$4.15 Billion is the total value of Perceptive Advisors's 110 reported holdings in Q2 2024. The portfolio turnover from Q1 2024 to Q2 2024 was 41.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CERE | CEREVEL THERAPEUTICS HLDNG I | $441,402,480 | -3.3% | 10,794,876 | 0.0% | 10.63% | +33.2% | |
| FOLD | AMICUS THERAPEUTICS INC | $278,329,964 | -15.8% | 28,057,456 | 0.0% | 6.70% | +15.9% | |
| Sell | ARCELLX INC | $214,674,695 | -21.5% | 3,889,739 | -1.1% | 5.17% | +8.0% | |
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS INC | $207,983,798 | -27.2% | 25,933,142 | +34.6% | 5.01% | +0.3% |
| Sell | NUVALENT INC | $193,372,981 | -7.5% | 2,549,077 | -8.4% | 4.66% | +27.4% | |
| RYTM | Buy | RHYTHM PHARMACEUTICALS INC | $141,516,534 | -0.1% | 3,446,579 | +5.4% | 3.41% | +37.6% |
| PCVX | Sell | VAXCYTE INC | $140,645,530 | +6.5% | 1,862,608 | -3.6% | 3.39% | +46.7% |
| Buy | SOLENO THERAPEUTICS INC | $130,763,021 | -0.6% | 3,204,976 | +4.2% | 3.15% | +36.8% | |
| ITCI | Buy | INTRA-CELLULAR THERAPIES INC | $117,556,715 | +61.0% | 1,716,407 | +62.6% | 2.83% | +121.5% |
| IMTX | Buy | IMMATICS N.V | $93,961,168 | +95.1% | 8,086,159 | +76.5% | 2.26% | +168.4% |
| NBIX | Sell | NEUROCRINE BIOSCIENCES INC | $89,472,972 | -19.4% | 649,909 | -19.2% | 2.16% | +11.0% |
| Buy | APOGEE THERAPEUTICS INC | $82,856,776 | -39.5% | 2,105,636 | +2.2% | 2.00% | -16.7% | |
| MDGL | Sell | MADRIGAL PHARMACEUTICALS INC | $74,130,336 | -35.4% | 264,600 | -38.5% | 1.79% | -11.1% |
| CRY | Buy | ARTIVION INC | $71,658,482 | +26.9% | 2,793,703 | +4.7% | 1.73% | +74.7% |
| Buy | SPYRE THERAPEUTICS INC | $71,259,233 | -26.5% | 3,031,018 | +18.6% | 1.72% | +1.1% | |
| CRNX | CRINETICS PHARMACEUTICALS IN | $66,119,132 | -4.3% | 1,476,203 | 0.0% | 1.59% | +31.8% | |
| EOLS | EVOLUS INC | $62,428,708 | -22.5% | 5,753,798 | 0.0% | 1.50% | +6.7% | |
| SWTX | Sell | SPRINGWORKS THERAPEUTICS INC | $62,267,079 | -44.1% | 1,652,962 | -26.9% | 1.50% | -23.0% |
| Buy | CARGO THERAPEUTICS INC | $60,474,925 | -21.4% | 3,683,004 | +6.8% | 1.46% | +8.2% | |
| ASTRIA THERAPEUTICS INC | $59,017,322 | -35.3% | 6,485,420 | 0.0% | 1.42% | -11.0% | ||
| NTRA | Sell | NATERA INC | $57,393,700 | -17.1% | 530,000 | -30.0% | 1.38% | +14.0% |
| VRCA | VERRICA PHARMACEUTICALS INC | $51,753,037 | +23.1% | 7,099,182 | 0.0% | 1.25% | +69.7% | |
| Sell | BIOHAVEN LTD | $51,552,403 | -45.4% | 1,485,232 | -13.9% | 1.24% | -24.8% | |
| IMVT | Sell | IMMUNOVANT INC | $50,787,950 | -47.0% | 1,923,786 | -35.1% | 1.22% | -27.0% |
| MGTX | MEIRAGTX HLDGS PLC | $47,667,625 | -30.6% | 11,331,103 | 0.0% | 1.15% | -4.5% | |
| PTGX | Buy | PROTAGONIST THERAPEUTICS INC | $43,961,668 | +52.8% | 1,268,735 | +27.6% | 1.06% | +110.5% |
| SOLID BIOSCIENCES INC | $39,160,682 | -57.4% | 6,906,646 | 0.0% | 0.94% | -41.4% | ||
| CELC | CELCUITY INC | $38,694,130 | -24.2% | 2,362,279 | 0.0% | 0.93% | +4.4% | |
| MDT | Sell | MEDTRONIC PLC | $38,620,242 | -69.0% | 490,665 | -65.7% | 0.93% | -57.3% |
| VKTX | Sell | VIKING THERAPEUTICS INC | $38,240,195 | -53.1% | 721,377 | -27.4% | 0.92% | -35.4% |
| APLT | APPLIED THERAPEUTICS INC | $37,383,350 | -31.3% | 8,005,000 | 0.0% | 0.90% | -5.5% | |
| AXSM | Sell | AXSOME THERAPEUTICS INC | $36,958,436 | -58.1% | 459,111 | -58.5% | 0.89% | -42.3% |
| CNTA | Buy | CENTESSA PHARMACEUTICALS PLCsponsored ads | $35,517,762 | +1.9% | 3,933,307 | +27.6% | 0.86% | +40.2% |
| TARS | TARSUS PHARMACEUTICALS INC | $35,236,587 | -25.2% | 1,296,416 | 0.0% | 0.85% | +2.9% | |
| AKRO | Buy | AKERO THERAPEUTICS INC | $35,187,584 | +0.4% | 1,499,897 | +8.1% | 0.85% | +38.3% |
| VRNA | Sell | VERONA PHARMA PLCsponsored ads | $35,191,664 | -41.9% | 2,433,725 | -35.3% | 0.85% | -19.9% |
| EWTX | Sell | EDGEWISE THERAPEUTICS INC | $33,434,070 | -21.0% | 1,856,417 | -20.0% | 0.80% | +8.8% |
| Buy | ACRIVON THERAPEUTICS INC | $31,092,976 | +44.6% | 5,360,858 | +78.2% | 0.75% | +99.2% | |
| Sell | PRAXIS PRECISION MEDICINES I | $31,029,513 | -38.1% | 750,230 | -8.7% | 0.75% | -14.8% | |
| ADMA | Sell | ADMA BIOLOGICS INC | $30,979,780 | -27.0% | 2,771,000 | -56.9% | 0.75% | +0.4% |
| BBIO | Sell | BRIDGEBIO PHARMA INC | $30,784,714 | -29.5% | 1,215,346 | -13.9% | 0.74% | -3.0% |
| ALDX | Buy | ALDEYRA THERAPEUTICS INC | $30,703,067 | +9.3% | 9,275,851 | +7.9% | 0.74% | +50.4% |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | $29,470,453 | -20.4% | 12,594,211 | 0.0% | 0.71% | +9.6% | |
| New | CONTINEUM THERAPEUTICS INCcl a | $27,589,023 | – | 1,566,668 | +100.0% | 0.66% | – | |
| ISRG | Sell | INTUITIVE SURGICAL INC | $27,491,730 | -32.3% | 61,800 | -39.3% | 0.66% | -6.9% |
| ARVN | Sell | ARVINAS INC | $27,358,678 | -46.4% | 1,027,749 | -16.9% | 0.66% | -26.2% |
| RCKT | Sell | ROCKET PHARMACEUTICALS INC | $26,839,233 | -44.7% | 1,246,597 | -30.8% | 0.65% | -23.9% |
| Sell | DISC MEDICINE INC | $24,943,406 | -57.4% | 553,437 | -41.1% | 0.60% | -41.3% | |
| LIVN | Buy | LIVANOVA PLC | $24,340,080 | +45.5% | 444,000 | +48.5% | 0.59% | +100.0% |
| Sell | CG ONCOLOGY INC | $23,162,751 | -59.5% | 733,695 | -43.7% | 0.56% | -44.3% | |
| XENE | Sell | XENON PHARMACEUTICALS INC | $22,741,151 | -40.8% | 583,256 | -34.6% | 0.55% | -18.5% |
| OCUL | OCULAR THERAPEUTIX INC | $22,739,361 | -24.8% | 3,324,468 | 0.0% | 0.55% | +3.6% | |
| PEPGEN INC | $22,510,590 | +8.6% | 1,410,438 | 0.0% | 0.54% | +49.3% | ||
| VRDN | Sell | VIRIDIAN THERAPEUTICS INC | $21,230,082 | -66.8% | 1,631,828 | -55.4% | 0.51% | -54.4% |
| ORCHESTRA BIOMED HLDGS INC | $20,748,930 | +54.6% | 2,545,881 | 0.0% | 0.50% | +112.8% | ||
| MRUS | New | MERUS N V | $17,751,000 | – | 300,000 | +100.0% | 0.43% | – |
| New | RAPPORT THERAPEUTICS INC | $17,402,737 | – | 748,183 | +100.0% | 0.42% | – | |
| Buy | TYRA BIOSCIENCES INC | $16,107,798 | +46.8% | 1,007,367 | +50.5% | 0.39% | +102.1% | |
| New | INHIBRX BIOSCIENCES INC | $15,077,248 | – | 1,064,026 | +100.0% | 0.36% | – | |
| ARQT | Buy | ARCUTIS BIOTHERAPEUTICS INC | $14,494,050 | +95.0% | 1,558,500 | +107.8% | 0.35% | +168.5% |
| ATHA | ATHIRA PHARMA INC | $14,317,855 | -3.3% | 5,402,964 | 0.0% | 0.34% | +33.2% | |
| Buy | ZYMEWORKS INC | $14,192,221 | +25.5% | 1,667,711 | +55.2% | 0.34% | +72.7% | |
| CGEM | New | CULLINAN THERAPEUTICS INC | $13,078,535 | – | 749,916 | +100.0% | 0.32% | – |
| PROCEPT BIOROBOTICS CORP | $12,869,158 | +23.6% | 210,659 | 0.0% | 0.31% | +70.3% | ||
| INSM | New | INSMED INC | $12,060,000 | – | 180,000 | +100.0% | 0.29% | – |
| BCYC | New | BICYCLE THERAPEUTICS PLCsponsored ads | $11,577,280 | – | 572,000 | +100.0% | 0.28% | – |
| ICLR | New | ICON PLC | $9,795,938 | – | 31,250 | +100.0% | 0.24% | – |
| New | TEMPUS AI INCcl a | $9,625,000 | – | 275,000 | +100.0% | 0.23% | – | |
| ARRIVENT BIOPHARMA INC | $7,698,250 | +3.9% | 415,000 | 0.0% | 0.18% | +42.3% | ||
| Sell | ENGENE HOLDINGS INC | $7,544,000 | -55.4% | 800,000 | -19.9% | 0.18% | -38.5% | |
| SBTX | ARS PHARMACEUTICALS INC | $7,380,885 | -16.7% | 867,319 | 0.0% | 0.18% | +14.8% | |
| ARGX | New | ARGENX SEsponsored adr | $6,708,624 | – | 15,600 | +100.0% | 0.16% | – |
| ALLO | New | ALLOGENE THERAPEUTICS INC | $6,349,250 | – | 2,725,000 | +100.0% | 0.15% | – |
| VERU | Buy | VERU INC | $5,942,335 | +52.0% | 7,063,277 | +26.5% | 0.14% | +110.3% |
| KALV | KALVISTA PHARMACEUTICALS INC | $5,890,000 | -0.7% | 500,000 | 0.0% | 0.14% | +36.5% | |
| RXRX | New | RECURSION PHARMACEUTICALS INcl a | $5,769,225 | – | 769,230 | +100.0% | 0.14% | – |
| EYPT | Buy | EYEPOINT PHARMACEUTICALS INC | $5,570,384 | -54.3% | 640,274 | +8.6% | 0.13% | -37.1% |
| IMVT | Buy | IMMUNOVANT INCcall | $5,280,000 | +63.4% | 200,000 | +100.0% | 0.13% | +122.8% |
| HELIX ACQUISITION CORP II | $5,110,000 | -1.7% | 500,000 | 0.0% | 0.12% | +35.2% | ||
| MREO | New | MEREO BIOPHARMA GROUP PLCspon ads | $4,511,700 | – | 1,253,250 | +100.0% | 0.11% | – |
| CABA | Sell | CABALETTA BIO INC | $4,376,137 | -85.1% | 585,045 | -65.9% | 0.10% | -79.5% |
| Sell | PRECISION BIOSCIENCES INC | $4,147,831 | -36.3% | 426,293 | -11.3% | 0.10% | -12.3% | |
| New | SKYE BIOSCIENCE INC | $4,005,000 | – | 500,000 | +100.0% | 0.10% | – | |
| TRINITY BIOTECH PLCspons ard new | $3,834,000 | +4.4% | 1,800,000 | 0.0% | 0.09% | +43.8% | ||
| IRTC | Sell | IRHYTHM TECHNOLOGIES INC | $3,789,466 | -86.7% | 35,205 | -85.6% | 0.09% | -81.7% |
| LYRA | LYRA THERAPEUTICS INC | $3,533,844 | -95.5% | 12,757,562 | 0.0% | 0.08% | -93.9% | |
| BDSX | New | BIODESIX INC | $3,326,036 | – | 2,173,880 | +100.0% | 0.08% | – |
| ENVVENO MEDICAL CORPORATION | $3,272,404 | -3.5% | 623,315 | 0.0% | 0.08% | +33.9% | ||
| FHTX | New | FOGHORN THERAPEUTICS INC | $3,128,000 | – | 544,000 | +100.0% | 0.08% | – |
| NBTX | NANOBIOTIXsponsored ads | $2,775,330 | -23.1% | 555,066 | 0.0% | 0.07% | +6.3% | |
| SAVA | New | CASSAVA SCIENCES INCput | $2,260,050 | – | 183,000 | +100.0% | 0.05% | – |
| ABSCI CORPORATION | $2,156,000 | -45.8% | 700,000 | 0.0% | 0.05% | -25.7% | ||
| XBI | New | SPDR SER TRs&p biotech | $2,101,272 | – | 22,665 | +100.0% | 0.05% | – |
| XFOR | X4 PHARMACEUTICALS INC | $2,056,363 | -58.3% | 3,545,454 | 0.0% | 0.05% | -41.9% | |
| FBRX | FORTE BIOSCIENCES INC | $1,753,498 | -22.9% | 3,265,359 | 0.0% | 0.04% | +5.0% | |
| RVNC | REVANCE THERAPEUTICS INC | $1,542,000 | -47.8% | 600,000 | 0.0% | 0.04% | -28.8% | |
| New | STRUCTURE THERAPEUTICS INCsponsored ads | $1,368,638 | – | 34,852 | +100.0% | 0.03% | – | |
| NVAX | Sell | NOVAVAX INCput | $1,266,000 | -62.2% | 100,000 | -85.7% | 0.03% | -49.2% |
| KYVERNA THERAPEUTICS INC | $1,125,000 | -69.8% | 150,000 | 0.0% | 0.03% | -58.5% | ||
| FATE | New | FATE THERAPEUTICS INC | $1,133,486 | – | 345,575 | +100.0% | 0.03% | – |
| EGRX | New | EAGLE PHARMACEUTICALS INC | $970,844 | – | 173,365 | +100.0% | 0.02% | – |
| VBI VACCINES INC CDA | $832,728 | +10.0% | 1,261,710 | 0.0% | 0.02% | +53.8% | ||
| TCMD | Sell | TACTILE SYS TECHNOLOGY INC | $747,910 | -94.9% | 62,639 | -93.1% | 0.02% | -93.0% |
| SYROS PHARMACEUTICALS INC | $602,451 | -3.6% | 116,754 | 0.0% | 0.02% | +36.4% | ||
| New | SINGULAR GENOMICS SYSTEMS IN | $599,071 | – | 70,896 | +100.0% | 0.01% | – | |
| CAREMAX INCcl a new | $342,174 | -42.1% | 122,643 | 0.0% | 0.01% | -20.0% | ||
| AXGN | Sell | AXOGEN INC | $220,248 | -98.2% | 30,421 | -98.0% | 0.01% | -97.7% |
| REVOLUTION MEDICINES INC*w exp 12/17/202 | $25,525 | -44.1% | 250,000 | 0.0% | 0.00% | 0.0% | ||
| CMAXW | CAREMAX INC*w exp 06/08/202 | $846 | -17.5% | 60,000 | 0.0% | 0.00% | – | |
| SURROZEN INC*w exp 08/01/203 | $2,767 | -45.0% | 166,666 | 0.0% | 0.00% | – | ||
| Exit | AMYLYX PHARMACEUTICALS INC | $0 | – | -300,000 | -100.0% | -0.02% | – | |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -48,200 | -100.0% | -0.02% | – |
| OMIC | Exit | SINGULAR GENOMICS SYSTEMS IN | $0 | – | -2,126,893 | -100.0% | -0.02% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INCcall | $0 | – | -100,000 | -100.0% | -0.05% | – |
| APLT | Exit | APPLIED THERAPEUTICS INCcall | $0 | – | -500,000 | -100.0% | -0.06% | – |
| Exit | NEWAMSTERDAM PHARMA COMPANYordinary shares | $0 | – | -175,000 | -100.0% | -0.07% | – | |
| ESTA | Exit | ESTABLISHMENT LABS HLDGS INC | $0 | – | -82,299 | -100.0% | -0.07% | – |
| Exit | AMYLYX PHARMACEUTICALS INCcall | $0 | – | -1,679,125 | -100.0% | -0.08% | – | |
| XBI | Exit | SPDR SER TRput | $0 | – | -50,000 | -100.0% | -0.08% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -378,327 | -100.0% | -0.10% | – |
| IBRX | Exit | IMMUNITYBIO INC | $0 | – | -1,052,887 | -100.0% | -0.10% | – |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -883,333 | -100.0% | -0.10% | – |
| MORF | Exit | MORPHIC HLDG INC | $0 | – | -288,221 | -100.0% | -0.18% | – |
| RAPT | Exit | RAPT THERAPEUTICS INC | $0 | – | -1,223,472 | -100.0% | -0.19% | – |
| Exit | MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $0 | – | -339,012 | -100.0% | -0.30% | – | |
| Exit | DISC MEDICINE INCput | $0 | – | -300,000 | -100.0% | -0.33% | – | |
| ABBV | Exit | ABBVIE INC | $0 | – | -106,500 | -100.0% | -0.34% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -618,885 | -100.0% | -0.35% | – |
| AUTL | Exit | AUTOLUS THERAPEUTICS PLCspon ads | $0 | – | -4,330,745 | -100.0% | -0.48% | – |
| TMCI | Exit | TREACE MED CONCEPTS INC | $0 | – | -2,304,954 | -100.0% | -0.53% | – |
| Exit | LANDOS BIOPHARMA INC | $0 | – | -1,486,991 | -100.0% | -0.56% | – | |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -525,683 | -100.0% | -1.19% | – |
| FUSN | Exit | FUSION PHARMACEUTICALS INC | $0 | – | -6,825,395 | -100.0% | -2.55% | – |
| INBX | Exit | INHIBRX INC | $0 | – | -4,256,104 | -100.0% | -2.60% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR/A filed 2024-08-16
About Perceptive Advisors
Perceptive Advisors is a New York-based hedge fund that specializes in healthcare investments. The company was founded in 1999 by Joseph Edelman, who serves as the CEO and Chief Investment Officer. Since its inception, Perceptive Advisors has become one of the most successful healthcare-focused hedge funds in the world, with over $5 billion in assets under management.
The company's investment strategy is based on a deep understanding of the healthcare industry and a focus on identifying promising companies with innovative products and technologies. Perceptive Advisors invests in a wide range of healthcare sectors, including biotechnology, pharmaceuticals, medical devices, and healthcare services.
One of the key factors behind Perceptive Advisors' success is its team of experienced professionals. In addition to Joseph Edelman, the company's leadership team includes Adam Stone, the COO, and Jeremy Goldberg, the Chief Scientific Officer. The team also includes a group of highly skilled analysts and researchers who are experts in their respective fields.
Perceptive Advisors has a strong track record of generating high returns for its investors. However, it is important to note that investing in hedge funds carries significant risks, and investors should carefully consider their investment objectives and risk tolerance before investing. As with any investment, it is important to conduct thorough research and seek the advice of a qualified financial advisor before making any investment decisions.
It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| NEUROCRINE BIOSCIENCES SHARES | 45 | Q2 2024 | 15.7% |
| AMICUS THERAPEUTICS SHARES | 42 | Q2 2024 | 14.0% |
| ALDEYRA THERAPEUTICS SHARES | 38 | Q2 2024 | 3.3% |
| QUOTIENT TECHNOLOGY INC | 34 | Q3 2022 | 2.7% |
| ADMA BIOLOGICS SHARES | 32 | Q2 2024 | 1.4% |
| GLOBAL BLOOD THERAPEUTICS SHARES | 29 | Q3 2022 | 9.3% |
| IOVANCE BIOTHERAPEUTICS INC | 29 | Q2 2024 | 9.1% |
| RETROPHIN SHARES | 28 | Q3 2020 | 5.5% |
| DBV TECHNOLOGIES SA-SPON ADR | 28 | Q3 2021 | 1.8% |
| VBI VACCINES SHARES | 27 | Q1 2023 | 2.8% |
View Perceptive Advisors's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Immatics N.V. | June 06, 2024 | 8,170,846 | 7.9% |
| BIODESIX INC | May 13, 2024 | 6,673,880 | 5.6% |
| TRINITY BIOTECH PLC | May 01, 2024 | 56,000,000 | 26.8% |
| RHYTHM PHARMACEUTICALS, INC. | April 17, 2024 | 5,143,575 | 8.3% |
| VBI Vaccines Inc/BC | April 17, 2024 | 1,261,710 | 4.4% |
| Acrivon Therapeutics, Inc. | April 15, 2024 | 5,360,858 | 17.4% |
| Contineum Therapeutics, Inc. | April 15, 2024 | 1,566,669 | 8.5% |
| Landos Biopharma, Inc. | April 10, 2024 | 1,486,991 | 47.7% |
| PRECISION BIOSCIENCES INC | March 14, 2024 | 500,000 | 7.9% |
| ARTIVION, INC. | March 11, 2024 | 2,383,978 | 5.8% |
View Perceptive Advisors's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-10-10 |
| SC 13G | 2024-09-27 |
| SC 13D/A | 2024-09-24 |
| SC 13G | 2024-09-23 |
| N-PX | 2024-08-27 |
| 13F-HR/A | 2024-08-16 |
| SC 13D/A | 2024-08-15 |
| 13F-HR | 2024-08-14 |
| 4 | 2024-08-14 |
| SC 13D/A | 2024-08-14 |
View Perceptive Advisors's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.