$3.36 Billion is the total value of Casdin Capital, LLC's 48 reported holdings in Q1 2021. The portfolio turnover from Q4 2020 to Q1 2021 was 23.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NVTA | Sell | INVITAE CORP | $466,302,000 | -9.3% | 12,203,669 | -0.8% | 13.89% | -8.8% |
| EXAS | Buy | EXACT SCIENCES CORP | $311,025,000 | +58.1% | 2,360,186 | +58.9% | 9.26% | +58.9% |
| FATE | Buy | FATE THERAPEUTICS INC | $280,330,000 | +1.1% | 3,400,000 | +11.5% | 8.35% | +1.6% |
| BLFS | BIOLIFE SOLUTIONS INC | $267,844,000 | -9.8% | 7,440,107 | 0.0% | 7.98% | -9.3% | |
| PACB | PACIFIC BIOSCIENCES CALIF IN | $166,550,000 | +28.4% | 5,000,000 | 0.0% | 4.96% | +29.1% | |
| BPMC | BLUEPRINT MEDICINES CORP | $150,707,000 | -13.3% | 1,550,000 | 0.0% | 4.49% | -12.8% | |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $124,247,000 | +22.6% | 880,000 | +12.8% | 3.70% | +23.2% |
| TWST | TWIST BIOSCIENCE CORP | $123,860,000 | -12.3% | 1,000,000 | 0.0% | 3.69% | -11.9% | |
| RLAY | Sell | RELAY THERAPEUTICS INC | $116,676,000 | -26.3% | 3,375,058 | -11.4% | 3.48% | -25.9% |
| AGIO | Sell | AGIOS PHARMACEUTICALS INC | $111,801,000 | +8.6% | 2,165,000 | -8.8% | 3.33% | +9.2% |
| CDXS | CODEXIS INC | $99,114,000 | +4.9% | 4,330,000 | 0.0% | 2.95% | +5.4% | |
| DNLI | Buy | DENALI THERAPEUTICS INC | $91,931,000 | -16.2% | 1,610,000 | +22.9% | 2.74% | -15.8% |
| Buy | DERMTECH INC | $88,629,000 | +99.4% | 1,745,000 | +27.4% | 2.64% | +100.5% | |
| RVMD | Buy | REVOLUTION MEDICINES INC | $84,627,000 | +30.8% | 1,844,535 | +12.8% | 2.52% | +31.5% |
| CDNA | CAREDX INC | $81,254,000 | -6.0% | 1,193,335 | 0.0% | 2.42% | -5.5% | |
| BEAM | Buy | BEAM THERAPEUTICS INC | $65,538,000 | +74.5% | 818,820 | +78.0% | 1.95% | +75.4% |
| BGNE | BEIGENE LTDsponsored adr | $52,212,000 | +34.7% | 150,000 | 0.0% | 1.56% | +35.5% | |
| ADPT | Buy | ADAPTIVE BIOTECHNOLOGIES COR | $46,299,000 | +9.8% | 1,150,000 | +61.3% | 1.38% | +10.4% |
| ALLO | Buy | ALLOGENE THERAPEUTICS INC | $45,890,000 | +92.4% | 1,300,000 | +37.6% | 1.37% | +93.4% |
| GBIO | GENERATION BIO CO | $45,855,000 | +0.4% | 1,611,214 | 0.0% | 1.37% | +1.0% | |
| FDMT | Buy | 4D MOLECULAR THERAPEUTICS IN | $43,178,000 | +33.5% | 995,354 | +27.5% | 1.29% | +34.1% |
| CNST | Buy | CONSTELLATION PHARMCETICLS I | $42,102,000 | -18.1% | 1,800,000 | +0.8% | 1.25% | -17.7% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $40,992,000 | -54.6% | 550,000 | +3.8% | 1.22% | -54.4% |
| MGTA | MAGENTA THERAPEUTICS INC | $39,617,000 | +51.0% | 3,346,034 | 0.0% | 1.18% | +51.9% | |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS IN | $36,675,000 | +4.5% | 900,000 | +11.1% | 1.09% | +5.1% |
| ALEC | ALECTOR INC | $33,231,000 | +33.1% | 1,650,000 | 0.0% | 0.99% | +33.8% | |
| CRSP | CRISPR THERAPEUTICS AGnamen akt | $32,464,000 | -20.4% | 266,430 | 0.0% | 0.97% | -20.0% | |
| ZLAB | ZAI LAB LTDadr | $25,352,000 | -1.4% | 190,000 | 0.0% | 0.76% | -0.9% | |
| ORTX | New | ORCHARD THERAPEUTICS PLCads | $23,344,000 | – | 3,215,434 | +100.0% | 0.70% | – |
| BNR | Sell | BURNING ROCK BIOTECH LTDsponsored adr | $22,805,000 | -48.6% | 847,150 | -55.9% | 0.68% | -48.4% |
| SNDX | Buy | SYNDAX PHARMACEUTICALS INC | $22,360,000 | +123.4% | 1,000,000 | +122.2% | 0.67% | +125.0% |
| ADVM | Sell | ADVERUM BIOTECHNOLOGIES INC | $21,807,000 | -44.9% | 2,211,622 | -39.4% | 0.65% | -44.6% |
| MASS | 908 DEVICES INC | $19,715,000 | -14.8% | 406,502 | 0.0% | 0.59% | -14.4% | |
| KRON | KRONOS BIO INC | $17,077,000 | -2.0% | 583,436 | 0.0% | 0.51% | -1.4% | |
| TSHA | TAYSHA GENE THERAPIES INC | $16,655,000 | -23.5% | 820,440 | 0.0% | 0.50% | -23.1% | |
| ORIC | ORIC PHARMACEUTICALS INC | $14,737,000 | -27.6% | 601,515 | 0.0% | 0.44% | -27.2% | |
| FULC | FULCRUM THERAPEUTICS INC | $14,621,000 | +0.6% | 1,241,176 | 0.0% | 0.44% | +0.9% | |
| DBTX | New | DECIBEL THERAPEUTICS INC | $13,023,000 | – | 1,146,421 | +100.0% | 0.39% | – |
| BLI | BERKELEY LTS INC | $10,046,000 | -43.8% | 200,000 | 0.0% | 0.30% | -43.6% | |
| DYN | Buy | DYNE THERAPEUTICS INC | $9,473,000 | +21.9% | 610,000 | +64.9% | 0.28% | +22.6% |
| SEER | SEER INC | $7,503,000 | -10.9% | 150,000 | 0.0% | 0.22% | -10.4% | |
| TPTX | TURNING POINT THERAPEUTICS I | $7,094,000 | -22.4% | 75,000 | 0.0% | 0.21% | -22.1% | |
| SGMO | Sell | SANGAMO THERAPEUTICS INC | $6,892,000 | -59.1% | 550,000 | -49.1% | 0.20% | -58.9% |
| CLOV | New | CLOVER HEALTH INVESTMENTS CO | $5,492,000 | – | 726,511 | +100.0% | 0.16% | – |
| STOK | STOKE THERAPEUTICS INC | $4,661,000 | -37.3% | 120,000 | 0.0% | 0.14% | -36.8% | |
| FHTX | FOGHORN THERAPEUTICS INC | $2,850,000 | -35.0% | 216,216 | 0.0% | 0.08% | -34.6% | |
| SANA | New | SANA BIOTECHNOLOGY INC | $2,008,000 | – | 60,000 | +100.0% | 0.06% | – |
| CDAK | CODIAK BIOSCIENCES INC | $1,156,000 | -53.3% | 76,688 | 0.0% | 0.03% | -53.4% | |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -40,000 | -100.0% | -0.04% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS INcall | $0 | – | -50,000 | -100.0% | -0.06% | – |
| BMYRT | Exit | BRISTOL-MYERS SQUIBB COright 99/99/9999 | $0 | – | -6,250,000 | -100.0% | -0.13% | – |
| ABCL | Exit | ABCELLERA BIOLOGICS INC | $0 | – | -200,000 | -100.0% | -0.24% | – |
| BDTX | Exit | BLACK DIAMOND THERAPEUTICS I | $0 | – | -289,395 | -100.0% | -0.28% | – |
| AMRS | Exit | AMYRIS INCcall | $0 | – | -2,000,000 | -100.0% | -0.37% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -550,000 | -100.0% | -0.76% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -915,000 | -100.0% | -1.17% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-05-17
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| BLUEPRINT MEDICINES CORP | 32 | Q3 2023 | 9.6% |
| ALNYLAM PHARMACEUTICALS INC | 32 | Q3 2023 | 9.9% |
| AGIOS PHARMACEUTICALS INC | 27 | Q2 2022 | 12.1% |
| GLOBAL BLOOD THERAPEUTICS IN | 27 | Q2 2022 | 7.1% |
| FATE THERAPEUTICS INC | 26 | Q3 2023 | 8.3% |
| BIOLIFE SOLUTIONS INC | 22 | Q3 2023 | 14.9% |
| CODEXIS INC | 22 | Q3 2023 | 8.1% |
| SAREPTA THERAPEUTICS INC | 21 | Q3 2023 | 13.6% |
| BLUEBIRD BIO INC | 21 | Q4 2020 | 7.8% |
| ILLUMINA INC | 21 | Q3 2023 | 6.0% |
View Casdin Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Absci Corp | May 08, 2023 | 4,448,260 | 4.8% |
| CODEXIS, INC.Sold out | February 14, 2023 | 0 | 0.0% |
| DermTech, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Invitae Corp | February 14, 2023 | 9,038,388 | 3.7% |
| Magenta Therapeutics, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Tango Therapeutics, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Verve Therapeutics, Inc. | February 14, 2023 | 2,290,571 | 3.7% |
| Tenaya Therapeutics, Inc. | December 07, 2022 | 6,427,200 | 9.9% |
| Fulcrum Therapeutics, Inc. | February 11, 2021 | 1,241,176 | 4.5% |
| Gritstone Oncology, Inc.Sold out | February 11, 2021 | 0 | 0.0% |
View Casdin Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-04-18 |
| SC 13D/A | 2024-04-08 |
| 4 | 2024-03-28 |
| 3 | 2024-03-25 |
| 4 | 2024-03-25 |
| 4 | 2024-03-20 |
| SC 13D/A | 2024-03-20 |
| 4 | 2024-03-06 |
| 4 | 2024-03-06 |
| 13F-HR | 2024-02-14 |
View Casdin Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.