RA Capital Management Q3 2023 significant ownership

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RA Capital Management is required to file a 13D/G report to the SEC when the ownership of a company's total stock issue exceeds 5%.

13F

13D/G

RA Capital Management Q3 2023 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
	Filed	Shares	Percentage
CymaBay Therapeutics, Inc.	September 22, 2023	6,940,000	6.2%
BELLUS Health Inc.^{Sold out}	August 14, 2023	0	0.0%
Kinnate Biopharma Inc.^{Sold out}	August 14, 2023	0	0.0%
Vor Biopharma Inc.	August 11, 2023	22,780,343	33.7%
DICE Therapeutics, Inc.^{Sold out}	August 09, 2023	0	0.0%
Acumen Pharmaceuticals, Inc.	July 25, 2023	14,981,618	25.9%
Talaris Therapeutics, Inc.	July 06, 2023	2,333,175	5.5%
Aerovate Therapeutics, Inc.	June 27, 2023	8,293,148	30.0%
Satsuma Pharmaceuticals, Inc.^{Sold out}	June 12, 2023	0	0.0%
ARYA Sciences Acquisition Corp V^{Sold out}	May 15, 2023	0	0.0%
DA32 Life Science Tech Acquisition Corp.^{Sold out}	May 15, 2023	0	0.0%
Travere Therapeutics, Inc.^{Sold out}	May 15, 2023	0	0.0%
Orchard Therapeutics plc	March 20, 2023	18,564,300	10.0%
Enliven Therapeutics, Inc.	February 27, 2023	2,122,465	5.2%
5:01 Acquisition Corp.^{Sold out}	February 14, 2023	0	0.0%
BCLS Acquisition Corp.^{Sold out}	February 14, 2023	0	0.0%
CONCERT PHARMACEUTICALS, INC.	February 14, 2023	5,199,746	10.0%
Entera Bio Ltd.	February 14, 2023	295,966	1.0%
Instil Bio, Inc.^{Sold out}	February 14, 2023	0	0.0%
IO Biotech, Inc.	February 14, 2023	1,127,260	3.9%
Magenta Therapeutics, Inc.^{Sold out}	February 14, 2023	0	0.0%
Milestone Pharmaceuticals Inc.^{Sold out}	February 14, 2023	0	0.0%
Orchestra BioMed Holdings, Inc.	February 14, 2023	610,283	5.4%
PARDES BIOSCIENCES, INC.^{Sold out}	February 14, 2023	0	0.0%
PhaseBio Pharmaceuticals Inc^{Sold out}	February 14, 2023	0	0.0%
Pyxis Oncology, Inc.^{Sold out}	February 14, 2023	0	0.0%
RELMADA THERAPEUTICS, INC.^{Sold out}	February 14, 2023	0	0.0%
SYNLOGIC, INC.^{Sold out}	February 14, 2023	0	0.0%
Vera Therapeutics, Inc.^{Sold out}	February 14, 2023	0	0.0%
Achilles Therapeutics plc	December 30, 2022	1,607,834	3.9%
LianBio^{Sold out}	November 14, 2022	0	0.0%
Olema Pharmaceuticals, Inc.^{Sold out}	November 14, 2022	0	0.0%
OTONOMY, INC.^{Sold out}	November 14, 2022	0	0.0%
STANDARD BIOTOOLS INC.^{Sold out}	November 14, 2022	0	0.0%
VERU INC.^{Sold out}	November 14, 2022	0	0.0%
Xilio Therapeutics, Inc.^{Sold out}	November 14, 2022	0	0.0%
Forma Therapeutics Holdings, Inc.^{Sold out}	October 14, 2022	0	0.0%
POINT Biopharma Global Inc.^{Sold out}	September 26, 2022	0	0.0%
Third Harmonic Bio, Inc.	September 26, 2022	3,475,687	8.6%
Akouos, Inc.^{Sold out}	August 15, 2022	0	0.0%
Cyteir Therapeutics, Inc.^{Sold out}	August 15, 2022	0	0.0%
KalVista Pharmaceuticals, Inc.^{Sold out}	August 15, 2022	0	0.0%
scPharmaceuticals Inc.^{Sold out}	August 15, 2022	0	0.0%
TScan Therapeutics, Inc.^{Sold out}	August 15, 2022	0	0.0%
Wave Life Sciences Ltd.	June 21, 2022	17,269,811	20.0%
Kala Pharmaceuticals, Inc.	June 03, 2022	3,412,868	4.7%
Bolt Biotherapeutics, Inc.^{Sold out}	May 16, 2022	0	0.0%
Phathom Pharmaceuticals, Inc.^{Sold out}	May 16, 2022	0	0.0%
ZOGENIX, INC.^{Sold out}	May 16, 2022	0	0.0%
Atea Pharmaceuticals, Inc.^{Sold out}	February 14, 2022	0	0.0%
ChemoCentryx, Inc.^{Sold out}	February 14, 2022	0	0.0%
CytomX Therapeutics, Inc.^{Sold out}	February 14, 2022	0	0.0%
Frazier Lifesciences Acquisition Corp^{Sold out}	February 14, 2022	0	0.0%
Nautilus Biotechnology, Inc.	February 14, 2022	2,436,430	2.0%
NOVAVAX INC	February 14, 2022	2,097,794	2.8%
Seres Therapeutics, Inc.^{Sold out}	February 14, 2022	0	0.0%
Tango Therapeutics, Inc.	February 14, 2022	2,250,000	2.6%
Viridian Therapeutics, Inc.\DE^{Sold out}	February 14, 2022	0	0.0%
X4 Pharmaceuticals, Inc	February 14, 2022	1,136,000	3.9%
Aadi Bioscience, Inc.^{Sold out}	November 15, 2021	0	0.0%
ARDELYX, INC.^{Sold out}	November 15, 2021	0	0.0%
ARYA Sciences Acquisition Corp IV^{Sold out}	November 15, 2021	0	0.0%
CURIS INC^{Sold out}	November 15, 2021	0	0.0%
Helix Acquisition Corp^{Sold out}	November 15, 2021	0	0.0%
Inozyme Pharma, Inc.^{Sold out}	November 15, 2021	0	0.0%
Trillium Therapeutics Inc.^{Sold out}	November 15, 2021	0	0.0%
Adverum Biotechnologies, Inc.^{Sold out}	August 16, 2021	0	0.0%
Therapeutics Acquisition Corp.	June 30, 2021	1,098,318	7.8%
Novan, Inc.^{Sold out}	June 21, 2021	0	0.0%
CATABASIS PHARMACEUTICALS INC	June 15, 2021	5,745,744	7.5%
FIVE PRIME THERAPEUTICS, INC.^{Sold out}	May 17, 2021	0	0.0%
Lyra Therapeutics, Inc.^{Sold out}	May 17, 2021	0	0.0%
Pandion Therapeutics, Inc.^{Sold out}	May 17, 2021	0	0.0%
ARYA Sciences Acquisition Corp III	February 16, 2021	1,000,000	6.7%
BCTG Acquisition Corp.	February 16, 2021	1,250,000	5.8%
Crinetics Pharmaceuticals, Inc.	February 16, 2021	564,102	1.7%
Prevail Therapeutics Inc.^{Sold out}	February 16, 2021	0	0.0%
Verastem, Inc.^{Sold out}	February 16, 2021	0	0.0%
Iterum Therapeutics plc^{Sold out}	February 11, 2021	0	0.0%
ARVINAS, INC.^{Sold out}	February 10, 2021	0	0.0%
Cardiff Oncology, Inc.^{Sold out}	February 10, 2021	0	0.0%
Keros Therapeutics, Inc.^{Sold out}	February 10, 2021	0	0.0%
TG THERAPEUTICS, INC.	February 10, 2021	8,685,471	6.4%
MIRAGEN THERAPEUTICS, INC.	December 17, 2020	451,932	11.6%
Eidos Therapeutics, Inc.	October 07, 2020	1,798,339	4.7%
iTeos Therapeutics, Inc.	August 05, 2020	4,417,259	13.2%
BIOCRYST PHARMACEUTICALS INC^{Sold out}	February 14, 2020	0	0.0%
Eiger BioPharmaceuticals, Inc.^{Sold out}	February 14, 2020	0	0.0%
Myovant Sciences Ltd.^{Sold out}	February 14, 2020	0	0.0%
Retrophin, Inc.	February 14, 2020	4,252,453	9.9%
Black Diamond Therapeutics, Inc.	February 05, 2020	2,589,904	7.2%
Ra Pharmaceuticals, Inc.	October 11, 2019	3,971,750	8.4%
InflaRx N.V.^{Sold out}	July 10, 2019	0	0.0%
Biohaven Pharmaceutical Holding Co Ltd.^{Sold out}	February 14, 2019	0	0.0%
Kadmon Holdings, Inc.	February 14, 2019	2,666,666	2.3%
Krystal Biotech, Inc.^{Sold out}	February 14, 2019	0	0.0%
Spero Therapeutics, Inc.^{Sold out}	February 14, 2019	0	0.0%
Synthorx, Inc.	December 17, 2018	9,724,598	30.4%
Dicerna Pharmaceuticals Inc	November 07, 2018	2,814,589	4.5%
SUNESIS PHARMACEUTICALS INC	July 10, 2018	500,000	1.4%
ACHILLION PHARMACEUTICALS INC	February 14, 2018	585,890	0.4%
AQUINOX PHARMACEUTICALS, INC^{Sold out}	February 14, 2018	0	0.0%
ARCA biopharma, Inc.	February 14, 2018	324,490	2.7%
AveXis, Inc.	February 14, 2018	1,171,278	3.7%
ENDOCYTE INC	February 14, 2018	3,364,648	7.0%
PROTEON THERAPEUTICS INC	February 14, 2018	1,679,205	9.4%
Strongbridge Biopharma plc^{Sold out}	February 14, 2018	0	0.0%
TENAX THERAPEUTICS, INC.^{Sold out}	February 14, 2018	0	0.0%
Axovant Sciences Ltd.^{Sold out}	February 14, 2017	0	0.0%
Cidara Therapeutics, Inc.^{Sold out}	February 14, 2017	0	0.0%
DERMA SCIENCES, INC.^{Sold out}	February 14, 2017	0	0.0%
Protagonist Therapeutics, Inc	February 14, 2017	692,563	4.1%
SANUWAVE Health, Inc.^{Sold out}	February 14, 2017	0	0.0%
Zynerba Pharmaceuticals, Inc.^{Sold out}	February 14, 2017	0	0.0%
ALCOBRA LTD.	October 21, 2016	1,308,234	4.7%
Vitae Pharmaceuticals, Inc	August 15, 2016	2,119,036	7.3%
ACADIA PHARMACEUTICALS INC^{Sold out}	February 16, 2016	0	0.0%
AGILE THERAPEUTICS INC^{Sold out}	February 16, 2016	0	0.0%
AmpliPhi Biosciences Corp	February 16, 2016	365,393	4.9%
Arbutus Biopharma Corp^{Sold out}	February 16, 2016	0	0.0%
Aurinia Pharmaceuticals Inc.	February 16, 2016	618,519	1.9%
Blueprint Medicines Corp	February 16, 2016	878,348	3.2%
COLLEGIUM PHARMACEUTICAL, INC	February 16, 2016	857,683	3.7%
DYNAVAX TECHNOLOGIES CORP^{Sold out}	February 16, 2016	0	0.0%
SCYNEXIS INC^{Sold out}	February 16, 2016	0	0.0%
TREVENA INC^{Sold out}	February 16, 2016	0	0.0%
VICAL INC^{Sold out}	February 16, 2016	0	0.0%
WaferGen Bio-systems, Inc.	February 16, 2016	560,000	3.9%
Xencor Inc^{Sold out}	February 16, 2016	0	0.0%
SANGAMO BIOSCIENCES INC	September 29, 2015	1,220,209	1.7%
ARCA biopharma, Inc.	June 25, 2015	5,678,592	9.0%
AmpliPhi Biosciences Corp	February 17, 2015	26,785,712	9.7%
ARROWHEAD RESEARCH CORP^{Sold out}	February 17, 2015	0	0.0%
DYAX CORP	February 17, 2015	4,945,697	3.6%
ENANTA PHARMACEUTICALS INC^{Sold out}	February 17, 2015	0	0.0%
ENZO BIOCHEM INC^{Sold out}	February 17, 2015	0	0.0%
Furiex Pharmaceuticals, Inc.^{Sold out}	February 17, 2015	0	0.0%
Mirati Therapeutics, Inc.	February 17, 2015	165,516	1.2%
NOVAVAX INC	February 17, 2015	3,241,083	1.4%
Ocera Therapeutics, Inc.	February 17, 2015	523,035	2.6%
Prothena Corp plc^{Sold out}	February 17, 2015	0	0.0%
pSivida Corp.^{Sold out}	February 17, 2015	0	0.0%
REPROS THERAPEUTICS INC.^{Sold out}	February 17, 2015	0	0.0%
SUNESIS PHARMACEUTICALS INC^{Sold out}	February 17, 2015	0	0.0%
TENGION INC	February 17, 2015	3,984,267	9.9%
TherapeuticsMD, Inc.	February 17, 2015	3,211,132	2.1%
Versartis, Inc.	February 17, 2015	231,267	1.0%
TEKMIRA PHARMACEUTICALS Corp	January 20, 2015	2,214,800	9.9%
CORONADO BIOSCIENCES INC^{Sold out}	February 14, 2014	0	0.0%
DYNAVAX TECHNOLOGIES CORP	February 14, 2014	25,999,886	9.9%
HYPERION THERAPEUTICS INC^{Sold out}	February 14, 2014	0	0.0%
INSMED INC^{Sold out}	February 14, 2014	0	0.0%
KERYX BIOPHARMACEUTICALS INC^{Sold out}	February 14, 2014	0	0.0%
MEI Pharma, Inc.	February 14, 2014	816,666	3.8%
MELA SCIENCES, INC. /NY^{Sold out}	February 14, 2014	0	0.0%
NEWLINK GENETICS CORP^{Sold out}	February 14, 2014	0	0.0%
OMEROS CORP^{Sold out}	February 14, 2014	0	0.0%
ONCOGENEX PHARMACEUTICALS, INC.^{Sold out}	February 14, 2014	0	0.0%
SENOMYX INC^{Sold out}	February 14, 2014	0	0.0%
XOMA Corp	February 14, 2014	687,879	0.7%
TRANZYME INC	May 08, 2013	2,700,000	9.8%
Anacor Pharmaceuticals Inc^{Sold out}	February 14, 2013	0	0.0%
Anthera Pharmaceuticals Inc^{Sold out}	February 14, 2013	0	0.0%
GENTA INC DE/	February 14, 2013	662,117,262	9.9%
POZEN INC /NC^{Sold out}	February 14, 2013	0	0.0%
UROPLASTY INC^{Sold out}	February 14, 2013	0	0.0%
Vanda Pharmaceuticals Inc.^{Sold out}	February 14, 2013	0	0.0%
VENTRUS BIOSCIENCES INC	February 14, 2013	628,092	3.4%
SYNAGEVA BIOPHARMA CORP	February 17, 2012	181,499	0.9%
ADVENTRX PHARMACEUTICALS INC^{Sold out}	February 14, 2012	0	0.0%
Alexza Pharmaceuticals Inc.	February 14, 2012	1,622,967	2.2%
CardioNet, Inc.^{Sold out}	February 14, 2012	0	0.0%
SEQUENOM INC	February 14, 2012	4,681,026	4.1%
SYNAGEVA BIOPHARMA CORP^{Sold out}	February 14, 2012	0	0.0%
TearLab Corp	February 14, 2012	1,020,545	5.0%
TENGION INC	February 14, 2012	1,060,070	4.4%
AASTROM BIOSCIENCES INC	February 14, 2011	178,125	0.5%
BIOSPECIFICS TECHNOLOGIES CORP	February 14, 2011	300,000	4.8%
DEPOMED INC^{Sold out}	February 14, 2011	0	0.0%
TELIK INC^{Sold out}	February 14, 2011	0	0.0%
CYPRESS BIOSCIENCE INC	September 30, 2010	1,000,000	2.6%
Ardea Biosciences, Inc./DE^{Sold out}	February 16, 2010	0	0.0%
Northstar Neuroscience, Inc.^{Sold out}	April 20, 2009	0	0.0%
ADOLOR CORP^{Sold out}	February 17, 2009	0	0.0%
AP PHARMA INC /DE/^{Sold out}	February 17, 2009	0	0.0%
ARADIGM CORP^{Sold out}	February 17, 2009	0	0.0%
ARCA biopharma, Inc.^{Sold out}	February 17, 2009	0	0.0%
ARQULE INC^{Sold out}	February 17, 2009	0	0.0%
ATHERSYS, INC / NEW	February 17, 2009	300,000	1.5%
CURIS INC	February 17, 2009	2,632,198	4.0%
CytRx Oncology Corp^{Sold out}	February 17, 2009	0	0.0%
GENELABS TECHNOLOGIES INC /CA^{Sold out}	February 17, 2009	0	0.0%
JAVELIN PHARMACEUTICALS, INC^{Sold out}	February 17, 2009	0	0.0%
MiddleBrook Pharmaceuticals, Inc.^{Sold out}	February 17, 2009	0	0.0%
NEUROCRINE BIOSCIENCES INC^{Sold out}	February 17, 2009	0	0.0%
Pharmasset Inc	February 17, 2009	703,712	2.5%
Chelsea Therapeutics International, Ltd.	February 14, 2008	876,172	2.9%
COUGAR BIOTECHNOLOGY INC	February 14, 2008	159,873	0.9%
GENAERA CORP^{Sold out}	February 14, 2008	0	0.0%
IOMAI CORP	February 14, 2008	351,406	1.2%
NEXMED INC^{Sold out}	February 14, 2008	0	0.0%
RENOVIS INC^{Sold out}	February 14, 2008	0	0.0%
VASOGEN INC	February 14, 2008	425,531	1.9%
ROCKWELL MEDICAL TECHNOLOGIES INC	December 10, 2007	1,366,667	9.9%
AP PHARMA INC /DE/	June 20, 2007	2,424,242	8.8%
LIPID SCIENCES INC/	March 28, 2007	3,713,962	10.0%
AVIGEN INC \DE	February 14, 2007	1,000	0.0%
Chelsea Therapeutics International, Ltd.	February 14, 2007	1,357,802	6.9%
GENAERA CORP	February 14, 2007	6,328,163	6.0%
VASOGEN INC	November 20, 2006	10,638,298	7.0%
PRAECIS PHARMACEUTICALS INC^{Sold out}	February 08, 2006	0	0.0%

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