$302 Million is the total value of Sio Capital Management, LLC's 66 reported holdings in Q1 2022. The portfolio turnover from Q4 2021 to Q1 2022 was 51.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| VRTX | New | VERTEX PHARMACEUTICALS INCput | $34,709,000 | – | 133,000 | +100.0% | 11.48% | – |
| MSAC | MEDICUS SCIENCES ACQUISITION | $22,719,000 | +0.6% | 2,323,000 | 0.0% | 7.52% | +10.4% | |
| CI | Sell | CIGNA CORP | $16,253,000 | -41.7% | 67,830 | -44.1% | 5.38% | -36.0% |
| MRK | Sell | MERCK & CO INC | $16,013,000 | -10.6% | 195,160 | -16.5% | 5.30% | -1.9% |
| SNY | Buy | SANOFI SAsponsored adr | $15,402,000 | +248.4% | 300,000 | +239.9% | 5.10% | +282.2% |
| VRTX | New | VERTEX PHARMACEUTICALS INCcall | $15,267,000 | – | 58,500 | +100.0% | 5.05% | – |
| LH | New | LABORATORY CORPORATION OF AMERICA HOLDINGS | $13,006,000 | – | 49,328 | +100.0% | 4.30% | – |
| INGN | Buy | INOGEN INC | $12,971,000 | +332.1% | 400,086 | +353.1% | 4.29% | +374.1% |
| ABC | Sell | AMERISOURCEBERGEN CORP | $12,883,000 | -0.5% | 83,271 | -14.5% | 4.26% | +9.2% |
| MCK | Sell | MCKESSON CORP | $10,562,000 | -25.5% | 34,501 | -39.5% | 3.49% | -18.3% |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $9,915,000 | -13.7% | 55,262 | +3.9% | 3.28% | -5.3% |
| GLPG | Sell | GALAPAGOS NVspon adr | $9,098,000 | -36.9% | 146,696 | -43.9% | 3.01% | -30.7% |
| CNC | Sell | CENTENE CORP | $8,146,000 | -21.4% | 96,762 | -23.1% | 2.70% | -13.7% |
| VREX | New | VAREX IMAGING CORP | $6,717,000 | – | 315,486 | +100.0% | 2.22% | – |
| IONS | Sell | IONIS PHARMACEUTICALS INC | $6,503,000 | -33.8% | 175,568 | -45.6% | 2.15% | -27.3% |
| NTUS | Buy | NATUS MEDICAL INC | $5,034,000 | +96.9% | 191,564 | +77.9% | 1.66% | +116.0% |
| VAPO | Buy | VAPOTHERM INC | $4,907,000 | +31.6% | 353,006 | +96.1% | 1.62% | +44.4% |
| MEDP | New | MEDPACE HOLDINGS INC | $4,646,000 | – | 28,400 | +100.0% | 1.54% | – |
| CRIS | Sell | CURIS INC | $4,559,000 | -75.2% | 1,915,460 | -50.5% | 1.51% | -72.8% |
| ALBO | Sell | ALBIREO PHARMA INC | $4,312,000 | -13.4% | 144,546 | -32.4% | 1.43% | -5.1% |
| NKTR | New | NEKTAR THERAPEUTICSput | $3,739,000 | – | 693,700 | +100.0% | 1.24% | – |
| NARI | New | INARI MEDICAL INC | $3,645,000 | – | 40,210 | +100.0% | 1.21% | – |
| MIRM | Sell | MIRUM PHARMACEUTICALS INC | $3,551,000 | -17.6% | 161,285 | -40.3% | 1.18% | -9.6% |
| XENE | New | XENON PHARMACEUTICALS INC | $3,233,000 | – | 105,756 | +100.0% | 1.07% | – |
| RENOVACOR INC | $3,120,000 | -44.9% | 735,908 | 0.0% | 1.03% | -39.6% | ||
| PNT | POINT BIOPHARMA GLOBAL INC | $3,010,000 | +42.3% | 377,684 | 0.0% | 1.00% | +56.1% | |
| VKTX | Buy | VIKING THERAPEUTICS INC | $2,999,000 | -1.3% | 999,829 | +51.3% | 0.99% | +8.3% |
| AFMD | New | AFFIMED NV | $2,813,000 | – | 643,664 | +100.0% | 0.93% | – |
| INBX | New | INHIBRX INC | $2,768,000 | – | 124,250 | +100.0% | 0.92% | – |
| HSAQ | HEALTH SCIENCES ACQUISITIONS CORP 2 | $2,478,000 | -1.7% | 250,000 | 0.0% | 0.82% | +7.9% | |
| EUCRU | EUCRATES BIOMEDICAL ACQUISITION CORP.unit 10/23/2027 | $2,452,000 | -1.2% | 248,674 | 0.0% | 0.81% | +8.4% | |
| MRUS | MERUS NV | $2,380,000 | -16.8% | 90,000 | 0.0% | 0.79% | -8.8% | |
| BCYC | Sell | BICYCLE THERAPEUTICS PLCsponsored ads | $2,316,000 | -29.5% | 52,788 | -2.2% | 0.77% | -22.7% |
| Buy | PARDES BIOSCIENCES INC | $2,278,000 | -55.5% | 315,564 | +1.0% | 0.75% | -51.1% | |
| FUSN | FUSION PHARMACEUTICALS INC | $2,018,000 | +86.3% | 259,763 | 0.0% | 0.67% | +104.9% | |
| AGLE | Buy | AEGLEA BIO THERAPEUTICS INC | $2,004,000 | -15.4% | 871,101 | +74.7% | 0.66% | -7.1% |
| MBRX | MOLECULIN BIOTECH INC | $1,852,000 | -4.3% | 1,040,529 | 0.0% | 0.61% | +5.1% | |
| VNDA | New | VANDA PHARMACEUTICALS INC | $1,838,000 | – | 162,478 | +100.0% | 0.61% | – |
| CNTB | New | CONNECT BIOPHARMA HOLDINGS LTDads | $1,805,000 | – | 597,678 | +100.0% | 0.60% | – |
| CBAY | CYMABAY THERAPEUTICS INC | $1,749,000 | -8.0% | 562,339 | 0.0% | 0.58% | +1.0% | |
| NBSE | NEUBASE THERAPEUTICS INC | $1,704,000 | -33.1% | 906,445 | 0.0% | 0.56% | -26.6% | |
| SRRA | Sell | SIERRA ONCOLOGY INC | $1,563,000 | -24.7% | 48,768 | -48.9% | 0.52% | -17.4% |
| Sell | ISOPLEXIS CORP | $1,396,000 | -69.3% | 407,102 | -17.8% | 0.46% | -66.3% | |
| CYCC | CYCLACEL PHARMACEUTICALS INC | $1,289,000 | -21.6% | 422,598 | 0.0% | 0.43% | -14.1% | |
| New | TYRA BIOSCIENCES INC | $1,188,000 | – | 111,033 | +100.0% | 0.39% | – | |
| ASLN | ASLAN PHARMACEUTICALS LTDads | $1,143,000 | -19.7% | 1,270,758 | 0.0% | 0.38% | -11.9% | |
| ANIP | ANI PHARMACEUTICALS INC | $1,124,000 | -39.0% | 40,000 | 0.0% | 0.37% | -33.1% | |
| SYRS | Buy | SYROS PHARMACEUTICALS INC | $1,074,000 | -63.4% | 902,907 | +0.2% | 0.36% | -59.9% |
| SVRA | Buy | SAVARA INC | $938,000 | +16.2% | 716,262 | +10.0% | 0.31% | +27.6% |
| ELEV | Buy | ELEVATION ONCOLOGY INC | $907,000 | -39.7% | 359,731 | +43.9% | 0.30% | -33.9% |
| NXTC | NEXTCURE INC | $632,000 | -19.0% | 130,000 | 0.0% | 0.21% | -11.1% | |
| XFOR | X4 PHARMACEUTICALS INC | $485,000 | -23.5% | 276,909 | 0.0% | 0.16% | -16.2% | |
| AVAH | Sell | AVEANNA HEALTHCARE HOLDINGS INC | $449,000 | -93.7% | 131,812 | -86.2% | 0.15% | -93.0% |
| VINC | VINCERX PHARMA INC | $408,000 | -60.8% | 102,049 | 0.0% | 0.14% | -57.0% | |
| RDUS | New | RADIUS HEALTH INC | $392,000 | – | 44,400 | +100.0% | 0.13% | – |
| NYXOAH SA | $308,000 | -17.0% | 16,110 | 0.0% | 0.10% | -8.9% | ||
| BHC | New | BAUSCH HEALTH COMPANIES INCput | $276,000 | – | 12,100 | +100.0% | 0.09% | – |
| AYLA | Sell | AYALA PHARMACEUTICALS INC | $240,000 | -64.7% | 60,220 | -24.7% | 0.08% | -61.5% |
| KOD | New | KODIAK SCIENCES INCcall | $236,000 | – | 30,600 | +100.0% | 0.08% | – |
| CMAX | CAREMAX INC | $230,000 | -2.5% | 30,741 | 0.0% | 0.08% | +7.0% | |
| RENOVACOR INC*w exp 99/99/999 | $168,000 | -30.0% | 400,000 | 0.0% | 0.06% | -22.2% | ||
| KZR | Sell | KEZAR LIFE SCIENCES INC | $152,000 | -95.7% | 9,168 | -95.7% | 0.05% | -95.3% |
| LOGC | LOGICBIO THERAPEUTICS INC | $124,000 | -70.6% | 182,630 | 0.0% | 0.04% | -67.7% | |
| HUMACYTE INC*w exp 09/21/202 | $97,000 | -14.9% | 49,998 | 0.0% | 0.03% | -5.9% | ||
| NLTX | NEOLEUKIN THERAPEUTICS INC | $72,000 | -61.1% | 38,312 | 0.0% | 0.02% | -57.1% | |
| CMAXW | CAREMAX INC*w exp 06/08/2026 | $20,000 | 0.0% | 12,808 | 0.0% | 0.01% | +16.7% | |
| MESO | Exit | MESOBLAST LTDspons adr | $0 | – | -26,660 | -100.0% | -0.04% | – |
| UHS | Exit | UNIVERSAL HEALTH SERVICES INCcl b | $0 | – | -1,243 | -100.0% | -0.05% | – |
| SLRX | Exit | SALARIUS PHARMACEUTICALS INC | $0 | – | -1,354,291 | -100.0% | -0.20% | – |
| CRIS | Exit | CURIS INCcall | $0 | – | -144,000 | -100.0% | -0.21% | – |
| ARDX | Exit | ARDELYX INC | $0 | – | -994,604 | -100.0% | -0.33% | – |
| MEIP | Exit | MEI PHARMA INC | $0 | – | -426,047 | -100.0% | -0.34% | – |
| NEOG | Exit | NEOGEN CORPput | $0 | – | -25,100 | -100.0% | -0.34% | – |
| LPTX | Exit | LEAP THERAPEUTICS INC | $0 | – | -440,000 | -100.0% | -0.43% | – |
| BLU | Exit | BELLUS HEALTH INC NEWput | $0 | – | -181,800 | -100.0% | -0.44% | – |
| DTIL | Exit | PRECISION BIOSCIENCES INC | $0 | – | -257,167 | -100.0% | -0.57% | – |
| RIGL | Exit | RIGEL PHARMACEUTICALS INC | $0 | – | -913,621 | -100.0% | -0.73% | – |
| AMED | Exit | AMEDISYS INC | $0 | – | -15,000 | -100.0% | -0.73% | – |
| HZNP | Exit | HORIZON THERAPEUTICS PLC | $0 | – | -29,319 | -100.0% | -0.95% | – |
| OYST | Exit | OYSTER POINT PHARMA INC | $0 | – | -181,857 | -100.0% | -1.00% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INC | $0 | – | -42,379 | -100.0% | -1.19% | – |
| OGN | Exit | ORGANON & CO | $0 | – | -177,659 | -100.0% | -1.63% | – |
| ITGR | Exit | INTEGER HOLDINGS CORP | $0 | – | -77,881 | -100.0% | -2.01% | – |
| HLF | Exit | HERBALIFE NUTRITION LTD | $0 | – | -241,437 | -100.0% | -2.98% | – |
| GLD | Exit | SPDR GOLD TR | $0 | – | -89,890 | -100.0% | -4.63% | – |
| CAH | Exit | CARDINAL HEALTH INC | $0 | – | -335,271 | -100.0% | -5.20% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-05-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| VIKING THERAPEUTICS INC | 24 | Q3 2023 | 3.4% |
| UNITED THERAPEUTICS ORD | 23 | Q3 2023 | 8.3% |
| CARDINAL HEALTH ORD | 20 | Q2 2022 | 7.2% |
| SANOFI SA | 19 | Q3 2022 | 9.8% |
| MEDTRONIC PLC | 18 | Q3 2023 | 5.2% |
| CATALYST BIOSCIENCES INC | 18 | Q3 2021 | 17.8% |
| PFENEX ORD | 18 | Q4 2019 | 5.9% |
| AEGLEA BIOTHERAPEUTICS INC | 18 | Q1 2023 | 1.1% |
| HCA HEALTHCARE INC | 17 | Q2 2022 | 5.5% |
| MCKESSON ORD | 17 | Q1 2022 | 6.0% |
View Sio Capital Management, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Modular Medical, Inc. | February 13, 2023 | 1,091,479 | 10.0% |
| Cellectar Biosciences, Inc. | February 10, 2022 | ? | ? |
| CURIS INC | February 10, 2022 | 3,866,645 | 4.2% |
| Salarius Pharmaceuticals, Inc. | February 10, 2022 | 1,354,291 | 3.0% |
| Larimar Therapeutics, Inc. | February 16, 2021 | 188,661 | 1.2% |
| ACHIEVE LIFE SCIENCES, INC. | February 14, 2020 | ? | ? |
| Bionano Genomics, Inc | February 14, 2020 | 1,210,821 | 4.6% |
| Brickell Biotech, Inc. | February 14, 2020 | ? | ? |
| Trillium Therapeutics Inc. | February 14, 2020 | 2,751,186 | 9.8% |
| ZAFGEN, INC. | February 14, 2020 | 2,283,164 | 6.1% |
View Sio Capital Management, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-12 |
| 13F-HR | 2023-02-13 |
| SC 13G | 2023-02-13 |
| 13F-HR | 2022-11-14 |
View Sio Capital Management, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.