$4.34 Billion is the total value of RTW INVESTMENTS, LP's 86 reported holdings in Q3 2022. The portfolio turnover from Q2 2022 to Q3 2022 was 27.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ALNY | ALNYLAM PHARMACEUTICALS INC | $336,942,000 | +37.2% | 1,683,362 | 0.0% | 7.77% | +22.5% | |
| PTCT | Buy | PTC THERAPEUTICS INC | $282,153,000 | +39.6% | 5,620,580 | +11.4% | 6.50% | +24.6% |
| RCKT | ROCKET PHARMACEUTICALS INC | $252,213,000 | +16.0% | 15,802,802 | 0.0% | 5.82% | +3.5% | |
| TMO | THERMO FISHER SCIENTIFIC INC | $220,881,000 | -6.6% | 435,500 | 0.0% | 5.09% | -16.7% | |
| IMCR | Buy | IMMUNOCORE HLDGS PLCads | $208,953,000 | +40.1% | 4,451,483 | +11.4% | 4.82% | +25.1% |
| MASI | Buy | MASIMO CORP | $203,269,000 | +15.1% | 1,439,993 | +6.6% | 4.69% | +2.7% |
| RXDX | PROMETHEUS BIOSCIENCES INC | $188,219,000 | +109.0% | 3,189,605 | 0.0% | 4.34% | +86.5% | |
| ARGX | Buy | ARGENX SEsponsored adr | $164,943,000 | -1.6% | 467,195 | +5.5% | 3.80% | -12.2% |
| PEN | PENUMBRA INC | $132,411,000 | +52.3% | 698,371 | 0.0% | 3.05% | +35.9% | |
| MRTX | MIRATI THERAPEUTICS INC | $131,485,000 | +4.0% | 1,882,663 | 0.0% | 3.03% | -7.2% | |
| ESTA | ESTABLISHMENT LABS HLDGS INC | $129,379,000 | +0.4% | 2,369,138 | 0.0% | 2.98% | -10.4% | |
| CYTK | Buy | CYTOKINETICS INC | $124,720,000 | +23.9% | 2,574,198 | +0.5% | 2.88% | +10.6% |
| ILMN | ILLUMINA INC | $107,677,000 | +3.5% | 564,375 | 0.0% | 2.48% | -7.7% | |
| RLMD | Buy | RELMADA THERAPEUTICS INC | $97,898,000 | +95.5% | 2,644,475 | +0.3% | 2.26% | +74.4% |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $97,727,000 | +19.3% | 2,359,996 | +71.9% | 2.25% | +6.4% |
| NTRA | Buy | NATERA INC | $96,811,000 | +28.7% | 2,209,283 | +4.1% | 2.23% | +14.9% |
| CLDX | CELLDEX THERAPEUTICS INC NEW | $86,697,000 | +4.3% | 3,084,215 | 0.0% | 2.00% | -6.9% | |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $84,439,000 | +21.2% | 5,170,784 | +7.8% | 1.95% | +8.2% |
| AXSM | Buy | AXSOME THERAPEUTICS INC | $83,982,000 | +35.5% | 1,882,164 | +16.3% | 1.94% | +20.8% |
| CUTR | CUTERA INC | $80,730,000 | +21.6% | 1,770,400 | 0.0% | 1.86% | +8.5% | |
| VCEL | Sell | VERICEL CORP | $71,918,000 | -18.9% | 3,099,904 | -12.0% | 1.66% | -27.7% |
| ISEE | New | IVERIC BIO INC | $65,033,000 | – | 3,625,000 | +100.0% | 1.50% | – |
| AXNX | Sell | AXONICS INC | $62,338,000 | -6.8% | 884,974 | -25.0% | 1.44% | -16.8% |
| ACET | Buy | ADICET BIO INC | $60,314,000 | +4.6% | 4,241,472 | +7.3% | 1.39% | -6.8% |
| ACAD | Sell | ACADIA PHARMACEUTICALS INC | $60,057,000 | +0.9% | 3,670,938 | -13.1% | 1.38% | -9.9% |
| VENTYX BIOSCIENCES INC | $54,173,000 | +185.5% | 1,551,778 | 0.0% | 1.25% | +154.9% | ||
| PMVP | Sell | PMV PHARMACEUTICALS INC | $51,847,000 | -17.2% | 4,356,920 | -0.9% | 1.20% | -26.1% |
| RGNX | REGENXBIO INC | $48,773,000 | +7.0% | 1,845,366 | 0.0% | 1.12% | -4.6% | |
| STOK | STOKE THERAPEUTICS INC | $46,889,000 | -2.8% | 3,651,823 | 0.0% | 1.08% | -13.2% | |
| CINCOR PHARMA INC | $45,610,000 | +74.2% | 1,389,705 | 0.0% | 1.05% | +55.6% | ||
| GMED | Sell | GLOBUS MED INCcl a | $44,540,000 | -29.3% | 747,685 | -33.3% | 1.03% | -36.9% |
| MIST | MILESTONE PHARMACEUTICALS IN | $39,656,000 | +49.4% | 4,315,102 | 0.0% | 0.91% | +33.2% | |
| GH | Sell | GUARDANT HEALTH INC | $39,074,000 | +4.7% | 725,887 | -21.5% | 0.90% | -6.5% |
| PTGX | Sell | PROTAGONIST THERAPEUTICS INC | $35,211,000 | -7.2% | 4,176,837 | -12.9% | 0.81% | -17.1% |
| TARS | Buy | TARSUS PHARMACEUTICALS INC | $34,637,000 | +17.8% | 2,023,179 | +0.5% | 0.80% | +5.1% |
| FULC | Buy | FULCRUM THERAPEUTICS INC | $32,246,000 | +66.1% | 3,985,910 | +0.6% | 0.74% | +48.3% |
| BCYC | BICYCLE THERAPEUTICS PLCsponsored ads | $29,686,000 | +38.6% | 1,276,276 | 0.0% | 0.68% | +23.7% | |
| AVDL | AVADEL PHARMACEUTICALS PLCsponsored adr | $28,767,000 | +105.3% | 5,741,939 | 0.0% | 0.66% | +83.1% | |
| GHRS | GH RESEARCH PLCordinary shares | $25,203,000 | +16.4% | 2,168,957 | 0.0% | 0.58% | +3.9% | |
| CCCC | Sell | C4 THERAPEUTICS INC | $24,727,000 | +6.0% | 2,819,472 | -8.9% | 0.57% | -5.5% |
| TXG | Sell | 10X GENOMICS INC | $18,217,000 | -58.0% | 639,654 | -33.3% | 0.42% | -62.6% |
| 2SEVENTY BIO INC | $17,889,000 | +10.2% | 1,229,508 | 0.0% | 0.41% | -1.7% | ||
| TNDM | Sell | TANDEM DIABETES CARE INC | $15,408,000 | -71.8% | 322,000 | -65.1% | 0.36% | -74.8% |
| APYX | APYX MEDICAL CORPORATION | $15,258,000 | -23.4% | 3,398,279 | 0.0% | 0.35% | -31.7% | |
| OM | OUTSET MED INC | $14,491,000 | +7.2% | 909,652 | 0.0% | 0.33% | -4.3% | |
| CSTL | Sell | CASTLE BIOSCIENCES INC | $13,483,000 | -32.8% | 516,995 | -43.4% | 0.31% | -40.0% |
| DERMTECH INC | $12,350,000 | -28.5% | 3,118,666 | 0.0% | 0.28% | -36.1% | ||
| OLK | Sell | OLINK HLDG ABsponsored ads | $11,920,000 | -49.8% | 981,918 | -37.1% | 0.28% | -55.2% |
| JNCE | Buy | JOUNCE THERAPEUTICS INC | $11,949,000 | -9.5% | 5,106,341 | +17.2% | 0.28% | -19.4% |
| New | THIRD HARMONIC BIO INC | $11,566,000 | – | 609,687 | +100.0% | 0.27% | – | |
| OYST | Sell | OYSTER PT PHARMA INC | $11,489,000 | +28.9% | 2,044,312 | -0.7% | 0.26% | +15.2% |
| AADI BIOSCIENCE INC | $10,805,000 | +14.7% | 764,701 | 0.0% | 0.25% | +2.5% | ||
| ALLK | New | ALLAKOS INC | $10,058,000 | – | 1,643,500 | +100.0% | 0.23% | – |
| GLUE | MONTE ROSA THERAPEUTICS INC | $9,923,000 | -15.5% | 1,214,572 | 0.0% | 0.23% | -24.4% | |
| HSAQ | New | HEALTH SCIENCES ACQ CORP 2 | $9,900,000 | – | 1,000,000 | +100.0% | 0.23% | – |
| IMUX | IMMUNIC INC | $8,728,000 | -8.9% | 2,761,968 | 0.0% | 0.20% | -19.0% | |
| LUNG | Sell | PULMONX CORP | $7,678,000 | -24.5% | 460,847 | -33.3% | 0.18% | -32.7% |
| RENOVACOR INC | $7,562,000 | +24.3% | 3,000,803 | 0.0% | 0.17% | +10.8% | ||
| TENAYA THERAPEUTICS INC | $7,130,000 | -48.5% | 2,458,750 | 0.0% | 0.16% | -54.2% | ||
| URGN | UROGEN PHARMA LTD | $7,134,000 | +1.6% | 857,464 | 0.0% | 0.16% | -9.4% | |
| Buy | SCIENCE 37 HOLDINGS INC | $6,969,000 | -19.1% | 4,328,387 | +1.0% | 0.16% | -27.8% | |
| RACB | RESEARCH ALLIANCE CORP II | $6,262,000 | +0.6% | 637,000 | 0.0% | 0.14% | -10.6% | |
| BLSA | BCLS ACQUISITION CORP | $6,137,000 | +1.2% | 612,500 | 0.0% | 0.14% | -10.2% | |
| BWAY | BRAINSWAY LTDsponsored ads | $5,785,000 | -25.3% | 1,602,381 | 0.0% | 0.13% | -33.5% | |
| AKYA | Buy | AKOYA BIOSCIENCES INC | $5,685,000 | +89.4% | 483,815 | +107.2% | 0.13% | +67.9% |
| MASS | Sell | 908 DEVICES INC | $5,132,000 | -51.4% | 312,000 | -39.2% | 0.12% | -56.8% |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $4,955,000 | +1.0% | 500,000 | 0.0% | 0.11% | -10.2% | |
| SMIHU | SUMMIT HEALTHCRE ACQUISTN COunit 06/03/2026 | $4,925,000 | +1.0% | 500,000 | 0.0% | 0.11% | -9.5% | |
| ARYA SCIENCES ACQUISITN CORP | $4,900,000 | +0.8% | 500,000 | 0.0% | 0.11% | -10.3% | ||
| Sell | SIGHT SCIENCES INC | $4,225,000 | -52.9% | 665,323 | -33.3% | 0.10% | -58.2% | |
| FVAM | 5 01 ACQUISITION CORP | $3,920,000 | +1.1% | 392,000 | 0.0% | 0.09% | -10.0% | |
| MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $3,880,000 | +47.8% | 500,000 | 0.0% | 0.09% | +30.9% | ||
| IMTX | IMMATICS N.V | $3,500,000 | +14.8% | 350,000 | 0.0% | 0.08% | +2.5% | |
| TELA | Sell | TELA BIO INC | $3,326,000 | -53.4% | 390,364 | -61.6% | 0.08% | -58.2% |
| MSAC | MEDICUS SCIENCES ACQUISITION | $2,970,000 | +1.2% | 300,000 | 0.0% | 0.07% | -10.5% | |
| JNJ | JOHNSON & JOHNSON | $2,961,000 | -8.0% | 18,127 | 0.0% | 0.07% | -18.1% | |
| XGN | Buy | EXAGEN INC | $2,842,000 | -51.7% | 1,048,662 | +2.3% | 0.07% | -56.6% |
| LABP | Sell | LANDOS BIOPHARMA INC | $2,584,000 | -17.0% | 3,975,722 | -7.0% | 0.06% | -25.0% |
| ROIVANT SCIENCES LTD | $2,585,000 | -20.9% | 802,717 | 0.0% | 0.06% | -28.6% | ||
| EPIX | Sell | ESSA PHARMA INC | $2,387,000 | -71.3% | 1,311,294 | -50.3% | 0.06% | -74.4% |
| NYXOAH S A | $2,173,000 | -31.5% | 344,911 | 0.0% | 0.05% | -39.0% | ||
| ASLN | Sell | ASLAN PHARMACEUTICALS LTDads | $1,806,000 | +12.2% | 3,015,987 | -7.2% | 0.04% | 0.0% |
| NAUT | Sell | NAUTILUS BIOTECHNOLOGY INC | $1,272,000 | -57.0% | 600,000 | -45.5% | 0.03% | -61.8% |
| MIRO | MIROMATRIX MED INC | $1,226,000 | +9.8% | 280,000 | 0.0% | 0.03% | -3.4% | |
| RENOVACOR INC*w exp 99/99/999 | $28,000 | +33.3% | 350,000 | 0.0% | 0.00% | 0.0% | ||
| MSACW | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $1,000 | -83.3% | 33,331 | 0.0% | 0.00% | – | |
| DNAY | Exit | CODEX DNA INC | $0 | – | -100,000 | -100.0% | -0.01% | – |
| Exit | MINERVA SURGICAL INC | $0 | – | -166,000 | -100.0% | -0.01% | – | |
| OMIC | Exit | SINGULAR GENOMICS SYSTEMS IN | $0 | – | -100,000 | -100.0% | -0.01% | – |
| RCEL | Exit | AVITA MEDICAL INC | $0 | – | -106,667 | -100.0% | -0.01% | – |
| Exit | ISOPLEXIS CORP | $0 | – | -365,000 | -100.0% | -0.02% | – | |
| APEN | Exit | APOLLO ENDOSURGERY INC | $0 | – | -258,064 | -100.0% | -0.02% | – |
| Exit | PYXIS ONCOLOGY INC | $0 | – | -682,220 | -100.0% | -0.04% | – | |
| GTH | Exit | GENETRON HLDGS LTDads | $0 | – | -1,198,961 | -100.0% | -0.05% | – |
| Exit | RXSIGHT INC | $0 | – | -150,000 | -100.0% | -0.06% | – | |
| CTIC | Exit | CTI BIOPHARMA CORP | $0 | – | -471,630 | -100.0% | -0.07% | – |
| AGEN | Exit | AGENUS INC | $0 | – | -1,583,822 | -100.0% | -0.08% | – |
| PNT | Exit | POINT BIOPHARMA GLOBAL INC | $0 | – | -490,000 | -100.0% | -0.09% | – |
| Exit | MAXCYTE INC | $0 | – | -772,735 | -100.0% | -0.09% | – | |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -2,849,707 | -100.0% | -0.14% | – |
| Exit | PROCEPT BIOROBOTICS CORP | $0 | – | -161,138 | -100.0% | -0.14% | – | |
| LJPC | Exit | LA JOLLA PHARMACEUTICAL CO | $0 | – | -2,327,403 | -100.0% | -0.19% | – |
| TWST | Exit | TWIST BIOSCIENCE CORP | $0 | – | -270,000 | -100.0% | -0.24% | – |
| Exit | SOMALOGIC INC | $0 | – | -2,114,830 | -100.0% | -0.25% | – | |
| CDXS | Exit | CODEXIS INC | $0 | – | -920,448 | -100.0% | -0.25% | – |
| Exit | CYTEK BIOSCIENCES INC | $0 | – | -916,838 | -100.0% | -0.25% | – | |
| ALGN | Exit | ALIGN TECHNOLOGY INC | $0 | – | -42,000 | -100.0% | -0.26% | – |
| CYRX | Exit | CRYOPORT INC | $0 | – | -335,299 | -100.0% | -0.27% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -3,975,554 | -100.0% | -0.30% | – |
| VERU | Exit | VERU INC | $0 | – | -2,220,983 | -100.0% | -0.65% | – |
| QTRX | Exit | QUANTERIX CORP | $0 | – | -1,819,120 | -100.0% | -0.76% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC | 36 | Q3 2023 | 19.7% |
| MASIMO CORP | 32 | Q3 2023 | 5.8% |
| LA JOLLA PHARMACEUTICAL CO | 31 | Q2 2022 | 9.7% |
| REGENXBIO INC | 30 | Q4 2022 | 10.8% |
| AGENUS INC | 29 | Q2 2022 | 9.0% |
| PTC THERAPEUTICS INC | 28 | Q3 2023 | 12.8% |
| DICERNA PHARMACEUTICALS INC | 28 | Q3 2021 | 10.8% |
| MIRATI THERAPEUTICS INC | 26 | Q3 2023 | 6.2% |
| ARGENX SE | 26 | Q3 2023 | 5.3% |
| VERICEL CORP | 24 | Q3 2023 | 3.9% |
View RTW INVESTMENTS, LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ROCKET PHARMACEUTICALS, INC. | September 19, 2023 | 18,188,457 | - |
| ALLURION TECHNOLOGIES, INC. | August 11, 2023 | 3,457,707 | 7.4% |
| Orchestra BioMed Holdings, Inc. | May 05, 2023 | 5,620,645 | 15.7% |
| Renovacor, Inc.Sold out | April 05, 2023 | 0 | - |
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Aptevo Therapeutics Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ASLAN Pharmaceuticals LtdSold out | February 14, 2023 | 0 | 0.0% |
| Athira Pharma, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| BELLUS Health Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Clearside Biomedical, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
View RTW INVESTMENTS, LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-03-01 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View RTW INVESTMENTS, LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.