Avidity Partners Management LP

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$3.7 Billion is the total value of Avidity Partners Management LP's 112 reported holdings in Q2 2021. The portfolio turnover from Q1 2021 to Q2 2021 was 95.7% .

All

			Value		Shares		↓ Weighting
VRTX	Buy	VERTEX PHARMACEUTICALS INC.	$191,549,000	+186.7%	950,000	+205.6%	5.18%	+180.4%
ABBV	Sell	ABBVIE INC	$167,203,000	-25.6%	1,484,400	-28.5%	4.52%	-27.2%
ARVN	Buy	ARVINAS INC	$142,758,000	+22.7%	1,854,000	+5.3%	3.86%	+20.0%
LLY	New	LILLY ELI & CO	$129,794,000	–	565,500	+100.0%	3.51%	–
MRVI	Buy	MARAVAI LIFESCIENCES HLDGS I	$123,669,000	+25.7%	2,963,545	+7.3%	3.34%	+22.9%
MRTX	Buy	MIRATI THERAPEUTICS INC	$121,632,000	+49.3%	753,000	+58.3%	3.29%	+46.0%
ZNTL	Buy	ZENTALIS PHARMACEUTICALS INC	$114,912,000	+109.6%	2,160,000	+71.0%	3.11%	+105.2%
AVTR	Sell	AVANTOR INC	$112,922,000	-21.7%	3,180,000	-36.2%	3.05%	-23.4%
SGEN	Buy	SEAGEN INC	$101,043,000	+25.9%	640,000	+10.7%	2.73%	+23.2%
BHVN	Sell	BIOHAVEN PHARMACTL HLDG CO L	$85,673,000	+19.4%	882,500	-15.9%	2.32%	+16.9%
HOLX	New	HOLOGIC INC	$80,651,000	–	1,208,800	+100.0%	2.18%	–
SNDX	Buy	SYNDAX PHARMACEUTICALS INC	$79,240,000	-7.9%	4,615,000	+20.0%	2.14%	-9.8%
EPIX	Sell	ESSA PHARMA INC	$78,568,000	-4.8%	2,750,000	-3.2%	2.12%	-6.8%
EXAS	Sell	EXACT SCIENCES CORP	$73,343,000	-6.9%	590,000	-1.3%	1.98%	-9.0%
MDT	Sell	MEDTRONIC PLC	$66,410,000	-45.1%	535,000	-47.8%	1.80%	-46.3%
NBIX	Buy	NEUROCRINE BIOSCIENCES INC	$66,275,000	+30.7%	681,000	+30.6%	1.79%	+27.8%
NUVB	Sell	NUVATION BIO INC	$64,857,000	-17.5%	6,966,376	-7.4%	1.75%	-19.3%
ARNA	Buy	ARENA PHARMACEUTICALS INC	$64,313,000	+3.1%	943,000	+4.9%	1.74%	+0.9%
BIIB	New	BIOGEN INC	$63,679,000	–	183,900	+100.0%	1.72%	–
NEO	New	NEOGENOMICS INC	$61,747,000	–	1,367,000	+100.0%	1.67%	–
NTLA	New	INTELLIA THERAPEUTICS INC	$61,526,000	–	380,000	+100.0%	1.66%	–
IMAB	Sell	I MABsponsored ads	$61,200,000	-5.0%	729,000	-45.1%	1.65%	-7.1%
CTLT	Sell	CATALENT INC	$58,385,000	-1.0%	540,000	-3.6%	1.58%	-3.1%
STTK	Buy	SHATTUCK LABS INC	$56,246,000	+44.6%	1,940,200	+45.8%	1.52%	+41.4%
CNC	New	CENTENE CORP DEL	$54,785,000	–	751,200	+100.0%	1.48%	–
HZNP	Sell	HORIZON THERAPEUTICS PUB L	$53,188,000	-0.5%	568,000	-2.2%	1.44%	-2.6%
BPMC	Buy	BLUEPRINT MEDICINES CORP	$49,539,000	-6.7%	563,200	+3.2%	1.34%	-8.7%
NTRA	Buy	NATERA INC	$49,499,000	+23.2%	436,000	+10.2%	1.34%	+20.5%
SHC	Buy	SOTERA HEALTH CO	$46,279,000	+59.7%	1,910,000	+64.5%	1.25%	+56.2%
XLRN	Buy	ACCELERON PHARMA INC	$44,988,000	+2.8%	358,500	+11.1%	1.22%	+0.6%
IDYA	Buy	IDEAYA BIOSCIENCES INC	$43,449,000	+25.6%	2,070,000	+40.6%	1.17%	+22.8%
UTHR	New	UNITED THERAPEUTICS CORP DEL	$42,413,000	–	236,400	+100.0%	1.15%	–
BBIO	Sell	BRIDGEBIO PHARMA INC	$41,050,000	-18.2%	673,400	-17.4%	1.11%	-20.0%
ATEC	Buy	ALPHATEC HLDGS INC	$40,154,000	+9.0%	2,621,000	+12.3%	1.08%	+6.6%
	Buy	TRILLIUM THERAPEUTICS INC	$39,819,000	-7.7%	4,105,000	+2.2%	1.08%	-9.7%
CYT	New	CYTEIR THERAPEUTICS INC	$38,700,000	–	1,808,394	+100.0%	1.05%	–
CMPS	New	COMPASS PATHWAYS PLCsponsored ads	$38,150,000	–	1,000,000	+100.0%	1.03%	–
CAH	Sell	CARDINAL HEALTH INC	$37,348,000	-58.0%	654,200	-55.3%	1.01%	-58.9%
KDMN	Sell	KADMON HLDGS INC	$35,970,000	-3.1%	9,294,600	-2.6%	0.97%	-5.3%
DVAX	Sell	DYNAVAX TECHNOLOGIES CORP	$33,490,000	-2.7%	3,400,000	-2.9%	0.90%	-4.7%
ALNY	Sell	ALNYLAM PHARMACEUTICALS INC	$33,056,000	-45.3%	195,000	-54.4%	0.89%	-46.5%
INSM	New	INSMED INC	$32,730,000	–	1,150,050	+100.0%	0.88%	–
SPNE	New	SEASPINE HLDGS CORP	$31,278,000	–	1,524,998	+100.0%	0.84%	–
LFST	New	LIFESTANCE HEALTH GROUP INC	$30,646,000	–	1,100,000	+100.0%	0.83%	–
IPSC	New	CENTURY THERAPEUTICS INC	$29,443,000	–	1,003,522	+100.0%	0.80%	–
LEGN	New	LEGEND BIOTECH CORPsponsored ads	$25,656,000	–	625,000	+100.0%	0.69%	–
IMCR	Buy	IMMUNOCORE HLDGS PLCads	$23,469,000	+0.2%	601,000	+9.3%	0.63%	-2.0%
ACET	Buy	ADICET BIO INC	$23,158,000	-20.6%	2,250,500	+0.9%	0.63%	-22.3%
ACAD	New	ACADIA PHARMACEUTICALS INC	$22,927,000	–	940,000	+100.0%	0.62%	–
GRPH	New	GRAPHITE BIO INC	$22,602,000	–	735,500	+100.0%	0.61%	–
HARP	Buy	HARPOON THERAPEUTICS INC	$20,805,000	-29.4%	1,500,000	+6.5%	0.56%	-31.0%
PATH	New	UIPATH INCcl a	$20,379,000	–	300,000	+100.0%	0.55%	–
GRTS		GRITSTONE BIO INC	$19,374,000	-3.2%	2,122,064	0.0%	0.52%	-5.2%
SIBN	Sell	SI-BONE INC	$18,095,000	-1.5%	575,000	-0.4%	0.49%	-3.7%
ZLAB	New	ZAI LAB LTDadr	$17,699,000	–	100,000	+100.0%	0.48%	–
ORTX	Sell	ORCHARD THERAPEUTICS PLCads	$16,602,000	-47.0%	3,781,798	-12.4%	0.45%	-48.2%
ALDX	Sell	ALDEYRA THERAPEUTICS INC	$16,429,000	-45.8%	1,450,000	-43.2%	0.44%	-47.0%
PHAS	Buy	PHASEBIO PHARMACEUTICALS INC	$16,052,000	+8.3%	4,315,000	+0.7%	0.43%	+5.9%
SYNH	New	SYNEOS HEALTH INCcl a	$15,661,000	–	175,000	+100.0%	0.42%	–
SANA	Buy	SANA BIOTECHNOLOGY INC	$15,307,000	-37.6%	778,597	+6.3%	0.41%	-38.8%
SCYX	Buy	SCYNEXIS INC	$15,162,000	+51.1%	2,060,000	+63.0%	0.41%	+48.0%
ALPN	Sell	ALPINE IMMUNE SCIENCES INC	$13,455,000	-16.0%	1,495,000	-1.1%	0.36%	-17.6%
BLU	Sell	BELLUS HEALTH INC NEW	$13,218,000	-49.4%	4,250,000	-37.5%	0.36%	-50.5%
ACIU	New	AC IMMUNE SA	$12,561,000	–	1,584,000	+100.0%	0.34%	–
GHRS	New	GH RESEARCH PLCordinary shares	$12,169,000	–	560,000	+100.0%	0.33%	–
HOWL	New	WEREWOLF THERAPEUTICS INC	$11,341,000	–	650,265	+100.0%	0.31%	–
NAUT	New	NAUTILUS BIOTECHNOLOGY INC	$11,363,000	–	1,125,000	+100.0%	0.31%	–
ZETA	New	ZETA GLOBAL HOLDINGS CORPcl a	$10,920,000	–	1,300,000	+100.0%	0.30%	–
CMAX	New	CAREMAX INC	$10,544,000	–	817,402	+100.0%	0.28%	–
PRTA	New	PROTHENA CORP PLC	$9,357,000	–	182,000	+100.0%	0.25%	–
CRDF	Sell	CARDIFF ONCOLOGY INC	$9,277,000	-59.1%	1,395,000	-43.0%	0.25%	-59.9%
MNDY	New	MONDAY COM LTD	$8,944,000	–	40,000	+100.0%	0.24%	–
ISEE	New	IVERIC BIO INC	$8,834,000	–	1,400,010	+100.0%	0.24%	–
DOCS	New	DOXIMITY INCcl a	$8,730,000	–	150,000	+100.0%	0.24%	–
ARWR	New	ARROWHEAD PHARMACEUTICALS IN	$8,613,000	–	104,000	+100.0%	0.23%	–
S	New	SENTINELONE INCcl a	$8,500,000	–	200,000	+100.0%	0.23%	–
ESPR	New	ESPERION THERAPEUTICS INC NE	$8,460,000	–	400,000	+100.0%	0.23%	–
ONCS	Sell	ONCOSEC MED INC	$7,868,000	-52.5%	2,800,000	-19.3%	0.21%	-53.4%
TIL		INSTIL BIO INC	$7,728,000	-23.0%	400,000	0.0%	0.21%	-24.5%
VIR	New	VIR BIOTECHNOLOGY INC	$7,659,000	–	162,000	+100.0%	0.21%	–
PHVS		PHARVARIS N V	$7,452,000	-33.4%	400,000	0.0%	0.20%	-35.0%
CMLF	Sell	CM LIFE SCIENCES INC	$7,355,000	-10.2%	525,000	-4.5%	0.20%	-11.9%
GLUE	New	MONTE ROSA THERAPEUTICS INC	$6,810,000	–	300,000	+100.0%	0.18%	–
DNLI	New	DENALI THERAPEUTICS INC	$6,754,000	–	86,100	+100.0%	0.18%	–
ATAI	New	ATAI LIFE SCIENCES NV	$6,493,000	–	350,987	+100.0%	0.18%	–
TALS	New	TALARIS THERAPEUTICS INC	$6,410,000	–	436,363	+100.0%	0.17%	–
ARYD		ARYA SCIENCES ACQU CORP IVcl a	$5,360,000	+2.4%	500,000	0.0%	0.14%	0.0%
BLSA		BCLS ACQUISITION CORP	$5,265,000	-0.4%	500,000	0.0%	0.14%	-2.7%
MSAC	New	MEDICUS SCIENCES ACQUISITION	$5,018,000	–	520,000	+100.0%	0.14%	–
FIGS	New	FIGS INCcl a	$5,010,000	–	100,000	+100.0%	0.14%	–
PANA	New	PANACEA ACQUISITION CORP II	$5,008,000	–	500,000	+100.0%	0.14%	–
DYNS	New	DYNAMICS SPECIAL PURPOSE COR	$4,970,000	–	500,000	+100.0%	0.13%	–
HCAQ		HEALTHCOR CATALIO ACQU CORP	$4,925,000	-1.5%	500,000	0.0%	0.13%	-3.6%
CELC	New	CELCUITY INC	$4,800,000	–	200,000	+100.0%	0.13%	–
CFLT	New	CONFLUENT INC	$4,750,000	–	100,000	+100.0%	0.13%	–
CMIIU	Sell	CM LIFE SCIENCES II INCunit 02/25/2028	$4,439,000	+3.0%	330,000	-2.0%	0.12%	+0.8%
WKME	New	WALKME LTD	$4,389,000	–	150,000	+100.0%	0.12%	–
HLXA		HELIX ACQUISITION CORP	$4,140,000	+1.5%	400,000	0.0%	0.11%	-0.9%
HSAQ		HEALTH SCIENCES ACQ CORP 2	$4,080,000	-8.8%	400,000	0.0%	0.11%	-11.3%
LSAQ		LIFESCI ACQUISITION II CORP	$4,000,000	-1.4%	400,000	0.0%	0.11%	-3.6%
BCTG		BCTG ACQUISITION CORP	$3,414,000	+2.3%	300,000	0.0%	0.09%	0.0%
TKNO	New	ALPHA TEKNOVA INC	$2,373,000	–	100,000	+100.0%	0.06%	–
DNAB	New	SOCIAL CAP SUVRETTA HLDS CRP	$2,024,000	–	200,000	+100.0%	0.06%	–
DNAA	New	SOCIAL CAP SUVRETTA HLDS CRP	$2,022,000	–	200,000	+100.0%	0.06%	–
DNAC	New	SOCIAL CAP SUVRETTA HLD CRPI	$2,022,000	–	200,000	+100.0%	0.06%	–
DNAD	New	SOCIAL CAP SUVRETTA HLDS CP	$2,020,000	–	200,000	+100.0%	0.06%	–
FLYW	New	FLYWIRE CORPORATION	$1,837,000	–	50,000	+100.0%	0.05%	–
CLVS	New	CLOVIS ONCOLOGY INC	$1,576,000	–	271,726	+100.0%	0.04%	–
OMIC	New	SINGULAR GENOMICS SYSTEMS IN	$1,374,000	–	50,000	+100.0%	0.04%	–
NPCE	New	NEUROPACE INC	$952,000	–	40,000	+100.0%	0.03%	–
NUVBWS		NUVATION BIO INC*w exp 07/07/202	$260,000	-2.6%	99,999	0.0%	0.01%	0.0%
MSACW	New	MEDICUS SCIENCES ACQUISITION*w exp 02/12/202	$58,000	–	57,770	+100.0%	0.00%	–
AMWL	Exit	AMERICAN WELL CORPcl a	$0	–	-70,250	-100.0%	-0.03%	–
ANNX	Exit	ANNEXON INC	$0	–	-70,000	-100.0%	-0.05%	–
EYPT	Exit	EYEPOINT PHARMACEUTICALS INC	$0	–	-232,504	-100.0%	-0.06%	–
COGT	Exit	COGENT BIOSCIENCES INC	$0	–	-417,710	-100.0%	-0.10%	–
MSACU	Exit	MEDICUS SCIENCES ACQUISITIONunit 99/99/9999	$0	–	-520,000	-100.0%	-0.14%	–
ARGX	Exit	ARGENX SEsponsored adr	$0	–	-20,000	-100.0%	-0.15%	–
ARYA	Exit	ARYA SCIENCES ACQUISITION CO	$0	–	-500,000	-100.0%	-0.19%	–
VSPRU	Exit	VESPER HEALTHCARE ACQSTN CORunit 99/99/9999	$0	–	-600,000	-100.0%	-0.19%	–
EVLO	Exit	EVELO BIOSCIENCES INC	$0	–	-800,000	-100.0%	-0.24%	–
TERN	Exit	TERNS PHARMACEUTICALS INC	$0	–	-400,000	-100.0%	-0.24%	–
IMTX	Exit	IMMATICS N.V	$0	–	-884,600	-100.0%	-0.27%	–
MRUS	Exit	MERUS N V	$0	–	-487,000	-100.0%	-0.28%	–
AFMD	Exit	AFFIMED N V	$0	–	-1,296,000	-100.0%	-0.28%	–
ADMS	Exit	ADAMAS PHARMACEUTICALS INC	$0	–	-2,200,200	-100.0%	-0.29%	–
KZR	Exit	KEZAR LIFE SCIENCES INC	$0	–	-1,907,081	-100.0%	-0.31%	–
COLL	Exit	COLLEGIUM PHARMACEUTICAL INC	$0	–	-740,000	-100.0%	-0.48%	–
SGTX	Exit	SIGILON THERAPEUTICS INC	$0	–	-850,968	-100.0%	-0.52%	–
BVS	Exit	BIOVENTUS INC	$0	–	-1,254,333	-100.0%	-0.53%	–
CMRX	Exit	CHIMERIX INC	$0	–	-2,230,000	-100.0%	-0.59%	–
BOLT	Exit	BOLT BIOTHERAPEUTICS INC	$0	–	-654,294	-100.0%	-0.60%	–
IGMS	Exit	IGM BIOSCIENCES INC	$0	–	-293,000	-100.0%	-0.62%	–
AUPH	Exit	AURINIA PHARMACEUTICALS INC	$0	–	-1,784,000	-100.0%	-0.64%	–
CRIS	Exit	CURIS INC	$0	–	-2,053,789	-100.0%	-0.64%	–
KNSA	Exit	KINIKSA PHARMACEUTICALS LTD	$0	–	-1,330,700	-100.0%	-0.68%	–
ORGO	Exit	ORGANOGENESIS HLDGS INC	$0	–	-1,463,403	-100.0%	-0.74%	–
CGEM	Exit	CULLINAN ONCOLOGY INC	$0	–	-707,359	-100.0%	-0.81%	–
ATHA	Exit	ATHIRA PHARMA INC	$0	–	-1,677,845	-100.0%	-0.85%	–
CI	Exit	CIGNA CORP NEW	$0	–	-135,000	-100.0%	-0.90%	–
	Exit	BIOHAVEN PHARMACTL HLDG CO Lcall	$0	–	-523,100	-100.0%	-0.99%	–
INO	Exit	INOVIO PHARMACEUTICALS INC	$0	–	-4,004,391	-100.0%	-1.03%	–
ABMD	Exit	ABIOMED INC	$0	–	-132,500	-100.0%	-1.17%	–
CCXI	Exit	CHEMOCENTRYX INC	$0	–	-940,800	-100.0%	-1.33%	–
ZBH	Exit	ZIMMER BIOMET HOLDINGS INC	$0	–	-326,000	-100.0%	-1.44%	–
BHC	Exit	BAUSCH HEALTH COS INC	$0	–	-1,891,300	-100.0%	-1.66%	–
ISRG	Exit	INTUITIVE SURGICAL INC	$0	–	-139,400	-100.0%	-2.85%	–
AZN	Exit	ASTRAZENECA PLCsponsored adr	$0	–	-3,650,500	-100.0%	-5.01%	–

Original filings

The following EDGAR filing(s) were analyzed to create this report:

View 13F-HR filed 2021-08-16

Signatures

The EDGAR filing(s) were signed by:

Jared Gandy — Chief Financial Officer/Chief Compliance Officer

Top long-term holdings

Name	Quarters owned	Latest quarter owned	Max weighting
NEUROCRINE BIOSCIENCES INC	15	Q3 2023	4.6%
ARVINAS INC	14	Q3 2023	4.9%
ZENTALIS PHARMACEUTICALS INC	14	Q3 2023	4.8%
SYNDAX PHARMACEUTICALS INC	14	Q3 2023	3.2%
IDEAYA BIOSCIENCES INC	13	Q3 2023	2.5%
NATERA INC	13	Q3 2023	1.9%
ALPINE IMMUNE SCIENCES INC	13	Q3 2023	0.5%
ABBVIE INC	12	Q2 2023	9.7%
HORIZON THERAPEUTICS PUB LTD	12	Q3 2022	3.4%
AVANTOR INC	11	Q1 2023	6.0%

View Avidity Partners Management LP's complete holdings history.

Latest significant ownerships (13-D/G)

Avidity Partners Management LP Q2 2021 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
	Filed	Shares	Percentage
Adicet Bio, Inc.^{Sold out}	February 14, 2023	0	0.0%
ALPINE IMMUNE SCIENCES, INC.	February 14, 2023	1,888,887	4.0%
ESSA Pharma Inc.	February 14, 2023	1,855,400	4.2%
Gritstone bio, Inc.	February 14, 2023	2,859,971	3.3%
IVERIC bio, Inc.	February 14, 2023	838,407	0.6%
ONCOSEC MEDICAL Inc^{Sold out}	February 14, 2023	0	0.0%
PhaseBio Pharmaceuticals Inc	February 14, 2023	2,040,000	4.1%
Phathom Pharmaceuticals, Inc.	February 14, 2023	1,900,000	4.6%
Viridian Therapeutics, Inc.^{Sold out}	February 14, 2023	0	0.0%
Anika Therapeutics, Inc.^{Sold out}	February 14, 2022	0	0.0%

View Avidity Partners Management LP's complete significant-ownership history.

Latest filings

Type	Filed
SC 13G	2024-04-09
SC 13G	2024-03-27
13F-HR	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-13
SC 13G/A	2024-02-13
SC 13G/A	2024-02-13

View Avidity Partners Management LP's complete filings history.

All filings

View complete filings history.

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