RA Capital Management Q1 2021 13F Holdings

RA Capital Management Q1 2021 holdings
TickerName Value Shares↓ Weighting
ASND ASCENDIS PHARMA A/Ssponsored adrAdd  $826,408
-15.5%
6,412,228
9.3%
12.46%
-8.9%
NVAX NOVAVAX INCReduce  $544,308
28.8%
3,002,087
-20.8%
8.21%
39.0%
VOR VOR BIOPHARMA INCNew  $479,31411,120,9737.23%
AVIR ATEA PHARMACEUTICALS INC  $331,502
47.8%
5,368,4510.0%5.00%
59.5%
FMTX FORMA THERAPEUTICS HLD...  $252,506
-19.7%
9,011,6510.0%3.81%
-13.4%
TGTX TG THERAPEUTICS INCReduce  $223,462
-50.5%
4,636,146
-46.6%
3.37%
-46.6%
NKTX NKARTA INC  $184,409
-46.5%
5,605,1290.0%2.78%
-42.3%
CCXI CHEMOCENTRYX INCReduce  $182,251
-38.4%
3,556,810
-25.5%
2.75%
-33.5%
MGNX MACROGENICS INCAdd  $157,135
57.1%
4,933,594
12.8%
2.37%
69.5%
ITOS ITEOS THERAPEUTICS INC  $150,982
1.1%
4,417,2580.0%2.28%
9.1%
IMGN IMMUNOGEN INC  $149,181
25.6%
18,417,4580.0%2.25%
35.4%
TVTX TRAVERE THERAPEUTICS INCAdd  $140,192
12.9%
5,614,428
23.2%
2.11%
21.7%
INSTIL BIO INCNew  $122,1594,870,7931.84%
PHAT PHATHOM PHARMACEUTICAL...Reduce  $117,000
-7.9%
3,115,008
-18.6%
1.76%
-0.7%
ETNB 89BIO INC  $112,154
-2.8%
4,736,2140.0%1.69%
4.8%
KNTE KINNATE BIOPHARMA INC  $111,960
-21.7%
3,593,0520.0%1.69%
-15.5%
RYTM RHYTHM PHARMACEUTICALS...Add  $103,608
-16.6%
4,871,067
16.6%
1.56%
-10.1%
ZGNX ZOGENIX INCReduce  $103,143
-3.5%
5,283,976
-1.2%
1.56%
4.1%
AXSM AXSOME THERAPEUTICS INC  $93,731
-30.5%
1,655,4470.0%1.41%
-25.0%
RCKT ROCKET PHARMACEUTICALS...Reduce  $93,494
-20.2%
2,107,149
-1.4%
1.41%
-13.9%
ADVM ADVERUM BIOTECHNOLOGIE...Reduce  $92,347
-10.3%
9,365,833
-1.4%
1.39%
-3.3%
EDGEWISE THERAPEUTICS INCNew  $84,9432,613,6231.28%
CRIS CURIS INCReduce  $80,826
28.0%
7,140,091
-7.4%
1.22%
38.2%
BOLT BOLT BIOTHERAPEUTICS INCNew  $78,2712,378,3251.18%
PCVX VAXCYTE INCAdd  $76,350
-22.6%
3,865,808
4.2%
1.15%
-16.5%
MCRB SERES THERAPEUTICS INCNew  $76,0633,694,1931.15%
SBTX SILVERBACK THERAPEUTIC...  $76,012
-5.8%
1,742,1860.0%1.15%
1.5%
IGMS IGM BIOSCIENCES INC  $75,365
-13.1%
982,7230.0%1.14%
-6.3%
KALA KALA PHARMACEUTICALS INC  $73,295
-0.6%
10,874,6130.0%1.10%
7.2%
OLMA OLEMA PHARMACEUTICALS INC  $71,350
-31.0%
2,150,4040.0%1.08%
-25.5%
ORTX ORCHARD THERAPEUTICS PLCads  $69,164
68.1%
12,315,2130.0%1.04%
81.4%
SLDB SOLID BIOSCIENCES INCAdd  $68,394
-9.6%
12,367,873
24.0%
1.03%
-2.5%
DESIGN THERAPEUTICS INCNew  $65,3802,186,6360.99%
BDTX BLACK DIAMOND THERAPEU...  $62,831
-24.3%
2,589,9040.0%0.95%
-18.4%
TRILLIUM THERAPEUTICS INC  $56,820
-27.0%
5,290,4810.0%0.86%
-21.2%
PMVP PMV PHARMACEUTICALS INC  $56,251
-46.5%
1,710,2650.0%0.85%
-42.4%
CONNECT BIOPHARMA HLDG...adsNew  $55,3372,991,2080.83%
CNST CONSTELLATION PHARMCET...Add  $52,359
-1.9%
2,238,536
20.8%
0.79%
5.9%
CCCC C4 THERAPEUTICS INC  $50,956
11.7%
1,377,5690.0%0.77%
20.4%
STRO SUTRO BIOPHARMA INC  $48,211
4.8%
2,118,2120.0%0.73%
13.1%
GERN GERON CORP  $47,600
-0.6%
30,126,2990.0%0.72%
7.2%
WVE WAVE LIFE SCIENCES LTD  $43,619
-28.7%
7,775,2070.0%0.66%
-23.0%
DYN DYNE THERAPEUTICS INC  $43,562
-26.0%
2,805,0450.0%0.66%
-20.2%
VRNA VERONA PHARMA PLCsponsored ads  $42,636
34.0%
5,100,0000.0%0.64%
44.5%
ARDX ARDELYX INCReduce  $40,232
0.9%
6,077,294
-1.4%
0.61%
9.0%
INZY INOZYME PHARMA INC  $39,672
-4.1%
2,003,6530.0%0.60%
3.5%
STSA SATSUMA PHARMACEUTICAL...Add  $34,953
61.9%
5,914,252
26.3%
0.53%
74.5%
RLAY RELAY THERAPEUTICS INC  $34,570
-16.8%
1,000,0000.0%0.52%
-10.3%
AKUS AKOUOS INC  $31,641
-30.1%
2,281,2490.0%0.48%
-24.5%
CERE CEREVEL THERAPEUTICS H...  $30,206
-17.2%
2,200,0000.0%0.46%
-10.8%
CTMX CYTOMX THERAPEUTICS INCNew  $27,0553,500,0000.41%
ACHILLES THERAPEUTICS PLCsponsored adsNew  $22,9861,388,8880.35%
SNDX SYNDAX PHARMACEUTICALS...  $22,876
0.5%
1,023,0670.0%0.34%
8.5%
LRMR LARIMAR THERAPEUTICS INC  $22,136
-31.8%
1,515,1510.0%0.33%
-26.3%
IKENA ONCOLOGY INCNew  $21,188750,0000.32%
SCPH SCPHARMACEUTICALS INCReduce  $18,162
-2.4%
2,731,170
-22.4%
0.27%
5.4%
CNCE CONCERT PHARMACEUTICAL...Add  $15,138
-34.3%
3,033,603
66.4%
0.23%
-29.2%
CGEM CULLINAN ONCOLOGY INC COMNew  $14,585350,0000.22%
ORIC ORIC PHARMACEUTICALS INC  $14,308
-27.6%
584,0000.0%0.22%
-21.7%
PRQR PROQR THERAPEUTICS N VNew  $13,9982,117,6690.21%
BCTG BCTG ACQUISITION CORP  $13,900
-2.8%
1,250,0000.0%0.21%
5.0%
ARYA ARYA SCIENCES ACQUISIT...Reduce  $13,386
23.4%
971,430
-2.9%
0.20%
32.9%
BLSA BCLS ACQUISITION CORP  $13,213
-5.1%
1,250,0000.0%0.20%
2.1%
MIST MILESTONE PHARMACEUTIC...Reduce  $13,007
-16.6%
2,246,503
-3.5%
0.20%
-10.1%
EYPT EYEPOINT PHARMACEUTICA...New  $12,7001,250,0000.19%
RPTX REPARE THERAPEUTICS INC  $12,552
-10.5%
409,0000.0%0.19%
-3.6%
OCUL OCULAR THERAPEUTIX INC  $12,308
-20.7%
750,0000.0%0.19%
-14.3%
TXMD THERAPEUTICSMD INC  $10,469
10.7%
7,812,5000.0%0.16%
19.7%
ARYD ARYA SCIENCES ACQU COR...cl aNew  $10,4731,000,0000.16%
FLACU FRAZIER LIFESCIENCES A...unit 12/09/2025  $10,160
-2.1%
1,000,0000.0%0.15%
5.5%
FSII FS DEVELOPMENT CORP IINew  $9,9601,000,0000.15%
PHAS PHASEBIO PHARMACEUTICA...New  $9,8612,850,0000.15%
KALV KALVISTA PHARMACEUTICA...New  $8,992350,0000.14%
COGT COGENT BIOSCIENCES INC  $9,005
-21.8%
1,025,6410.0%0.14%
-15.5%
FVAM 5 01 ACQUISITION CORP  $7,463
-2.2%
750,0000.0%0.11%
5.6%
HLXA HELIX ACQUISITION CORP  $7,147
-10.2%
700,0000.0%0.11%
-2.7%
HSAQ HEALTH SCIENCES ACQ CO...  $6,994
-12.6%
625,0000.0%0.10%
-6.2%
SYRS SYROS PHARMACEUTICALS INCNew  $6,732900,0000.10%
VRDN VIRIDIAN THERAPEUTICS INCNew  $5,219312,3280.08%
XFOR X4 PHARMACEUTICALS INC  $4,623
33.9%
536,9620.0%0.07%
45.8%
IMRA IMARA INC  $2,100
-61.7%
248,8040.0%0.03%
-58.4%
CEREW CEREVEL THERAPEUTICS H...*w exp 06/09/2027  $1,006
-23.7%
233,3330.0%0.02%
-16.7%
OVID OVID THERAPEUTICS INCSold out  $0-285,000-0.01%
PROF PROFOUND MEDICAL CORPSold out  $0-192,311-0.06%
MGEN MIRAGEN THERAPEUTICS INCSold out  $0-451,932-0.10%
CRNX CRINETICS PHARMACEUTIC...Sold out  $0-564,102-0.11%
PASG PASSAGE BIO INCSold out  $0-322,630-0.12%
LYRA LYRA THERAPEUTICS INCSold out  $0-815,849-0.13%
ADAP ADAPTIMMUNE THERAPEUTI...sponds adrSold out  $0-2,499,025-0.19%
VXRT VAXART INCSold out  $0-2,742,271-0.22%
MARINUS PHARMACEUTICAL...Sold out  $0-1,300,000-0.22%
ALEC ALECTOR INCSold out  $0-1,616,879-0.34%
PAND PANDION THERAPEUTICS INCSold out  $0-1,770,023-0.37%
ARQT ARCUTIS BIOTHERAPEUTIC...Sold out  $0-1,165,184-0.46%
PACB PACIFIC BIOSCIENCES OF...Sold out  $0-1,987,997-0.72%
CRDF CARDIFF ONCOLOGY INCSold out  $0-3,290,000-0.83%
LEGN LEGEND BIOTECH CORPsponsored adsSold out  $0-2,408,292-0.95%
INBX INHIBRX INCSold out  $0-2,129,003-0.98%
FPRX FIVE PRIME THERAPEUTIC...Sold out  $0-4,285,161-1.02%
KROS KEROS THERAPEUTICS INCSold out  $0-1,875,000-1.85%
ARVN ARVINAS INCSold out  $0-3,672,872-4.36%