$332 Million is the total value of Sio Capital Management, LLC's 70 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 60.7% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CI | Sell | CIGNA CORP | $27,861,000 | +0.7% | 121,330 | -12.2% | 8.40% | -4.8% |
| MSAC | New | MEDICUS SCIENCES ACQUISITION | $22,580,000 | – | 2,323,000 | +100.0% | 6.81% | – |
| CRIS | Buy | CURIS INC | $18,405,000 | -19.3% | 3,866,645 | +32.7% | 5.55% | -23.7% |
| MRK | Buy | MERCK & CO INC | $17,908,000 | +90.7% | 233,661 | +86.9% | 5.40% | +80.4% |
| CAH | Buy | CARDINAL HEALTH INC | $17,263,000 | +146.8% | 335,271 | +137.1% | 5.20% | +133.4% |
| GLD | Sell | SPDR GOLD TR | $15,368,000 | -8.7% | 89,890 | -12.3% | 4.63% | -13.7% |
| GLPG | Buy | GALAPAGOS NVspon adr | $14,410,000 | +21.9% | 261,377 | +16.3% | 4.34% | +15.3% |
| MCK | Buy | MCKESSON CORP | $14,182,000 | +62.4% | 57,056 | +30.3% | 4.28% | +53.6% |
| ABC | New | AMERISOURCEBERGEN CORP | $12,949,000 | – | 97,440 | +100.0% | 3.90% | – |
| UTHR | Sell | UNITED THERAPEUTICS CORP | $11,494,000 | +5.3% | 53,193 | -10.1% | 3.46% | -0.4% |
| CNC | Sell | CENTENE CORP | $10,364,000 | -7.2% | 125,779 | -29.8% | 3.12% | -12.2% |
| HLF | Buy | HERBALIFE NUTRITION LTD | $9,882,000 | +7.9% | 241,437 | +11.8% | 2.98% | +2.1% |
| IONS | New | IONIS PHARMACEUTICALS INC | $9,816,000 | – | 322,566 | +100.0% | 2.96% | – |
| AVAH | Sell | AVEANNA HEALTHCARE HOLDINGS INC | $7,091,000 | -36.7% | 958,249 | -31.4% | 2.14% | -40.1% |
| ITGR | Buy | INTEGER HOLDINGS CORP | $6,666,000 | +35.9% | 77,881 | +41.9% | 2.01% | +28.6% |
| Sell | RENOVACOR INC | $5,666,000 | -15.0% | 735,908 | -0.1% | 1.71% | -19.6% | |
| OGN | New | ORGANON & CO | $5,410,000 | – | 177,659 | +100.0% | 1.63% | – |
| New | PARDES BIOSCIENCES INC | $5,115,000 | – | 312,438 | +100.0% | 1.54% | – | |
| ALBO | Buy | ALBIREO PHARMA INC | $4,982,000 | -25.2% | 213,913 | +0.2% | 1.50% | -29.3% |
| New | ISOPLEXIS CORP | $4,549,000 | – | 495,012 | +100.0% | 1.37% | – | |
| SNY | New | SANOFI SAsponsored adr | $4,421,000 | – | 88,249 | +100.0% | 1.33% | – |
| MIRM | Buy | MIRUM PHARMACEUTICALS INC | $4,312,000 | -13.1% | 270,314 | +8.6% | 1.30% | -17.8% |
| ARNA | Buy | ARENA PHARMACEUTICALS INC | $3,939,000 | +204.4% | 42,379 | +95.0% | 1.19% | +187.4% |
| VAPO | New | VAPOTHERM INC | $3,728,000 | – | 180,017 | +100.0% | 1.12% | – |
| KZR | New | KEZAR LIFE SCIENCES INC | $3,565,000 | – | 213,247 | +100.0% | 1.08% | – |
| OYST | New | OYSTER POINT PHARMA INC | $3,321,000 | – | 181,857 | +100.0% | 1.00% | – |
| BCYC | New | BICYCLE THERAPEUTICS PLCsponsored ads | $3,287,000 | – | 54,000 | +100.0% | 0.99% | – |
| HZNP | HORIZON THERAPEUTICS PLC | $3,159,000 | -1.7% | 29,319 | 0.0% | 0.95% | -7.0% | |
| VKTX | VIKING THERAPEUTICS INC | $3,040,000 | -26.7% | 660,813 | 0.0% | 0.92% | -30.8% | |
| INGN | New | INOGEN INC | $3,002,000 | – | 88,291 | +100.0% | 0.90% | – |
| SYRS | SYROS PHARMACEUTICALS INC | $2,936,000 | -27.1% | 900,677 | 0.0% | 0.88% | -31.0% | |
| MRUS | New | MERUS NV | $2,862,000 | – | 90,000 | +100.0% | 0.86% | – |
| NTUS | Buy | NATUS MEDICAL INC | $2,556,000 | +159.0% | 107,695 | +173.7% | 0.77% | +144.8% |
| NBSE | NEUBASE THERAPEUTICS INC | $2,547,000 | -22.2% | 906,445 | 0.0% | 0.77% | -26.4% | |
| HSAQ | HEALTH SCIENCES ACQUISITIONS CORP 2 | $2,520,000 | +1.9% | 250,000 | 0.0% | 0.76% | -3.6% | |
| EUCRU | EUCRATES BIOMEDICAL ACQUISITION CORP.unit 10/23/2027 | $2,482,000 | +0.3% | 248,674 | 0.0% | 0.75% | -5.2% | |
| AMED | New | AMEDISYS INC | $2,428,000 | – | 15,000 | +100.0% | 0.73% | – |
| RIGL | RIGEL PHARMACEUTICALS INC | $2,421,000 | -27.0% | 913,621 | 0.0% | 0.73% | -30.9% | |
| AGLE | Buy | AEGLEA BIO THERAPEUTICS INC | $2,368,000 | -33.2% | 498,500 | +11.8% | 0.71% | -36.8% |
| PNT | New | POINT BIOPHARMA GLOBAL INC | $2,115,000 | – | 377,684 | +100.0% | 0.64% | – |
| SRRA | SIERRA ONCOLOGY INC | $2,075,000 | -0.8% | 95,450 | 0.0% | 0.63% | -6.1% | |
| MBRX | MOLECULIN BIOTECH INC | $1,935,000 | -38.0% | 1,040,529 | 0.0% | 0.58% | -41.4% | |
| DTIL | PRECISION BIOSCIENCES INC | $1,903,000 | -35.9% | 257,167 | 0.0% | 0.57% | -39.3% | |
| CBAY | CYMABAY THERAPEUTICS INC | $1,901,000 | -7.4% | 562,339 | 0.0% | 0.57% | -12.4% | |
| ANIP | New | ANI PHARMACEUTICALS INC | $1,843,000 | – | 40,000 | +100.0% | 0.56% | – |
| CYCC | CYCLACEL PHARMACEUTICALS INC | $1,644,000 | -26.2% | 422,598 | 0.0% | 0.50% | -30.1% | |
| ELEV | New | ELEVATION ONCOLOGY INC | $1,505,000 | – | 250,000 | +100.0% | 0.45% | – |
| BLU | New | BELLUS HEALTH INC NEWput | $1,463,000 | – | 181,800 | +100.0% | 0.44% | – |
| LPTX | LEAP THERAPEUTICS INC | $1,426,000 | -19.2% | 440,000 | 0.0% | 0.43% | -23.5% | |
| ASLN | ASLAN PHARMACEUTICALS LTDads | $1,423,000 | -37.1% | 1,270,758 | 0.0% | 0.43% | -40.5% | |
| NEOG | New | NEOGEN CORPput | $1,140,000 | – | 25,100 | +100.0% | 0.34% | – |
| MEIP | MEI PHARMA INC | $1,138,000 | -3.2% | 426,047 | 0.0% | 0.34% | -8.5% | |
| ARDX | Buy | ARDELYX INC | $1,094,000 | +44.9% | 994,604 | +73.9% | 0.33% | +36.9% |
| FUSN | FUSION PHARMACEUTICALS INC | $1,083,000 | -47.4% | 259,763 | 0.0% | 0.33% | -50.3% | |
| VINC | VINCERX PHARMA INC | $1,040,000 | -37.0% | 102,049 | 0.0% | 0.31% | -40.3% | |
| SVRA | New | SAVARA INC | $807,000 | – | 651,170 | +100.0% | 0.24% | – |
| NXTC | New | NEXTCURE INC | $780,000 | – | 130,000 | +100.0% | 0.24% | – |
| CRIS | New | CURIS INCcall | $685,000 | – | 144,000 | +100.0% | 0.21% | – |
| AYLA | Sell | AYALA PHARMACEUTICALS INC | $680,000 | -81.2% | 79,964 | -74.9% | 0.20% | -82.2% |
| SLRX | SALARIUS PHARMACEUTICALS INC | $671,000 | -51.4% | 1,354,291 | 0.0% | 0.20% | -54.1% | |
| XFOR | Sell | X4 PHARMACEUTICALS INC | $634,000 | -85.1% | 276,909 | -65.6% | 0.19% | -85.9% |
| LOGC | LOGICBIO THERAPEUTICS INC | $422,000 | -49.5% | 182,630 | 0.0% | 0.13% | -52.4% | |
| Sell | NYXOAH SA | $371,000 | -22.2% | 16,110 | -1.2% | 0.11% | -26.3% | |
| RENOVACOR INC*w exp 99/99/999 | $240,000 | -12.4% | 400,000 | 0.0% | 0.07% | -17.2% | ||
| CMAX | CAREMAX INC | $236,000 | -20.5% | 30,741 | 0.0% | 0.07% | -25.3% | |
| NLTX | NEOLEUKIN THERAPEUTICS INC | $185,000 | -33.2% | 38,312 | 0.0% | 0.06% | -36.4% | |
| UHS | Sell | UNIVERSAL HEALTH SERVICES INCcl b | $161,000 | -98.8% | 1,243 | -98.8% | 0.05% | -98.9% |
| MESO | New | MESOBLAST LTDspons adr | $128,000 | – | 26,660 | +100.0% | 0.04% | – |
| HUMACYTE INC*w exp 09/21/202 | $114,000 | -21.4% | 49,998 | 0.0% | 0.03% | -26.1% | ||
| CMAXW | CAREMAX INC*w exp 06/08/2026 | $20,000 | -44.4% | 12,808 | 0.0% | 0.01% | -45.5% | |
| RUBY | Exit | RUBIUS THERAPEUTICS INC | $0 | – | -6,200 | -100.0% | -0.04% | – |
| EVLO | Exit | EVELO BIOSCIENCES INCput | $0 | – | -206,300 | -100.0% | -0.46% | – |
| PTGX | Exit | PROTAGONIST THERAPEUTICS INC | $0 | – | -90,000 | -100.0% | -0.51% | – |
| CRTX | Exit | CORTEXYME INCput | $0 | – | -22,200 | -100.0% | -0.65% | – |
| CBIO | Exit | CATALYST BIOSCIENCES INC | $0 | – | -623,892 | -100.0% | -0.82% | – |
| RDUS | Exit | RADIUS HEALTH INC | $0 | – | -241,905 | -100.0% | -0.96% | – |
| SPRB | Exit | SPRUCE BIOSCIENCES INC | $0 | – | -603,027 | -100.0% | -1.16% | – |
| CCRN | Exit | CROSS COUNTRY HEALTHCARE INC | $0 | – | -199,460 | -100.0% | -1.35% | – |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -228,318 | -100.0% | -1.36% | – |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -65,500 | -100.0% | -1.46% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -25,500 | -100.0% | -1.47% | – |
| HQY | Exit | HEALTHEQUITY INC | $0 | – | -73,458 | -100.0% | -1.52% | – |
| HCA | Exit | HCA HEALTHCARE INC | $0 | – | -56,409 | -100.0% | -4.36% | – |
| SOLY | Exit | SOLITON INC | $0 | – | -824,803 | -100.0% | -5.35% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| VIKING THERAPEUTICS INC | 24 | Q3 2023 | 3.4% |
| UNITED THERAPEUTICS ORD | 23 | Q3 2023 | 8.3% |
| CARDINAL HEALTH ORD | 20 | Q2 2022 | 7.2% |
| SANOFI SA | 19 | Q3 2022 | 9.8% |
| MEDTRONIC PLC | 18 | Q3 2023 | 5.2% |
| CATALYST BIOSCIENCES INC | 18 | Q3 2021 | 17.8% |
| PFENEX ORD | 18 | Q4 2019 | 5.9% |
| AEGLEA BIOTHERAPEUTICS INC | 18 | Q1 2023 | 1.1% |
| HCA HEALTHCARE INC | 17 | Q2 2022 | 5.5% |
| MCKESSON ORD | 17 | Q1 2022 | 6.0% |
View Sio Capital Management, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Modular Medical, Inc. | February 13, 2023 | 1,091,479 | 10.0% |
| Cellectar Biosciences, Inc. | February 10, 2022 | ? | ? |
| CURIS INC | February 10, 2022 | 3,866,645 | 4.2% |
| Salarius Pharmaceuticals, Inc. | February 10, 2022 | 1,354,291 | 3.0% |
| Larimar Therapeutics, Inc. | February 16, 2021 | 188,661 | 1.2% |
| ACHIEVE LIFE SCIENCES, INC. | February 14, 2020 | ? | ? |
| Bionano Genomics, Inc | February 14, 2020 | 1,210,821 | 4.6% |
| Brickell Biotech, Inc. | February 14, 2020 | ? | ? |
| Trillium Therapeutics Inc. | February 14, 2020 | 2,751,186 | 9.8% |
| ZAFGEN, INC. | February 14, 2020 | 2,283,164 | 6.1% |
View Sio Capital Management, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-12 |
| 13F-HR | 2023-02-13 |
| SC 13G | 2023-02-13 |
| 13F-HR | 2022-11-14 |
View Sio Capital Management, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.