Perceptive Advisors Q4 2020 13F Holdings

Perceptive Advisors Q4 2020 holdings
TickerName Value Shares↓ Weighting
MRTX MIRATI THERAPEUTICS INCAdd  $811,244
42.2%
3,693,516
7.5%
8.71%
4.5%
FOLD AMICUS THERAPEUTICS INCReduce  $579,837
63.5%
25,112,048
-0.0%
6.22%
20.2%
BBIO BRIDGEBIO PHARMA INC  $476,883
89.5%
6,706,2680.0%5.12%
39.3%
RETROPHIN INCnote 2.500% 9/1  $442,521
13.4%
45,000,0000.0%4.75%
-16.6%
IOVA IOVANCE BIOTHERAPEUTIC...Reduce  $425,316
28.1%
9,166,304
-9.1%
4.56%
-5.8%
NVTA INVITAE CORPNew  $304,5637,284,4663.27%
SWTX SPRINGWORKS THERAPEUTI...Add  $302,968
82.6%
4,177,721
20.0%
3.25%
34.2%
GBT GLOBAL BLOOD THERAPEUT...Reduce  $245,771
-23.2%
5,674,711
-2.2%
2.64%
-43.5%
HZNP HORIZON THERAPEUTICS P...New  $225,5973,084,0422.42%
ZYME ZYMEWORKS INCReduce  $203,265
-0.8%
4,300,999
-2.3%
2.18%
-27.1%
RCKT ROCKET PHARMACEUTICALS...Add  $186,284
272.3%
3,396,867
55.2%
2.00%
173.5%
NBIX NEUROCRINE BIOSCIENCES...Add  $182,040
22.2%
1,899,215
22.6%
1.95%
-10.1%
COLLEGIUM PHARMACEUTIC...note 2.625% 2/1  $173,250
5.8%
17,500,0000.0%1.86%
-22.3%
NVRO NEVRO CORPAdd  $169,217
47.0%
977,565
18.3%
1.82%
8.1%
NEVRO CORPnote 2.750% 4/0  $165,420
16.6%
9,000,0000.0%1.78%
-14.3%
OM OUTSET MED INC  $161,870
13.7%
2,847,8220.0%1.74%
-16.5%
VBIV VBI VACCINES INC  $151,366
-3.8%
55,042,4650.0%1.62%
-29.3%
ATNX ATHENEX INC  $149,669
-7.2%
13,532,4670.0%1.61%
-31.8%
AVIR ATEA PHARMACEUTICALS INCNew  $129,9033,109,2241.39%
NVAX NOVAVAX INCAdd  $116,305
51.7%
1,043,000
47.4%
1.25%
11.4%
FREQ FREQUENCY THERAPEUTICS...Add  $114,935
83.7%
3,259,635
0.1%
1.23%
35.0%
KOD KODIAK SCIENCES INCReduce  $110,408
78.8%
751,533
-27.9%
1.18%
31.4%
ATHA ATHIRA PHARMA INC  $106,682
85.5%
3,114,8050.0%1.14%
36.5%
MGTX MEIRAGTX HLDGS PLCAdd  $104,970
23.2%
6,933,277
7.8%
1.13%
-9.5%
CCCC C4 THERAPEUTICS INCNew  $104,6433,158,5661.12%
RLAY RELAY THERAPEUTICS INC  $96,810
-2.4%
2,329,4070.0%1.04%
-28.2%
TVTX TRAVERE THERAPEUTICS INCNew  $95,2183,493,6071.02%
EIDX EIDOS THERAPEUTICS INC  $90,385
160.4%
686,9220.0%0.97%
91.3%
ALBO ALBIREO PHARMA INC  $88,529
12.4%
2,360,1390.0%0.95%
-17.4%
QTNT QUOTIENT LTD  $84,406
1.4%
16,200,8180.0%0.91%
-25.5%
KRON KRONOS BIO INCNew  $83,0412,780,0970.89%
ARWR ARROWHEAD PHARMACEUTIC...New  $82,1641,070,8140.88%
SLDB SOLID BIOSCIENCES INCAdd  $81,893
497.7%
10,803,857
60.1%
0.88%
339.5%
CHRS COHERUS BIOSCIENCES INCAdd  $81,197
21.7%
4,671,836
28.5%
0.87%
-10.6%
CERE CEREVEL THERAPEUTICS H...New  $75,3404,544,0620.81%
PRVB PROVENTION BIO INCReduce  $71,561
30.8%
4,224,389
-1.0%
0.77%
-3.9%
KDMN KADMON HLDGS INC  $65,202
5.9%
15,711,3340.0%0.70%
-22.1%
IMVT IMMUNOVANT INC  $64,666
31.3%
1,400,0000.0%0.69%
-3.5%
ONCR ONCORUS INCNew  $64,3361,989,9870.69%
NARI INARI MED INCReduce  $58,353
-0.4%
668,500
-21.2%
0.63%
-26.8%
PMVP PMV PHARMACEUTICALS INCAdd  $54,471
153.4%
885,556
46.2%
0.58%
86.3%
ZNTL ZENTALIS PHARMACEUTICA...  $54,537
58.9%
1,050,0030.0%0.58%
16.8%
TARS TARSUS PHARMACEUTICALS...New  $53,5801,296,4160.58%
ADPT ADAPTIVE BIOTECHNOLOGI...Add  $53,504
32.6%
904,854
9.0%
0.57%
-2.5%
CRNX CRINETICS PHARMACEUTIC...  $51,634
-10.0%
3,659,3810.0%0.55%
-33.8%
UROV UROVANT SCIENCES LTDAdd  $50,274
127.4%
3,116,831
31.7%
0.54%
67.2%
CMPS COMPASS PATHWAYS PLCsponsored ads  $49,898
36.5%
1,047,4040.0%0.54%
0.2%
AGRX AGILE THERAPEUTICS INC  $45,690
-5.6%
15,919,9250.0%0.49%
-30.7%
ARNA ARENA PHARMACEUTICALS INCReduce  $44,178
-5.5%
575,007
-8.0%
0.47%
-30.6%
FMTX FORMA THERAPEUTICS HLD...  $43,625
-30.0%
1,250,0000.0%0.47%
-48.6%
ALDX ALDEYRA THERAPEUTICS INC  $43,118
-7.4%
6,285,4580.0%0.46%
-31.9%
STOK STOKE THERAPEUTICS INC  $41,616
84.9%
671,9780.0%0.45%
35.9%
COLL COLLEGIUM PHARMACEUTIC...  $41,223
-3.8%
2,058,0680.0%0.44%
-29.4%
VRCA VERRICA PHARMACEUTICAL...  $39,254
48.7%
3,410,4120.0%0.42%
9.4%
SAGE SAGE THERAPEUTICS INCNew  $38,064440,0000.41%
LYRA LYRA THERAPEUTICS INC  $36,737
2.0%
3,222,5610.0%0.39%
-25.1%
VYNE VYNE THERAPEUTICS INC  $36,145
-4.8%
22,876,4100.0%0.39%
-30.0%
COGT COGENT BIOSCIENCES INCNew  $35,8103,188,7500.38%
NEPT NEPTUNE WELLNESS SOLUT...Add  $34,655
-15.5%
22,214,683
14.3%
0.37%
-37.9%
ADMA ADMA BIOLOGICS INC  $32,340
-18.4%
16,584,8020.0%0.35%
-40.1%
RNA AVIDITY BIOSCIENCES INC  $31,538
-9.3%
1,235,8180.0%0.34%
-33.5%
RAPT RAPT THERAPEUTICS INCNew  $31,1551,577,4810.33%
ISEE IVERIC BIO INCAdd  $30,976
57.8%
4,482,713
28.8%
0.33%
15.7%
SILK SILK RD MED INCReduce  $29,292
-16.2%
465,100
-10.6%
0.31%
-38.4%
ALLO ALLOGENE THERAPEUTICS INC  $28,869
-33.1%
1,143,7900.0%0.31%
-50.8%
MGNX MACROGENICS INCReduce  $28,828
-11.4%
1,261,060
-2.3%
0.31%
-34.9%
VERU VERU INCAdd  $28,113
550.3%
3,250,000
97.0%
0.30%
379.4%
XBI SPDR SER TR XBIputs&p biotech  $28,156
26.3%
200,0000.0%0.30%
-7.1%
ACCD ACCOLADE INCAdd  $27,256
139.2%
626,591
113.8%
0.29%
76.5%
CNCE CONCERT PHARMACEUTICAL...  $27,184
28.7%
2,150,6410.0%0.29%
-5.2%
IMTX IMMATICS N.V  $26,975
1.7%
2,500,0000.0%0.29%
-25.3%
REGN REGENERON PHARMACEUTICALSAdd  $26,656
852.3%
55,175
1003.5%
0.29%
597.6%
LUNG PULMONX CORPNew  $26,573385,0000.28%
FUSN FUSION PHARMACEUTICALS...  $26,273
-2.2%
2,235,9830.0%0.28%
-28.1%
ESTA ESTABLISHMENT LABS HLD...Add  $26,221
108.5%
696,633
2.7%
0.28%
52.7%
ANAB ANAPTYSBIO INCNew  $25,7001,195,3360.28%
FDMT 4D MOLECULAR THERAPEUT...New  $24,881600,2560.27%
ONEM 1LIFE HEALTHCARE INCAdd  $22,691
185.9%
519,844
85.8%
0.24%
110.3%
PCVX VAXCYTE INC  $22,585
-46.2%
850,0000.0%0.24%
-60.5%
NSTG NANOSTRING TECHNOLOGIE...New  $22,592337,8000.24%
GERN GERON CORP  $21,404
-8.6%
13,461,5380.0%0.23%
-32.7%
RACA THERAPEUTICS ACQUISITI...  $20,880
-3.2%
1,500,0000.0%0.22%
-28.9%
AMRS AMYRIS INC  $20,583
140.2%
3,333,3320.0%0.22%
76.8%
VRNA VERONA PHARMA PLCsponsored ads  $20,222
12.2%
2,888,8890.0%0.22%
-17.5%
WVE WAVE LIFE SCIENCES LTD  $19,675
-7.3%
2,500,0000.0%0.21%
-31.9%
LPTX LEAP THERAPEUTICS INC  $19,072
13.6%
8,476,4960.0%0.20%
-16.3%
VTRS VIATRIS INCNew  $18,8231,004,4190.20%
RGEN REPLIGEN CORPNew  $18,68497,5000.20%
SCYX SCYNEXIS INCNew  $18,3602,400,0000.20%
HRMY HARMONY BIOSCIENCES HL...Add  $18,170
23.1%
502,622
15.4%
0.20%
-9.3%
NBTX NANOBIOTIX SAsponsored adsNew  $18,1501,100,0000.20%
DRNA DICERNA PHARMACEUTICAL...  $17,624
22.5%
800,0000.0%0.19%
-10.0%
DBVT DBV TECHNOLOGIES S Asponsored adrReduce  $17,280
46.7%
6,595,505
-3.1%
0.18%
7.6%
CTMX CYTOMX THERAPEUTICS INC  $16,880
-1.5%
2,577,0430.0%0.18%
-27.6%
MORF MORPHIC HLDG INC  $16,339
22.7%
487,0000.0%0.18%
-9.8%
LGVWU LONGVIEW ACQUISITION CORPunit 99/99/9999  $15,155
113.3%
700,0000.0%0.16%
56.7%
TARA PROTARA THERAPEUTICS INC  $14,733
43.8%
608,5440.0%0.16%
5.3%
PPH VANECK VECTO... PPHputpharmaceutical  $13,294
6.9%
200,0000.0%0.14%
-21.4%
AMWL AMERICAN WELL CORPcl aAdd  $13,298
-1.4%
525,000
15.4%
0.14%
-27.4%
FBRX FORTE BIOSCIENCES INCNew  $12,744350,0000.14%
TSHA TAYSHA GENE THERAPIES INC  $12,485
18.5%
470,4400.0%0.13%
-13.0%
TCRR TCR2 THERAPEUTICS INC  $12,372
52.2%
400,0000.0%0.13%
11.8%
HCAT HEALTH CATALYST INCReduce  $12,018
12.8%
276,084
-5.2%
0.13%
-17.3%
BLSA BCLS ACQUISITION CORPNew  $11,1401,000,0000.12%
SCPEU SC HEALTH CORPunit 99/99/9999  $10,990
3.7%
1,000,0000.0%0.12%
-23.9%
CRIS CURIS INCNew  $10,2381,250,0000.11%
MRVI MARAVAI LIFESCIENCES H...New  $9,818350,0000.10%
VRAY VIEWRAY INC  $9,366
9.1%
2,451,7480.0%0.10%
-19.2%
RVMD REVOLUTION MEDICINES INC  $8,877
13.8%
224,2240.0%0.10%
-16.7%
PSTX POSEIDA THERAPEUTICS INC  $8,642
23.7%
787,7450.0%0.09%
-8.8%
DYN DYNE THERAPEUTICS INC  $8,400
4.0%
400,0000.0%0.09%
-23.7%
SHC SOTERA HEALTH CONew  $8,232300,0000.09%
AQST AQUESTIVE THERAPEUTICS...Reduce  $7,414
-12.7%
1,385,720
-20.8%
0.08%
-35.5%
SNDX SYNDAX PHARMACEUTICALS...New  $6,672300,0000.07%
VINC VINCERA PHARMA INCNew  $6,273300,0000.07%
SGTX SIGILON THERAPEUTICS INCNew  $6,004125,0000.06%
HSAQ HEALTH SCIENCES ACQ CO...  $5,765
16.5%
450,0000.0%0.06%
-13.9%
BCTG BCTG ACQUISITION CORP  $5,720
10.4%
500,0000.0%0.06%
-19.7%
PHR PHREESIA INCNew  $5,426100,0000.06%
CHFWU CONSONANCE HFW ACQUISI...unit 99/99/9999New  $5,235500,0000.06%
DFHTU DEERFIELD HEALTHCARE T...unit 07/16/2025  $4,500
41.1%
300,0000.0%0.05%
2.1%
MASS 908 DEVICES INCNew  $4,41477,5000.05%
AVXL ANAVEX LIFE SCIENCES CORPNew  $4,212780,0070.04%
PTGX PROTAGONIST THERAPEUTI...New  $4,104203,5910.04%
MOTS MOTUS GI HLDGS INC  $3,906
-3.0%
4,210,5420.0%0.04%
-28.8%
MTEM MOLECULAR TEMPLATES INCReduce  $3,867
-85.7%
411,818
-83.4%
0.04%
-89.6%
BNR BURNING ROCK BIOTECH LTDsponsored ads  $3,465
-7.9%
150,0000.0%0.04%
-32.7%
GRTX GALERA THERAPEUTICS INC  $3,325
13.2%
325,0000.0%0.04%
-16.3%
LSAQ LIFESCI ACQUISITION II...New  $3,201300,0000.03%
ADAP ADAPTIMMUNE THERAPEUTI...sponds adr  $2,156
-32.5%
400,0000.0%0.02%
-51.1%
EIGR EIGER BIOPHARMACEUTICA...  $1,719
51.1%
139,8900.0%0.02%
5.9%
RACE FERRARI N V  $1,423
24.7%
6,2000.0%0.02%
-11.8%
VINCW VINCERA PHARMA INC*w exp 12/24/202New  $990300,0000.01%
SRRA SIERRA ONCOLOGY INC  $1,068
50.2%
66,6550.0%0.01%
10.0%
ABCL ABCELLERA BIOLOGICS INCNew  $80520,0000.01%
LEGN LEGEND BIOTECH CORPsponsored ads  $704
-8.8%
25,0000.0%0.01%
-27.3%
IPOF SOCIAL CAPITAL HEDOSOP...New  $67140,0000.01%
DFHT DEERFIELD HEALTHCARE T...New  $31220,0000.00%
OTLKW OUTLOOK THERAPEUTICS INC*w exp 02/18/202  $93
72.2%
420,8750.0%0.00%0.0%
BIO BIO RAD LABS INCcl aSold out  $0-489-0.00%
REPL REPLIMUNE GROUP INCSold out  $0-19,230-0.01%
CVET COVETRUS INCSold out  $0-26,075-0.01%
PSNL PERSONALIS INCSold out  $0-27,272-0.01%
AKRO AKERO THERAPEUTICS INCSold out  $0-21,938-0.01%
CLDX CELLDEX THERAPEUTICS I...Sold out  $0-49,751-0.01%
TGTX TG THERAPEUTICS INCSold out  $0-33,893-0.01%
LVGO LIVONGO HEALTH INCSold out  $0-10,663-0.02%
TRILLIUM THERAPEUTICS INCSold out  $0-114,674-0.02%
ATEC ALPHATEC HLDGS INCSold out  $0-561,574-0.05%
LSACU LIFESCI ACQUISITION CORPunit 03/31/2025Sold out  $0-300,000-0.06%
TBIO TRANSLATE BIO INCSold out  $0-315,237-0.06%
TWST TWIST BIOSCIENCE CORPSold out  $0-112,756-0.12%
ATRC ATRICURE INCSold out  $0-216,449-0.13%
PODD INSULET CORPSold out  $0-37,733-0.13%
HOLX HOLOGIC INCSold out  $0-170,000-0.16%
MYL MYLAN N.VSold out  $0-1,004,419-0.22%
UMRX UNUM THERAPEUTICS INCSold out  $0-7,955,000-0.27%
BIIB BIOGEN INC BIIBcallSold out  $0-100,000-0.41%
TPTX TURNING POINT THERAPEU...Sold out  $0-329,890-0.42%
RTRX RETROPHIN INCSold out  $0-3,240,112-0.87%
BPMC BLUEPRINT MEDICINES CORPSold out  $0-664,574-0.90%
IMMU IMMUNOMEDICS INCSold out  $0-912,140-1.13%
CRSP CRISPR THERAPEUTICS AGnamen aktSold out  $0-1,341,308-1.64%
MYOK MYOKARDIA INCSold out  $0-1,395,017-2.78%
CYTOKINETICS INCnote 4.000%11/1Sold out  $0-9,770,000-3.19%