$449 Million is the total value of INTERNATIONAL BIOTECHNOLOGY TRUST PLC's 73 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 30.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| AMGN | Buy | Amgen Inc | $32,565,000 | +29.5% | 144,746 | +22.4% | 7.26% | +19.6% |
| NBIX | Sell | Neurocrine Biosciences Inc | $23,848,000 | -14.0% | 280,000 | -3.3% | 5.31% | -20.6% |
| ALNY | Buy | Alnylam Pharmaceuticals Inc | $21,706,000 | +53.3% | 128,000 | +70.7% | 4.84% | +41.6% |
| INCY | Buy | Incyte Corp | $20,930,000 | +12.6% | 285,000 | +5.4% | 4.66% | +4.0% |
| GILD | Sell | Gilead Sciences Inc | $20,533,000 | -27.0% | 282,784 | -29.8% | 4.58% | -32.6% |
| BHVN | Sell | BIOHAVEN PHARMACTL HLDG CO L | $19,282,000 | -21.3% | 139,900 | -20.7% | 4.30% | -27.3% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $18,549,000 | +6.5% | 126,500 | +28.4% | 4.13% | -1.6% |
| PTCT | PTC Therapuetics COM | $17,884,000 | +7.0% | 449,000 | 0.0% | 3.98% | -1.2% | |
| SGEN | Buy | SEAGEN INC | $17,478,000 | -6.1% | 113,200 | +3.2% | 3.89% | -13.3% |
| VRTX | Vertex Pharmaceuticals Inc | $16,958,000 | +21.1% | 77,222 | 0.0% | 3.78% | +11.8% | |
| ILMN | Buy | ILLUMINA INC | $14,266,000 | +30.4% | 37,500 | +38.9% | 3.18% | +20.4% |
| TVTX | TRAVERE THERAPEUTICS INC | $11,803,000 | +28.1% | 380,000 | 0.0% | 2.63% | +18.3% | |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $11,613,000 | +25.1% | 138,100 | +33.9% | 2.59% | +15.5% |
| BIIB | Buy | Biogen Inc | $11,398,000 | +58.0% | 47,500 | +86.3% | 2.54% | +46.0% |
| IONS | Buy | Ionis Pharmaceuticals Inc | $10,805,000 | +619.4% | 355,088 | +692.9% | 2.41% | +564.9% |
| HZNP | Sell | HORIZON THERAPEUTICS PUB LTD | $10,762,000 | -58.7% | 99,873 | -58.0% | 2.40% | -61.8% |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | $10,063,000 | +11.6% | 236,000 | 0.0% | 2.24% | +3.0% | |
| EXC | New | Exelixis Inc | $9,985,000 | – | 546,534 | +100.0% | 2.22% | – |
| BMRN | Buy | Biomarin Pharmaceutical Inc | $9,291,000 | +117.9% | 105,156 | +90.7% | 2.07% | +101.4% |
| SUPN | SUPERNUS PHARMACEUTICALS INC | $8,675,000 | +9.3% | 297,500 | 0.0% | 1.93% | +1.0% | |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $8,192,000 | – | 108,200 | +100.0% | 1.82% | – |
| AUPH | Buy | AURINIA PHARMACEUTICALS INC | $7,647,000 | +180.7% | 334,500 | +170.9% | 1.70% | +159.4% |
| REGN | Buy | Regeneron Pharmaceuticals | $7,641,000 | +64.1% | 12,100 | +57.1% | 1.70% | +51.6% |
| GH | Buy | GUARDANT HEALTH INC | $7,451,000 | +63.3% | 74,500 | +104.1% | 1.66% | +50.8% |
| ITCI | Buy | INTRA CELLULAR THERAPIES INC | $5,924,000 | +100.3% | 113,456 | +42.8% | 1.32% | +85.1% |
| DYN | Buy | DYNE THERAPEUTICS INC | $5,641,000 | +38.9% | 476,000 | +90.4% | 1.26% | +28.4% |
| JAZZ | JAZZ PHARMACEUTICALS PLC | $5,632,000 | -2.1% | 44,200 | 0.0% | 1.26% | -9.6% | |
| BGNE | New | BEIGENE LTDsponsored adr | $5,402,000 | – | 20,000 | +100.0% | 1.20% | – |
| KALV | Kalvista Pharmaceuticals Inc | $5,066,000 | -24.2% | 383,233 | 0.0% | 1.13% | -30.0% | |
| KDNY | Buy | CHINOOK THERAPEUTICS INC | $4,714,000 | +57.6% | 289,389 | +23.1% | 1.05% | +45.4% |
| ASND | Ascendis Pharma ASsponsored adr | $3,955,000 | -15.6% | 29,400 | 0.0% | 0.88% | -22.0% | |
| INSM | Sell | INSMED INC | $3,299,000 | -50.3% | 121,100 | -49.8% | 0.74% | -54.1% |
| QURE | Sell | UNIQURE NV | $3,225,000 | -44.7% | 155,500 | -14.7% | 0.72% | -49.0% |
| VERA | New | VERA THERAPEUTICS INCcl a | $3,198,000 | – | 120,535 | +100.0% | 0.71% | – |
| KRYS | New | KRYSTAL BIOTECH INC | $3,148,000 | – | 45,000 | +100.0% | 0.70% | – |
| TPTX | Sell | TURNING POINT THERAPEUTICS I | $2,945,000 | -68.0% | 61,741 | -55.5% | 0.66% | -70.5% |
| NTLA | New | INTELLIA THERAPEUTICS INC | $2,836,000 | – | 24,000 | +100.0% | 0.63% | – |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS IN | $2,771,000 | +399.3% | 94,800 | +334.9% | 0.62% | +360.4% |
| IDYA | IDEAYA BIOSCIENCES INC | $2,577,000 | -7.2% | 109,000 | 0.0% | 0.57% | -14.3% | |
| ZLAB | ZAI LAB LTDadr | $2,447,000 | -40.3% | 38,958 | 0.0% | 0.54% | -44.8% | |
| HCM | HUTCHMED CHINA LTDsponsored ads | $2,377,000 | -4.3% | 68,000 | 0.0% | 0.53% | -11.5% | |
| ORIC | Buy | ORIC PHARMACEUTICALS INC | $2,249,000 | +103.7% | 153,000 | +188.7% | 0.50% | +88.3% |
| ZGNX | ZOGENIX INC | $2,194,000 | +7.0% | 135,000 | 0.0% | 0.49% | -1.2% | |
| BPMC | Blueprint Medicines Corp | $2,089,000 | +4.3% | 19,500 | 0.0% | 0.46% | -3.7% | |
| STRO | SUTRO BIOPHARMA INC | $2,073,000 | -21.1% | 139,331 | 0.0% | 0.46% | -27.1% | |
| ARNA | Arena Pharmaceuticals Inc | $1,951,000 | +56.1% | 21,000 | 0.0% | 0.44% | +44.5% | |
| FATE | FATE THERAPEUTICS INC | $1,638,000 | -1.3% | 28,000 | 0.0% | 0.36% | -8.8% | |
| HARP | HARPOON THERAPEUTICS INC | $1,623,000 | -4.3% | 215,000 | 0.0% | 0.36% | -11.5% | |
| SWTX | SPRINGWORKS THERAPEUTICS INC | $1,550,000 | -2.0% | 25,000 | 0.0% | 0.34% | -9.7% | |
| APLS | New | APELLIS PHARMACEUTICALS INC | $1,536,000 | – | 32,500 | +100.0% | 0.34% | – |
| KOD | KODIAK SCIENCES INC | $1,373,000 | -11.6% | 16,200 | 0.0% | 0.31% | -18.4% | |
| RCKT | ROCKET PHARMACEUTICALS INC | $1,375,000 | -27.0% | 63,000 | 0.0% | 0.31% | -32.6% | |
| CCXI | Sell | CHEMOCENTRYX INC | $1,314,000 | -81.6% | 36,100 | -61.7% | 0.29% | -83.0% |
| DNLI | New | DENALI THERAPEUTICS INC | $1,158,000 | – | 26,000 | +100.0% | 0.26% | – |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | $1,106,000 | -22.7% | 58,000 | 0.0% | 0.25% | -28.7% | |
| FOLD | Amicus Therapeutics Inc | $1,094,000 | +21.0% | 94,600 | 0.0% | 0.24% | +11.9% | |
| FULC | New | FULCRUM THERAPEUTICS INC | $1,080,000 | – | 61,000 | +100.0% | 0.24% | – |
| NKTR | NEKTAR THERAPEUTICS | $905,000 | -24.6% | 67,000 | 0.0% | 0.20% | -30.3% | |
| BBIO | New | BRIDGEBIO PHARMA INC | $881,000 | – | 52,800 | +100.0% | 0.20% | – |
| IMAB | I MABsponsored ads | $851,000 | -34.6% | 18,000 | 0.0% | 0.19% | -39.5% | |
| EXAS | Exact Sciences Corp | $833,000 | -18.4% | 10,700 | 0.0% | 0.19% | -24.4% | |
| XENE | XENON PHARMACEUTICALS INC | $797,000 | +105.4% | 25,500 | 0.0% | 0.18% | +89.4% | |
| ALLO | New | ALLOGENE THERAPEUTICS INC | $747,000 | – | 50,000 | +100.0% | 0.17% | – |
| PRTA | New | PROTHENA CORP PLC | $741,000 | – | 15,000 | +100.0% | 0.16% | – |
| AGIO | Agios Pharmaceuticals Inc | $707,000 | -28.7% | 21,500 | 0.0% | 0.16% | -33.9% | |
| NKTX | Sell | NKARTA INC | $617,000 | -60.7% | 40,200 | -28.8% | 0.14% | -63.9% |
| IMVT | IMMUNOVANT INC | $511,000 | -1.9% | 60,000 | 0.0% | 0.11% | -9.5% | |
| ANAB | ANAPTYSBIO INC | $348,000 | +28.4% | 10,000 | 0.0% | 0.08% | +20.0% | |
| GMDA | GAMIDA CELL LTD | $271,000 | -35.2% | 107,000 | 0.0% | 0.06% | -40.6% | |
| BDTX | BLACK DIAMOND THERAPEUTICS I | $235,000 | -36.7% | 44,000 | 0.0% | 0.05% | -41.6% | |
| RLMD | RELMADA THERAPEUTICS INC | $225,000 | -13.8% | 10,000 | 0.0% | 0.05% | -20.6% | |
| LEGN | Sell | LEGEND BIOTECH CORPsponsored ads | $209,000 | -91.6% | 4,500 | -90.9% | 0.05% | -92.2% |
| New | 2SEVENTY BIO INC | $94,000 | – | 3,666 | +100.0% | 0.02% | – | |
| ESPR | Exit | ESPERION THERAPEUTICS INC NE | $0 | – | -9,500 | -100.0% | -0.03% | – |
| FGEN | Exit | FibroGen Inc | $0 | – | -19,700 | -100.0% | -0.05% | – |
| BLUE | Exit | Bluebird Bio Inc | $0 | – | -11,000 | -100.0% | -0.05% | – |
| AXSM | Exit | AXSOME THERAPEUTICS INC | $0 | – | -14,000 | -100.0% | -0.11% | – |
| DCPH | Exit | DECIPHERA PHARMACEUTICALS INC | $0 | – | -16,600 | -100.0% | -0.14% | – |
| ALLK | Exit | ALLAKOS INC | $0 | – | -15,700 | -100.0% | -0.40% | – |
| ENTA | Exit | ENANTA PHARMACEUTICALS INC | $0 | – | -40,000 | -100.0% | -0.55% | – |
| EXEL | Exit | Exelixis Inc | $0 | – | -489,534 | -100.0% | -2.50% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-02-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| GILEAD SCIENCES INC COMMO | 28 | Q3 2023 | 9.3% |
| INCYTE CORP INC COM | 28 | Q3 2023 | 7.9% |
| BIOMARIN PHARMACEUTICALS INC | 28 | Q3 2023 | 7.5% |
| REGENERON PHARMS. | 27 | Q3 2023 | 9.0% |
| BIOGEN INC COMMON STOCK | 26 | Q3 2023 | 8.7% |
| VERTEX PHARMS. | 25 | Q3 2023 | 8.4% |
| AMGEN INC COM | 25 | Q3 2023 | 7.9% |
| NEUROCRINE BIOSCIENCES INC | 25 | Q3 2023 | 6.9% |
| ALYNYLAM PHARMACEUTICALS INC | 25 | Q3 2023 | 6.7% |
| IONIS PHARMS. | 25 | Q3 2023 | 4.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Altus Pharmaceuticals Inc. | February 12, 2009 | ? | ? |
| MICROMET, INC. | February 14, 2008 | 1,907,390 | 4.7% |
| EPIMMUNE INC | February 15, 2005 | 1,279,659 | 8.0% |
| ESSENTIAL THERAPEUTICS INC | April 29, 2003 | 2,500,000 | 11.7% |
| TARGETED GENETICS CORP /WA/ | April 18, 2003 | ? | ? |
| ESSENTIAL THERAPEUTICS INC | November 05, 2001 | 11 | 13.0% |
| ONYX PHARMACEUTICALS INC | October 15, 2001 | 11 | 13.0% |
| CORVAS INTERNATIONAL INC | October 12, 2001 | 11 | 13.0% |
| RIBOZYME PHARMACEUTICALS INC | October 05, 2001 | 11 | 13.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-08 |
| 13F-HR | 2023-05-18 |
| 13F-HR | 2023-02-01 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-16 |
| 13F-HR | 2022-05-20 |
| 13F-HR | 2022-02-15 |
| 13F-HR | 2021-11-12 |
| 13F-HR | 2021-08-11 |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.