$647 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 80 reported holdings in Q3 2019. The portfolio turnover from Q2 2019 to Q3 2019 was 56.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BMY | Buy | BRISTOL MYERS SQUIBB CO | $56,283,000 | +33.5% | 1,109,900 | +19.4% | 8.70% | +50.7% |
| JNJ | JOHNSON & JOHNSON | $51,752,000 | -7.1% | 400,000 | 0.0% | 8.00% | +4.9% | |
| GILD | New | GILEAD SCIENCES INC | $44,683,000 | – | 705,000 | +100.0% | 6.90% | – |
| MRK | Buy | MERCK & CO INC | $39,565,000 | +4.4% | 470,000 | +4.0% | 6.11% | +17.9% |
| SNY | New | SANOFIsponsored adr | $32,431,000 | – | 700,000 | +100.0% | 5.01% | – |
| CELG | CELGENE CORP | $24,825,000 | +7.4% | 250,000 | 0.0% | 3.84% | +21.3% | |
| FOLD | Buy | AMICUS THERAPEUTICS INC | $23,501,000 | -25.0% | 2,930,320 | +16.7% | 3.63% | -15.3% |
| NVO | New | NOVO-NORDISK A Sadr | $23,265,000 | – | 450,000 | +100.0% | 3.59% | – |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $18,682,000 | +173.2% | 248,038 | +451.2% | 2.89% | +208.7% |
| ALXN | Sell | ALEXION PHARMACEUTICALS INC | $16,230,000 | -63.2% | 165,713 | -50.8% | 2.51% | -58.5% |
| ARQL | Buy | ARQULE INC | $14,933,000 | -23.9% | 2,082,643 | +16.8% | 2.31% | -14.1% |
| TEVA | Buy | TEVA PHARMACEUTICAL INDS LTD | $10,664,000 | +45.5% | 1,550,000 | +95.3% | 1.65% | +64.4% |
| PTCT | New | PTC THERAPEUTICS INC | $10,484,000 | – | 310,000 | +100.0% | 1.62% | – |
| GWPH | New | GW PHARMACEUTICALS PLCads | $8,512,000 | – | 74,000 | +100.0% | 1.32% | – |
| MLNX | Buy | MELLANOX TECHNOLOGIES LTD | $8,425,000 | +227.9% | 76,875 | +231.1% | 1.30% | +270.9% |
| NICE | Buy | NICE LTDsponsored adr | $8,224,000 | +3284.4% | 57,193 | +3129.4% | 1.27% | +3748.5% |
| DRNA | Buy | DICERNA PHARMACEUTICALS INC | $8,113,000 | +63.7% | 565,000 | +79.6% | 1.25% | +84.8% |
| URGN | Buy | UROGEN PHARMA LTD | $8,003,000 | -27.8% | 335,817 | +8.9% | 1.24% | -18.5% |
| RCKT | Buy | ROCKET PHARMACEUTICALS INC | $7,689,000 | +65.4% | 660,000 | +112.9% | 1.19% | +86.8% |
| CSTE | Sell | CAESARSTONE LTD | $7,666,000 | -5.3% | 461,509 | -14.3% | 1.18% | +7.0% |
| MSFT | MICROSOFT CORP | $7,472,000 | +3.8% | 53,741 | 0.0% | 1.15% | +17.2% | |
| STOK | Sell | STOKE THERAPEUTICS INC | $7,384,000 | -24.0% | 346,380 | -1.3% | 1.14% | -14.1% |
| ASND | ASCENDIS PHARMA A Ssponsored adr | $7,106,000 | -16.4% | 73,773 | 0.0% | 1.10% | -5.5% | |
| QURE | Buy | UNIQURE NV | $6,986,000 | +48.6% | 177,500 | +195.1% | 1.08% | +67.8% |
| PTLA | New | PORTOLA PHARMACEUTICALS INC | $6,973,000 | – | 260,000 | +100.0% | 1.08% | – |
| FISV | Buy | FISERV INC | $6,969,000 | +89.4% | 67,279 | +66.7% | 1.08% | +114.1% |
| PANW | Buy | PALO ALTO NETWORKS INC | $6,721,000 | +17.9% | 32,976 | +17.9% | 1.04% | +33.1% |
| SWTX | New | SPRINGWORKS THERAPEUTICS INC | $6,721,000 | – | 310,000 | +100.0% | 1.04% | – |
| XCUR | New | EXICURE INC | $6,674,000 | – | 2,637,988 | +100.0% | 1.03% | – |
| FSCT | Buy | FORESCOUT TECHNOLOGIES INC | $6,587,000 | +12.5% | 173,696 | +0.5% | 1.02% | +27.1% |
| AUDC | Sell | AUDIOCODES LTDord | $6,207,000 | -12.1% | 328,263 | -28.0% | 0.96% | -0.7% |
| NERV | Buy | MINERVA NEUROSCIENCES INC | $5,906,000 | +39.5% | 762,018 | +1.3% | 0.91% | +57.5% |
| NEOS | Buy | NEOS THERAPEUTICS INC | $5,784,000 | +20.8% | 3,908,265 | +5.3% | 0.89% | +36.5% |
| VRNT | Sell | VERINT SYS INC | $5,753,000 | -75.3% | 134,489 | -68.9% | 0.89% | -72.1% |
| ALDX | ALDEYRA THERAPEUTICS INC | $5,634,000 | -12.2% | 1,069,089 | 0.0% | 0.87% | -0.9% | |
| SEDG | Sell | SOLAREDGE TECHNOLOGIES INC | $5,358,000 | -50.3% | 64,002 | -63.0% | 0.83% | -43.9% |
| ALLT | ALLOT LTD | $5,328,000 | +11.8% | 661,031 | 0.0% | 0.82% | +26.2% | |
| PRQR | Buy | PROQR THRAPEUTICS N V | $5,270,000 | +23.2% | 915,000 | +94.7% | 0.81% | +39.1% |
| HARP | HARPOON THERAPEUTICS INC | $5,109,000 | +5.1% | 374,031 | 0.0% | 0.79% | +18.6% | |
| RETA | Sell | REATA PHARMACEUTICALS INCcl a | $5,080,000 | -52.3% | 63,269 | -43.9% | 0.78% | -46.1% |
| YMAB | Y MABS THERAPEUTICS INC | $4,951,000 | +13.9% | 190,000 | 0.0% | 0.76% | +28.8% | |
| CHMA | New | CHIASMA INC | $4,901,000 | – | 990,000 | +100.0% | 0.76% | – |
| ARVN | ARVINAS INC | $4,424,000 | -2.0% | 205,281 | 0.0% | 0.68% | +10.5% | |
| ARGX | ARGENX SEsponsored adr | $4,397,000 | -19.5% | 38,581 | 0.0% | 0.68% | -9.1% | |
| AXGT | AXOVANT GENE THERAPIES LTD | $4,319,000 | +3.7% | 668,541 | 0.0% | 0.67% | +17.0% | |
| WIX | Buy | WIX COM LTD | $4,307,000 | +46.5% | 36,890 | +78.3% | 0.66% | +65.4% |
| ZYME | New | ZYMEWORKS INC | $4,216,000 | – | 170,000 | +100.0% | 0.65% | – |
| KRYS | KRYSTAL BIOTECH INC | $4,085,000 | -13.8% | 117,625 | 0.0% | 0.63% | -2.6% | |
| KRNT | Sell | KORNIT DIGITAL LTD | $4,050,000 | -29.4% | 131,588 | -27.4% | 0.63% | -20.3% |
| BURL | BURLINGTON STORES INC | $3,896,000 | +17.4% | 19,500 | 0.0% | 0.60% | +32.6% | |
| STRO | Sell | SUTRO BIOPHARMA INC | $3,841,000 | -24.3% | 422,589 | -5.2% | 0.59% | -14.6% |
| RTRX | Sell | RETROPHIN INC | $3,827,000 | -64.1% | 330,203 | -37.8% | 0.59% | -59.5% |
| AMZN | Sell | AMAZON COM INC | $3,819,000 | -52.0% | 2,200 | -47.6% | 0.59% | -45.8% |
| ITRN | Buy | ITURAN LOCATION AND CONTROL | $3,354,000 | -14.3% | 135,311 | +4.1% | 0.52% | -3.2% |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $3,239,000 | – | 90,000 | +100.0% | 0.50% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $3,122,000 | – | 42,500 | +100.0% | 0.48% | – |
| DTIL | Buy | PRECISION BIOSCIENCES INC | $3,062,000 | -31.0% | 365,000 | +9.0% | 0.47% | -22.1% |
| AKRO | New | AKERO THERAPEUTICS INC | $2,958,000 | – | 130,000 | +100.0% | 0.46% | – |
| WAB | WABTEC CORP | $2,874,000 | +0.1% | 40,000 | 0.0% | 0.44% | +13.0% | |
| ALNA | Buy | ALLENA PHARMACEUTICALS INC | $2,655,000 | +32.8% | 673,881 | +37.2% | 0.41% | +50.2% |
| FVRR | Buy | FIVERR INTL LTD | $2,643,000 | +27.1% | 141,355 | +101.9% | 0.41% | +43.7% |
| CHTR | CHARTER COMMUNICATIONS INC Ncl a | $2,473,000 | +4.3% | 6,000 | 0.0% | 0.38% | +17.9% | |
| ARYAU | ARYA SCIENCES ACQUISITION COunit 10/04/2023 | $2,188,000 | +2.3% | 200,000 | 0.0% | 0.34% | +15.8% | |
| DK | Buy | DELEK US HLDGS INC NEW | $1,815,000 | +437.0% | 50,000 | +499.0% | 0.28% | +508.7% |
| AVRO | New | AVROBIO INC | $1,784,000 | – | 126,324 | +100.0% | 0.28% | – |
| NVMI | New | NOVA MEASURING INSTRUMENTS L | $1,650,000 | – | 51,949 | +100.0% | 0.26% | – |
| SNSS | New | SUNESIS PHARMACEUTICALS INC | $1,542,000 | – | 2,141,800 | +100.0% | 0.24% | – |
| ASMB | New | ASSEMBLY BIOSCIENCES INC | $1,180,000 | – | 120,000 | +100.0% | 0.18% | – |
| PRVL | Sell | PREVAIL THERAPEUTICS INC | $1,108,000 | -35.9% | 90,217 | -31.1% | 0.17% | -27.5% |
| HSACU | HEALTH SCIENCES ACQUSTN CORPunit 04/01/2024 | $1,073,000 | +1.7% | 100,000 | 0.0% | 0.17% | +15.3% | |
| CNCE | New | CONCERT PHARMACEUTICALS INC | $823,000 | – | 140,000 | +100.0% | 0.13% | – |
| BLCM | New | BELLICUM PHARMACEUTICALS INC | $788,000 | – | 750,000 | +100.0% | 0.12% | – |
| ABUS | ARBUTUS BIOPHARMA CORP | $763,000 | -26.6% | 500,000 | 0.0% | 0.12% | -16.9% | |
| XFOR | X4 PHARMACEUTICALS INC | $602,000 | -15.3% | 47,391 | 0.0% | 0.09% | -4.1% | |
| ERYP | Sell | ERYTECH PHARMAsponsored adr | $523,000 | -38.7% | 117,837 | -1.0% | 0.08% | -30.8% |
| CUE | CUE BIOPHARMA INC | $422,000 | -6.2% | 50,000 | 0.0% | 0.06% | +4.8% | |
| MRSN | MERSANA THERAPEUTICS INC | $316,000 | -61.0% | 200,000 | 0.0% | 0.05% | -55.9% | |
| TUFN | New | TUFIN SOFTWARE TECHNOLOGIS L | $201,000 | – | 12,231 | +100.0% | 0.03% | – |
| CLRB | CELLECTAR BIOSCIENCES INC | $175,000 | -8.4% | 87,500 | 0.0% | 0.03% | +3.8% | |
| BNTC | Exit | BENITEC BIOPHARMA LTDspons adr new | $0 | – | -40,000 | -100.0% | -0.00% | – |
| MRNS | Exit | MARINUS PHARMACEUTICALS INC | $0 | – | -80,000 | -100.0% | -0.04% | – |
| VTGN | Exit | VISTAGEN THERAPEUTICS INC | $0 | – | -673,628 | -100.0% | -0.07% | – |
| KZR | Exit | KEZAR LIFE SCIENCES INC | $0 | – | -69,200 | -100.0% | -0.07% | – |
| AGLE | Exit | AEGLEA BIOTHERAPEUTICS INC | $0 | – | -187,206 | -100.0% | -0.18% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCads | $0 | – | -107,433 | -100.0% | -0.21% | – |
| MGIC | Exit | MAGIC SOFTWARE ENTERPRISES Lord | $0 | – | -185,288 | -100.0% | -0.23% | – |
| RDWR | Exit | RADWARE LTDord | $0 | – | -102,277 | -100.0% | -0.35% | – |
| AAP | Exit | ADVANCE AUTO PARTS INC | $0 | – | -17,400 | -100.0% | -0.37% | – |
| Exit | INTEC PHARMA LTD JERUSALEM | $0 | – | -620,000 | -100.0% | -0.37% | – | |
| AUTL | Exit | AUTOLUS THERAPEUTICS PLCspon ads | $0 | – | -177,546 | -100.0% | -0.39% | – |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -281,291 | -100.0% | -0.42% | – |
| CAMT | Exit | CAMTEK LTDord | $0 | – | -417,459 | -100.0% | -0.48% | – |
| ITCI | Exit | INTRA CELLULAR THERAPIES INCcall | $0 | – | -300,000 | -100.0% | -0.53% | – |
| IFF | Exit | INTERNATIONAL FLAVORS&FRAGRA | $0 | – | -30,000 | -100.0% | -0.60% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -95,564 | -100.0% | -0.67% | – |
| TLT | Exit | ISHARES TR20 yr tr bd etf | $0 | – | -45,000 | -100.0% | -0.82% | – |
| XHB | Exit | SPDR SERIES TRUSTs&p homebuild | $0 | – | -166,796 | -100.0% | -0.95% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -140,000 | -100.0% | -0.96% | – |
| MYL | Exit | MYLAN N V | $0 | – | -400,000 | -100.0% | -1.04% | – |
| WVE | Exit | WAVE LIFE SCIENCES LTD | $0 | – | -307,967 | -100.0% | -1.10% | – |
| IFF | Exit | INTERNATIONAL FLAVORS&FRAGRAcall | $0 | – | -63,500 | -100.0% | -1.26% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS IN | $0 | – | -116,000 | -100.0% | -1.26% | – |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -30,000 | -100.0% | -1.28% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -75,000 | -100.0% | -1.30% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INCcall | $0 | – | -120,000 | -100.0% | -2.49% | – |
| TEVA | Exit | TEVA PHARMACEUTICAL INDS LTDcall | $0 | – | -2,050,000 | -100.0% | -2.59% | – |
| GSK | Exit | GLAXOSMITHKLINE PLCsponsored adr | $0 | – | -500,000 | -100.0% | -2.74% | – |
| QURE | Exit | UNIQURE NVcall | $0 | – | -265,000 | -100.0% | -2.83% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -770,000 | -100.0% | -4.35% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2019-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
| SC 13G | 2023-08-30 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.