$510 Million is the total value of GREAT POINT PARTNERS LLC's 42 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 80.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PCVX | Buy | VAXCYTE INC | $38,360,000 | +166.4% | 800,000 | +33.3% | 7.52% | +116.9% |
| XENE | XENON PHARMACEUTICALS INC | $33,515,500 | +9.2% | 850,000 | 0.0% | 6.57% | -11.1% | |
| RAPT | Buy | RAPT THERAPEUTICS INC | $28,444,066 | +275.3% | 1,436,569 | +356.1% | 5.58% | +205.5% |
| ALPN | Buy | ALPINE IMMUNE SCIENCES INC | $26,737,227 | +7.7% | 3,637,718 | +5.5% | 5.24% | -12.3% |
| PLRX | Buy | PLIANT THERAPEUTICS INC | $25,571,077 | +17.5% | 1,322,870 | +27.0% | 5.01% | -4.4% |
| JAZZ | Sell | JAZZ PHARMACEUTICALS PLC | $25,489,600 | -11.1% | 160,000 | -25.6% | 5.00% | -27.6% |
| SGEN | Buy | SEAGEN INC | $20,625,855 | +97.1% | 160,500 | +109.8% | 4.04% | +60.4% |
| PNT | Sell | POINT BIOPHARMA GLOBAL INC | $18,529,569 | -32.7% | 2,541,779 | -28.6% | 3.63% | -45.2% |
| NVCR | New | NOVOCURE LTDput | $17,677,350 | – | 241,000 | +100.0% | 3.46% | – |
| ISEE | New | IVERIC BIO INC | $17,663,250 | – | 825,000 | +100.0% | 3.46% | – |
| ACRS | ACLARIS THERAPEUTICS INC | $16,053,692 | +0.1% | 1,019,282 | 0.0% | 3.15% | -18.5% | |
| HRTX | Buy | HERON THERAPEUTICS INC | $15,900,403 | -32.3% | 6,360,161 | +12.7% | 3.12% | -44.9% |
| RARE | New | ULTRAGENYX PHARMACEUTICAL IN | $15,858,759 | – | 342,300 | +100.0% | 3.11% | – |
| OPTN | New | OPTINOSE INC | $14,605,262 | – | 7,894,736 | +100.0% | 2.86% | – |
| Buy | VENTYX BIOSCIENCES INC | $13,138,789 | +39.4% | 400,695 | +48.4% | 2.58% | +13.5% | |
| Buy | CINCOR PHARMA INC | $12,525,390 | +26.7% | 1,019,153 | +238.2% | 2.46% | +3.1% | |
| VKTX | New | VIKING THERAPEUTICS INC | $12,173,320 | – | 1,295,034 | +100.0% | 2.39% | – |
| DAWN | Buy | DAY ONE BIOPHARMACEUTICALS I | $11,716,586 | +728.0% | 544,451 | +670.9% | 2.30% | +573.6% |
| PTCT | New | PTC THERAPEUTICS INC | $11,532,493 | – | 302,135 | +100.0% | 2.26% | – |
| AVTE | New | AEROVATE THERAPEUTICS INC | $11,090,695 | – | 378,522 | +100.0% | 2.17% | – |
| TVTX | Sell | TRAVERE THERAPEUTICS INC | $9,989,250 | -58.0% | 475,000 | -50.8% | 1.96% | -65.8% |
| CBAY | Buy | CYMABAY THERAPEUTICS INC | $9,718,500 | +247.3% | 1,550,000 | +93.9% | 1.90% | +182.6% |
| SRPT | New | SAREPTA THERAPEUTICS INC | $9,459,340 | – | 73,000 | +100.0% | 1.85% | – |
| RCKT | New | ROCKET PHARMACEUTICALS INCcall | $8,826,070 | – | 451,000 | +100.0% | 1.73% | – |
| KALV | Sell | KALVISTA PHARMACEUTICALS INC | $7,137,215 | -68.3% | 1,055,801 | -32.0% | 1.40% | -74.2% |
| New | AMYLYX PHARMACEUTICALS INC | $7,020,500 | – | 190,000 | +100.0% | 1.38% | – | |
| Buy | MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $6,746,943 | +76.7% | 642,566 | +30.6% | 1.32% | +43.9% | |
| New | ERASCA INC | $6,630,767 | – | 1,538,461 | +100.0% | 1.30% | – | |
| ICPT | Buy | INTERCEPT PHARMACEUTICALS IN | $6,541,875 | +346.5% | 528,850 | +403.7% | 1.28% | +263.2% |
| ABOS | Sell | ACUMEN PHARMACEUTICALS INC | $6,029,537 | -49.9% | 1,116,581 | -7.0% | 1.18% | -59.2% |
| MRTX | New | MIRATI THERAPEUTICS INC | $6,026,230 | – | 133,000 | +100.0% | 1.18% | – |
| VERV | New | VERVE THERAPEUTICS INC | $5,805,000 | – | 300,000 | +100.0% | 1.14% | – |
| ALBO | New | ALBIREO PHARMA INC | $5,775,986 | – | 267,283 | +100.0% | 1.13% | – |
| LRMR | Buy | LARIMAR THERAPEUTICS INC | $5,260,113 | +44.8% | 1,273,635 | +12.2% | 1.03% | +17.8% |
| URGN | Sell | UROGEN PHARMA LTD | $4,967,200 | -31.6% | 560,000 | -35.9% | 0.97% | -44.3% |
| DTIL | Buy | PRECISION BIOSCIENCES INC | $4,523,553 | +28.4% | 3,801,305 | +40.2% | 0.89% | +4.5% |
| GRCL | Buy | GRACELL BIOTECHNOLOGIES INCsponsored ads | $4,513,518 | +212.1% | 1,962,399 | +337.0% | 0.88% | +154.3% |
| GBIO | Buy | GENERATION BIO CO | $4,018,570 | -8.3% | 1,022,537 | +23.9% | 0.79% | -25.3% |
| EOLS | New | EVOLUS INC | $1,429,371 | – | 190,329 | +100.0% | 0.28% | – |
| ALKS | Sell | ALKERMES PLC | $1,206,814 | -89.4% | 46,185 | -90.9% | 0.24% | -91.3% |
| IMUX | New | IMMUNIC INC | $885,058 | – | 632,184 | +100.0% | 0.17% | – |
| ANAB | New | ANAPTYSBIO INC | $464,850 | – | 15,000 | +100.0% | 0.09% | – |
| SLN | Exit | SILENCE THERAPEUTICS PLCads | $0 | – | -68,915 | -100.0% | -0.17% | – |
| AGLE | Exit | AEGLEA BIOTHERAPEUTICS INC | $0 | – | -2,500,000 | -100.0% | -0.32% | – |
| NKTR | Exit | NEKTAR THERAPEUTICS | $0 | – | -447,820 | -100.0% | -0.34% | – |
| MGTA | Exit | MAGENTA THERAPEUTICS INC | $0 | – | -1,019,091 | -100.0% | -0.35% | – |
| PIRS | Exit | PIERIS PHARMACEUTICALS INC | $0 | – | -1,965,449 | -100.0% | -0.54% | – |
| IMCR | Exit | IMMUNOCORE HLDGS PLCads | $0 | – | -78,527 | -100.0% | -0.89% | – |
| NGM | Exit | NGM BIOPHARMACEUTICALS INC | $0 | – | -316,256 | -100.0% | -1.00% | – |
| ETNB | Exit | 89BIO INC | $0 | – | -955,000 | -100.0% | -1.33% | – |
| MIST | Exit | MILESTONE PHARMACEUTICALS IN | $0 | – | -674,656 | -100.0% | -1.49% | – |
| MDGL | Exit | MADRIGAL PHARMACEUTICALS INC | $0 | – | -95,500 | -100.0% | -1.50% | – |
| REPL | Exit | REPLIMUNE GROUP INC | $0 | – | -390,000 | -100.0% | -1.62% | – |
| TCDA | Exit | TRICIDA INC | $0 | – | -870,000 | -100.0% | -2.20% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INC | $0 | – | -1,050,000 | -100.0% | -2.51% | – |
| GLPG | Exit | GALAPAGOS NVspon adr | $0 | – | -306,411 | -100.0% | -3.15% | – |
| RLMD | Exit | RELMADA THERAPEUTICS INC | $0 | – | -510,000 | -100.0% | -4.55% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| STREAMLINE HEALTH SOLUTNS, INC CMN | 25 | Q3 2019 | 2.5% |
| IOVANCE BIOTHERAPEUTICS, INC. CMN | 16 | Q1 2021 | 14.3% |
| ZOGENIX INC CMN | 16 | Q4 2019 | 8.8% |
| PTC THERAPEUTICS, INC. CMN | 16 | Q3 2023 | 9.9% |
| EXELIXIS, INC | 16 | Q1 2022 | 7.5% |
| SAGE THERAPEUTICS, INC CMN | 15 | Q3 2021 | 10.8% |
| CYTOKINETICS INC | 15 | Q3 2023 | 5.8% |
| ACADIA PHARMACEUTICALS, INC. | 14 | Q1 2021 | 8.8% |
| ACCELERON PHARMA INC CMN | 14 | Q2 2020 | 8.2% |
| CONNECTURE INC | 13 | Q4 2017 | 25.1% |
View GREAT POINT PARTNERS LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| 89bio, Inc. | February 14, 2023 | 700,000 | 1.4% |
| KalVista Pharmaceuticals, Inc. | February 14, 2023 | 1,055,801 | 3.1% |
| Avalo Therapeutics, Inc. | February 13, 2023 | 974,639 | 7.1% |
| InflaRx N.V.Sold out | February 14, 2022 | 0 | 0.0% |
| ABEONA THERAPEUTICS INC.Sold out | February 16, 2021 | 0 | 0.0% |
| CONSTELLATION PHARMACEUTICALS INC | February 16, 2021 | 1,024,800 | 2.2% |
| GERON CORP | February 16, 2021 | 12,754,228 | 4.0% |
| Millendo Therapeutics, Inc. | February 16, 2021 | 270,000 | 1.4% |
| NextCure, Inc.Sold out | February 16, 2021 | 0 | 0.0% |
| PROTHENA CORP PUBLIC LTD CO | February 16, 2021 | 977,647 | 2.4% |
View GREAT POINT PARTNERS LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-04-08 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View GREAT POINT PARTNERS LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.