$509 Million is the total value of GREAT POINT PARTNERS LLC's 44 reported holdings in Q1 2023. The portfolio turnover from Q4 2022 to Q1 2023 was 71.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PLRX | Sell | PLIANT THERAPEUTICS INC | $32,241,754 | +26.1% | 1,212,096 | -8.4% | 6.33% | +26.3% |
| XENE | Sell | XENON PHARMACEUTICALS INC | $29,294,294 | -12.6% | 818,505 | -3.7% | 5.75% | -12.4% |
| ALPN | Buy | ALPINE IMMUNE SCIENCES INC | $28,878,675 | +8.0% | 3,740,761 | +2.8% | 5.67% | +8.2% |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $27,164,783 | +71.3% | 677,426 | +97.9% | 5.33% | +71.6% |
| RAPT | Sell | RAPT THERAPEUTICS INC | $24,867,021 | -12.6% | 1,355,151 | -5.7% | 4.88% | -12.4% |
| PCVX | Sell | VAXCYTE INC | $24,707,228 | -35.6% | 659,211 | -17.6% | 4.85% | -35.5% |
| PNT | Buy | POINT BIOPHARMA GLOBAL INC | $24,594,621 | +32.7% | 3,383,029 | +33.1% | 4.83% | +33.0% |
| Buy | AMYLYX PHARMACEUTICALS INC | $22,996,545 | +227.6% | 783,795 | +312.5% | 4.52% | +228.1% | |
| TVTX | Buy | TRAVERE THERAPEUTICS INC | $22,557,470 | +125.8% | 1,003,000 | +111.2% | 4.43% | +126.2% |
| JAZZ | Sell | JAZZ PHARMACEUTICALS PLC | $21,876,335 | -14.2% | 149,500 | -6.6% | 4.30% | -14.0% |
| EOLS | Buy | EVOLUS INC | $18,551,223 | +1197.9% | 2,192,816 | +1052.1% | 3.64% | +1200.7% |
| CYTK | New | CYTOKINETICS INC | $17,595,000 | – | 500,000 | +100.0% | 3.46% | – |
| ANAB | Buy | ANAPTYSBIO INC | $17,502,286 | +3665.1% | 804,333 | +5262.2% | 3.44% | +3675.8% |
| ISEE | Sell | IVERIC BIO INC | $16,885,239 | -4.4% | 694,009 | -15.9% | 3.32% | -4.2% |
| VKTX | Sell | VIKING THERAPEUTICS INC | $16,650,000 | +36.8% | 1,000,000 | -22.8% | 3.27% | +37.0% |
| AVTE | Buy | AEROVATE THERAPEUTICS INC | $15,240,855 | +37.4% | 755,620 | +99.6% | 2.99% | +37.6% |
| OPTN | OPTINOSE INC | $15,236,840 | +4.3% | 7,894,736 | 0.0% | 2.99% | +4.5% | |
| IMCR | New | IMMUNOCORE HLDGS PLCads | $12,625,344 | – | 255,367 | +100.0% | 2.48% | – |
| KALV | Buy | KALVISTA PHARMACEUTICALS INC | $12,580,284 | +76.3% | 1,600,545 | +51.6% | 2.47% | +76.6% |
| RLAY | New | RELAY THERAPEUTICS INC | $10,839,352 | – | 658,127 | +100.0% | 2.13% | – |
| New | MINERALYS THERAPEUTICS INC | $9,714,305 | – | 620,326 | +100.0% | 1.91% | – | |
| ACRS | Buy | ACLARIS THERAPEUTICS INC | $9,639,890 | -40.0% | 1,191,581 | +16.9% | 1.89% | -39.8% |
| HRTX | Sell | HERON THERAPEUTICS INC | $8,784,226 | -44.8% | 5,817,368 | -8.5% | 1.72% | -44.7% |
| New | ARCELLX INC | $7,918,355 | – | 257,006 | +100.0% | 1.56% | – | |
| DTIL | Buy | PRECISION BIOSCIENCES INC | $6,104,009 | +34.9% | 8,099,799 | +113.1% | 1.20% | +35.1% |
| Sell | MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $5,953,564 | -11.8% | 278,334 | -56.7% | 1.17% | -11.6% | |
| GRCL | Buy | GRACELL BIOTECHNOLOGIES INCsponsored ads | $5,864,963 | +29.9% | 3,153,206 | +60.7% | 1.15% | +30.2% |
| CBAY | Sell | CYMABAY THERAPEUTICS INC | $4,425,400 | -54.5% | 507,500 | -67.3% | 0.87% | -54.4% |
| GBIO | GENERATION BIO CO | $4,396,909 | +9.4% | 1,022,537 | 0.0% | 0.86% | +9.5% | |
| ABOS | Sell | ACUMEN PHARMACEUTICALS INC | $4,268,144 | -29.2% | 1,051,267 | -5.8% | 0.84% | -29.1% |
| FOLD | New | AMICUS THERAPEUTICS INC | $4,214,200 | – | 380,000 | +100.0% | 0.83% | – |
| LRMR | Sell | LARIMAR THERAPEUTICS INC | $4,077,000 | -22.5% | 900,000 | -29.3% | 0.80% | -22.4% |
| ITCI | New | INTRA-CELLULAR THERAPIES INC | $3,810,590 | – | 70,371 | +100.0% | 0.75% | – |
| ETNB | New | 89BIO INC | $3,807,500 | – | 250,000 | +100.0% | 0.75% | – |
| ACRS | New | ACLARIS THERAPEUTICS INCcall | $2,022,500 | – | 250,000 | +100.0% | 0.40% | – |
| KMPH | New | ZEVRA THERAPEUTICS INC | $1,913,032 | – | 347,824 | +100.0% | 0.38% | – |
| DAWN | Sell | DAY ONE BIOPHARMACEUTICALS I | $1,892,203 | -83.9% | 141,526 | -74.0% | 0.37% | -83.8% |
| RYTM | New | RHYTHM PHARMACEUTICALS INC | $1,740,185 | – | 97,544 | +100.0% | 0.34% | – |
| PRAX | New | PRAXIS PRECISION MEDICINES I | $1,644,333 | – | 2,032,550 | +100.0% | 0.32% | – |
| VKTX | New | VIKING THERAPEUTICS INCput | $1,332,000 | – | 80,000 | +100.0% | 0.26% | – |
| New | SOLID BIOSCIENCES INC | $997,320 | – | 210,405 | +100.0% | 0.20% | – | |
| New | AVALO THERAPEUTICS INC | $830,618 | – | 474,639 | +100.0% | 0.16% | – | |
| RPHM | New | RENEO PHARMACEUTICALS INC | $722,767 | – | 120,864 | +100.0% | 0.14% | – |
| URGN | Sell | UROGEN PHARMA LTD | $362,411 | -92.7% | 39,222 | -93.0% | 0.07% | -92.7% |
| IMUX | Exit | IMMUNIC INC | $0 | – | -632,184 | -100.0% | -0.17% | – |
| ALKS | Exit | ALKERMES PLC | $0 | – | -46,185 | -100.0% | -0.24% | – |
| ALBO | Exit | ALBIREO PHARMA INC | $0 | – | -267,283 | -100.0% | -1.13% | – |
| VERV | Exit | VERVE THERAPEUTICS INC | $0 | – | -300,000 | -100.0% | -1.14% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -133,000 | -100.0% | -1.18% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS IN | $0 | – | -528,850 | -100.0% | -1.28% | – |
| Exit | ERASCA INC | $0 | – | -1,538,461 | -100.0% | -1.30% | – | |
| RCKT | Exit | ROCKET PHARMACEUTICALS INCcall | $0 | – | -451,000 | -100.0% | -1.73% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -73,000 | -100.0% | -1.85% | – |
| PTCT | Exit | PTC THERAPEUTICS INC | $0 | – | -302,135 | -100.0% | -2.26% | – |
| Exit | CINCOR PHARMA INC | $0 | – | -1,019,153 | -100.0% | -2.46% | – | |
| Exit | VENTYX BIOSCIENCES INC | $0 | – | -400,695 | -100.0% | -2.58% | – | |
| NVCR | Exit | NOVOCURE LTDput | $0 | – | -241,000 | -100.0% | -3.46% | – |
| SGEN | Exit | SEAGEN INC | $0 | – | -160,500 | -100.0% | -4.04% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-05-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| STREAMLINE HEALTH SOLUTNS, INC CMN | 25 | Q3 2019 | 2.5% |
| IOVANCE BIOTHERAPEUTICS, INC. CMN | 16 | Q1 2021 | 14.3% |
| ZOGENIX INC CMN | 16 | Q4 2019 | 8.8% |
| PTC THERAPEUTICS, INC. CMN | 16 | Q3 2023 | 9.9% |
| EXELIXIS, INC | 16 | Q1 2022 | 7.5% |
| SAGE THERAPEUTICS, INC CMN | 15 | Q3 2021 | 10.8% |
| CYTOKINETICS INC | 15 | Q3 2023 | 5.8% |
| ACADIA PHARMACEUTICALS, INC. | 14 | Q1 2021 | 8.8% |
| ACCELERON PHARMA INC CMN | 14 | Q2 2020 | 8.2% |
| CONNECTURE INC | 13 | Q4 2017 | 25.1% |
View GREAT POINT PARTNERS LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| 89bio, Inc. | February 14, 2023 | 700,000 | 1.4% |
| KalVista Pharmaceuticals, Inc. | February 14, 2023 | 1,055,801 | 3.1% |
| Avalo Therapeutics, Inc. | February 13, 2023 | 974,639 | 7.1% |
| InflaRx N.V.Sold out | February 14, 2022 | 0 | 0.0% |
| ABEONA THERAPEUTICS INC.Sold out | February 16, 2021 | 0 | 0.0% |
| CONSTELLATION PHARMACEUTICALS INC | February 16, 2021 | 1,024,800 | 2.2% |
| GERON CORP | February 16, 2021 | 12,754,228 | 4.0% |
| Millendo Therapeutics, Inc. | February 16, 2021 | 270,000 | 1.4% |
| NextCure, Inc.Sold out | February 16, 2021 | 0 | 0.0% |
| PROTHENA CORP PUBLIC LTD CO | February 16, 2021 | 977,647 | 2.4% |
View GREAT POINT PARTNERS LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-04-08 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View GREAT POINT PARTNERS LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.