$602 Million is the total value of Opaleye Management Inc.'s 48 reported holdings in Q2 2021. The portfolio turnover from Q1 2021 to Q2 2021 was 34.5% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| OCUL | OCULAR THERAPEUTIX INC | $91,886,000 | -13.6% | 6,480,000 | 0.0% | 15.26% | -2.3% | |
| CMRX | Buy | CHIMERIX INC | $37,040,000 | -14.4% | 4,630,000 | +3.1% | 6.15% | -3.2% |
| CLDX | CELLDEX THERAPEUTICS INC | $32,938,000 | +62.3% | 985,000 | 0.0% | 5.47% | +83.6% | |
| BBIO | Sell | BRIDGEBIO PHARMA INC | $31,525,000 | -12.3% | 517,150 | -11.4% | 5.24% | -0.9% |
| CDXS | Sell | CODEXIS INC | $30,478,000 | -4.9% | 1,345,000 | -3.9% | 5.06% | +7.5% |
| ETON | Sell | ETON PHARMACEUTICALS INC | $29,310,000 | -0.9% | 3,692,600 | -8.6% | 4.87% | +12.1% |
| HROW | Buy | HARROW HEALTH INC | $29,171,000 | +41.0% | 3,140,000 | +2.4% | 4.84% | +59.4% |
| TARA | PROTARA THERAPEUTICS INC | $24,920,000 | -38.1% | 2,558,472 | 0.0% | 4.14% | -30.0% | |
| STXS | STEREOTAXIS INC | $24,355,000 | +43.5% | 2,526,500 | 0.0% | 4.04% | +62.2% | |
| TCON | TRACON PHARMACEUTICALS INC | $16,344,000 | -21.1% | 2,518,371 | 0.0% | 2.72% | -10.8% | |
| KNSA | Buy | KINIKSA PHARMACEUTICALS LTD | $16,092,000 | +170.9% | 1,155,200 | +260.0% | 2.67% | +206.5% |
| MGNX | Sell | MACROGENICS INC | $15,529,000 | -26.8% | 578,150 | -13.2% | 2.58% | -17.3% |
| PTGX | Buy | PROTAGONIST THERAPEUTICS INC | $14,820,000 | +92.7% | 330,222 | +11.2% | 2.46% | +117.9% |
| FBIO | FORTRESS BIOTECH INC | $13,834,000 | +1.1% | 3,875,000 | 0.0% | 2.30% | +14.4% | |
| XOMA | Sell | XOMA CORP DEL | $11,682,000 | -34.6% | 343,600 | -21.5% | 1.94% | -26.0% |
| CYTK | CYTOKINETICS INC | $11,478,000 | -14.9% | 580,000 | 0.0% | 1.91% | -3.8% | |
| NLTX | Sell | NEOLEUKIN THERAPEUTICS INC | $10,672,000 | -29.2% | 1,156,200 | -5.6% | 1.77% | -20.0% |
| AFIB | Sell | ACUTUS MEDICAL INC | $10,188,000 | +23.9% | 599,990 | -2.4% | 1.69% | +40.1% |
| KROS | Buy | KEROS THERAPEUTICS INC | $9,980,000 | +3.0% | 235,000 | +49.2% | 1.66% | +16.4% |
| VSTM | VERASTEM INC | $9,463,000 | +64.8% | 2,325,000 | 0.0% | 1.57% | +86.3% | |
| PRQR | Buy | PROQR THERAPEUTICS NV | $9,304,000 | +8.0% | 1,380,400 | +5.9% | 1.54% | +22.1% |
| STRO | Buy | SUTRO BIOPHARMA INC | $9,237,000 | +18.7% | 496,900 | +45.3% | 1.53% | +34.2% |
| ADMS | ADAMAS PHARMACEUTICALS INC | $8,821,000 | +10.0% | 1,670,600 | 0.0% | 1.46% | +24.4% | |
| EPIX | ESSA PHARMA INC | $8,115,000 | -1.7% | 284,050 | 0.0% | 1.35% | +11.2% | |
| PCVX | VAXCYTE INC | $8,054,000 | +14.0% | 357,800 | 0.0% | 1.34% | +28.9% | |
| DCPH | Sell | DECIPHERA PHARMACEUTICALS IN | $7,519,000 | -24.5% | 205,381 | -7.5% | 1.25% | -14.6% |
| LRMR | New | LARIMAR THERAPEUTICS INC | $7,147,000 | – | 727,800 | +100.0% | 1.19% | – |
| TELA | Buy | TELA BIO INC | $7,096,000 | +30.5% | 440,465 | +20.7% | 1.18% | +47.6% |
| MCRB | Sell | SERES THERAPEUTICS INC | $5,963,000 | -39.2% | 250,000 | -16.7% | 0.99% | -31.2% |
| SIOX | SIO GENE THERAPIES INC | $5,258,000 | +0.7% | 2,000,000 | 0.0% | 0.87% | +13.8% | |
| CMLF | New | CM LIFE SCIENCES INC | $5,237,000 | – | 373,828 | +100.0% | 0.87% | – |
| CERC | Sell | CERECOR INC | $5,126,000 | -34.7% | 1,567,494 | -39.7% | 0.85% | -26.2% |
| MEIP | Buy | MEI PHARMA INC | $4,460,000 | -16.4% | 1,565,000 | +0.6% | 0.74% | -5.5% |
| AVEO | Sell | AVEO BIOSCIENCES INC | $4,264,000 | -30.2% | 647,000 | -22.5% | 0.71% | -21.2% |
| FMTX | New | FORMA THERAPEUTICS HOLDINGS INC | $4,256,000 | – | 171,000 | +100.0% | 0.71% | – |
| LUMO | Buy | LUMOS PHARMA INC | $3,820,000 | -13.4% | 382,000 | +1.4% | 0.63% | -2.2% |
| OPTN | Buy | OPTINOSE INC | $3,815,000 | +25.2% | 1,226,600 | +48.5% | 0.63% | +41.5% |
| KZR | Sell | KEZAR LIFE SCIENCES INC | $3,789,000 | -10.6% | 697,800 | -1.9% | 0.63% | +1.0% |
| CRNX | Buy | CRINETICS PHARMACEUTICALS INC | $3,779,000 | +31.5% | 200,500 | +6.6% | 0.63% | +48.8% |
| Buy | APTOSE BIOSCIENCES INC | $3,254,000 | -37.5% | 980,000 | +12.4% | 0.54% | -29.4% | |
| SRRA | Buy | SIERRA ONCOLOGY INC | $3,222,000 | +23.7% | 165,500 | +9.5% | 0.54% | +40.1% |
| CRDF | Sell | CARDIFF ONCOLOGY INC | $3,079,000 | -42.3% | 463,000 | -19.6% | 0.51% | -34.7% |
| VIRX | Buy | VIRACTA THERAPEUTICS INC | $2,917,000 | +204.5% | 257,189 | +148.3% | 0.48% | +244.0% |
| PHVS | New | PHARVARIS NV | $1,487,000 | – | 79,837 | +100.0% | 0.25% | – |
| LPTX | Buy | LEAP THERAPEUTICS INC | $886,000 | +20.2% | 540,000 | +39.1% | 0.15% | +36.1% |
| CFRX | Sell | CONTRAFECT CORP | $255,000 | -78.2% | 57,900 | -76.3% | 0.04% | -75.6% |
| CDTX | New | CIDARA THERAPEUTICS INC | $148,000 | – | 73,351 | +100.0% | 0.02% | – |
| BLRX | BIOLINERX LTDsponsored ads | $47,000 | 0.0% | 16,667 | 0.0% | 0.01% | +14.3% | |
| MGTA | Exit | MAGENTA THERAPEUTICS INC | $0 | – | -88,400 | -100.0% | -0.15% | – |
| AYLA | Exit | AYALA PHARMECEUTICALS INC | $0 | – | -108,551 | -100.0% | -0.17% | – |
| ARPO | Exit | AERPIO PHARMACEUTICALS INC | $0 | – | -1,000,000 | -100.0% | -0.19% | – |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -156,500 | -100.0% | -0.24% | – |
| BHVN | Exit | BIOHAVEN PHARMACEUTICAL HLDG | $0 | – | -25,000 | -100.0% | -0.25% | – |
| EDAP | Exit | EDAP TMS SAsponsored adr | $0 | – | -341,300 | -100.0% | -0.42% | – |
| CAPA | Exit | HIGHCAPE CAPITAL ACQUISITION CORP | $0 | – | -241,300 | -100.0% | -0.42% | – |
| FGEN | Exit | FIBROGEN INC | $0 | – | -147,000 | -100.0% | -0.75% | – |
| MYOV | Exit | MYOVANT SCIENCES LTD | $0 | – | -249,800 | -100.0% | -0.76% | – |
| CBIO | Exit | CATALYST BIOSCIENCES INC | $0 | – | -1,250,000 | -100.0% | -0.92% | – |
| SMTI | Exit | SANARA MEDTECH INC | $0 | – | -225,000 | -100.0% | -1.03% | – |
| IMVT | Exit | IMMUNOVANT INC | $0 | – | -467,000 | -100.0% | -1.10% | – |
| CKPT | Exit | CHECKPOINT THERAPEUTICS INC | $0 | – | -2,925,963 | -100.0% | -1.35% | – |
| GMTX | Exit | GEMINI THERAPEUTICS INC | $0 | – | -810,500 | -100.0% | -1.61% | – |
| AUTL | Exit | AUTOLUS THERAPEUTICS PLCsponsored ads | $0 | – | -2,112,918 | -100.0% | -1.78% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-08-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| CODEXIS INC | 39 | Q3 2023 | 10.9% |
| CHIMERIX INC | 31 | Q3 2022 | 16.4% |
| XOMA CORP DEL | 27 | Q3 2023 | 3.6% |
| FIBROGEN INC | 26 | Q1 2021 | 6.8% |
| BIOLINERX LTD (Does not reflect a reverse stock split effectuated after June 30, 2019) | 26 | Q1 2020 | 2.4% |
| OCULAR THERAPEUTIX INC | 24 | Q3 2023 | 17.6% |
| AXOGEN INC | 20 | Q4 2019 | 18.7% |
| ETON PHARMACEUTICALS INC | 20 | Q3 2023 | 5.6% |
| AMARIN CORP PLC | 20 | Q4 2020 | 6.6% |
| IMPRIMIS PHARMACEUTICALS INC | 19 | Q1 2020 | 5.9% |
View Opaleye Management Inc.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| CHIMERIX INCSold out | February 13, 2023 | 0 | 0.0% |
| Larimar Therapeutics, Inc. | January 23, 2023 | 1,560,000 | 3.6% |
| TELA Bio, Inc. | June 10, 2022 | 1,557,500 | 10.7% |
| Gemini Therapeutics, Inc. /DESold out | February 01, 2022 | 0 | 0.0% |
| Adamas Pharmaceuticals IncSold out | January 26, 2022 | 0 | 0.0% |
| AVENUE THERAPEUTICS, INC. | February 12, 2021 | 9 | 11.0% |
| Cardiff Oncology, Inc. | February 12, 2021 | 9 | 11.0% |
| EDAP TMS SA | February 12, 2021 | 9 | 11.0% |
| Fortress Biotech, Inc. | February 12, 2021 | 9 | 11.0% |
| Gemini Therapeutics, Inc. /DE | February 12, 2021 | 9 | 11.0% |
View Opaleye Management Inc.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 4 | 2024-04-25 |
| 4 | 2024-04-24 |
| 4 | 2024-04-19 |
| SC 13G/A | 2024-04-09 |
| SC 13G | 2024-04-08 |
| 4 | 2024-03-28 |
| 4 | 2024-03-22 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View Opaleye Management Inc.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.