$6.63 Billion is the total value of RTW INVESTMENTS, LP's 120 reported holdings in Q3 2021. The portfolio turnover from Q2 2021 to Q3 2021 was 29.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RCKT | Buy | ROCKET PHARMACEUTICALS INC | $469,601,000 | -29.3% | 15,802,802 | +5.4% | 7.08% | -29.3% |
| SPY | Sell | SPDR S&P 500 ETF TRtr unit | $374,749,000 | -12.1% | 873,255 | -12.3% | 5.65% | -12.2% |
| ALNY | ALNYLAM PHARMACEUTICALS INC | $317,836,000 | +11.4% | 1,683,362 | 0.0% | 4.79% | +11.3% | |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $264,044,000 | +12.2% | 1,492,532 | +2.4% | 3.98% | +12.1% |
| TMO | New | THERMO FISHER SCIENTIFIC INC | $237,673,000 | – | 416,000 | +100.0% | 3.58% | – |
| MASI | Buy | MASIMO CORP | $225,377,000 | +12.5% | 832,540 | +0.8% | 3.40% | +12.4% |
| VCEL | VERICEL CORP | $220,457,000 | -7.0% | 4,517,570 | 0.0% | 3.32% | -7.1% | |
| CLDX | CELLDEX THERAPEUTICS INC NEW | $211,044,000 | +61.5% | 3,908,947 | 0.0% | 3.18% | +61.4% | |
| NTRA | Buy | NATERA INC | $207,527,000 | +6.8% | 1,862,234 | +8.8% | 3.13% | +6.7% |
| PTCT | PTC THERAPEUTICS INC | $196,988,000 | -12.0% | 5,293,966 | 0.0% | 2.97% | -12.0% | |
| ILMN | ILLUMINA INC | $195,825,000 | -14.3% | 482,791 | 0.0% | 2.95% | -14.3% | |
| ESTA | ESTABLISHMENT LABS HLDGS INC | $166,004,000 | -18.0% | 2,319,138 | 0.0% | 2.50% | -18.1% | |
| DRNA | Buy | DICERNA PHARMACEUTICALS INC | $152,861,000 | -45.5% | 7,582,396 | +0.8% | 2.30% | -45.6% |
| TNDM | Buy | TANDEM DIABETES CARE INC | $138,568,000 | +24.0% | 1,160,734 | +1.2% | 2.09% | +24.0% |
| GMED | GLOBUS MED INCcl a | $128,018,000 | -1.2% | 1,670,811 | 0.0% | 1.93% | -1.2% | |
| AXNX | AXONICS INC | $126,526,000 | +2.6% | 1,943,864 | 0.0% | 1.91% | +2.6% | |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $118,101,000 | +19.6% | 4,795,000 | +20.0% | 1.78% | +19.5% |
| GH | Buy | GUARDANT HEALTH INC | $115,677,000 | +1.4% | 925,342 | +0.8% | 1.74% | +1.4% |
| CCCC | Buy | C4 THERAPEUTICS INC | $111,475,000 | +37.1% | 2,494,965 | +16.1% | 1.68% | +37.0% |
| ISEE | IVERIC BIO INC | $109,175,000 | +157.4% | 6,722,624 | 0.0% | 1.65% | +157.2% | |
| FULC | Buy | FULCRUM THERAPEUTICS INC | $108,758,000 | +223.8% | 3,855,291 | +20.3% | 1.64% | +223.5% |
| TXG | 10X GENOMICS INC | $106,926,000 | -25.7% | 734,481 | 0.0% | 1.61% | -25.7% | |
| PEN | New | PENUMBRA INC | $102,654,000 | – | 385,194 | +100.0% | 1.55% | – |
| DERMTECH INC | $100,140,000 | -22.8% | 3,118,665 | 0.0% | 1.51% | -22.8% | ||
| STOK | STOKE THERAPEUTICS INC | $92,710,000 | -24.4% | 3,644,248 | 0.0% | 1.40% | -24.5% | |
| IDYA | IDEAYA BIOSCIENCES INC | $83,257,000 | +21.4% | 3,266,255 | 0.0% | 1.26% | +21.4% | |
| MGNX | Buy | MACROGENICS INC | $83,248,000 | +21.7% | 3,975,554 | +56.1% | 1.26% | +21.6% |
| RGNX | Buy | REGENXBIO INC | $77,358,000 | +13.3% | 1,845,366 | +5.0% | 1.17% | +13.3% |
| RXDX | PROMETHEUS BIOSCIENCES INC | $77,390,000 | +1.8% | 3,264,031 | 0.0% | 1.17% | +1.7% | |
| CYTK | CYTOKINETICS INC | $71,480,000 | +80.6% | 2,000,000 | 0.0% | 1.08% | +80.6% | |
| ITOS | Buy | ITEOS THERAPEUTICS INC | $63,531,000 | +44.3% | 2,353,015 | +37.1% | 0.96% | +44.3% |
| LABP | LANDOS BIOPHARMA INC | $62,426,000 | +28.8% | 4,275,722 | 0.0% | 0.94% | +28.7% | |
| CUTR | Buy | CUTERA INC | $58,616,000 | +65.9% | 1,257,862 | +74.5% | 0.88% | +65.9% |
| AVDL | AVADEL PHARMACEUTICALS PLCsponsored adr | $56,271,000 | +45.6% | 5,741,939 | 0.0% | 0.85% | +45.6% | |
| PRQR | PROQR THRAPEUTICS N V | $53,929,000 | +24.2% | 6,443,113 | 0.0% | 0.81% | +24.1% | |
| AXSM | AXSOME THERAPEUTICS INC | $53,280,000 | -51.1% | 1,616,497 | 0.0% | 0.80% | -51.2% | |
| New | TENAYA THERAPEUTICS INC | $48,581,000 | – | 2,458,750 | +100.0% | 0.73% | – | |
| AGEN | Sell | AGENUS INC | $47,641,000 | -24.1% | 9,074,438 | -20.7% | 0.72% | -24.2% |
| APYX | Buy | APYX MEDICAL CORPORATION | $47,066,000 | +34.6% | 3,398,279 | +0.2% | 0.71% | +34.5% |
| IMCR | IMMUNOCORE HLDGS PLCads | $46,172,000 | -3.6% | 1,245,532 | 0.0% | 0.70% | -3.7% | |
| GHRS | GH RESEARCH PLCordinary shares | $45,719,000 | +7.2% | 2,168,957 | 0.0% | 0.69% | +7.0% | |
| OM | Buy | OUTSET MED INC | $44,232,000 | +20.1% | 894,652 | +21.4% | 0.67% | +20.0% |
| TARS | TARSUS PHARMACEUTICALS INC | $43,393,000 | -25.6% | 2,013,601 | 0.0% | 0.65% | -25.8% | |
| ARGX | Buy | ARGENX SEsponsored adr | $42,374,000 | +343.2% | 140,311 | +341.9% | 0.64% | +343.8% |
| LUNG | Buy | PULMONX CORP | $41,902,000 | -15.9% | 1,164,600 | +3.1% | 0.63% | -16.0% |
| RLMD | RELMADA THERAPEUTICS INC | $40,312,000 | -18.1% | 1,538,026 | 0.0% | 0.61% | -18.2% | |
| CSTL | Sell | CASTLE BIOSCIENCES INC | $39,834,000 | -32.0% | 599,009 | -25.0% | 0.60% | -32.0% |
| NSTG | NANOSTRING TECHNOLOGIES INC | $38,601,000 | -25.9% | 804,029 | 0.0% | 0.58% | -26.0% | |
| OLK | Buy | OLINK HLDG ABsponsored ads | $31,966,000 | -25.6% | 1,318,188 | +5.6% | 0.48% | -25.6% |
| PTGX | Sell | PROTAGONIST THERAPEUTICS INC | $31,075,000 | -80.3% | 1,753,695 | -50.0% | 0.47% | -80.3% |
| BLU | BELLUS HEALTH INC NEW | $30,431,000 | +97.1% | 4,968,017 | 0.0% | 0.46% | +97.0% | |
| New | SIGHT SCIENCES INC | $29,144,000 | – | 1,283,871 | +100.0% | 0.44% | – | |
| JNJ | JOHNSON & JOHNSON | $27,543,000 | -2.0% | 170,542 | 0.0% | 0.42% | -2.1% | |
| GLUE | MONTE ROSA THERAPEUTICS INC | $26,005,000 | +3.1% | 1,214,572 | 0.0% | 0.39% | +2.9% | |
| CLSD | CLEARSIDE BIOMEDICAL INC | $25,241,000 | +23.2% | 4,206,765 | 0.0% | 0.38% | +23.3% | |
| MIST | MILESTONE PHARMACEUTICALS IN | $24,639,000 | +3.8% | 4,315,102 | 0.0% | 0.37% | +3.9% | |
| PMVP | Buy | PMV PHARMACEUTICALS INC | $24,134,000 | +45.9% | 809,863 | +67.3% | 0.36% | +45.6% |
| GTH | Sell | GENETRON HLDGS LTDads | $23,156,000 | -36.8% | 1,671,894 | -8.0% | 0.35% | -36.9% |
| OYST | OYSTER PT PHARMA INC | $22,055,000 | -31.1% | 1,861,209 | 0.0% | 0.33% | -31.1% | |
| New | AADI BIOSCIENCES INC | $21,336,000 | – | 764,701 | +100.0% | 0.32% | – | |
| EPIX | Sell | ESSA PHARMA INC | $21,098,000 | -75.8% | 2,637,192 | -13.6% | 0.32% | -75.9% |
| ABUS | Sell | ARBUTUS BIOPHARMA CORP | $20,306,000 | +12.1% | 4,733,323 | -20.8% | 0.31% | +12.1% |
| INMD | INMODE LTD | $19,931,000 | +68.4% | 124,999 | 0.0% | 0.30% | +68.2% | |
| CERE | Buy | CEREVEL THERAPEUTICS HLDNG I | $19,667,000 | +53.5% | 666,666 | +33.3% | 0.30% | +53.9% |
| New | RENOVACOR INC | $19,254,000 | – | 2,187,540 | +100.0% | 0.29% | – | |
| TELA | Sell | TELA BIO INC | $19,010,000 | -15.3% | 1,391,619 | -0.1% | 0.29% | -15.1% |
| ATHA | ATHIRA PHARMA INC | $17,884,000 | -8.4% | 1,906,557 | 0.0% | 0.27% | -8.5% | |
| ADVM | Buy | ADVERUM BIOTECHNOLOGIES INC | $16,240,000 | -36.9% | 7,483,757 | +1.7% | 0.24% | -37.0% |
| NEO | NEOGENOMICS INC | $14,873,000 | +13.2% | 311,111 | 0.0% | 0.22% | +13.1% | |
| URGN | New | UROGEN PHARMA LTD | $14,423,000 | – | 857,464 | +100.0% | 0.22% | – |
| OSUR | New | ORASURE TECHNOLOGIES INC | $13,286,000 | – | 1,174,722 | +100.0% | 0.20% | – |
| BWAY | Buy | BRAINSWAY LTDsponsored ads | $12,915,000 | -21.0% | 1,602,381 | +0.0% | 0.20% | -21.1% |
| VINC | VINCERX PHARMA INC | $12,127,000 | +24.5% | 749,999 | 0.0% | 0.18% | +24.5% | |
| IMUX | Buy | IMMUNIC INC | $12,132,000 | +7.5% | 1,370,814 | +48.9% | 0.18% | +7.6% |
| XGN | EXAGEN INC | $11,171,000 | -9.3% | 821,414 | 0.0% | 0.17% | -9.7% | |
| CNTB | CONNECT BIOPHARMA HLDGS LTDads | $10,904,000 | +24.1% | 450,000 | 0.0% | 0.16% | +23.3% | |
| JNCE | New | JOUNCE THERAPEUTICS INC | $10,374,000 | – | 1,396,203 | +100.0% | 0.16% | – |
| New | NYXOAH S A | $10,087,000 | – | 344,911 | +100.0% | 0.15% | – | |
| BMEA | BIOMEA FUSION INC | $9,877,000 | -19.5% | 830,794 | 0.0% | 0.15% | -19.5% | |
| LSAQ | LIFESCI ACQUISITION II CORP | $9,555,000 | -2.0% | 975,000 | 0.0% | 0.14% | -2.0% | |
| LJPC | LA JOLLA PHARMACEUTICAL CO | $9,288,000 | -6.8% | 2,327,903 | 0.0% | 0.14% | -6.7% | |
| New | TANGO THERAPEUTICS INC | $7,758,000 | – | 600,000 | +100.0% | 0.12% | – | |
| New | PROCEPT BIOROBOTICS CORP | $7,406,000 | – | 194,136 | +100.0% | 0.11% | – | |
| HLXA | HELIX ACQUISITION CORP | $7,388,000 | -4.8% | 750,000 | 0.0% | 0.11% | -5.1% | |
| CTMX | CYTOMX THERAPEUTICS INC | $7,131,000 | -19.6% | 1,400,939 | 0.0% | 0.11% | -19.4% | |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | $6,588,000 | -36.6% | 1,100,000 | 0.0% | 0.10% | -36.9% | |
| RACB | RESEARCH ALLIANCE CORP II | $6,274,000 | -2.9% | 637,000 | 0.0% | 0.10% | -2.1% | |
| BLSA | BCLS ACQUISITION CORP | $6,101,000 | -5.4% | 612,500 | 0.0% | 0.09% | -5.2% | |
| ASLN | ASLAN PHARMACEUTICALS LTDads | $5,785,000 | -46.1% | 3,250,000 | 0.0% | 0.09% | -46.3% | |
| SRRK | SCHOLAR ROCK HLDG CORP | $5,336,000 | +14.2% | 161,612 | 0.0% | 0.08% | +14.3% | |
| New | SOPHIA GENETICS SAordinary shares | $5,259,000 | – | 300,000 | +100.0% | 0.08% | – | |
| BLI | BERKELEY LTS INC | $5,038,000 | -56.3% | 257,546 | 0.0% | 0.08% | -56.3% | |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $5,025,000 | -6.2% | 500,000 | 0.0% | 0.08% | -6.2% | |
| SMIHU | SUMMIT HEALTHCRE ACQUISTN COunit 06/03/2026 | $5,025,000 | +0.4% | 500,000 | 0.0% | 0.08% | 0.0% | |
| RCEL | AVITA MEDICAL INC | $4,962,000 | -13.6% | 280,000 | 0.0% | 0.08% | -13.8% | |
| New | ARYA SCIENCES ACQUISITN CORP | $4,940,000 | – | 500,000 | +100.0% | 0.07% | – | |
| IMTX | IMMATICS N.V | $4,550,000 | +12.0% | 350,000 | 0.0% | 0.07% | +13.1% | |
| AFIB | Buy | ACUTUS MED INC | $4,348,000 | -43.3% | 491,834 | +8.9% | 0.07% | -43.1% |
| APVO | APTEVO THERAPEUTICS INC | $4,345,000 | -31.2% | 281,402 | 0.0% | 0.07% | -30.5% | |
| FVAM | 5 01 ACQUISITION CORP | $3,849,000 | -1.5% | 392,000 | 0.0% | 0.06% | -1.7% | |
| PNT | New | POINT BIOPHARMA GLOBAL INC | $3,768,000 | – | 490,000 | +100.0% | 0.06% | – |
| New | MAXCYTE INC | $3,358,000 | – | 275,000 | +100.0% | 0.05% | – | |
| MAAC | New | MONTES ARCHIMEDES ACQUISITIO | $3,160,000 | – | 400,000 | +100.0% | 0.05% | – |
| MSAC | MEDICUS SCIENCES ACQUISITION | $2,925,000 | +1.0% | 300,000 | 0.0% | 0.04% | 0.0% | |
| New | SEMA4 HOLDINGS CORP | $2,936,000 | – | 400,000 | +100.0% | 0.04% | – | |
| CVRX | CVRX INC | $2,481,000 | -40.9% | 150,000 | 0.0% | 0.04% | -41.3% | |
| DNAY | CODEX DNA INC | $2,226,000 | -49.4% | 200,000 | 0.0% | 0.03% | -48.5% | |
| TWST | TWIST BIOSCIENCE CORP | $1,976,000 | -19.7% | 18,473 | 0.0% | 0.03% | -18.9% | |
| MIRO | MIROMATRIX MED INC | $1,949,000 | -40.3% | 280,000 | 0.0% | 0.03% | -40.8% | |
| New | RXSIGHT INC | $1,901,000 | – | 150,000 | +100.0% | 0.03% | – | |
| PROF | PROFOUND MED CORP | $1,788,000 | -10.5% | 122,098 | 0.0% | 0.03% | -10.0% | |
| MDXG | Sell | MIMEDX GROUP INC | $1,792,000 | -94.7% | 295,748 | -89.0% | 0.03% | -94.7% |
| BOLT | BOLT BIOTHERAPEUTICS INC | $1,599,000 | -18.2% | 126,365 | 0.0% | 0.02% | -17.2% | |
| AKYA | AKOYA BIOSCIENCES INC | $1,396,000 | -27.8% | 100,000 | 0.0% | 0.02% | -27.6% | |
| MASS | 908 DEVICES INC | $1,301,000 | -16.1% | 40,000 | 0.0% | 0.02% | -13.0% | |
| OMIC | SINGULAR GENOMICS SYSTEMS IN | $1,119,000 | -59.3% | 100,000 | 0.0% | 0.02% | -58.5% | |
| ZY | ZYMERGEN INC | $922,000 | -67.1% | 70,000 | 0.0% | 0.01% | -66.7% | |
| BNR | BURNING ROCK BIOTECH LTDsponsored ads | $536,000 | -39.4% | 30,000 | 0.0% | 0.01% | -38.5% | |
| New | RENOVACOR INC*w exp 99/99/999 | $224,000 | – | 350,000 | +100.0% | 0.00% | – | |
| MSACW | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $24,000 | -29.4% | 33,331 | 0.0% | 0.00% | -100.0% | |
| PROG | Exit | PROGENITY INC | $0 | – | -100,000 | -100.0% | -0.01% | – |
| AZYO | Exit | AZIYO BIOLOGICS INC | $0 | – | -125,000 | -100.0% | -0.02% | – |
| BDSX | Exit | BIODESIX INC | $0 | – | -125,000 | -100.0% | -0.02% | – |
| CEREW | Exit | CEREVEL THERAPEUTICS HLDNG I*w exp 06/09/202 | $0 | – | -166,666 | -100.0% | -0.04% | – |
| MRVI | Exit | MARAVAI LIFESCIENCES HLDGS I | $0 | – | -70,000 | -100.0% | -0.04% | – |
| PSNL | Exit | PERSONALIS INC | $0 | – | -127,501 | -100.0% | -0.05% | – |
| CHAQU | Exit | CHARDAN HEALTHCR ACQSTN 2 COunit 99/99/9999 | $0 | – | -350,000 | -100.0% | -0.06% | – |
| RACA | Exit | THERAPEUTICS ACQUISITION COR | $0 | – | -490,000 | -100.0% | -0.08% | – |
| ITMR | Exit | ITAMAR MED LTDsponsored ads | $0 | – | -268,609 | -100.0% | -0.10% | – |
| BCTG | Exit | BCTG ACQUISITION CORP | $0 | – | -600,000 | -100.0% | -0.10% | – |
| CHAQ | Exit | CHARDAN HEALTHCR ACQSTN 2 CO | $0 | – | -837,540 | -100.0% | -0.12% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -2,091,389 | -100.0% | -0.31% | – | |
| QDEL | Exit | QUIDEL CORP | $0 | – | -878,533 | -100.0% | -1.70% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-11-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC | 36 | Q3 2023 | 19.7% |
| MASIMO CORP | 32 | Q3 2023 | 5.8% |
| LA JOLLA PHARMACEUTICAL CO | 31 | Q2 2022 | 9.7% |
| REGENXBIO INC | 30 | Q4 2022 | 10.8% |
| AGENUS INC | 29 | Q2 2022 | 9.0% |
| PTC THERAPEUTICS INC | 28 | Q3 2023 | 12.8% |
| DICERNA PHARMACEUTICALS INC | 28 | Q3 2021 | 10.8% |
| MIRATI THERAPEUTICS INC | 26 | Q3 2023 | 6.2% |
| ARGENX SE | 26 | Q3 2023 | 5.3% |
| VERICEL CORP | 24 | Q3 2023 | 3.9% |
View RTW INVESTMENTS, LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ROCKET PHARMACEUTICALS, INC. | September 19, 2023 | 18,188,457 | - |
| ALLURION TECHNOLOGIES, INC. | August 11, 2023 | 3,457,707 | 7.4% |
| Orchestra BioMed Holdings, Inc. | May 05, 2023 | 5,620,645 | 15.7% |
| Renovacor, Inc.Sold out | April 05, 2023 | 0 | - |
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Aptevo Therapeutics Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ASLAN Pharmaceuticals LtdSold out | February 14, 2023 | 0 | 0.0% |
| Athira Pharma, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| BELLUS Health Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Clearside Biomedical, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
View RTW INVESTMENTS, LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-03-01 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View RTW INVESTMENTS, LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.