Avidity Partners Management LP

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$4.51 Billion is the total value of Avidity Partners Management LP's 105 reported holdings in Q3 2021. The portfolio turnover from Q2 2021 to Q3 2021 was 49.1% .

All

			Value		Shares		↓ Weighting
XBI	New	SPDR SER TRcall	$379,770,000	–	3,021,000	+100.0%	8.41%	–
XLRN	New	ACCELERON PHARMA INCcall	$211,356,000	–	1,228,100	+100.0%	4.68%	–
MRTX	Buy	MIRATI THERAPEUTICS INC	$187,949,000	+54.5%	1,062,400	+41.1%	4.16%	+26.7%
ARVN	Buy	ARVINAS INC	$183,648,000	+28.6%	2,234,700	+20.5%	4.07%	+5.5%
ABBV	Buy	ABBVIE INC	$174,016,000	+4.1%	1,613,200	+8.7%	3.86%	-14.7%
VRTX	Sell	VERTEX PHARMACEUTICALS INC	$168,040,000	-12.3%	926,400	-2.5%	3.72%	-28.1%
ZNTL	Buy	ZENTALIS PHARMACEUTICALS INC	$166,187,000	+44.6%	2,493,800	+15.5%	3.68%	+18.5%
AVTR	Buy	AVANTOR INC	$132,831,000	+17.6%	3,247,700	+2.1%	2.94%	-3.6%
BHVN	Buy	BIOHAVEN PHARMACTL HLDG CO L	$129,770,000	+51.5%	934,200	+5.9%	2.88%	+24.1%
SNDX	Buy	SYNDAX PHARMACEUTICALS INC	$92,175,000	+16.3%	4,823,400	+4.5%	2.04%	-4.7%
REGN	New	REGENERON PHARMACEUTICALS	$92,169,000	–	152,300	+100.0%	2.04%	–
SGEN	Sell	SEAGEN INC	$91,183,000	-9.8%	537,000	-16.1%	2.02%	-26.0%
HZNP	Buy	HORIZON THERAPEUTICS PUB L	$90,480,000	+70.1%	826,000	+45.4%	2.00%	+39.4%
BPMC	Buy	BLUEPRINT MEDICINES CORP	$85,538,000	+72.7%	832,000	+47.7%	1.90%	+41.5%
AZN	New	ASTRAZENECA PLCsponsored adr	$84,805,000	–	1,412,000	+100.0%	1.88%	–
NBIX	Buy	NEUROCRINE BIOSCIENCES INC	$81,418,000	+22.8%	848,900	+24.7%	1.80%	+0.7%
ALNY	Buy	ALNYLAM PHARMACEUTICALS INC	$80,622,000	+143.9%	427,000	+119.0%	1.79%	+100.0%
LLY	Sell	LILLY ELI & CO	$76,247,000	-41.3%	330,000	-41.6%	1.69%	-51.9%
NUVB	Buy	NUVATION BIO INC	$72,199,000	+11.3%	7,263,488	+4.3%	1.60%	-8.7%
NTRA	Buy	NATERA INC	$71,177,000	+43.8%	638,700	+46.5%	1.58%	+17.9%
HOLX	Sell	HOLOGIC INC	$69,780,000	-13.5%	945,400	-21.8%	1.55%	-29.1%
BAX	New	BAXTER INTL INC	$69,331,000	–	862,000	+100.0%	1.54%	–
ARNA	Buy	ARENA PHARMACEUTICALS INC	$67,827,000	+5.5%	1,139,000	+20.8%	1.50%	-13.5%
ISEE	Buy	IVERIC BIO INC	$66,584,000	+653.7%	4,100,000	+192.9%	1.48%	+517.2%
UTHR	Buy	UNITED THERAPEUTICS CORP DEL	$64,788,000	+52.8%	351,000	+48.5%	1.44%	+25.2%
	New	STEVANATO GROUP S P A	$64,335,000	–	2,541,893	+100.0%	1.42%	–
SHC	Buy	SOTERA HEALTH CO	$62,185,000	+34.4%	2,378,000	+24.5%	1.38%	+10.2%
IDYA	Buy	IDEAYA BIOSCIENCES INC	$62,119,000	+43.0%	2,437,000	+17.7%	1.38%	+17.2%
	New	CARIBOU BIOSCIENCES INC	$59,056,000	–	2,474,067	+100.0%	1.31%	–
CTLT	Sell	CATALENT INC	$52,962,000	-9.3%	398,000	-26.3%	1.17%	-25.7%
GRTS	Buy	GRITSTONE BIO INC	$48,145,000	+148.5%	4,457,831	+110.1%	1.07%	+103.6%
LEGN	Buy	LEGEND BIOTECH CORPsponsored ads	$45,201,000	+76.2%	894,000	+43.0%	1.00%	+44.4%
OCDX	New	ORTHO CLINICAL DIAGNOSTICS H	$44,315,000	–	2,398,000	+100.0%	0.98%	–
PFE	New	PFIZER INC	$44,163,000	–	1,026,800	+100.0%	0.98%	–
ARWR	Buy	ARROWHEAD PHARMACEUTICALS IN	$42,059,000	+388.3%	673,700	+547.8%	0.93%	+300.0%
STTK	Buy	SHATTUCK LABS INC	$41,270,000	-26.6%	2,025,000	+4.4%	0.91%	-39.9%
RARE	New	ULTRAGENYX PHARMACEUTICAL IN	$41,036,000	–	455,000	+100.0%	0.91%	–
IMCR	Buy	IMMUNOCORE HLDGS PLCads	$40,614,000	+73.1%	1,095,600	+82.3%	0.90%	+42.0%
RNA	New	AVIDITY BIOSCIENCES INC	$40,516,000	–	1,645,000	+100.0%	0.90%	–
IOVA	New	IOVANCE BIOTHERAPEUTICS INC	$36,058,000	–	1,462,200	+100.0%	0.80%	–
INSM	Buy	INSMED INC	$35,582,000	+8.7%	1,292,000	+12.3%	0.79%	-11.0%
EXAS	Sell	EXACT SCIENCES CORP	$35,221,000	-52.0%	369,000	-37.5%	0.78%	-60.6%
CMPS	Buy	COMPASS PATHWAYS PLCsponsored ads	$34,709,000	-9.0%	1,162,000	+16.2%	0.77%	-25.4%
ATEC	Buy	ALPHATEC HLDGS INC	$33,961,000	-15.4%	2,786,000	+6.3%	0.75%	-30.7%
NTLA	Sell	INTELLIA THERAPEUTICS INC	$33,672,000	-45.3%	251,000	-33.9%	0.75%	-55.1%
IMAB	Sell	I MABsponsored ads	$32,910,000	-46.2%	454,000	-37.7%	0.73%	-55.9%
SPNE	Buy	SEASPINE HLDGS CORP	$30,563,000	-2.3%	1,943,000	+27.4%	0.68%	-19.9%
BLU	Buy	BELLUS HEALTH INC NEW	$30,344,000	+129.6%	4,942,000	+16.3%	0.67%	+88.2%
KYMR	New	KYMERA THERAPEUTICS INC	$30,222,000	–	514,500	+100.0%	0.67%	–
CYT	Sell	CYTEIR THERAPEUTICS INC	$29,544,000	-23.7%	1,683,441	-6.9%	0.66%	-37.4%
ALT	New	ALTIMMUNE INC	$24,519,000	–	2,167,900	+100.0%	0.54%	–
VIR	Buy	VIR BIOTECHNOLOGY INC	$22,413,000	+192.6%	515,000	+217.9%	0.50%	+140.1%
ALPN	Buy	ALPINE IMMUNE SCIENCES INC	$20,614,000	+53.2%	1,932,000	+29.2%	0.46%	+25.5%
EPIX	Sell	ESSA PHARMA INC	$19,600,000	-75.1%	2,450,000	-10.9%	0.43%	-79.6%
ACET	Buy	ADICET BIO INC	$18,970,000	-18.1%	2,419,600	+7.5%	0.42%	-32.9%
IPSC	Sell	CENTURY THERAPEUTICS INC	$18,600,000	-36.8%	739,269	-26.3%	0.41%	-48.2%
SIBN	Buy	SI-BONE INC	$17,804,000	-1.6%	831,200	+44.6%	0.39%	-19.4%
SANA	Sell	SANA BIOTECHNOLOGY INC	$17,445,000	+14.0%	774,644	-0.5%	0.39%	-6.5%
PATH	Buy	UIPATH INCcl a	$16,783,000	-17.6%	319,000	+6.3%	0.37%	-32.5%
	New	FIELD TRIP HEALTH LTD	$16,437,000	–	3,581,000	+100.0%	0.36%	–
LFST	Sell	LIFESTANCE HEALTH GROUP INC	$14,500,000	-52.7%	1,000,000	-9.1%	0.32%	-61.2%
PHAS	Buy	PHASEBIO PHARMACEUTICALS INC	$13,700,000	-14.7%	4,405,000	+2.1%	0.30%	-30.0%
	New	SEMA4 HOLDINGS CORP	$12,599,000	–	1,660,000	+100.0%	0.28%	–
GHRS		GH RESEARCH PLCordinary shares	$12,354,000	+1.5%	560,000	0.0%	0.27%	-16.7%
GRPH	Buy	GRAPHITE BIO INC	$12,276,000	-45.7%	748,995	+1.8%	0.27%	-55.5%
ACIU	Buy	AC IMMUNE SA	$11,673,000	-7.1%	1,739,600	+9.8%	0.26%	-23.8%
SCYX		SCYNEXIS INC	$10,918,000	-28.0%	2,060,000	0.0%	0.24%	-41.0%
HOWL	Sell	WEREWOLF THERAPEUTICS INC	$10,727,000	-5.4%	625,120	-3.9%	0.24%	-22.5%
S		SENTINELONE INCcl a	$10,714,000	+26.0%	200,000	0.0%	0.24%	+3.0%
	New	ENGAGESMART INC	$9,367,000	–	275,000	+100.0%	0.21%	–
HARP	Sell	HARPOON THERAPEUTICS INC	$9,406,000	-54.8%	1,190,600	-20.6%	0.21%	-63.0%
ACAD	Sell	ACADIA PHARMACEUTICALS INC	$9,136,000	-60.2%	550,000	-41.5%	0.20%	-67.4%
ORTX	Buy	ORCHARD THERAPEUTICS PLCads	$8,825,000	-46.8%	3,836,798	+1.5%	0.20%	-56.3%
CMAX	Buy	CAREMAX INC	$7,993,000	-24.2%	827,402	+1.2%	0.18%	-37.9%
ZETA		ZETA GLOBAL HOLDINGS CORPcl a	$7,618,000	-30.2%	1,300,000	0.0%	0.17%	-42.7%
TIL	Buy	INSTIL BIO INC	$7,296,000	-5.6%	408,140	+2.0%	0.16%	-22.5%
GLUE		MONTE ROSA THERAPEUTICS INC	$6,684,000	-1.9%	300,000	0.0%	0.15%	-19.6%
ONCS	Buy	ONCOSEC MED INC	$6,273,000	-20.3%	2,945,000	+5.2%	0.14%	-34.7%
TALS	Buy	TALARIS THERAPEUTICS INC	$6,170,000	-3.7%	455,000	+4.3%	0.14%	-20.8%
XLRN	Sell	ACCELERON PHARMA INC	$6,024,000	-86.6%	35,000	-90.2%	0.13%	-89.1%
KROS	New	KEROS THERAPEUTICS INC	$5,740,000	–	145,100	+100.0%	0.13%	–
ZIOP	New	ZIOPHARM ONCOLOGY INC	$5,460,000	–	3,000,000	+100.0%	0.12%	–
MSAC		MEDICUS SCIENCES ACQUISITION	$5,070,000	+1.0%	520,000	0.0%	0.11%	-17.6%
ARYD		ARYA SCIENCES ACQU CORP IVcl a	$5,025,000	-6.2%	500,000	0.0%	0.11%	-23.4%
HCAQ		HEALTHCOR CATALIO ACQU CORP	$4,950,000	+0.5%	500,000	0.0%	0.11%	-17.3%
DYNS		DYNAMICS SPECIAL PURPOSE COR	$4,970,000	0.0%	500,000	0.0%	0.11%	-17.9%
BLSA		BCLS ACQUISITION CORP	$4,980,000	-5.4%	500,000	0.0%	0.11%	-22.5%
PANA		PANACEA ACQUISITION CORP II	$4,885,000	-2.5%	500,000	0.0%	0.11%	-20.0%
	New	SOMALOGIC INC	$4,089,000	–	330,000	+100.0%	0.09%	–
HSAQ		HEALTH SCIENCES ACQ CORP 2	$3,956,000	-3.0%	400,000	0.0%	0.09%	-20.0%
LSAQ		LIFESCI ACQUISITION II CORP	$3,920,000	-2.0%	400,000	0.0%	0.09%	-19.4%
HLXA		HELIX ACQUISITION CORP	$3,940,000	-4.8%	400,000	0.0%	0.09%	-22.3%
	New	TANGO THERAPEUTICS INC	$3,879,000	–	300,000	+100.0%	0.09%	–
ZLAB	Sell	ZAI LAB LTDadr	$3,752,000	-78.8%	35,600	-64.4%	0.08%	-82.6%
NAUT	Sell	NAUTILUS BIOTECHNOLOGY INC	$3,684,000	-67.6%	600,000	-46.7%	0.08%	-73.3%
	New	SIGHT SCIENCES INC	$3,296,000	–	145,189	+100.0%	0.07%	–
ATAI	Sell	ATAI LIFE SCIENCES NV	$3,235,000	-50.2%	218,730	-37.7%	0.07%	-58.9%
KZR	New	KEZAR LIFE SCIENCES INC	$2,246,000	–	260,000	+100.0%	0.05%	–
DNAB		SOCIAL CAP SUVRETTA HLDS CRP	$1,976,000	-2.4%	200,000	0.0%	0.04%	-20.0%
DNAA		SOCIAL CAP SUVRETTA HLDS CRP	$1,990,000	-1.6%	200,000	0.0%	0.04%	-20.0%
DNAC		SOCIAL CAP SUVRETTA HLD CRPI	$1,960,000	-3.1%	200,000	0.0%	0.04%	-21.8%
DNAD		SOCIAL CAP SUVRETTA HLDS CP	$1,962,000	-2.9%	200,000	0.0%	0.04%	-21.8%
NUVBWS		NUVATION BIO INC*w exp 07/07/202	$253,000	-2.7%	99,999	0.0%	0.01%	-14.3%
	New	SOMALOGIC INC*w exp 03/01/202	$228,000	–	65,999	+100.0%	0.01%	–
MSACW		MEDICUS SCIENCES ACQUISITION*w exp 02/12/202	$41,000	-29.3%	57,770	0.0%	0.00%	-50.0%
NPCE	Exit	NEUROPACE INC	$0	–	-40,000	-100.0%	-0.03%	–
OMIC	Exit	SINGULAR GENOMICS SYSTEMS IN	$0	–	-50,000	-100.0%	-0.04%	–
CLVS	Exit	CLOVIS ONCOLOGY INC	$0	–	-271,726	-100.0%	-0.04%	–
FLYW	Exit	FLYWIRE CORPORATION	$0	–	-50,000	-100.0%	-0.05%	–
TKNO	Exit	ALPHA TEKNOVA INC	$0	–	-100,000	-100.0%	-0.06%	–
BCTG	Exit	BCTG ACQUISITION CORP	$0	–	-300,000	-100.0%	-0.09%	–
WKME	Exit	WALKME LTD	$0	–	-150,000	-100.0%	-0.12%	–
CMIIU	Exit	CM LIFE SCIENCES II INCunit 02/25/2028	$0	–	-330,000	-100.0%	-0.12%	–
CFLT	Exit	CONFLUENT INC	$0	–	-100,000	-100.0%	-0.13%	–
CELC	Exit	CELCUITY INC	$0	–	-200,000	-100.0%	-0.13%	–
FIGS	Exit	FIGS INCcl a	$0	–	-100,000	-100.0%	-0.14%	–
DNLI	Exit	DENALI THERAPEUTICS INC	$0	–	-86,100	-100.0%	-0.18%	–
CMLF	Exit	CM LIFE SCIENCES INC	$0	–	-525,000	-100.0%	-0.20%	–
PHVS	Exit	PHARVARIS N V	$0	–	-400,000	-100.0%	-0.20%	–
ESPR	Exit	ESPERION THERAPEUTICS INC NE	$0	–	-400,000	-100.0%	-0.23%	–
DOCS	Exit	DOXIMITY INCcl a	$0	–	-150,000	-100.0%	-0.24%	–
MNDY	Exit	MONDAY COM LTD	$0	–	-40,000	-100.0%	-0.24%	–
CRDF	Exit	CARDIFF ONCOLOGY INC	$0	–	-1,395,000	-100.0%	-0.25%	–
PRTA	Exit	PROTHENA CORP PLC	$0	–	-182,000	-100.0%	-0.25%	–
SYNH	Exit	SYNEOS HEALTH INCcl a	$0	–	-175,000	-100.0%	-0.42%	–
ALDX	Exit	ALDEYRA THERAPEUTICS INC	$0	–	-1,450,000	-100.0%	-0.44%	–
DVAX	Exit	DYNAVAX TECHNOLOGIES CORP	$0	–	-3,400,000	-100.0%	-0.90%	–
KDMN	Exit	KADMON HLDGS INC	$0	–	-9,294,600	-100.0%	-0.97%	–
CAH	Exit	CARDINAL HEALTH INC	$0	–	-654,200	-100.0%	-1.01%	–
	Exit	TRILLIUM THERAPEUTICS INC	$0	–	-4,105,000	-100.0%	-1.08%	–
BBIO	Exit	BRIDGEBIO PHARMA INC	$0	–	-673,400	-100.0%	-1.11%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-751,200	-100.0%	-1.48%	–
NEO	Exit	NEOGENOMICS INC	$0	–	-1,367,000	-100.0%	-1.67%	–
BIIB	Exit	BIOGEN INC	$0	–	-183,900	-100.0%	-1.72%	–
MDT	Exit	MEDTRONIC PLC	$0	–	-535,000	-100.0%	-1.80%	–
MRVI	Exit	MARAVAI LIFESCIENCES HLDGS I	$0	–	-2,963,545	-100.0%	-3.34%	–

Original filings

The following EDGAR filing(s) were analyzed to create this report:

View 13F-HR filed 2021-11-15

Signatures

The EDGAR filing(s) were signed by:

Jared Gandy — Chief Financial Officer/Chief Compliance Officer

Top long-term holdings

Name	Quarters owned	Latest quarter owned	Max weighting
NEUROCRINE BIOSCIENCES INC	15	Q3 2023	4.6%
ARVINAS INC	14	Q3 2023	4.9%
ZENTALIS PHARMACEUTICALS INC	14	Q3 2023	4.8%
SYNDAX PHARMACEUTICALS INC	14	Q3 2023	3.2%
IDEAYA BIOSCIENCES INC	13	Q3 2023	2.5%
NATERA INC	13	Q3 2023	1.9%
ALPINE IMMUNE SCIENCES INC	13	Q3 2023	0.5%
ABBVIE INC	12	Q2 2023	9.7%
HORIZON THERAPEUTICS PUB LTD	12	Q3 2022	3.4%
AVANTOR INC	11	Q1 2023	6.0%

View Avidity Partners Management LP's complete holdings history.

Latest significant ownerships (13-D/G)

Avidity Partners Management LP Q3 2021 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
	Filed	Shares	Percentage
Adicet Bio, Inc.^{Sold out}	February 14, 2023	0	0.0%
ALPINE IMMUNE SCIENCES, INC.	February 14, 2023	1,888,887	4.0%
ESSA Pharma Inc.	February 14, 2023	1,855,400	4.2%
Gritstone bio, Inc.	February 14, 2023	2,859,971	3.3%
IVERIC bio, Inc.	February 14, 2023	838,407	0.6%
ONCOSEC MEDICAL Inc^{Sold out}	February 14, 2023	0	0.0%
PhaseBio Pharmaceuticals Inc	February 14, 2023	2,040,000	4.1%
Phathom Pharmaceuticals, Inc.	February 14, 2023	1,900,000	4.6%
Viridian Therapeutics, Inc.^{Sold out}	February 14, 2023	0	0.0%
Anika Therapeutics, Inc.^{Sold out}	February 14, 2022	0	0.0%

View Avidity Partners Management LP's complete significant-ownership history.

Latest filings

Type	Filed
SC 13G	2024-04-09
SC 13G	2024-03-27
13F-HR	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-13
SC 13G/A	2024-02-13
SC 13G/A	2024-02-13

View Avidity Partners Management LP's complete filings history.

All filings

View complete filings history.

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