$6.41 Billion is the total value of RTW INVESTMENTS, LP's 111 reported holdings in Q1 2021. The portfolio turnover from Q4 2020 to Q1 2021 was 26.5% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RCKT | Sell | Rocket Pharmaceuticals Inc | $697,287,000 | -25.5% | 15,715,286 | -7.9% | 10.88% | -30.7% |
| SPY | New | SPDR S&P 500 ETF TRtr unit | $375,029,000 | – | 946,255 | +100.0% | 5.86% | – |
| VCEL | Vericel Corp | $250,951,000 | +79.9% | 4,517,570 | 0.0% | 3.92% | +67.4% | |
| PTCT | Buy | PTC Therapeutics Inc | $250,669,000 | -2.7% | 5,293,966 | +25.4% | 3.91% | -9.5% |
| ALNY | Buy | Alnylam Pharmaceuticals Inc | $237,674,000 | +8.7% | 1,683,362 | +0.1% | 3.71% | +1.2% |
| MRTX | Buy | Mirati Therapeutics Inc | $228,383,000 | -1.4% | 1,333,232 | +26.4% | 3.56% | -8.2% |
| DRNA | Buy | Dicerna Pharmaceuticals Inc | $190,836,000 | +19.4% | 7,463,291 | +2.9% | 2.98% | +11.1% |
| ILMN | Buy | Illumina Inc | $185,100,000 | +38.3% | 481,956 | +33.2% | 2.89% | +28.7% |
| NTRA | Natera Inc | $173,860,000 | +2.0% | 1,712,234 | 0.0% | 2.71% | -5.1% | |
| Buy | DermTech Inc | $158,397,000 | +69.1% | 3,118,665 | +8.0% | 2.47% | +57.4% | |
| ESTA | Establishment Labs Hldgs Inc | $145,016,000 | +66.1% | 2,319,138 | 0.0% | 2.26% | +54.5% | |
| STOK | Buy | Stoke Therapeutics Inc | $141,543,000 | -35.5% | 3,644,248 | +2.8% | 2.21% | -40.0% |
| MASI | Buy | Masimo Corp | $136,638,000 | +8.5% | 594,956 | +26.7% | 2.13% | +0.9% |
| TXG | Buy | 10x Genomics Inc | $128,784,000 | +37.6% | 711,515 | +7.7% | 2.01% | +28.0% |
| CERN | Buy | Cerner Corp | $127,550,000 | -4.5% | 1,774,485 | +4.3% | 1.99% | -11.2% |
| AXNX | Axonics Modulation Technolog | $112,825,000 | +20.0% | 1,883,864 | 0.0% | 1.76% | +11.6% | |
| QDEL | New | Quidel Corp | $112,391,000 | – | 878,533 | +100.0% | 1.76% | – |
| ARVN | Sell | Arvinas Inc | $107,267,000 | -29.5% | 1,622,799 | -9.4% | 1.68% | -34.4% |
| GMED | Buy | Globus Med Inccl a | $103,039,000 | -3.7% | 1,670,811 | +1.8% | 1.61% | -10.4% |
| IMVT | Sell | Immunovant Inc | $101,962,000 | -70.9% | 6,356,743 | -16.3% | 1.59% | -72.9% |
| TNDM | Buy | Tandem Diabetes Care Inc | $100,537,000 | +59.0% | 1,139,230 | +72.4% | 1.57% | +47.9% |
| ITOS | Buy | Iteos Therapeutics Inc | $94,432,000 | +162.5% | 2,762,791 | +157.2% | 1.47% | +144.0% |
| GH | Buy | Guardant Health Inc | $93,082,000 | +24.1% | 609,774 | +4.8% | 1.45% | +15.5% |
| AXSM | Sell | Axsome Therapeutics Inc | $91,526,000 | -32.8% | 1,616,497 | -3.3% | 1.43% | -37.5% |
| PTGX | Sell | Protagonist Therapeutics Inc | $90,841,000 | +23.5% | 3,507,390 | -3.9% | 1.42% | +14.8% |
| RNA | Avidity Biosciences Inc | $87,131,000 | -14.5% | 3,995,000 | 0.0% | 1.36% | -20.5% | |
| CLDX | Buy | Celldex Therapeutics Inc New | $80,524,000 | +34.3% | 3,908,947 | +14.2% | 1.26% | +25.0% |
| CCCC | C4 Therapeutics Inc | $79,437,000 | +15.7% | 2,149,228 | 0.0% | 1.24% | +7.6% | |
| TARS | Tarsus Pharmaceuticals Inc. | $79,091,000 | -20.1% | 2,463,601 | 0.0% | 1.24% | -25.6% | |
| ADVM | Buy | Adverum Biotechnologies Inc | $72,461,000 | -7.5% | 7,348,976 | +1.7% | 1.13% | -13.9% |
| TBIO | Buy | Translate Bio Inc | $72,262,000 | +31.6% | 4,382,199 | +47.1% | 1.13% | +22.5% |
| MGNX | Buy | MacroGenics Inc | $64,159,000 | +123.4% | 2,014,400 | +60.3% | 1.00% | +107.9% |
| IDYA | Buy | Ideaya Biosciences Inc | $57,957,000 | +124.2% | 2,466,255 | +33.5% | 0.90% | +108.5% |
| CSTL | Castle Biosciences Inc | $54,700,000 | +2.0% | 799,009 | 0.0% | 0.85% | -5.1% | |
| RLMD | Buy | Relmada Therapeutics Inc | $53,897,000 | +11.1% | 1,530,717 | +1.2% | 0.84% | +3.3% |
| NSTG | NanoString Technologies Inc | $52,833,000 | -1.7% | 804,029 | 0.0% | 0.82% | -8.5% | |
| AVDL | Buy | Avadel Pharmaceuticals plcsponsored adr | $51,907,000 | +44.2% | 5,741,939 | +6.6% | 0.81% | +34.1% |
| RXDX | New | Prometheus Biosciences Inc | $51,727,000 | – | 3,264,031 | +100.0% | 0.81% | – |
| LUNG | Pulmonx Corp | $51,668,000 | -31.0% | 1,129,600 | 0.0% | 0.81% | -35.7% | |
| IMCR | New | Immunocore Hldgs PLCads | $50,142,000 | – | 1,245,532 | +100.0% | 0.78% | – |
| ATHA | Sell | Athira Pharma Inc | $48,807,000 | -45.1% | 2,652,553 | -1.2% | 0.76% | -48.9% |
| CYTK | Cytokinetics Inc | $46,520,000 | +12.6% | 2,000,000 | 0.0% | 0.73% | +4.8% | |
| PRQR | Buy | ProQR Thrapeutics N V | $42,463,000 | +101.8% | 6,424,078 | +28.2% | 0.66% | +87.8% |
| ISEE | IVERIC bio Inc | $41,546,000 | -10.6% | 6,722,624 | 0.0% | 0.65% | -16.7% | |
| CRIS | Sell | Curis Inc | $40,973,000 | +34.2% | 3,619,544 | -2.9% | 0.64% | +25.0% |
| GTH | New | Genetron Hldgs Ltdads | $39,018,000 | – | 1,818,162 | +100.0% | 0.61% | – |
| LABP | New | Landos Biopharma Inc | $38,328,000 | – | 4,275,722 | +100.0% | 0.60% | – |
| FULC | Buy | Fulcrum Therapeutics Inc | $37,758,000 | +55.7% | 3,205,291 | +54.7% | 0.59% | +44.7% |
| AGEN | Buy | Agenus Inc | $37,474,000 | -8.4% | 13,777,244 | +7.1% | 0.58% | -14.7% |
| OM | Buy | Outset Med Inc | $37,374,000 | +12.4% | 687,152 | +17.4% | 0.58% | +4.5% |
| OYST | Sell | Oyster Pt Pharma Inc | $34,023,000 | -6.1% | 1,861,209 | -3.3% | 0.53% | -12.7% |
| APYX | Apyx Medical Corporation | $32,760,000 | +34.2% | 3,391,279 | 0.0% | 0.51% | +24.6% | |
| KURA | Sell | Kura Oncology Inc | $30,586,000 | -45.0% | 1,081,912 | -36.4% | 0.48% | -48.9% |
| XGN | Buy | Exagen Inc | $28,461,000 | +72.5% | 1,626,365 | +30.1% | 0.44% | +60.3% |
| JNJ | Buy | Johnson & Johnson | $28,029,000 | +18.9% | 170,542 | +13.9% | 0.44% | +10.9% |
| MDXG | MiMedx Group Inc | $27,813,000 | +13.4% | 2,700,320 | 0.0% | 0.43% | +5.6% | |
| MIST | Milestone Pharmaceuticals In | $24,984,000 | -13.6% | 4,315,102 | 0.0% | 0.39% | -19.6% | |
| Sell | Trillium Therapeutics Inc | $22,462,000 | -29.5% | 2,091,389 | -3.4% | 0.35% | -34.3% | |
| TELA | Sell | Tela Bio Inc | $20,597,000 | -1.0% | 1,382,343 | -0.1% | 0.32% | -7.7% |
| ABUS | Arbutus Biopharma Corp | $19,908,000 | -6.2% | 5,978,355 | 0.0% | 0.31% | -12.6% | |
| BLU | Sell | Bellus Health Inc New | $19,040,000 | +20.7% | 4,968,017 | -4.3% | 0.30% | +12.1% |
| PMVP | Sell | Pmv Pharmaceuticals Inc | $15,923,000 | -48.3% | 484,133 | -3.3% | 0.25% | -51.8% |
| IMUX | Immunic Inc | $14,678,000 | +4.3% | 920,814 | 0.0% | 0.23% | -3.0% | |
| BWAY | Buy | Brainsway Ltdsponsored ads | $14,468,000 | +73.9% | 1,602,181 | +45.2% | 0.23% | +61.4% |
| RGNX | Buy | Regenxbio Inc | $14,209,000 | +11.0% | 416,577 | +47.6% | 0.22% | +3.3% |
| BLI | Sell | Berkeley Lts Inc | $12,937,000 | -55.4% | 257,546 | -20.7% | 0.20% | -58.5% |
| CTMX | Buy | Cytomx Therapeutics Inc | $11,856,000 | +18.5% | 1,533,758 | +0.4% | 0.18% | +10.1% |
| ASLN | New | Aslan Pharmaceuticals Ltdads | $10,888,000 | – | 3,250,000 | +100.0% | 0.17% | – |
| CLSD | Buy | Clearside Biomedical Inc | $10,391,000 | -4.2% | 4,206,765 | +6.3% | 0.16% | -11.0% |
| LJPC | Sell | La Jolla Pharmaceutical Co | $9,870,000 | +6.1% | 2,327,903 | -2.9% | 0.15% | -1.3% |
| VINC | Vincerx Pharma Inc | $9,650,000 | -7.7% | 500,000 | 0.0% | 0.15% | -13.7% | |
| INMD | Inmode Ltd | $9,046,000 | +52.4% | 124,999 | 0.0% | 0.14% | +41.0% | |
| ARGX | argenx SEsponsored adr | $8,744,000 | -6.4% | 31,752 | 0.0% | 0.14% | -12.7% | |
| APVO | Sell | Aptevo Therapeutics Inc | $8,588,000 | -18.7% | 281,402 | -2.4% | 0.13% | -24.3% |
| CHAQ | New | Chardan Healthcr Acqstn 2 Co | $8,417,000 | – | 837,540 | +100.0% | 0.13% | – |
| CNTB | New | Connect Biopharma Holdings Ltdads | $8,325,000 | – | 450,000 | +100.0% | 0.13% | – |
| EPIX | New | Essa Pharma Inc | $8,241,000 | – | 283,692 | +100.0% | 0.13% | – |
| SRRK | Sell | Scholar Rock Holding Corp | $8,187,000 | +1.5% | 161,612 | -2.8% | 0.13% | -5.2% |
| HLXA | Helix Acquisition Corp | $7,658,000 | -10.2% | 750,000 | 0.0% | 0.12% | -16.1% | |
| ARYA | Arya Sciences Acquisition Co | $6,890,000 | +27.0% | 500,000 | 0.0% | 0.11% | +18.7% | |
| CERE | Cerevel Therapeutics Hldng I | $6,865,000 | -17.2% | 500,000 | 0.0% | 0.11% | -23.0% | |
| BCTG | BCTG Acquisition Corp | $6,672,000 | -2.8% | 600,000 | 0.0% | 0.10% | -9.6% | |
| OLK | New | Olink Hldg ABsponsored ads | $6,690,000 | – | 185,838 | +100.0% | 0.10% | – |
| LSAQ | Lifesci Acquisition Ii Corp | $6,591,000 | -5.0% | 650,000 | 0.0% | 0.10% | -11.2% | |
| RACB | New | Research Alliance Corp II | $6,529,000 | – | 637,000 | +100.0% | 0.10% | – |
| BLSA | Bcls Acquisition Corp | $6,474,000 | -5.1% | 612,500 | 0.0% | 0.10% | -11.4% | |
| ITMR | Buy | Itamar Med Ltdsponsored ads | $6,433,000 | +41.7% | 268,609 | +17.5% | 0.10% | +31.6% |
| AFIB | Acutus Med Inc | $6,041,000 | -53.6% | 451,834 | 0.0% | 0.09% | -56.9% | |
| RCEL | New | Avita Medical Inc | $5,550,000 | – | 280,000 | +100.0% | 0.09% | – |
| ARYD | New | Arya Sciences Acqu Corp IVcl a | $5,236,000 | – | 500,000 | +100.0% | 0.08% | – |
| RACA | Therapeutics Acquisition Corp | $5,150,000 | -24.5% | 490,000 | 0.0% | 0.08% | -29.8% | |
| BOLT | New | Bolt Biotherapeutics Inc | $4,937,000 | – | 150,000 | +100.0% | 0.08% | – |
| IMTX | Immatics N.V | $3,924,000 | +3.9% | 350,000 | 0.0% | 0.06% | -3.2% | |
| FVAM | 5 01 Acquisition Corp | $3,900,000 | -2.2% | 392,000 | 0.0% | 0.06% | -9.0% | |
| CHAQU | Chardan Healthcr Acqstn 2 Counit 99/99/9999 | $3,682,000 | -0.7% | 350,000 | 0.0% | 0.06% | -8.1% | |
| NUVB | New | Nuvation Bio Inc | $3,135,000 | – | 300,000 | +100.0% | 0.05% | – |
| PSNL | Personalis Inc | $3,138,000 | -32.8% | 127,501 | 0.0% | 0.05% | -37.2% | |
| MSACU | New | Medicus Sciences Acquisitionunit 99/99/9999 | $2,955,000 | – | 300,000 | +100.0% | 0.05% | – |
| BDSX | Biodesix Inc | $2,539,000 | +0.8% | 125,000 | 0.0% | 0.04% | -4.8% | |
| MRVI | Maravai Lifesciences Hldgs I | $2,495,000 | +27.0% | 70,000 | 0.0% | 0.04% | +18.2% | |
| PROF | Profound Med Corp | $2,459,000 | -2.0% | 122,098 | 0.0% | 0.04% | -9.5% | |
| TWST | Twist Bioscience Corp | $2,288,000 | -12.3% | 18,473 | 0.0% | 0.04% | -18.2% | |
| VINCW | Vincerx Pharma Inc wts $11.5 Exp. 12/24/2025*w exp 12/24/202 | $2,020,000 | +22.4% | 500,000 | 0.0% | 0.03% | +14.3% | |
| MASS | 908 Devices Inc | $1,940,000 | -14.8% | 40,000 | 0.0% | 0.03% | -21.1% | |
| AZYO | Aziyo Biologics Inc | $1,728,000 | +1.4% | 125,000 | 0.0% | 0.03% | -6.9% | |
| BNR | Burning Rock Biotech Ltdsponsored ads | $808,000 | +16.6% | 30,000 | 0.0% | 0.01% | +8.3% | |
| CEREW | Cerevel Therapeutics Hldng I*w exp 06/09/202 | $718,000 | -23.8% | 166,666 | 0.0% | 0.01% | -31.2% | |
| BCAB | Bioatla Inc | $508,000 | +49.4% | 10,000 | 0.0% | 0.01% | +33.3% | |
| PROG | Progenity Inc | $476,000 | -10.4% | 100,000 | 0.0% | 0.01% | -22.2% | |
| NUVBWS | New | Nuvation Bio Inc*w exp 07/07/202 | $267,000 | – | 100,000 | +100.0% | 0.00% | – |
| SEER | Seer Inc | $200,000 | -11.1% | 4,000 | 0.0% | 0.00% | -25.0% | |
| PHGEWS | Exit | BiomX Inc*w exp 10/16/202 | $0 | – | -600,000 | -100.0% | -0.01% | – |
| OSUR | Exit | OraSure Technologies Inc | $0 | – | -184,000 | -100.0% | -0.03% | – |
| PHGE | Exit | Biomx Inc | $0 | – | -600,000 | -100.0% | -0.06% | – |
| PANAU | Exit | Panacea Acquisition Corpunit 99/99/9999 | $0 | – | -300,000 | -100.0% | -0.06% | – |
| GNMK | Exit | GenMark Diagnostics Inc | $0 | – | -762,994 | -100.0% | -0.19% | – |
| ODT | Exit | Odonate Therapeutics Inc | $0 | – | -1,000,139 | -100.0% | -0.32% | – |
| PEN | Exit | Penumbra Inc | $0 | – | -118,273 | -100.0% | -0.35% | – |
| FPRX | Exit | Five Prime Therapeutics Inc | $0 | – | -2,515,788 | -100.0% | -0.72% | – |
| FREQ | Exit | Frequency Therapeutics Inc | $0 | – | -2,461,486 | -100.0% | -1.46% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-05-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC | 36 | Q3 2023 | 19.7% |
| MASIMO CORP | 32 | Q3 2023 | 5.8% |
| LA JOLLA PHARMACEUTICAL CO | 31 | Q2 2022 | 9.7% |
| REGENXBIO INC | 30 | Q4 2022 | 10.8% |
| AGENUS INC | 29 | Q2 2022 | 9.0% |
| PTC THERAPEUTICS INC | 28 | Q3 2023 | 12.8% |
| DICERNA PHARMACEUTICALS INC | 28 | Q3 2021 | 10.8% |
| MIRATI THERAPEUTICS INC | 26 | Q3 2023 | 6.2% |
| ARGENX SE | 26 | Q3 2023 | 5.3% |
| VERICEL CORP | 24 | Q3 2023 | 3.9% |
View RTW INVESTMENTS, LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ROCKET PHARMACEUTICALS, INC. | September 19, 2023 | 18,188,457 | - |
| ALLURION TECHNOLOGIES, INC. | August 11, 2023 | 3,457,707 | 7.4% |
| Orchestra BioMed Holdings, Inc. | May 05, 2023 | 5,620,645 | 15.7% |
| Renovacor, Inc.Sold out | April 05, 2023 | 0 | - |
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Aptevo Therapeutics Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ASLAN Pharmaceuticals LtdSold out | February 14, 2023 | 0 | 0.0% |
| Athira Pharma, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| BELLUS Health Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Clearside Biomedical, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
View RTW INVESTMENTS, LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-03-01 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View RTW INVESTMENTS, LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.