Q3 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SRPT | Sell | SAREPTA THERAPEUTICS INC | $122,472,203 | +5.4% | 1,010,330 | -0.5% | 13.56% | +33.4% |
| BLFS | Buy | BIOLIFE SOLUTIONS INC | $107,441,800 | -37.0% | 7,780,000 | +0.8% | 11.89% | -20.3% |
| Buy | STRUCTURE THERAPEUTICS INCsponsored ads | $61,956,632 | +49.5% | 1,258,166 | +26.2% | 6.86% | +89.3% | |
| RLAY | Buy | RELAY THERAPEUTICS INC | $58,227,257 | -22.7% | 6,923,574 | +15.4% | 6.44% | -2.1% |
| VERV | Buy | VERVE THERAPEUTICS INC | $39,179,455 | -11.5% | 2,954,710 | +25.2% | 4.34% | +12.1% |
| NTLA | Sell | INTELLIA THERAPEUTICS INC | $37,250,732 | -28.4% | 1,178,075 | -7.6% | 4.12% | -9.3% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $35,420,000 | -33.4% | 200,000 | -28.6% | 3.92% | -15.7% |
| EXAS | Sell | EXACT SCIENCES CORP | $31,343,679 | -33.2% | 459,450 | -8.1% | 3.47% | -15.5% |
| PLRX | Sell | PLIANT THERAPEUTICS INC | $27,347,053 | -11.2% | 1,577,108 | -7.2% | 3.03% | +12.4% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $21,711,480 | +2423.4% | 498,427 | +1993.0% | 2.40% | +3104.0% |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $18,650,603 | -52.4% | 371,378 | -40.1% | 2.06% | -39.7% |
| Buy | TANGO THERAPEUTICS INC | $14,720,750 | +343.4% | 1,307,349 | +30.7% | 1.63% | +461.7% | |
| FDMT | Sell | 4D MOLECULAR THERAPEUTICS IN | $13,160,414 | -31.9% | 1,033,811 | -3.4% | 1.46% | -13.8% |
| ABCL | Sell | ABCELLERA BIOLOGICS INC | $10,856,593 | -33.3% | 2,360,129 | -6.3% | 1.20% | -15.5% |
| PACB | New | PACIFIC BIOSCIENCES CALIF IN | $8,649,423 | – | 1,035,859 | – | 0.96% | – |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $7,975,000 | -15.4% | 1,250,000 | +47.1% | 0.88% | +7.2% |
| Sell | MAXCYTE INC | $5,896,800 | -72.8% | 1,890,000 | -59.9% | 0.65% | -65.5% | |
| ALNY | New | ALNYLAM PHARMACEUTICALS INCcall | $3,542,000 | – | 20,000 | – | 0.39% | – |
| ILMN | Sell | ILLUMINA INC | $3,432,000 | -88.2% | 25,000 | -83.9% | 0.38% | -85.0% |
| ILMN | New | ILLUMINA INCcall | $3,432,000 | – | 25,000 | – | 0.38% | – |
| Sell | ABSCI CORPORATION | $1,284,703 | -38.2% | 973,260 | -28.9% | 0.14% | -22.0% | |
| CDXS | New | CODEXIS INC | $567,000 | – | 300,000 | – | 0.06% | – |
| OMIC | Sell | SINGULAR GENOMICS SYSTEMS IN | $504,400 | -54.8% | 1,323,885 | -1.6% | 0.06% | -42.9% |
| Exit | SCILEX HOLDING CO | $0 | – | -23,512 | – | -0.01% | – | |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -90,000 | – | -0.37% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -77,500 | – | -0.42% | – |
| TWST | Exit | TWIST BIOSCIENCE CORP | $0 | – | -450,000 | – | -0.80% | – |
| CTLT | Exit | CATALENT INC | $0 | – | -720,000 | – | -2.73% | – |
Q2 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BLFS | New | BIOLIFE SOLUTIONS INC | $170,645,924 | – | 7,721,535 | – | 14.91% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $116,237,800 | – | 1,015,000 | – | 10.16% | – |
| RLAY | New | RELAY THERAPEUTICS INC | $75,342,089 | – | 5,998,574 | – | 6.58% | – |
| New | EQRX INC | $73,521,464 | – | 39,527,669 | – | 6.42% | – | |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $53,183,200 | – | 280,000 | – | 4.65% | – |
| NTLA | New | INTELLIA THERAPEUTICS INC | $51,994,500 | – | 1,275,000 | – | 4.54% | – |
| RVMD | New | REVOLUTION MEDICINES INC | $48,417,500 | – | 1,810,000 | – | 4.23% | – |
| EXAS | New | EXACT SCIENCES CORP | $46,950,000 | – | 500,000 | – | 4.10% | – |
| VERV | New | VERVE THERAPEUTICS INC | $44,260,706 | – | 2,360,571 | – | 3.87% | – |
| New | STRUCTURE THERAPEUTICS INCsponsored ads | $41,445,997 | – | 997,017 | – | 3.62% | – | |
| BPMC | New | BLUEPRINT MEDICINES CORP | $39,184,000 | – | 620,000 | – | 3.42% | – |
| DNLI | New | DENALI THERAPEUTICS INC | $38,363,000 | – | 1,300,000 | – | 3.35% | – |
| New | TENAYA THERAPEUTICS INC | $37,458,683 | – | 6,381,377 | – | 3.27% | – | |
| CTLT | New | CATALENT INC | $31,219,200 | – | 720,000 | – | 2.73% | – |
| PLRX | New | PLIANT THERAPEUTICS INC | $30,804,000 | – | 1,700,000 | – | 2.69% | – |
| New | SOMALOGIC INC | $29,115,875 | – | 12,604,275 | – | 2.54% | – | |
| ILMN | New | ILLUMINA INC | $29,060,950 | – | 155,000 | – | 2.54% | – |
| New | MAXCYTE INC | $21,641,850 | – | 4,715,000 | – | 1.89% | – | |
| New | 2SEVENTY BIO INC | $20,482,000 | – | 2,023,913 | – | 1.79% | – | |
| FDMT | New | 4D MOLECULAR THERAPEUTICS IN | $19,334,900 | – | 1,070,000 | – | 1.69% | – |
| New | GENEDX HOLDINGS CORP | $18,449,246 | – | 3,095,511 | – | 1.61% | – | |
| BEAM | New | BEAM THERAPEUTICS INC | $18,200,100 | – | 570,000 | – | 1.59% | – |
| ABCL | New | ABCELLERA BIOLOGICS INC | $16,279,200 | – | 2,520,000 | – | 1.42% | – |
| IPSC | New | CENTURY THERAPEUTICS INC | $10,132,161 | – | 3,206,380 | – | 0.88% | – |
| FATE | New | FATE THERAPEUTICS INC | $9,758,000 | – | 2,050,000 | – | 0.85% | – |
| RNA | New | AVIDITY BIOSCIENCES INC | $9,426,500 | – | 850,000 | – | 0.82% | – |
| TWST | New | TWIST BIOSCIENCE CORP | $9,207,000 | – | 450,000 | – | 0.80% | – |
| New | PRIME MEDICINE INC | $5,379,114 | – | 367,175 | – | 0.47% | – | |
| INCY | New | INCYTE CORP | $4,824,375 | – | 77,500 | – | 0.42% | – |
| SANA | New | SANA BIOTECHNOLOGY INC | $4,470,000 | – | 750,000 | – | 0.39% | – |
| SAGE | New | SAGE THERAPEUTICS INC | $4,231,800 | – | 90,000 | – | 0.37% | – |
| GLUE | New | MONTE ROSA THERAPEUTICS INC | $3,499,542 | – | 510,882 | – | 0.31% | – |
| New | TANGO THERAPEUTICS INC | $3,320,000 | – | 1,000,000 | – | 0.29% | – | |
| FLDM | New | STANDARD BIOTOOLS INC | $2,316,000 | – | 1,200,000 | – | 0.20% | – |
| New | ABSCI CORPORATION | $2,079,755 | – | 1,368,260 | – | 0.18% | – | |
| New | EXSCIENTIA PLCads | $1,266,288 | – | 213,900 | – | 0.11% | – | |
| OMIC | New | SINGULAR GENOMICS SYSTEMS IN | $1,116,949 | – | 1,345,722 | – | 0.10% | – |
| MRTX | New | MIRATI THERAPEUTICS INC | $860,400 | – | 23,814 | – | 0.08% | – |
| New | LIANBIOsponsored ads | $470,626 | – | 206,415 | – | 0.04% | – | |
| KRON | New | KRONOS BIO INC | $213,003 | – | 123,839 | – | 0.02% | – |
| New | SCILEX HOLDING CO | $130,962 | – | 23,512 | – | 0.01% | – |
Q4 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Exit | LIANBIOsponsored ads | $0 | – | -206,415 | – | -0.03% | – | |
| KRON | Exit | KRONOS BIO INC | $0 | – | -123,839 | – | -0.03% | – |
| MGTA | Exit | MAGENTA THERAPEUTICS INC | $0 | – | -320,000 | – | -0.03% | – |
| Exit | EXSCIENTIA PLCads | $0 | – | -213,900 | – | -0.12% | – | |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -80,000 | – | -0.15% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -1,125,888 | – | -0.18% | – |
| OMIC | Exit | SINGULAR GENOMICS SYSTEMS IN | $0 | – | -1,345,722 | – | -0.22% | – |
| MRNA | Exit | MODERNA INC | $0 | – | -32,500 | – | -0.25% | – |
| GLUE | Exit | MONTE ROSA THERAPEUTICS INC | $0 | – | -510,882 | – | -0.27% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -165,000 | – | -0.30% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INCcall | $0 | – | -100,000 | – | -0.46% | – |
| ARVN | Exit | ARVINAS INC | $0 | – | -200,000 | – | -0.58% | – |
| Exit | 2SEVENTY BIO INC | $0 | – | -614,754 | – | -0.59% | – | |
| Exit | TENAYA THERAPEUTICS INC | $0 | – | -3,586,818 | – | -0.68% | – | |
| TWST | Exit | TWIST BIOSCIENCE CORP | $0 | – | -365,000 | – | -0.84% | – |
| Exit | SEMA4 HOLDINGS CORP | $0 | – | -16,437,500 | – | -0.95% | – | |
| PLRX | Exit | PLIANT THERAPEUTICS INC | $0 | – | -750,000 | – | -1.03% | – |
| ABCL | Exit | ABCELLERA BIOLOGICS INC | $0 | – | -1,650,000 | – | -1.07% | – |
| NTLA | Exit | INTELLIA THERAPEUTICS INC | $0 | – | -295,000 | – | -1.08% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -250,000 | – | -1.15% | – |
| BEAM | Exit | BEAM THERAPEUTICS INC | $0 | – | -370,000 | – | -1.16% | – |
| Exit | ABSCI CORPORATION | $0 | – | -7,718,593 | – | -1.59% | – | |
| DNLI | Exit | DENALI THERAPEUTICS INC | $0 | – | -995,000 | – | -2.01% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -967,000 | – | -2.06% | – |
| IPSC | Exit | CENTURY THERAPEUTICS INC | $0 | – | -3,206,380 | – | -2.08% | – |
| Exit | SOMALOGIC INC | $0 | – | -12,604,275 | – | -2.40% | – | |
| FATE | Exit | FATE THERAPEUTICS INC | $0 | – | -2,050,000 | – | -3.02% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -2,522,300 | – | -3.27% | – |
| Exit | MAXCYTE INC | $0 | – | -10,735,786 | – | -4.58% | – | |
| ILMN | Exit | ILLUMINA INC | $0 | – | -385,000 | – | -4.82% | – |
| RLAY | Exit | RELAY THERAPEUTICS INC | $0 | – | -4,683,432 | – | -6.88% | – |
| VERV | Exit | VERVE THERAPEUTICS INC | $0 | – | -3,178,167 | – | -7.17% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -1,700,000 | – | -7.36% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -648,000 | – | -8.52% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -1,225,000 | – | -8.90% | – |
| BLFS | Exit | BIOLIFE SOLUTIONS INC | $0 | – | -7,566,292 | – | -11.31% | – |
| Exit | EQRX INC | $0 | – | -39,527,669 | – | -12.85% | – |
Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $135,412,000 | +177.9% | 1,225,000 | +88.5% | 8.90% | +115.9% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $129,704,000 | +10.5% | 648,000 | -19.5% | 8.52% | -14.2% |
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $112,013,000 | +92.8% | 1,700,000 | +47.8% | 7.36% | +49.8% |
| VERV | Buy | VERVE THERAPEUTICS INC | $109,170,000 | +127.7% | 3,178,167 | +1.3% | 7.17% | +76.9% |
| RLAY | Buy | RELAY THERAPEUTICS INC | $104,768,000 | +53.7% | 4,683,432 | +15.1% | 6.88% | +19.4% |
| ILMN | New | ILLUMINA INC | $73,454,000 | – | 385,000 | – | 4.82% | – |
| Sell | MAXCYTE INC | $69,783,000 | +5.6% | 10,735,786 | -23.2% | 4.58% | -18.0% | |
| RVMD | Buy | REVOLUTION MEDICINES INC | $49,740,000 | +7.7% | 2,522,300 | +6.4% | 3.27% | -16.4% |
| FATE | Sell | FATE THERAPEUTICS INC | $45,941,000 | -11.7% | 2,050,000 | -2.4% | 3.02% | -31.4% |
| Buy | SOMALOGIC INC | $36,552,000 | -34.7% | 12,604,275 | +1.7% | 2.40% | -49.3% | |
| EXAS | Buy | EXACT SCIENCES CORP | $31,418,000 | +77.2% | 967,000 | +114.9% | 2.06% | +37.7% |
| DNLI | Sell | DENALI THERAPEUTICS INC | $30,537,000 | -30.8% | 995,000 | -33.7% | 2.01% | -46.3% |
| BEAM | Sell | BEAM THERAPEUTICS INC | $17,627,000 | +21.4% | 370,000 | -1.3% | 1.16% | -5.6% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $17,460,000 | +168.1% | 250,000 | +157.7% | 1.15% | +108.2% |
| NTLA | New | INTELLIA THERAPEUTICS INC | $16,508,000 | – | 295,000 | – | 1.08% | – |
| ABCL | Buy | ABCELLERA BIOLOGICS INC | $16,319,000 | +104.3% | 1,650,000 | +120.0% | 1.07% | +58.8% |
| PLRX | New | PLIANT THERAPEUTICS INC | $15,668,000 | – | 750,000 | – | 1.03% | – |
| TWST | Sell | TWIST BIOSCIENCE CORP | $12,863,000 | -26.4% | 365,000 | -27.0% | 0.84% | -42.8% |
| ARVN | New | ARVINAS INC | $8,898,000 | – | 200,000 | – | 0.58% | – |
| MRTX | New | MIRATI THERAPEUTICS INCcall | $6,984,000 | – | 100,000 | – | 0.46% | – |
| MRNA | New | MODERNA INC | $3,843,000 | – | 32,500 | – | 0.25% | – |
| OMIC | Buy | SINGULAR GENOMICS SYSTEMS IN | $3,364,000 | +1.7% | 1,345,722 | +55.4% | 0.22% | -21.1% |
| NVTA | Buy | INVITAE CORP | $2,770,000 | +9.3% | 1,125,888 | +8.4% | 0.18% | -15.0% |
| CERE | New | CEREVEL THERAPEUTICS HLDNG I | $2,261,000 | – | 80,000 | – | 0.15% | – |
| Sell | EXSCIENTIA PLCads | $1,756,000 | -75.7% | 213,900 | -67.8% | 0.12% | -81.2% | |
| MGTA | Sell | MAGENTA THERAPEUTICS INC | $451,000 | -84.4% | 320,000 | -86.7% | 0.03% | -87.8% |
| Exit | SCIENCE 37 HOLDINGS INC | $0 | – | -225,000 | – | -0.04% | – | |
| ORIC | Exit | ORIC PHARMACEUTICALS INC | $0 | – | -601,515 | – | -0.23% | – |
| FDMT | Exit | 4D MOLECULAR THERAPEUTICS IN | $0 | – | -555,455 | – | -0.33% | – |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -1,000,000 | – | -0.35% | – |
| PMVP | Exit | PMV PHARMACEUTICALS INC | $0 | – | -300,000 | – | -0.36% | – |
| KRTX | Exit | KARUNA THERAPEUTICS INC | $0 | – | -85,000 | – | -0.91% | – |
| GH | Exit | GUARDANT HEALTH INC | $0 | – | -272,500 | – | -0.93% | – |
| Exit | TANGO THERAPEUTICS INC | $0 | – | -3,500,000 | – | -1.34% | – | |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -785,000 | – | -1.47% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -800,000 | – | -2.16% | – |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| New | EQRX INC | $185,385,000 | – | 39,527,669 | – | 15.68% | – | |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $117,409,000 | – | 805,000 | – | 9.93% | – |
| BLFS | New | BIOLIFE SOLUTIONS INC | $104,490,000 | – | 7,566,292 | – | 8.84% | – |
| RLAY | New | RELAY THERAPEUTICS INC | $68,149,000 | – | 4,068,574 | – | 5.76% | – |
| New | MAXCYTE INC | $66,084,000 | – | 13,971,334 | – | 5.59% | – | |
| BPMC | New | BLUEPRINT MEDICINES CORP | $58,087,000 | – | 1,150,000 | – | 4.91% | – |
| New | SOMALOGIC INC | $55,999,000 | – | 12,389,082 | – | 4.74% | – | |
| FATE | New | FATE THERAPEUTICS INC | $52,038,000 | – | 2,100,000 | – | 4.40% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $48,724,000 | – | 650,000 | – | 4.12% | – |
| VERV | New | VERVE THERAPEUTICS INC | $47,951,000 | – | 3,138,167 | – | 4.05% | – |
| RVMD | New | REVOLUTION MEDICINES INC | $46,191,000 | – | 2,370,000 | – | 3.91% | – |
| DNLI | New | DENALI THERAPEUTICS INC | $44,145,000 | – | 1,500,000 | – | 3.73% | – |
| IPSC | New | CENTURY THERAPEUTICS INC | $26,934,000 | – | 3,206,380 | – | 2.28% | – |
| New | ABSCI CORPORATION | $25,626,000 | – | 7,718,593 | – | 2.17% | – | |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $25,560,000 | – | 800,000 | – | 2.16% | – |
| New | SEMA4 HOLDINGS CORP | $20,711,000 | – | 16,437,500 | – | 1.75% | – | |
| New | TENAYA THERAPEUTICS INC | $20,194,000 | – | 3,586,818 | – | 1.71% | – | |
| EXAS | New | EXACT SCIENCES CORP | $17,726,000 | – | 450,000 | – | 1.50% | – |
| TWST | New | TWIST BIOSCIENCE CORP | $17,480,000 | – | 500,000 | – | 1.48% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $17,403,000 | – | 785,000 | – | 1.47% | – |
| New | TANGO THERAPEUTICS INC | $15,855,000 | – | 3,500,000 | – | 1.34% | – | |
| BEAM | New | BEAM THERAPEUTICS INC | $14,516,000 | – | 375,000 | – | 1.23% | – |
| GH | New | GUARDANT HEALTH INC | $10,993,000 | – | 272,500 | – | 0.93% | – |
| KRTX | New | KARUNA THERAPEUTICS INC | $10,753,000 | – | 85,000 | – | 0.91% | – |
| New | 2SEVENTY BIO INC | $8,115,000 | – | 614,754 | – | 0.69% | – | |
| ABCL | New | ABCELLERA BIOLOGICS INC | $7,988,000 | – | 750,000 | – | 0.68% | – |
| New | EXSCIENTIA PLCads | $7,230,000 | – | 663,900 | – | 0.61% | – | |
| MRTX | New | MIRATI THERAPEUTICS INC | $6,512,000 | – | 97,000 | – | 0.55% | – |
| GLUE | New | MONTE ROSA THERAPEUTICS INC | $4,940,000 | – | 510,882 | – | 0.42% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $4,448,000 | – | 165,000 | – | 0.38% | – |
| PMVP | New | PMV PHARMACEUTICALS INC | $4,275,000 | – | 300,000 | – | 0.36% | – |
| SGMO | New | SANGAMO THERAPEUTICS INC | $4,140,000 | – | 1,000,000 | – | 0.35% | – |
| FDMT | New | 4D MOLECULAR THERAPEUTICS IN | $3,877,000 | – | 555,455 | – | 0.33% | – |
| OMIC | New | SINGULAR GENOMICS SYSTEMS IN | $3,307,000 | – | 865,722 | – | 0.28% | – |
| MGTA | New | MAGENTA THERAPEUTICS INC | $2,898,000 | – | 2,415,000 | – | 0.24% | – |
| ORIC | New | ORIC PHARMACEUTICALS INC | $2,695,000 | – | 601,515 | – | 0.23% | – |
| NVTA | New | INVITAE CORP | $2,534,000 | – | 1,038,388 | – | 0.21% | – |
| New | LIANBIOsponsored ads | $446,000 | – | 206,415 | – | 0.04% | – | |
| New | SCIENCE 37 HOLDINGS INC | $452,000 | – | 225,000 | – | 0.04% | – | |
| KRON | New | KRONOS BIO INC | $451,000 | – | 123,839 | – | 0.04% | – |
Q4 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SANA | Exit | SANA BIOTECHNOLOGY INC | $0 | – | -60,000 | – | -0.03% | – |
| NAUT | Exit | NAUTILUS BIOTECHNOLOGY INC | $0 | – | -225,000 | – | -0.03% | – |
| FHTX | Exit | FOGHORN THERAPEUTICS INC | $0 | – | -215,000 | – | -0.08% | – |
| STOK | Exit | STOKE THERAPEUTICS INC | $0 | – | -120,000 | – | -0.08% | – |
| BLI | Exit | BERKELEY LTS INC | $0 | – | -200,000 | – | -0.10% | – |
| SEER | Exit | SEER INC | $0 | – | -150,000 | – | -0.13% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCads | $0 | – | -2,575,000 | – | -0.15% | – |
| TKNO | Exit | ALPHA TEKNOVA INC | $0 | – | -300,000 | – | -0.19% | – |
| DBTX | Exit | DECIBEL THERAPEUTICS INC | $0 | – | -1,170,048 | – | -0.22% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INCcall | $0 | – | -50,000 | – | -0.23% | – |
| KRON | Exit | KRONOS BIO INC | $0 | – | -583,436 | – | -0.30% | – |
| ORIC | Exit | ORIC PHARMACEUTICALS INC | $0 | – | -601,515 | – | -0.31% | – |
| RXRX | Exit | RECURSION PHARMACEUTICALS INcl a | $0 | – | -548,156 | – | -0.31% | – |
| MASS | Exit | 908 DEVICES INC | $0 | – | -406,502 | – | -0.33% | – |
| ME | Exit | 23ANDME HOLDING CO | $0 | – | -1,841,457 | – | -0.42% | – |
| ZLAB | Exit | ZAI LAB LTDadr | $0 | – | -190,000 | – | -0.50% | – |
| GLUE | Exit | MONTE ROSA THERAPEUTICS INC | $0 | – | -960,883 | – | -0.53% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -1,200,000 | – | -0.57% | – |
| MGTA | Exit | MAGENTA THERAPEUTICS INC | $0 | – | -3,901,589 | – | -0.71% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -266,430 | – | -0.74% | – |
| FDMT | Exit | 4D MOLECULAR THERAPEUTICS IN | $0 | – | -1,115,455 | – | -0.75% | – |
| OMIC | Exit | SINGULAR GENOMICS SYSTEMS IN | $0 | – | -2,692,870 | – | -0.75% | – |
| GBIO | Exit | GENERATION BIO CO | $0 | – | -1,324,275 | – | -0.83% | – |
| ALEC | Exit | ALECTOR INC | $0 | – | -1,650,000 | – | -0.94% | – |
| Exit | SEMA4 HOLDINGS CORP | $0 | – | -5,000,000 | – | -0.94% | – | |
| ADPT | Exit | ADAPTIVE BIOTECHNOLOGIES COR | $0 | – | -1,440,000 | – | -1.22% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -1,925,000 | – | -1.22% | – |
| ALLO | Exit | ALLOGENE THERAPEUTICS INC | $0 | – | -2,100,000 | – | -1.34% | – |
| BGNE | Exit | BEIGENE LTDsponsored adr | $0 | – | -150,000 | – | -1.36% | – |
| Exit | DERMTECH INC | $0 | – | -1,745,000 | – | -1.40% | – | |
| Exit | TANGO THERAPEUTICS INC | $0 | – | -5,487,910 | – | -1.77% | – | |
| BEAM | Exit | BEAM THERAPEUTICS INC | $0 | – | -818,820 | – | -1.77% | – |
| Exit | TENAYA THERAPEUTICS INC | $0 | – | -3,586,818 | – | -1.84% | – | |
| CDNA | Exit | CAREDX INC | $0 | – | -1,193,335 | – | -1.88% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -2,800,000 | – | -1.92% | – |
| IPSC | Exit | CENTURY THERAPEUTICS INC | $0 | – | -3,206,380 | – | -2.01% | – |
| Exit | GINKGO BIOWORKS HOLDINGS INC | $0 | – | -7,202,808 | – | -2.08% | – | |
| DNLI | Exit | DENALI THERAPEUTICS INC | $0 | – | -1,700,000 | – | -2.14% | – |
| Exit | ABSCI CORPORATION | $0 | – | -7,718,593 | – | -2.23% | – | |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -2,165,000 | – | -2.49% | – |
| CDXS | Exit | CODEXIS INC | $0 | – | -4,330,000 | – | -2.51% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -1,100,000 | – | -2.53% | – |
| TWST | Exit | TWIST BIOSCIENCE CORP | $0 | – | -1,000,000 | – | -2.66% | – |
| RLAY | Exit | RELAY THERAPEUTICS INC | $0 | – | -3,668,574 | – | -2.88% | – |
| VERV | Exit | VERVE THERAPEUTICS INC | $0 | – | -3,038,167 | – | -3.55% | – |
| Exit | SOMALOGIC INC | $0 | – | -12,389,082 | – | -3.82% | – | |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -1,550,000 | – | -3.97% | – |
| Exit | MAXCYTE INC | $0 | – | -13,971,334 | – | -4.25% | – | |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -1,000,000 | – | -4.70% | – |
| FATE | Exit | FATE THERAPEUTICS INC | $0 | – | -3,400,000 | – | -5.02% | – |
| PACB | Exit | PACIFIC BIOSCIENCES CALIF IN | $0 | – | -7,990,652 | – | -5.08% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -2,360,186 | – | -5.61% | – |
| BLFS | Exit | BIOLIFE SOLUTIONS INC | $0 | – | -7,566,292 | – | -7.97% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -12,203,669 | – | -8.64% | – |
Q3 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BLFS | Buy | BIOLIFE SOLUTIONS INC | $320,205,000 | -3.3% | 7,566,292 | +1.7% | 7.97% | -5.2% |
| PACB | Buy | PACIFIC BIOSCIENCES CALIF IN | $204,161,000 | +16.8% | 7,990,652 | +59.8% | 5.08% | +14.5% |
| New | MAXCYTE INC | $170,590,000 | – | 13,971,334 | – | 4.25% | – | |
| New | SOMALOGIC INC | $153,501,000 | – | 12,389,082 | – | 3.82% | – | |
| RLAY | Buy | RELAY THERAPEUTICS INC | $115,670,000 | -6.3% | 3,668,574 | +8.7% | 2.88% | -8.2% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $101,728,000 | +47.9% | 1,100,000 | +24.3% | 2.53% | +45.0% |
| New | ABSCI CORPORATION | $89,767,000 | – | 7,718,593 | – | 2.23% | – | |
| DNLI | Buy | DENALI THERAPEUTICS INC | $85,765,000 | -32.1% | 1,700,000 | +5.6% | 2.14% | -33.4% |
| New | GINKGO BIOWORKS HOLDINGS INC | $83,481,000 | – | 7,202,808 | – | 2.08% | – | |
| RVMD | Buy | REVOLUTION MEDICINES INC | $77,028,000 | +5.3% | 2,800,000 | +21.5% | 1.92% | +3.2% |
| New | TENAYA THERAPEUTICS INC | $74,068,000 | – | 3,586,818 | – | 1.84% | – | |
| New | TANGO THERAPEUTICS INC | $70,959,000 | – | 5,487,910 | – | 1.77% | – | |
| ALLO | Buy | ALLOGENE THERAPEUTICS INC | $53,970,000 | +68.9% | 2,100,000 | +71.4% | 1.34% | +65.6% |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS IN | $49,049,000 | +6.9% | 1,925,000 | +46.9% | 1.22% | +4.8% |
| New | SEMA4 HOLDINGS CORP | $37,950,000 | – | 5,000,000 | – | 0.94% | – | |
| GBIO | Sell | GENERATION BIO CO | $33,200,000 | -23.4% | 1,324,275 | -17.8% | 0.83% | -24.9% |
| FDMT | Sell | 4D MOLECULAR THERAPEUTICS IN | $30,084,000 | +12.0% | 1,115,455 | -0.0% | 0.75% | +9.8% |
| MGTA | Buy | MAGENTA THERAPEUTICS INC | $28,404,000 | -13.2% | 3,901,589 | +16.6% | 0.71% | -14.9% |
| ME | Sell | 23ANDME HOLDING CO | $16,684,000 | -47.9% | 1,841,457 | -32.8% | 0.42% | -49.0% |
| VRTX | New | VERTEX PHARMACEUTICALS INCcall | $9,070,000 | – | 50,000 | – | 0.23% | – |
| DBTX | Sell | DECIBEL THERAPEUTICS INC | $9,021,000 | -10.5% | 1,170,048 | -0.1% | 0.22% | -12.1% |
| ORTX | Sell | ORCHARD THERAPEUTICS PLCads | $5,923,000 | -58.0% | 2,575,000 | -19.9% | 0.15% | -58.9% |
| FHTX | Sell | FOGHORN THERAPEUTICS INC | $2,995,000 | +29.8% | 215,000 | -0.6% | 0.08% | +27.1% |
| NAUT | Sell | NAUTILUS BIOTECHNOLOGY INC | $1,382,000 | -72.6% | 225,000 | -55.0% | 0.03% | -73.4% |
| ZY | Exit | ZYMERGEN INC | $0 | – | -30,000 | – | -0.03% | – |
| TPTX | Exit | TURNING POINT THERAPEUTICS I | $0 | – | -75,000 | – | -0.15% | – |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -550,000 | – | -0.17% | – |
| CLOV | Exit | CLOVER HEALTH INVESTMENTS CO | $0 | – | -726,511 | – | -0.25% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -1,154,476 | – | -0.31% | – |
| NEO | Exit | NEOGENOMICS INC | $0 | – | -488,889 | – | -0.56% | – |
| CNST | Exit | CONSTELLATION PHARMCETICLS I | $0 | – | -1,341,000 | – | -1.15% | – |
| AMRS | Exit | AMYRIS INC | $0 | – | -3,000,000 | – | -1.25% | – |
Q2 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NVTA | New | INVITAE CORP | $411,630,000 | – | 12,203,669 | – | 10.45% | – |
| BLFS | New | BIOLIFE SOLUTIONS INC | $331,159,000 | – | 7,440,107 | – | 8.41% | – |
| FATE | New | FATE THERAPEUTICS INC | $295,086,000 | – | 3,400,000 | – | 7.49% | – |
| EXAS | New | EXACT SCIENCES CORP | $293,395,000 | – | 2,360,186 | – | 7.45% | – |
| VERV | New | VERVE THERAPEUTICS INC | $183,050,000 | – | 3,038,167 | – | 4.65% | – |
| PACB | New | PACIFIC BIOSCIENCES CALIF IN | $174,850,000 | – | 5,000,000 | – | 4.44% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $169,520,000 | – | 1,000,000 | – | 4.30% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $136,338,000 | – | 1,550,000 | – | 3.46% | – |
| TWST | New | TWIST BIOSCIENCE CORP | $133,250,000 | – | 1,000,000 | – | 3.38% | – |
| DNLI | New | DENALI THERAPEUTICS INC | $126,288,000 | – | 1,610,000 | – | 3.21% | – |
| RLAY | New | RELAY THERAPEUTICS INC | $123,493,000 | – | 3,375,058 | – | 3.14% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $119,313,000 | – | 2,165,000 | – | 3.03% | – |
| CDNA | New | CAREDX INC | $109,214,000 | – | 1,193,335 | – | 2.77% | – |
| BEAM | New | BEAM THERAPEUTICS INC | $105,390,000 | – | 818,820 | – | 2.68% | – |
| CDXS | New | CODEXIS INC | $98,118,000 | – | 4,330,000 | – | 2.49% | – |
| IPSC | New | CENTURY THERAPEUTICS INC | $94,075,000 | – | 3,206,380 | – | 2.39% | – |
| OMIC | New | SINGULAR GENOMICS SYSTEMS IN | $74,000,000 | – | 2,692,870 | – | 1.88% | – |
| RVMD | New | REVOLUTION MEDICINES INC | $73,161,000 | – | 2,305,000 | – | 1.86% | – |
| New | DERMTECH INC | $72,540,000 | – | 1,745,000 | – | 1.84% | – | |
| SRPT | New | SAREPTA THERAPEUTICS INC | $68,800,000 | – | 885,000 | – | 1.75% | – |
| ADPT | New | ADAPTIVE BIOTECHNOLOGIES COR | $58,838,000 | – | 1,440,000 | – | 1.49% | – |
| BGNE | New | BEIGENE LTDsponsored adr | $51,479,000 | – | 150,000 | – | 1.31% | – |
| AMRS | New | AMYRIS INC | $49,110,000 | – | 3,000,000 | – | 1.25% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $45,876,000 | – | 1,310,000 | – | 1.16% | – |
| CNST | New | CONSTELLATION PHARMCETICLS I | $45,326,000 | – | 1,341,000 | – | 1.15% | – |
| GBIO | New | GENERATION BIO CO | $43,342,000 | – | 1,611,214 | – | 1.10% | – |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $43,132,000 | – | 266,430 | – | 1.10% | – |
| ALEC | New | ALECTOR INC | $34,370,000 | – | 1,650,000 | – | 0.87% | – |
| ZLAB | New | ZAI LAB LTDadr | $33,628,000 | – | 190,000 | – | 0.85% | – |
| MGTA | New | MAGENTA THERAPEUTICS INC | $32,724,000 | – | 3,346,034 | – | 0.83% | – |
| ME | New | 23ANDME HOLDING CO | $32,048,000 | – | 2,741,457 | – | 0.81% | – |
| ALLO | New | ALLOGENE THERAPEUTICS INC | $31,948,000 | – | 1,225,000 | – | 0.81% | – |
| FDMT | New | 4D MOLECULAR THERAPEUTICS IN | $26,863,000 | – | 1,115,555 | – | 0.68% | – |
| NEO | New | NEOGENOMICS INC | $22,083,000 | – | 488,889 | – | 0.56% | – |
| GLUE | New | MONTE ROSA THERAPEUTICS INC | $21,812,000 | – | 960,883 | – | 0.55% | – |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $20,604,000 | – | 1,200,000 | – | 0.52% | – |
| RXRX | New | RECURSION PHARMACEUTICALS INcl a | $20,008,000 | – | 548,156 | – | 0.51% | – |
| MASS | New | 908 DEVICES INC | $15,752,000 | – | 406,502 | – | 0.40% | – |
| ORTX | New | ORCHARD THERAPEUTICS PLCads | $14,116,000 | – | 3,215,434 | – | 0.36% | – |
| KRON | New | KRONOS BIO INC | $13,973,000 | – | 583,436 | – | 0.36% | – |
| FULC | New | FULCRUM THERAPEUTICS INC | $12,099,000 | – | 1,154,476 | – | 0.31% | – |
| ORIC | New | ORIC PHARMACEUTICALS INC | $10,641,000 | – | 601,515 | – | 0.27% | – |
| DBTX | New | DECIBEL THERAPEUTICS INC | $10,074,000 | – | 1,171,421 | – | 0.26% | – |
| CLOV | New | CLOVER HEALTH INVESTMENTS CO | $9,677,000 | – | 726,511 | – | 0.25% | – |
| BLI | New | BERKELEY LTS INC | $8,962,000 | – | 200,000 | – | 0.23% | – |
| TKNO | New | ALPHA TEKNOVA INC | $7,119,000 | – | 300,000 | – | 0.18% | – |
| SGMO | New | SANGAMO THERAPEUTICS INC | $6,584,000 | – | 550,000 | – | 0.17% | – |
| TPTX | New | TURNING POINT THERAPEUTICS I | $5,852,000 | – | 75,000 | – | 0.15% | – |
| NAUT | New | NAUTILUS BIOTECHNOLOGY INC | $5,050,000 | – | 500,000 | – | 0.13% | – |
| SEER | New | SEER INC | $4,917,000 | – | 150,000 | – | 0.12% | – |
| STOK | New | STOKE THERAPEUTICS INC | $4,039,000 | – | 120,000 | – | 0.10% | – |
| FHTX | New | FOGHORN THERAPEUTICS INC | $2,307,000 | – | 216,216 | – | 0.06% | – |
| SANA | New | SANA BIOTECHNOLOGY INC | $1,180,000 | – | 60,000 | – | 0.03% | – |
| ZY | New | ZYMERGEN INC | $1,200,000 | – | 30,000 | – | 0.03% | – |
Q4 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| DCPH | Exit | DECIPHERA PHARMACEUTICALS IN | $0 | – | -65,000 | – | -0.15% | – |
| STOK | Exit | STOKE THERAPEUTICS INC | $0 | – | -120,000 | – | -0.18% | – |
| LEGN | Exit | LEGEND BIOTECH CORPsponsored ads | $0 | – | -139,661 | – | -0.19% | – |
| ORIC | Exit | ORIC PHARMACEUTICALS INC | $0 | – | -251,515 | – | -0.28% | – |
| TPTX | Exit | TURNING POINT THERAPEUTICS I | $0 | – | -75,000 | – | -0.29% | – |
| DYN | Exit | DYNE THERAPEUTICS INC | $0 | – | -370,000 | – | -0.33% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCads | $0 | – | -1,870,000 | – | -0.34% | – |
| BDTX | Exit | BLACK DIAMOND THERAPEUTICS I | $0 | – | -289,395 | – | -0.39% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -30,000 | – | -0.42% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -290,000 | – | -0.43% | – |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -1,080,000 | – | -0.46% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -1,441,176 | – | -0.51% | – |
| BMYRT | Exit | BRISTOL-MYERS SQUIBB COright 99/99/9999 | $0 | – | -6,250,000 | – | -0.63% | – |
| BLI | Exit | BERKELEY LTS INC | $0 | – | -200,000 | – | -0.68% | – |
| ZLAB | Exit | ZAI LAB LTDadr | $0 | – | -190,000 | – | -0.71% | – |
| Exit | DERMTECH INC | $0 | – | -1,428,572 | – | -0.76% | – | |
| ALEC | Exit | ALECTOR INC | $0 | – | -1,650,000 | – | -0.78% | – |
| TSHA | Exit | TAYSHA GENE THERAPIES INC | $0 | – | -820,440 | – | -0.82% | – |
| CNST | Exit | CONSTELLATION PHARMCETICLS I | $0 | – | -980,000 | – | -0.89% | – |
| AMRS | Exit | AMYRIS INC | $0 | – | -7,390,000 | – | -0.97% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -395,000 | – | -0.98% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -266,430 | – | -1.00% | – |
| MGTA | Exit | MAGENTA THERAPEUTICS INC | $0 | – | -3,346,034 | – | -1.02% | – |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -2,750,000 | – | -1.27% | – |
| ADPT | Exit | ADAPTIVE BIOTECHNOLOGIES COR | $0 | – | -713,125 | – | -1.55% | – |
| ALLO | Exit | ALLOGENE THERAPEUTICS INC | $0 | – | -945,000 | – | -1.60% | – |
| BGNE | Exit | BEIGENE LTDsponsored adr | $0 | – | -150,000 | – | -1.92% | – |
| PACB | Exit | PACIFIC BIOSCIENCES CALIF IN | $0 | – | -4,500,000 | – | -1.99% | – |
| CDNA | Exit | CAREDX INC | $0 | – | -1,193,335 | – | -2.03% | – |
| CDXS | Exit | CODEXIS INC | $0 | – | -3,985,000 | – | -2.10% | – |
| DNLI | Exit | DENALI THERAPEUTICS INC | $0 | – | -1,310,000 | – | -2.10% | – |
| BNR | Exit | BURNING ROCK BIOTECH LTDsponsored ads | $0 | – | -1,922,150 | – | -2.16% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -915,000 | – | -2.21% | – |
| GBIO | Exit | GENERATION BIO CO | $0 | – | -1,611,214 | – | -2.23% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -1,634,535 | – | -2.55% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -1,750,000 | – | -2.74% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -530,000 | – | -3.33% | – |
| TWST | Exit | TWIST BIOSCIENCE CORP | $0 | – | -1,000,000 | – | -3.40% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -620,000 | – | -4.04% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -870,000 | – | -5.31% | – |
| FATE | Exit | FATE THERAPEUTICS INC | $0 | – | -3,050,000 | – | -5.46% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -1,550,000 | – | -6.43% | – |
| RLAY | Exit | RELAY THERAPEUTICS INC | $0 | – | -3,808,894 | – | -7.26% | – |
| BLFS | Exit | BIOLIFE SOLUTIONS INC | $0 | – | -5,840,107 | – | -7.57% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -9,033,943 | – | -17.54% | – |
Q3 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BLFS | Buy | BIOLIFE SOLUTIONS INC | $169,013,000 | +113.2% | 5,840,107 | +20.4% | 7.57% | +61.3% |
| RLAY | New | RELAY THERAPEUTICS INC | $162,221,000 | – | 3,808,894 | – | 7.26% | – |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $90,272,000 | +10.8% | 620,000 | +12.7% | 4.04% | -16.2% |
| AGIO | Buy | AGIOS PHARMACEUTICALS INC | $61,250,000 | +7.0% | 1,750,000 | +63.6% | 2.74% | -19.0% |
| RVMD | Buy | REVOLUTION MEDICINES INC | $56,882,000 | +35.0% | 1,634,535 | +22.5% | 2.55% | +2.2% |
| BLUE | Sell | BLUEBIRD BIO INC | $49,364,000 | -26.8% | 915,000 | -17.2% | 2.21% | -44.6% |
| BNR | Buy | BURNING ROCK BIOTECH LTDsponsored ads | $48,208,000 | +3.1% | 1,922,150 | +11.1% | 2.16% | -22.0% |
| CDXS | Sell | CODEXIS INC | $46,784,000 | -12.5% | 3,985,000 | -15.1% | 2.10% | -33.8% |
| PACB | New | PACIFIC BIOSCIENCES CALIF IN | $44,415,000 | – | 4,500,000 | – | 1.99% | – |
| ALLO | Buy | ALLOGENE THERAPEUTICS INC | $35,636,000 | +33.2% | 945,000 | +51.2% | 1.60% | +0.8% |
| ADVM | Buy | ADVERUM BIOTECHNOLOGIES INC | $28,325,000 | -27.3% | 2,750,000 | +47.5% | 1.27% | -45.0% |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS IN | $21,780,000 | +15.0% | 395,000 | +31.7% | 0.98% | -13.0% |
| AMRS | Buy | AMYRIS INC | $21,579,000 | -5.5% | 7,390,000 | +38.1% | 0.97% | -28.6% |
| TSHA | New | TAYSHA GENE THERAPIES INC | $18,378,000 | – | 820,440 | – | 0.82% | – |
| ALEC | Buy | ALECTOR INC | $17,383,000 | -33.9% | 1,650,000 | +53.3% | 0.78% | -50.0% |
| BLI | New | BERKELEY LTS INC | $15,272,000 | – | 200,000 | – | 0.68% | – |
| BMYRT | Buy | BRISTOL-MYERS SQUIBB COright 99/99/9999 | $14,063,000 | +33.2% | 6,250,000 | +111.9% | 0.63% | +0.8% |
| SGMO | Sell | SANGAMO THERAPEUTICS INC | $10,206,000 | -21.7% | 1,080,000 | -25.8% | 0.46% | -40.8% |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $9,547,000 | – | 290,000 | – | 0.43% | – |
| ORTX | Buy | ORCHARD THERAPEUTICS PLCads | $7,686,000 | -22.4% | 1,870,000 | +13.3% | 0.34% | -41.3% |
| DYN | New | DYNE THERAPEUTICS INC | $7,470,000 | – | 370,000 | – | 0.33% | – |
| LEGN | Buy | LEGEND BIOTECH CORPsponsored ads | $4,311,000 | -25.0% | 139,661 | +3.5% | 0.19% | -43.2% |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -130,000 | – | -0.28% | – |
| VYGR | Exit | VOYAGER THERAPEUTICS INC | $0 | – | -750,000 | – | -0.56% | – |
| GRTS | Exit | GRITSTONE ONCOLOGY INC | $0 | – | -1,850,373 | – | -0.73% | – |
Q2 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NVTA | New | INVITAE CORP | $273,638,000 | – | 9,033,943 | – | 16.19% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $120,900,000 | – | 1,550,000 | – | 7.16% | – |
| FATE | New | FATE THERAPEUTICS INC | $104,646,000 | – | 3,050,000 | – | 6.19% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $84,980,000 | – | 530,000 | – | 5.03% | – |
| MYOK | New | MYOKARDIA INC | $84,059,000 | – | 870,000 | – | 4.98% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $81,461,000 | – | 550,000 | – | 4.82% | – |
| BLFS | New | BIOLIFE SOLUTIONS INC | $79,290,000 | – | 4,849,524 | – | 4.69% | – |
| BLUE | New | BLUEBIRD BIO INC | $67,449,000 | – | 1,105,000 | – | 3.99% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $57,224,000 | – | 1,070,000 | – | 3.39% | – |
| CDXS | New | CODEXIS INC | $53,497,000 | – | 4,692,732 | – | 3.17% | – |
| BNR | New | BURNING ROCK BIOTECH LTDsponsored ads | $46,749,000 | – | 1,730,786 | – | 2.77% | – |
| TWST | New | TWIST BIOSCIENCE CORP | $45,300,000 | – | 1,000,000 | – | 2.68% | – |
| CDNA | New | CAREDX INC | $42,280,000 | – | 1,193,335 | – | 2.50% | – |
| RVMD | New | REVOLUTION MEDICINES INC | $42,131,000 | – | 1,334,536 | – | 2.49% | – |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $38,941,000 | – | 1,865,000 | – | 2.30% | – |
| ADPT | New | ADAPTIVE BIOTECHNOLOGIES COR | $34,501,000 | – | 713,125 | – | 2.04% | – |
| GBIO | New | GENERATION BIO CO | $33,835,000 | – | 1,611,214 | – | 2.00% | – |
| DNLI | New | DENALI THERAPEUTICS INC | $31,676,000 | – | 1,310,000 | – | 1.88% | – |
| CNST | New | CONSTELLATION PHARMCETICLS I | $29,449,000 | – | 980,000 | – | 1.74% | – |
| BGNE | New | BEIGENE LTDsponsored adr | $28,260,000 | – | 150,000 | – | 1.67% | – |
| ALLO | New | ALLOGENE THERAPEUTICS INC | $26,763,000 | – | 625,000 | – | 1.58% | – |
| FULC | New | FULCRUM THERAPEUTICS INC | $26,359,000 | – | 1,441,176 | – | 1.56% | – |
| ALEC | New | ALECTOR INC | $26,298,000 | – | 1,076,039 | – | 1.56% | – |
| MGTA | New | MAGENTA THERAPEUTICS INC | $25,129,000 | – | 3,346,034 | – | 1.49% | – |
| AMRS | New | AMYRIS INC | $22,842,000 | – | 5,349,376 | – | 1.35% | – |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $19,580,000 | – | 266,430 | – | 1.16% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $18,939,000 | – | 300,000 | – | 1.12% | – |
| New | DERMTECH INC | $18,900,000 | – | 1,428,572 | – | 1.12% | – | |
| ZLAB | New | ZAI LAB LTDadr | $15,605,000 | – | 190,000 | – | 0.92% | – |
| SGMO | New | SANGAMO THERAPEUTICS INC | $13,037,000 | – | 1,455,000 | – | 0.77% | – |
| GRTS | New | GRITSTONE ONCOLOGY INC | $12,286,000 | – | 1,850,373 | – | 0.73% | – |
| BDTX | New | BLACK DIAMOND THERAPEUTICS I | $12,201,000 | – | 289,395 | – | 0.72% | – |
| ILMN | New | ILLUMINA INC | $11,111,000 | – | 30,000 | – | 0.66% | – |
| BMYRT | New | BRISTOL-MYERS SQUIBB COright | $10,561,000 | – | 2,950,000 | – | 0.62% | – |
| ORTX | New | ORCHARD THERAPEUTICS PLCads | $9,900,000 | – | 1,650,000 | – | 0.59% | – |
| VYGR | New | VOYAGER THERAPEUTICS INC | $9,465,000 | – | 750,000 | – | 0.56% | – |
| ORIC | New | ORIC PHARMACEUTICALS INC | $8,484,000 | – | 251,515 | – | 0.50% | – |
| LEGN | New | LEGEND BIOTECH CORPsponsored ads | $5,746,000 | – | 135,000 | – | 0.34% | – |
| TPTX | New | TURNING POINT THERAPEUTICS I | $4,844,000 | – | 75,000 | – | 0.29% | – |
| ZYME | New | ZYMEWORKS INC | $4,689,000 | – | 130,000 | – | 0.28% | – |
| DCPH | New | DECIPHERA PHARMACEUTICALS IN | $3,882,000 | – | 65,000 | – | 0.23% | – |
| STOK | New | STOKE THERAPEUTICS INC | $2,860,000 | – | 120,000 | – | 0.17% | – |
Q4 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| STOK | Exit | STOKE THERAPEUTICS INC | $0 | – | -130,000 | – | -0.29% | – |
| TPTX | Exit | TURNING POINT THERAPEUTICS I | $0 | – | -75,000 | – | -0.29% | – |
| DCPH | Exit | DECIPHERA PHARMACEUTICALS IN | $0 | – | -100,000 | – | -0.35% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCadr | $0 | – | -310,000 | – | -0.38% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -844,285 | – | -0.58% | – |
| TWST | Exit | TWIST BIOSCIENCE CORP | $0 | – | -300,000 | – | -0.74% | – |
| EDIT | Exit | EDITAS MEDICINE INC | $0 | – | -415,000 | – | -0.98% | – |
| CNST | Exit | CONSTELLATION PHARMCETICLS I | $0 | – | -1,523,960 | – | -1.02% | – |
| DNLI | Exit | DENALI THERAPEUTICS INC | $0 | – | -650,000 | – | -1.03% | – |
| ALEC | Exit | ALECTOR INC | $0 | – | -811,039 | – | -1.21% | – |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -1,455,000 | – | -1.36% | – |
| ADPT | Exit | ADAPTIVE BIOTECHNOLOGIES COR | $0 | – | -463,125 | – | -1.48% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -300,000 | – | -1.51% | – |
| FIXX | Exit | HOMOLOGY MEDICINES INC | $0 | – | -820,000 | – | -1.54% | – |
| GRTS | Exit | GRITSTONE ONCOLOGY INC | $0 | – | -1,770,000 | – | -1.58% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -60,000 | – | -1.89% | – |
| VYGR | Exit | VOYAGER THERAPEUTICS INC | $0 | – | -1,128,075 | – | -2.01% | – |
| GNMK | Exit | GENMARK DIAGNOSTICS INC | $0 | – | -3,365,000 | – | -2.11% | – |
| CDNA | Exit | CAREDX INC | $0 | – | -1,000,000 | – | -2.34% | – |
| BOLD | Exit | AUDENTES THERAPEUTICS INC | $0 | – | -860,000 | – | -2.50% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -935,000 | – | -3.14% | – |
| MGTA | Exit | MAGENTA THERAPEUTICS INC | $0 | – | -3,048,121 | – | -3.24% | – |
| FATE | Exit | FATE THERAPEUTICS INC | $0 | – | -2,550,000 | – | -4.10% | – |
| BLFS | Exit | BIOLIFE SOLUTIONS INC | $0 | – | -2,428,571 | – | -4.18% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -600,000 | – | -4.99% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -400,000 | – | -5.81% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -612,500 | – | -5.82% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -1,115,000 | – | -6.02% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -880,000 | – | -6.86% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -940,000 | – | -7.15% | – |
| CDXS | Exit | CODEXIS INC | $0 | – | -5,073,780 | – | -7.20% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -3,838,388 | – | -7.66% | – |
| ONCE | Exit | SPARK THERAPEUTICS INC | $0 | – | -863,300 | – | -8.66% | – |
Q3 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ONCE | Sell | SPARK THERAPEUTICS INC | $83,722,834,000 | -7.6% | 863,300 | -2.4% | 8.66% | +2.2% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $66,281,600,000 | +30.2% | 880,000 | +162.7% | 6.86% | +43.9% |
| MYOK | Sell | MYOKARDIA INC | $58,147,250,000 | -9.8% | 1,115,000 | -13.2% | 6.02% | -0.2% |
| BLUE | Buy | BLUEBIRD BIO INC | $56,239,750,000 | +18.7% | 612,500 | +64.4% | 5.82% | +31.2% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $48,252,000,000 | +2.3% | 600,000 | -7.7% | 4.99% | +13.1% |
| MGTA | Buy | MAGENTA THERAPEUTICS INC | $31,273,721,000 | -29.4% | 3,048,121 | +1.5% | 3.24% | -21.9% |
| AGIO | Buy | AGIOS PHARMACEUTICALS INC | $30,294,000,000 | +22.7% | 935,000 | +88.9% | 3.14% | +35.7% |
| BOLD | Sell | AUDENTES THERAPEUTICS INC | $24,157,400,000 | -33.9% | 860,000 | -10.9% | 2.50% | -26.9% |
| CDNA | Buy | CAREDX INC | $22,610,000,000 | +214.1% | 1,000,000 | +400.0% | 2.34% | +247.2% |
| FIXX | Buy | HOMOLOGY MEDICINES INC | $14,842,000,000 | +1.8% | 820,000 | +10.1% | 1.54% | +12.5% |
| SGMO | Sell | SANGAMO THERAPEUTICS INC | $13,167,750,000 | -20.1% | 1,455,000 | -4.9% | 1.36% | -11.6% |
| ALEC | Buy | ALECTOR INC | $11,695,182,000 | +14.8% | 811,039 | +47.2% | 1.21% | +26.8% |
| DNLI | Buy | DENALI THERAPEUTICS INC | $9,958,000,000 | +19.9% | 650,000 | +62.5% | 1.03% | +32.7% |
| EDIT | Sell | EDITAS MEDICINE INC | $9,437,100,000 | -20.5% | 415,000 | -13.5% | 0.98% | -12.1% |
| FULC | New | FULCRUM THERAPEUTICS INC | $5,606,052,000 | – | 844,285 | – | 0.58% | – |
| ORTX | Buy | ORCHARD THERAPEUTICS PLCadr | $3,682,800,000 | +163.2% | 310,000 | +210.0% | 0.38% | +190.8% |
| DCPH | New | DECIPHERA PHARMACEUTICALS IN | $3,394,000,000 | – | 100,000 | – | 0.35% | – |
| TPTX | Buy | TURNING POINT THERAPEUTICS I | $2,820,000,000 | +15.5% | 75,000 | +25.0% | 0.29% | +27.5% |
| STOK | Buy | STOKE THERAPEUTICS INC | $2,793,700,000 | +12.7% | 130,000 | +52.9% | 0.29% | +24.6% |
Q2 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ONCE | New | SPARK THERAPEUTICS INC | $90,585,824,000 | – | 884,800 | – | 8.48% | – |
| NVTA | New | INVITAE CORP | $90,202,118,000 | – | 3,838,388 | – | 8.44% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $88,670,200,000 | – | 940,000 | – | 8.30% | – |
| CDXS | New | CODEXIS INC | $86,519,885,000 | – | 5,073,780 | – | 8.10% | – |
| SAGE | New | SAGE THERAPEUTICS INC | $73,236,000,000 | – | 400,000 | – | 6.86% | – |
| MYOK | New | MYOKARDIA INC | $64,429,900,000 | – | 1,285,000 | – | 6.03% | – |
| FATE | New | FATE THERAPEUTICS INC | $51,765,000,000 | – | 2,550,000 | – | 4.84% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $50,903,250,000 | – | 335,000 | – | 4.76% | – |
| BLUE | New | BLUEBIRD BIO INC | $47,382,000,000 | – | 372,500 | – | 4.44% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $47,164,000,000 | – | 650,000 | – | 4.42% | – |
| MGTA | New | MAGENTA THERAPEUTICS INC | $44,296,035,000 | – | 3,003,121 | – | 4.15% | – |
| BLFS | New | BIOLIFE SOLUTIONS INC | $39,408,375,000 | – | 2,428,571 | – | 3.69% | – |
| BOLD | New | AUDENTES THERAPEUTICS INC | $36,534,900,000 | – | 965,000 | – | 3.42% | – |
| VYGR | New | VOYAGER THERAPEUTICS INC | $30,706,202,000 | – | 1,128,075 | – | 2.87% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $24,690,600,000 | – | 495,000 | – | 2.31% | – |
| ILMN | New | ILLUMINA INC | $22,089,000,000 | – | 60,000 | – | 2.07% | – |
| GNMK | New | GENMARK DIAGNOSTICS INC | $21,838,850,000 | – | 3,365,000 | – | 2.04% | – |
| ADPT | New | ADAPTIVE BIOTECHNOLOGIES COR | $20,100,347,000 | – | 463,125 | – | 1.88% | – |
| GRTS | New | GRITSTONE ONCOLOGY INC | $19,717,800,000 | – | 1,770,000 | – | 1.85% | – |
| CNST | New | CONSTELLATION PHARMCETICLS I | $18,714,229,000 | – | 1,523,960 | – | 1.75% | – |
| SGMO | New | SANGAMO THERAPEUTICS INC | $16,478,100,000 | – | 1,530,000 | – | 1.54% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $15,780,000,000 | – | 300,000 | – | 1.48% | – |
| FIXX | New | HOMOLOGY MEDICINES INC | $14,579,650,000 | – | 745,000 | – | 1.36% | – |
| EDIT | New | EDITAS MEDICINE INC | $11,875,200,000 | – | 480,000 | – | 1.11% | – |
| ALEC | New | ALECTOR INC | $10,189,059,000 | – | 551,039 | – | 0.95% | – |
| TWST | New | TWIST BIOSCIENCE CORP | $8,703,000,000 | – | 300,000 | – | 0.82% | – |
| DNLI | New | DENALI THERAPEUTICS INC | $8,304,000,000 | – | 400,000 | – | 0.78% | – |
| CDNA | New | CAREDX INC | $7,198,000,000 | – | 200,000 | – | 0.67% | – |
| STOK | New | STOKE THERAPEUTICS INC | $2,479,450,000 | – | 85,000 | – | 0.23% | – |
| TPTX | New | TURNING POINT THERAPEUTICS I | $2,442,000,000 | – | 60,000 | – | 0.23% | – |
| ORTX | New | ORCHARD THERAPEUTICS PLCadr | $1,399,000,000 | – | 100,000 | – | 0.13% | – |
Q4 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| JNCE | Exit | JOUNCE THERAPEUTICS INC | $0 | – | -375,000 | – | -0.30% | – |
| NTGN | Exit | NEON THERAPEUTICS INC | $0 | – | -338,345 | – | -0.35% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -207,500 | – | -0.47% | – |
| GILD | Exit | GILEAD SCIENCES INCcall | $0 | – | -50,000 | – | -0.47% | – |
| CELG | Exit | CELGENE CORPcall | $0 | – | -50,000 | – | -0.54% | – |
| NEOG | Exit | NEOGEN CORP | $0 | – | -65,000 | – | -0.56% | – |
| CDNA | Exit | CAREDX INC | $0 | – | -200,000 | – | -0.70% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -40,000 | – | -0.78% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -235,000 | – | -0.84% | – |
| FIXX | Exit | HOMOLOGY MEDICINES INC | $0 | – | -350,000 | – | -0.97% | – |
| OSUR | Exit | ORASURE TECHNOLOGIES INC | $0 | – | -525,000 | – | -0.99% | – |
| CNST | Exit | CONSTELLATION PHARMCETICLS I | $0 | – | -1,314,743 | – | -1.08% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -220,000 | – | -1.19% | – |
| GRTS | Exit | GRITSTONE ONCOLOGY INC | $0 | – | -720,586 | – | -1.25% | – |
| BGNE | Exit | BEIGENE LTDsponsored adr | $0 | – | -70,000 | – | -1.46% | – |
| EDIT | Exit | EDITAS MEDICINE INC | $0 | – | -460,000 | – | -1.78% | – |
| EVH | Exit | EVOLENT HEALTH INCcl a | $0 | – | -550,000 | – | -1.90% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -440,000 | – | -2.03% | – |
| VYGR | Exit | VOYAGER THERAPEUTICS INC | $0 | – | -1,135,000 | – | -2.61% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -270,000 | – | -2.87% | – |
| BOLD | Exit | AUDENTES THERAPEUTICS INC | $0 | – | -625,000 | – | -3.01% | – |
| GNMK | Exit | GENMARK DIAGNOSTICS INC | $0 | – | -3,500,000 | – | -3.13% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -71,500 | – | -3.19% | – |
| MGTA | Exit | MAGENTA THERAPEUTICS INC | $0 | – | -2,250,818 | – | -3.29% | – |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -2,000,000 | – | -4.12% | – |
| CDXS | Exit | CODEXIS INC | $0 | – | -2,025,000 | – | -4.22% | – |
| ONCE | Exit | SPARK THERAPEUTICS INC | $0 | – | -675,000 | – | -4.48% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -258,000 | – | -4.58% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -2,400,000 | – | -4.88% | – |
| FATE | Exit | FATE THERAPEUTICS INC | $0 | – | -2,550,000 | – | -5.05% | – |
| BLFS | Exit | BIOLIFE SOLUTIONS INC | $0 | – | -2,428,571 | – | -5.17% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -312,000 | – | -5.36% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -579,776 | – | -5.43% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -805,000 | – | -6.38% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -750,000 | – | -7.12% | – |
| LOXO | Exit | LOXO ONCOLOGY INC | $0 | – | -360,000 | – | -7.48% | – |
Q3 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $58,545,000 | +45.2% | 750,000 | +18.1% | 7.12% | +26.2% |
| MYOK | Buy | MYOKARDIA INC | $52,486,000 | +35.5% | 805,000 | +3.2% | 6.38% | +17.8% |
| AGIO | Buy | AGIOS PHARMACEUTICALS INC | $44,712,000 | +45.5% | 579,776 | +58.9% | 5.43% | +26.5% |
| SAGE | Buy | SAGE THERAPEUTICS INC | $44,070,000 | +12.6% | 312,000 | +24.8% | 5.36% | -2.1% |
| BLFS | Buy | BIOLIFE SOLUTIONS INC | $42,500,000 | +272.5% | 2,428,571 | +142.9% | 5.17% | +223.7% |
| FATE | Sell | FATE THERAPEUTICS INC | $41,540,000 | +40.9% | 2,550,000 | -1.9% | 5.05% | +22.5% |
| NVTA | New | INVITAE CORP | $40,152,000 | – | 2,400,000 | – | 4.88% | – |
| BLUE | Buy | BLUEBIRD BIO INC | $37,668,000 | +20.0% | 258,000 | +29.0% | 4.58% | +4.3% |
| ONCE | Buy | SPARK THERAPEUTICS INC | $36,821,000 | -3.9% | 675,000 | +45.8% | 4.48% | -16.5% |
| SGMO | Buy | SANGAMO THERAPEUTICS INC | $33,900,000 | +70.5% | 2,000,000 | +42.9% | 4.12% | +48.2% |
| MGTA | Buy | MAGENTA THERAPEUTICS INC | $27,032,000 | -1.6% | 2,250,818 | +10.6% | 3.29% | -14.5% |
| GNMK | Buy | GENMARK DIAGNOSTICS INC | $25,725,000 | +18.6% | 3,500,000 | +2.9% | 3.13% | +3.1% |
| BOLD | Buy | AUDENTES THERAPEUTICS INC | $24,744,000 | +43.9% | 625,000 | +38.9% | 3.01% | +25.0% |
| GBT | Sell | GLOBAL BLOOD THERAPEUTICS IN | $16,720,000 | -22.9% | 440,000 | -8.3% | 2.03% | -33.0% |
| EDIT | Buy | EDITAS MEDICINE INC | $14,637,000 | +129.1% | 460,000 | +157.9% | 1.78% | +99.0% |
| GRTS | New | GRITSTONE ONCOLOGY INC | $10,261,000 | – | 720,586 | – | 1.25% | – |
| CNST | New | CONSTELLATION PHARMCETICLS I | $8,848,000 | – | 1,314,743 | – | 1.08% | – |
| OSUR | Sell | ORASURE TECHNOLOGIES INC | $8,111,000 | -23.1% | 525,000 | -18.0% | 0.99% | -33.1% |
| FIXX | Buy | HOMOLOGY MEDICINES INC | $8,001,000 | +241.0% | 350,000 | +204.3% | 0.97% | +196.3% |
| CLVS | Buy | CLOVIS ONCOLOGY INC | $6,902,000 | -31.0% | 235,000 | +6.8% | 0.84% | -40.0% |
| SRPT | New | SAREPTA THERAPEUTICS INC | $6,460,000 | – | 40,000 | – | 0.78% | – |
| CELG | New | CELGENE CORPcall | $4,475,000 | – | 50,000 | – | 0.54% | – |
| GILD | New | GILEAD SCIENCES INCcall | $3,861,000 | – | 50,000 | – | 0.47% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORPcall | $0 | – | -10,000 | – | -0.09% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS INput | $0 | – | -50,000 | – | -0.32% | – |
| ZLAB | Exit | ZAI LAB LTDadr | $0 | – | -135,000 | – | -0.44% | – |
| LOXO | Exit | LOXO ONCOLOGY INCput | $0 | – | -20,000 | – | -0.48% | – |
| FMI | Exit | FOUNDATION MEDICINE INC | $0 | – | -685,000 | – | -13.10% | – |
Q2 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FMI | New | FOUNDATION MEDICINE INC | $93,640,000 | – | 685,000 | – | 13.10% | – |
| LOXO | New | LOXO ONCOLOGY INC | $62,453,000 | – | 360,000 | – | 8.73% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $40,310,000 | – | 635,000 | – | 5.64% | – |
| SAGE | New | SAGE THERAPEUTICS INC | $39,133,000 | – | 250,000 | – | 5.47% | – |
| MYOK | New | MYOKARDIA INC | $38,727,000 | – | 780,000 | – | 5.42% | – |
| ONCE | New | SPARK THERAPEUTICS INC | $38,318,000 | – | 463,000 | – | 5.36% | – |
| BLUE | New | BLUEBIRD BIO INC | $31,390,000 | – | 200,000 | – | 4.39% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $30,725,000 | – | 364,776 | – | 4.30% | – |
| FATE | New | FATE THERAPEUTICS INC | $29,484,000 | – | 2,600,000 | – | 4.12% | – |
| CDXS | New | CODEXIS INC | $29,160,000 | – | 2,025,000 | – | 4.08% | – |
| MGTA | New | MAGENTA THERAPEUTICS INC | $27,484,000 | – | 2,035,818 | – | 3.84% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $26,592,000 | – | 270,000 | – | 3.72% | – |
| VYGR | New | VOYAGER THERAPEUTICS INC | $22,178,000 | – | 1,135,000 | – | 3.10% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $21,696,000 | – | 480,000 | – | 3.03% | – |
| GNMK | New | GENMARK DIAGNOSTICS INC | $21,692,000 | – | 3,400,000 | – | 3.03% | – |
| ILMN | New | ILLUMINA INC | $19,969,000 | – | 71,500 | – | 2.79% | – |
| SGMO | New | SANGAMO THERAPEUTICS INC | $19,880,000 | – | 1,400,000 | – | 2.78% | – |
| BOLD | New | AUDENTES THERAPEUTICS INC | $17,195,000 | – | 450,000 | – | 2.40% | – |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $12,927,000 | – | 220,000 | – | 1.81% | – |
| EVH | New | EVOLENT HEALTH INCcl a | $11,578,000 | – | 550,000 | – | 1.62% | – |
| BLFS | New | BIOLIFE SOLUTIONS INC | $11,410,000 | – | 1,000,000 | – | 1.60% | – |
| BGNE | New | BEIGENE LTDsponsored adr | $10,761,000 | – | 70,000 | – | 1.50% | – |
| OSUR | New | ORASURE TECHNOLOGIES INC | $10,541,000 | – | 640,000 | – | 1.47% | – |
| CLVS | New | CLOVIS ONCOLOGY INC | $10,003,000 | – | 220,000 | – | 1.40% | – |
| EDIT | New | EDITAS MEDICINE INC | $6,390,000 | – | 178,333 | – | 0.89% | – |
| NEOG | New | NEOGEN CORP | $5,212,000 | – | 65,000 | – | 0.73% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $4,743,000 | – | 207,500 | – | 0.66% | – |
| NTGN | New | NEON THERAPEUTICS INC | $4,263,000 | – | 338,345 | – | 0.60% | – |
| LOXO | New | LOXO ONCOLOGY INCput | $3,470,000 | – | 20,000 | – | 0.48% | – |
| ZLAB | New | ZAI LAB LTDadr | $3,139,000 | – | 135,000 | – | 0.44% | – |
| JNCE | New | JOUNCE THERAPEUTICS INC | $2,873,000 | – | 375,000 | – | 0.40% | – |
| CDNA | New | CAREDX INC | $2,448,000 | – | 200,000 | – | 0.34% | – |
| FIXX | New | HOMOLOGY MEDICINES INC | $2,346,000 | – | 115,000 | – | 0.33% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS INput | $2,260,000 | – | 50,000 | – | 0.32% | – |
| BPMC | New | BLUEPRINT MEDICINES CORPcall | $635,000 | – | 10,000 | – | 0.09% | – |
Q4 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| OVID | Exit | OVID THERAPEUTICS INC | $0 | – | -207,500 | – | -0.50% | – |
| FATE | Exit | FATE THERAPEUTICS INC | $0 | – | -550,000 | – | -0.62% | – |
| EDIT | Exit | EDITAS MEDICINE INC | $0 | – | -133,333 | – | -0.90% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -177,500 | – | -0.91% | – |
| SYRS | Exit | SYROS PHARMACEUTICALS INC | $0 | – | -256,215 | – | -1.06% | – |
| TSRO | Exit | TESARO INC | $0 | – | -38,500 | – | -1.40% | – |
| JNCE | Exit | JOUNCE THERAPEUTICS INC | $0 | – | -399,825 | – | -1.76% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -44,000 | – | -2.48% | – |
| CDXS | Exit | CODEXIS INC | $0 | – | -1,475,000 | – | -2.77% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -127,500 | – | -2.97% | – |
| BOLD | Exit | AUDENTES THERAPEUTICS INC | $0 | – | -400,000 | – | -3.16% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -380,000 | – | -3.33% | – |
| EVH | Exit | EVOLENT HEALTH INCcl a | $0 | – | -795,000 | – | -4.00% | – |
| GNMK | Exit | GENMARK DIAGNOSTICS INC | $0 | – | -1,500,000 | – | -4.08% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -240,000 | – | -4.22% | – |
| VYGR | Exit | VOYAGER THERAPEUTICS INC | $0 | – | -815,000 | – | -4.74% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -255,000 | – | -4.81% | – |
| ONCE | Exit | SPARK THERAPEUTICS INC | $0 | – | -209,474 | – | -5.27% | – |
| KITE | Exit | KITE PHARMA INC | $0 | – | -106,000 | – | -5.38% | – |
| FMI | Exit | FOUNDATION MEDICINE INC | $0 | – | -480,000 | – | -5.45% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -145,000 | – | -5.62% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -298,000 | – | -5.86% | – |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -1,400,000 | – | -5.93% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -200,000 | – | -6.64% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -560,000 | – | -6.78% | – |
| LOXO | Exit | LOXO ONCOLOGY INC | $0 | – | -360,000 | – | -9.36% | – |
Q3 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MYOK | Buy | MYOKARDIA INC | $23,996,000 | +363.7% | 560,000 | +41.8% | 6.78% | +254.0% |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $23,498,000 | +180.6% | 200,000 | +90.5% | 6.64% | +114.2% |
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $20,762,000 | +49.0% | 298,000 | +8.4% | 5.86% | +13.7% |
| BLUE | Buy | BLUEBIRD BIO INC | $19,916,000 | +191.7% | 145,000 | +123.1% | 5.62% | +122.6% |
| KITE | Buy | KITE PHARMA INC | $19,060,000 | +104.3% | 106,000 | +17.8% | 5.38% | +56.0% |
| ONCE | Buy | SPARK THERAPEUTICS INC | $18,677,000 | +83.9% | 209,474 | +23.2% | 5.27% | +40.4% |
| VYGR | Buy | VOYAGER THERAPEUTICS INC | $16,781,000 | +153.1% | 815,000 | +10.1% | 4.74% | +93.2% |
| SAGE | Sell | SAGE THERAPEUTICS INC | $14,952,000 | -26.4% | 240,000 | -5.9% | 4.22% | -43.8% |
| GNMK | Buy | GENMARK DIAGNOSTICS INC | $14,445,000 | +78.2% | 1,500,000 | +119.0% | 4.08% | +36.1% |
| EVH | Buy | EVOLENT HEALTH INCcl a | $14,151,000 | +7.4% | 795,000 | +52.9% | 4.00% | -18.0% |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS IN | $11,799,000 | +100.7% | 380,000 | +76.7% | 3.33% | +53.2% |
| CLVS | Sell | CLOVIS ONCOLOGY INC | $10,506,000 | -13.7% | 127,500 | -1.9% | 2.97% | -34.1% |
| CDXS | Buy | CODEXIS INC | $9,809,000 | +51.2% | 1,475,000 | +23.9% | 2.77% | +15.5% |
| ILMN | Buy | ILLUMINA INC | $8,765,000 | +60.4% | 44,000 | +39.7% | 2.48% | +22.4% |
| JNCE | Buy | JOUNCE THERAPEUTICS INC | $6,229,000 | +177.5% | 399,825 | +149.9% | 1.76% | +111.9% |
| TSRO | Sell | TESARO INC | $4,970,000 | -26.0% | 38,500 | -19.8% | 1.40% | -43.5% |
| SYRS | Buy | SYROS PHARMACEUTICALS INC | $3,771,000 | +28.7% | 256,215 | +40.7% | 1.06% | -1.8% |
| OVID | Sell | OVID THERAPEUTICS INC | $1,778,000 | -23.6% | 207,500 | -6.4% | 0.50% | -41.6% |
| CRIS | Exit | CURIS INC | $0 | – | -85,000 | – | -0.06% | – |
| PACB | Exit | PACIFIC BIOSCIENCES CALIF IN | $0 | – | -300,000 | – | -0.40% | – |
| AMRS | Exit | AMYRIS INC | $0 | – | -500,000 | – | -0.59% | – |
| MDRX | Exit | ALLSCRIPTS HEALTHCARE SOLUTNcall | $0 | – | -150,000 | – | -0.71% | – |
| MYGN | Exit | MYRIAD GENETICS INCcall | $0 | – | -100,000 | – | -0.96% | – |
| GILD | Exit | GILEAD SCIENCES INCcall | $0 | – | -60,000 | – | -1.57% | – |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -75,000 | – | -1.96% | – |
| EPZM | Exit | EPIZYME INC | $0 | – | -520,000 | – | -2.90% | – |
| XBI | Exit | SPDR SERIES TRUSTput | $0 | – | -150,000 | – | -4.28% | – |
Q2 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| LOXO | New | LOXO ONCOLOGY INC | $28,868,000 | – | 360,000 | – | 10.68% | – |
| SAGE | New | SAGE THERAPEUTICS INC | $20,308,000 | – | 255,000 | – | 7.51% | – |
| FMI | New | FOUNDATION MEDICINE INC | $19,080,000 | – | 480,000 | – | 7.06% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $13,934,000 | – | 275,000 | – | 5.15% | – |
| EVH | New | EVOLENT HEALTH INCcl a | $13,182,000 | – | 520,000 | – | 4.88% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $13,120,000 | – | 255,000 | – | 4.85% | – |
| SGMO | New | SANGAMO THERAPEUTICS INC | $12,320,000 | – | 1,400,000 | – | 4.56% | – |
| CLVS | New | CLOVIS ONCOLOGY INC | $12,172,000 | – | 130,000 | – | 4.50% | – |
| XBI | New | SPDR SERIES TRUSTput | $11,577,000 | – | 150,000 | – | 4.28% | – |
| ONCE | New | SPARK THERAPEUTICS INC | $10,156,000 | – | 170,000 | – | 3.76% | – |
| KITE | New | KITE PHARMA INC | $9,330,000 | – | 90,000 | – | 3.45% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $8,375,000 | – | 105,000 | – | 3.10% | – |
| GNMK | New | GENMARK DIAGNOSTICS INC | $8,104,000 | – | 685,000 | – | 3.00% | – |
| EPZM | New | EPIZYME INC | $7,852,000 | – | 520,000 | – | 2.90% | – |
| BOLD | New | AUDENTES THERAPEUTICS INC | $7,652,000 | – | 400,000 | – | 2.83% | – |
| BLUE | New | BLUEBIRD BIO INC | $6,828,000 | – | 65,000 | – | 2.53% | – |
| TSRO | New | TESARO INC | $6,713,000 | – | 48,000 | – | 2.48% | – |
| VYGR | New | VOYAGER THERAPEUTICS INC | $6,630,000 | – | 740,000 | – | 2.45% | – |
| CDXS | New | CODEXIS INC | $6,486,000 | – | 1,190,000 | – | 2.40% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $5,880,000 | – | 215,000 | – | 2.18% | – |
| ILMN | New | ILLUMINA INC | $5,466,000 | – | 31,500 | – | 2.02% | – |
| GILD | New | GILEAD SCIENCES INC | $5,309,000 | – | 75,000 | – | 1.96% | – |
| MYOK | New | MYOKARDIA INC | $5,175,000 | – | 395,000 | – | 1.91% | – |
| GILD | New | GILEAD SCIENCES INCcall | $4,247,000 | – | 60,000 | – | 1.57% | – |
| SYRS | New | SYROS PHARMACEUTICALS INC | $2,931,000 | – | 182,141 | – | 1.08% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $2,751,000 | – | 177,500 | – | 1.02% | – |
| MYGN | New | MYRIAD GENETICS INCcall | $2,584,000 | – | 100,000 | – | 0.96% | – |
| OVID | New | OVID THERAPEUTICS INC | $2,326,000 | – | 221,700 | – | 0.86% | – |
| JNCE | New | JOUNCE THERAPEUTICS INC | $2,245,000 | – | 160,000 | – | 0.83% | – |
| EDIT | New | EDITAS MEDICINE INC | $2,237,000 | – | 133,333 | – | 0.83% | – |
| MDRX | New | ALLSCRIPTS HEALTHCARE SOLUTNcall | $1,914,000 | – | 150,000 | – | 0.71% | – |
| FATE | New | FATE THERAPEUTICS INC | $1,782,000 | – | 550,000 | – | 0.66% | – |
| AMRS | New | AMYRIS INC | $1,590,000 | – | 500,000 | – | 0.59% | – |
| PACB | New | PACIFIC BIOSCIENCES CALIF IN | $1,068,000 | – | 300,000 | – | 0.40% | – |
| CRIS | New | CURIS INC | $161,000 | – | 85,000 | – | 0.06% | – |
Q4 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SYRS | Exit | SYROS PHARMACEUTICALS INC | $0 | – | -50,000 | – | -0.56% | – |
| EDIT | Exit | EDITAS MEDICINE INC | $0 | – | -85,470 | – | -0.93% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -33,000 | – | -0.98% | – |
| RXDX | Exit | IGNYTA INC | $0 | – | -195,000 | – | -0.99% | – |
| IBB | Exit | ISHARES TRnasdq biotec etf | $0 | – | -5,000 | – | -1.17% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -127,500 | – | -1.62% | – |
| MDGN | Exit | MEDGENICS INC | $0 | – | -375,000 | – | -1.69% | – |
| GHDX | Exit | GENOMIC HEALTH INC | $0 | – | -90,000 | – | -2.11% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -160,000 | – | -2.12% | – |
| MDRX | Exit | ALLSCRIPTS HEALTHCARE SOLUTN | $0 | – | -200,000 | – | -2.13% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -39,000 | – | -2.14% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -155,000 | – | -2.33% | – |
| EPZM | Exit | EPIZYME INC | $0 | – | -295,000 | – | -2.35% | – |
| VYGR | Exit | VOYAGER THERAPEUTICS INC | $0 | – | -276,500 | – | -2.69% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -110,000 | – | -3.21% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -60,000 | – | -3.29% | – |
| KITE | Exit | KITE PHARMA INC | $0 | – | -90,000 | – | -4.07% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -240,000 | – | -4.48% | – |
| ONCE | Exit | SPARK THERAPEUTICS INC | $0 | – | -93,500 | – | -4.55% | – |
| GNMK | Exit | GENMARK DIAGNOSTICS INC | $0 | – | -625,000 | – | -5.97% | – |
| LOXO | Exit | LOXO ONCOLOGY INC | $0 | – | -291,000 | – | -6.17% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -287,000 | – | -6.90% | – |
| EVH | Exit | EVOLENT HEALTH INCcl a | $0 | – | -385,000 | – | -7.68% | – |
| FMI | Exit | FOUNDATION MEDICINE INC | $0 | – | -415,000 | – | -7.85% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -266,500 | – | -9.94% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -282,443 | – | -12.08% | – |
Q3 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| AGIO | Buy | AGIOS PHARMACEUTICALS INC | $14,919,000 | +89.9% | 282,443 | +50.6% | 12.08% | +54.5% |
| SAGE | Buy | SAGE THERAPEUTICS INC | $12,272,000 | +78.2% | 266,500 | +16.6% | 9.94% | +45.0% |
| FMI | Buy | FOUNDATION MEDICINE INC | $9,690,000 | +33.2% | 415,000 | +6.4% | 7.85% | +8.3% |
| EVH | Buy | EVOLENT HEALTH INCcl a | $9,479,000 | +106.2% | 385,000 | +60.8% | 7.68% | +67.7% |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $8,524,000 | +23.8% | 287,000 | -15.6% | 6.90% | +0.7% |
| LOXO | Sell | LOXO ONCOLOGY INC | $7,618,000 | +9.5% | 291,000 | -3.0% | 6.17% | -10.9% |
| GNMK | Buy | GENMARK DIAGNOSTICS INC | $7,375,000 | +104.2% | 625,000 | +50.6% | 5.97% | +66.2% |
| ONCE | Sell | SPARK THERAPEUTICS INC | $5,616,000 | -32.4% | 93,500 | -42.5% | 4.55% | -45.0% |
| GBT | Sell | GLOBAL BLOOD THERAPEUTICS IN | $5,532,000 | -22.5% | 240,000 | -44.2% | 4.48% | -36.9% |
| KITE | Buy | KITE PHARMA INC | $5,027,000 | +38.7% | 90,000 | +24.1% | 4.07% | +12.8% |
| BLUE | Sell | BLUEBIRD BIO INC | $4,067,000 | -23.3% | 60,000 | -51.0% | 3.29% | -37.6% |
| CLVS | Sell | CLOVIS ONCOLOGY INC | $3,966,000 | +92.7% | 110,000 | -26.7% | 3.21% | +56.8% |
| VYGR | Sell | VOYAGER THERAPEUTICS INC | $3,321,000 | -6.3% | 276,500 | -14.3% | 2.69% | -23.8% |
| EPZM | Sell | EPIZYME INC | $2,903,000 | -16.6% | 295,000 | -13.2% | 2.35% | -32.2% |
| EXAS | New | EXACT SCIENCES CORP | $2,878,000 | – | 155,000 | – | 2.33% | – |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $2,643,000 | -34.3% | 39,000 | -46.2% | 2.14% | -46.6% |
| MDRX | New | ALLSCRIPTS HEALTHCARE SOLUTN | $2,634,000 | – | 200,000 | – | 2.13% | – |
| MYOK | Sell | MYOKARDIA INC | $2,614,000 | +17.7% | 160,000 | -10.6% | 2.12% | -4.2% |
| GHDX | New | GENOMIC HEALTH INC | $2,603,000 | – | 90,000 | – | 2.11% | – |
| MDGN | Buy | MEDGENICS INC | $2,089,000 | +342.6% | 375,000 | +341.2% | 1.69% | +260.0% |
| CTMX | Sell | CYTOMX THERAPEUTICS INC | $1,999,000 | -16.4% | 127,500 | -45.6% | 1.62% | -32.0% |
| IBB | New | ISHARES TRnasdq biotec etf | $1,447,000 | – | 5,000 | – | 1.17% | – |
| RXDX | Sell | IGNYTA INC | $1,227,000 | -39.6% | 195,000 | -48.0% | 0.99% | -50.9% |
| IONS | New | IONIS PHARMACEUTICALS INC | $1,209,000 | – | 33,000 | – | 0.98% | – |
| EDIT | New | EDITAS MEDICINE INC | $1,152,000 | – | 85,470 | – | 0.93% | – |
| DXCM | Exit | DEXCOM INCput | $0 | – | -15,000 | – | -1.18% | – |
| DXCM | Exit | DEXCOM INC | $0 | – | -15,000 | – | -1.18% | – |
| BMY | Exit | BRISTOL MYERS SQUIBB CO | $0 | – | -21,000 | – | -1.54% | – |
| XBI | Exit | SPDR SERIES TRUSTput | $0 | – | -30,000 | – | -1.61% | – |
| TSRO | Exit | TESARO INC | $0 | – | -20,000 | – | -1.67% | – |
| AVXS | Exit | AVEXIS INC | $0 | – | -45,000 | – | -1.70% | – |
| SAGE | Exit | SAGE THERAPEUTICS INCcall | $0 | – | -65,000 | – | -1.95% | – |
Q2 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ONCE | New | SPARK THERAPEUTICS INC | $8,309,000 | – | 162,500 | – | 8.27% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $7,855,000 | – | 187,500 | – | 7.82% | – |
| FMI | New | FOUNDATION MEDICINE INC | $7,277,000 | – | 390,000 | – | 7.24% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $7,134,000 | – | 430,000 | – | 7.10% | – |
| LOXO | New | LOXO ONCOLOGY INC | $6,954,000 | – | 300,000 | – | 6.92% | – |
| SAGE | New | SAGE THERAPEUTICS INC | $6,885,000 | – | 228,500 | – | 6.85% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $6,885,000 | – | 340,000 | – | 6.85% | – |
| BLUE | New | BLUEBIRD BIO INC | $5,303,000 | – | 122,500 | – | 5.28% | – |
| EVH | New | EVOLENT HEALTH INCcl a | $4,598,000 | – | 239,500 | – | 4.58% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $4,023,000 | – | 72,500 | – | 4.00% | – |
| KITE | New | KITE PHARMA INC | $3,625,000 | – | 72,500 | – | 3.61% | – |
| GNMK | New | GENMARK DIAGNOSTICS INC | $3,611,000 | – | 415,000 | – | 3.59% | – |
| VYGR | New | VOYAGER THERAPEUTICS INC | $3,544,000 | – | 322,500 | – | 3.53% | – |
| EPZM | New | EPIZYME INC | $3,482,000 | – | 340,000 | – | 3.47% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $2,392,000 | – | 234,179 | – | 2.38% | – |
| MYOK | New | MYOKARDIA INC | $2,220,000 | – | 179,029 | – | 2.21% | – |
| CLVS | New | CLOVIS ONCOLOGY INC | $2,058,000 | – | 150,000 | – | 2.05% | – |
| RXDX | New | IGNYTA INC | $2,033,000 | – | 375,000 | – | 2.02% | – |
| SAGE | New | SAGE THERAPEUTICS INCcall | $1,958,000 | – | 65,000 | – | 1.95% | – |
| AVXS | New | AVEXIS INC | $1,711,000 | – | 45,000 | – | 1.70% | – |
| TSRO | New | TESARO INC | $1,681,000 | – | 20,000 | – | 1.67% | – |
| XBI | New | SPDR SERIES TRUSTput | $1,622,000 | – | 30,000 | – | 1.61% | – |
| BMY | New | BRISTOL MYERS SQUIBB CO | $1,545,000 | – | 21,000 | – | 1.54% | – |
| DXCM | New | DEXCOM INCput | $1,190,000 | – | 15,000 | – | 1.18% | – |
| DXCM | New | DEXCOM INC | $1,190,000 | – | 15,000 | – | 1.18% | – |
| SYRS | New | SYROS PHARMACEUTICALS INC | $908,000 | – | 50,000 | – | 0.90% | – |
| MDGN | New | MEDGENICS INC | $472,000 | – | 85,000 | – | 0.47% | – |