$4.71 Billion is the total value of Avidity Partners Management LP's 97 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 38.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ABBV | Buy | ABBVIE INC | $268,769,000 | +54.5% | 1,985,000 | +23.0% | 5.70% | +47.9% |
| ZNTL | Buy | ZENTALIS PHARMACEUTICALS INC | $228,223,000 | +37.3% | 2,715,000 | +8.9% | 4.84% | +31.5% |
| ARVN | Buy | ARVINAS INC | $207,648,000 | +13.1% | 2,527,973 | +13.1% | 4.40% | +8.2% |
| AVTR | Buy | AVANTOR INC | $201,935,000 | +52.0% | 4,792,000 | +47.6% | 4.28% | +45.5% |
| AZN | Buy | ASTRAZENECA PLCsponsored adr | $167,014,000 | +96.9% | 2,867,200 | +103.1% | 3.54% | +88.5% |
| BHVN | Buy | BIOHAVEN PHARMACTL HLDG CO L | $157,103,000 | +21.1% | 1,140,000 | +22.0% | 3.33% | +15.9% |
| BAX | Buy | BAXTER INTL INC | $151,508,000 | +118.5% | 1,765,000 | +104.8% | 3.21% | +109.2% |
| ANTM | New | ANTHEM INC | $148,796,000 | – | 321,000 | +100.0% | 3.16% | – |
| PFE | Buy | PFIZER INC | $123,415,000 | +179.5% | 2,090,000 | +103.5% | 2.62% | +167.7% |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $118,291,000 | -37.1% | 806,400 | -24.1% | 2.51% | -39.7% |
| ISEE | Buy | IVERIC BIO INC | $116,288,000 | +74.6% | 6,955,000 | +69.6% | 2.47% | +67.2% |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $115,603,000 | +78.4% | 535,000 | +52.4% | 2.45% | +70.9% |
| ARNA | Buy | ARENA PHARMACEUTICALS INC | $112,969,000 | +66.6% | 1,215,500 | +6.7% | 2.40% | +59.4% |
| HZNP | Buy | HORIZON THERAPEUTICS PUB L | $109,053,000 | +20.5% | 1,012,000 | +22.5% | 2.31% | +15.4% |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $107,314,000 | +31.8% | 1,260,000 | +48.4% | 2.28% | +26.2% |
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $106,574,000 | +24.6% | 995,000 | +19.6% | 2.26% | +19.3% |
| SGEN | Buy | SEAGEN INC | $105,901,000 | +16.1% | 685,000 | +27.6% | 2.25% | +11.2% |
| SNDX | SYNDAX PHARMACEUTICALS INC | $105,584,000 | +14.5% | 4,823,400 | 0.0% | 2.24% | +9.6% | |
| LLY | Buy | LILLY ELI & CO | $95,241,000 | +24.9% | 344,800 | +4.5% | 2.02% | +19.6% |
| CTLT | Buy | CATALENT INC | $88,981,000 | +68.0% | 695,000 | +74.6% | 1.89% | +60.9% |
| NTRA | Buy | NATERA INC | $87,787,000 | +23.3% | 940,000 | +47.2% | 1.86% | +18.1% |
| HOLX | Buy | HOLOGIC INC | $81,460,000 | +16.7% | 1,064,000 | +12.5% | 1.73% | +11.8% |
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS INC | $72,160,000 | +100.1% | 3,780,000 | +158.5% | 1.53% | +91.5% |
| SHC | Buy | SOTERA HEALTH CO | $69,708,000 | +12.1% | 2,960,000 | +24.5% | 1.48% | +7.3% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $62,745,000 | -22.2% | 370,000 | -13.3% | 1.33% | -25.5% |
| NUVB | Buy | NUVATION BIO INC | $62,751,000 | -13.1% | 7,382,488 | +1.6% | 1.33% | -16.8% |
| UNH | New | UNITEDHEALTH GROUP INC | $61,813,000 | – | 123,100 | +100.0% | 1.31% | – |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $61,488,000 | -63.4% | 280,000 | -69.8% | 1.30% | -65.0% |
| IDYA | Buy | IDEAYA BIOSCIENCES INC | $60,353,000 | -2.8% | 2,553,000 | +4.8% | 1.28% | -7.0% |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $58,863,000 | +43.4% | 700,000 | +53.8% | 1.25% | +37.3% |
| ARWR | Buy | ARROWHEAD PHARMACEUTICALS IN | $58,013,000 | +37.9% | 875,000 | +29.9% | 1.23% | +32.0% |
| STEVANATO GROUP S P A | $57,065,000 | -11.3% | 2,541,893 | 0.0% | 1.21% | -15.1% | ||
| GRTS | Sell | GRITSTONE BIO INC | $56,198,000 | +16.7% | 4,370,000 | -2.0% | 1.19% | +11.7% |
| KZR | Buy | KEZAR LIFE SCIENCES INC | $53,976,000 | +2303.2% | 3,228,200 | +1141.6% | 1.14% | +2190.0% |
| ACET | Buy | ADICET BIO INC | $53,065,000 | +179.7% | 3,034,004 | +25.4% | 1.12% | +167.9% |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $43,143,000 | +6.5% | 1,815,000 | +10.3% | 0.92% | +1.9% |
| KYMR | Buy | KYMERA THERAPEUTICS INC | $42,538,000 | +40.8% | 670,000 | +30.2% | 0.90% | +34.6% |
| IMCR | Buy | IMMUNOCORE HLDGS PLCads | $42,115,000 | +3.7% | 1,230,000 | +12.3% | 0.89% | -0.8% |
| Buy | CARIBOU BIOSCIENCES INC | $40,352,000 | -31.7% | 2,674,067 | +8.1% | 0.86% | -34.6% | |
| INSM | Buy | INSMED INC | $39,498,000 | +11.0% | 1,450,000 | +12.2% | 0.84% | +6.3% |
| OCDX | Sell | ORTHO CLINICAL DIAGNOSTICS H | $38,288,000 | -13.6% | 1,790,000 | -25.4% | 0.81% | -17.3% |
| PHAT | New | PHATHOM PHARMACEUTICALS INC | $37,294,000 | – | 1,896,000 | +100.0% | 0.79% | – |
| EPIX | Buy | ESSA PHARMA INC | $34,932,000 | +78.2% | 2,460,000 | +0.4% | 0.74% | +70.7% |
| AMN | New | AMN HEALTHCARE SVCS INC | $34,265,000 | – | 280,100 | +100.0% | 0.73% | – |
| LEGN | Sell | LEGEND BIOTECH CORPsponsored ads | $33,182,000 | -26.6% | 711,900 | -20.4% | 0.70% | -29.7% |
| ATEC | Sell | ALPHATEC HLDGS INC | $31,695,000 | -6.7% | 2,773,000 | -0.5% | 0.67% | -10.6% |
| BLU | Sell | BELLUS HEALTH INC NEW | $30,389,000 | +0.1% | 3,775,000 | -23.6% | 0.64% | -4.0% |
| VIR | Buy | VIR BIOTECHNOLOGY INC | $29,309,000 | +30.8% | 700,000 | +35.9% | 0.62% | +25.2% |
| AXSM | New | AXSOME THERAPEUTICS INC | $29,280,000 | – | 775,000 | +100.0% | 0.62% | – |
| SPNE | Buy | SEASPINE HLDGS CORP | $27,376,000 | -10.4% | 2,010,000 | +3.4% | 0.58% | -14.2% |
| ALT | Buy | ALTIMMUNE INC | $25,327,000 | +3.3% | 2,765,000 | +27.5% | 0.54% | -1.1% |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $25,271,000 | – | 1,278,261 | +100.0% | 0.54% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $25,231,000 | – | 862,000 | +100.0% | 0.54% | – |
| CCXI | New | CHEMOCENTRYX INC | $23,463,000 | – | 644,400 | +100.0% | 0.50% | – |
| SIBN | Buy | SI-BONE INC | $21,930,000 | +23.2% | 987,400 | +18.8% | 0.46% | +18.0% |
| CYT | Buy | CYTEIR THERAPEUTICS INC | $21,029,000 | -28.8% | 1,849,538 | +9.9% | 0.45% | -31.9% |
| ALPN | Sell | ALPINE IMMUNE SCIENCES INC | $18,628,000 | -9.6% | 1,345,000 | -30.4% | 0.40% | -13.6% |
| RLMD | New | RELMADA THERAPEUTICS INC | $16,482,000 | – | 731,536 | +100.0% | 0.35% | – |
| SCYX | Buy | SCYNEXIS INC | $13,660,000 | +25.1% | 2,239,278 | +8.7% | 0.29% | +19.8% |
| IPSC | Buy | CENTURY THERAPEUTICS INC | $13,505,000 | -27.4% | 851,522 | +15.2% | 0.29% | -30.6% |
| PHAS | PHASEBIO PHARMACEUTICALS INC | $11,497,000 | -16.1% | 4,405,000 | 0.0% | 0.24% | -19.7% | |
| New | HYPERFINE INC | $10,979,000 | – | 1,514,410 | +100.0% | 0.23% | – | |
| S | Buy | SENTINELONE INCcl a | $10,502,000 | -2.0% | 208,000 | +4.0% | 0.22% | -5.9% |
| GRPH | Sell | GRAPHITE BIO INC | $8,825,000 | -28.1% | 710,000 | -5.2% | 0.19% | -31.2% |
| Sell | FIELD TRIP HEALTH LTD | $7,884,000 | -52.0% | 3,205,000 | -10.5% | 0.17% | -54.1% | |
| Buy | TANGO THERAPEUTICS INC | $7,713,000 | +98.8% | 705,000 | +135.0% | 0.16% | +90.7% | |
| ACAD | Sell | ACADIA PHARMACEUTICALS INC | $7,002,000 | -23.4% | 300,000 | -45.5% | 0.15% | -26.2% |
| TIL | INSTIL BIO INC | $6,983,000 | -4.3% | 408,140 | 0.0% | 0.15% | -8.6% | |
| TALS | Buy | TALARIS THERAPEUTICS INC | $6,958,000 | +12.8% | 455,037 | +0.0% | 0.15% | +8.0% |
| New | DEFINITIVE HEALTHCARE CORP | $6,833,000 | – | 250,000 | +100.0% | 0.14% | – | |
| New | EQRX INC | $6,820,000 | – | 1,000,000 | +100.0% | 0.14% | – | |
| CMAX | CAREMAX INC | $6,354,000 | -20.5% | 827,402 | 0.0% | 0.14% | -23.7% | |
| CMPX | New | COMPASS THERAPEUTICS INC | $6,340,000 | – | 2,000,000 | +100.0% | 0.13% | – |
| GLUE | MONTE ROSA THERAPEUTICS INC | $6,126,000 | -8.3% | 300,000 | 0.0% | 0.13% | -12.2% | |
| HOWL | Sell | WEREWOLF THERAPEUTICS INC | $5,776,000 | -46.2% | 485,000 | -22.4% | 0.12% | -48.3% |
| MSAC | MEDICUS SCIENCES ACQUISITION | $5,039,000 | -0.6% | 520,000 | 0.0% | 0.11% | -4.5% | |
| DYNS | DYNAMICS SPECIAL PURPOSE COR | $4,930,000 | -0.8% | 500,000 | 0.0% | 0.10% | -4.5% | |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $4,958,000 | -1.3% | 500,000 | 0.0% | 0.10% | -5.4% | |
| BLSA | BCLS ACQUISITION CORP | $4,900,000 | -1.6% | 500,000 | 0.0% | 0.10% | -5.5% | |
| New | SCIENCE 37 HOLDINGS INC | $4,913,000 | – | 394,000 | +100.0% | 0.10% | – | |
| PANA | PANACEA ACQUISITION CORP II | $4,850,000 | -0.7% | 500,000 | 0.0% | 0.10% | -4.6% | |
| New | ENTRADA THERAPEUTICS INC | $4,366,000 | – | 255,000 | +100.0% | 0.09% | – | |
| Sell | SEMA4 HOLDINGS CORP | $4,237,000 | -66.4% | 950,000 | -42.8% | 0.09% | -67.7% | |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $4,032,000 | +1.9% | 400,000 | 0.0% | 0.09% | -2.3% | |
| HLXA | HELIX ACQUISITION CORP | $3,956,000 | +0.4% | 400,000 | 0.0% | 0.08% | -3.4% | |
| SOMALOGIC INC | $3,841,000 | -6.1% | 330,000 | 0.0% | 0.08% | -11.0% | ||
| MRUS | New | MERUS N V | $3,275,000 | – | 103,000 | +100.0% | 0.07% | – |
| ONCS | ONCOSEC MED INC | $2,826,000 | -54.9% | 2,945,000 | 0.0% | 0.06% | -56.8% | |
| DNAB | SOCIAL CAP SUVRETTA HLDS CRP | $1,978,000 | +0.1% | 200,000 | 0.0% | 0.04% | -4.5% | |
| DNAD | SOCIAL CAP SUVRETTA HLDS CP | $1,964,000 | +0.1% | 200,000 | 0.0% | 0.04% | -2.3% | |
| DNAC | SOCIAL CAP SUVRETTA HLD CRPI | $1,980,000 | +1.0% | 200,000 | 0.0% | 0.04% | -2.3% | |
| DNAA | SOCIAL CAP SUVRETTA HLDS CRP | $1,986,000 | -0.2% | 200,000 | 0.0% | 0.04% | -4.5% | |
| STTK | Sell | SHATTUCK LABS INC | $1,404,000 | -96.6% | 165,000 | -91.9% | 0.03% | -96.7% |
| ZIOP | Sell | ZIOPHARM ONCOLOGY INC | $643,000 | -88.2% | 590,000 | -80.3% | 0.01% | -88.4% |
| SOMALOGIC INC*w exp 08/31/202 | $220,000 | -3.5% | 65,999 | 0.0% | 0.01% | 0.0% | ||
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $189,000 | -25.3% | 99,999 | 0.0% | 0.00% | -33.3% | |
| MSACW | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $42,000 | +2.4% | 57,770 | 0.0% | 0.00% | 0.0% | |
| ATAI | Exit | ATAI LIFE SCIENCES NV | $0 | – | -218,730 | -100.0% | -0.07% | – |
| Exit | SIGHT SCIENCES INC | $0 | – | -145,189 | -100.0% | -0.07% | – | |
| NAUT | Exit | NAUTILUS BIOTECHNOLOGY INC | $0 | – | -600,000 | -100.0% | -0.08% | – |
| ZLAB | Exit | ZAI LAB LTDadr | $0 | – | -35,600 | -100.0% | -0.08% | – |
| LSAQ | Exit | LIFESCI ACQUISITION II CORP | $0 | – | -400,000 | -100.0% | -0.09% | – |
| HCAQ | Exit | HEALTHCOR CATALIO ACQU CORP | $0 | – | -500,000 | -100.0% | -0.11% | – |
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -145,100 | -100.0% | -0.13% | – |
| XLRN | Exit | ACCELERON PHARMA INC | $0 | – | -35,000 | -100.0% | -0.13% | – |
| ZETA | Exit | ZETA GLOBAL HOLDINGS CORPcl a | $0 | – | -1,300,000 | -100.0% | -0.17% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCads | $0 | – | -3,836,798 | -100.0% | -0.20% | – |
| HARP | Exit | HARPOON THERAPEUTICS INC | $0 | – | -1,190,600 | -100.0% | -0.21% | – |
| Exit | ENGAGESMART INC | $0 | – | -275,000 | -100.0% | -0.21% | – | |
| ACIU | Exit | AC IMMUNE SA | $0 | – | -1,739,600 | -100.0% | -0.26% | – |
| GHRS | Exit | GH RESEARCH PLCordinary shares | $0 | – | -560,000 | -100.0% | -0.27% | – |
| LFST | Exit | LIFESTANCE HEALTH GROUP INC | $0 | – | -1,000,000 | -100.0% | -0.32% | – |
| PATH | Exit | UIPATH INCcl a | $0 | – | -319,000 | -100.0% | -0.37% | – |
| SANA | Exit | SANA BIOTECHNOLOGY INC | $0 | – | -774,644 | -100.0% | -0.39% | – |
| IMAB | Exit | I MABsponsored ads | $0 | – | -454,000 | -100.0% | -0.73% | – |
| NTLA | Exit | INTELLIA THERAPEUTICS INC | $0 | – | -251,000 | -100.0% | -0.75% | – |
| CMPS | Exit | COMPASS PATHWAYS PLCsponsored ads | $0 | – | -1,162,000 | -100.0% | -0.77% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -369,000 | -100.0% | -0.78% | – |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -152,300 | -100.0% | -2.04% | – |
| XLRN | Exit | ACCELERON PHARMA INCcall | $0 | – | -1,228,100 | -100.0% | -4.68% | – |
| XBI | Exit | SPDR SER TRcall | $0 | – | -3,021,000 | -100.0% | -8.41% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-02-14
Signatures
The EDGAR filing(s) were signed by:
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| NEUROCRINE BIOSCIENCES INC | 15 | Q3 2023 | 4.6% |
| ARVINAS INC | 14 | Q3 2023 | 4.9% |
| ZENTALIS PHARMACEUTICALS INC | 14 | Q3 2023 | 4.8% |
| SYNDAX PHARMACEUTICALS INC | 14 | Q3 2023 | 3.2% |
| IDEAYA BIOSCIENCES INC | 13 | Q3 2023 | 2.5% |
| NATERA INC | 13 | Q3 2023 | 1.9% |
| ALPINE IMMUNE SCIENCES INC | 13 | Q3 2023 | 0.5% |
| ABBVIE INC | 12 | Q2 2023 | 9.7% |
| HORIZON THERAPEUTICS PUB LTD | 12 | Q3 2022 | 3.4% |
| AVANTOR INC | 11 | Q1 2023 | 6.0% |
View Avidity Partners Management LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Adicet Bio, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ALPINE IMMUNE SCIENCES, INC. | February 14, 2023 | 1,888,887 | 4.0% |
| ESSA Pharma Inc. | February 14, 2023 | 1,855,400 | 4.2% |
| Gritstone bio, Inc. | February 14, 2023 | 2,859,971 | 3.3% |
| IVERIC bio, Inc. | February 14, 2023 | 838,407 | 0.6% |
| ONCOSEC MEDICAL IncSold out | February 14, 2023 | 0 | 0.0% |
| PhaseBio Pharmaceuticals Inc | February 14, 2023 | 2,040,000 | 4.1% |
| Phathom Pharmaceuticals, Inc. | February 14, 2023 | 1,900,000 | 4.6% |
| Viridian Therapeutics, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Anika Therapeutics, Inc.Sold out | February 14, 2022 | 0 | 0.0% |
View Avidity Partners Management LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-04-09 |
| SC 13G | 2024-03-27 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-13 |
| SC 13G/A | 2024-02-13 |
| SC 13G/A | 2024-02-13 |
View Avidity Partners Management LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.