$1.86 Billion is the total value of EcoR1 Capital, LLC's 67 reported holdings in Q4 2020. The portfolio turnover from Q3 2020 to Q4 2020 was 95.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XNCR | XENCOR INC | $198,389,000 | +12.5% | 4,547,072 | 0.0% | 10.66% | -15.2% | |
| RLAY | RELAY THERAPEUTICS INC | $133,019,000 | -2.4% | 3,200,649 | 0.0% | 7.15% | -26.4% | |
| STTK | New | SHATTUCK LABS INC | $128,764,000 | – | 2,456,854 | +100.0% | 6.92% | – |
| SBTX | New | SILVERBACK THERAPEUTICS INC | $117,409,000 | – | 2,533,635 | +100.0% | 6.31% | – |
| PRTA | PROTHENA CORP PLC | $113,214,000 | +20.2% | 9,426,640 | 0.0% | 6.09% | -9.4% | |
| ORIC | Buy | ORIC PHARMACEUTICALS INC | $104,672,000 | +58.4% | 3,092,218 | +17.0% | 5.63% | +19.4% |
| MRTX | MIRATI THERAPEUTICS INC | $101,978,000 | +32.3% | 464,298 | 0.0% | 5.48% | -0.3% | |
| MORF | MORPHIC HLDG INC | $95,278,000 | +22.7% | 2,839,884 | 0.0% | 5.12% | -7.5% | |
| ANAB | ANAPTYSBIO INC | $69,301,000 | +45.8% | 3,223,324 | 0.0% | 3.72% | +9.9% | |
| BIIB | New | BIOGEN INCcall | $62,219,000 | – | 254,100 | +100.0% | 3.34% | – |
| SLDB | New | SOLID BIOSCIENCES INC | $60,471,000 | – | 7,977,702 | +100.0% | 3.25% | – |
| KURA | Sell | KURA ONCOLOGY INC | $57,907,000 | -59.0% | 1,773,037 | -61.5% | 3.11% | -69.1% |
| RCUS | Buy | ARCUS BIOSCIENCES INC | $57,005,000 | +83.8% | 2,195,892 | +21.3% | 3.06% | +38.5% |
| RNA | AVIDITY BIOSCIENCES INC | $53,693,000 | -9.3% | 2,103,950 | 0.0% | 2.89% | -31.7% | |
| NRIX | Buy | NURIX THERAPEUTICS INC | $50,767,000 | +22.0% | 1,544,019 | +29.5% | 2.73% | -8.0% |
| NLTX | Sell | NEOLEUKIN THERAPEUTICS INC | $44,030,000 | -5.0% | 3,122,704 | -19.2% | 2.37% | -28.4% |
| BCEL | ATRECA INC | $39,191,000 | +15.6% | 2,426,685 | 0.0% | 2.11% | -12.8% | |
| AKUS | AKOUOS INC | $39,184,000 | -13.3% | 1,975,984 | 0.0% | 2.11% | -34.6% | |
| AMTI | APPLIED MOLECULAR TRANS INC | $35,386,000 | -3.3% | 1,150,000 | 0.0% | 1.90% | -27.1% | |
| GERN | Sell | GERON CORP | $30,114,000 | -10.0% | 18,939,925 | -1.5% | 1.62% | -32.1% |
| New | GOSSAMER BIO INCnote | $27,175,000 | – | 30,000,000 | +100.0% | 1.46% | – | |
| KDNY | New | CHINOOK THERAPEUTICS INC | $19,825,000 | – | 1,250,001 | +100.0% | 1.07% | – |
| ALVR | ALLOVIR INC | $17,183,000 | +39.8% | 447,012 | 0.0% | 0.92% | +5.4% | |
| GRTS | New | GRITSTONE ONCOLOGY INC | $13,480,000 | – | 3,421,287 | +100.0% | 0.72% | – |
| ACIU | New | AC IMMUNE SA | $12,461,000 | – | 2,410,240 | +100.0% | 0.67% | – |
| KRON | New | KRONOS BIO INC | $11,570,000 | – | 387,357 | +100.0% | 0.62% | – |
| SYRS | New | SYROS PHARMACEUTICALS INC | $10,850,000 | – | 1,000,000 | +100.0% | 0.58% | – |
| VINC | New | VINCERA PHARMA INC | $10,047,000 | – | 480,505 | +100.0% | 0.54% | – |
| ACRS | Sell | ACLARIS THERAPEUTICS INC | $9,768,000 | +148.2% | 1,509,812 | -1.4% | 0.52% | +86.8% |
| ALPN | ALPINE IMMUNE SCIENCES INC | $9,340,000 | +43.3% | 741,290 | 0.0% | 0.50% | +8.0% | |
| BCTG | BCTG ACQUISITION CORP | $9,152,000 | +10.4% | 800,000 | 0.0% | 0.49% | -16.8% | |
| ITOS | ITEOS THERAPEUTICS INC | $8,793,000 | +37.1% | 260,000 | 0.0% | 0.47% | +3.5% | |
| DFHT | New | DEERFIELD HEALTHCARE TECH AC | $7,513,000 | – | 481,600 | +100.0% | 0.40% | – |
| CERE | New | CEREVEL THERAPEUTICS HLDNG I | $6,632,000 | – | 400,000 | +100.0% | 0.36% | – |
| CCCC | New | C4 THERAPEUTICS INC | $6,626,000 | – | 200,000 | +100.0% | 0.36% | – |
| KYMR | KYMERA THERAPEUTICS INC | $6,200,000 | +91.9% | 100,000 | 0.0% | 0.33% | +44.8% | |
| LOGC | New | LOGICBIO THERAPEUTICS INC | $5,913,000 | – | 775,000 | +100.0% | 0.32% | – |
| JYAC | New | JIYA ACQUISITION CORP | $5,150,000 | – | 500,000 | +100.0% | 0.28% | – |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 ORD | $5,124,000 | +16.5% | 400,000 | 0.0% | 0.28% | -12.4% | |
| PANAU | PANACEA ACQUISITION CORPunit 99/99/9999 | $4,977,000 | +6.3% | 390,000 | 0.0% | 0.27% | -19.8% | |
| CYCN | Sell | CYCLERION THERAPEUTICS INC | $4,915,000 | -70.5% | 1,606,276 | -41.4% | 0.26% | -77.8% |
| GLPG | New | GALAPAGOS NVspon adr | $4,619,000 | – | 46,666 | +100.0% | 0.25% | – |
| DYN | DYNE THERAPEUTICS INC | $4,515,000 | +4.0% | 215,000 | 0.0% | 0.24% | -21.6% | |
| NGM | New | NGM BIOPHARMACEUTICALS INC | $4,349,000 | – | 143,567 | +100.0% | 0.23% | – |
| CDAK | New | CODIAK BIOSCIENCES INC | $3,721,000 | – | 115,195 | +100.0% | 0.20% | – |
| VINCW | New | VINCERA PHARMA INC*w exp | $3,137,000 | – | 150,000 | +100.0% | 0.17% | – |
| PMVP | PMV PHARMACEUTICALS INC | $3,076,000 | +73.3% | 50,000 | 0.0% | 0.16% | +29.9% | |
| GOSS | New | GOSSAMER BIO INC | $2,845,000 | – | 294,221 | +100.0% | 0.15% | – |
| MTCR | METACRINE INC | $2,620,000 | -23.0% | 333,332 | 0.0% | 0.14% | -42.0% | |
| HLXA | New | HELIX ACQUISITION CORP | $2,274,000 | – | 200,000 | +100.0% | 0.12% | – |
| BLSA | New | BCLS ACQUISITION CORP | $2,228,000 | – | 200,000 | +100.0% | 0.12% | – |
| LSAQ | New | LIFESCI ACQUISITION II CORP | $2,134,000 | – | 200,000 | +100.0% | 0.12% | – |
| EUCRU | New | EUCRATES BIOMEDICAL ACQU CORunit | $2,132,000 | – | 200,000 | +100.0% | 0.12% | – |
| CHFWU | New | CONSONANCE HFW ACQUISITION Cunit | $2,094,000 | – | 200,000 | +100.0% | 0.11% | – |
| FLACU | New | FRAZIER LIFESCIENCES ACQU COunit | $2,076,000 | – | 200,000 | +100.0% | 0.11% | – |
| STRO | Sell | SUTRO BIOPHARMA INC | $2,028,000 | -93.5% | 93,416 | -97.0% | 0.11% | -95.1% |
| FVAM | New | 5 01 ACQUISITION CORP | $2,034,000 | – | 200,000 | +100.0% | 0.11% | – |
| RPTX | REPARE THERAPEUTICS INC | $1,715,000 | +11.4% | 50,000 | 0.0% | 0.09% | -16.4% | |
| BCAB | New | BIOATLA INC | $1,701,000 | – | 50,000 | +100.0% | 0.09% | – |
| DFHTW | New | DEERFIELD HEALTHCARE TECH AC*w exp | $1,560,000 | – | 100,000 | +100.0% | 0.08% | – |
| MGTX | MEIRAGTX HLDGS PLC | $1,436,000 | +14.4% | 94,819 | 0.0% | 0.08% | -13.5% | |
| TMPMU | New | TURMERIC ACQUISITION CORPunit | $1,027,000 | – | 100,000 | +100.0% | 0.06% | – |
| KNTE | New | KINNATE BIOPHARMA INC | $995,000 | – | 25,000 | +100.0% | 0.05% | – |
| ICPT | INTERCEPT PHARMACEUTICALS INcall | $625,000 | -40.4% | 25,300 | 0.0% | 0.03% | -54.7% | |
| SURF | Sell | SURFACE ONCOLOGY INC | $449,000 | -98.0% | 48,558 | -98.5% | 0.02% | -98.5% |
| ASMB | ASSEMBLY BIOSCIENCES INCcall | $108,000 | -63.1% | 17,800 | 0.0% | 0.01% | -71.4% | |
| SVRA | Exit | SAVARA INC | $0 | – | -56,500 | -100.0% | -0.00% | – |
| XOMA | Exit | XOMA CORP DEL | $0 | – | -50,809 | -100.0% | -0.07% | – |
| UBX | Exit | UNITY BIOTECHNOLOGY INC | $0 | – | -296,000 | -100.0% | -0.07% | – |
| FPRX | Exit | FIVE PRIME THERAPEUTICS INC | $0 | – | -379,945 | -100.0% | -0.13% | – |
| XCUR | Exit | EXICURE INC | $0 | – | -1,017,801 | -100.0% | -0.13% | – |
| RPRX | Exit | ROYALTY PHARMA PLC | $0 | – | -50,000 | -100.0% | -0.15% | – |
| GLYC | Exit | GLYCOMIMETICS INCcall | $0 | – | -850,000 | -100.0% | -0.19% | – |
| FSDC | Exit | FS DEV CORP | $0 | – | -350,000 | -100.0% | -0.28% | – |
| IRWD | Exit | IRONWOOD PHARMACEUTICALS INCcall | $0 | – | -500,000 | -100.0% | -0.32% | – |
| DFHTU | Exit | DEERFIELD HEALTHCARE TECH ACunit 07/16/2025 | $0 | – | -500,000 | -100.0% | -0.38% | – |
| LSAC | Exit | LIFESCI ACQUISITION CORP*w exp 02/14/202 | $0 | – | -630,505 | -100.0% | -0.56% | – |
| CNST | Exit | CONSTELLATION PHARMCETICLS Icall | $0 | – | -400,000 | -100.0% | -0.58% | – |
| GLYC | Exit | GLYCOMIMETICS INC | $0 | – | -3,725,150 | -100.0% | -0.82% | – |
| Exit | GOSSAMER BIO INCnote | $0 | – | -30,000,000 | -100.0% | -2.21% | – | |
| ASMB | Exit | ASSEMBLY BIOSCIENCES INC | $0 | – | -2,548,382 | -100.0% | -2.99% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-02-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.