$489 Million is the total value of Sio Capital Management, LLC's 89 reported holdings in Q4 2020. The portfolio turnover from Q3 2020 to Q4 2020 was 56.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CRIS | Sell | CURIS INC | $38,955,000 | +572.6% | 4,756,438 | -3.9% | 7.97% | +595.2% |
| CVM | Buy | CEL-SCI CORPput | $24,726,000 | +62.2% | 2,120,600 | +77.4% | 5.06% | +67.6% |
| GLD | Sell | SPDR GOLD SHARES | $18,284,000 | -19.5% | 102,509 | -20.0% | 3.74% | -16.7% |
| SPRB | New | SPRUCE BIOSCIENCES INC | $15,477,000 | – | 636,653 | +100.0% | 3.17% | – |
| CHRS | Sell | COHERUS BIOSCIENCES INC | $15,017,000 | -21.6% | 864,056 | -17.2% | 3.07% | -18.9% |
| ALBO | Sell | ALBIREO PHARMA INC | $13,286,000 | -16.8% | 354,210 | -26.0% | 2.72% | -14.0% |
| HCA | Sell | HCA HEALTHCARE INC | $13,279,000 | +0.5% | 80,745 | -23.8% | 2.72% | +3.9% |
| AZN | New | ASTRAZENECA PLCsponsored adr | $13,147,000 | – | 263,000 | +100.0% | 2.69% | – |
| CI | Sell | CIGNA CORP | $12,962,000 | -6.0% | 62,265 | -23.5% | 2.65% | -2.9% |
| ABC | Sell | AMERISOURCEBERGEN CORP | $12,492,000 | -21.3% | 127,781 | -22.0% | 2.56% | -18.7% |
| WBA | Buy | WALGREENS BOOTS ALLIANCE INC | $12,310,000 | +14.2% | 308,686 | +2.9% | 2.52% | +18.1% |
| HRC | Sell | HILL-ROM HOLDINGS INC | $12,070,000 | -27.7% | 123,198 | -38.4% | 2.47% | -25.3% |
| UHS | New | UNIVERSAL HEALTH SERVICES INCcl b | $11,116,000 | – | 80,843 | +100.0% | 2.28% | – |
| SNY | New | SANOFI SAsponsored adr | $10,700,000 | – | 220,201 | +100.0% | 2.19% | – |
| AMGN | New | AMGEN INC | $9,197,000 | – | 40,000 | +100.0% | 1.88% | – |
| AMN | Sell | AMN HEALTHCARE SERVICES INC | $8,913,000 | -44.0% | 130,598 | -52.0% | 1.82% | -42.1% |
| BMRN | Sell | BIOMARIN PHARMACEUTICAL INC | $8,843,000 | -40.3% | 100,844 | -48.2% | 1.81% | -38.3% |
| MIRM | New | MIRUM PHARMACEUTICALS INC | $8,638,000 | – | 494,743 | +100.0% | 1.77% | – |
| CAH | Sell | CARDINAL HEALTH INC | $8,313,000 | -45.1% | 155,217 | -51.9% | 1.70% | -43.2% |
| MCK | Sell | MCKESSON CORP | $8,255,000 | -53.2% | 47,462 | -59.9% | 1.69% | -51.6% |
| HZNP | Sell | HORIZON THERAPEUTICS PLC | $7,235,000 | -36.9% | 98,901 | -32.9% | 1.48% | -34.7% |
| BDX | Buy | BECTON DICKINSON AND CO | $6,835,000 | +77.3% | 27,314 | +64.8% | 1.40% | +83.1% |
| TEVA | Sell | TEVA PHARMACEUTICAL INDUSTRIES LTDsponsored ads | $6,662,000 | -22.3% | 690,386 | -27.5% | 1.36% | -19.7% |
| SOLY | Sell | SOLITON INC | $6,623,000 | -15.4% | 862,405 | -15.9% | 1.36% | -12.6% |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $6,192,000 | – | 26,200 | +100.0% | 1.27% | – |
| OFIX | Sell | ORTHOFIX MEDICAL INC | $5,954,000 | -12.3% | 138,525 | -36.4% | 1.22% | -9.3% |
| UTHR | Sell | UNITED THERAPEUTICS CORP | $5,879,000 | -1.7% | 38,734 | -34.6% | 1.20% | +1.6% |
| ASGN | New | ASGN INC | $5,269,000 | – | 63,077 | +100.0% | 1.08% | – |
| RDUS | Sell | RADIUS HEALTH INC | $5,236,000 | -33.5% | 293,157 | -57.8% | 1.07% | -31.3% |
| EPIX | Sell | ESSA PHARMA INC | $5,166,000 | +14.1% | 433,023 | -34.0% | 1.06% | +18.0% |
| MRSN | Sell | MERSANA THERAPEUTICS INC | $4,922,000 | -9.4% | 184,959 | -36.6% | 1.01% | -6.3% |
| CLRB | Buy | CELLECTAR BIOSCIENCES INC | $4,849,000 | +186.6% | 2,331,123 | +70.8% | 0.99% | +196.4% |
| IONS | New | IONIS PHARMACEUTICALS INC | $4,581,000 | – | 81,026 | +100.0% | 0.94% | – |
| ARDX | Sell | ARDELYX INC | $4,460,000 | +12.6% | 689,321 | -8.6% | 0.91% | +16.5% |
| VREX | Buy | VAREX IMAGING CORP | $4,449,000 | +203.1% | 266,740 | +131.2% | 0.91% | +213.1% |
| ARNA | Sell | ARENA PHARMACEUTICALS INC | $4,436,000 | -17.3% | 57,738 | -19.5% | 0.91% | -14.6% |
| SYNH | Sell | SYNEOS HEALTH INCcl a | $4,428,000 | -25.2% | 65,000 | -41.6% | 0.91% | -22.6% |
| KURA | Buy | KURA ONCOLOGY INC | $4,320,000 | +350.5% | 132,283 | +322.9% | 0.88% | +365.3% |
| CCRN | Buy | CROSS COUNTRY HEALTHCARE INC | $4,303,000 | +65.2% | 485,164 | +20.9% | 0.88% | +70.7% |
| CHAQU | CHARDAN HEALTHCARE ACQUISITION 2 CORPunit | $4,236,000 | +0.4% | 400,000 | 0.0% | 0.87% | +3.7% | |
| LRMR | Sell | LARIMAR THERAPEUTICS INC | $4,039,000 | -11.4% | 188,661 | -37.2% | 0.83% | -8.4% |
| MOH | Sell | MOLINA HEALTHCARE INC | $3,991,000 | -66.8% | 18,763 | -71.5% | 0.82% | -65.7% |
| GWPH | Buy | GW PHARMACEUTICALS PLCads | $3,901,000 | +95.4% | 33,801 | +64.9% | 0.80% | +102.3% |
| ITGR | Sell | INTEGER HOLDINGS CORP | $3,791,000 | -50.3% | 46,699 | -63.9% | 0.78% | -48.7% |
| SNDX | Buy | SYNDAX PHARMACEUTICALS INC | $3,784,000 | +5229.6% | 170,142 | +3447.6% | 0.78% | +5435.7% |
| NTUS | Buy | NATUS MEDICAL INC | $3,744,000 | +110.5% | 186,833 | +79.9% | 0.77% | +117.6% |
| HLF | Sell | HERBALIFE NUTRITION LTD | $3,732,000 | -9.7% | 77,660 | -12.3% | 0.76% | -6.6% |
| MED | New | MEDIFAST INCput | $3,573,000 | – | 18,200 | +100.0% | 0.73% | – |
| MESO | Sell | MESOBLAST LTDput | $3,543,000 | -87.8% | 417,300 | -73.3% | 0.72% | -87.4% |
| VKTX | Sell | VIKING THERAPEUTICS INC | $3,433,000 | -16.9% | 609,780 | -14.1% | 0.70% | -14.1% |
| CBAY | Sell | CYMABAY THERAPEUTICS INC | $3,371,000 | -59.8% | 587,339 | -49.3% | 0.69% | -58.5% |
| HSAQ | HEALTH SCIENCES ACQUISITIONS CORPORATION 2 | $3,203,000 | +16.5% | 250,000 | 0.0% | 0.66% | +20.4% | |
| EUCRU | New | EUCRATES BIOMEDICAL ACQUISITION CORP.unit 10/23/2027 | $3,198,000 | – | 300,000 | +100.0% | 0.66% | – |
| VINC | New | VINCERX PHARMA INC | $3,134,000 | – | 149,892 | +100.0% | 0.64% | – |
| VRAY | Sell | VIEWRAY INC | $2,961,000 | -58.5% | 775,000 | -62.0% | 0.61% | -57.1% |
| ANIK | Sell | ANIKA THERAPEUTICS INC | $2,959,000 | -11.1% | 65,382 | -30.5% | 0.61% | -8.0% |
| CRDF | New | CARDIFF ONCOLOGY INC | $2,695,000 | – | 149,833 | +100.0% | 0.55% | – |
| CNST | New | CONSTELLATION PHARMACEUTICALS INC | $2,664,000 | – | 92,500 | +100.0% | 0.54% | – |
| DTIL | Sell | PRECISION BIOSCIENCES INC | $2,649,000 | +20.8% | 317,644 | -10.8% | 0.54% | +24.9% |
| ASLN | Buy | ASLAN PHARMACEUTICALS LTDads | $2,549,000 | -2.6% | 1,392,654 | +1.1% | 0.52% | +0.8% |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $2,506,000 | – | 54,000 | +100.0% | 0.51% | – |
| SIOX | New | SIO GENE THERAPIES INC | $2,465,000 | – | 886,665 | +100.0% | 0.50% | – |
| CERC | Sell | CERECOR INC | $2,449,000 | +4.4% | 927,746 | -10.0% | 0.50% | +8.0% |
| OTRK | New | ONTRAK INC | $2,361,000 | – | 38,218 | +100.0% | 0.48% | – |
| VAPO | New | VAPOTHERM INC | $2,087,000 | – | 77,707 | +100.0% | 0.43% | – |
| BCEL | Buy | ATRECA INC | $2,075,000 | +88.6% | 128,455 | +63.1% | 0.42% | +95.0% |
| NBSE | Sell | NEUBASE THERAPEUTICS INC | $2,053,000 | -11.1% | 293,699 | -3.5% | 0.42% | -8.1% |
| FUSN | New | FUSION PHARMACEUTICALS INC | $2,029,000 | – | 172,693 | +100.0% | 0.42% | – |
| AYLA | Sell | AYALA PHARMACEUTICALS INC | $1,723,000 | -6.5% | 156,655 | -2.1% | 0.35% | -3.3% |
| FULC | New | FULCRUM THERAPEUTICS INC | $1,713,000 | – | 146,272 | +100.0% | 0.35% | – |
| ONCT | New | ONCTERNAL THERAPEUTICS INC | $1,584,000 | – | 323,333 | +100.0% | 0.32% | – |
| AGIO | Sell | AGIOS PHARMACEUTICALS INC | $1,517,000 | -22.6% | 35,000 | -37.5% | 0.31% | -19.8% |
| SLRX | New | SALARIUS PHARMACEUTICALS INC | $1,508,000 | – | 1,657,242 | +100.0% | 0.31% | – |
| AGLE | Sell | AEGLEA BIOTHERAPEUTICS INC | $1,504,000 | +0.5% | 191,104 | -9.5% | 0.31% | +4.1% |
| ODT | Sell | ODONATE THERAPEUTICS INC | $1,450,000 | -20.0% | 75,500 | -44.1% | 0.30% | -17.3% |
| HROW | Sell | HARROW HEALTH INC | $1,438,000 | +7.8% | 209,623 | -12.2% | 0.29% | +11.4% |
| CBIO | Sell | CATALYST BIOSCIENCES INC | $1,191,000 | +39.5% | 188,714 | -5.0% | 0.24% | +44.4% |
| MEIP | Sell | MEI PHARMA INC | $1,125,000 | -19.5% | 426,047 | -4.9% | 0.23% | -17.0% |
| SRRA | New | SIERRA ONCOLOGY INC | $1,065,000 | – | 66,455 | +100.0% | 0.22% | – |
| AHACU | ALPHA HEALTHCARE ACQUISITION CORPunit 09/21/2027 | $1,057,000 | +6.6% | 100,000 | 0.0% | 0.22% | +10.2% | |
| DFHTU | DEERFIELD HEALTHCARE TECHNOLOGY ACQUISITIONS CORPunit 07/16/2025 | $750,000 | +41.0% | 50,000 | 0.0% | 0.15% | +46.7% | |
| IMAB | I-MABsponsored ads | $707,000 | +0.3% | 15,000 | 0.0% | 0.14% | +3.6% | |
| VINCW | New | VINCERX PHARMA INC*w exp 12/24/2025 | $693,000 | – | 210,000 | +100.0% | 0.14% | – |
| IDYA | Sell | IDEAYA BIOSCIENCES INC | $676,000 | -2.2% | 48,298 | -12.2% | 0.14% | +0.7% |
| CASI | Sell | CASI PHARMACEUTICALS INC | $600,000 | +74.4% | 203,432 | -9.6% | 0.12% | +80.9% |
| NLTX | NEOLEUKIN THERAPEUTICS INC | $540,000 | +17.4% | 38,312 | 0.0% | 0.11% | +22.0% | |
| RAPT | RAPT THERAPEUTICS INC | $282,000 | -38.7% | 14,298 | 0.0% | 0.06% | -36.3% | |
| New | TRILLIUM THERAPEUTICS INC | $228,000 | – | 15,500 | +100.0% | 0.05% | – | |
| ZSAN | Sell | ZOSANO PHARMA CORP | $225,000 | -69.3% | 427,542 | -5.5% | 0.05% | -68.3% |
| PMVP | Exit | PMV PHARMACEUTICALS INC | $0 | – | -1,000 | -100.0% | -0.01% | – |
| GDRX | Exit | GOODRX HOLDINGS INC | $0 | – | -1,000 | -100.0% | -0.01% | – |
| MYOV | Exit | MYOVANT SCIENCES LTD | $0 | – | -10,100 | -100.0% | -0.03% | – |
| BNGO | Exit | BIONANO GENOMICS INC | $0 | – | -268,096 | -100.0% | -0.03% | – |
| PANAU | Exit | PANACEA ACQUISITION CORPunit | $0 | – | -15,000 | -100.0% | -0.04% | – |
| CRBP | Exit | CORBUS PHARMACEUTICALS HOLDINGS INCput | $0 | – | -556,000 | -100.0% | -0.20% | – |
| SYRS | Exit | SYROS PHARMACEUTICALS INC | $0 | – | -166,780 | -100.0% | -0.29% | – |
| DYAI | Exit | DYADIC INTERNATIONAL INC | $0 | – | -209,064 | -100.0% | -0.31% | – |
| ATNM | Exit | ACTINIUM PHARMACEUTICALS INC | $0 | – | -189,062 | -100.0% | -0.36% | – |
| VNDA | Exit | VANDA PHARMACEUTICALS INC | $0 | – | -209,205 | -100.0% | -0.40% | – |
| OYST | Exit | OYSTER POINT PHARMA INC | $0 | – | -105,803 | -100.0% | -0.44% | – |
| ESPR | Exit | ESPERION THERAPEUTICS INC | $0 | – | -61,600 | -100.0% | -0.45% | – |
| LSACU | Exit | LIFESCI ACQUISITION CORPunit 03/31/2025 | $0 | – | -210,000 | -100.0% | -0.57% | – |
| LPTX | Exit | LEAP THERAPEUTICS INC | $0 | – | -1,451,998 | -100.0% | -0.57% | – |
| AFMD | Exit | AFFIMED NV | $0 | – | -911,279 | -100.0% | -0.61% | – |
| RDNT | Exit | RADNET INC | $0 | – | -223,561 | -100.0% | -0.68% | – |
| MDT | Exit | MEDTRONIC PLC | $0 | – | -39,000 | -100.0% | -0.80% | – |
| QTRX | Exit | QUANTERIX CORP | $0 | – | -124,609 | -100.0% | -0.83% | – |
| ANTM | Exit | ANTHEM INC | $0 | – | -16,031 | -100.0% | -0.85% | – |
| CSII | Exit | CARDIOVASCULAR SYSTEMS INC | $0 | – | -124,808 | -100.0% | -0.97% | – |
| KOD | Exit | KODIAK SCIENCES INC | $0 | – | -92,150 | -100.0% | -1.08% | – |
| GSK | Exit | GLAXOSMITHKLINE PLCsponsored adr | $0 | – | -206,638 | -100.0% | -1.54% | – |
| DGX | Exit | QUEST DIAGNOSTICS INC | $0 | – | -75,000 | -100.0% | -1.70% | – |
| MCRB | Exit | SERES THERAPEUTICS INCput | $0 | – | -316,800 | -100.0% | -1.78% | – |
| JNJ | Exit | JOHNSON & JOHNSON | $0 | – | -114,400 | -100.0% | -3.37% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-02-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| VIKING THERAPEUTICS INC | 24 | Q3 2023 | 3.4% |
| UNITED THERAPEUTICS ORD | 23 | Q3 2023 | 8.3% |
| CARDINAL HEALTH ORD | 20 | Q2 2022 | 7.2% |
| SANOFI SA | 19 | Q3 2022 | 9.8% |
| MEDTRONIC PLC | 18 | Q3 2023 | 5.2% |
| CATALYST BIOSCIENCES INC | 18 | Q3 2021 | 17.8% |
| PFENEX ORD | 18 | Q4 2019 | 5.9% |
| AEGLEA BIOTHERAPEUTICS INC | 18 | Q1 2023 | 1.1% |
| HCA HEALTHCARE INC | 17 | Q2 2022 | 5.5% |
| MCKESSON ORD | 17 | Q1 2022 | 6.0% |
View Sio Capital Management, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Modular Medical, Inc. | February 13, 2023 | 1,091,479 | 10.0% |
| Cellectar Biosciences, Inc. | February 10, 2022 | ? | ? |
| CURIS INC | February 10, 2022 | 3,866,645 | 4.2% |
| Salarius Pharmaceuticals, Inc. | February 10, 2022 | 1,354,291 | 3.0% |
| Larimar Therapeutics, Inc. | February 16, 2021 | 188,661 | 1.2% |
| ACHIEVE LIFE SCIENCES, INC. | February 14, 2020 | ? | ? |
| Bionano Genomics, Inc | February 14, 2020 | 1,210,821 | 4.6% |
| Brickell Biotech, Inc. | February 14, 2020 | ? | ? |
| Trillium Therapeutics Inc. | February 14, 2020 | 2,751,186 | 9.8% |
| ZAFGEN, INC. | February 14, 2020 | 2,283,164 | 6.1% |
View Sio Capital Management, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-12 |
| 13F-HR | 2023-02-13 |
| SC 13G | 2023-02-13 |
| 13F-HR | 2022-11-14 |
View Sio Capital Management, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.