$3.87 Billion is the total value of RTW INVESTMENTS, LP's 107 reported holdings in Q2 2022. The portfolio turnover from Q1 2022 to Q2 2022 was 17.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ALNY | ALNYLAM PHARMACEUTICALS INC | $245,518,000 | -10.7% | 1,683,362 | 0.0% | 6.34% | +11.5% | |
| TMO | Buy | THERMO FISHER SCIENTIFIC INC | $236,598,000 | +7.4% | 435,500 | +16.8% | 6.11% | +34.1% |
| RCKT | ROCKET PHARMACEUTICALS INC | $217,447,000 | -13.2% | 15,802,802 | 0.0% | 5.62% | +8.3% | |
| PTCT | Sell | PTC THERAPEUTICS INC | $202,115,000 | +3.8% | 5,045,307 | -3.4% | 5.22% | +29.5% |
| MASI | Buy | MASIMO CORP | $176,534,000 | +7.6% | 1,350,993 | +19.8% | 4.56% | +34.3% |
| ARGX | Buy | ARGENX SEsponsored adr | $167,706,000 | +57.8% | 442,635 | +31.4% | 4.33% | +97.0% |
| IMCR | Buy | IMMUNOCORE HLDGS PLCads | $149,097,000 | +168.2% | 3,996,154 | +114.9% | 3.85% | +234.7% |
| ESTA | Buy | ESTABLISHMENT LABS HLDGS INC | $128,834,000 | -17.6% | 2,369,138 | +2.2% | 3.33% | +2.9% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $126,383,000 | -1.6% | 1,882,663 | +20.6% | 3.26% | +22.9% |
| ILMN | Buy | ILLUMINA INC | $104,048,000 | -41.5% | 564,375 | +10.8% | 2.69% | -27.0% |
| CYTK | CYTOKINETICS INC | $100,629,000 | +6.7% | 2,561,182 | 0.0% | 2.60% | +33.3% | |
| RXDX | Buy | PROMETHEUS BIOSCIENCES INC | $90,043,000 | -13.5% | 3,189,605 | +15.7% | 2.33% | +7.9% |
| VCEL | Sell | VERICEL CORP | $88,707,000 | -42.2% | 3,522,904 | -12.3% | 2.29% | -27.9% |
| PEN | Buy | PENUMBRA INC | $86,961,000 | -41.2% | 698,371 | +4.9% | 2.25% | -26.6% |
| CLDX | CELLDEX THERAPEUTICS INC NEW | $83,150,000 | -20.8% | 3,084,215 | 0.0% | 2.15% | -1.2% | |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | $81,930,000 | -17.8% | 1,373,284 | 0.0% | 2.12% | +2.6% | |
| NTRA | Buy | NATERA INC | $75,214,000 | -3.6% | 2,122,283 | +10.7% | 1.94% | +20.4% |
| RNA | AVIDITY BIOSCIENCES INC | $69,671,000 | -21.3% | 4,795,000 | 0.0% | 1.80% | -1.8% | |
| AXNX | Sell | AXONICS INC | $66,869,000 | -38.7% | 1,179,965 | -32.3% | 1.73% | -23.5% |
| CUTR | Buy | CUTERA INC | $66,390,000 | -37.0% | 1,770,400 | +16.0% | 1.72% | -21.3% |
| GMED | Sell | GLOBUS MED INCcl a | $62,963,000 | -49.3% | 1,121,527 | -33.3% | 1.63% | -36.7% |
| PMVP | Buy | PMV PHARMACEUTICALS INC | $62,638,000 | -22.3% | 4,395,677 | +13.5% | 1.62% | -3.1% |
| AXSM | AXSOME THERAPEUTICS INC | $62,001,000 | -7.5% | 1,618,819 | 0.0% | 1.60% | +15.5% | |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $59,518,000 | – | 4,224,109 | +100.0% | 1.54% | – |
| ACET | Buy | ADICET BIO INC | $57,689,000 | -3.4% | 3,951,281 | +32.2% | 1.49% | +20.6% |
| TNDM | Sell | TANDEM DIABETES CARE INC | $54,610,000 | -53.3% | 922,630 | -8.2% | 1.41% | -41.7% |
| RLMD | Buy | RELMADA THERAPEUTICS INC | $50,088,000 | -26.9% | 2,637,581 | +3.8% | 1.29% | -8.8% |
| STOK | Buy | STOKE THERAPEUTICS INC | $48,241,000 | -37.1% | 3,651,823 | +0.2% | 1.25% | -21.5% |
| RGNX | REGENXBIO INC | $45,581,000 | -25.6% | 1,845,366 | 0.0% | 1.18% | -7.1% | |
| TXG | Buy | 10X GENOMICS INC | $43,417,000 | -22.3% | 959,481 | +30.6% | 1.12% | -2.9% |
| PTGX | PROTAGONIST THERAPEUTICS INC | $37,924,000 | -66.6% | 4,794,499 | 0.0% | 0.98% | -58.3% | |
| GH | Buy | GUARDANT HEALTH INC | $37,310,000 | -18.4% | 924,887 | +34.1% | 0.96% | +1.9% |
| QTRX | Buy | QUANTERIX CORP | $29,452,000 | -19.2% | 1,819,120 | +45.7% | 0.76% | +0.9% |
| TARS | TARSUS PHARMACEUTICALS INC | $29,399,000 | -13.2% | 2,013,601 | 0.0% | 0.76% | +8.4% | |
| MIST | MILESTONE PHARMACEUTICALS IN | $26,538,000 | -4.2% | 4,315,102 | 0.0% | 0.69% | +19.7% | |
| CINCOR PHARMA INC | $26,182,000 | +7.4% | 1,389,705 | 0.0% | 0.68% | +34.1% | ||
| VERU | New | VERU INC | $25,097,000 | – | 2,220,983 | +100.0% | 0.65% | – |
| OLK | Buy | OLINK HLDG ABsponsored ads | $23,746,000 | +32.1% | 1,562,222 | +53.4% | 0.61% | +65.1% |
| CCCC | Sell | C4 THERAPEUTICS INC | $23,335,000 | -78.8% | 3,094,825 | -31.7% | 0.60% | -73.5% |
| GHRS | GH RESEARCH PLCordinary shares | $21,646,000 | -45.4% | 2,168,957 | 0.0% | 0.56% | -31.9% | |
| BCYC | BICYCLE THERAPEUTICS PLCsponsored ads | $21,416,000 | -61.8% | 1,276,276 | 0.0% | 0.55% | -52.3% | |
| CSTL | Buy | CASTLE BIOSCIENCES INC | $20,058,000 | -10.0% | 913,789 | +84.0% | 0.52% | +12.4% |
| APYX | APYX MEDICAL CORPORATION | $19,914,000 | -10.3% | 3,398,279 | 0.0% | 0.52% | +12.2% | |
| FULC | Buy | FULCRUM THERAPEUTICS INC | $19,410,000 | -77.3% | 3,961,194 | +9.7% | 0.50% | -71.7% |
| VENTYX BIOSCIENCES INC | $18,978,000 | -9.9% | 1,551,778 | 0.0% | 0.49% | +12.4% | ||
| DERMTECH INC | $17,277,000 | -62.3% | 3,118,666 | 0.0% | 0.45% | -53.0% | ||
| 2SEVENTY BIO INC | $16,230,000 | -22.6% | 1,229,508 | 0.0% | 0.42% | -3.5% | ||
| AVDL | AVADEL PHARMACEUTICALS PLCsponsored adr | $14,010,000 | -64.3% | 5,741,939 | 0.0% | 0.36% | -55.4% | |
| TENAYA THERAPEUTICS INC | $13,843,000 | -52.2% | 2,458,750 | 0.0% | 0.36% | -40.2% | ||
| OM | Buy | OUTSET MED INC | $13,517,000 | -66.9% | 909,652 | +1.1% | 0.35% | -58.7% |
| JNCE | Sell | JOUNCE THERAPEUTICS INC | $13,206,000 | -58.4% | 4,358,433 | -6.9% | 0.34% | -48.2% |
| MGNX | MACROGENICS INC | $11,728,000 | -66.5% | 3,975,554 | 0.0% | 0.30% | -58.2% | |
| GLUE | MONTE ROSA THERAPEUTICS INC | $11,745,000 | -31.0% | 1,214,572 | 0.0% | 0.30% | -13.9% | |
| MASS | Buy | 908 DEVICES INC | $10,562,000 | +1289.7% | 512,957 | +1182.4% | 0.27% | +1606.2% |
| CYRX | New | CRYOPORT INC | $10,388,000 | – | 335,299 | +100.0% | 0.27% | – |
| LUNG | Sell | PULMONX CORP | $10,175,000 | -48.6% | 691,255 | -13.4% | 0.26% | -35.9% |
| ALGN | New | ALIGN TECHNOLOGY INC | $9,940,000 | – | 42,000 | +100.0% | 0.26% | – |
| New | CYTEK BIOSCIENCES INC | $9,838,000 | – | 916,838 | +100.0% | 0.25% | – | |
| CDXS | New | CODEXIS INC | $9,628,000 | – | 920,448 | +100.0% | 0.25% | – |
| IMUX | Buy | IMMUNIC INC | $9,584,000 | -68.7% | 2,761,968 | +2.1% | 0.25% | -60.8% |
| New | SOMALOGIC INC | $9,559,000 | – | 2,114,830 | +100.0% | 0.25% | – | |
| TWST | New | TWIST BIOSCIENCE CORP | $9,439,000 | – | 270,000 | +100.0% | 0.24% | – |
| AADI BIOSCIENCES INC | $9,421,000 | -27.4% | 764,701 | 0.0% | 0.24% | -9.7% | ||
| SIGHT SCIENCES INC | $8,964,000 | -22.2% | 997,099 | 0.0% | 0.23% | -2.9% | ||
| OYST | OYSTER PT PHARMA INC | $8,913,000 | -62.8% | 2,058,504 | 0.0% | 0.23% | -53.6% | |
| Buy | SCIENCE 37 HOLDINGS INC | $8,618,000 | -60.1% | 4,287,546 | +6.1% | 0.22% | -50.1% | |
| EPIX | ESSA PHARMA INC | $8,307,000 | -49.0% | 2,637,192 | 0.0% | 0.22% | -36.2% | |
| BWAY | BRAINSWAY LTDsponsored ads | $7,740,000 | -44.7% | 1,602,381 | 0.0% | 0.20% | -31.0% | |
| LJPC | LA JOLLA PHARMACEUTICAL CO | $7,424,000 | -25.3% | 2,327,403 | 0.0% | 0.19% | -6.8% | |
| TELA | TELA BIO INC | $7,133,000 | -39.7% | 1,017,546 | 0.0% | 0.18% | -24.9% | |
| URGN | UROGEN PHARMA LTD | $7,023,000 | -6.0% | 857,464 | 0.0% | 0.18% | +16.8% | |
| RACB | RESEARCH ALLIANCE CORP II | $6,223,000 | +0.1% | 637,000 | 0.0% | 0.16% | +24.8% | |
| BLSA | BCLS ACQUISITION CORP | $6,064,000 | +0.3% | 612,500 | 0.0% | 0.16% | +25.6% | |
| RENOVACOR INC | $6,085,000 | -52.2% | 3,000,803 | 0.0% | 0.16% | -40.3% | ||
| XGN | Buy | EXAGEN INC | $5,884,000 | -26.0% | 1,025,002 | +3.5% | 0.15% | -7.9% |
| PROCEPT BIOROBOTICS CORP | $5,268,000 | -6.6% | 161,138 | 0.0% | 0.14% | +16.2% | ||
| CTMX | Sell | CYTOMX THERAPEUTICS INC | $5,215,000 | -66.2% | 2,849,707 | -50.7% | 0.14% | -57.7% |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $4,905,000 | +0.1% | 500,000 | 0.0% | 0.13% | +25.7% | |
| ARYA SCIENCES ACQUISITN CORP | $4,860,000 | +0.1% | 500,000 | 0.0% | 0.13% | +26.0% | ||
| SMIHU | SUMMIT HEALTHCRE ACQUISTN COunit 06/03/2026 | $4,875,000 | -0.3% | 500,000 | 0.0% | 0.13% | +24.8% | |
| FVAM | 5 01 ACQUISITION CORP | $3,877,000 | +0.4% | 392,000 | 0.0% | 0.10% | +25.0% | |
| Buy | MAXCYTE INC | $3,655,000 | +162.0% | 772,735 | +287.2% | 0.09% | +224.1% | |
| PNT | POINT BIOPHARMA GLOBAL INC | $3,337,000 | -14.5% | 490,000 | 0.0% | 0.09% | +6.2% | |
| ROIVANT SCIENCES LTD | $3,267,000 | -17.6% | 802,717 | 0.0% | 0.08% | +2.4% | ||
| JNJ | JOHNSON & JOHNSON | $3,218,000 | +0.2% | 18,127 | 0.0% | 0.08% | +25.8% | |
| NYXOAH S A | $3,173,000 | -51.9% | 344,911 | 0.0% | 0.08% | -40.1% | ||
| LABP | LANDOS BIOPHARMA INC | $3,112,000 | -50.7% | 4,275,722 | 0.0% | 0.08% | -38.9% | |
| AGEN | Sell | AGENUS INC | $3,073,000 | -65.1% | 1,583,822 | -55.8% | 0.08% | -56.6% |
| IMTX | IMMATICS N.V | $3,049,000 | +9.0% | 350,000 | 0.0% | 0.08% | +36.2% | |
| AKYA | Buy | AKOYA BIOSCIENCES INC | $3,001,000 | +251.4% | 233,557 | +200.7% | 0.08% | +333.3% |
| MSAC | MEDICUS SCIENCES ACQUISITION | $2,934,000 | 0.0% | 300,000 | 0.0% | 0.08% | +24.6% | |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | $2,959,000 | -38.0% | 1,100,000 | 0.0% | 0.08% | -23.2% | |
| CTIC | New | CTI BIOPHARMA CORP | $2,816,000 | – | 471,630 | +100.0% | 0.07% | – |
| New | MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $2,625,000 | – | 500,000 | +100.0% | 0.07% | – | |
| RXSIGHT INC | $2,112,000 | +13.7% | 150,000 | 0.0% | 0.06% | +44.7% | ||
| GTH | GENETRON HLDGS LTDads | $2,038,000 | -22.4% | 1,198,961 | 0.0% | 0.05% | -1.9% | |
| Sell | PYXIS ONCOLOGY INC | $1,624,000 | -81.0% | 682,220 | -67.8% | 0.04% | -76.3% | |
| ASLN | ASLAN PHARMACEUTICALS LTDads | $1,609,000 | -45.0% | 3,250,000 | 0.0% | 0.04% | -31.1% | |
| MIRO | MIROMATRIX MED INC | $1,117,000 | +0.7% | 280,000 | 0.0% | 0.03% | +26.1% | |
| APEN | APOLLO ENDOSURGERY INC | $942,000 | -39.7% | 258,064 | 0.0% | 0.02% | -25.0% | |
| ISOPLEXIS CORP | $788,000 | -37.1% | 365,000 | 0.0% | 0.02% | -23.1% | ||
| RCEL | AVITA MEDICAL INC | $507,000 | -44.0% | 106,667 | 0.0% | 0.01% | -31.6% | |
| OMIC | SINGULAR GENOMICS SYSTEMS IN | $382,000 | -39.5% | 100,000 | 0.0% | 0.01% | -23.1% | |
| MINERVA SURGICAL INC | $390,000 | -47.8% | 166,000 | 0.0% | 0.01% | -33.3% | ||
| DNAY | Sell | CODEX DNA INC | $180,000 | -83.2% | 100,000 | -50.0% | 0.01% | -77.3% |
| RENOVACOR INC*w exp 99/99/999 | $21,000 | -80.7% | 350,000 | 0.0% | 0.00% | -50.0% | ||
| MSACW | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $6,000 | -57.1% | 33,331 | 0.0% | 0.00% | – | |
| ZY | Exit | ZYMERGEN INC | $0 | – | -70,000 | -100.0% | -0.00% | – |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -223,725 | -100.0% | -0.01% | – |
| CNTB | Exit | CONNECT BIOPHARMA HLDGS LTDads | $0 | – | -446,564 | -100.0% | -0.03% | – |
| Exit | SOPHIA GENETICS SAordinary shares | $0 | – | -226,589 | -100.0% | -0.04% | – | |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -51,194 | -100.0% | -0.05% | – |
| PRQR | Exit | PROQR THRAPEUTICS N V | $0 | – | -7,019,610 | -100.0% | -0.13% | – |
| NSTG | Exit | NANOSTRING TECHNOLOGIES INC | $0 | – | -404,029 | -100.0% | -0.29% | – |
| ITOS | Exit | ITEOS THERAPEUTICS INC | $0 | – | -489,014 | -100.0% | -0.33% | – |
| ATHA | Exit | ATHIRA PHARMA INC | $0 | – | -1,906,557 | -100.0% | -0.53% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-08-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC | 36 | Q3 2023 | 19.7% |
| MASIMO CORP | 32 | Q3 2023 | 5.8% |
| LA JOLLA PHARMACEUTICAL CO | 31 | Q2 2022 | 9.7% |
| REGENXBIO INC | 30 | Q4 2022 | 10.8% |
| AGENUS INC | 29 | Q2 2022 | 9.0% |
| PTC THERAPEUTICS INC | 28 | Q3 2023 | 12.8% |
| DICERNA PHARMACEUTICALS INC | 28 | Q3 2021 | 10.8% |
| MIRATI THERAPEUTICS INC | 26 | Q3 2023 | 6.2% |
| ARGENX SE | 26 | Q3 2023 | 5.3% |
| VERICEL CORP | 24 | Q3 2023 | 3.9% |
View RTW INVESTMENTS, LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ROCKET PHARMACEUTICALS, INC. | September 19, 2023 | 18,188,457 | - |
| ALLURION TECHNOLOGIES, INC. | August 11, 2023 | 3,457,707 | 7.4% |
| Orchestra BioMed Holdings, Inc. | May 05, 2023 | 5,620,645 | 15.7% |
| Renovacor, Inc.Sold out | April 05, 2023 | 0 | - |
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Aptevo Therapeutics Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ASLAN Pharmaceuticals LtdSold out | February 14, 2023 | 0 | 0.0% |
| Athira Pharma, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| BELLUS Health Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Clearside Biomedical, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
View RTW INVESTMENTS, LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-03-01 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View RTW INVESTMENTS, LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.