$314 Million is the total value of Sio Capital Management, LLC's 61 reported holdings in Q3 2021. The portfolio turnover from Q2 2021 to Q3 2021 was 52.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CI | Buy | CIGNA CORP | $27,667,000 | +33.8% | 138,224 | +58.5% | 8.82% | +71.6% |
| CRIS | Sell | CURIS INC | $22,818,000 | -16.0% | 2,914,127 | -13.4% | 7.27% | +7.8% |
| GLD | Buy | SPDR GOLD SHARES | $16,841,000 | +6.5% | 102,553 | +7.5% | 5.37% | +36.7% |
| SOLY | SOLITON INC | $16,793,000 | -9.5% | 824,803 | 0.0% | 5.35% | +16.1% | |
| UHS | Buy | UNIVERSAL HEALTH SERVICES INCcl b | $13,982,000 | +30.6% | 101,051 | +38.2% | 4.46% | +67.4% |
| HCA | Sell | HCA HEALTHCARE INC | $13,692,000 | +1.0% | 56,409 | -14.0% | 4.36% | +29.5% |
| GLPG | New | GALAPAGOS NVspon adr | $11,822,000 | – | 224,719 | +100.0% | 3.77% | – |
| AVAH | Buy | AVEANNA HEALTHCARE HOLDINGS INC | $11,206,000 | -24.6% | 1,397,272 | +16.3% | 3.57% | -3.3% |
| CNC | Buy | CENTENE CORP | $11,168,000 | -1.6% | 179,232 | +15.2% | 3.56% | +26.2% |
| UTHR | Buy | UNITED THERAPEUTICS CORP | $10,917,000 | +30.3% | 59,146 | +26.6% | 3.48% | +67.1% |
| MRK | New | MERCK & CO INC | $9,389,000 | – | 125,000 | +100.0% | 2.99% | – |
| HLF | Buy | HERBALIFE NUTRITION LTD | $9,155,000 | +12.1% | 216,012 | +39.5% | 2.92% | +43.8% |
| MCK | Sell | MCKESSON CORP | $8,732,000 | -8.0% | 43,797 | -11.7% | 2.78% | +18.0% |
| CAH | Buy | CARDINAL HEALTH INC | $6,995,000 | +262.2% | 141,423 | +318.2% | 2.23% | +364.6% |
| New | RENOVACOR INC | $6,664,000 | – | 736,323 | +100.0% | 2.12% | – | |
| ALBO | Sell | ALBIREO PHARMA INC | $6,661,000 | -28.7% | 213,493 | -19.6% | 2.12% | -8.6% |
| MIRM | Sell | MIRUM PHARMACEUTICALS INC | $4,960,000 | -36.9% | 248,978 | -45.3% | 1.58% | -19.1% |
| ITGR | Sell | INTEGER HOLDINGS CORP | $4,904,000 | -22.1% | 54,891 | -17.9% | 1.56% | -0.1% |
| HQY | Buy | HEALTHEQUITY INC | $4,757,000 | -9.0% | 73,458 | +13.1% | 1.52% | +16.6% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $4,625,000 | -4.0% | 25,500 | +6.7% | 1.47% | +23.0% |
| GILD | New | GILEAD SCIENCES INC | $4,575,000 | – | 65,500 | +100.0% | 1.46% | – |
| KURA | Buy | KURA ONCOLOGY INC | $4,276,000 | -7.7% | 228,318 | +2.7% | 1.36% | +18.3% |
| XFOR | X4 PHARMACEUTICALS INC | $4,256,000 | -18.6% | 804,597 | 0.0% | 1.36% | +4.4% | |
| CCRN | Sell | CROSS COUNTRY HEALTHCARE INC | $4,237,000 | -8.3% | 199,460 | -28.7% | 1.35% | +17.7% |
| VKTX | Buy | VIKING THERAPEUTICS INC | $4,150,000 | +11.8% | 660,813 | +6.6% | 1.32% | +43.3% |
| SYRS | Buy | SYROS PHARMACEUTICALS INC | $4,026,000 | -7.7% | 900,677 | +12.6% | 1.28% | +18.4% |
| SPRB | Sell | SPRUCE BIOSCIENCES INC | $3,624,000 | -50.1% | 603,027 | -6.8% | 1.16% | -36.0% |
| AYLA | Sell | AYALA PHARMACEUTICALS INC | $3,613,000 | -34.7% | 318,599 | -41.3% | 1.15% | -16.2% |
| AGLE | Buy | AEGLEA BIO THERAPEUTICS INC | $3,546,000 | +26.6% | 446,000 | +10.8% | 1.13% | +62.1% |
| RIGL | Buy | RIGEL PHARMACEUTICALS INC | $3,316,000 | -7.9% | 913,621 | +10.1% | 1.06% | +18.1% |
| NBSE | Buy | NEUBASE THERAPEUTICS INC | $3,272,000 | -21.4% | 906,445 | +4.3% | 1.04% | +0.9% |
| HZNP | Sell | HORIZON THERAPEUTICS PLC | $3,212,000 | -49.2% | 29,319 | -56.5% | 1.02% | -34.8% |
| MBRX | Buy | MOLECULIN BIOTECH INC | $3,122,000 | -15.3% | 1,040,529 | +3.6% | 1.00% | +8.5% |
| RDUS | Buy | RADIUS HEALTH INC | $3,002,000 | -31.7% | 241,905 | +0.4% | 0.96% | -12.4% |
| DTIL | Sell | PRECISION BIOSCIENCES INC | $2,968,000 | -19.2% | 257,167 | -12.4% | 0.95% | +3.6% |
| CBIO | CATALYST BIOSCIENCES INC | $2,564,000 | -5.1% | 623,892 | 0.0% | 0.82% | +21.8% | |
| EUCRU | Sell | EUCRATES BIOMEDICAL ACQUISITION CORP.unit 10/23/2027 | $2,474,000 | -19.2% | 248,674 | -17.1% | 0.79% | +3.7% |
| HSAQ | HEALTH SCIENCES ACQUISITIONS CORP 2 | $2,473,000 | -3.0% | 250,000 | 0.0% | 0.79% | +24.3% | |
| ASLN | Sell | ASLAN PHARMACEUTICALS LTDads | $2,262,000 | -53.9% | 1,270,758 | -14.6% | 0.72% | -41.0% |
| CYCC | Buy | CYCLACEL PHARMACEUTICALS INC | $2,227,000 | -9.8% | 422,598 | +1.4% | 0.71% | +15.6% |
| SRRA | Buy | SIERRA ONCOLOGY INC | $2,092,000 | +15.2% | 95,450 | +2.4% | 0.67% | +47.9% |
| FUSN | Sell | FUSION PHARMACEUTICALS INC | $2,057,000 | -4.3% | 259,763 | -2.4% | 0.66% | +22.8% |
| CBAY | CYMABAY THERAPEUTICS INC | $2,053,000 | -16.3% | 562,339 | 0.0% | 0.65% | +7.2% | |
| CRTX | New | CORTEXYME INCput | $2,035,000 | – | 22,200 | +100.0% | 0.65% | – |
| LPTX | New | LEAP THERAPEUTICS INC | $1,764,000 | – | 440,000 | +100.0% | 0.56% | – |
| VINC | Sell | VINCERX PHARMA INC | $1,650,000 | -9.8% | 102,049 | -27.6% | 0.53% | +15.6% |
| PTGX | New | PROTAGONIST THERAPEUTICS INC | $1,595,000 | – | 90,000 | +100.0% | 0.51% | – |
| EVLO | New | EVELO BIOSCIENCES INCput | $1,452,000 | – | 206,300 | +100.0% | 0.46% | – |
| SLRX | SALARIUS PHARMACEUTICALS INC | $1,381,000 | -3.8% | 1,354,291 | 0.0% | 0.44% | +23.2% | |
| ARNA | ARENA PHARMACEUTICALS INC | $1,294,000 | -12.7% | 21,738 | 0.0% | 0.41% | +11.9% | |
| MEIP | MEI PHARMA INC | $1,176,000 | -3.1% | 426,047 | 0.0% | 0.38% | +24.2% | |
| NTUS | New | NATUS MEDICAL INC | $987,000 | – | 39,354 | +100.0% | 0.32% | – |
| LOGC | LOGICBIO THERAPEUTICS INC | $836,000 | +3.1% | 182,630 | 0.0% | 0.27% | +32.2% | |
| ARDX | Buy | ARDELYX INC | $755,000 | -81.1% | 572,082 | +8.8% | 0.24% | -75.7% |
| New | NYXOAH SA | $477,000 | – | 16,310 | +100.0% | 0.15% | – | |
| CMAX | Sell | CAREMAX INC | $297,000 | -35.3% | 30,741 | -29.4% | 0.10% | -16.7% |
| NLTX | NEOLEUKIN THERAPEUTICS INC | $277,000 | -21.8% | 38,312 | 0.0% | 0.09% | 0.0% | |
| New | RENOVACOR INC*w exp 99/99/999 | $274,000 | – | 400,000 | +100.0% | 0.09% | – | |
| New | HUMACYTE INC*w exp 09/21/202 | $145,000 | – | 49,998 | +100.0% | 0.05% | – | |
| RUBY | RUBIUS THERAPEUTICS INC | $111,000 | -26.5% | 6,200 | 0.0% | 0.04% | -7.9% | |
| CMAXW | New | CAREMAX INCw exp 06/08/2026 | $36,000 | – | 12,808 | +100.0% | 0.01% | – |
| MESO | Exit | MESOBLAST LTDput | $0 | – | -54,800 | -100.0% | -0.10% | – |
| CVRX | Exit | CVRX INC | $0 | – | -15,000 | -100.0% | -0.10% | – |
| SEER | Exit | SEER INC | $0 | – | -23,775 | -100.0% | -0.19% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -77,477 | -100.0% | -0.20% | – |
| BCEL | Exit | ATRECA INC | $0 | – | -113,455 | -100.0% | -0.24% | – |
| IDYA | Exit | IDEAYA BIOSCIENCES INC | $0 | – | -48,298 | -100.0% | -0.25% | – |
| AHACU | Exit | ALPHA HEALTHCARE ACQUISITION CORPunit 10/01/2023 | $0 | – | -100,000 | -100.0% | -0.28% | – |
| CHAQ | Exit | CHARDAN HEALTHCARE ACQUISITION 2 CORP | $0 | – | -200,000 | -100.0% | -0.50% | – |
| GOSS | Exit | GOSSAMER BIO INC | $0 | – | -261,400 | -100.0% | -0.53% | – |
| MRSN | Exit | MERSANA THERAPEUTICS INC | $0 | – | -157,259 | -100.0% | -0.53% | – |
| TVTX | Exit | TRAVERE THERAPEUTICS INC | $0 | – | -150,000 | -100.0% | -0.54% | – |
| AMN | Exit | AMN HEALTHCARE SERVICES INC | $0 | – | -26,001 | -100.0% | -0.63% | – |
| PRQR | Exit | PROQR THERAPEUTICS NV | $0 | – | -380,045 | -100.0% | -0.64% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -112,587 | -100.0% | -0.75% | – |
| ASGN | Exit | ASGN INC | $0 | – | -36,692 | -100.0% | -0.88% | – |
| AUTL | Exit | AUTOLUS THERAPEUTICS PLCspon ads | $0 | – | -591,870 | -100.0% | -0.98% | – |
| EPIX | Exit | ESSA PHARMA INC | $0 | – | -148,127 | -100.0% | -1.05% | – |
| NARI | Exit | INARI MEDICAL INC | $0 | – | -46,332 | -100.0% | -1.07% | – |
| CHAQU | Exit | CHARDAN HEALTHCARE ACQUISITION 2 CORPunit | $0 | – | -400,000 | -100.0% | -1.09% | – |
| SYNH | Exit | SYNEOS HEALTH INCcl a | $0 | – | -62,598 | -100.0% | -1.39% | – |
| CHRS | Exit | COHERUS BIOSCIENCES INC | $0 | – | -413,733 | -100.0% | -1.42% | – |
| AFMD | Exit | AFFIMED NV | $0 | – | -714,576 | -100.0% | -1.51% | – |
| AMGN | Exit | AMGEN INC | $0 | – | -35,000 | -100.0% | -2.12% | – |
| HRC | Exit | HILL-ROM HOLDINGS INC | $0 | – | -76,647 | -100.0% | -2.16% | – |
| ASND | Exit | ASCENDIS PHARMA A/Sput | $0 | – | -251,900 | -100.0% | -8.24% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-11-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| VIKING THERAPEUTICS INC | 24 | Q3 2023 | 3.4% |
| UNITED THERAPEUTICS ORD | 23 | Q3 2023 | 8.3% |
| CARDINAL HEALTH ORD | 20 | Q2 2022 | 7.2% |
| SANOFI SA | 19 | Q3 2022 | 9.8% |
| MEDTRONIC PLC | 18 | Q3 2023 | 5.2% |
| CATALYST BIOSCIENCES INC | 18 | Q3 2021 | 17.8% |
| PFENEX ORD | 18 | Q4 2019 | 5.9% |
| AEGLEA BIOTHERAPEUTICS INC | 18 | Q1 2023 | 1.1% |
| HCA HEALTHCARE INC | 17 | Q2 2022 | 5.5% |
| MCKESSON ORD | 17 | Q1 2022 | 6.0% |
View Sio Capital Management, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Modular Medical, Inc. | February 13, 2023 | 1,091,479 | 10.0% |
| Cellectar Biosciences, Inc. | February 10, 2022 | ? | ? |
| CURIS INC | February 10, 2022 | 3,866,645 | 4.2% |
| Salarius Pharmaceuticals, Inc. | February 10, 2022 | 1,354,291 | 3.0% |
| Larimar Therapeutics, Inc. | February 16, 2021 | 188,661 | 1.2% |
| ACHIEVE LIFE SCIENCES, INC. | February 14, 2020 | ? | ? |
| Bionano Genomics, Inc | February 14, 2020 | 1,210,821 | 4.6% |
| Brickell Biotech, Inc. | February 14, 2020 | ? | ? |
| Trillium Therapeutics Inc. | February 14, 2020 | 2,751,186 | 9.8% |
| ZAFGEN, INC. | February 14, 2020 | 2,283,164 | 6.1% |
View Sio Capital Management, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-12 |
| 13F-HR | 2023-02-13 |
| SC 13G | 2023-02-13 |
| 13F-HR | 2022-11-14 |
View Sio Capital Management, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.