727,261 | -100.0% | -0.38% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -802,507 | -100.0% | -0.53% | – |
| DRNA | Exit | DICERNA PHARMACEUTICALS INC | $0 | – | -1,249,812 | -100.0% | -0.88% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORPcall | $0 | – | -250,000 | -100.0% | -0.90% | – |
| STTK | Exit | SHATTUCK LABS INC | $0 | – | -3,709,072 | -100.0% | -2.63% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -464,298 | -100.0% | -2.86% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.