$3.2 Billion is the total value of EcoR1 Capital, LLC's 87 reported holdings in Q1 2022. The portfolio turnover from Q4 2021 to Q1 2022 was 115.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PRTA | Buy | PROTHENA CORP PLC | $423,637,000 | -24.0% | 11,584,280 | +2.7% | 13.25% | -25.4% |
| APLS | Buy | APELLIS PHARMACEUTICALS INC | $263,370,000 | +38.1% | 5,183,431 | +28.5% | 8.24% | +35.5% |
| GLPG | Buy | GALAPAGOS NVspon adr | $198,193,000 | +61.6% | 3,195,624 | +43.7% | 6.20% | +58.6% |
| SRPT | New | SAREPTA THERAPEUTICS INC | $161,680,000 | – | 2,069,634 | +100.0% | 5.06% | – |
| ACAD | Buy | ACADIA PHARMACEUTICALS INC | $145,114,000 | +103.1% | 5,991,479 | +95.8% | 4.54% | +99.4% |
| XNCR | Buy | XENCOR INC | $132,566,000 | -32.7% | 4,968,756 | +1.3% | 4.15% | -33.9% |
| KURA | Buy | KURA ONCOLOGY INC | $106,745,000 | +104.7% | 6,638,371 | +78.2% | 3.34% | +100.9% |
| ARVN | Buy | ARVINAS INC | $101,214,000 | +845.7% | 1,503,929 | +1054.2% | 3.17% | +828.4% |
| ZLAB | New | ZAI LAB LTDadr | $97,777,000 | – | 2,223,212 | +100.0% | 3.06% | – |
| ALEC | Buy | ALECTOR INC | $81,773,000 | -20.7% | 5,738,448 | +14.9% | 2.56% | -22.2% |
| RLAY | Buy | RELAY THERAPEUTICS INC | $68,583,000 | +25.5% | 2,291,441 | +28.8% | 2.14% | +23.2% |
| RETA | New | REATA PHARMACEUTICALS INCcl a | $64,721,000 | – | 1,975,611 | +100.0% | 2.02% | – |
| Buy | 2SEVENTY BIO INC | $59,641,000 | +21.4% | 3,495,943 | +82.4% | 1.87% | +19.2% | |
| CERE | New | CEREVEL THERAPEUTICS HLDNG I | $57,636,000 | – | 1,646,260 | +100.0% | 1.80% | – |
| AVIR | Buy | ATEA PHARMACEUTICALS INC | $45,779,000 | -4.8% | 6,340,639 | +17.9% | 1.43% | -6.5% |
| MRTX | New | MIRATI THERAPEUTICS INC | $41,161,000 | – | 500,622 | +100.0% | 1.29% | – |
| ARGX | New | ARGENX SEsponsored adr | $39,414,000 | – | 125,000 | +100.0% | 1.23% | – |
| DSGN | Buy | DESIGN THERAPEUTICS INC | $38,299,000 | -16.9% | 2,371,445 | +10.1% | 1.20% | -18.4% |
| RVMD | New | REVOLUTION MEDICINES INC | $32,502,000 | – | 1,274,097 | +100.0% | 1.02% | – |
| PCVX | Buy | VAXCYTE INC | $31,509,000 | +6265.5% | 1,304,741 | +6172.8% | 0.99% | +6062.5% |
| BCYC | New | BICYCLE THERAPEUTICS PLCsponsored ads | $24,022,000 | – | 547,453 | +100.0% | 0.75% | – |
| EWTX | Buy | EDGEWISE THERAPEUTICS INC | $22,890,000 | +17.1% | 2,359,808 | +84.5% | 0.72% | +14.9% |
| EXEL | New | EXELIXIS INC | $21,567,000 | – | 951,333 | +100.0% | 0.68% | – |
| JANX | Buy | JANUX THERAPEUTICS INC | $20,382,000 | -26.8% | 1,421,319 | +0.7% | 0.64% | -28.2% |
| GERN | New | GERON CORP | $19,429,000 | – | 14,285,714 | +100.0% | 0.61% | – |
| OVID | Buy | OVID THERAPEUTICS INC | $19,209,000 | -1.6% | 6,117,400 | +0.6% | 0.60% | -3.4% |
| SWTX | New | SPRINGWORKS THERAPEUTICS INC | $18,393,000 | – | 325,881 | +100.0% | 0.58% | – |
| CRNX | Buy | CRINETICS PHARMACEUTICALS IN | $17,345,000 | +3.4% | 790,209 | +33.9% | 0.54% | +1.7% |
| ARQT | New | ARCUTIS BIOTHERAPEUTICS INC | $17,247,000 | – | 895,503 | +100.0% | 0.54% | – |
| SURF | New | SURFACE ONCOLOGY INC | $13,680,000 | – | 4,653,000 | +100.0% | 0.43% | – |
| PMVP | Buy | PMV PHARMACEUTICALS INC | $13,529,000 | +1071.3% | 649,786 | +1199.6% | 0.42% | +1043.2% |
| HOOK | New | HOOKIPA PHARMA INC | $11,400,000 | – | 5,000,000 | +100.0% | 0.36% | – |
| KDNY | New | CHINOOK THERAPEUTICS INC | $11,288,000 | – | 690,000 | +100.0% | 0.35% | – |
| ALGS | Buy | ALIGOS THERAPEUTICS INC | $8,489,000 | +685.3% | 3,948,360 | +4236.8% | 0.27% | +682.4% |
| NGM | New | NGM BIOPHARMACEUTICALS INC | $8,252,000 | – | 541,108 | +100.0% | 0.26% | – |
| IGMS | New | IGM BIOSCIENCES INC | $7,981,000 | – | 298,597 | +100.0% | 0.25% | – |
| ZNTL | New | ZENTALIS PHARMACEUTICALS INC | $5,317,000 | – | 115,236 | +100.0% | 0.17% | – |
| GRPH | Buy | GRAPHITE BIO INC | $5,224,000 | -39.0% | 1,024,279 | +48.7% | 0.16% | -40.3% |
| GRCL | New | GRACELL BIOTECHNOLOGIES INCsponsored ads | $3,634,000 | – | 1,559,710 | +100.0% | 0.11% | – |
| MRSN | New | MERSANA THERAPEUTICS INC | $1,303,000 | – | 326,578 | +100.0% | 0.04% | – |
| BCEL | New | ATRECA INC | $1,137,000 | – | 358,780 | +100.0% | 0.04% | – |
| EUCRW | New | EUCRATES BIOMEDICAL ACQU CORcall | $656,000 | – | 66,666 | +100.0% | 0.02% | – |
| RDUS | New | RADIUS HEALTH INC | $309,000 | – | 35,000 | +100.0% | 0.01% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-05-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-05-03 |
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.