$1.35 Billion is the total value of EcoR1 Capital, LLC's 49 reported holdings in Q2 2020. The portfolio turnover from Q1 2020 to Q2 2020 was 86.3% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XNCR | Buy | XENCOR INC | $147,280,000 | +97.0% | 4,547,072 | +81.8% | 10.88% | +39.3% |
| PRTA | PROTHENA CORP PLC | $98,603,000 | -2.2% | 9,426,640 | 0.0% | 7.28% | -30.9% | |
| ORIC | New | ORIC PHARMACEUTICALS INC | $89,122,000 | – | 2,642,218 | +100.0% | 6.58% | – |
| MORF | Buy | MORPHIC HLDG INC | $76,767,000 | +85.2% | 2,837,973 | +0.5% | 5.67% | +30.9% |
| KURA | Buy | KURA ONCOLOGY INC | $75,119,000 | +115.0% | 4,608,529 | +31.2% | 5.55% | +52.0% |
| ASMB | Buy | ASSEMBLY BIOSCIENCES INC | $73,547,000 | +91.4% | 3,153,797 | +21.7% | 5.43% | +35.3% |
| DRNA | Sell | DICERNA PHARMACEUTICALS INC | $69,139,000 | +12.5% | 2,721,993 | -18.7% | 5.11% | -20.5% |
| ANAB | Buy | ANAPTYSBIO INC | $68,696,000 | +60.1% | 3,075,014 | +1.3% | 5.07% | +13.2% |
| RNA | New | AVIDITY BIOSCIENCES INC | $59,458,000 | – | 2,103,950 | +100.0% | 4.39% | – |
| NLTX | Sell | NEOLEUKIN THERAPEUTICS INC | $58,709,000 | +39.7% | 3,536,684 | -4.2% | 4.34% | -1.3% |
| RCUS | Buy | ARCUS BIOSCIENCES INC | $44,779,000 | +1004.6% | 1,810,000 | +519.7% | 3.31% | +680.0% |
| AKUS | New | AKOUOS INC | $44,460,000 | – | 1,975,984 | +100.0% | 3.28% | – |
| GERN | New | GERON CORP | $41,923,000 | – | 19,230,769 | +100.0% | 3.10% | – |
| MRTX | MIRATI THERAPEUTICS INC | $40,856,000 | +48.5% | 357,849 | 0.0% | 3.02% | +5.0% | |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $40,605,000 | +146.2% | 519,119 | +39.8% | 3.00% | +74.1% |
| SURF | Buy | SURFACE ONCOLOGY INC | $33,022,000 | +1285.7% | 5,033,861 | +295.0% | 2.44% | +879.5% |
| BCEL | Buy | ATRECA INC | $31,690,000 | +73.1% | 1,489,185 | +34.6% | 2.34% | +22.4% |
| AMTI | New | APPLIED MOLECULAR TRANS INC | $28,911,000 | – | 1,150,000 | +100.0% | 2.14% | – |
| CNST | New | CONSTELLATION PHARMCETICLS I | $25,178,000 | – | 837,885 | +100.0% | 1.86% | – |
| FATE | Sell | FATE THERAPEUTICS INC | $21,267,000 | -59.1% | 619,855 | -73.5% | 1.57% | -71.1% |
| DNLI | Buy | DENALI THERAPEUTICS INC | $17,738,000 | +45.1% | 733,561 | +5.1% | 1.31% | +2.6% |
| BMYRT | Buy | BRISTOL-MYERS SQUIBB COright 99/99/9999 | $16,999,000 | +99.0% | 4,748,300 | +111.2% | 1.26% | +40.5% |
| CYCN | CYCLERION THERAPEUTICS INC | $16,207,000 | +123.0% | 2,742,276 | 0.0% | 1.20% | +57.7% | |
| FULC | New | FULCRUM THERAPEUTICS INC | $16,138,000 | – | 882,353 | +100.0% | 1.19% | – |
| CRNX | Buy | CRINETICS PHARMACEUTICALS IN | $15,064,000 | +192.8% | 859,802 | +145.7% | 1.11% | +107.1% |
| STRO | New | SUTRO BIOPHARMA INC | $14,189,000 | – | 1,828,492 | +100.0% | 1.05% | – |
| CNST | New | CONSTELLATION PHARMCETICLS Icall | $12,020,000 | – | 400,000 | +100.0% | 0.89% | – |
| RLMD | New | RELMADA THERAPEUTICS INC | $8,950,000 | – | 200,000 | +100.0% | 0.66% | – |
| KROS | New | KEROS THERAPEUTICS INC | $8,260,000 | – | 220,216 | +100.0% | 0.61% | – |
| GLYC | New | GLYCOMIMETICS INC | $7,103,000 | – | 1,889,000 | +100.0% | 0.52% | – |
| ACAD | Sell | ACADIA PHARMACEUTICALS INC | $6,563,000 | -52.0% | 135,413 | -58.2% | 0.48% | -66.1% |
| EVLO | New | EVELO BIOSCIENCES INC | $6,125,000 | – | 1,250,000 | +100.0% | 0.45% | – |
| PRVL | Sell | PREVAIL THERAPEUTICS INC | $5,472,000 | -80.0% | 367,218 | -83.7% | 0.40% | -85.9% |
| IRWD | New | IRONWOOD PHARMACEUTICALS INCcall | $5,160,000 | – | 500,000 | +100.0% | 0.38% | – |
| XCUR | Sell | EXICURE INC | $4,083,000 | -2.9% | 1,673,301 | -41.1% | 0.30% | -31.2% |
| SVRA | SAVARA INC | $3,567,000 | +17.5% | 1,432,664 | 0.0% | 0.26% | -17.0% | |
| MGTA | New | MAGENTA THERAPEUTICS INC | $3,380,000 | – | 450,000 | +100.0% | 0.25% | – |
| LSACU | LIFESCI ACQUISITION CORPunit 03/31/2025 | $3,300,000 | +10.0% | 300,000 | 0.0% | 0.24% | -22.0% | |
| ACRS | Sell | ACLARIS THERAPEUTICS INC | $2,481,000 | +14.3% | 1,531,312 | -26.6% | 0.18% | -19.4% |
| RPRX | New | ROYALTY PHARMA PLC | $2,428,000 | – | 50,000 | +100.0% | 0.18% | – |
| FPRX | Buy | FIVE PRIME THERAPEUTICS INC | $2,318,000 | +299.0% | 379,945 | +48.4% | 0.17% | +180.3% |
| CRVS | CORVUS PHARMACEUTICALS INC | $2,006,000 | +28.9% | 737,612 | 0.0% | 0.15% | -9.2% | |
| RPTX | New | REPARE THERAPEUTICS INC | $1,551,000 | – | 50,000 | +100.0% | 0.12% | – |
| ICPT | New | INTERCEPT PHARMACEUTICALS INcall | $1,212,000 | – | 25,300 | +100.0% | 0.09% | – |
| MGTX | MEIRAGTX HLDGS PLC | $1,187,000 | -6.8% | 94,819 | 0.0% | 0.09% | -33.8% | |
| XOMA | XOMA CORP DEL | $1,004,000 | -2.9% | 50,809 | 0.0% | 0.07% | -31.5% | |
| KLDO | New | KALEIDO BIOSCIENCES INC | $233,000 | – | 31,374 | +100.0% | 0.02% | – |
| EQ | New | EQUILLIUM INC | $174,000 | – | 59,014 | +100.0% | 0.01% | – |
| PLRX | New | PLIANT THERAPEUTICS INC | $42,000 | – | 1,300 | +100.0% | 0.00% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -1,101 | -100.0% | -0.00% | – |
| EXEL | Exit | EXELIXIS INC | $0 | – | -6,269 | -100.0% | -0.01% | – |
| PIRS | Exit | PIERIS PHARMACEUTICALS INC | $0 | – | -264,166 | -100.0% | -0.06% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -13,946 | -100.0% | -0.08% | – |
| RGLS | Exit | REGULUS THERAPEUTICS INC | $0 | – | -1,886,812 | -100.0% | -0.09% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -291,997 | -100.0% | -0.12% | – | |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -30,510 | -100.0% | -0.14% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -41,407 | -100.0% | -0.15% | – |
| CHMA | Exit | CHIASMA INC | $0 | – | -1,512,627 | -100.0% | -0.58% | – |
| VSTM | Exit | VERASTEM INC | $0 | – | -3,255,813 | -100.0% | -0.90% | – |
| ZIOP | Exit | ZIOPHARM ONCOLOGY INC | $0 | – | -3,750,000 | -100.0% | -0.96% | – |
| VIR | Exit | VIR BIOTECHNOLOGY INC | $0 | – | -270,418 | -100.0% | -0.97% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -208,609 | -100.0% | -1.03% | – |
| SELB | Exit | SELECTA BIOSCIENCES INC | $0 | – | -4,597,701 | -100.0% | -1.16% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -1,249,611 | -100.0% | -1.21% | – |
| GMAB | Exit | GENMAB A/Ssponsored ads | $0 | – | -653,981 | -100.0% | -1.45% | – |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -2,308,079 | -100.0% | -1.54% | – |
| MRUS | Exit | MERUS N V | $0 | – | -1,715,962 | -100.0% | -2.17% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INC | $0 | – | -2,536,156 | -100.0% | -2.24% | – |
| IPHA | Exit | INNATE PHARMA S Asponsored ads | $0 | – | -4,465,668 | -100.0% | -3.12% | – |
| FGEN | Exit | FIBROGEN INC | $0 | – | -882,138 | -100.0% | -3.20% | – |
| IRWD | Exit | IRONWOOD PHARMACEUTICALS INC | $0 | – | -4,393,236 | -100.0% | -4.63% | – |
| ARVN | Exit | ARVINAS INC | $0 | – | -1,528,031 | -100.0% | -6.43% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2020-08-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.