| CM Management, LLC | 1,500,000 | $1,620,000 | 1.72% |
|---|
| Soleus Capital Management, L.P. | 14,803,015 | $15,987,256 | 1.48% |
|---|
| ARMISTICE CAPITAL, LLC | 17,136,000 | $18,506,880 | 0.28% |
|---|
| SPHERA FUNDS MANAGEMENT LTD. | 1,228,126 | $1,326,376 | 0.24% |
|---|
| GSA CAPITAL PARTNERS LLP | 971,441 | $1,049 | 0.09% |
|---|
| NJ State Employees Deferred Compensation Plan | 200,000 | $216,000 | 0.03% |
|---|
| Providence Wealth Advisors, LLC | 27,500 | $29,013 | 0.03% |
|---|
| UBS OCONNOR LLC | 1,151,765 | $1,243,906 | 0.03% |
|---|
| XTX Topco Ltd | 164,238 | $177,377 | 0.03% |
|---|
| JACOBS LEVY EQUITY MANAGEMENT, INC | 3,369,076 | $3,638,602 | 0.02% |
|---|
| ACADIAN ASSET MANAGEMENT LLC | 4,660,740 | $5,033 | 0.02% |
|---|
| State of Wyoming | 86,187 | $93,082 | 0.02% |
|---|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 594,200 | $641,736 | 0.02% |
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| Assenagon Asset Management S.A. | 2,769,841 | $2,991,428 | 0.01% |
|---|
| Connecticut Wealth Management, LLC | 115,200 | $124,416 | 0.01% |
|---|
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 94,257 | $1,444 | 0.00% |
|---|
| Fort Point Capital Partners LLC | 17,000 | $18,360 | 0.00% |
|---|
| Connor, Clark & Lunn Investment Management Ltd. | 591,629 | $638,959 | 0.00% |
|---|
| Weiss Multi-Strategy Advisers LLC | 119,151 | $129 | 0.00% |
|---|
| VOYA INVESTMENT MANAGEMENT LLC | 2,057,096 | $2,221,664 | 0.00% |
|---|