SPHERA FUNDS MANAGEMENT LTD. - Q3 2014 holdings

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$809 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 132 reported holdings in Q3 2014. The portfolio turnover from Q2 2014 to Q3 2014 was 92.9% .

All
New
Buy
Sell
Exit
Unchanged
 Value Shares↓ Weighting
NVS SellNOVARTIS AG-REGsponsored adr$45,179,000
-6.4%
478,921
-10.2%
5.58%
-53.1%
NewSPDR S&P 500 ETF Trustput$39,404,000–200,000
+100.0%
4.87%–
PFE BuyPFIZER INC$37,673,000
+93.9%
1,274,013
+94.6%
4.65%
-2.8%
TEVA BuyTEVA PHARMACEUTICAL-SP ADRadr$34,845,000
+49.5%
647,438
+45.7%
4.30%
-25.0%
NewHealth Care Select Sector SPDRput$31,028,000–485,500
+100.0%
3.83%–
B108PS NewACTAVIS PLC$29,460,000–122,100
+100.0%
3.64%–
MRK SellMERCK & CO. INC.$24,751,000
-0.5%
417,530
-2.9%
3.06%
-50.1%
ABBV NewABBVIE INC$23,309,000–403,550
+100.0%
2.88%–
BuyALLERGAN INC$22,958,000
+239.2%
128,840
+222.1%
2.84%
+70.0%
SHPG BuySHIRE PLCsponsored adr$22,429,000
+59.5%
259,085
+43.9%
2.77%
-20.1%
ISRL NewIsramco Negev 2 LP$22,136,000–103,111,944
+100.0%
2.74%–
JNJ SellJOHNSON & JOHNSON$22,107,000
-1.1%
207,406
-2.9%
2.73%
-50.4%
BuyGILEAD SCIENCES INCcall$20,673,000
+929.5%
194,200
+9610.0%
2.55%
+416.0%
BuyTeva Pharmaceutical Industriescall$20,167,000
+1526.4%
375,200
+11588.5%
2.49%
+714.1%
VRTX NewVERTEX PHARMACEUTICALS INC$16,847,000–150,000
+100.0%
2.08%–
BuyGLAXOSMITHKLINE PLC-SPON ADRcall$13,391,000
+1818.5%
291,300
+9610.0%
1.65%
+861.6%
VRX NewVALEANT PHARMACEUTICALS INTE$12,930,000–98,550
+100.0%
1.60%–
NewVALEANT PHARMACEUTICALS INTEcall$12,753,000–97,200
+100.0%
1.58%–
MNKKQ NewMALLINCKRODT PLC$12,255,000–135,940
+100.0%
1.51%–
UTHR NewUNITED THERAPEUTICS CORP$11,429,000–88,840
+100.0%
1.41%–
ICL NewIsrael Chemicals Ltd$9,977,000–1,380,000
+100.0%
1.23%–
ESLT NewElbit Systems Ltdord$8,974,000–144,759
+100.0%
1.11%–
ORBK BuyOrbotech Ltdord$8,901,000
+70.6%
571,532
+66.3%
1.10%
-14.4%
BMRN BuyBIOMARIN PHARMACEUTICAL INC$8,801,000
+17.9%
121,970
+1.6%
1.09%
-40.9%
NewASTRAZENECA PLC-SPONS ADRsponsored adr$8,573,000–120,000
+100.0%
1.06%–
VRNT BuyVerint Systems Inc$8,423,000
+27.6%
151,468
+12.6%
1.04%
-36.0%
GCVRZ NewSANOFIright 12/31/2020$7,689,000–67,960
+100.0%
0.95%–
BuySALIX PHARMACEUTICALS LTDcall$7,578,000
+728.2%
48,500
+9600.0%
0.94%
+316.0%
PBYI BuyPUMA BIOTECHNOLOGY INC$7,228,000
+338.1%
30,296
+21.2%
0.89%
+119.4%
NewASTRAZENECA PLC-SPONS ADRcall$6,937,000–97,100
+100.0%
0.86%–
BuyAMGEN INC$6,819,000
+44.0%
48,550
+21.4%
0.84%
-27.8%
ACOR BuyACORDA THERAPEUTICS INC$6,746,000
+33.4%
199,105
+32.7%
0.83%
-33.1%
LLY SellELI LILLY & CO$6,297,000
+1.3%
97,100
-2.9%
0.78%
-49.2%
MDVN SellMEDIVATION INC$6,240,000
+15.6%
63,115
-9.8%
0.77%
-42.0%
BCOMF BuyB Communications Ltd$6,175,000
+31.2%
321,431
+33.0%
0.76%
-34.2%
MDAS NewMEDA AB-A SHS$6,103,000–433,889
+100.0%
0.75%–
SGEN SellSEATTLE GENETICS INC$5,776,000
-49.3%
155,360
-47.8%
0.71%
-74.6%
DYAX SellDYAX CORP$5,238,000
-16.1%
517,556
-20.4%
0.65%
-57.9%
NewApple Inc$5,042,000–50,045
+100.0%
0.62%–
ITRN NewIturan Location and Control Lt$4,861,000–231,115
+100.0%
0.60%–
AMAG NewAMAG PHARMACEUTICALS INC$4,794,000–150,230
+100.0%
0.59%–
CLVS SellCLOVIS ONCOLOGY INC$4,625,000
+6.4%
101,955
-2.9%
0.57%
-46.7%
PCYC SellPHARMACYCLICS INC$4,561,000
+1.7%
38,840
-22.3%
0.56%
-49.1%
CSX SellCSX Corp$4,478,000
-2.0%
139,675
-5.8%
0.55%
-50.9%
GSK SellGLAXOSMITHKLINE PLC-SPON ADRsponsored adr$4,464,000
-72.2%
97,100
-67.6%
0.55%
-86.1%
MYL NewMYLAN INC$4,417,000–97,100
+100.0%
0.55%–
ASPX NewAUSPEX PHARMACEUTICALS INC$4,237,000–165,074
+100.0%
0.52%–
BRCM BuyBroadcom Corpcl a$4,016,000
+36.7%
99,360
+25.6%
0.50%
-31.5%
AGTC NewAPPLIED GENETIC TECHNOLOGIES$3,922,000–210,724
+100.0%
0.48%–
P103PS BuyNPS PHARMACEUTICALS INC$3,625,000
+123.9%
139,420
+184.5%
0.45%
+12.3%
UNP NewUnion Pacific Corp$3,503,000–32,312
+100.0%
0.43%–
TKAI NewTOKAI PHARMACEUTICALS INC$3,482,000–230,000
+100.0%
0.43%–
ICPT NewINTERCEPT PHARMACEUTICALS IN$3,447,000–14,565
+100.0%
0.43%–
PRQR NewPROQR THERAPEUTICS NV$3,438,000–200,000
+100.0%
0.42%–
AERI BuyAERIE PHARMACEUTICALS INC$3,383,000
+24.1%
163,516
+48.7%
0.42%
-37.8%
CBAY NewCYMABAY THERAPEUTICS INC$3,354,000–490,355
+100.0%
0.41%–
CVS BuyCVS Caremark Corp$3,168,000
+117.9%
39,810
+106.3%
0.39%
+9.2%
VFC NewVF Corp$3,163,000–47,900
+100.0%
0.39%–
RDUS NewRADIUS HEALTH INC$3,150,000–150,000
+100.0%
0.39%–
SLXP NewSALIX PHARMACEUTICALS LTD$3,125,000–20,000
+100.0%
0.39%–
XLV BuyHealth Care Select Sector SPDRsbi healthcare$3,122,000
+74.8%
48,853
+66.4%
0.39%
-12.3%
ARRY BuyARRAY BIOPHARMA INC$3,120,000
+140.0%
873,922
+206.6%
0.38%
+20.3%
XLRN NewACCELERON PHARMA INC$3,024,000–100,000
+100.0%
0.37%–
INCY SellINCYTE CORP$3,001,000
-27.2%
61,173
-16.2%
0.37%
-63.4%
AVNR SellAVANIR PHARMACEUTICALS INC-Acl a new$2,980,000
-47.2%
250,000
-75.0%
0.37%
-73.5%
BuyTJX Cos Inccall$2,959,000
+4188.4%
50,000
+9900.0%
0.37%
+2052.9%
SLB NewSchlumberger Ltd$2,928,000–28,790
+100.0%
0.36%–
YUM SellYum! Brands Inc$2,873,000
-37.3%
39,910
-29.3%
0.36%
-68.6%
PTCT SellPTC THERAPEUTICS INC$2,800,000
-28.6%
63,625
-57.6%
0.35%
-64.2%
TW SellTowers Watson & Cocl a$2,786,000
-36.0%
28,000
-32.9%
0.34%
-67.9%
SAGE NewSAGE THERAPEUTICS INC$2,770,000–87,924
+100.0%
0.34%–
OTIC NewOTONOMY INC$2,666,000–111,085
+100.0%
0.33%–
NICE NewNICE Systems Ltdsponsored adr$2,622,000–64,542
+100.0%
0.32%–
GOOG  Google Inccl c$2,621,000
+0.3%
4,5400.0%0.32%
-49.7%
CL SellColgate-Palmolive Co$2,615,000
-19.8%
40,099
-16.1%
0.32%
-59.8%
IRWD NewIRONWOOD PHARMACEUTICALS INC$2,516,000–194,200
+100.0%
0.31%–
CPRX NewCATALYST PHARMACEUTICAL PART$2,276,000–685,500
+100.0%
0.28%–
VNDA BuyVANDA PHARMACEUTICALS INC$2,267,000
+0.1%
218,390
+56.0%
0.28%
-49.8%
MGNX SellMACROGENICS INC$2,253,000
-6.6%
107,781
-2.9%
0.28%
-53.2%
GOOGL  Google Inccl a$2,227,000
+0.7%
3,7840.0%0.28%
-49.5%
LJPC NewLA JOLLA PHARMACEUTICAL CO$2,146,000–223,330
+100.0%
0.26%–
TRVN SellTREVENA INC$2,126,000
+10.3%
331,111
-2.9%
0.26%
-44.6%
NewARENA PHARMACEUTICALS INC$2,095,000–500,000
+100.0%
0.26%–
RLYP NewRELYPSA INC$2,048,000–97,100
+100.0%
0.25%–
AKBA BuyAKEBIA THERAPEUTICS INC$1,988,000
-1.3%
89,817
+23.9%
0.25%
-50.5%
IMMU SellIMMUNOMEDICS INC$1,987,000
-1.0%
534,050
-2.9%
0.24%
-50.5%
SNA NewSnap-on Inc$1,949,000–16,100
+100.0%
0.24%–
ATNM SellACTINIUM PHARMACEUTICALS INC$1,952,000
-9.9%
291,300
-2.9%
0.24%
-54.9%
CLDN BuyCELLADON CORP$1,942,000
-19.2%
185,656
+23.8%
0.24%
-59.5%
KITE NewKITE PHARMA INC$1,937,000–67,970
+100.0%
0.24%–
MA NewMasterCard Inccl a$1,922,000–26,000
+100.0%
0.24%–
BLUE NewBLUEBIRD BIO INC$1,916,000–53,405
+100.0%
0.24%–
ZFGN NewZAFGEN INC$1,908,000–97,100
+100.0%
0.24%–
MRNS NewMARINUS PHARMACEUTICALS INC$1,899,000–293,533
+100.0%
0.24%–
NewALDER BIOPHARMACEUTICALS INC$1,902,000–150,000
+100.0%
0.24%–
ELLO BuyEllomay Capital Ltd$1,891,000
+884.9%
191,202
+829.8%
0.23%
+397.9%
RNA BuyPROSENSA HOLDING BV$1,849,000
+17.2%
219,345
+75.5%
0.23%
-41.4%
OMED BuyONCOMED PHARMACEUTICALS INC$1,838,000
+5.1%
97,100
+29.5%
0.23%
-47.3%
NewMankind Corpput$1,773,000–300,000
+100.0%
0.22%–
TJX BuyTJX Cos Inc$1,633,000
+18.6%
27,600
+6.5%
0.20%
-40.4%
RXDX SellIGNYTA INC$1,604,000
-13.9%
199,055
-2.9%
0.20%
-56.9%
ACRX NewACELRX PHARMACEUTICALS INC$1,591,000–289,849
+100.0%
0.20%–
OCRX BuyOCERA THERAPEUTICS INC$1,574,000
+62.1%
321,254
+152.9%
0.19%
-18.8%
RCPT SellRECEPTOS INC$1,553,000
-39.2%
25,000
-58.3%
0.19%
-69.5%
EPZM SellEPIZYME INC$1,356,000
-61.5%
50,000
-55.8%
0.17%
-80.6%
CYTK BuyCYTOKINETICS INC$1,279,000
+311.3%
363,212
+457.9%
0.16%
+105.2%
GNVC SellGENVEC INC$1,161,000
-21.4%
558,325
-2.9%
0.14%
-60.7%
EARS NewAURIS MEDICAL AG$1,111,000–191,300
+100.0%
0.14%–
ORPN NewBIO BLAST PHARMA LTD$1,091,000–150,000
+100.0%
0.14%–
PTN NewPALATIN TECHNOLOGIES INC$1,009,000–1,084,466
+100.0%
0.12%–
AFMD NewAFFIMED NV$945,000–150,000
+100.0%
0.12%–
DSCO SellDISCOVERY LABORATORIES INC$893,000
+0.3%
485,500
-2.9%
0.11%
-49.8%
NewALCOBRA LTDcall$866,000–56,100
+100.0%
0.11%–
ONTY SellONCOTHYREON INC$822,000
-65.6%
428,000
-42.0%
0.10%
-82.7%
TLOG SellTETRALOGIC PHARMACEUTICALS C$808,000
-31.4%
194,200
-2.9%
0.10%
-65.5%
ZSPH NewZS PHARMA INC$811,000–20,682
+100.0%
0.10%–
PRTA NewPROTHENA CORP PLC$663,000–29,907
+100.0%
0.08%–
STEM SellSTEMCELLS INC$612,000
-39.7%
485,500
-2.9%
0.08%
-69.6%
KBIO SellKALOBIOS PHARMACEUTICALS INC$542,000
-34.0%
349,560
-2.9%
0.07%
-66.8%
ORA SellOrmat Technologies Inc$522,000
-22.9%
19,889
-15.3%
0.06%
-61.7%
BLRX SellBIOLINERX LTD-SPONS ADRsponsored adr$298,000
-76.1%
193,284
-67.8%
0.04%
-88.0%
CNCE NewCONCERT PHARMACEUTICALS INC$286,000–22,700
+100.0%
0.04%–
BCLI NewBRAINSTORM CELL THERAPEUTICS$265,000–63,331
+100.0%
0.03%–
SMMF BuySUMMIT CORPORATION PLC$63,000
-86.2%
25,000
+3117.5%
0.01%
-92.9%
MCUR NewMACROCURE LTD$51,000–7,100
+100.0%
0.01%–
TTPH SellTETRAPHASE PHARMACEUTICALS I$47,000
-98.2%
2,365
-98.8%
0.01%
-99.1%
AUXL NewAUXILIUM PHARMACEUTICALS INC$30,000–1,000
+100.0%
0.00%–
AGIO SellAGIOS PHARMACEUTICALS INC$25,000
-97.8%
405
-98.4%
0.00%
-98.9%
LMNS ExitLumenis Ltd$0–-245
-100.0%
0.00%–
ExitVertex Pharmaceuticals Incput$0–-1,500
-100.0%
-0.00%–
ExitAuxilium Pharmaceuticals Inccall$0–-935
-100.0%
-0.01%–
TISA ExitTOP Image Systems Ltdord$0–-20,000
-100.0%
-0.02%–
ExitTeva Pharmaceutical Industriesput$0–-1,000
-100.0%
-0.02%–
ExitInsmed Inccall$0–-1,000
-100.0%
-0.07%–
ExitSPDR S&P 500 ETF Trustcall$0–-1,500
-100.0%
-0.08%–
RXII ExitRXi Pharmaceuticals Corp$0–-175,815
-100.0%
-0.13%–
CORI ExitCorium International Inc$0–-69,100
-100.0%
-0.13%–
ExitImpax Laboratories Inccall$0–-1,000
-100.0%
-0.14%–
TGTX ExitTG Therapeutics Inc$0–-60,000
-100.0%
-0.14%–
DPRX ExitDipexium Pharmaceuticals Inc$0–-94,400
-100.0%
-0.23%–
ExitAmgen Inccall$0–-1,238
-100.0%
-0.28%–
ACHN ExitAchillion Pharmaceuticals Inc$0–-150,000
-100.0%
-0.28%–
SAH ExitSonic Automotive Inccl a$0–-50,000
-100.0%
-0.33%–
ExitArrowhead Research Corp$0–-100,000
-100.0%
-0.35%–
PAG ExitPenske Automotive Group Inc$0–-29,327
-100.0%
-0.36%–
INSM ExitInsmed Inc$0–-79,400
-100.0%
-0.39%–
ITCI ExitIntra-Cellular Therapies Inc$0–-94,300
-100.0%
-0.39%–
GLMD ExitGalmed Pharmaceuticals Ltd$0–-170,000
-100.0%
-0.41%–
CYTR ExitCytRx Corp$0–-400,000
-100.0%
-0.41%–
AQXP ExitAquinox Pharmaceuticals Inc$0–-190,000
-100.0%
-0.44%–
ExitVertex Pharmaceuticals Inccall$0–-1,000
-100.0%
-0.47%–
AMBI ExitAmbit Biosciences Corp$0–-277,568
-100.0%
-0.47%–
PCLN Exitpriceline.com Inc$0–-1,932
-100.0%
-0.57%–
AMPE ExitAmpio Pharmaceuticals Inc$0–-312,000
-100.0%
-0.64%–
CSTE ExitCaesarstone Sdot-Yam Ltd$0–-59,600
-100.0%
-0.72%–
AN ExitAutoNation Inc$0–-52,600
-100.0%
-0.77%–
GILD ExitGilead Sciences Inc$0–-50,000
-100.0%
-1.02%–
WAG ExitWalgreen Co$0–-60,993
-100.0%
-1.11%–
BIIB ExitBiogen Idec Inc$0–-22,000
-100.0%
-1.71%–
SNY ExitSanofisponsored adr$0–-120,000
-100.0%
-3.14%–
Other managers

Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):

Original filings

The following EDGAR filing(s) were analyzed to create this report:

  • View 13F-HR/A filed 2014-11-20
Signatures

The EDGAR filing(s) were signed by:

Top long-term holdings
NameQuarters ownedLatest quarter ownedMax weighting
TEVA PHARMACEUTICAL-SP ADR36Q3 20238.4%
MERCK & CO INC NEW35Q3 20238.4%
NICE Systems Ltd27Q3 20234.4%
BIOGEN INC26Q3 20236.7%
AMICUS THERAPEUTICS INC26Q2 20224.3%
PFIZER INC25Q3 20239.2%
SAREPTA THERAPEUTICS INC25Q3 20233.2%
JOHNSON & JOHNSON24Q3 20238.0%
UNIQURE NV23Q3 20231.2%
SYNDAX PHARMACEUTICALS INC22Q3 20233.9%

View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.

Latest significant ownerships (13-D/G)
SPHERA FUNDS MANAGEMENT LTD. Q3 2014 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
FiledShares Percentage
Cyclacel Pharmaceuticals, Inc.February 06, 2023250,0002.0%
Altimmune, Inc.February 14, 20221,244,2413.1%
Allot Ltd.February 16, 20211,129,0543.2%
Larimar Therapeutics, Inc.February 16, 2021? ?
Neos Therapeutics, Inc.February 16, 2021? ?
Orgenesis Inc.February 16, 2021525,2160.0%
Sio Gene Therapies Inc.February 16, 2021? ?
X4 Pharmaceuticals, IncFebruary 16, 2021250,0000.0%
Axovant Gene Therapies Ltd.February 25, 20202,931,0178.0%
Axovant Gene Therapies Ltd.February 11, 2020398,5401.8%

View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.

Latest filings
TypeFiled
13F-HR/A2024-02-15
13F-HR2024-02-14
SC 13G2024-02-08
SC 13G/A2024-02-05
SC 13G/A2024-02-05
SC 13G/A2024-02-05
SC 13G/A2024-02-05
13F-HR2023-11-14
SC 13G2023-10-10
SC 13G2023-08-30

View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.

All filings

View complete filings history.

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Issues

The following issues were detected while analyzing the report:

  • The reported total value is incorrect (809455000.0 != 809459000.0)
  • The reported has been restated
  • The reported has been amended

Export SPHERA FUNDS MANAGEMENT LTD.'s holdings

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