$1.29 Billion is the total value of Casdin Capital, LLC's 46 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 40.5% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $170,397,700 | +25.8% | 1,315,000 | +7.3% | 13.20% | +48.4% |
| BLFS | BIOLIFE SOLUTIONS INC | $137,735,266 | -20.0% | 7,566,292 | 0.0% | 10.67% | -5.6% | |
| EQRX INC | $97,238,066 | -50.3% | 39,527,669 | 0.0% | 7.53% | -41.4% | ||
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $86,742,250 | -33.1% | 365,000 | -43.7% | 6.72% | -21.1% |
| ILMN | ILLUMINA INC | $77,847,000 | +6.0% | 385,000 | 0.0% | 6.03% | +25.0% | |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $64,742,418 | -42.2% | 1,477,800 | -13.1% | 5.02% | -31.8% |
| RVMD | Buy | REVOLUTION MEDICINES INC | $60,145,500 | +20.9% | 2,525,000 | +0.1% | 4.66% | +42.6% |
| Sell | MAXCYTE INC | $51,897,300 | -25.6% | 9,505,000 | -11.5% | 4.02% | -12.3% | |
| RLAY | Sell | RELAY THERAPEUTICS INC | $45,277,881 | -56.8% | 3,030,648 | -35.3% | 3.51% | -49.0% |
| VERV | Sell | VERVE THERAPEUTICS INC | $44,322,549 | -59.4% | 2,290,571 | -27.9% | 3.43% | -52.1% |
| DNLI | Buy | DENALI THERAPEUTICS INC | $36,153,000 | +18.4% | 1,300,000 | +30.7% | 2.80% | +39.6% |
| PLRX | Buy | PLIANT THERAPEUTICS INC | $32,377,750 | +106.6% | 1,675,000 | +123.3% | 2.51% | +143.8% |
| SOMALOGIC INC | $31,636,730 | -13.4% | 12,604,275 | 0.0% | 2.45% | +2.1% | ||
| EXAS | Sell | EXACT SCIENCES CORP | $27,973,150 | -11.0% | 565,000 | -41.6% | 2.17% | +5.0% |
| ABCL | Buy | ABCELLERA BIOLOGICS INC | $22,995,100 | +40.9% | 2,270,000 | +37.6% | 1.78% | +66.2% |
| TWST | Buy | TWIST BIOSCIENCE CORP | $22,500,450 | +74.9% | 945,000 | +158.9% | 1.74% | +106.3% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $21,522,250 | +23.3% | 475,000 | +90.0% | 1.67% | +45.4% |
| FATE | FATE THERAPEUTICS INC | $20,684,500 | -55.0% | 2,050,000 | 0.0% | 1.60% | -46.9% | |
| RNA | New | AVIDITY BIOSCIENCES INC | $18,861,500 | – | 850,000 | +100.0% | 1.46% | – |
| Buy | 2SEVENTY BIO INC | $17,334,500 | +93.8% | 1,850,000 | +200.9% | 1.34% | +128.4% | |
| NVTA | Buy | INVITAE CORP | $16,811,402 | +506.9% | 9,038,388 | +702.8% | 1.30% | +615.9% |
| RXDX | New | PROMETHEUS BIOSCIENCES INC | $16,500,000 | – | 150,000 | +100.0% | 1.28% | – |
| IPSC | CENTURY THERAPEUTICS INC | $16,448,729 | -48.1% | 3,206,380 | 0.0% | 1.27% | -38.8% | |
| Sell | ABSCI CORPORATION | $15,462,846 | -36.0% | 7,363,260 | -4.6% | 1.20% | -24.5% | |
| BEAM | BEAM THERAPEUTICS INC | $14,470,700 | -17.9% | 370,000 | 0.0% | 1.12% | -3.2% | |
| FDMT | New | 4D MOLECULAR THERAPEUTICS IN | $13,992,300 | – | 630,000 | +100.0% | 1.08% | – |
| New | PRIME MEDICINE INC | $13,644,223 | – | 734,350 | +100.0% | 1.06% | – | |
| Buy | TENAYA THERAPEUTICS INC | $12,218,509 | +17.5% | 6,078,860 | +69.5% | 0.95% | +38.7% | |
| MRNA | Buy | MODERNA INC | $10,777,200 | +180.4% | 60,000 | +84.6% | 0.84% | +231.3% |
| NTLA | INTELLIA THERAPEUTICS INC | $10,292,550 | -37.7% | 295,000 | 0.0% | 0.80% | -26.5% | |
| VEEV | New | VEEVA SYS INC | $8,069,000 | – | 50,000 | +100.0% | 0.62% | – |
| ARVN | ARVINAS INC | $6,842,000 | -23.1% | 200,000 | 0.0% | 0.53% | -9.2% | |
| INCY | New | INCYTE CORP | $6,224,800 | – | 77,500 | +100.0% | 0.48% | – |
| MRNA | New | MODERNA INCcall | $5,388,600 | – | 30,000 | +100.0% | 0.42% | – |
| New | DICE THERAPEUTICS INC | $5,148,000 | – | 165,000 | +100.0% | 0.40% | – | |
| MRTX | MIRATI THERAPEUTICS INCcall | $4,531,000 | -35.1% | 100,000 | 0.0% | 0.35% | -23.5% | |
| OPRX | New | OPTIMIZERX CORP | $4,368,000 | – | 260,000 | +100.0% | 0.34% | – |
| SEMA4 HOLDINGS CORP | $4,336,213 | -69.9% | 16,437,500 | 0.0% | 0.34% | -64.5% | ||
| New | DEFINITIVE HEALTHCARE CORP | $3,956,400 | – | 360,000 | +100.0% | 0.31% | – | |
| GLUE | MONTE ROSA THERAPEUTICS INC | $3,887,812 | -6.9% | 510,882 | 0.0% | 0.30% | +9.9% | |
| KROS | New | KEROS THERAPEUTICS INC | $3,121,300 | – | 65,000 | +100.0% | 0.24% | – |
| OMIC | SINGULAR GENOMICS SYSTEMS IN | $2,704,901 | -19.6% | 1,345,722 | 0.0% | 0.21% | -5.0% | |
| WVE | New | WAVE LIFE SCIENCES LTD | $1,400,000 | – | 200,000 | +100.0% | 0.11% | – |
| EXSCIENTIA PLCads | $1,140,087 | -35.1% | 213,900 | 0.0% | 0.09% | -23.5% | ||
| LIANBIOsponsored ads | $338,521 | -17.6% | 206,415 | 0.0% | 0.03% | -3.7% | ||
| KRON | KRONOS BIO INC | $200,619 | -51.7% | 123,839 | 0.0% | 0.02% | -40.7% | |
| MGTA | Exit | MAGENTA THERAPEUTICS INC | $0 | – | -320,000 | -100.0% | -0.03% | – |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -80,000 | -100.0% | -0.15% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -165,000 | -100.0% | -0.30% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| BLUEPRINT MEDICINES CORP | 32 | Q3 2023 | 9.6% |
| ALNYLAM PHARMACEUTICALS INC | 32 | Q3 2023 | 9.9% |
| AGIOS PHARMACEUTICALS INC | 27 | Q2 2022 | 12.1% |
| GLOBAL BLOOD THERAPEUTICS IN | 27 | Q2 2022 | 7.1% |
| FATE THERAPEUTICS INC | 26 | Q3 2023 | 8.3% |
| BIOLIFE SOLUTIONS INC | 22 | Q3 2023 | 14.9% |
| CODEXIS INC | 22 | Q3 2023 | 8.1% |
| SAREPTA THERAPEUTICS INC | 21 | Q3 2023 | 13.6% |
| BLUEBIRD BIO INC | 21 | Q4 2020 | 7.8% |
| ILLUMINA INC | 21 | Q3 2023 | 6.0% |
View Casdin Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Absci Corp | May 08, 2023 | 4,448,260 | 4.8% |
| CODEXIS, INC.Sold out | February 14, 2023 | 0 | 0.0% |
| DermTech, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Invitae Corp | February 14, 2023 | 9,038,388 | 3.7% |
| Magenta Therapeutics, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Tango Therapeutics, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Verve Therapeutics, Inc. | February 14, 2023 | 2,290,571 | 3.7% |
| Tenaya Therapeutics, Inc. | December 07, 2022 | 6,427,200 | 9.9% |
| Fulcrum Therapeutics, Inc. | February 11, 2021 | 1,241,176 | 4.5% |
| Gritstone Oncology, Inc.Sold out | February 11, 2021 | 0 | 0.0% |
View Casdin Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-04-18 |
| SC 13D/A | 2024-04-08 |
| 4 | 2024-03-28 |
| 3 | 2024-03-25 |
| 4 | 2024-03-25 |
| 4 | 2024-03-20 |
| SC 13D/A | 2024-03-20 |
| 4 | 2024-03-06 |
| 4 | 2024-03-06 |
| 13F-HR | 2024-02-14 |
View Casdin Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.