$2.25 Billion is the total value of EcoR1 Capital, LLC's 71 reported holdings in Q1 2021. The portfolio turnover from Q4 2020 to Q1 2021 was 56.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PRTA | Buy | PROTHENA CORP PLC | $277,181,000 | +144.8% | 11,034,280 | +17.1% | 12.29% | +102.0% |
| XNCR | Buy | XENCOR INC | $211,007,000 | +6.4% | 4,900,306 | +7.8% | 9.36% | -12.2% |
| MORF | Buy | MORPHIC HLDG INC | $189,797,000 | +99.2% | 2,999,315 | +5.6% | 8.42% | +64.3% |
| ANAB | Buy | ANAPTYSBIO INC | $154,117,000 | +122.4% | 7,151,624 | +121.9% | 6.84% | +83.5% |
| NUVB | New | NUVATION BIO INC | $138,431,000 | – | 13,247,017 | +100.0% | 6.14% | – |
| RLAY | Buy | RELAY THERAPEUTICS INC | $118,553,000 | -10.9% | 3,429,363 | +7.1% | 5.26% | -26.5% |
| SBTX | SILVERBACK THERAPEUTICS INC | $110,542,000 | -5.8% | 2,533,635 | 0.0% | 4.90% | -22.3% | |
| KURA | Buy | KURA ONCOLOGY INC | $104,391,000 | +80.3% | 3,692,637 | +108.3% | 4.63% | +48.7% |
| MRTX | MIRATI THERAPEUTICS INC | $79,534,000 | -22.0% | 464,298 | 0.0% | 3.53% | -35.6% | |
| ORIC | ORIC PHARMACEUTICALS INC | $75,759,000 | -27.6% | 3,092,218 | 0.0% | 3.36% | -40.3% | |
| STTK | Buy | SHATTUCK LABS INC | $71,879,000 | -44.2% | 2,458,259 | +0.1% | 3.19% | -53.9% |
| NRIX | Buy | NURIX THERAPEUTICS INC | $62,771,000 | +23.6% | 2,019,019 | +30.8% | 2.78% | +2.0% |
| RCUS | ARCUS BIOSCIENCES INC | $61,661,000 | +8.2% | 2,195,892 | 0.0% | 2.74% | -10.7% | |
| SLDB | Buy | SOLID BIOSCIENCES INC | $50,891,000 | -15.8% | 9,202,702 | +15.4% | 2.26% | -30.6% |
| RNA | AVIDITY BIOSCIENCES INC | $45,887,000 | -14.5% | 2,103,950 | 0.0% | 2.04% | -29.5% | |
| EWTX | New | EDGEWISE THERAPEUTICS INC | $39,786,000 | – | 1,224,175 | +100.0% | 1.76% | – |
| NLTX | NEOLEUKIN THERAPEUTICS INC | $38,440,000 | -12.7% | 3,122,704 | 0.0% | 1.70% | -28.0% | |
| BCEL | ATRECA INC | $37,201,000 | -5.1% | 2,426,685 | 0.0% | 1.65% | -21.7% | |
| DSGN | New | DESIGN THERAPEUTICS INC | $34,024,000 | – | 1,137,940 | +100.0% | 1.51% | – |
| GRTS | GRITSTONE ONCOLOGY INC | $32,263,000 | +139.3% | 3,421,287 | 0.0% | 1.43% | +97.4% | |
| ACIU | Buy | AC IMMUNE SA | $27,763,000 | +122.8% | 3,648,163 | +51.4% | 1.23% | +83.7% |
| AKUS | AKOUOS INC | $27,407,000 | -30.1% | 1,975,984 | 0.0% | 1.22% | -42.3% | |
| OVID | New | OVID THERAPEUTICS INC | $24,450,000 | – | 6,082,200 | +100.0% | 1.08% | – |
| ARVN | New | ARVINAS INC | $21,066,000 | – | 318,704 | +100.0% | 0.93% | – |
| KDNY | CHINOOK THERAPEUTICS INC | $19,425,000 | -2.0% | 1,250,001 | 0.0% | 0.86% | -19.1% | |
| ALEC | New | ALECTOR INC | $12,136,000 | – | 602,600 | +100.0% | 0.54% | – |
| ELDN | New | ELEDON PHARMACEUTICALS INC | $11,938,000 | – | 1,115,721 | +100.0% | 0.53% | – |
| KRON | KRONOS BIO INC | $11,338,000 | -2.0% | 387,357 | 0.0% | 0.50% | -19.1% | |
| AMTI | Sell | APPLIED MOLECULAR TRANS INC | $10,538,000 | -70.2% | 239,443 | -79.2% | 0.47% | -75.4% |
| ALVR | ALLOVIR INC | $10,460,000 | -39.1% | 447,012 | 0.0% | 0.46% | -49.8% | |
| NUVBWS | New | NUVATION BIO INC*w exp 07/07/202 | $10,067,000 | – | 963,333 | +100.0% | 0.45% | – |
| TBIO | New | TRANSLATE BIO INC | $9,843,000 | – | 596,900 | +100.0% | 0.44% | – |
| BCTG | BCTG ACQUISITION CORP | $8,896,000 | -2.8% | 800,000 | 0.0% | 0.40% | -19.7% | |
| ITOS | ITEOS THERAPEUTICS INC | $8,887,000 | +1.1% | 260,000 | 0.0% | 0.39% | -16.7% | |
| ALPN | ALPINE IMMUNE SCIENCES INC | $7,858,000 | -15.9% | 741,290 | 0.0% | 0.35% | -30.5% | |
| SYRS | SYROS PHARMACEUTICALS INC | $7,480,000 | -31.1% | 1,000,000 | 0.0% | 0.33% | -43.1% | |
| CCCC | C4 THERAPEUTICS INC | $7,398,000 | +11.7% | 200,000 | 0.0% | 0.33% | -7.9% | |
| MGTA | New | MAGENTA THERAPEUTICS INC | $6,587,000 | – | 556,354 | +100.0% | 0.29% | – |
| PRTA | New | PROTHENA CORP PLCcall | $6,280,000 | – | 250,000 | +100.0% | 0.28% | – |
| LOGC | Sell | LOGICBIO THERAPEUTICS INC | $5,014,000 | -15.2% | 688,700 | -11.1% | 0.22% | -30.2% |
| BOLT | New | BOLT BIOTHERAPEUTICS INC | $4,937,000 | – | 150,000 | +100.0% | 0.22% | – |
| JYAC | JIYA ACQUISITION CORP | $4,920,000 | -4.5% | 500,000 | 0.0% | 0.22% | -21.3% | |
| CYCN | CYCLERION THERAPEUTICS INC | $4,482,000 | -8.8% | 1,606,276 | 0.0% | 0.20% | -24.6% | |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $4,476,000 | -12.6% | 400,000 | 0.0% | 0.20% | -27.6% | |
| NGM | NGM BIOPHARMACEUTICALS INC | $4,173,000 | -4.0% | 143,567 | 0.0% | 0.18% | -20.9% | |
| KYMR | KYMERA THERAPEUTICS INC | $3,886,000 | -37.3% | 100,000 | 0.0% | 0.17% | -48.3% | |
| DYN | DYNE THERAPEUTICS INC | $3,339,000 | -26.0% | 215,000 | 0.0% | 0.15% | -39.1% | |
| VINCW | VINCERX PHARMA INC*w exp 12/24/202 | $2,895,000 | -7.7% | 150,000 | 0.0% | 0.13% | -24.3% | |
| ARPO | New | AERPIO PHARMACEUTICALS INC | $2,674,000 | – | 2,072,782 | +100.0% | 0.12% | – |
| BCAB | BIOATLA INC | $2,542,000 | +49.4% | 50,000 | 0.0% | 0.11% | +24.2% | |
| BLSA | BCLS ACQUISITION CORP | $2,114,000 | -5.1% | 200,000 | 0.0% | 0.09% | -21.7% | |
| FLACU | FRAZIER LIFESCIENCES ACQU COunit 12/09/2025 | $2,032,000 | -2.1% | 200,000 | 0.0% | 0.09% | -19.6% | |
| HLXA | HELIX ACQUISITION CORP | $2,040,000 | -10.3% | 200,000 | 0.0% | 0.09% | -26.2% | |
| FVAM | 5 01 ACQUISITION CORP | $1,998,000 | -1.8% | 200,000 | 0.0% | 0.09% | -18.3% | |
| EUCR | New | EUCRATES BIOMEDICAL ACQU COR | $1,996,000 | – | 200,000 | +100.0% | 0.09% | – |
| CHFWU | CONSONANCE HFW ACQUISITION Cunit 99/99/9999 | $1,952,000 | -6.8% | 200,000 | 0.0% | 0.09% | -23.0% | |
| CDAK | CODIAK BIOSCIENCES INC | $1,737,000 | -53.3% | 115,195 | 0.0% | 0.08% | -61.5% | |
| PMVP | PMV PHARMACEUTICALS INC | $1,645,000 | -46.5% | 50,000 | 0.0% | 0.07% | -55.8% | |
| ARYD | New | ARYA SCIENCES ACQU CORP IVcl a | $1,571,000 | – | 150,000 | +100.0% | 0.07% | – |
| RPTX | REPARE THERAPEUTICS INC | $1,535,000 | -10.5% | 50,000 | 0.0% | 0.07% | -26.1% | |
| FSII | New | FS DEVELOPMENT CORP II | $1,494,000 | – | 150,000 | +100.0% | 0.07% | – |
| MGTX | MEIRAGTX HLDGS PLC | $1,368,000 | -4.7% | 94,819 | 0.0% | 0.06% | -20.8% | |
| DFHTW | DEERFIELD HEALTHCARE TECH AC*w exp 07/16/202 | $1,212,000 | -22.3% | 100,000 | 0.0% | 0.05% | -35.7% | |
| TMPM | New | TURMERIC ACQUISITION CORPcl a | $977,000 | – | 100,000 | +100.0% | 0.04% | – |
| KNTE | KINNATE BIOPHARMA INC | $779,000 | -21.7% | 25,000 | 0.0% | 0.04% | -34.0% | |
| EUCRW | New | EUCRATES BIOMEDICAL ACQU COR*w exp 10/23/202 | $665,000 | – | 66,666 | +100.0% | 0.03% | – |
| LSAQ | Sell | LIFESCI ACQUISITION II CORP | $573,000 | -73.1% | 56,500 | -71.8% | 0.02% | -78.3% |
| OMEG | New | OMEGA ALPHA SPACcl a | $495,000 | – | 50,000 | +100.0% | 0.02% | – |
| FSTX | New | F-STAR THERAPEUTICS INC | $498,000 | – | 46,000 | +100.0% | 0.02% | – |
| MTCR | Sell | METACRINE INC | $386,000 | -85.3% | 62,207 | -81.3% | 0.02% | -87.9% |
| TMPMW | New | TURMERIC ACQUISITION CORP*w exp 10/08/202 | $326,000 | – | 33,333 | +100.0% | 0.01% | – |
| ASMB | Exit | ASSEMBLY BIOSCIENCES INCcall | $0 | – | -17,800 | -100.0% | -0.01% | – |
| SURF | Exit | SURFACE ONCOLOGY INC | $0 | – | -48,558 | -100.0% | -0.02% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS INcall | $0 | – | -25,300 | -100.0% | -0.03% | – |
| TMPMU | Exit | TURMERIC ACQUISITION CORPunit | $0 | – | -100,000 | -100.0% | -0.06% | – |
| STRO | Exit | SUTRO BIOPHARMA INC | $0 | – | -93,416 | -100.0% | -0.11% | – |
| EUCRU | Exit | EUCRATES BIOMEDICAL ACQU CORunit | $0 | – | -200,000 | -100.0% | -0.12% | – |
| GOSS | Exit | GOSSAMER BIO INC | $0 | – | -294,221 | -100.0% | -0.15% | – |
| GLPG | Exit | GALAPAGOS NVspon adr | $0 | – | -46,666 | -100.0% | -0.25% | – |
| PANAU | Exit | PANACEA ACQUISITION CORPunit 99/99/9999 | $0 | – | -390,000 | -100.0% | -0.27% | – |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -400,000 | -100.0% | -0.36% | – |
| DFHT | Exit | DEERFIELD HEALTHCARE TECH AC | $0 | – | -481,600 | -100.0% | -0.40% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -1,509,812 | -100.0% | -0.52% | – |
| VINC | Exit | VINCERA PHARMA INC | $0 | – | -480,505 | -100.0% | -0.54% | – |
| Exit | GOSSAMER BIO INCnote | $0 | – | -30,000,000 | -100.0% | -1.46% | – | |
| GERN | Exit | GERON CORP | $0 | – | -18,939,925 | -100.0% | -1.62% | – |
| BIIB | Exit | BIOGEN INCcall | $0 | – | -254,100 | -100.0% | -3.34% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-05-17
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.