$5.96 Billion is the total value of RTW INVESTMENTS, LP's 102 reported holdings in Q4 2020. The portfolio turnover from Q3 2020 to Q4 2020 was 44.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RCKT | Buy | Rocket Pharmaceuticals Inc | $935,582,000 | +143.4% | 17,060,211 | +1.5% | 15.70% | +69.6% |
| IMVT | Buy | Immunovant Inc | $350,686,000 | +32.7% | 7,592,253 | +1.1% | 5.88% | -7.5% |
| PTCT | Buy | PTC Therapeutics Inc | $257,659,000 | +38.0% | 4,221,836 | +5.7% | 4.32% | -3.8% |
| MRTX | Sell | Mirati Therapeutics Inc | $231,581,000 | +27.2% | 1,054,364 | -3.8% | 3.88% | -11.3% |
| STOK | Stoke Therapeutics Inc | $219,495,000 | +84.9% | 3,544,248 | 0.0% | 3.68% | +28.9% | |
| ALNY | Alnylam Pharmaceuticals Inc | $218,563,000 | -10.7% | 1,681,645 | 0.0% | 3.67% | -37.8% | |
| NTRA | Buy | Natera Inc | $170,402,000 | +37.9% | 1,712,234 | +0.1% | 2.86% | -3.9% |
| DRNA | Buy | Dicerna Pharmaceuticals Inc | $159,802,000 | +22.9% | 7,253,857 | +0.4% | 2.68% | -14.3% |
| ARVN | New | Arvinas Inc | $152,109,000 | – | 1,790,996 | +100.0% | 2.55% | – |
| VCEL | Buy | Vericel Corp | $139,503,000 | +95.5% | 4,517,570 | +17.3% | 2.34% | +36.3% |
| AXSM | Buy | Axsome Therapeutics Inc | $136,252,000 | +14.4% | 1,672,416 | +0.1% | 2.29% | -20.2% |
| ILMN | Buy | Illumina Inc | $133,858,000 | +147.5% | 361,778 | +106.7% | 2.25% | +72.5% |
| CERN | Buy | Cerner Corp | $133,548,000 | +32.7% | 1,701,680 | +22.2% | 2.24% | -7.5% |
| MASI | Buy | Masimo Corp | $125,982,000 | +18.5% | 469,416 | +4.2% | 2.11% | -17.4% |
| GMED | New | Globus Med Inccl a | $107,017,000 | – | 1,640,859 | +100.0% | 1.80% | – |
| RNA | Avidity Biosciences Inc | $101,952,000 | -7.2% | 3,995,000 | 0.0% | 1.71% | -35.3% | |
| TARS | New | Tarsus Pharmaceuticals Inc. | $98,987,000 | – | 2,463,601 | +100.0% | 1.66% | – |
| AXNX | Axonics Modulation Technolog | $94,042,000 | -2.2% | 1,883,864 | 0.0% | 1.58% | -31.8% | |
| DermTech Inc | $93,661,000 | +171.5% | 2,887,215 | 0.0% | 1.57% | +89.0% | ||
| TXG | 10x Genomics Inc | $93,588,000 | +13.6% | 660,933 | 0.0% | 1.57% | -20.9% | |
| ATHA | Buy | Athira Pharma Inc | $88,899,000 | +95.9% | 2,685,779 | +0.6% | 1.49% | +36.6% |
| ESTA | Establishment Labs Hldgs Inc | $87,292,000 | +103.1% | 2,319,138 | 0.0% | 1.46% | +41.5% | |
| FREQ | Frequency Therapeutics Inc | $86,792,000 | +83.6% | 2,461,486 | 0.0% | 1.46% | +27.9% | |
| ADVM | Sell | Adverum Biotechnologies Inc | $78,345,000 | +5.1% | 7,227,364 | -0.1% | 1.31% | -26.8% |
| GH | Buy | Guardant Health Inc | $75,004,000 | +42.9% | 581,970 | +24.0% | 1.26% | -0.5% |
| LUNG | New | Pulmonx Corp | $74,839,000 | – | 1,129,600 | +100.0% | 1.26% | – |
| PTGX | Buy | Protagonist Therapeutics Inc | $73,585,000 | +10.4% | 3,650,069 | +7.1% | 1.24% | -23.1% |
| CCCC | New | C4 Therapeutics Inc | $68,679,000 | – | 2,149,228 | +100.0% | 1.15% | – |
| TNDM | Buy | Tandem Diabetes Care Inc | $63,243,000 | -7.7% | 660,982 | +9.5% | 1.06% | -35.7% |
| CLDX | Buy | Celldex Therapeutics Inc New | $59,968,000 | +29.6% | 3,422,855 | +9.7% | 1.01% | -9.7% |
| KURA | New | Kura Oncology Inc | $55,580,000 | – | 1,701,781 | +100.0% | 0.93% | – |
| TBIO | Sell | Translate Bio Inc | $54,892,000 | +7.7% | 2,978,427 | -20.5% | 0.92% | -24.9% |
| NSTG | Sell | NanoString Technologies Inc | $53,773,000 | +27.0% | 804,029 | -15.1% | 0.90% | -11.5% |
| CSTL | Buy | Castle Biosciences Inc | $53,653,000 | +40.2% | 799,009 | +7.4% | 0.90% | -2.3% |
| RLMD | Buy | Relmada Therapeutics Inc | $48,511,000 | -14.7% | 1,512,673 | +0.1% | 0.81% | -40.5% |
| ISEE | Buy | IVERIC bio Inc | $46,453,000 | +23.6% | 6,722,624 | +0.9% | 0.78% | -13.9% |
| FPRX | New | Five Prime Therapeutics Inc | $42,794,000 | – | 2,515,788 | +100.0% | 0.72% | – |
| CYTK | Cytokinetics Inc | $41,311,000 | +1.5% | 2,000,000 | 0.0% | 0.69% | -29.3% | |
| AGEN | Agenus Inc | $40,910,000 | -20.5% | 12,864,677 | 0.0% | 0.69% | -44.6% | |
| OYST | Buy | Oyster Pt Pharma Inc | $36,240,000 | -10.8% | 1,925,594 | +0.1% | 0.61% | -37.8% |
| ITOS | Buy | Iteos Therapeutics Inc | $35,975,000 | +72.1% | 1,074,166 | +19.0% | 0.60% | +20.1% |
| AVDL | Buy | Avadel Pharmaceuticals plcsponsored adr | $35,989,000 | +33.1% | 5,387,513 | +0.4% | 0.60% | -7.2% |
| OM | Buy | Outset Med Inc | $33,256,000 | +64.2% | 585,074 | +44.5% | 0.56% | +14.3% |
| Buy | Trillium Therapeutics Inc | $31,850,000 | +3.7% | 2,165,197 | +0.2% | 0.53% | -27.7% | |
| PMVP | Buy | Pmv Pharmaceuticals Inc | $30,809,000 | +73.6% | 500,882 | +0.2% | 0.52% | +21.1% |
| CRIS | New | Curis Inc | $30,527,000 | – | 3,727,360 | +100.0% | 0.51% | – |
| BLI | Buy | Berkeley Lts Inc | $29,034,000 | +26.6% | 324,734 | +8.1% | 0.49% | -11.8% |
| MIST | Milestone Pharmaceuticals In | $28,911,000 | -8.5% | 4,315,102 | 0.0% | 0.48% | -36.3% | |
| MGNX | Buy | MacroGenics Inc | $28,722,000 | -9.2% | 1,256,409 | +0.1% | 0.48% | -36.7% |
| IDYA | New | Ideaya Biosciences Inc | $25,856,000 | – | 1,846,843 | +100.0% | 0.43% | – |
| MDXG | MiMedx Group Inc | $24,519,000 | +42.9% | 2,700,320 | 0.0% | 0.41% | -0.5% | |
| APYX | Apyx Medical Corporation | $24,417,000 | +52.9% | 3,391,279 | 0.0% | 0.41% | +6.5% | |
| FULC | Buy | Fulcrum Therapeutics Inc | $24,256,000 | +165.8% | 2,071,409 | +80.0% | 0.41% | +85.0% |
| JNJ | Johnson & Johnson | $23,569,000 | +5.7% | 149,761 | 0.0% | 0.40% | -26.4% | |
| ABUS | Arbutus Biopharma Corp | $21,223,000 | +13.4% | 5,978,355 | 0.0% | 0.36% | -21.1% | |
| PRQR | Buy | ProQR Thrapeutics N V | $21,041,000 | -11.7% | 5,009,768 | +0.7% | 0.35% | -38.5% |
| TELA | Buy | Tela Bio Inc | $20,813,000 | -8.7% | 1,383,816 | +0.4% | 0.35% | -36.4% |
| PEN | New | Penumbra Inc | $20,698,000 | – | 118,273 | +100.0% | 0.35% | – |
| ODT | Buy | Odonate Therapeutics Inc | $19,203,000 | +43.1% | 1,000,139 | +0.1% | 0.32% | -0.3% |
| XGN | Exagen Inc | $16,502,000 | +21.8% | 1,250,131 | 0.0% | 0.28% | -15.0% | |
| BLU | Buy | Bellus Health Inc New | $15,778,000 | +65.3% | 5,189,862 | +23.7% | 0.26% | +15.2% |
| IMUX | Buy | Immunic Inc | $14,079,000 | -16.9% | 920,814 | +0.9% | 0.24% | -42.2% |
| AFIB | Acutus Med Inc | $13,017,000 | -3.3% | 451,834 | 0.0% | 0.22% | -32.7% | |
| RGNX | Sell | Regenxbio Inc | $12,803,000 | +46.1% | 282,260 | -11.4% | 0.22% | +1.9% |
| GNMK | GenMark Diagnostics Inc | $11,140,000 | +2.8% | 762,994 | 0.0% | 0.19% | -28.4% | |
| CLSD | Buy | Clearside Biomedical Inc | $10,845,000 | +78.4% | 3,958,130 | +0.3% | 0.18% | +24.7% |
| APVO | New | Aptevo Therapeutics Inc | $10,564,000 | – | 288,236 | +100.0% | 0.18% | – |
| VINC | New | Vincera Pharma Inc | $10,455,000 | – | 500,000 | +100.0% | 0.18% | – |
| CTMX | Buy | Cytomx Therapeutics Inc | $10,004,000 | -1.4% | 1,527,352 | +0.1% | 0.17% | -31.1% |
| ARGX | argenx SEsponsored adr | $9,338,000 | +12.0% | 31,752 | 0.0% | 0.16% | -21.9% | |
| LJPC | Buy | La Jolla Pharmaceutical Co | $9,302,000 | -3.6% | 2,397,378 | +0.1% | 0.16% | -32.8% |
| HLXA | New | Helix Acquisition Corp | $8,528,000 | – | 750,000 | +100.0% | 0.14% | – |
| BWAY | Sell | Brainsway Ltdsponsored ads | $8,320,000 | +28.8% | 1,103,474 | -0.4% | 0.14% | -10.3% |
| CERE | New | Cerevel Therapeutics Hldng I | $8,290,000 | – | 500,000 | +100.0% | 0.14% | – |
| SRRK | New | Scholar Rock Hldg Corp | $8,065,000 | – | 166,183 | +100.0% | 0.14% | – |
| LSAQ | New | Lifesci Acquisition Ii Corp | $6,936,000 | – | 650,000 | +100.0% | 0.12% | – |
| BCTG | BCTG Acquisition Corp | $6,864,000 | +10.4% | 600,000 | 0.0% | 0.12% | -23.3% | |
| RACA | Therapeutics Acquisition Cor | $6,821,000 | -3.2% | 490,000 | 0.0% | 0.11% | -32.9% | |
| BLSA | New | Bcls Acquisition Corp | $6,823,000 | – | 612,500 | +100.0% | 0.11% | – |
| INMD | Sell | Inmode Ltd | $5,935,000 | -34.4% | 124,999 | -50.0% | 0.10% | -54.1% |
| ARYA | Arya Sciences Acquisition Co | $5,425,000 | +0.3% | 500,000 | 0.0% | 0.09% | -30.0% | |
| PSNL | Sell | Personalis Inc | $4,668,000 | -15.5% | 127,501 | -50.0% | 0.08% | -41.4% |
| ITMR | Sell | Itamar Med Ltdsponsored ads | $4,540,000 | -51.4% | 228,609 | -50.0% | 0.08% | -66.2% |
| FVAM | New | 5 01 Acquisition Corp | $3,987,000 | – | 392,000 | +100.0% | 0.07% | – |
| PANAU | Panacea Acquisition Corpunit 99/99/9999 | $3,828,000 | +6.3% | 300,000 | 0.0% | 0.06% | -26.4% | |
| PHGE | Biomx Inc | $3,828,000 | +0.6% | 600,000 | 0.0% | 0.06% | -30.4% | |
| IMTX | Immatics N.V | $3,777,000 | +1.7% | 350,000 | 0.0% | 0.06% | -29.2% | |
| CHAQU | Chardan Healthcr Acqstn 2 Counit 99/99/9999 | $3,707,000 | +3.3% | 350,000 | 0.0% | 0.06% | -27.9% | |
| TWST | Twist Bioscience Corp | $2,610,000 | +86.0% | 18,473 | 0.0% | 0.04% | +29.4% | |
| BDSX | New | Biodesix Inc | $2,520,000 | – | 125,000 | +100.0% | 0.04% | – |
| PROF | Sell | Profound Med Corp | $2,510,000 | -41.7% | 122,098 | -50.0% | 0.04% | -59.6% |
| MASS | New | 908 Devices Inc | $2,278,000 | – | 40,000 | +100.0% | 0.04% | – |
| MRVI | New | Maravai Lifesciences Hldgs I | $1,964,000 | – | 70,000 | +100.0% | 0.03% | – |
| OSUR | Sell | OraSure Technologies Inc | $1,948,000 | -92.3% | 184,000 | -91.1% | 0.03% | -94.6% |
| AZYO | New | Aziyo Biologics Inc | $1,704,000 | – | 125,000 | +100.0% | 0.03% | – |
| VINCW | New | Vincera Pharma Inc*w exp 12/24/202 | $1,650,000 | – | 500,000 | +100.0% | 0.03% | – |
| CEREW | New | Cerevel Therapeutics Hldng I*w exp 06/09/202 | $942,000 | – | 166,666 | +100.0% | 0.02% | – |
| BNR | Burning Rock Biotech Ltdsponsored ads | $693,000 | -7.8% | 30,000 | 0.0% | 0.01% | -33.3% | |
| PROG | Sell | Progenity Inc | $531,000 | -78.6% | 100,000 | -63.6% | 0.01% | -85.0% |
| PHGEWS | BiomX Inc*w exp 10/16/202 | $480,000 | +12.7% | 600,000 | 0.0% | 0.01% | -20.0% | |
| BCAB | New | Bioatla Inc | $340,000 | – | 10,000 | +100.0% | 0.01% | – |
| SEER | New | Seer Inc | $225,000 | – | 4,000 | +100.0% | 0.00% | – |
| ARYBU | Exit | Arya Sciences Acquisition II Corpunit 06/09/2027 | $0 | – | -500,000 | -100.0% | -0.13% | – |
| EQ | Exit | Equillium Inc | $0 | – | -1,004,784 | -100.0% | -0.14% | – |
| QURE | Exit | Uniqure NV | $0 | – | -158,479 | -100.0% | -0.14% | – |
| LSACU | Exit | Lifesci Acquisition Corpunit 03/31/2025 | $0 | – | -500,000 | -100.0% | -0.16% | – |
| TMDX | Exit | Transmedics Group Inc | $0 | – | -503,266 | -100.0% | -0.17% | – |
| ARCT | Exit | Arcturus Therapeutics Ltd | $0 | – | -251,236 | -100.0% | -0.26% | – |
| AMRS | Exit | Amyris Inc | $0 | – | -5,161,347 | -100.0% | -0.36% | – |
| ALT | Exit | Altimmune Inc | $0 | – | -1,334,940 | -100.0% | -0.42% | – |
| ADAP | Exit | Adaptimmune Therapeutics PLCsponds adr | $0 | – | -2,617,626 | -100.0% | -0.50% | – |
| VXRT | Exit | Vaxart Inc | $0 | – | -3,517,345 | -100.0% | -0.56% | – |
| FIXX | Exit | Homology Medicines Inc | $0 | – | -2,517,906 | -100.0% | -0.65% | – |
| INCY | Exit | Incyte Corp | $0 | – | -334,144 | -100.0% | -0.72% | – |
| BAX | Exit | Baxter International Inc | $0 | – | -1,077,268 | -100.0% | -2.09% | – |
| MYOK | Exit | Myokardia Inc | $0 | – | -936,931 | -100.0% | -3.08% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-02-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC | 36 | Q3 2023 | 19.7% |
| MASIMO CORP | 32 | Q3 2023 | 5.8% |
| LA JOLLA PHARMACEUTICAL CO | 31 | Q2 2022 | 9.7% |
| REGENXBIO INC | 30 | Q4 2022 | 10.8% |
| AGENUS INC | 29 | Q2 2022 | 9.0% |
| PTC THERAPEUTICS INC | 28 | Q3 2023 | 12.8% |
| DICERNA PHARMACEUTICALS INC | 28 | Q3 2021 | 10.8% |
| MIRATI THERAPEUTICS INC | 26 | Q3 2023 | 6.2% |
| ARGENX SE | 26 | Q3 2023 | 5.3% |
| VERICEL CORP | 24 | Q3 2023 | 3.9% |
View RTW INVESTMENTS, LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ROCKET PHARMACEUTICALS, INC. | September 19, 2023 | 18,188,457 | - |
| ALLURION TECHNOLOGIES, INC. | August 11, 2023 | 3,457,707 | 7.4% |
| Orchestra BioMed Holdings, Inc. | May 05, 2023 | 5,620,645 | 15.7% |
| Renovacor, Inc.Sold out | April 05, 2023 | 0 | - |
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Aptevo Therapeutics Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ASLAN Pharmaceuticals LtdSold out | February 14, 2023 | 0 | 0.0% |
| Athira Pharma, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| BELLUS Health Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Clearside Biomedical, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
View RTW INVESTMENTS, LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-03-01 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View RTW INVESTMENTS, LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.