$402 Million is the total value of Sio Capital Management, LLC's 74 reported holdings in Q2 2021. The portfolio turnover from Q1 2021 to Q2 2021 was 53.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ASND | New | ASCENDIS PHARMA A/Sput | $33,137,000 | – | 251,900 | +100.0% | 8.24% | – |
| CRIS | Sell | CURIS INC | $27,151,000 | -45.3% | 3,364,405 | -23.2% | 6.75% | -33.0% |
| CI | Sell | CIGNA CORP | $20,671,000 | -20.1% | 87,192 | -18.5% | 5.14% | -2.1% |
| SOLY | SOLITON INC | $18,550,000 | +28.0% | 824,803 | 0.0% | 4.61% | +56.7% | |
| GLD | Sell | SPDR GOLD SHARES | $15,806,000 | +1.9% | 95,430 | -1.6% | 3.93% | +24.7% |
| AVAH | New | AVEANNA HEALTHCARE HOLDINGS INC | $14,864,000 | – | 1,201,607 | +100.0% | 3.70% | – |
| HCA | Sell | HCA HEALTHCARE INC | $13,557,000 | -1.6% | 65,573 | -10.4% | 3.37% | +20.5% |
| CNC | Sell | CENTENE CORP | $11,349,000 | -18.4% | 155,616 | -28.5% | 2.82% | 0.0% |
| UHS | Buy | UNIVERSAL HEALTH SERVICES INCcl b | $10,709,000 | +17.8% | 73,135 | +7.3% | 2.66% | +44.3% |
| MCK | Buy | MCKESSON CORP | $9,490,000 | +25.1% | 49,624 | +27.6% | 2.36% | +53.2% |
| ALBO | Sell | ALBIREO PHARMA INC | $9,344,000 | -1.2% | 265,616 | -1.0% | 2.32% | +21.0% |
| HRC | Sell | HILL-ROM HOLDINGS INC | $8,706,000 | -26.8% | 76,647 | -28.8% | 2.16% | -10.4% |
| AMGN | New | AMGEN INC | $8,531,000 | – | 35,000 | +100.0% | 2.12% | – |
| UTHR | Sell | UNITED THERAPEUTICS CORP | $8,381,000 | -10.6% | 46,712 | -16.7% | 2.08% | +9.5% |
| HLF | Buy | HERBALIFE NUTRITION LTD | $8,165,000 | +23.8% | 154,838 | +4.1% | 2.03% | +51.6% |
| MIRM | Buy | MIRUM PHARMACEUTICALS INC | $7,865,000 | -9.2% | 454,892 | +4.1% | 1.96% | +11.1% |
| SPRB | Sell | SPRUCE BIOSCIENCES INC | $7,256,000 | -46.2% | 647,239 | -20.4% | 1.80% | -34.1% |
| HZNP | Buy | HORIZON THERAPEUTICS PLC | $6,318,000 | +5.9% | 67,471 | +4.1% | 1.57% | +29.7% |
| ITGR | New | INTEGER HOLDINGS CORP | $6,295,000 | – | 66,828 | +100.0% | 1.56% | – |
| AFMD | Buy | AFFIMED NV | $6,074,000 | +40.1% | 714,576 | +30.4% | 1.51% | +71.6% |
| CHRS | Sell | COHERUS BIOSCIENCES INC | $5,722,000 | -53.8% | 413,733 | -51.2% | 1.42% | -43.4% |
| SYNH | Buy | SYNEOS HEALTH INCcl a | $5,602,000 | +23.0% | 62,598 | +4.3% | 1.39% | +50.8% |
| AYLA | Buy | AYALA PHARMACEUTICALS INC | $5,533,000 | +3.5% | 542,977 | +10.8% | 1.38% | +26.7% |
| HQY | New | HEALTHEQUITY INC | $5,228,000 | – | 64,958 | +100.0% | 1.30% | – |
| XFOR | X4 PHARMACEUTICALS INC | $5,230,000 | -24.5% | 804,597 | 0.0% | 1.30% | -7.5% | |
| ASLN | Buy | ASLAN PHARMACEUTICALS LTDads | $4,912,000 | +1.2% | 1,488,508 | +2.8% | 1.22% | +24.0% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $4,819,000 | +6.5% | 23,900 | +13.4% | 1.20% | +30.4% |
| KURA | Buy | KURA ONCOLOGY INC | $4,634,000 | -23.2% | 222,263 | +4.1% | 1.15% | -6.0% |
| CCRN | Sell | CROSS COUNTRY HEALTHCARE INC | $4,620,000 | -14.6% | 279,850 | -35.4% | 1.15% | +4.6% |
| RDUS | Buy | RADIUS HEALTH INC | $4,395,000 | -8.8% | 240,957 | +4.3% | 1.09% | +11.8% |
| CHAQU | New | CHARDAN HEALTHCARE ACQUISITION 2 CORPunit | $4,368,000 | – | 400,000 | +100.0% | 1.09% | – |
| SYRS | New | SYROS PHARMACEUTICALS INC | $4,360,000 | – | 800,000 | +100.0% | 1.08% | – |
| NARI | New | INARI MEDICAL INC | $4,322,000 | – | 46,332 | +100.0% | 1.07% | – |
| EPIX | Sell | ESSA PHARMA INC | $4,232,000 | -53.4% | 148,127 | -52.6% | 1.05% | -43.0% |
| NBSE | Buy | NEUBASE THERAPEUTICS INC | $4,161,000 | +43.0% | 868,699 | +120.7% | 1.03% | +75.3% |
| ARDX | Sell | ARDELYX INC | $3,987,000 | -16.4% | 525,996 | -27.0% | 0.99% | +2.4% |
| AUTL | New | AUTOLUS THERAPEUTICS PLCspon ads | $3,930,000 | – | 591,870 | +100.0% | 0.98% | – |
| VKTX | Buy | VIKING THERAPEUTICS INC | $3,712,000 | +3.0% | 619,780 | +8.8% | 0.92% | +26.1% |
| MBRX | Buy | MOLECULIN BIOTECH INC | $3,688,000 | -6.1% | 1,004,845 | +4.3% | 0.92% | +14.9% |
| DTIL | Sell | PRECISION BIOSCIENCES INC | $3,674,000 | +7.8% | 293,440 | -10.9% | 0.91% | +31.9% |
| RIGL | New | RIGEL PHARMACEUTICALS INC | $3,601,000 | – | 829,721 | +100.0% | 0.90% | – |
| ASGN | Buy | ASGN INC | $3,557,000 | +7.8% | 36,692 | +6.1% | 0.88% | +31.9% |
| EUCRU | EUCRATES BIOMEDICAL ACQUISITION CORP.unit 10/23/2027 | $3,060,000 | +1.9% | 300,000 | 0.0% | 0.76% | +24.8% | |
| MGNX | Sell | MACROGENICS INC | $3,024,000 | -27.0% | 112,587 | -13.4% | 0.75% | -10.6% |
| AGLE | AEGLEA BIO THERAPEUTICS INC | $2,802,000 | -12.1% | 402,653 | 0.0% | 0.70% | +7.7% | |
| CBIO | CATALYST BIOSCIENCES INC | $2,701,000 | -14.1% | 623,892 | 0.0% | 0.67% | +5.2% | |
| PRQR | Sell | PROQR THERAPEUTICS NV | $2,562,000 | -1.3% | 380,045 | -3.3% | 0.64% | +20.9% |
| HSAQ | HEALTH SCIENCES ACQUISITIONS CORP 2 | $2,550,000 | -8.9% | 250,000 | 0.0% | 0.63% | +11.6% | |
| AMN | Sell | AMN HEALTHCARE SERVICES INC | $2,522,000 | -72.4% | 26,001 | -79.0% | 0.63% | -66.2% |
| CYCC | New | CYCLACEL PHARMACEUTICALS INC | $2,468,000 | – | 416,873 | +100.0% | 0.61% | – |
| CBAY | CYMABAY THERAPEUTICS INC | $2,452,000 | -4.0% | 562,339 | 0.0% | 0.61% | +17.8% | |
| TVTX | New | TRAVERE THERAPEUTICS INC | $2,189,000 | – | 150,000 | +100.0% | 0.54% | – |
| FUSN | Buy | FUSION PHARMACEUTICALS INC | $2,150,000 | -19.6% | 266,107 | +6.7% | 0.53% | -1.7% |
| MRSN | MERSANA THERAPEUTICS INC | $2,136,000 | -16.0% | 157,259 | 0.0% | 0.53% | +2.9% | |
| GOSS | GOSSAMER BIO INC | $2,123,000 | -12.2% | 261,400 | 0.0% | 0.53% | +7.5% | |
| CHAQ | Sell | CHARDAN HEALTHCARE ACQUISITION 2 CORP | $1,992,000 | -68.9% | 200,000 | -66.7% | 0.50% | -62.0% |
| CAH | Sell | CARDINAL HEALTH INC | $1,931,000 | -88.4% | 33,818 | -87.7% | 0.48% | -85.8% |
| VINC | Buy | VINCERX PHARMA INC | $1,830,000 | -9.7% | 140,913 | +34.2% | 0.46% | +10.7% |
| SRRA | Buy | SIERRA ONCOLOGY INC | $1,816,000 | +30.2% | 93,252 | +15.2% | 0.45% | +59.4% |
| ARNA | ARENA PHARMACEUTICALS INC | $1,483,000 | -1.7% | 21,738 | 0.0% | 0.37% | +20.6% | |
| SLRX | Sell | SALARIUS PHARMACEUTICALS INC | $1,436,000 | -68.9% | 1,354,291 | -56.6% | 0.36% | -61.9% |
| MEIP | MEI PHARMA INC | $1,214,000 | -16.9% | 426,047 | 0.0% | 0.30% | +1.7% | |
| AHACU | ALPHA HEALTHCARE ACQUISITION CORPunit 10/01/2023 | $1,141,000 | -8.7% | 100,000 | 0.0% | 0.28% | +11.8% | |
| IDYA | IDEAYA BIOSCIENCES INC | $1,014,000 | -10.7% | 48,298 | 0.0% | 0.25% | +9.6% | |
| BCEL | ATRECA INC | $967,000 | -44.4% | 113,455 | 0.0% | 0.24% | -32.0% | |
| LOGC | New | LOGICBIO THERAPEUTICS INC | $811,000 | – | 182,630 | +100.0% | 0.20% | – |
| FULC | Sell | FULCRUM THERAPEUTICS INC | $812,000 | -64.0% | 77,477 | -59.5% | 0.20% | -55.8% |
| SEER | New | SEER INC | $779,000 | – | 23,775 | +100.0% | 0.19% | – |
| CMAX | New | CAREMAX INCw exp 06/08/2026 | $459,000 | – | 43,549 | +100.0% | 0.11% | – |
| CVRX | New | CVRX INC | $420,000 | – | 15,000 | +100.0% | 0.10% | – |
| MESO | Sell | MESOBLAST LTDput | $410,000 | -12.4% | 54,800 | -3.2% | 0.10% | +7.4% |
| NLTX | NEOLEUKIN THERAPEUTICS INC | $354,000 | -25.0% | 38,312 | 0.0% | 0.09% | -8.3% | |
| RUBY | Sell | RUBIUS THERAPEUTICS INC | $151,000 | -90.5% | 6,200 | -89.6% | 0.04% | -88.2% |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -15,500 | -100.0% | -0.03% | – | |
| BNGO | Exit | BIONANO GENOMICS INC | $0 | – | -24,245 | -100.0% | -0.04% | – |
| Exit | APTOSE BIOSCIENCES INC | $0 | – | -41,100 | -100.0% | -0.05% | – | |
| RAPT | Exit | RAPT THERAPEUTICS INC | $0 | – | -14,298 | -100.0% | -0.06% | – |
| CASI | Exit | CASI PHARMACEUTICALS INC | $0 | – | -203,432 | -100.0% | -0.10% | – |
| DFHTU | Exit | DEERFIELD HEALTHCARE TECHNOLOGY ACQUISITIONS CORPunit 07/16/2025 | $0 | – | -50,000 | -100.0% | -0.13% | – |
| IMAB | Exit | I-MABsponsored ads | $0 | – | -15,000 | -100.0% | -0.15% | – |
| GLYC | Exit | GLYCOMIMETICS INC | $0 | – | -355,517 | -100.0% | -0.22% | – |
| ETON | Exit | ETON PHARMACEUTICALS INC | $0 | – | -162,659 | -100.0% | -0.24% | – |
| SIOX | Exit | SIO GENE THERAPIES INC | $0 | – | -460,248 | -100.0% | -0.24% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -44,430 | -100.0% | -0.29% | – |
| HROW | Exit | HARROW HEALTH INC | $0 | – | -209,623 | -100.0% | -0.29% | – |
| FREQ | Exit | FREQUENCY THERAPEUTICS INCput | $0 | – | -163,100 | -100.0% | -0.31% | – |
| ANIK | Exit | ANIKA THERAPEUTICS INC | $0 | – | -40,000 | -100.0% | -0.33% | – |
| CERC | Exit | CERECOR INC | $0 | – | -552,241 | -100.0% | -0.34% | – |
| OSMT | Exit | OSMOTICA PHARMACEUTICALS PLC | $0 | – | -519,039 | -100.0% | -0.34% | – |
| LLY | Exit | ELI LILLY AND COcall | $0 | – | -9,600 | -100.0% | -0.36% | – |
| ONCT | Exit | ONCTERNAL THERAPEUTICS INC | $0 | – | -323,333 | -100.0% | -0.55% | – |
| LRMR | Exit | LARIMAR THERAPEUTICS INC | $0 | – | -187,223 | -100.0% | -0.56% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -146,142 | -100.0% | -0.66% | – |
| CLRB | Exit | CELLECTAR BIOSCIENCES INC | $0 | – | -2,188,058 | -100.0% | -0.72% | – |
| CNST | Exit | CONSTELLATION PHARMACEUTICALS INC | $0 | – | -166,186 | -100.0% | -0.79% | – |
| NTUS | Exit | NATUS MEDICAL INC | $0 | – | -169,454 | -100.0% | -0.88% | – |
| EBS | Exit | EMERGENT BIOSOLUTIONS INC | $0 | – | -50,000 | -100.0% | -0.94% | – |
| NVAX | Exit | NOVAVAX INC | $0 | – | -25,700 | -100.0% | -0.95% | – |
| VAPO | Exit | VAPOTHERM INC | $0 | – | -258,261 | -100.0% | -1.26% | – |
| TEVA | Exit | TEVA PHARMACEUTICAL INDUSTRIES LTDsponsored ads | $0 | – | -539,947 | -100.0% | -1.26% | – |
| BLRX | Exit | BIOLINE RX LTDsponsored ads | $0 | – | -2,741,776 | -100.0% | -1.55% | – |
| GSK | Exit | GLAXOSMITHKLINE PLCsponsored ads | $0 | – | -257,500 | -100.0% | -1.86% | – |
| ICLR | Exit | ICON PLC | $0 | – | -47,500 | -100.0% | -1.89% | – |
| MRK | Exit | MERCK & CO INC | $0 | – | -125,000 | -100.0% | -1.96% | – |
| CVM | Exit | CEL-SCI CORPput | $0 | – | -695,700 | -100.0% | -2.15% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-08-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| VIKING THERAPEUTICS INC | 24 | Q3 2023 | 3.4% |
| UNITED THERAPEUTICS ORD | 23 | Q3 2023 | 8.3% |
| CARDINAL HEALTH ORD | 20 | Q2 2022 | 7.2% |
| SANOFI SA | 19 | Q3 2022 | 9.8% |
| MEDTRONIC PLC | 18 | Q3 2023 | 5.2% |
| CATALYST BIOSCIENCES INC | 18 | Q3 2021 | 17.8% |
| PFENEX ORD | 18 | Q4 2019 | 5.9% |
| AEGLEA BIOTHERAPEUTICS INC | 18 | Q1 2023 | 1.1% |
| HCA HEALTHCARE INC | 17 | Q2 2022 | 5.5% |
| MCKESSON ORD | 17 | Q1 2022 | 6.0% |
View Sio Capital Management, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Modular Medical, Inc. | February 13, 2023 | 1,091,479 | 10.0% |
| Cellectar Biosciences, Inc. | February 10, 2022 | ? | ? |
| CURIS INC | February 10, 2022 | 3,866,645 | 4.2% |
| Salarius Pharmaceuticals, Inc. | February 10, 2022 | 1,354,291 | 3.0% |
| Larimar Therapeutics, Inc. | February 16, 2021 | 188,661 | 1.2% |
| ACHIEVE LIFE SCIENCES, INC. | February 14, 2020 | ? | ? |
| Bionano Genomics, Inc | February 14, 2020 | 1,210,821 | 4.6% |
| Brickell Biotech, Inc. | February 14, 2020 | ? | ? |
| Trillium Therapeutics Inc. | February 14, 2020 | 2,751,186 | 9.8% |
| ZAFGEN, INC. | February 14, 2020 | 2,283,164 | 6.1% |
View Sio Capital Management, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-12 |
| 13F-HR | 2023-02-13 |
| SC 13G | 2023-02-13 |
| 13F-HR | 2022-11-14 |
View Sio Capital Management, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.