$201 Million is the total value of DAFNA Capital Management LLC's 83 reported holdings in Q4 2018. The portfolio turnover from Q3 2018 to Q4 2018 was 21.3% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| LOXO | Buy | LOXO ONCOLOGY INC | $25,447,000 | -12.2% | 181,675 | +7.1% | 12.65% | +6.3% |
| STXS | STEREOTAXIS INC | $14,789,000 | -10.7% | 13,680,554 | 0.0% | 7.35% | +8.2% | |
| SAGE | Buy | SAGE THERAPEUTICS INC | $9,991,000 | -28.8% | 104,306 | +5.0% | 4.97% | -13.8% |
| ATRC | Buy | ATRICURE INC | $9,753,000 | -5.2% | 318,729 | +8.5% | 4.85% | +14.8% |
| NXTM | Buy | NXSTAGE MEDICAL INC | $8,933,000 | +4.6% | 312,119 | +2.0% | 4.44% | +26.7% |
| IBB | Buy | ISHARES TR NASDAQ BIOTECHetf | $6,258,000 | +96.6% | 64,900 | +148.7% | 3.11% | +138.1% |
| ARGX | Sell | ARGENX SEsponsored adr | $5,601,000 | +14.8% | 58,300 | -9.3% | 2.78% | +39.0% |
| ZGNX | Buy | ZOGENIX INC | $5,242,000 | -23.6% | 143,764 | +4.0% | 2.61% | -7.4% |
| AERI | Buy | AERIE PHARMACEUTICALS INC | $5,118,000 | -37.4% | 141,770 | +6.8% | 2.54% | -24.2% |
| BPMC | BLUEPRINT MEDICINES CORP | $4,997,000 | -30.9% | 92,691 | 0.0% | 2.48% | -16.4% | |
| ASND | ASCENDIS PHARMA A Ssponsored adr | $4,839,000 | -11.6% | 77,242 | 0.0% | 2.41% | +7.1% | |
| PRQR | Buy | PROQR THERAPEUTICS N V | $4,300,000 | -14.6% | 272,474 | +4.7% | 2.14% | +3.3% |
| DXCM | Sell | DEXCOM INC | $4,073,000 | -23.0% | 34,000 | -8.1% | 2.02% | -6.8% |
| ALDR | ALDER BIOPHARMACEUTICALS INC | $4,059,000 | -38.4% | 396,013 | 0.0% | 2.02% | -25.5% | |
| AKBA | Buy | AKEBIA THERAPEUTICS INC | $3,957,000 | -28.4% | 715,538 | +14.4% | 1.97% | -13.3% |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $3,928,000 | -22.1% | 55,008 | +34.1% | 1.95% | -5.7% |
| GLPG | Buy | GALAPAGOS NVspon adr | $3,817,000 | -14.3% | 41,609 | +5.0% | 1.90% | +3.8% |
| BCRX | Sell | BIOCRYST PHARMACEUTICALS INC | $3,748,000 | -24.7% | 464,415 | -28.8% | 1.86% | -8.8% |
| ARNA | Sell | ARENA PHARMACEUTICALS INC | $3,659,000 | -19.3% | 93,942 | -4.7% | 1.82% | -2.3% |
| Sell | INTEC PHARMA LTD JERUSALEM | $3,493,000 | +15.1% | 463,228 | -13.7% | 1.74% | +39.4% | |
| LMNX | LUMINEX CORP | $3,198,000 | -23.8% | 138,391 | 0.0% | 1.59% | -7.7% | |
| RADIUS HEALTH INCnote 3.000% 9/0 | $3,064,000 | -0.5% | 4,000,000 | 0.0% | 1.52% | +20.5% | ||
| BHVN | Buy | BIOHAVEN PHARMACEUTICALS HOLD | $2,958,000 | +162.5% | 80,000 | +166.7% | 1.47% | +217.7% |
| FOMX | FOAMIX PHARMACEUTICALS LTD | $2,901,000 | -37.3% | 808,000 | 0.0% | 1.44% | -24.1% | |
| BLUE | Buy | BLUEBIRD BIO INC | $2,678,000 | -10.5% | 27,000 | +31.7% | 1.33% | +8.4% |
| CBAY | Buy | CYMABAY THERAPEUTICS INC | $2,617,000 | -19.8% | 332,511 | +12.9% | 1.30% | -2.9% |
| BEAT | Sell | BIOTELEMETRY INC | $2,556,000 | -15.3% | 42,800 | -8.5% | 1.27% | +2.7% |
| MNLO | Buy | MENLO THERAPEUTICS INC | $2,227,000 | -27.5% | 540,637 | +73.3% | 1.11% | -12.3% |
| KURA | Sell | KURA ONCOLOGY INC | $2,087,000 | -50.4% | 148,617 | -38.2% | 1.04% | -39.9% |
| WVE | WAVE LIFE SCIENCES LTD | $2,014,000 | -15.9% | 47,900 | 0.0% | 1.00% | +1.9% | |
| CSII | Buy | CARDIOVASCULAR SYSTEMS INC | $1,886,000 | -14.3% | 66,200 | +17.8% | 0.94% | +3.9% |
| CARA | Buy | CARA THERAPEUTICS INC | $1,867,000 | -30.9% | 143,611 | +27.3% | 0.93% | -16.4% |
| TBIO | Buy | TRANSLATE BIO INC | $1,717,000 | +13.2% | 228,939 | +50.9% | 0.85% | +37.1% |
| INSULET CORPnote 1.375% | $1,590,000 | -16.7% | 1,500,000 | 0.0% | 0.79% | +0.9% | ||
| XENE | XENON PHARMACEUTICALS INC | $1,500,000 | -52.2% | 237,683 | 0.0% | 0.75% | -42.1% | |
| VKTX | New | VIKING THERAPEUTICS INC | $1,371,000 | – | 179,200 | +100.0% | 0.68% | – |
| INCY | INCYTE CORP | $1,367,000 | -7.9% | 21,500 | 0.0% | 0.68% | +11.5% | |
| VBIV | Sell | VBI VACCINES INC | $1,360,000 | -39.9% | 850,000 | -9.1% | 0.68% | -27.2% |
| CNCE | New | CONCERT PHARMACEUTICALS INC | $1,326,000 | – | 105,656 | +100.0% | 0.66% | – |
| NTUS | NATUS MEDICAL INC | $1,290,000 | -4.5% | 37,900 | 0.0% | 0.64% | +15.5% | |
| ARQL | Buy | ARQULE INC | $1,268,000 | -50.0% | 457,664 | +2.2% | 0.63% | -39.4% |
| DRNA | DICERNA PHARMACEUTICALS INC | $1,267,000 | -29.9% | 118,500 | 0.0% | 0.63% | -15.1% | |
| NVRO | New | NEVRO CORP | $1,214,000 | – | 31,210 | +100.0% | 0.60% | – |
| JNJ | JOHNSON AND JOHNSON | $1,213,000 | -6.6% | 9,400 | 0.0% | 0.60% | +13.1% | |
| IMMU | Sell | IMMUNOMEDICS INC | $1,174,000 | -68.3% | 82,254 | -53.8% | 0.58% | -61.7% |
| CYTK | Buy | CYTOKINETICS INC | $1,174,000 | +90.3% | 185,826 | +196.4% | 0.58% | +130.8% |
| ASMB | Buy | ASSEMBLY BIOSCIENCES INC | $1,144,000 | +188.9% | 50,573 | +373.8% | 0.57% | +249.1% |
| ACHN | Sell | ACHILLION PHARMACEUTICALS | $1,002,000 | -67.9% | 630,182 | -25.7% | 0.50% | -61.1% |
| MGNX | MACROGENICS INC | $994,000 | -40.8% | 78,305 | 0.0% | 0.49% | -28.3% | |
| ABUS | New | ARBUTUS BIOPHARMA CORP | $946,000 | – | 246,900 | +100.0% | 0.47% | – |
| CRBP | New | CORBUS PHARMACEUTICALS HLDGS | $905,000 | – | 155,000 | +100.0% | 0.45% | – |
| AGTC | Sell | APPLIED GENETIC TECHNOL CORP | $894,000 | -66.0% | 359,190 | -0.2% | 0.44% | -58.8% |
| ARDX | ARDELYX INC | $846,000 | -58.9% | 472,859 | 0.0% | 0.42% | -50.2% | |
| MDGL | New | MADRIGAL PHARMACEUTICALS INC | $744,000 | – | 6,600 | +100.0% | 0.37% | – |
| URGN | UROGEN PHARMA LTD | $646,000 | -8.8% | 15,000 | 0.0% | 0.32% | +10.3% | |
| SCYX | SCYNEXIS INC | $613,000 | -59.9% | 1,272,927 | 0.0% | 0.30% | -51.4% | |
| OBSV | Buy | OBSEVA SA | $561,000 | -28.2% | 44,338 | +2.3% | 0.28% | -13.1% |
| CDTX | CIDARA THERAPEUTICS INC | $500,000 | -46.6% | 212,766 | 0.0% | 0.25% | -35.2% | |
| SPRO | SPERO THERAPEUTICS INC | $431,000 | -41.4% | 70,000 | 0.0% | 0.21% | -29.1% | |
| VLRX | New | VALERITAS HOLDINGS INC | $431,000 | – | 1,325,000 | +100.0% | 0.21% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $415,000 | – | 50,000 | +100.0% | 0.21% | – |
| KALV | Buy | KALVISTA PHARMACEUTICALS INC | $399,000 | +1.8% | 20,225 | +14.1% | 0.20% | +23.0% |
| ZFGN | Sell | ZAFGEN INC | $358,000 | -64.3% | 72,279 | -15.8% | 0.18% | -56.8% |
| LPTX | Buy | LEAP THERPEUTICS INC | $340,000 | -69.0% | 170,000 | +20.9% | 0.17% | -62.4% |
| RDUS | RADIUS HEALTH INC | $338,000 | -7.4% | 20,500 | 0.0% | 0.17% | +12.0% | |
| DEXCOM INCnote 0.750% 5/1 | $336,000 | -12.3% | 250,000 | 0.0% | 0.17% | +6.4% | ||
| ARCT | New | ARCTURUS THERAPEUTICS LTD | $330,000 | – | 72,805 | +100.0% | 0.16% | – |
| MASI | MASIMO CORPORATION | $322,000 | -13.9% | 3,000 | 0.0% | 0.16% | +3.9% | |
| ADXS | ADVAXIS INC | $317,000 | -79.8% | 1,666,666 | 0.0% | 0.16% | -75.4% | |
| RIGL | RIGEL PHARMACEUTICALS INC | $316,000 | -28.5% | 137,600 | 0.0% | 0.16% | -13.7% | |
| PHAS | New | PHASEBIO PHARMACEUTICALS INC | $309,000 | – | 100,000 | +100.0% | 0.15% | – |
| STRO | Buy | SUTRO BIOPHARMA INC | $284,000 | -31.1% | 31,494 | +14.5% | 0.14% | -16.6% |
| APTX | APTINYX INC | $240,000 | -42.9% | 14,500 | 0.0% | 0.12% | -30.8% | |
| SLGL | SOL GEL TECHNOLOGIES LTD | $211,000 | -19.8% | 35,000 | 0.0% | 0.10% | -2.8% | |
| ALDER BIOPHARMACEUTICALS INCnote 2.500% 2/0 | $201,000 | -25.3% | 250,000 | 0.0% | 0.10% | -9.1% | ||
| PTI | New | PROTEOSTASIS THERAPEUTICS INC | $177,000 | – | 54,569 | +100.0% | 0.09% | – |
| NERV | Sell | MINERVA NEUROSCIENCES INC | $176,000 | -47.9% | 26,084 | -3.1% | 0.09% | -36.7% |
| KDMN | Buy | KADMON HOLDINGS INC | $136,000 | -35.2% | 65,500 | +4.0% | 0.07% | -20.9% |
| BTX | BIOTIME INC | $91,000 | -61.3% | 100,000 | 0.0% | 0.04% | -53.6% | |
| BLCM | BELLICUM PHARMACEUTICALS INC | $88,000 | -52.4% | 30,000 | 0.0% | 0.04% | -42.1% | |
| DERM | Buy | DERMIRA INC | $72,000 | +30.9% | 10,000 | +100.0% | 0.04% | +56.5% |
| ORMP | New | ORAMED PHARMACEUTICALS INC | $48,000 | – | 16,000 | +100.0% | 0.02% | – |
| NEOS | NEOS THERAPEUTICS INC | $45,000 | -66.2% | 27,500 | 0.0% | 0.02% | -60.0% | |
| NTGN | Exit | NEON THERAPEUICS INC | $0 | – | -50,000 | -100.0% | -0.18% | – |
| SNSS | Exit | SUNESIS PHARMACEUTICALS INC | $0 | – | -373,702 | -100.0% | -0.31% | – |
| IMDZ | Exit | IMMUNE DESIGN CORP | $0 | – | -328,500 | -100.0% | -0.46% | – |
| NVAX | Exit | NOVAVAX INC | $0 | – | -700,000 | -100.0% | -0.54% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2019-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| STEREOTAXIS INC | 42 | Q3 2023 | 27.6% |
| ATRICURE INC | 42 | Q3 2023 | 11.4% |
| MASIMO CORPORATION | 42 | Q3 2023 | 1.8% |
| ASCENDIS PHARMA A S SPONSORED | 34 | Q3 2023 | 4.5% |
| AERIE PHARMACEUTICALS INC | 33 | Q3 2022 | 4.2% |
| GALAPAGOS NV-SPON ADR | 33 | Q3 2023 | 3.8% |
| XENON PHARMACEUTICALS INC | 33 | Q3 2023 | 3.6% |
| NEUROCRINE BIOSCIENCES INC | 32 | Q3 2023 | 2.9% |
| JOHNSON AND JOHNSON | 32 | Q1 2021 | 1.2% |
| ISHARES TR NASDQ BIOTECH | 30 | Q3 2023 | 4.0% |
View DAFNA Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Stereotaxis, Inc. | March 08, 2018 | 13,680,554 | 23.4% |
| SUNESIS PHARMACEUTICALS INC | February 14, 2018 | 983,000 | 2.9% |
| SUNESIS PHARMACEUTICALS INC | February 14, 2017 | 1,133,583 | 5.4% |
| WINDTREE THERAPEUTICS INC /DE/ | February 14, 2017 | 208,333 | 2.4% |
| ANAVEX LIFE SCIENCES CORP.Sold out | February 16, 2016 | 0 | 0.0% |
| DISCOVERY LABORATORIES INC /DE/ | February 16, 2016 | 10,658,699 | 9.2% |
| PRECISION OPTICS CORPORATION, INC. | February 13, 2015 | 311,537 | 5.0% |
| TearLab Corp | February 14, 2013 | 939,239 | 3.2% |
| VIKING SYSTEMS INC | February 14, 2012 | 3,781,468 | 5.2% |
View DAFNA Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| SC 13G/A | 2023-02-14 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-14 |
| 13F-HR | 2022-08-15 |
View DAFNA Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.