$3.62 Billion is the total value of Avidity Partners Management LP's 94 reported holdings in Q1 2021. The portfolio turnover from Q4 2020 to Q1 2021 was 79.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ABBV | Buy | ABBVIE INC | $224,795,000 | +54.7% | 2,077,200 | +53.2% | 6.21% | +31.7% |
| AZN | Buy | ASTRAZENECA PLCsponsored adr | $181,503,000 | +57.9% | 3,650,500 | +58.7% | 5.01% | +34.3% |
| AVTR | Sell | AVANTOR INC | $144,219,000 | -22.0% | 4,985,100 | -24.1% | 3.98% | -33.6% |
| MDT | Buy | MEDTRONIC PLC | $120,989,000 | +243.1% | 1,024,200 | +240.3% | 3.34% | +191.9% |
| ARVN | Sell | ARVINAS INC | $116,356,000 | -23.3% | 1,760,300 | -1.5% | 3.21% | -34.8% |
| ISRG | New | INTUITIVE SURGICAL INC | $103,008,000 | – | 139,400 | +100.0% | 2.85% | – |
| MRVI | Sell | MARAVAI LIFESCIENCES HLDGS I | $98,421,000 | +1.8% | 2,761,545 | -19.9% | 2.72% | -13.4% |
| CAH | Buy | CARDINAL HEALTH INC | $88,877,000 | +105.4% | 1,463,000 | +81.1% | 2.46% | +74.7% |
| SNDX | Buy | SYNDAX PHARMACEUTICALS INC | $85,997,000 | +16.9% | 3,846,000 | +16.3% | 2.38% | -0.5% |
| EPIX | Buy | ESSA PHARMA INC | $82,502,000 | +170.3% | 2,840,000 | +11.0% | 2.28% | +130.0% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $81,487,000 | -2.4% | 475,700 | +25.2% | 2.25% | -16.9% |
| SGEN | New | SEAGEN INC | $80,247,000 | – | 577,900 | +100.0% | 2.22% | – |
| EXAS | Buy | EXACT SCIENCES CORP | $78,804,000 | +140.8% | 598,000 | +142.1% | 2.18% | +105.0% |
| NUVB | New | NUVATION BIO INC | $78,604,000 | – | 7,521,941 | +100.0% | 2.17% | – |
| BHVN | Buy | BIOHAVEN PHARMACTL HLDG CO L | $71,754,000 | +70.2% | 1,049,800 | +113.5% | 1.98% | +44.9% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $66,809,000 | +91.9% | 310,900 | +111.1% | 1.85% | +63.4% |
| IMAB | Sell | I MABsponsored ads | $64,417,000 | -14.1% | 1,329,000 | -16.5% | 1.78% | -26.9% |
| ARNA | Buy | ARENA PHARMACEUTICALS INC | $62,350,000 | +30.7% | 898,550 | +44.7% | 1.72% | +11.2% |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $60,425,000 | – | 427,969 | +100.0% | 1.67% | – |
| BHC | Sell | BAUSCH HEALTH COS INC | $60,030,000 | +46.4% | 1,891,300 | -4.1% | 1.66% | +24.5% |
| CTLT | Buy | CATALENT INC | $58,974,000 | +68.2% | 560,000 | +66.2% | 1.63% | +43.0% |
| ZNTL | Buy | ZENTALIS PHARMACEUTICALS INC | $54,815,000 | -7.0% | 1,263,300 | +11.3% | 1.51% | -20.9% |
| HZNP | Sell | HORIZON THERAPEUTICS PUB L | $53,475,000 | -37.5% | 581,000 | -50.3% | 1.48% | -46.8% |
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $53,088,000 | +97.2% | 546,000 | +127.5% | 1.47% | +67.8% |
| ZBH | New | ZIMMER BIOMET HOLDINGS INC | $52,186,000 | – | 326,000 | +100.0% | 1.44% | – |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $50,706,000 | +76.3% | 521,400 | +73.8% | 1.40% | +50.0% |
| BBIO | New | BRIDGEBIO PHARMA INC | $50,210,000 | – | 815,100 | +100.0% | 1.39% | – |
| CCXI | Buy | CHEMOCENTRYX INC | $48,207,000 | +2.8% | 940,800 | +24.3% | 1.33% | -12.5% |
| XLRN | Buy | ACCELERON PHARMA INC | $43,775,000 | +14.4% | 322,800 | +8.0% | 1.21% | -2.7% |
| Buy | TRILLIUM THERAPEUTICS INC | $43,121,000 | -8.0% | 4,015,000 | +26.1% | 1.19% | -21.7% | |
| ABMD | New | ABIOMED INC | $42,232,000 | – | 132,500 | +100.0% | 1.17% | – |
| NTRA | Sell | NATERA INC | $40,169,000 | -15.9% | 395,600 | -17.5% | 1.11% | -28.4% |
| STTK | Buy | SHATTUCK LABS INC | $38,900,000 | -20.9% | 1,330,385 | +41.7% | 1.08% | -32.7% |
| INO | New | INOVIO PHARMACEUTICALS INC | $37,161,000 | – | 4,004,391 | +100.0% | 1.03% | – |
| KDMN | Sell | KADMON HLDGS INC | $37,127,000 | -6.5% | 9,544,200 | -0.3% | 1.03% | -20.4% |
| ATEC | Buy | ALPHATEC HLDGS INC | $36,854,000 | +37.1% | 2,334,000 | +26.1% | 1.02% | +16.6% |
| New | BIOHAVEN PHARMACTL HLDG CO Lcall | $35,754,000 | – | 523,100 | +100.0% | 0.99% | – | |
| IDYA | New | IDEAYA BIOSCIENCES INC | $34,592,000 | – | 1,472,000 | +100.0% | 0.96% | – |
| DVAX | Sell | DYNAVAX TECHNOLOGIES CORP | $34,405,000 | +93.3% | 3,500,000 | -12.5% | 0.95% | +64.4% |
| CI | New | CIGNA CORP NEW | $32,635,000 | – | 135,000 | +100.0% | 0.90% | – |
| ORTX | New | ORCHARD THERAPEUTICS PLCads | $31,347,000 | – | 4,317,800 | +100.0% | 0.87% | – |
| ATHA | Buy | ATHIRA PHARMA INC | $30,872,000 | -13.7% | 1,677,845 | +60.7% | 0.85% | -26.5% |
| ALDX | Buy | ALDEYRA THERAPEUTICS INC | $30,318,000 | +208.0% | 2,552,000 | +77.8% | 0.84% | +161.9% |
| CGEM | New | CULLINAN ONCOLOGY INC | $29,476,000 | – | 707,359 | +100.0% | 0.81% | – |
| HARP | Buy | HARPOON THERAPEUTICS INC | $29,455,000 | +125.9% | 1,408,000 | +79.4% | 0.81% | +92.4% |
| ACET | New | ADICET BIO INC | $29,168,000 | – | 2,230,000 | +100.0% | 0.81% | – |
| SHC | Buy | SOTERA HEALTH CO | $28,979,000 | +50.9% | 1,161,000 | +65.9% | 0.80% | +28.4% |
| ORGO | Sell | ORGANOGENESIS HLDGS INC | $26,663,000 | -35.9% | 1,463,403 | -73.5% | 0.74% | -45.4% |
| BLU | Buy | BELLUS HEALTH INC NEW | $26,102,000 | +49.0% | 6,797,400 | +18.7% | 0.72% | +26.7% |
| KNSA | Buy | KINIKSA PHARMACEUTICALS LTD | $24,631,000 | +44.4% | 1,330,700 | +37.9% | 0.68% | +22.7% |
| SANA | New | SANA BIOTECHNOLOGY INC | $24,511,000 | – | 732,321 | +100.0% | 0.68% | – |
| IMCR | New | IMMUNOCORE HLDGS PLCads | $23,414,000 | – | 550,000 | +100.0% | 0.65% | – |
| CRIS | Sell | CURIS INC | $23,249,000 | +21.2% | 2,053,789 | -12.3% | 0.64% | +3.0% |
| AUPH | Sell | AURINIA PHARMACEUTICALS INC | $23,165,000 | -16.3% | 1,784,000 | -10.8% | 0.64% | -28.7% |
| CRDF | Buy | CARDIFF ONCOLOGY INC | $22,666,000 | -21.6% | 2,447,700 | +52.3% | 0.63% | -33.3% |
| IGMS | Buy | IGM BIOSCIENCES INC | $22,470,000 | +218.1% | 293,000 | +266.2% | 0.62% | +171.2% |
| BOLT | New | BOLT BIOTHERAPEUTICS INC | $21,533,000 | – | 654,294 | +100.0% | 0.60% | – |
| CMRX | New | CHIMERIX INC | $21,497,000 | – | 2,230,000 | +100.0% | 0.59% | – |
| GRTS | GRITSTONE ONCOLOGY INC | $20,011,000 | +139.3% | 2,122,064 | 0.0% | 0.55% | +104.1% | |
| BVS | New | BIOVENTUS INC | $19,166,000 | – | 1,254,333 | +100.0% | 0.53% | – |
| SGTX | Buy | SIGILON THERAPEUTICS INC | $19,019,000 | -42.4% | 850,968 | +23.7% | 0.52% | -51.1% |
| SIBN | Sell | SI BONE INC | $18,373,000 | -4.0% | 577,570 | -9.7% | 0.51% | -18.2% |
| COLL | Sell | COLLEGIUM PHARMACEUTICAL INC | $17,538,000 | -29.3% | 740,000 | -40.3% | 0.48% | -39.8% |
| ONCS | Buy | ONCOSEC MED INC | $16,552,000 | +31.5% | 3,470,000 | +77.8% | 0.46% | +11.7% |
| ALPN | Buy | ALPINE IMMUNE SCIENCES INC | $16,017,000 | +1.9% | 1,511,000 | +21.1% | 0.44% | -13.5% |
| PHAS | New | PHASEBIO PHARMACEUTICALS INC | $14,826,000 | – | 4,285,000 | +100.0% | 0.41% | – |
| KZR | New | KEZAR LIFE SCIENCES INC | $11,366,000 | – | 1,907,081 | +100.0% | 0.31% | – |
| PHVS | New | PHARVARIS N V | $11,192,000 | – | 400,000 | +100.0% | 0.31% | – |
| ADMS | New | ADAMAS PHARMACEUTICALS INC | $10,561,000 | – | 2,200,200 | +100.0% | 0.29% | – |
| AFMD | New | AFFIMED N V | $10,251,000 | – | 1,296,000 | +100.0% | 0.28% | – |
| MRUS | New | MERUS N V | $10,173,000 | – | 487,000 | +100.0% | 0.28% | – |
| SCYX | Buy | SCYNEXIS INC | $10,034,000 | +4.5% | 1,263,769 | +0.7% | 0.28% | -11.2% |
| TIL | New | INSTIL BIO INC | $10,032,000 | – | 400,000 | +100.0% | 0.28% | – |
| IMTX | New | IMMATICS N.V | $9,916,000 | – | 884,600 | +100.0% | 0.27% | – |
| TERN | New | TERNS PHARMACEUTICALS INC | $8,800,000 | – | 400,000 | +100.0% | 0.24% | – |
| EVLO | New | EVELO BIOSCIENCES INC | $8,560,000 | – | 800,000 | +100.0% | 0.24% | – |
| CMLF | New | CM LIFE SCIENCES INC | $8,190,000 | – | 550,000 | +100.0% | 0.23% | – |
| VSPRU | VESPER HEALTHCARE ACQSTN CORunit 99/99/9999 | $6,930,000 | -4.7% | 600,000 | 0.0% | 0.19% | -19.1% | |
| ARYA | ARYA SCIENCES ACQUISITION CO | $6,890,000 | +27.0% | 500,000 | 0.0% | 0.19% | +8.0% | |
| ARGX | New | ARGENX SEsponsored adr | $5,508,000 | – | 20,000 | +100.0% | 0.15% | – |
| BLSA | BCLS ACQUISITION CORP | $5,285,000 | -5.1% | 500,000 | 0.0% | 0.15% | -19.3% | |
| ARYD | New | ARYA SCIENCES ACQU CORP IVcl a | $5,236,000 | – | 500,000 | +100.0% | 0.14% | – |
| MSACU | New | MEDICUS SCIENCES ACQUISITIONunit 99/99/9999 | $5,122,000 | – | 520,000 | +100.0% | 0.14% | – |
| HCAQ | New | HEALTHCOR CATALIO ACQU CORP | $5,000,000 | – | 500,000 | +100.0% | 0.14% | – |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $4,476,000 | -12.6% | 400,000 | 0.0% | 0.12% | -25.3% | |
| CMIIU | New | CM LIFE SCIENCES II INCunit 02/25/2028 | $4,310,000 | – | 336,700 | +100.0% | 0.12% | – |
| HLXA | HELIX ACQUISITION CORP | $4,080,000 | -10.3% | 400,000 | 0.0% | 0.11% | -23.6% | |
| LSAQ | LIFESCI ACQUISITION II CORP | $4,056,000 | -5.0% | 400,000 | 0.0% | 0.11% | -19.4% | |
| COGT | Sell | COGENT BIOSCIENCES INC | $3,667,000 | -37.2% | 417,710 | -19.6% | 0.10% | -46.6% |
| BCTG | BCTG ACQUISITION CORP | $3,336,000 | -2.8% | 300,000 | 0.0% | 0.09% | -17.1% | |
| EYPT | New | EYEPOINT PHARMACEUTICALS INC | $2,362,000 | – | 232,504 | +100.0% | 0.06% | – |
| ANNX | ANNEXON INC | $1,949,000 | +11.2% | 70,000 | 0.0% | 0.05% | -5.3% | |
| AMWL | Buy | AMERICAN WELL CORPcl a | $1,220,000 | -3.7% | 70,250 | +40.5% | 0.03% | -17.1% |
| NUVBWS | New | NUVATION BIO INC*w exp 07/07/202 | $267,000 | – | 99,999 | +100.0% | 0.01% | – |
| INZY | Exit | INOZYME PHARMA INC | $0 | – | -9,683 | -100.0% | -0.01% | – |
| RLAY | Exit | RELAY THERAPEUTICS INC | $0 | – | -30,000 | -100.0% | -0.04% | – |
| NRIX | Exit | NURIX THERAPEUTICS INC | $0 | – | -50,000 | -100.0% | -0.05% | – |
| BCAB | Exit | BIOATLA INC | $0 | – | -50,000 | -100.0% | -0.06% | – |
| ACCD | Exit | ACCOLADE INC | $0 | – | -40,000 | -100.0% | -0.06% | – |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -50,000 | -100.0% | -0.09% | – |
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -40,000 | -100.0% | -0.09% | – |
| ITOS | Exit | ITEOS THERAPEUTICS INC | $0 | – | -92,574 | -100.0% | -0.10% | – |
| PANAU | Exit | PANACEA ACQUISITION CORPunit 99/99/9999 | $0 | – | -300,000 | -100.0% | -0.12% | – |
| ALBO | Exit | ALBIREO PHARMA INC | $0 | – | -125,000 | -100.0% | -0.15% | – |
| PHAT | Exit | PHATHOM PHARMACEUTICALS INC | $0 | – | -152,500 | -100.0% | -0.16% | – |
| FPRX | Exit | FIVE PRIME THERAPEUTICS INC | $0 | – | -300,000 | -100.0% | -0.17% | – |
| OCUL | Exit | OCULAR THERAPEUTIX INC | $0 | – | -250,000 | -100.0% | -0.17% | – |
| OM | Exit | OUTSET MED INC | $0 | – | -100,000 | -100.0% | -0.18% | – |
| LGND | Exit | LIGAND PHARMACEUTICALS INC | $0 | – | -62,100 | -100.0% | -0.20% | – |
| OSH | Exit | OAK STR HEALTH INC | $0 | – | -150,000 | -100.0% | -0.30% | – |
| CSTL | Exit | CASTLE BIOSCIENCES INC | $0 | – | -150,000 | -100.0% | -0.33% | – |
| TSHA | Exit | TAYSHA GENE THERAPIES INC | $0 | – | -392,000 | -100.0% | -0.34% | – |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -347,645 | -100.0% | -0.37% | – |
| OLMA | Exit | OLEMA PHARMACEUTICALS INC | $0 | – | -270,000 | -100.0% | -0.42% | – |
| CDXS | Exit | CODEXIS INC | $0 | – | -600,000 | -100.0% | -0.42% | – |
| STRO | Exit | SUTRO BIOPHARMA INC | $0 | – | -626,000 | -100.0% | -0.44% | – |
| CERT | Exit | CERTARA INC | $0 | – | -404,663 | -100.0% | -0.44% | – |
| SGRY | Exit | SURGERY PARTNERS INC | $0 | – | -531,000 | -100.0% | -0.50% | – |
| RETA | Exit | REATA PHARMACEUTICALS INCcl a | $0 | – | -125,690 | -100.0% | -0.50% | – |
| NTLA | Exit | INTELLIA THERAPEUTICS INC | $0 | – | -303,000 | -100.0% | -0.54% | – |
| ATRC | Exit | ATRICURE INC | $0 | – | -446,600 | -100.0% | -0.81% | – |
| BTAI | Exit | BIOXCEL THERAPEUTICS INC | $0 | – | -547,000 | -100.0% | -0.82% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -578,100 | -100.0% | -0.89% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -527,600 | -100.0% | -0.92% | – |
| ANIK | Exit | ANIKA THERAPEUTICS INC | $0 | – | -731,000 | -100.0% | -1.07% | – |
| SRPT | Exit | SAREPTA TEHRAPEUTICS INC | $0 | – | -217,400 | -100.0% | -1.20% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -774,000 | -100.0% | -1.44% | – |
| BHVN | Exit | BIOHAVEN PHARMACTL HLDG CO Lcall | $0 | – | -521,100 | -100.0% | -1.45% | – |
| CHNG | Exit | CHANGE HEALTHCARE INC | $0 | – | -3,082,100 | -100.0% | -1.87% | – |
| Exit | BIOGEN INCcall | $0 | – | -248,100 | -100.0% | -1.97% | – | |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -992,900 | -100.0% | -2.83% | – |
| DGX | Exit | QUEST DIAGNOSTIC INC | $0 | – | -792,100 | -100.0% | -3.06% | – |
| LLY | Exit | LILLY ELI & CO | $0 | – | -810,500 | -100.0% | -4.44% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-05-17
Signatures
The EDGAR filing(s) were signed by:
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| NEUROCRINE BIOSCIENCES INC | 15 | Q3 2023 | 4.6% |
| ARVINAS INC | 14 | Q3 2023 | 4.9% |
| ZENTALIS PHARMACEUTICALS INC | 14 | Q3 2023 | 4.8% |
| SYNDAX PHARMACEUTICALS INC | 14 | Q3 2023 | 3.2% |
| IDEAYA BIOSCIENCES INC | 13 | Q3 2023 | 2.5% |
| NATERA INC | 13 | Q3 2023 | 1.9% |
| ALPINE IMMUNE SCIENCES INC | 13 | Q3 2023 | 0.5% |
| ABBVIE INC | 12 | Q2 2023 | 9.7% |
| HORIZON THERAPEUTICS PUB LTD | 12 | Q3 2022 | 3.4% |
| AVANTOR INC | 11 | Q1 2023 | 6.0% |
View Avidity Partners Management LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Adicet Bio, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ALPINE IMMUNE SCIENCES, INC. | February 14, 2023 | 1,888,887 | 4.0% |
| ESSA Pharma Inc. | February 14, 2023 | 1,855,400 | 4.2% |
| Gritstone bio, Inc. | February 14, 2023 | 2,859,971 | 3.3% |
| IVERIC bio, Inc. | February 14, 2023 | 838,407 | 0.6% |
| ONCOSEC MEDICAL IncSold out | February 14, 2023 | 0 | 0.0% |
| PhaseBio Pharmaceuticals Inc | February 14, 2023 | 2,040,000 | 4.1% |
| Phathom Pharmaceuticals, Inc. | February 14, 2023 | 1,900,000 | 4.6% |
| Viridian Therapeutics, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Anika Therapeutics, Inc.Sold out | February 14, 2022 | 0 | 0.0% |
View Avidity Partners Management LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-04-09 |
| SC 13G | 2024-03-27 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-13 |
| SC 13G/A | 2024-02-13 |
| SC 13G/A | 2024-02-13 |
View Avidity Partners Management LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.