$493 Million is the total value of Sio Capital Management, LLC's 89 reported holdings in Q1 2021. The portfolio turnover from Q4 2020 to Q1 2021 was 49.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CRIS | Sell | CURIS INC | $49,600,000 | +27.3% | 4,381,668 | -7.9% | 10.07% | +26.3% |
| CI | Buy | CIGNA CORP | $25,858,000 | +99.5% | 106,965 | +71.8% | 5.25% | +97.9% |
| CAH | Buy | CARDINAL HEALTH INC | $16,701,000 | +100.9% | 274,917 | +77.1% | 3.39% | +99.2% |
| GLD | Sell | SPDR GOLD SHARES | $15,518,000 | -15.1% | 97,009 | -5.4% | 3.15% | -15.8% |
| SOLY | Sell | SOLITON INC | $14,492,000 | +118.8% | 824,803 | -4.4% | 2.94% | +117.0% |
| CNC | New | CENTENE CORP | $13,900,000 | – | 217,500 | +100.0% | 2.82% | – |
| HCA | Sell | HCA HEALTHCARE INC | $13,781,000 | +3.8% | 73,173 | -9.4% | 2.80% | +2.9% |
| SPRB | Buy | SPRUCE BIOSCIENCES INC | $13,494,000 | -12.8% | 812,884 | +27.7% | 2.74% | -13.5% |
| CHRS | Sell | COHERUS BIOSCIENCES INC | $12,387,000 | -17.5% | 847,862 | -1.9% | 2.51% | -18.2% |
| HRC | Sell | HILL-ROM HOLDINGS INC | $11,893,000 | -1.5% | 107,647 | -12.6% | 2.41% | -2.3% |
| CVM | Sell | CEL-SCI CORPput | $10,582,000 | -57.2% | 695,700 | -67.2% | 2.15% | -57.6% |
| MRK | New | MERCK & CO INC | $9,636,000 | – | 125,000 | +100.0% | 1.96% | – |
| ALBO | Sell | ALBIREO PHARMA INC | $9,459,000 | -28.8% | 268,346 | -24.2% | 1.92% | -29.4% |
| UTHR | Buy | UNITED THERAPEUTICS CORP | $9,374,000 | +59.4% | 56,044 | +44.7% | 1.90% | +58.2% |
| ICLR | New | ICON PLC | $9,328,000 | – | 47,500 | +100.0% | 1.89% | – |
| GSK | New | GLAXOSMITHKLINE PLCsponsored ads | $9,190,000 | – | 257,500 | +100.0% | 1.86% | – |
| AMN | Sell | AMN HEALTHCARE SERVICES INC | $9,131,000 | +2.4% | 123,898 | -5.1% | 1.85% | +1.6% |
| UHS | Sell | UNIVERSAL HEALTH SERVICES INCcl b | $9,089,000 | -18.2% | 68,135 | -15.7% | 1.84% | -18.9% |
| EPIX | Sell | ESSA PHARMA INC | $9,084,000 | +75.8% | 312,711 | -27.8% | 1.84% | +74.5% |
| MIRM | Sell | MIRUM PHARMACEUTICALS INC | $8,664,000 | +0.3% | 437,138 | -11.6% | 1.76% | -0.5% |
| BLRX | New | BIOLINE RX LTDsponsored ads | $7,650,000 | – | 2,741,776 | +100.0% | 1.55% | – |
| MCK | Sell | MCKESSON CORP | $7,586,000 | -8.1% | 38,893 | -18.1% | 1.54% | -8.9% |
| XFOR | New | X4 PHARMACEUTICALS INC | $6,928,000 | – | 804,597 | +100.0% | 1.41% | – |
| HLF | Buy | HERBALIFE NUTRITION LTD | $6,597,000 | +76.8% | 148,719 | +91.5% | 1.34% | +75.3% |
| CHAQ | New | CHARDAN HEALTHCARE ACQUISITION 2 CORP | $6,410,000 | – | 600,000 | +100.0% | 1.30% | – |
| TEVA | Sell | TEVA PHARMACEUTICAL INDUSTRIES LTDsponsored ads | $6,231,000 | -6.5% | 539,947 | -21.8% | 1.26% | -7.3% |
| VAPO | Buy | VAPOTHERM INC | $6,203,000 | +197.2% | 258,261 | +232.4% | 1.26% | +194.8% |
| KURA | Buy | KURA ONCOLOGY INC | $6,035,000 | +39.7% | 213,471 | +61.4% | 1.22% | +38.6% |
| HZNP | Sell | HORIZON THERAPEUTICS PLC | $5,964,000 | -17.6% | 64,801 | -34.5% | 1.21% | -18.2% |
| CCRN | Sell | CROSS COUNTRY HEALTHCARE INC | $5,411,000 | +25.7% | 433,244 | -10.7% | 1.10% | +24.6% |
| AYLA | Buy | AYALA PHARMACEUTICALS INC | $5,346,000 | +210.3% | 489,988 | +212.8% | 1.08% | +207.4% |
| ASLN | Buy | ASLAN PHARMACEUTICALS LTDads | $4,853,000 | +90.4% | 1,448,508 | +4.0% | 0.98% | +88.7% |
| RDUS | Sell | RADIUS HEALTH INC | $4,818,000 | -8.0% | 230,957 | -21.2% | 0.98% | -8.8% |
| ARDX | Buy | ARDELYX INC | $4,771,000 | +7.0% | 720,621 | +4.5% | 0.97% | +6.0% |
| NVAX | New | NOVAVAX INC | $4,660,000 | – | 25,700 | +100.0% | 0.95% | – |
| EBS | New | EMERGENT BIOSOLUTIONS INC | $4,646,000 | – | 50,000 | +100.0% | 0.94% | – |
| SLRX | Buy | SALARIUS PHARMACEUTICALS INC | $4,616,000 | +206.1% | 3,118,696 | +88.2% | 0.94% | +203.2% |
| SYNH | Sell | SYNEOS HEALTH INCcl a | $4,553,000 | +2.8% | 60,025 | -7.7% | 0.92% | +2.0% |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $4,527,000 | -26.9% | 21,067 | -19.6% | 0.92% | -27.5% |
| NTUS | Sell | NATUS MEDICAL INC | $4,340,000 | +15.9% | 169,454 | -9.3% | 0.88% | +15.0% |
| AFMD | New | AFFIMED NV | $4,335,000 | – | 548,044 | +100.0% | 0.88% | – |
| MGNX | New | MACROGENICS INC | $4,141,000 | – | 130,000 | +100.0% | 0.84% | – |
| MBRX | New | MOLECULIN BIOTECH INC | $3,929,000 | – | 963,000 | +100.0% | 0.80% | – |
| CNST | Buy | CONSTELLATION PHARMACEUTICALS INC | $3,887,000 | +45.9% | 166,186 | +79.7% | 0.79% | +44.8% |
| VKTX | Sell | VIKING THERAPEUTICS INC | $3,604,000 | +5.0% | 569,780 | -6.6% | 0.73% | +4.1% |
| CLRB | Sell | CELLECTAR BIOSCIENCES INC | $3,523,000 | -27.3% | 2,188,058 | -6.1% | 0.72% | -28.0% |
| DTIL | Buy | PRECISION BIOSCIENCES INC | $3,409,000 | +28.7% | 329,369 | +3.7% | 0.69% | +27.7% |
| ASGN | Sell | ASGN INC | $3,300,000 | -37.4% | 34,577 | -45.2% | 0.67% | -37.9% |
| SNDX | Sell | SYNDAX PHARMACEUTICALS INC | $3,268,000 | -13.6% | 146,142 | -14.1% | 0.66% | -14.5% |
| AGLE | Buy | AEGLEA BIO THERAPEUTICS INC | $3,189,000 | +112.0% | 402,653 | +110.7% | 0.65% | +110.1% |
| CBIO | Buy | CATALYST BIOSCIENCES INC | $3,144,000 | +164.0% | 623,892 | +230.6% | 0.64% | +161.5% |
| EUCRU | EUCRATES BIOMEDICAL ACQUISITION CORP.unit 10/23/2027 | $3,004,000 | -6.1% | 300,000 | 0.0% | 0.61% | -6.9% | |
| NBSE | Buy | NEUBASE THERAPEUTICS INC | $2,909,000 | +41.7% | 393,699 | +34.0% | 0.59% | +40.5% |
| HSAQ | HEALTH SCIENCES ACQUISITIONS CORP 2 | $2,798,000 | -12.6% | 250,000 | 0.0% | 0.57% | -13.4% | |
| LRMR | Sell | LARIMAR THERAPEUTICS INC | $2,735,000 | -32.3% | 187,223 | -0.8% | 0.56% | -32.9% |
| ONCT | ONCTERNAL THERAPEUTICS INC | $2,690,000 | +69.8% | 323,333 | 0.0% | 0.55% | +68.5% | |
| FUSN | Buy | FUSION PHARMACEUTICALS INC | $2,674,000 | +31.8% | 249,419 | +44.4% | 0.54% | +30.8% |
| PRQR | New | PROQR THERAPEUTICS NV | $2,597,000 | – | 392,821 | +100.0% | 0.53% | – |
| CBAY | Sell | CYMABAY THERAPEUTICS INC | $2,553,000 | -24.3% | 562,339 | -4.3% | 0.52% | -24.9% |
| MRSN | Sell | MERSANA THERAPEUTICS INC | $2,544,000 | -48.3% | 157,259 | -15.0% | 0.52% | -48.8% |
| GOSS | New | GOSSAMER BIO INC | $2,418,000 | – | 261,400 | +100.0% | 0.49% | – |
| FULC | Buy | FULCRUM THERAPEUTICS INC | $2,253,000 | +31.5% | 191,272 | +30.8% | 0.46% | +30.2% |
| VINC | Sell | VINCERX PHARMA INC | $2,027,000 | -35.3% | 105,000 | -29.9% | 0.41% | -36.0% |
| LLY | New | ELI LILLY AND COcall | $1,793,000 | – | 9,600 | +100.0% | 0.36% | – |
| BCEL | Sell | ATRECA INC | $1,739,000 | -16.2% | 113,455 | -11.7% | 0.35% | -16.9% |
| OSMT | New | OSMOTICA PHARMACEUTICALS PLC | $1,692,000 | – | 519,039 | +100.0% | 0.34% | – |
| CERC | Sell | CERECOR INC | $1,668,000 | -31.9% | 552,241 | -40.5% | 0.34% | -32.3% |
| ANIK | Sell | ANIKA THERAPEUTICS INC | $1,632,000 | -44.8% | 40,000 | -38.8% | 0.33% | -45.4% |
| RUBY | New | RUBIUS THERAPEUTICS INC | $1,585,000 | – | 59,800 | +100.0% | 0.32% | – |
| FREQ | New | FREQUENCY THERAPEUTICS INCput | $1,549,000 | – | 163,100 | +100.0% | 0.31% | – |
| ARNA | Sell | ARENA PHARMACEUTICALS INC | $1,508,000 | -66.0% | 21,738 | -62.4% | 0.31% | -66.3% |
| MEIP | MEI PHARMA INC | $1,461,000 | +29.9% | 426,047 | 0.0% | 0.30% | +29.1% | |
| HROW | HARROW HEALTH INC | $1,415,000 | -1.6% | 209,623 | 0.0% | 0.29% | -2.4% | |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $1,407,000 | -43.9% | 44,430 | -17.7% | 0.29% | -44.2% |
| SRRA | Buy | SIERRA ONCOLOGY INC | $1,395,000 | +31.0% | 80,952 | +21.8% | 0.28% | +29.8% |
| AHACU | ALPHA HEALTHCARE ACQUISITION CORPunit 09/21/2027 | $1,250,000 | +18.3% | 100,000 | 0.0% | 0.25% | +17.6% | |
| SIOX | Sell | SIO GENE THERAPIES INC | $1,201,000 | -51.3% | 460,248 | -48.1% | 0.24% | -51.7% |
| ETON | New | ETON PHARMACEUTICALS INC | $1,191,000 | – | 162,659 | +100.0% | 0.24% | – |
| IDYA | IDEAYA BIOSCIENCES INC | $1,135,000 | +67.9% | 48,298 | 0.0% | 0.23% | +66.7% | |
| GLYC | New | GLYCOMIMETICS INC | $1,070,000 | – | 355,517 | +100.0% | 0.22% | – |
| IMAB | I-MABsponsored ads | $727,000 | +2.8% | 15,000 | 0.0% | 0.15% | +2.1% | |
| DFHTU | DEERFIELD HEALTHCARE TECHNOLOGY ACQUISITIONS CORPunit 07/16/2025 | $655,000 | -12.7% | 50,000 | 0.0% | 0.13% | -13.6% | |
| CASI | CASI PHARMACEUTICALS INC | $488,000 | -18.7% | 203,432 | 0.0% | 0.10% | -19.5% | |
| NLTX | NEOLEUKIN THERAPEUTICS INC | $472,000 | -12.6% | 38,312 | 0.0% | 0.10% | -13.5% | |
| MESO | Sell | MESOBLAST LTDput | $468,000 | -86.8% | 56,600 | -86.4% | 0.10% | -86.9% |
| RAPT | RAPT THERAPEUTICS INC | $317,000 | +12.4% | 14,298 | 0.0% | 0.06% | +10.3% | |
| New | APTOSE BIOSCIENCES INC | $246,000 | – | 41,100 | +100.0% | 0.05% | – | |
| BNGO | New | BIONANO GENOMICS INC | $196,000 | – | 24,245 | +100.0% | 0.04% | – |
| TRILLIUM THERAPEUTICS INC | $166,000 | -27.2% | 15,500 | 0.0% | 0.03% | -27.7% | ||
| ZSAN | Exit | ZOSANO PHARMA CORP | $0 | – | -427,542 | -100.0% | -0.05% | – |
| VINCW | Exit | VINCERX PHARMA INC*w exp 12/24/2025 | $0 | – | -210,000 | -100.0% | -0.14% | – |
| ODT | Exit | ODONATE THERAPEUTICS INC | $0 | – | -75,500 | -100.0% | -0.30% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -35,000 | -100.0% | -0.31% | – |
| OTRK | Exit | ONTRAK INC | $0 | – | -38,218 | -100.0% | -0.48% | – |
| CRDF | Exit | CARDIFF ONCOLOGY INC | $0 | – | -149,833 | -100.0% | -0.55% | – |
| VRAY | Exit | VIEWRAY INC | $0 | – | -775,000 | -100.0% | -0.61% | – |
| MED | Exit | MEDIFAST INCput | $0 | – | -18,200 | -100.0% | -0.73% | – |
| ITGR | Exit | INTEGER HOLDINGS CORP | $0 | – | -46,699 | -100.0% | -0.78% | – |
| GWPH | Exit | GW PHARMACEUTICALS PLCads | $0 | – | -33,801 | -100.0% | -0.80% | – |
| MOH | Exit | MOLINA HEALTHCARE INC | $0 | – | -18,763 | -100.0% | -0.82% | – |
| CHAQU | Exit | CHARDAN HEALTHCARE ACQUISITION 2 CORPunit | $0 | – | -400,000 | -100.0% | -0.87% | – |
| VREX | Exit | VAREX IMAGING CORP | $0 | – | -266,740 | -100.0% | -0.91% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -81,026 | -100.0% | -0.94% | – |
| OFIX | Exit | ORTHOFIX MEDICAL INC | $0 | – | -138,525 | -100.0% | -1.22% | – |
| BDX | Exit | BECTON DICKINSON AND CO | $0 | – | -27,314 | -100.0% | -1.40% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -100,844 | -100.0% | -1.81% | – |
| AMGN | Exit | AMGEN INC | $0 | – | -40,000 | -100.0% | -1.88% | – |
| SNY | Exit | SANOFI SAsponsored adr | $0 | – | -220,201 | -100.0% | -2.19% | – |
| WBA | Exit | WALGREENS BOOTS ALLIANCE INC | $0 | – | -308,686 | -100.0% | -2.52% | – |
| ABC | Exit | AMERISOURCEBERGEN CORP | $0 | – | -127,781 | -100.0% | -2.56% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -263,000 | -100.0% | -2.69% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-05-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| VIKING THERAPEUTICS INC | 24 | Q3 2023 | 3.4% |
| UNITED THERAPEUTICS ORD | 23 | Q3 2023 | 8.3% |
| CARDINAL HEALTH ORD | 20 | Q2 2022 | 7.2% |
| SANOFI SA | 19 | Q3 2022 | 9.8% |
| MEDTRONIC PLC | 18 | Q3 2023 | 5.2% |
| CATALYST BIOSCIENCES INC | 18 | Q3 2021 | 17.8% |
| PFENEX ORD | 18 | Q4 2019 | 5.9% |
| AEGLEA BIOTHERAPEUTICS INC | 18 | Q1 2023 | 1.1% |
| HCA HEALTHCARE INC | 17 | Q2 2022 | 5.5% |
| MCKESSON ORD | 17 | Q1 2022 | 6.0% |
View Sio Capital Management, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Modular Medical, Inc. | February 13, 2023 | 1,091,479 | 10.0% |
| Cellectar Biosciences, Inc. | February 10, 2022 | ? | ? |
| CURIS INC | February 10, 2022 | 3,866,645 | 4.2% |
| Salarius Pharmaceuticals, Inc. | February 10, 2022 | 1,354,291 | 3.0% |
| Larimar Therapeutics, Inc. | February 16, 2021 | 188,661 | 1.2% |
| ACHIEVE LIFE SCIENCES, INC. | February 14, 2020 | ? | ? |
| Bionano Genomics, Inc | February 14, 2020 | 1,210,821 | 4.6% |
| Brickell Biotech, Inc. | February 14, 2020 | ? | ? |
| Trillium Therapeutics Inc. | February 14, 2020 | 2,751,186 | 9.8% |
| ZAFGEN, INC. | February 14, 2020 | 2,283,164 | 6.1% |
View Sio Capital Management, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-12 |
| 13F-HR | 2023-02-13 |
| SC 13G | 2023-02-13 |
| 13F-HR | 2022-11-14 |
View Sio Capital Management, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.