$1.08 Billion is the total value of EcoR1 Capital, LLC's 41 reported holdings in Q1 2019. The portfolio turnover from Q4 2018 to Q1 2019 was 56.6% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ARGX | ARGENX SEsponsored adr | $103,004,000 | +29.9% | 825,087 | 0.0% | 9.50% | +19.7% | |
| KURA | KURA ONCOLOGY INC | $87,541,000 | +18.2% | 5,276,753 | 0.0% | 8.07% | +8.9% | |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $73,300,000 | +167.0% | 1,000,000 | +54.5% | 6.76% | +146.0% |
| CRSP | Buy | CRISPR THERAPEUTICS AG | $67,092,000 | +1024.4% | 1,878,277 | +799.3% | 6.18% | +936.0% |
| XNCR | Buy | XENCOR INC | $63,966,000 | +78.9% | 2,059,429 | +108.2% | 5.90% | +64.8% |
| ONCE | Sell | SPARK THERAPEUTICS INC | $60,243,000 | +35.4% | 529,000 | -53.5% | 5.55% | +24.7% |
| IRWD | Sell | IRONWOOD PHARMACEUTICALS INC | $59,494,000 | +6.7% | 4,397,168 | -18.3% | 5.48% | -1.7% |
| New | FIBROGEN INCput | $54,350,000 | – | 1,000,000 | +100.0% | 5.01% | – | |
| DRNA | DICERNA PHARMACEUTICALS INC | $48,585,000 | +37.0% | 3,316,407 | 0.0% | 4.48% | +26.3% | |
| ASND | Sell | ASCENDIS PHARMA A Ssponsored adr | $42,468,000 | -0.3% | 360,819 | -46.9% | 3.92% | -8.1% |
| ASCENDIS PHARMA A Sput | $42,372,000 | +87.9% | 360,000 | 0.0% | 3.91% | +73.1% | ||
| RARE | New | ULTRAGENYX PHARMACEUTICAL INC | $34,534,000 | – | 497,899 | +100.0% | 3.18% | – |
| New | MIRATI THERAPEUTICS INCcall | $25,574,000 | – | 348,900 | +100.0% | 2.36% | – | |
| MYOK | Buy | MYOKARDIA INC | $24,881,000 | +117.3% | 478,574 | +104.2% | 2.29% | +100.2% |
| Sell | FIBROGEN INCcall | $23,957,000 | -38.4% | 440,800 | -47.6% | 2.21% | -43.3% | |
| ASMB | Sell | ASSEMBLY BIOSCIENCES INC | $22,714,000 | -58.2% | 1,153,599 | -52.0% | 2.09% | -61.5% |
| EIGR | EIGER BIOPHARMACEUTICALS INC | $22,307,000 | +37.6% | 1,595,643 | 0.0% | 2.06% | +26.8% | |
| MGTA | Sell | MAGENTA THERAPEUTICS INC | $21,045,000 | +167.6% | 1,277,787 | -7.4% | 1.94% | +146.5% |
| GOSS | New | GOSSAMER BIO INC | $16,731,000 | – | 772,096 | +100.0% | 1.54% | – |
| CHMA | Buy | CHIASMA INC | $15,828,000 | +1240.2% | 3,043,827 | +701.5% | 1.46% | +1136.4% |
| KZR | Sell | KEZAR LIFE SCIENCES INC | $15,194,000 | -39.3% | 856,471 | -19.2% | 1.40% | -44.0% |
| Sell | IRONWOOD PHARMACUTICALS INCcall | $14,675,000 | +20.8% | 1,084,600 | -7.5% | 1.35% | +11.4% | |
| HARP | New | HARPOON THERAPEUTICS INC | $12,656,000 | – | 1,336,423 | +100.0% | 1.17% | – |
| RCUS | Sell | ARCUS BIOSCIENCES INC | $12,367,000 | -6.1% | 990,146 | -19.1% | 1.14% | -13.6% |
| MRSN | New | MERSANA THERAPEUTICS INC | $12,098,000 | – | 2,300,000 | +100.0% | 1.12% | – |
| RUBY | Buy | RUBIUS THERAPEUTICS INC | $11,697,000 | +22.9% | 646,228 | +9.1% | 1.08% | +13.1% |
| RYTM | RHYTHM PHARMACEUTICALS INC | $10,987,000 | +2.0% | 400,838 | 0.0% | 1.01% | -6.0% | |
| SURF | Buy | SURFACE ONCOLOGY INC | $10,797,000 | +12.6% | 2,263,488 | +0.1% | 1.00% | +3.8% |
| FGEN | Sell | FIBROGEN INC | $9,152,000 | -87.0% | 168,382 | -89.0% | 0.84% | -88.0% |
| PRTA | Sell | PROTHENA CORP PLC | $8,813,000 | +2.1% | 726,519 | -13.3% | 0.81% | -6.0% |
| RCKT | ROCKET PHARMACEUTICALS INC | $7,893,000 | +18.4% | 450,000 | 0.0% | 0.73% | +9.1% | |
| ABUS | Sell | ARBUTUS BIOPHARMA CORP | $7,779,000 | -38.1% | 2,172,883 | -33.8% | 0.72% | -43.0% |
| ADRO | New | ADURO BIOTECH INC | $7,719,000 | – | 1,939,390 | +100.0% | 0.71% | – |
| UBX | Sell | UNITY BIOTECHNOLOGY INC | $7,353,000 | -53.2% | 906,614 | -6.3% | 0.68% | -56.9% |
| SRRK | Sell | SCHOLAR ROCK HOLDING CORP | $6,364,000 | -81.2% | 338,668 | -77.0% | 0.59% | -82.7% |
| AQXP | AQUINOX PHARMACEUTICALS INC | $6,107,000 | +24.8% | 2,265,880 | 0.0% | 0.56% | +14.9% | |
| CRIS | CURIS INC | $5,935,000 | +188.5% | 2,982,208 | 0.0% | 0.55% | +165.5% | |
| ZLAB | Sell | ZAI LAB LTDsponsored adr | $2,317,000 | -82.5% | 78,519 | -86.2% | 0.21% | -83.8% |
| VCEL | New | VERICEL CORP | $2,294,000 | – | 131,001 | +100.0% | 0.21% | – |
| SNNAQ | New | SIENNA BIOPHARMACEUTICALS INC | $1,856,000 | – | 800,000 | +100.0% | 0.17% | – |
| ARVN | ARVINAS INC | $738,000 | +14.8% | 50,000 | 0.0% | 0.07% | +6.2% | |
| PRQR | Exit | PROQR THERAPEUTICS N V | $0 | – | -11,022 | -100.0% | -0.02% | – |
| CNST | Exit | CONSTELLATION PHARMACEUTICALS INC | $0 | – | -79,194 | -100.0% | -0.03% | – |
| AFMD | Exit | AFFIMED N V | $0 | – | -158,221 | -100.0% | -0.05% | – |
| ONTX | Exit | ONCONOVA THERAPEUTICS INC | $0 | – | -423,441 | -100.0% | -0.09% | – |
| CRVS | Exit | CORVUS PHARMACEUTICALS INC | $0 | – | -295,420 | -100.0% | -0.11% | – |
| DVAX | Exit | DYNAVAX TECHNOLOGIES CORP | $0 | – | -140,118 | -100.0% | -0.13% | – |
| CORT | Exit | CORCEPT THERAPEUTICS INC | $0 | – | -166,005 | -100.0% | -0.22% | – |
| FPRX | Exit | FIVE PRIME THERAPEUTICS INC | $0 | – | -326,775 | -100.0% | -0.30% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -613,728 | -100.0% | -0.45% | – |
| PTLA | Exit | PORTOLA PHARMACEUTICALS INC | $0 | – | -247,858 | -100.0% | -0.48% | – |
| IMDZ | Exit | IMMUNE DESIGN CORP | $0 | – | -5,603,191 | -100.0% | -0.73% | – |
| ARRY | Exit | ARRAY BIOPHARMA INC | $0 | – | -644,002 | -100.0% | -0.92% | – |
| WVE | Exit | WAVE LIFE SCIENCES LTD | $0 | – | -233,933 | -100.0% | -0.98% | – |
| Exit | NEKTAR THERAPEUTICScall | $0 | – | -316,700 | -100.0% | -1.04% | – | |
| Exit | CELGENE CORPcall | $0 | – | -195,000 | -100.0% | -1.25% | – | |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -1,185,831 | -100.0% | -1.36% | – |
| Exit | ASCENDIS PHARMA A Scall | $0 | – | -250,400 | -100.0% | -1.57% | – | |
| Exit | GILEAD SCIENCES INCcall | $0 | – | -285,100 | -100.0% | -1.78% | – | |
| AKCA | Exit | AKCEA THERAPEUTICS INC | $0 | – | -639,743 | -100.0% | -1.93% | – |
| SLDB | Exit | SOLID BIOSCIENCES INC | $0 | – | -867,246 | -100.0% | -2.33% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -725,326 | -100.0% | -3.92% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2019-05-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| KURA ONCOLOGY ORD | 32 | Q3 2023 | 10.5% |
| XENCOR ORD | 25 | Q3 2023 | 12.6% |
| ASSEMBLY BIOSCIENCES ORD | 23 | Q3 2020 | 19.0% |
| FIBROGEN ORD | 22 | Q1 2020 | 12.4% |
| PROTHENA ORD | 20 | Q3 2023 | 28.0% |
| IRONWOOD PHARMA CL A ORD | 20 | Q1 2020 | 13.9% |
| GALAPAGOS NV SPON ADR | 19 | Q3 2023 | 12.0% |
| MORPHIC HOLDING ORD | 18 | Q3 2023 | 8.5% |
| ARCUS BIOSCIENCES ORD | 17 | Q1 2022 | 7.1% |
| ANAPTYSBIO INC | 16 | Q3 2023 | 8.3% |
View EcoR1 Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Mersana Therapeutics, Inc. | July 27, 2023 | 19,364,688 | 16.9% |
| TScan Therapeutics, Inc. | June 05, 2023 | 5,000,000 | 11.7% |
| 2seventy bio, Inc. | February 14, 2023 | 1,143,494 | 3.0% |
| Avidity Biosciences, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Surface Oncology, Inc. | February 13, 2023 | 3,924,713 | 6.5% |
| Akouos, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Alector, Inc. | February 10, 2023 | 4,056,548 | 4.9% |
| Arcus Biosciences, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Gritstone bio, Inc.Sold out | February 10, 2023 | 0 | 0.0% |
| Ovid Therapeutics Inc. | February 10, 2023 | 6,117,400 | 8.7% |
View EcoR1 Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-08 |
| 3 | 2024-03-26 |
| SC 13G/A | 2024-03-26 |
| SC 13G | 2024-03-11 |
| SC 13D | 2024-02-22 |
| SC 13G | 2024-02-16 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View EcoR1 Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.