Q3 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FOLD | Buy | AMICUS THERAPEUTICS INC | $336,745,870 | -3.1% | 27,692,917 | +0.1% | 11.23% | +11.7% |
| IMVT | Buy | IMMUNOVANT INC | $146,445,987 | +205.9% | 3,814,691 | +51.1% | 4.88% | +252.5% |
| Sell | ARCELLX INC | $142,299,291 | +12.0% | 3,965,978 | -1.3% | 4.75% | +29.1% | |
| Buy | NUVALENT INC | $113,244,842 | +22.4% | 2,463,451 | +12.2% | 3.78% | +41.0% | |
| Buy | SOLENO THERAPEUTICS INC | $90,729,734 | +857.9% | 3,074,542 | +39.3% | 3.03% | +1004.4% | |
| AKRO | Sell | AKERO THERAPEUTICS INC | $81,910,517 | -9.6% | 1,619,425 | -16.6% | 2.73% | +4.2% |
| INBX | Buy | INHIBRX INC | $78,099,508 | -17.0% | 4,256,104 | +17.4% | 2.60% | -4.3% |
| ARGX | Buy | ARGENX SEsponsored adr | $74,039,478 | +175.3% | 150,600 | +118.3% | 2.47% | +217.5% |
| PCVX | Sell | VAXCYTE INC | $68,453,446 | -15.1% | 1,342,751 | -16.8% | 2.28% | -2.1% |
| VRNA | Sell | VERONA PHARMA PLCsponsored ads | $65,317,311 | -29.7% | 4,007,197 | -8.9% | 2.18% | -19.0% |
| CBAY | Buy | CYMABAY THERAPEUTICS INC | $60,283,978 | +47.5% | 4,043,191 | +8.3% | 2.01% | +70.0% |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $54,431,367 | -44.9% | 11,962,938 | -14.8% | 1.82% | -36.5% |
| Sell | AMYLYX PHARMACEUTICALS INC | $49,233,265 | -53.2% | 2,688,873 | -44.8% | 1.64% | -46.0% | |
| MDT | Buy | MEDTRONIC PLC | $45,997,320 | +11.8% | 587,000 | +25.7% | 1.53% | +28.8% |
| Buy | ROIVANT SCIENCES LTD | $44,611,246 | +41.3% | 3,819,456 | +22.0% | 1.49% | +62.8% | |
| Buy | DISC MEDICINE INC | $42,077,214 | +27.6% | 895,641 | +20.6% | 1.40% | +47.0% | |
| New | APOGEE THERAPEUTICS INC | $38,934,291 | – | 1,827,901 | – | 1.30% | – | |
| CRNX | Sell | CRINETICS PHARMACEUTICALS IN | $37,583,389 | +7.1% | 1,263,732 | -35.1% | 1.25% | +23.5% |
| RVMD | New | REVOLUTION MEDICINES INC | $36,587,286 | – | 1,321,795 | – | 1.22% | – |
| SWTX | Sell | SPRINGWORKS THERAPEUTICS INC | $35,152,017 | -12.8% | 1,520,416 | -1.1% | 1.17% | +0.5% |
| AXSM | Buy | AXSOME THERAPEUTICS INC | $33,662,449 | +72.5% | 481,649 | +77.4% | 1.12% | +98.8% |
| HRMY | Buy | HARMONY BIOSCIENCES HLDGS IN | $32,648,948 | +4.1% | 996,306 | +11.8% | 1.09% | +19.9% |
| RAPT | Sell | RAPT THERAPEUTICS INC | $31,921,336 | -25.4% | 1,920,658 | -16.1% | 1.06% | -14.0% |
| RCKT | Buy | ROCKET PHARMACEUTICALS INC | $31,092,899 | +33.9% | 1,517,467 | +29.9% | 1.04% | +54.3% |
| New | TANGO THERAPEUTICS INC | $27,237,580 | – | 2,418,968 | – | 0.91% | – | |
| ADMA | Sell | ADMA BIOLOGICS INC | $25,003,862 | -43.1% | 6,984,319 | -41.3% | 0.83% | -34.4% |
| TMCI | Sell | TREACE MED CONCEPTS INC | $24,044,527 | -57.6% | 1,834,060 | -17.3% | 0.80% | -51.2% |
| COGT | Sell | COGENT BIOSCIENCES INC | $22,517,333 | -28.5% | 2,309,470 | -13.2% | 0.75% | -17.6% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $22,149,318 | +138.6% | 182,720 | +125.4% | 0.74% | +174.7% |
| MIRM | Buy | MIRUM PHARMACEUTICALS INC | $21,236,527 | +36.5% | 672,042 | +11.7% | 0.71% | +57.3% |
| Buy | ORCHESTRA BIOMED HLDGS INC | $21,207,816 | +47.6% | 2,432,089 | +18.5% | 0.71% | +70.0% | |
| XENE | Sell | XENON PHARMACEUTICALS INC | $21,093,800 | -55.2% | 617,500 | -49.5% | 0.70% | -48.3% |
| Buy | BIOHAVEN LTD | $19,554,838 | +154.8% | 751,820 | +134.3% | 0.65% | +193.7% | |
| MDGL | Sell | MADRIGAL PHARMACEUTICALS INC | $18,201,987 | -74.0% | 124,637 | -58.9% | 0.61% | -70.0% |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $17,914,725 | +89.9% | 159,242 | +59.2% | 0.60% | +119.0% |
| PTGX | Sell | PROTAGONIST THERAPEUTICS INC | $17,585,274 | -56.7% | 1,054,273 | -28.3% | 0.59% | -50.0% |
| New | RAYZEBIO INC | $17,245,071 | – | 776,805 | – | 0.58% | – | |
| CABA | Sell | CABALETTA BIO INC | $17,236,513 | -13.6% | 1,132,491 | -26.7% | 0.58% | -0.3% |
| VRDN | Sell | VIRIDIAN THERAPEUTICS INC | $15,511,885 | -63.3% | 1,011,205 | -43.1% | 0.52% | -57.7% |
| ESTA | Sell | ESTABLISHMENT LABS HLDGS INC | $13,625,905 | -53.3% | 277,683 | -34.7% | 0.46% | -46.1% |
| EOLS | New | EVOLUS INC | $13,580,221 | – | 1,485,801 | – | 0.45% | – |
| TCMD | Buy | TACTILE SYS TECHNOLOGY INC | $9,935,584 | -33.8% | 707,159 | +17.4% | 0.33% | -23.9% |
| NTRA | Sell | NATERA INC | $9,654,377 | -51.0% | 218,178 | -46.2% | 0.32% | -43.6% |
| Sell | ZYMEWORKS INC | $9,168,420 | -56.1% | 1,446,123 | -40.1% | 0.31% | -49.3% | |
| RYTM | New | RHYTHM PHARMACEUTICALS INC | $8,730,482 | – | 380,828 | – | 0.29% | – |
| CMAX | Buy | CAREMAX INC | $8,105,940 | -31.7% | 3,823,557 | +0.2% | 0.27% | -21.5% |
| PRTA | Sell | PROTHENA CORP PLC | $7,990,924 | -36.6% | 165,615 | -10.3% | 0.27% | -26.8% |
| OM | Sell | OUTSET MED INC | $7,202,310 | -63.5% | 661,977 | -26.6% | 0.24% | -58.0% |
| AKRO | New | AKERO THERAPEUTICS INCcall | $5,460,000 | – | 800,000 | – | 0.18% | – |
| TERN | New | TERNS PHARMACEUTICALS INC | $5,407,250 | – | 1,075,000 | – | 0.18% | – |
| NBTX | Sell | NANOBIOTIXsponsored ads | $4,856,828 | -9.6% | 555,066 | -47.6% | 0.16% | +3.8% |
| AXGN | Sell | AXOGEN INC | $4,379,490 | -67.3% | 875,898 | -40.2% | 0.15% | -62.3% |
| NVAX | New | NOVAVAX INCput | $3,772,520 | – | 1,300,000 | – | 0.13% | – |
| TVTX | Buy | TRAVERE THERAPEUTICS INC | $3,576,000 | +156.5% | 400,000 | +340.8% | 0.12% | +197.5% |
| SRPT | New | SAREPTA THERAPEUTICS INCcall | $3,130,000 | – | 100,000 | – | 0.10% | – |
| PNT | Buy | POINT BIOPHARMA GLOBAL INCput | $2,630,000 | +289.6% | 800,000 | +60.0% | 0.09% | +340.0% |
| EYPT | New | EYEPOINT PHARMACEUTICALS INCput | $2,512,500 | – | 750,000 | – | 0.08% | – |
| FBRX | New | FORTE BIOSCIENCES INC | $2,161,667 | – | 3,265,359 | – | 0.07% | – |
| ETNB | New | 89BIO INCcall | $1,620,000 | – | 400,000 | – | 0.05% | – |
| ACRS | New | ACLARIS THERAPEUTICS INCput | $1,450,000 | – | 500,000 | – | 0.05% | – |
| New | AEGLEA BIOTHERAPEUTICS INC | $993,671 | – | 81,116 | – | 0.03% | – | |
| VERU | Buy | VERU INC | $783,622 | +632.7% | 1,089,878 | +1112.6% | 0.03% | +766.7% |
| VKTX | New | VIKING THERAPEUTICS INCcall | $240,000 | – | 300,000 | – | 0.01% | – |
| Sell | LEAP THERAPEUTICS INC | $62,059 | -96.6% | 44,971 | -92.3% | 0.00% | -96.2% | |
| APLS | New | APELLIS PHARMACEUTICALS INCput | $72,500 | – | 100,000 | – | 0.00% | – |
| BTAI | Exit | BIOXCEL THERAPEUTICS INCcall | $0 | – | -439,500 | – | 0.00% | – |
| XBI | Exit | SPDR SER TRput | $0 | – | -150,000 | – | -0.00% | – |
| VRNA | Exit | VERONA PHARMA PLCcall | $0 | – | -500,000 | – | -0.02% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INCcall | $0 | – | -200,000 | – | -0.02% | – |
| QTRX | Exit | QUANTERIX CORP | $0 | – | -130,000 | – | -0.08% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -168,000 | – | -0.19% | – |
| VKTX | Exit | VIKING THERAPEUTICS INC | $0 | – | -441,147 | – | -0.21% | – |
| TERN | Exit | TERNS PHARMACEUTICALS INCput | $0 | – | -1,075,000 | – | -0.27% | – |
| ITCI | Exit | INTRA-CELLULAR THERAPIES INC | $0 | – | -245,800 | – | -0.45% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -263,207 | – | -0.66% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -719,103 | – | -0.75% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -145,000 | – | -0.79% | – |
| VIR | Exit | VIR BIOTECHNOLOGY INC | $0 | – | -1,958,264 | – | -1.39% | – |
| RETA | Exit | REATA PHARMACEUTICALS INCcl a | $0 | – | -670,206 | – | -1.98% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -812,037 | – | -2.14% | – |
Q2 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FOLD | New | AMICUS THERAPEUTICS INC | $347,446,237 | – | 27,662,917 | – | 10.06% | – |
| CERE | New | CEREVEL THERAPEUTICS HLDNG I | $320,709,759 | – | 10,088,385 | – | 9.28% | – |
| New | LIANBIOsponsored ads | $131,233,268 | – | 57,558,451 | – | 3.80% | – | |
| New | ARCELLX INC | $126,998,473 | – | 4,016,397 | – | 3.68% | – | |
| New | AMYLYX PHARMACEUTICALS INC | $105,130,433 | – | 4,873,919 | – | 3.04% | – | |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $98,816,326 | – | 14,036,410 | – | 2.86% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $95,227,213 | – | 11,350,085 | – | 2.76% | – |
| INBX | New | INHIBRX INC | $94,083,765 | – | 3,624,182 | – | 2.72% | – |
| VRNA | New | VERONA PHARMA PLCsponsored ads | $92,955,032 | – | 4,397,116 | – | 2.69% | – |
| New | NUVALENT INC | $92,555,602 | – | 2,194,821 | – | 2.68% | – | |
| AKRO | New | AKERO THERAPEUTICS INC | $90,610,116 | – | 1,940,675 | – | 2.62% | – |
| PCVX | New | VAXCYTE INC | $80,609,253 | – | 1,614,122 | – | 2.33% | – |
| MGTX | New | MEIRAGTX HLDGS PLC | $76,145,012 | – | 11,331,103 | – | 2.20% | – |
| APLS | New | APELLIS PHARMACEUTICALS INC | $73,976,570 | – | 812,037 | – | 2.14% | – |
| MDGL | New | MADRIGAL PHARMACEUTICALS INC | $69,989,997 | – | 302,987 | – | 2.03% | – |
| RETA | New | REATA PHARMACEUTICALS INCcl a | $68,334,204 | – | 670,206 | – | 1.98% | – |
| TMCI | New | TREACE MED CONCEPTS INC | $56,717,255 | – | 2,217,250 | – | 1.64% | – |
| LYRA | New | LYRA THERAPEUTICS INC | $52,433,579 | – | 12,757,562 | – | 1.52% | – |
| VIR | New | VIR BIOTECHNOLOGY INC | $48,036,216 | – | 1,958,264 | – | 1.39% | – |
| IMVT | New | IMMUNOVANT INC | $47,876,164 | – | 2,523,783 | – | 1.39% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $47,100,015 | – | 1,223,377 | – | 1.36% | – |
| ADMA | New | ADMA BIOLOGICS INC | $43,911,941 | – | 11,900,255 | – | 1.27% | – |
| RAPT | New | RAPT THERAPEUTICS INC | $42,794,819 | – | 2,288,493 | – | 1.24% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $42,260,223 | – | 1,776,386 | – | 1.22% | – |
| MDT | New | MEDTRONIC PLC | $41,142,700 | – | 467,000 | – | 1.19% | – |
| CBAY | New | CYMABAY THERAPEUTICS INC | $40,879,142 | – | 3,733,255 | – | 1.18% | – |
| PTGX | New | PROTAGONIST THERAPEUTICS INC | $40,594,799 | – | 1,469,761 | – | 1.18% | – |
| SWTX | New | SPRINGWORKS THERAPEUTICS INC | $40,311,440 | – | 1,537,431 | – | 1.17% | – |
| IMTX | New | IMMATICS N.V | $40,291,910 | – | 3,491,500 | – | 1.17% | – |
| New | ACRIVON THERAPEUTICS INC | $38,981,840 | – | 3,007,858 | – | 1.13% | – | |
| NAUT | New | NAUTILUS BIOTECHNOLOGY INC | $35,260,154 | – | 9,111,151 | – | 1.02% | – |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $35,083,805 | – | 1,946,937 | – | 1.02% | – |
| New | DISC MEDICINE INC | $32,982,007 | – | 742,838 | – | 0.96% | – | |
| New | ROIVANT SCIENCES LTD | $31,567,899 | – | 3,131,736 | – | 0.91% | – | |
| COGT | New | COGENT BIOSCIENCES INC | $31,488,125 | – | 2,659,470 | – | 0.91% | – |
| HRMY | New | HARMONY BIOSCIENCES HLDGS IN | $31,367,310 | – | 891,370 | – | 0.91% | – |
| BBIO | New | BRIDGEBIO PHARMA INC | $30,081,647 | – | 1,748,933 | – | 0.87% | – |
| ESTA | New | ESTABLISHMENT LABS HLDGS INC | $29,154,036 | – | 424,924 | – | 0.84% | – |
| VRCA | New | VERRICA PHARMACEUTICALS INC | $29,074,931 | – | 5,038,983 | – | 0.84% | – |
| ILMN | New | ILLUMINA INC | $27,186,050 | – | 145,000 | – | 0.79% | – |
| ARGX | New | ARGENX SEsponsored adr | $26,891,370 | – | 69,000 | – | 0.78% | – |
| MRTX | New | MIRATI THERAPEUTICS INC | $25,981,191 | – | 719,103 | – | 0.75% | – |
| RLAY | New | RELAY THERAPEUTICS INC | $24,405,298 | – | 1,943,097 | – | 0.71% | – |
| TARS | New | TARSUS PHARMACEUTICALS INC | $23,426,237 | – | 1,296,416 | – | 0.68% | – |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $23,215,373 | – | 1,168,363 | – | 0.67% | – |
| BMRN | New | BIOMARIN PHARMACEUTICAL INC | $22,814,783 | – | 263,207 | – | 0.66% | – |
| New | ZYMEWORKS INC | $20,876,244 | – | 2,416,232 | – | 0.60% | – | |
| CABA | New | CABALETTA BIO INC | $19,945,950 | – | 1,545,000 | – | 0.58% | – |
| OM | New | OUTSET MED INC | $19,734,613 | – | 902,360 | – | 0.57% | – |
| NTRA | New | NATERA INC | $19,720,390 | – | 405,269 | – | 0.57% | – |
| AXSM | New | AXSOME THERAPEUTICS INC | $19,509,487 | – | 271,493 | – | 0.56% | – |
| New | SOLID BIOSCIENCES INC | $18,318,688 | – | 3,495,933 | – | 0.53% | – | |
| New | ASTRIA THERAPEUTICS INC | $18,238,218 | – | 2,189,462 | – | 0.53% | – | |
| CRY | New | ARTIVION INC | $16,009,941 | – | 931,352 | – | 0.46% | – |
| BMEA | New | BIOMEA FUSION INC | $15,725,879 | – | 716,441 | – | 0.46% | – |
| ITCI | New | INTRA-CELLULAR THERAPIES INC | $15,564,056 | – | 245,800 | – | 0.45% | – |
| MIRM | New | MIRUM PHARMACEUTICALS INC | $15,562,512 | – | 601,566 | – | 0.45% | – |
| TCMD | New | TACTILE SYS TECHNOLOGY INC | $15,017,259 | – | 602,377 | – | 0.44% | – |
| New | ORCHESTRA BIOMED HLDGS INC | $14,370,076 | – | 2,052,868 | – | 0.42% | – | |
| ATHA | New | ATHIRA PHARMA INC | $14,151,970 | – | 4,797,278 | – | 0.41% | – |
| AXGN | New | AXOGEN INC | $13,373,825 | – | 1,464,822 | – | 0.39% | – |
| FUSN | New | FUSION PHARMACEUTICALS INC | $12,849,014 | – | 2,751,395 | – | 0.37% | – |
| PRTA | New | PROTHENA CORP PLC | $12,605,512 | – | 184,615 | – | 0.36% | – |
| CMAX | New | CAREMAX INC | $11,872,126 | – | 3,817,404 | – | 0.34% | – |
| New | SOLENO THERAPEUTICS INC | $9,471,260 | – | 2,207,753 | – | 0.27% | – | |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $9,434,715 | – | 100,050 | – | 0.27% | – |
| TERN | New | TERNS PHARMACEUTICALS INCput | $9,406,250 | – | 1,075,000 | – | 0.27% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $9,284,594 | – | 81,074 | – | 0.27% | – |
| New | BIOHAVEN LTD | $7,674,014 | – | 320,820 | – | 0.22% | – | |
| VKTX | New | VIKING THERAPEUTICS INC | $7,150,993 | – | 441,147 | – | 0.21% | – |
| XFOR | New | X4 PHARMACEUTICALS INC | $6,878,181 | – | 3,545,454 | – | 0.20% | – |
| ISEE | New | IVERIC BIO INC | $6,609,120 | – | 168,000 | – | 0.19% | – |
| New | LANDOS BIOPHARMA INC | $6,255,771 | – | 1,486,991 | – | 0.18% | – | |
| New | TYRA BIOSCIENCES INC | $6,130,800 | – | 360,000 | – | 0.18% | – | |
| NBTX | New | NANOBIOTIXsponsored ads | $5,373,186 | – | 1,059,800 | – | 0.16% | – |
| New | VBI VACCINES INC CDA | $4,544,657 | – | 1,381,355 | – | 0.13% | – | |
| New | ACELYRIN INC | $4,180,000 | – | 200,000 | – | 0.12% | – | |
| New | SOMALOGIC INC | $3,465,000 | – | 1,500,000 | – | 0.10% | – | |
| KRON | New | KRONOS BIO INC | $3,014,721 | – | 1,752,745 | – | 0.09% | – |
| QTRX | New | QUANTERIX CORP | $2,931,500 | – | 130,000 | – | 0.08% | – |
| New | ENVVENO MEDICAL CORPORATION | $2,407,374 | – | 781,615 | – | 0.07% | – | |
| OMIC | New | SINGULAR GENOMICS SYSTEMS IN | $1,961,468 | – | 2,363,214 | – | 0.06% | – |
| New | LEAP THERAPEUTICS INC | $1,836,474 | – | 586,733 | – | 0.05% | – | |
| ARQT | New | ARCUTIS BIOTHERAPEUTICS INCput | $1,417,500 | – | 300,000 | – | 0.04% | – |
| TVTX | New | TRAVERE THERAPEUTICS INC | $1,393,889 | – | 90,748 | – | 0.04% | – |
| PNT | New | POINT BIOPHARMA GLOBAL INCput | $675,000 | – | 500,000 | – | 0.02% | – |
| MRTX | New | MIRATI THERAPEUTICS INCcall | $690,000 | – | 200,000 | – | 0.02% | – |
| VRNA | New | VERONA PHARMA PLCcall | $675,000 | – | 500,000 | – | 0.02% | – |
| XBI | New | SPDR SER TRput | $137,500 | – | 150,000 | – | 0.00% | – |
| VERU | New | VERU INC | $106,955 | – | 89,878 | – | 0.00% | – |
| New | MOTUS GI HLDGS INC | $60,318 | – | 90,027 | – | 0.00% | – | |
| New | EQRX INC*w exp 12/17/202 | $42,500 | – | 250,000 | – | 0.00% | – | |
| CMAXW | New | CAREMAX INC*w exp 06/08/202 | $23,400 | – | 60,000 | – | 0.00% | – |
| BTAI | New | BIOXCEL THERAPEUTICS INCcall | $10,987 | – | 439,500 | – | 0.00% | – |
| New | SURROZEN INC*w exp 08/01/203 | $10,000 | – | 166,666 | – | 0.00% | – |
Q4 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Exit | SURROZEN INC | $0 | – | -6,017 | – | 0.00% | – | |
| Exit | SURROZEN INC*w exp 08/01/203 | $0 | – | -166,666 | – | -0.00% | – | |
| CMAXW | Exit | CAREMAX INC*w exp 06/08/202 | $0 | – | -60,000 | – | -0.00% | – |
| Exit | NEPTUNE WELLNESS SOLUTIONS I | $0 | – | -57,142 | – | -0.00% | – | |
| Exit | AGILE THERAPEUTICS INC | $0 | – | -532,361 | – | -0.01% | – | |
| Exit | MOTUS GI HLDGS INC | $0 | – | -90,027 | – | -0.01% | – | |
| Exit | EQRX INC*w exp 12/17/202 | $0 | – | -250,000 | – | -0.01% | – | |
| Exit | ICOSAVAX INC | $0 | – | -93,591 | – | -0.01% | – | |
| PRVB | Exit | PROVENTION BIO INC | $0 | – | -110,728 | – | -0.01% | – |
| Exit | SONENDO INC | $0 | – | -612,204 | – | -0.02% | – | |
| Exit | HYPERFINE INC | $0 | – | -927,388 | – | -0.02% | – | |
| TARA | Exit | PROTARA THERAPEUTICS INC | $0 | – | -290,051 | – | -0.02% | – |
| Exit | DARIOHEALTH CORP | $0 | – | -327,869 | – | -0.04% | – | |
| Exit | PEAR THERAPEUTICS INC | $0 | – | -900,548 | – | -0.05% | – | |
| TVTX | Exit | TRAVERE THERAPEUTICS INC | $0 | – | -90,748 | – | -0.06% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -294,118 | – | -0.07% | – |
| Exit | SCIENCE 37 HOLDINGS INC | $0 | – | -1,500,000 | – | -0.07% | – | |
| QTNT | Exit | QUOTIENT LTD | $0 | – | -16,200,818 | – | -0.07% | – |
| RETA | Exit | REATA PHARMACEUTICALS INCcl a | $0 | – | -100,000 | – | -0.07% | – |
| CLOV | Exit | CLOVER HEALTH INVESTMENTS CO | $0 | – | -1,500,000 | – | -0.07% | – |
| PSTX | Exit | POSEIDA THERAPEUTICS INC | $0 | – | -750,000 | – | -0.08% | – |
| Exit | ABSCI CORPORATION | $0 | – | -894,346 | – | -0.08% | – | |
| Exit | PYXIS ONCOLOGY INC | $0 | – | -1,528,812 | – | -0.09% | – | |
| YMAB | Exit | Y-MABS THERAPEUTICS INC | $0 | – | -212,018 | – | -0.09% | – |
| Exit | COHERUS BIOSCIENCES INCnote 1.500% 4/1 | $0 | – | -4,500,000 | – | -0.10% | – | |
| NBTX | Exit | NANOBIOTIXsponsored ads | $0 | – | -1,059,800 | – | -0.11% | – |
| HCAT | Exit | HEALTH CATALYST INC | $0 | – | -389,962 | – | -0.11% | – |
| PNT | Exit | POINT BIOPHARMA GLOBAL INC | $0 | – | -500,000 | – | -0.11% | – |
| ABOS | Exit | ACUMEN PHARMACEUTICALS INC | $0 | – | -400,000 | – | -0.12% | – |
| ATNX | Exit | ATHENEX INC | $0 | – | -15,532,467 | – | -0.12% | – |
| CTIC | Exit | CTI BIOPHARMA CORP | $0 | – | -735,165 | – | -0.12% | – |
| Exit | TYRA BIOSCIENCES INC | $0 | – | -494,403 | – | -0.13% | – | |
| Exit | SOMALOGIC INC | $0 | – | -1,500,000 | – | -0.13% | – | |
| Exit | SEMA4 HOLDINGS CORP | $0 | – | -5,000,000 | – | -0.13% | – | |
| Exit | ENVVENO MEDICAL CORPORATION | $0 | – | -781,615 | – | -0.14% | – | |
| NARI | Exit | INARI MED INC | $0 | – | -70,000 | – | -0.15% | – |
| TCDA | Exit | TRICIDA INCput | $0 | – | -500,000 | – | -0.15% | – |
| NTRA | Exit | NATERA INC | $0 | – | -120,000 | – | -0.15% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -341,239 | – | -0.16% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -310,500 | – | -0.18% | – |
| SLDB | Exit | SOLID BIOSCIENCES INC | $0 | – | -13,412,552 | – | -0.18% | – |
| LPTX | Exit | LEAP THERAPEUTICS INC | $0 | – | -7,472,148 | – | -0.19% | – |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -766,231 | – | -0.20% | – |
| NVRO | Exit | NEVRO CORP | $0 | – | -150,000 | – | -0.20% | – |
| Exit | ISOPLEXIS CORP | $0 | – | -4,095,498 | – | -0.20% | – | |
| KRON | Exit | KRONOS BIO INC | $0 | – | -2,156,151 | – | -0.21% | – |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -500,000 | – | -0.23% | – |
| OMIC | Exit | SINGULAR GENOMICS SYSTEMS IN | $0 | – | -3,536,274 | – | -0.26% | – |
| LRMR | Exit | LARIMAR THERAPEUTICS INC | $0 | – | -2,860,000 | – | -0.27% | – |
| LABP | Exit | LANDOS BIOPHARMA INC | $0 | – | -14,869,915 | – | -0.28% | – |
| CCXI | Exit | CHEMOCENTRYX INC | $0 | – | -192,680 | – | -0.29% | – |
| MORF | Exit | MORPHIC HLDG INC | $0 | – | -363,197 | – | -0.30% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -100,050 | – | -0.31% | – |
| Exit | PROCEPT BIOROBOTICS CORP | $0 | – | -263,720 | – | -0.32% | – | |
| AXGN | Exit | AXOGEN INC | $0 | – | -949,626 | – | -0.33% | – |
| Exit | ASTRIA THERAPEUTICS INC | $0 | – | -1,281,197 | – | -0.34% | – | |
| RAIN | Exit | RAIN THERAPEUTICS INC | $0 | – | -2,483,619 | – | -0.35% | – |
| Exit | HILLEVAX INC | $0 | – | -764,907 | – | -0.38% | – | |
| Exit | DICE THERAPEUTICS INC | $0 | – | -687,424 | – | -0.40% | – | |
| PRTA | Exit | PROTHENA CORP PLC | $0 | – | -230,000 | – | -0.40% | – |
| ATHA | Exit | ATHIRA PHARMA INC | $0 | – | -4,797,278 | – | -0.41% | – |
| CNCE | Exit | CONCERT PHARMACEUTICALS INC | $0 | – | -2,150,641 | – | -0.42% | – |
| AKRO | Exit | AKERO THERAPEUTICS INC | $0 | – | -430,000 | – | -0.42% | – |
| VRCA | Exit | VERRICA PHARMACEUTICALS INC | $0 | – | -5,038,983 | – | -0.43% | – |
| CHRS | Exit | COHERUS BIOSCIENCES INC | $0 | – | -1,667,123 | – | -0.46% | – |
| CRY | Exit | ARTIVION INC | $0 | – | -1,204,229 | – | -0.48% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INC | $0 | – | -1,697,033 | – | -0.49% | – |
| RCUS | Exit | ARCUS BIOSCIENCES INC | $0 | – | -666,477 | – | -0.51% | – |
| HRMY | Exit | HARMONY BIOSCIENCES HLDGS IN | $0 | – | -411,804 | – | -0.53% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -1,034,169 | – | -0.54% | – |
| OM | Exit | OUTSET MED INC | $0 | – | -1,168,630 | – | -0.54% | – |
| Exit | CYTEK BIOSCIENCES INC | $0 | – | -1,289,534 | – | -0.55% | – | |
| NAUT | Exit | NAUTILUS BIOTECHNOLOGY INC | $0 | – | -9,111,151 | – | -0.56% | – |
| MDGL | Exit | MADRIGAL PHARMACEUTICALS INC | $0 | – | -331,023 | – | -0.62% | – |
| RVNC | Exit | REVANCE THERAPEUTICS INC | $0 | – | -808,671 | – | -0.63% | – |
| TARS | Exit | TARSUS PHARMACEUTICALS INC | $0 | – | -1,296,416 | – | -0.64% | – |
| CMAX | Exit | CAREMAX INC | $0 | – | -3,394,939 | – | -0.70% | – |
| IMTX | Exit | IMMATICS N.V | $0 | – | -2,500,000 | – | -0.73% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -366,400 | – | -0.73% | – |
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -1,220,575 | – | -0.73% | – |
| ADMA | Exit | ADMA BIOLOGICS INC | $0 | – | -10,933,387 | – | -0.77% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -4,400,099 | – | -0.78% | – |
| EW | Exit | EDWARDS LIFESCIENCES CORP | $0 | – | -330,000 | – | -0.79% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -253,000 | – | -0.81% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -336,481 | – | -0.83% | – |
| ESTA | Exit | ESTABLISHMENT LABS HLDGS INC | $0 | – | -578,253 | – | -0.92% | – |
| Exit | NUVALENT INC | $0 | – | -1,655,007 | – | -0.93% | – | |
| TMCI | Exit | TREACE MED CONCEPTS INC | $0 | – | -1,601,979 | – | -1.03% | – |
| VBIV | Exit | VBI VACCINES INC CDA | $0 | – | -52,335,002 | – | -1.08% | – |
| RAPT | Exit | RAPT THERAPEUTICS INC | $0 | – | -1,713,134 | – | -1.20% | – |
| SGEN | Exit | SEAGEN INC | $0 | – | -316,544 | – | -1.26% | – |
| RLAY | Exit | RELAY THERAPEUTICS INC | $0 | – | -1,943,097 | – | -1.26% | – |
| VERU | Exit | VERU INC | $0 | – | -3,893,000 | – | -1.30% | – |
| ALBO | Exit | ALBIREO PHARMA INC | $0 | – | -2,360,139 | – | -1.33% | – |
| LYRA | Exit | LYRA THERAPEUTICS INC | $0 | – | -9,146,730 | – | -1.33% | – |
| Exit | TRAVERE THERAPEUTICS INCnote 2.250% 3/0 | $0 | – | -45,000,000 | – | -1.33% | – | |
| Exit | ARCELLX INC | $0 | – | -2,465,405 | – | -1.34% | – | |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -3,207,441 | – | -1.39% | – |
| VRNA | Exit | VERONA PHARMA PLCsponsored ads | $0 | – | -5,047,264 | – | -1.50% | – |
| INBX | Exit | INHIBRX INC | $0 | – | -2,887,860 | – | -1.50% | – |
| MGTX | Exit | MEIRAGTX HLDGS PLC | $0 | – | -6,963,277 | – | -1.70% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INC | $0 | – | -11,350,085 | – | -1.76% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -2,122,535 | – | -2.22% | – |
| RXDX | Exit | PROMETHEUS BIOSCIENCES INC | $0 | – | -1,468,512 | – | -2.52% | – |
| RLMD | Exit | RELMADA THERAPEUTICS INC | $0 | – | -2,383,478 | – | -2.56% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -10,248,624 | – | -2.85% | – |
| SWTX | Exit | SPRINGWORKS THERAPEUTICS INC | $0 | – | -3,470,563 | – | -2.87% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS IN | $0 | – | -5,321,032 | – | -3.03% | – |
| BLU | Exit | BELLUS HEALTH INC NEW | $0 | – | -10,247,073 | – | -3.14% | – |
| Exit | CINCOR PHARMA INC | $0 | – | -3,306,649 | – | -3.15% | – | |
| Exit | LIANBIOsponsored ads | $0 | – | -57,558,451 | – | -3.34% | – | |
| Exit | AMYLYX PHARMACEUTICALS INC | $0 | – | -5,472,033 | – | -4.47% | – | |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -2,322,247 | – | -4.59% | – |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -6,511,727 | – | -5.34% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -2,784,796 | – | -5.64% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -27,372,917 | – | -8.29% | – |
Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FOLD | Buy | AMICUS THERAPEUTICS INC | $285,773,000 | -1.1% | 27,372,917 | +1.8% | 8.29% | -8.3% |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $194,490,000 | +1.1% | 2,784,796 | -2.9% | 5.64% | -6.4% |
| CERE | Buy | CEREVEL THERAPEUTICS HLDNG I | $184,021,000 | +36.8% | 6,511,727 | +28.0% | 5.34% | +26.8% |
| GBT | Sell | GLOBAL BLOOD THERAPEUTICS IN | $158,145,000 | +64.2% | 2,322,247 | -23.0% | 4.59% | +52.1% |
| Buy | AMYLYX PHARMACEUTICALS INC | $154,038,000 | +125.9% | 5,472,033 | +54.6% | 4.47% | +109.3% | |
| Buy | LIANBIOsponsored ads | $115,116,000 | -5.8% | 57,558,451 | +1.8% | 3.34% | -12.7% | |
| Buy | CINCOR PHARMA INC | $108,524,000 | +148.4% | 3,306,649 | +42.6% | 3.15% | +130.3% | |
| BLU | Buy | BELLUS HEALTH INC NEW | $108,209,000 | +111.6% | 10,247,073 | +85.2% | 3.14% | +96.0% |
| SWTX | Sell | SPRINGWORKS THERAPEUTICS INC | $99,015,000 | +4.0% | 3,470,563 | -10.3% | 2.87% | -3.6% |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $98,181,000 | -24.8% | 10,248,624 | -13.3% | 2.85% | -30.3% |
| RLMD | Buy | RELMADA THERAPEUTICS INC | $88,236,000 | +3729.7% | 2,383,478 | +1864.1% | 2.56% | +3456.9% |
| RXDX | Sell | PROMETHEUS BIOSCIENCES INC | $86,657,000 | +82.5% | 1,468,512 | -12.7% | 2.52% | +69.1% |
| ALDX | Buy | ALDEYRA THERAPEUTICS INC | $60,609,000 | +53.4% | 11,350,085 | +14.6% | 1.76% | +42.1% |
| INBX | Buy | INHIBRX INC | $51,837,000 | +138.5% | 2,887,860 | +50.8% | 1.50% | +120.9% |
| VRNA | Buy | VERONA PHARMA PLCsponsored ads | $51,583,000 | +322.3% | 5,047,264 | +73.1% | 1.50% | +290.9% |
| COGT | Buy | COGENT BIOSCIENCES INC | $47,855,000 | +71.8% | 3,207,441 | +3.8% | 1.39% | +59.1% |
| Buy | ARCELLX INC | $46,276,000 | +124.1% | 2,465,405 | +115.9% | 1.34% | +107.6% | |
| VERU | Buy | VERU INC | $44,847,000 | +13.4% | 3,893,000 | +11.2% | 1.30% | +5.1% |
| SGEN | Buy | SEAGEN INC | $43,313,000 | +9.3% | 316,544 | +41.3% | 1.26% | +1.3% |
| RAPT | Sell | RAPT THERAPEUTICS INC | $41,218,000 | +18.0% | 1,713,134 | -10.5% | 1.20% | +9.3% |
| TMCI | Buy | TREACE MED CONCEPTS INC | $35,356,000 | +162.0% | 1,601,979 | +70.2% | 1.03% | +142.6% |
| ESTA | Buy | ESTABLISHMENT LABS HLDGS INC | $31,578,000 | +43.1% | 578,253 | +42.5% | 0.92% | +32.6% |
| BMRN | Buy | BIOMARIN PHARMACEUTICAL INC | $28,523,000 | +91.2% | 336,481 | +86.9% | 0.83% | +77.3% |
| SRPT | New | SAREPTA THERAPEUTICS INC | $27,967,000 | – | 253,000 | – | 0.81% | – |
| EW | New | EDWARDS LIFESCIENCES CORP | $27,268,000 | – | 330,000 | – | 0.79% | – |
| ZYME | Buy | ZYMEWORKS INC | $27,060,000 | +23.6% | 4,400,099 | +6.5% | 0.78% | +14.4% |
| ADMA | Sell | ADMA BIOLOGICS INC | $26,568,000 | +16.5% | 10,933,387 | -5.1% | 0.77% | +8.0% |
| VRDN | Buy | VIRIDIAN THERAPEUTICS INC | $25,034,000 | +122.6% | 1,220,575 | +25.6% | 0.73% | +106.5% |
| APLS | Buy | APELLIS PHARMACEUTICALS INC | $25,025,000 | +72.2% | 366,400 | +14.0% | 0.73% | +59.6% |
| CMAX | Buy | CAREMAX INC | $24,070,000 | +121.0% | 3,394,939 | +13.2% | 0.70% | +105.0% |
| RVNC | Buy | REVANCE THERAPEUTICS INC | $21,834,000 | +176.0% | 808,671 | +41.2% | 0.63% | +155.6% |
| MDGL | Sell | MADRIGAL PHARMACEUTICALS INC | $21,513,000 | -18.2% | 331,023 | -9.9% | 0.62% | -24.3% |
| New | CYTEK BIOSCIENCES INC | $18,982,000 | – | 1,289,534 | – | 0.55% | – | |
| OM | Buy | OUTSET MED INC | $18,616,000 | +25.4% | 1,168,630 | +17.0% | 0.54% | +16.1% |
| ISEE | Sell | IVERIC BIO INC | $18,553,000 | -7.6% | 1,034,169 | -50.5% | 0.54% | -14.5% |
| RCUS | New | ARCUS BIOSCIENCES INC | $17,435,000 | – | 666,477 | – | 0.51% | – |
| CRY | Buy | ARTIVION INC | $16,667,000 | -5.0% | 1,204,229 | +29.5% | 0.48% | -12.0% |
| CHRS | Sell | COHERUS BIOSCIENCES INC | $16,021,000 | -39.3% | 1,667,123 | -54.3% | 0.46% | -43.8% |
| AKRO | New | AKERO THERAPEUTICS INC | $14,642,000 | – | 430,000 | – | 0.42% | – |
| Sell | DICE THERAPEUTICS INC | $13,941,000 | -14.6% | 687,424 | -34.6% | 0.40% | -20.7% | |
| PRTA | New | PROTHENA CORP PLC | $13,945,000 | – | 230,000 | – | 0.40% | – |
| AXGN | New | AXOGEN INC | $11,320,000 | – | 949,626 | – | 0.33% | – |
| Sell | PROCEPT BIOROBOTICS CORP | $10,934,000 | -55.4% | 263,720 | -64.8% | 0.32% | -58.7% | |
| NBIX | Sell | NEUROCRINE BIOSCIENCES INC | $10,626,000 | -72.6% | 100,050 | -74.9% | 0.31% | -74.7% |
| CCXI | Sell | CHEMOCENTRYX INC | $9,954,000 | -9.1% | 192,680 | -56.4% | 0.29% | -15.7% |
| LRMR | New | LARIMAR THERAPEUTICS INC | $9,152,000 | – | 2,860,000 | – | 0.27% | – |
| RCKT | Sell | ROCKET PHARMACEUTICALS INC | $7,980,000 | -50.3% | 500,000 | -57.2% | 0.23% | -53.9% |
| KRON | Sell | KRONOS BIO INC | $7,223,000 | -18.0% | 2,156,151 | -10.9% | 0.21% | -23.9% |
| NVRO | New | NEVRO CORP | $6,990,000 | – | 150,000 | – | 0.20% | – |
| LPTX | Sell | LEAP THERAPEUTICS INC | $6,575,000 | -28.1% | 7,472,148 | -6.0% | 0.19% | -33.2% |
| RVMD | New | REVOLUTION MEDICINES INC | $6,123,000 | – | 310,500 | – | 0.18% | – |
| NTRA | New | NATERA INC | $5,258,000 | – | 120,000 | – | 0.15% | – |
| TCDA | New | TRICIDA INCput | $5,240,000 | – | 500,000 | – | 0.15% | – |
| NARI | New | INARI MED INC | $5,085,000 | – | 70,000 | – | 0.15% | – |
| CTIC | New | CTI BIOPHARMA CORP | $4,279,000 | – | 735,165 | – | 0.12% | – |
| ATNX | Buy | ATHENEX INC | $4,178,000 | -24.6% | 15,532,467 | +14.8% | 0.12% | -30.5% |
| ABOS | Sell | ACUMEN PHARMACEUTICALS INC | $4,012,000 | +67.9% | 400,000 | -21.3% | 0.12% | +54.7% |
| PNT | Sell | POINT BIOPHARMA GLOBAL INC | $3,865,000 | -47.2% | 500,000 | -53.4% | 0.11% | -51.1% |
| HCAT | Sell | HEALTH CATALYST INC | $3,783,000 | -43.9% | 389,962 | -16.2% | 0.11% | -47.9% |
| PSTX | New | POSEIDA THERAPEUTICS INC | $2,648,000 | – | 750,000 | – | 0.08% | – |
| RETA | New | REATA PHARMACEUTICALS INCcl a | $2,513,000 | – | 100,000 | – | 0.07% | – |
| TVTX | Sell | TRAVERE THERAPEUTICS INC | $2,236,000 | -83.8% | 90,748 | -84.1% | 0.06% | -85.0% |
| Sell | HYPERFINE INC | $751,000 | -70.3% | 927,388 | -18.2% | 0.02% | -72.2% | |
| Sell | SONENDO INC | $655,000 | -41.3% | 612,204 | -5.6% | 0.02% | -45.7% | |
| Sell | ICOSAVAX INC | $296,000 | -95.0% | 93,591 | -91.0% | 0.01% | -95.2% | |
| New | MOTUS GI HLDGS INC | $221,000 | – | 90,027 | – | 0.01% | – | |
| MOTS | Exit | MOTUS GI HLDGS INC | $0 | – | -1,800,542 | – | -0.02% | – |
| ZY | Exit | ZYMERGEN INC | $0 | – | -883,332 | – | -0.03% | – |
| RACE | Exit | FERRARI N V | $0 | – | -6,200 | – | -0.04% | – |
| FUSN | Exit | FUSION PHARMACEUTICALS INC | $0 | – | -1,052,445 | – | -0.08% | – |
| SAVA | Exit | CASSAVA SCIENCES INCput | $0 | – | -100,000 | – | -0.09% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -1,227,202 | – | -0.11% | – |
| NUVB | Exit | NUVATION BIO INC | $0 | – | -1,769,701 | – | -0.18% | – |
| XBI | Exit | SPDR SER TRput | $0 | – | -100,000 | – | -0.23% | – |
| PRVA | Exit | PRIVIA HEALTH GROUP INC | $0 | – | -273,423 | – | -0.25% | – |
| DAWN | Exit | DAY ONE BIOPHARMACEUTICALS I | $0 | – | -556,047 | – | -0.31% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -172,991 | – | -0.79% | – |
| LLY | Exit | LILLY ELI & CO | $0 | – | -100,000 | – | -1.02% | – |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| New | TRAVERE THERAPEUTICS INCnote 2.250% 3/0 | $455,940,000 | – | 45,000,000 | – | 14.28% | – | |
| FOLD | New | AMICUS THERAPEUTICS INC | $288,858,000 | – | 26,895,532 | – | 9.05% | – |
| MRTX | New | MIRATI THERAPEUTICS INC | $192,453,000 | – | 2,866,863 | – | 6.03% | – |
| CERE | New | CEREVEL THERAPEUTICS HLDNG I | $134,493,000 | – | 5,086,727 | – | 4.21% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $130,562,000 | – | 11,826,299 | – | 4.09% | – |
| New | LIANBIOsponsored ads | $122,170,000 | – | 56,560,211 | – | 3.83% | – | |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $99,237,000 | – | 5,321,032 | – | 3.11% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $96,331,000 | – | 3,015,054 | – | 3.02% | – |
| SWTX | New | SPRINGWORKS THERAPEUTICS INC | $95,217,000 | – | 3,867,446 | – | 2.98% | – |
| New | AMYLYX PHARMACEUTICALS INC | $68,188,000 | – | 3,540,408 | – | 2.14% | – | |
| XENE | New | XENON PHARMACEUTICALS INC | $64,568,000 | – | 2,122,535 | – | 2.02% | – |
| MGTX | New | MEIRAGTX HLDGS PLC | $52,712,000 | – | 6,963,277 | – | 1.65% | – |
| LYRA | New | LYRA THERAPEUTICS INC | $51,679,000 | – | 9,146,730 | – | 1.62% | – |
| BLU | New | BELLUS HEALTH INC NEW | $51,136,000 | – | 5,534,169 | – | 1.60% | – |
| RXDX | New | PROMETHEUS BIOSCIENCES INC | $47,490,000 | – | 1,682,242 | – | 1.49% | – |
| ALBO | New | ALBIREO PHARMA INC | $46,872,000 | – | 2,360,139 | – | 1.47% | – |
| New | CINCOR PHARMA INC | $43,692,000 | – | 2,319,117 | – | 1.37% | – | |
| VBIV | New | VBI VACCINES INC CDA | $42,312,000 | – | 52,335,002 | – | 1.32% | – |
| SGEN | New | SEAGEN INC | $39,635,000 | – | 224,000 | – | 1.24% | – |
| VERU | New | VERU INC | $39,550,000 | – | 3,500,000 | – | 1.24% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $39,516,000 | – | 9,903,879 | – | 1.24% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $38,786,000 | – | 397,888 | – | 1.22% | – |
| RAPT | New | RAPT THERAPEUTICS INC | $34,927,000 | – | 1,913,791 | – | 1.09% | – |
| RLAY | New | RELAY THERAPEUTICS INC | $32,546,000 | – | 1,943,097 | – | 1.02% | – |
| LLY | New | LILLY ELI & CO | $32,423,000 | – | 100,000 | – | 1.02% | – |
| New | COHERUS BIOSCIENCES INCnote 1.500% 4/1 | $29,484,000 | – | 4,500,000 | – | 0.92% | – | |
| COGT | New | COGENT BIOSCIENCES INC | $27,863,000 | – | 3,088,972 | – | 0.87% | – |
| CHRS | New | COHERUS BIOSCIENCES INC | $26,393,000 | – | 3,645,471 | – | 0.83% | – |
| MDGL | New | MADRIGAL PHARMACEUTICALS INC | $26,306,000 | – | 367,501 | – | 0.82% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $25,231,000 | – | 172,991 | – | 0.79% | – |
| NAUT | New | NAUTILUS BIOTECHNOLOGY INC | $24,508,000 | – | 9,111,151 | – | 0.77% | – |
| New | PROCEPT BIOROBOTICS CORP | $24,508,000 | – | 749,700 | – | 0.77% | – | |
| ADMA | New | ADMA BIOLOGICS INC | $22,812,000 | – | 11,521,102 | – | 0.71% | – |
| New | NUVALENT INC | $22,442,000 | – | 1,655,007 | – | 0.70% | – | |
| ESTA | New | ESTABLISHMENT LABS HLDGS INC | $22,065,000 | – | 405,759 | – | 0.69% | – |
| ZYME | New | ZYMEWORKS INC | $21,902,000 | – | 4,132,534 | – | 0.69% | – |
| IMTX | New | IMMATICS N.V | $21,775,000 | – | 2,500,000 | – | 0.68% | – |
| INBX | New | INHIBRX INC | $21,731,000 | – | 1,914,592 | – | 0.68% | – |
| New | ARCELLX INC | $20,647,000 | – | 1,141,990 | – | 0.65% | – | |
| HRMY | New | HARMONY BIOSCIENCES HLDGS IN | $20,084,000 | – | 411,804 | – | 0.63% | – |
| ISEE | New | IVERIC BIO INC | $20,086,000 | – | 2,087,956 | – | 0.63% | – |
| TARS | New | TARSUS PHARMACEUTICALS INC | $18,927,000 | – | 1,296,416 | – | 0.59% | – |
| CRY | New | ARTIVION INC | $17,553,000 | – | 929,705 | – | 0.55% | – |
| New | DICE THERAPEUTICS INC | $16,326,000 | – | 1,051,904 | – | 0.51% | – | |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $16,056,000 | – | 1,166,883 | – | 0.50% | – |
| BBIO | New | BRIDGEBIO PHARMA INC | $15,409,000 | – | 1,697,033 | – | 0.48% | – |
| BMRN | New | BIOMARIN PHARMACEUTICAL INC | $14,917,000 | – | 180,000 | – | 0.47% | – |
| OM | New | OUTSET MED INC | $14,841,000 | – | 998,727 | – | 0.46% | – |
| ATHA | New | ATHIRA PHARMA INC | $14,632,000 | – | 4,797,278 | – | 0.46% | – |
| APLS | New | APELLIS PHARMACEUTICALS INC | $14,529,000 | – | 321,300 | – | 0.46% | – |
| RAIN | New | RAIN THERAPEUTICS INC | $13,809,000 | – | 2,483,619 | – | 0.43% | – |
| TVTX | New | TRAVERE THERAPEUTICS INC | $13,813,000 | – | 570,084 | – | 0.43% | – |
| OMIC | New | SINGULAR GENOMICS SYSTEMS IN | $13,509,000 | – | 3,536,274 | – | 0.42% | – |
| TMCI | New | TREACE MED CONCEPTS INC | $13,497,000 | – | 941,192 | – | 0.42% | – |
| VRNA | New | VERONA PHARMA PLCsponsored ads | $12,214,000 | – | 2,915,146 | – | 0.38% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $11,244,000 | – | 971,832 | – | 0.35% | – |
| CCXI | New | CHEMOCENTRYX INC | $10,945,000 | – | 441,680 | – | 0.34% | – |
| CMAX | New | CAREMAX INC | $10,890,000 | – | 3,000,000 | – | 0.34% | – |
| LABP | New | LANDOS BIOPHARMA INC | $10,823,000 | – | 14,869,915 | – | 0.34% | – |
| DAWN | New | DAY ONE BIOPHARMACEUTICALS I | $9,953,000 | – | 556,047 | – | 0.31% | – |
| VRCA | New | VERRICA PHARMACEUTICALS INC | $9,675,000 | – | 5,038,983 | – | 0.30% | – |
| LPTX | New | LEAP THERAPEUTICS INC | $9,144,000 | – | 7,951,448 | – | 0.29% | – |
| CNCE | New | CONCERT PHARMACEUTICALS INC | $9,054,000 | – | 2,150,641 | – | 0.28% | – |
| New | ISOPLEXIS CORP | $8,846,000 | – | 4,095,498 | – | 0.28% | – | |
| KRON | New | KRONOS BIO INC | $8,812,000 | – | 2,421,142 | – | 0.28% | – |
| New | HILLEVAX INC | $8,360,000 | – | 764,907 | – | 0.26% | – | |
| SLDB | New | SOLID BIOSCIENCES INC | $8,257,000 | – | 13,412,552 | – | 0.26% | – |
| PRVA | New | PRIVIA HEALTH GROUP INC | $7,962,000 | – | 273,423 | – | 0.25% | – |
| RVNC | New | REVANCE THERAPEUTICS INC | $7,912,000 | – | 572,514 | – | 0.25% | – |
| MORF | New | MORPHIC HLDG INC | $7,881,000 | – | 363,197 | – | 0.25% | – |
| XBI | New | SPDR SER TRput | $7,427,000 | – | 100,000 | – | 0.23% | – |
| PNT | New | POINT BIOPHARMA GLOBAL INC | $7,314,000 | – | 1,073,995 | – | 0.23% | – |
| New | SOMALOGIC INC | $6,780,000 | – | 1,500,000 | – | 0.21% | – | |
| HCAT | New | HEALTH CATALYST INC | $6,740,000 | – | 465,162 | – | 0.21% | – |
| New | SEMA4 HOLDINGS CORP | $6,300,000 | – | 5,000,000 | – | 0.20% | – | |
| New | ICOSAVAX INC | $5,976,000 | – | 1,042,850 | – | 0.19% | – | |
| CCCC | New | C4 THERAPEUTICS INC | $5,777,000 | – | 766,231 | – | 0.18% | – |
| NUVB | New | NUVATION BIO INC | $5,733,000 | – | 1,769,701 | – | 0.18% | – |
| ATNX | New | ATHENEX INC | $5,540,000 | – | 13,532,467 | – | 0.17% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $4,764,000 | – | 341,239 | – | 0.15% | – |
| NBTX | New | NANOBIOTIXsponsored ads | $4,027,000 | – | 1,059,800 | – | 0.13% | – |
| QTNT | New | QUOTIENT LTD | $3,888,000 | – | 16,200,818 | – | 0.12% | – |
| New | ASTRIA THERAPEUTICS INC | $3,843,000 | – | 1,281,197 | – | 0.12% | – | |
| New | PYXIS ONCOLOGY INC | $3,639,000 | – | 1,528,812 | – | 0.11% | – | |
| MGNX | New | MACROGENICS INC | $3,620,000 | – | 1,227,202 | – | 0.11% | – |
| New | TYRA BIOSCIENCES INC | $3,535,000 | – | 494,403 | – | 0.11% | – | |
| CLOV | New | CLOVER HEALTH INVESTMENTS CO | $3,210,000 | – | 1,500,000 | – | 0.10% | – |
| YMAB | New | Y-MABS THERAPEUTICS INC | $3,208,000 | – | 212,018 | – | 0.10% | – |
| New | SCIENCE 37 HOLDINGS INC | $3,015,000 | – | 1,500,000 | – | 0.09% | – | |
| New | ABSCI CORPORATION | $2,969,000 | – | 894,346 | – | 0.09% | – | |
| New | ENVVENO MEDICAL CORPORATION | $2,954,000 | – | 781,615 | – | 0.09% | – | |
| SAVA | New | CASSAVA SCIENCES INCput | $2,812,000 | – | 100,000 | – | 0.09% | – |
| FUSN | New | FUSION PHARMACEUTICALS INC | $2,621,000 | – | 1,052,445 | – | 0.08% | – |
| New | HYPERFINE INC | $2,530,000 | – | 1,134,388 | – | 0.08% | – | |
| ABOS | New | ACUMEN PHARMACEUTICALS INC | $2,390,000 | – | 508,532 | – | 0.08% | – |
| RLMD | New | RELMADA THERAPEUTICS INC | $2,304,000 | – | 121,350 | – | 0.07% | – |
| New | DARIOHEALTH CORP | $2,013,000 | – | 327,869 | – | 0.06% | – | |
| FULC | New | FULCRUM THERAPEUTICS INC | $1,441,000 | – | 294,118 | – | 0.04% | – |
| New | PEAR THERAPEUTICS INC | $1,386,000 | – | 900,548 | – | 0.04% | – | |
| RACE | New | FERRARI N V | $1,138,000 | – | 6,200 | – | 0.04% | – |
| New | SONENDO INC | $1,115,000 | – | 648,505 | – | 0.04% | – | |
| ZY | New | ZYMERGEN INC | $1,086,000 | – | 883,332 | – | 0.03% | – |
| TARA | New | PROTARA THERAPEUTICS INC | $850,000 | – | 290,051 | – | 0.03% | – |
| New | AGILE THERAPEUTICS INC | $620,000 | – | 532,361 | – | 0.02% | – | |
| MOTS | New | MOTUS GI HLDGS INC | $507,000 | – | 1,800,542 | – | 0.02% | – |
| PRVB | New | PROVENTION BIO INC | $443,000 | – | 110,728 | – | 0.01% | – |
| New | EQRX INC*w exp 12/17/202 | $203,000 | – | 250,000 | – | 0.01% | – | |
| New | NEPTUNE WELLNESS SOLUTIONS I | $81,000 | – | 57,142 | – | 0.00% | – | |
| New | SURROZEN INC | $18,000 | – | 6,017 | – | 0.00% | – | |
| CMAXW | New | CAREMAX INC*w exp 06/08/202 | $43,000 | – | 60,000 | – | 0.00% | – |
| New | SURROZEN INC*w exp 08/01/203 | $32,000 | – | 166,666 | – | 0.00% | – |
Q4 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CMAXW | Exit | CAREMAX INC*w exp 06/08/202 | $0 | – | -60,000 | – | -0.00% | – |
| Exit | SURROZEN INC*w exp 08/01/203 | $0 | – | -166,666 | – | -0.00% | – | |
| Exit | SOMALOGIC INC*w exp 03/01/202 | $0 | – | -110,000 | – | -0.01% | – | |
| PHVS | Exit | PHARVARIS N V | $0 | – | -27,000 | – | -0.01% | – |
| BFLYWS | Exit | BUTTERFLY NETWORK INC*w exp 02/12/202 | $0 | – | -233,333 | – | -0.01% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -139,890 | – | -0.01% | – |
| Exit | ROCKLEY PHOTONICS HOLDINGS L*w exp 08/11/202 | $0 | – | -500,000 | – | -0.02% | – | |
| MOTS | Exit | MOTUS GI HLDGS INC | $0 | – | -1,800,542 | – | -0.02% | – |
| RACE | Exit | FERRARI N V | $0 | – | -6,200 | – | -0.02% | – |
| FREQ | Exit | FREQUENCY THERAPEUTICS INC | $0 | – | -222,222 | – | -0.02% | – |
| Exit | IMAGO BIOSCIENCES INC | $0 | – | -125,000 | – | -0.04% | – | |
| AXSM | Exit | AXSOME THERAPEUTICS INC | $0 | – | -80,420 | – | -0.04% | – |
| TARA | Exit | PROTARA THERAPEUTICS INC | $0 | – | -421,641 | – | -0.04% | – |
| LSAQ | Exit | LIFESCI ACQUISITION II CORP | $0 | – | -300,000 | – | -0.04% | – |
| VYNE | Exit | VYNE THERAPEUTICS INC | $0 | – | -2,330,471 | – | -0.05% | – |
| Exit | SURROZEN INC | $0 | – | -500,000 | – | -0.05% | – | |
| RGNX | Exit | REGENXBIO INC | $0 | – | -89,283 | – | -0.05% | – |
| HSAQ | Exit | HEALTH SCIENCES ACQ CORP 2 | $0 | – | -450,000 | – | -0.06% | – |
| Exit | DARIOHEALTH CORP | $0 | – | -327,869 | – | -0.06% | – | |
| DNAY | Exit | CODEX DNA INC | $0 | – | -425,000 | – | -0.07% | – |
| Exit | DA32 LIFE SCNCE TEC ACQSTN C | $0 | – | -500,000 | – | -0.07% | – | |
| ATEC | Exit | ALPHATEC HLDGS INC | $0 | – | -430,900 | – | -0.08% | – |
| PSTX | Exit | POSEIDA THERAPEUTICS INC | $0 | – | -787,745 | – | -0.08% | – |
| ACHL | Exit | ACHILLES THERAPEUTICS PLCsponsored ads | $0 | – | -755,375 | – | -0.08% | – |
| TSHA | Exit | TAYSHA GENE THERAPIES INC | $0 | – | -320,440 | – | -0.09% | – |
| PRVB | Exit | PROVENTION BIO INC | $0 | – | -948,481 | – | -0.09% | – |
| NEPT | Exit | NEPTUNE WELLNESS SOLUTIONS I | $0 | – | -10,055,521 | – | -0.09% | – |
| SAVA | Exit | CASSAVA SCIENCES INCput | $0 | – | -100,000 | – | -0.09% | – |
| Exit | RAPID MICRO BIOSYSTEMS INC | $0 | – | -350,000 | – | -0.09% | – | |
| CNCE | Exit | CONCERT PHARMACEUTICALS INC | $0 | – | -2,150,641 | – | -0.10% | – |
| PRTA | Exit | PROTHENA CORP PLC | $0 | – | -100,000 | – | -0.10% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -294,118 | – | -0.12% | – |
| Exit | SIGHT SCIENCES INC | $0 | – | -390,000 | – | -0.13% | – | |
| PMVP | Exit | PMV PHARMACEUTICALS INC | $0 | – | -301,714 | – | -0.13% | – |
| CCXI | Exit | CHEMOCENTRYX INC | $0 | – | -550,000 | – | -0.14% | – |
| PNT | Exit | POINT BIOPHARMA GLOBAL INC | $0 | – | -1,242,879 | – | -0.14% | – |
| RACB | Exit | RESEARCH ALLIANCE CORP II | $0 | – | -1,000,000 | – | -0.14% | – |
| FUSN | Exit | FUSION PHARMACEUTICALS INC | $0 | – | -1,254,607 | – | -0.14% | – |
| BLSA | Exit | BCLS ACQUISITION CORP | $0 | – | -1,000,000 | – | -0.14% | – |
| SMIHU | Exit | SUMMIT HEALTHCRE ACQUISTN COunit 06/03/2026 | $0 | – | -1,000,000 | – | -0.15% | – |
| FDMT | Exit | 4D MOLECULAR THERAPEUTICS IN | $0 | – | -375,256 | – | -0.15% | – |
| ONCR | Exit | ONCORUS INC | $0 | – | -1,099,810 | – | -0.15% | – |
| KYMR | Exit | KYMERA THERAPEUTICS INC | $0 | – | -180,000 | – | -0.15% | – |
| ONEM | Exit | 1LIFE HEALTHCARE INC | $0 | – | -532,350 | – | -0.16% | – |
| CLOV | Exit | CLOVER HEALTH INVESTMENTS CO | $0 | – | -1,500,000 | – | -0.16% | – |
| ZY | Exit | ZYMERGEN INC | $0 | – | -883,332 | – | -0.17% | – |
| ACCD | Exit | ACCOLADE INC | $0 | – | -279,774 | – | -0.17% | – |
| ADPT | Exit | ADAPTIVE BIOTECHNOLOGIES COR | $0 | – | -352,804 | – | -0.17% | – |
| NBTX | Exit | NANOBIOTIX SAsponsored ads | $0 | – | -1,059,800 | – | -0.18% | – |
| PODD | Exit | INSULET CORP | $0 | – | -44,522 | – | -0.18% | – |
| CMLTU | Exit | CM LIFE SCIENCES III INCunit 04/30/2028 | $0 | – | -1,250,000 | – | -0.19% | – |
| Exit | NANOSTRING TECHNOLOGIES INCnote 2.625% 3/0 | $0 | – | -1,000,000 | – | -0.19% | – | |
| DAWN | Exit | DAY ONE BIOPHARMACEUTICALS I | $0 | – | -556,047 | – | -0.19% | – |
| VTRS | Exit | VIATRIS INC | $0 | – | -1,004,419 | – | -0.20% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -48,600 | – | -0.20% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -781,236 | – | -0.20% | – |
| GRPH | Exit | GRAPHITE BIO INC | $0 | – | -875,093 | – | -0.21% | – |
| IMCR | Exit | IMMUNOCORE HLDGS PLCads | $0 | – | -400,000 | – | -0.22% | – |
| HCAQ | Exit | HEALTHCOR CATALIO ACQU CORP | $0 | – | -1,500,000 | – | -0.22% | – |
| ADMA | Exit | ADMA BIOLOGICS INC | $0 | – | -13,262,375 | – | -0.22% | – |
| AGRX | Exit | AGILE THERAPEUTICS INC | $0 | – | -15,919,925 | – | -0.22% | – |
| CCXI | Exit | CHEMOCENTRYX INCcall | $0 | – | -923,200 | – | -0.23% | – |
| VRNA | Exit | VERONA PHARMA PLCsponsored ads | $0 | – | -2,888,889 | – | -0.23% | – |
| Exit | NUVALENT INC | $0 | – | -750,000 | – | -0.25% | – | |
| Exit | ABSCI CORPORATION | $0 | – | -1,476,776 | – | -0.25% | – | |
| Exit | TYRA BIOSCIENCES INC | $0 | – | -987,500 | – | -0.25% | – | |
| Exit | ASTRIA THERAPEUTICS INC | $0 | – | -1,959,652 | – | -0.25% | – | |
| NTRA | Exit | NATERA INC | $0 | – | -160,000 | – | -0.26% | – |
| Exit | IMMUNEERING CORP | $0 | – | -681,051 | – | -0.26% | – | |
| Exit | CUE HEALTH INC | $0 | – | -1,580,607 | – | -0.27% | – | |
| HRMY | Exit | HARMONY BIOSCIENCES HLDGS IN | $0 | – | -491,332 | – | -0.27% | – |
| Exit | SEMA4 HOLDINGS CORP | $0 | – | -2,500,000 | – | -0.28% | – | |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -615,000 | – | -0.29% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -393,613 | – | -0.31% | – |
| RNA | Exit | AVIDITY BIOSCIENCES INC | $0 | – | -885,818 | – | -0.32% | – |
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -1,423,000 | – | -0.34% | – |
| BCAB | Exit | BIOATLA INC | $0 | – | -850,026 | – | -0.36% | – |
| Exit | SOMALOGIC INC | $0 | – | -2,050,000 | – | -0.37% | – | |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -141,700 | – | -0.38% | – |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -3,188,750 | – | -0.39% | – |
| TARS | Exit | TARSUS PHARMACEUTICALS INC | $0 | – | -1,296,416 | – | -0.41% | – |
| LYRA | Exit | LYRA THERAPEUTICS INC | $0 | – | -3,222,560 | – | -0.43% | – |
| HCAT | Exit | HEALTH CATALYST INC | $0 | – | -589,004 | – | -0.43% | – |
| NVRO | Exit | NEVRO CORP | $0 | – | -259,972 | – | -0.44% | – |
| NUVB | Exit | NUVATION BIO INC | $0 | – | -3,041,004 | – | -0.44% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -2,022,051 | – | -0.45% | – |
| SLDB | Exit | SOLID BIOSCIENCES INC | $0 | – | -13,412,552 | – | -0.47% | – |
| ATHA | Exit | ATHIRA PHARMA INC | $0 | – | -3,425,916 | – | -0.47% | – |
| IMTX | Exit | IMMATICS N.V | $0 | – | -2,500,000 | – | -0.47% | – |
| CMAX | Exit | CAREMAX INC | $0 | – | -3,385,000 | – | -0.48% | – |
| TMCI | Exit | TREACE MED CONCEPTS INC | $0 | – | -1,235,886 | – | -0.48% | – |
| LPTX | Exit | LEAP THERAPEUTICS INC | $0 | – | -8,476,496 | – | -0.49% | – |
| OMIC | Exit | SINGULAR GENOMICS SYSTEMS IN | $0 | – | -3,073,824 | – | -0.50% | – |
| ESTA | Exit | ESTABLISHMENT LABS HLDGS INC | $0 | – | -505,541 | – | -0.53% | – |
| INBX | Exit | INHIBRX INC | $0 | – | -1,121,490 | – | -0.54% | – |
| DBVT | Exit | DBV TECHNOLOGIES S Asponsored adr | $0 | – | -7,695,505 | – | -0.55% | – |
| QTNT | Exit | QUOTIENT LTD | $0 | – | -16,200,818 | – | -0.55% | – |
| RAIN | Exit | RAIN THERAPEUTICS INC | $0 | – | -2,537,019 | – | -0.55% | – |
| VERU | Exit | VERU INC | $0 | – | -4,451,342 | – | -0.55% | – |
| ATNX | Exit | ATHENEX INC | $0 | – | -13,532,467 | – | -0.59% | – |
| KOD | Exit | KODIAK SCIENCES INC | $0 | – | -461,248 | – | -0.64% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -2,148,060 | – | -0.65% | – |
| VRCA | Exit | VERRICA PHARMACEUTICALS INC | $0 | – | -3,610,412 | – | -0.66% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -483,007 | – | -0.67% | – |
| BEAM | Exit | BEAM THERAPEUTICS INC | $0 | – | -537,635 | – | -0.68% | – |
| TVTX | Exit | TRAVERE THERAPEUTICS INC | $0 | – | -1,965,555 | – | -0.69% | – |
| Exit | COHERUS BIOSCIENCES INCnote 1.500% 4/1 | $0 | – | -4,500,000 | – | -0.72% | – | |
| MORF | Exit | MORPHIC HLDG INC | $0 | – | -887,340 | – | -0.73% | – |
| KRON | Exit | KRONOS BIO INC | $0 | – | -2,421,142 | – | -0.74% | – |
| NAUT | Exit | NAUTILUS BIOTECHNOLOGY INC | $0 | – | -8,911,151 | – | -0.80% | – |
| Exit | ICOSAVAX INC | $0 | – | -1,922,549 | – | -0.83% | – | |
| RLAY | Exit | RELAY THERAPEUTICS INC | $0 | – | -1,943,097 | – | -0.89% | – |
| Exit | PROCEPT BIOROBOTICS CORP | $0 | – | -1,656,990 | – | -0.92% | – | |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -2,310,261 | – | -1.00% | – |
| ALBO | Exit | ALBIREO PHARMA INC | $0 | – | -2,360,139 | – | -1.07% | – |
| CHRS | Exit | COHERUS BIOSCIENCES INC | $0 | – | -4,779,387 | – | -1.12% | – |
| RXDX | Exit | PROMETHEUS BIOSCIENCES INC | $0 | – | -3,314,032 | – | -1.14% | – |
| AVIR | Exit | ATEA PHARMACEUTICALS INC | $0 | – | -2,259,224 | – | -1.15% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS IN | $0 | – | -3,963,517 | – | -1.21% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INC | $0 | – | -9,903,879 | – | -1.26% | – |
| RAPT | Exit | RAPT THERAPEUTICS INC | $0 | – | -2,907,565 | – | -1.31% | – |
| MGTX | Exit | MEIRAGTX HLDGS PLC | $0 | – | -6,948,277 | – | -1.33% | – |
| OM | Exit | OUTSET MED INC | $0 | – | -1,990,633 | – | -1.43% | – |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -2,258,566 | – | -1.47% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -3,679,845 | – | -1.55% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -3,923,741 | – | -1.62% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -4,407,399 | – | -1.63% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -7,471,798 | – | -1.76% | – |
| Exit | NEVRO CORPnote 2.750% 4/0 | $0 | – | -9,000,000 | – | -1.83% | – | |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -5,086,727 | – | -2.18% | – |
| VBIV | Exit | VBI VACCINES INC CDA | $0 | – | -55,042,465 | – | -2.49% | – |
| Exit | COLLEGIUM PHARMACEUTICAL INCnote 2.625% 2/1 | $0 | – | -17,500,000 | – | -2.62% | – | |
| HZNP | Exit | HORIZON THERAPEUTICS PUB L | $0 | – | -1,956,940 | – | -3.11% | – |
| LABP | Exit | LANDOS BIOPHARMA INC | $0 | – | -14,869,915 | – | -3.15% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -26,559,443 | – | -3.68% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -11,489,772 | – | -4.12% | – |
| SWTX | Exit | SPRINGWORKS THERAPEUTICS INC | $0 | – | -4,849,912 | – | -4.47% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INC | $0 | – | -7,756,928 | – | -5.28% | – |
| Exit | TRAVERE THERAPEUTICS INCnote 2.500% 9/1 | $0 | – | -45,000,000 | – | -6.61% | – | |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -3,387,745 | – | -8.71% | – |
Q3 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MRTX | Sell | MIRATI THERAPEUTICS INC | $599,326,000 | -41.8% | 3,387,745 | -46.8% | 8.71% | +30.2% |
| Sell | TRAVERE THERAPEUTICS INCnote 2.500% 9/1 | $454,824,000 | -40.8% | 45,000,000 | -50.0% | 6.61% | +32.3% | |
| BBIO | Sell | BRIDGEBIO PHARMA INC | $363,567,000 | -61.6% | 7,756,928 | -50.0% | 5.28% | -14.0% |
| SWTX | Sell | SPRINGWORKS THERAPEUTICS INC | $307,678,000 | -61.5% | 4,849,912 | -50.0% | 4.47% | -13.9% |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $283,337,000 | -50.3% | 11,489,772 | -47.6% | 4.12% | +11.1% |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $253,643,000 | -43.1% | 26,559,443 | -42.6% | 3.68% | +27.3% |
| LABP | Sell | LANDOS BIOPHARMA INC | $217,101,000 | -36.8% | 14,869,915 | -50.0% | 3.15% | +41.4% |
| HZNP | Sell | HORIZON THERAPEUTICS PUB L | $214,363,000 | -42.3% | 1,956,940 | -50.7% | 3.11% | +29.0% |
| Sell | COLLEGIUM PHARMACEUTICAL INCnote 2.625% 2/1 | $180,250,000 | -52.5% | 17,500,000 | -50.0% | 2.62% | +6.2% | |
| VBIV | Sell | VBI VACCINES INC CDA | $171,182,000 | -53.6% | 55,042,465 | -50.0% | 2.49% | +3.8% |
| CERE | Sell | CEREVEL THERAPEUTICS HLDNG I | $150,058,000 | -36.9% | 5,086,727 | -45.2% | 2.18% | +41.1% |
| Sell | NEVRO CORPnote 2.750% 4/0 | $126,234,000 | -59.6% | 9,000,000 | -50.0% | 1.83% | -9.7% | |
| ISEE | Sell | IVERIC BIO INC | $121,342,000 | +109.7% | 7,471,798 | -18.5% | 1.76% | +368.9% |
| GBT | Sell | GLOBAL BLOOD THERAPEUTICS IN | $112,300,000 | -61.4% | 4,407,399 | -46.9% | 1.63% | -13.7% |
| NVTA | Sell | INVITAE CORP | $111,551,000 | -65.7% | 3,923,741 | -59.3% | 1.62% | -23.3% |
| ZYME | Sell | ZYMEWORKS INC | $106,863,000 | -64.2% | 3,679,845 | -57.3% | 1.55% | -20.0% |
| CCCC | Sell | C4 THERAPEUTICS INC | $100,913,000 | -41.0% | 2,258,566 | -50.0% | 1.47% | +32.1% |
| OM | Sell | OUTSET MED INC | $98,417,000 | -58.8% | 1,990,633 | -58.3% | 1.43% | -7.7% |
| MGTX | Sell | MEIRAGTX HLDGS PLC | $91,578,000 | -57.5% | 6,948,277 | -50.0% | 1.33% | -4.9% |
| RAPT | Sell | RAPT THERAPEUTICS INC | $90,280,000 | -42.6% | 2,907,565 | -41.3% | 1.31% | +28.3% |
| ALDX | Sell | ALDEYRA THERAPEUTICS INC | $86,956,000 | -61.3% | 9,903,879 | -50.0% | 1.26% | -13.4% |
| CRNX | Sell | CRINETICS PHARMACEUTICALS IN | $83,432,000 | -44.2% | 3,963,517 | -50.0% | 1.21% | +24.9% |
| AVIR | Sell | ATEA PHARMACEUTICALS INC | $79,208,000 | -18.4% | 2,259,224 | -50.0% | 1.15% | +82.7% |
| RXDX | Sell | PROMETHEUS BIOSCIENCES INC | $78,576,000 | -51.7% | 3,314,032 | -50.0% | 1.14% | +7.9% |
| CHRS | Sell | COHERUS BIOSCIENCES INC | $76,805,000 | -40.9% | 4,779,387 | -49.1% | 1.12% | +32.2% |
| ALBO | Sell | ALBIREO PHARMA INC | $73,636,000 | -55.7% | 2,360,139 | -50.0% | 1.07% | -0.8% |
| RCKT | Sell | ROCKET PHARMACEUTICALS INC | $69,054,000 | -71.7% | 2,310,261 | -58.0% | 1.00% | -36.6% |
| New | PROCEPT BIOROBOTICS CORP | $63,214,000 | – | 1,656,990 | – | 0.92% | – | |
| RLAY | Sell | RELAY THERAPEUTICS INC | $61,266,000 | -58.5% | 1,943,097 | -51.9% | 0.89% | -7.2% |
| New | ICOSAVAX INC | $56,888,000 | – | 1,922,549 | – | 0.83% | – | |
| NAUT | Sell | NAUTILUS BIOTECHNOLOGY INC | $54,714,000 | -69.6% | 8,911,151 | -50.0% | 0.80% | -32.0% |
| KRON | Sell | KRONOS BIO INC | $50,747,000 | -58.1% | 2,421,142 | -52.1% | 0.74% | -6.2% |
| MORF | Sell | MORPHIC HLDG INC | $50,259,000 | -53.3% | 887,340 | -52.7% | 0.73% | +4.4% |
| Sell | COHERUS BIOSCIENCES INCnote 1.500% 4/1 | $49,365,000 | -46.4% | 4,500,000 | -50.0% | 0.72% | +19.9% | |
| TVTX | Sell | TRAVERE THERAPEUTICS INC | $47,665,000 | -11.5% | 1,965,555 | -46.7% | 0.69% | +97.7% |
| BEAM | Sell | BEAM THERAPEUTICS INC | $46,780,000 | -66.2% | 537,635 | -50.0% | 0.68% | -24.4% |
| NBIX | Sell | NEUROCRINE BIOSCIENCES INC | $46,325,000 | -70.7% | 483,007 | -70.3% | 0.67% | -34.4% |
| VRCA | Sell | VERRICA PHARMACEUTICALS INC | $45,130,000 | -44.7% | 3,610,412 | -50.0% | 0.66% | +23.8% |
| MGNX | Sell | MACROGENICS INC | $44,980,000 | -61.0% | 2,148,060 | -50.0% | 0.65% | -12.8% |
| KOD | Sell | KODIAK SCIENCES INC | $44,271,000 | -16.8% | 461,248 | -19.4% | 0.64% | +85.8% |
| ATNX | Sell | ATHENEX INC | $40,733,000 | -67.4% | 13,532,467 | -50.0% | 0.59% | -27.1% |
| VERU | Sell | VERU INC | $37,970,000 | -47.1% | 4,451,342 | -50.0% | 0.55% | +18.2% |
| QTNT | Sell | QUOTIENT LTD | $37,910,000 | -67.9% | 16,200,818 | -50.0% | 0.55% | -28.1% |
| RAIN | Sell | RAIN THERAPEUTICS INC | $37,954,000 | -51.9% | 2,537,019 | -50.0% | 0.55% | +7.6% |
| DBVT | Sell | DBV TECHNOLOGIES S Asponsored adr | $37,708,000 | -55.1% | 7,695,505 | -50.0% | 0.55% | +0.4% |
| INBX | Sell | INHIBRX INC | $37,357,000 | -25.2% | 1,121,490 | -38.2% | 0.54% | +67.6% |
| ESTA | Sell | ESTABLISHMENT LABS HLDGS INC | $36,186,000 | -70.4% | 505,541 | -63.9% | 0.53% | -33.8% |
| OMIC | Sell | SINGULAR GENOMICS SYSTEMS IN | $34,396,000 | -79.7% | 3,073,824 | -50.1% | 0.50% | -54.5% |
| LPTX | Sell | LEAP THERAPEUTICS INC | $33,990,000 | +22.3% | 8,476,496 | -50.0% | 0.49% | +172.9% |
| TMCI | Sell | TREACE MED CONCEPTS INC | $33,245,000 | -57.0% | 1,235,886 | -50.0% | 0.48% | -3.8% |
| CMAX | Sell | CAREMAX INC | $32,699,000 | -61.8% | 3,385,000 | -49.0% | 0.48% | -14.6% |
| IMTX | Sell | IMMATICS N.V | $32,500,000 | -44.0% | 2,500,000 | -50.0% | 0.47% | +25.2% |
| ATHA | Sell | ATHIRA PHARMA INC | $32,135,000 | -54.2% | 3,425,916 | -50.0% | 0.47% | +2.4% |
| SLDB | Sell | SOLID BIOSCIENCES INC | $32,056,000 | -67.3% | 13,412,552 | -50.0% | 0.47% | -27.0% |
| XENE | Sell | XENON PHARMACEUTICALS INC | $30,897,000 | -50.6% | 2,022,051 | -39.8% | 0.45% | +10.6% |
| NVRO | Sell | NEVRO CORP | $30,256,000 | -88.9% | 259,972 | -84.1% | 0.44% | -75.1% |
| NUVB | Sell | NUVATION BIO INC | $30,228,000 | -46.6% | 3,041,004 | -50.0% | 0.44% | +19.3% |
| HCAT | Sell | HEALTH CATALYST INC | $29,456,000 | -53.1% | 589,004 | -48.0% | 0.43% | +4.9% |
| LYRA | Sell | LYRA THERAPEUTICS INC | $29,403,000 | -43.2% | 3,222,560 | -50.0% | 0.43% | +27.1% |
| TARS | Sell | TARSUS PHARMACEUTICALS INC | $27,937,000 | -62.8% | 1,296,416 | -50.0% | 0.41% | -16.8% |
| COGT | Sell | COGENT BIOSCIENCES INC | $26,817,000 | -48.2% | 3,188,750 | -50.0% | 0.39% | +16.1% |
| UTHR | Sell | UNITED THERAPEUTICS CORP DEL | $26,155,000 | -88.2% | 141,700 | -88.5% | 0.38% | -73.6% |
| New | SOMALOGIC INC | $25,400,000 | – | 2,050,000 | – | 0.37% | – | |
| BCAB | Sell | BIOATLA INC | $25,025,000 | -56.9% | 850,026 | -38.0% | 0.36% | -3.4% |
| VRDN | Sell | VIRIDIAN THERAPEUTICS INC | $23,408,000 | -19.5% | 1,423,000 | -10.4% | 0.34% | +79.9% |
| RNA | Sell | AVIDITY BIOSCIENCES INC | $21,818,000 | -59.1% | 885,818 | -59.0% | 0.32% | -8.4% |
| CLDX | Sell | CELLDEX THERAPEUTICS INC NEW | $21,251,000 | -57.2% | 393,613 | -73.5% | 0.31% | -4.3% |
| APLS | Sell | APELLIS PHARMACEUTICALS INC | $20,270,000 | -75.7% | 615,000 | -53.5% | 0.29% | -45.9% |
| New | SEMA4 HOLDINGS CORP | $18,975,000 | – | 2,500,000 | – | 0.28% | – | |
| HRMY | Sell | HARMONY BIOSCIENCES HLDGS IN | $18,833,000 | -32.1% | 491,332 | -50.0% | 0.27% | +52.2% |
| New | CUE HEALTH INC | $18,667,000 | – | 1,580,607 | – | 0.27% | – | |
| New | IMMUNEERING CORP | $18,082,000 | – | 681,051 | – | 0.26% | – | |
| NTRA | New | NATERA INC | $17,830,000 | – | 160,000 | – | 0.26% | – |
| New | ASTRIA THERAPEUTICS INC | $17,323,000 | – | 1,959,652 | – | 0.25% | – | |
| New | TYRA BIOSCIENCES INC | $17,370,000 | – | 987,500 | – | 0.25% | – | |
| New | ABSCI CORPORATION | $17,175,000 | – | 1,476,776 | – | 0.25% | – | |
| New | NUVALENT INC | $16,913,000 | – | 750,000 | – | 0.25% | – | |
| VRNA | Sell | VERONA PHARMA PLCsponsored ads | $15,831,000 | -58.1% | 2,888,889 | -50.0% | 0.23% | -6.1% |
| CCXI | New | CHEMOCENTRYX INCcall | $15,786,000 | – | 923,200 | – | 0.23% | – |
| AGRX | Sell | AGILE THERAPEUTICS INC | $15,301,000 | -63.9% | 15,919,925 | -50.0% | 0.22% | -19.3% |
| ADMA | Sell | ADMA BIOLOGICS INC | $14,986,000 | -71.8% | 13,262,375 | -60.0% | 0.22% | -36.8% |
| HCAQ | Sell | HEALTHCOR CATALIO ACQU CORP | $14,850,000 | -49.7% | 1,500,000 | -50.0% | 0.22% | +12.5% |
| IMCR | Sell | IMMUNOCORE HLDGS PLCads | $14,828,000 | -52.5% | 400,000 | -50.0% | 0.22% | +5.9% |
| GRPH | Sell | GRAPHITE BIO INC | $14,343,000 | -73.3% | 875,093 | -50.0% | 0.21% | -40.4% |
| ACRS | Sell | ACLARIS THERAPEUTICS INC | $14,062,000 | -52.9% | 781,236 | -54.0% | 0.20% | +5.2% |
| BIIB | New | BIOGEN INC | $13,753,000 | – | 48,600 | – | 0.20% | – |
| VTRS | Sell | VIATRIS INC | $13,610,000 | -52.6% | 1,004,419 | -50.0% | 0.20% | +6.5% |
| DAWN | Sell | DAY ONE BIOPHARMACEUTICALS I | $13,195,000 | -61.7% | 556,047 | -63.2% | 0.19% | -14.3% |
| CMLTU | Sell | CM LIFE SCIENCES III INCunit 04/30/2028 | $12,813,000 | -53.2% | 1,250,000 | -50.0% | 0.19% | +4.5% |
| Sell | NANOSTRING TECHNOLOGIES INCnote 2.625% 3/0 | $12,799,000 | -60.5% | 1,000,000 | -50.0% | 0.19% | -11.4% | |
| PODD | New | INSULET CORP | $12,654,000 | – | 44,522 | – | 0.18% | – |
| NBTX | Sell | NANOBIOTIX SAsponsored ads | $12,039,000 | -58.8% | 1,059,800 | -50.0% | 0.18% | -7.9% |
| ADPT | Sell | ADAPTIVE BIOTECHNOLOGIES COR | $11,992,000 | -58.4% | 352,804 | -50.0% | 0.17% | -7.0% |
| ACCD | Sell | ACCOLADE INC | $11,798,000 | -55.8% | 279,774 | -43.1% | 0.17% | -1.2% |
| ZY | Sell | ZYMERGEN INC | $11,633,000 | -91.1% | 883,332 | -73.0% | 0.17% | -80.1% |
| CLOV | Sell | CLOVER HEALTH INVESTMENTS CO | $11,085,000 | -72.3% | 1,500,000 | -50.0% | 0.16% | -38.1% |
| ONEM | Sell | 1LIFE HEALTHCARE INC | $10,780,000 | -68.4% | 532,350 | -48.4% | 0.16% | -29.3% |
| KYMR | New | KYMERA THERAPEUTICS INC | $10,573,000 | – | 180,000 | – | 0.15% | – |
| ONCR | Sell | ONCORUS INC | $10,272,000 | -74.6% | 1,099,810 | -62.4% | 0.15% | -43.1% |
| FDMT | Sell | 4D MOLECULAR THERAPEUTICS IN | $10,121,000 | -44.0% | 375,256 | -50.0% | 0.15% | +25.6% |
| SMIHU | Sell | SUMMIT HEALTHCRE ACQUISTN COunit 06/03/2026 | $10,050,000 | -49.8% | 1,000,000 | -50.0% | 0.15% | +12.3% |
| BLSA | Sell | BCLS ACQUISITION CORP | $9,960,000 | -52.7% | 1,000,000 | -50.0% | 0.14% | +5.8% |
| FUSN | Sell | FUSION PHARMACEUTICALS INC | $9,936,000 | -65.4% | 1,254,607 | -64.7% | 0.14% | -22.6% |
| RACB | Sell | RESEARCH ALLIANCE CORP II | $9,850,000 | -51.4% | 1,000,000 | -50.0% | 0.14% | +8.3% |
| PNT | New | POINT BIOPHARMA GLOBAL INC | $9,557,000 | – | 1,242,879 | – | 0.14% | – |
| CCXI | New | CHEMOCENTRYX INC | $9,405,000 | – | 550,000 | – | 0.14% | – |
| PMVP | Sell | PMV PHARMACEUTICALS INC | $8,991,000 | -82.4% | 301,714 | -79.8% | 0.13% | -60.4% |
| New | SIGHT SCIENCES INC | $8,853,000 | – | 390,000 | – | 0.13% | – | |
| FULC | Sell | FULCRUM THERAPEUTICS INC | $8,297,000 | +34.6% | 294,118 | -50.0% | 0.12% | +202.5% |
| PRTA | Sell | PROTHENA CORP PLC | $7,123,000 | -30.7% | 100,000 | -50.0% | 0.10% | +53.7% |
| CNCE | Sell | CONCERT PHARMACEUTICALS INC | $7,033,000 | -61.3% | 2,150,641 | -50.0% | 0.10% | -13.6% |
| New | RAPID MICRO BIOSYSTEMS INC | $6,465,000 | – | 350,000 | – | 0.09% | – | |
| SAVA | New | CASSAVA SCIENCES INCput | $6,208,000 | – | 100,000 | – | 0.09% | – |
| NEPT | Sell | NEPTUNE WELLNESS SOLUTIONS I | $6,080,000 | -79.8% | 10,055,521 | -60.9% | 0.09% | -54.9% |
| PRVB | Sell | PROVENTION BIO INC | $6,070,000 | -62.0% | 948,481 | -50.0% | 0.09% | -15.4% |
| TSHA | Sell | TAYSHA GENE THERAPIES INC | $5,967,000 | -56.1% | 320,440 | -50.0% | 0.09% | -1.1% |
| ACHL | Sell | ACHILLES THERAPEUTICS PLCsponsored ads | $5,884,000 | -60.2% | 755,375 | -50.0% | 0.08% | -11.5% |
| PSTX | Sell | POSEIDA THERAPEUTICS INC | $5,743,000 | -63.6% | 787,745 | -50.0% | 0.08% | -19.4% |
| ATEC | Sell | ALPHATEC HLDGS INC | $5,252,000 | -90.5% | 430,900 | -88.0% | 0.08% | -78.8% |
| New | DA32 LIFE SCNCE TEC ACQSTN C | $4,915,000 | – | 500,000 | – | 0.07% | – | |
| DNAY | Sell | CODEX DNA INC | $4,730,000 | -74.7% | 425,000 | -50.0% | 0.07% | -43.0% |
| HSAQ | Sell | HEALTH SCIENCES ACQ CORP 2 | $4,451,000 | -51.5% | 450,000 | -50.0% | 0.06% | +8.3% |
| Sell | DARIOHEALTH CORP | $4,475,000 | -68.0% | 327,869 | -50.0% | 0.06% | -28.6% | |
| RGNX | Sell | REGENXBIO INC | $3,743,000 | -46.1% | 89,283 | -50.0% | 0.05% | +20.0% |
| New | SURROZEN INC | $3,540,000 | – | 500,000 | – | 0.05% | – | |
| VYNE | Sell | VYNE THERAPEUTICS INC | $3,239,000 | -92.0% | 2,330,471 | -79.8% | 0.05% | -82.1% |
| LSAQ | Sell | LIFESCI ACQUISITION II CORP | $2,940,000 | -51.0% | 300,000 | -50.0% | 0.04% | +10.3% |
| TARA | Sell | PROTARA THERAPEUTICS INC | $2,918,000 | -64.5% | 421,641 | -50.0% | 0.04% | -20.8% |
| AXSM | Sell | AXSOME THERAPEUTICS INC | $2,651,000 | -96.5% | 80,420 | -92.7% | 0.04% | -92.0% |
| New | IMAGO BIOSCIENCES INC | $2,504,000 | – | 125,000 | – | 0.04% | – | |
| FREQ | Sell | FREQUENCY THERAPEUTICS INC | $1,569,000 | -64.6% | 222,222 | -50.0% | 0.02% | -20.7% |
| RACE | Sell | FERRARI N V | $1,297,000 | -49.3% | 6,200 | -50.0% | 0.02% | +11.8% |
| MOTS | Sell | MOTUS GI HLDGS INC | $1,242,000 | -66.8% | 1,800,542 | -50.0% | 0.02% | -25.0% |
| New | ROCKLEY PHOTONICS HOLDINGS L*w exp 08/11/202 | $1,195,000 | – | 500,000 | – | 0.02% | – | |
| EIGR | Sell | EIGER BIOPHARMACEUTICALS INC | $934,000 | -60.8% | 139,890 | -50.0% | 0.01% | -6.7% |
| BFLYWS | Sell | BUTTERFLY NETWORK INC*w exp 02/12/202 | $642,000 | -71.5% | 233,333 | -50.0% | 0.01% | -40.0% |
| PHVS | Sell | PHARVARIS N V | $479,000 | -52.4% | 27,000 | -50.0% | 0.01% | 0.0% |
| New | SOMALOGIC INC*w exp 03/01/202 | $380,000 | – | 110,000 | – | 0.01% | – | |
| New | SURROZEN INC*w exp 08/01/203 | $190,000 | – | 166,666 | – | 0.00% | – | |
| CMAXW | Sell | CAREMAX INC*w exp 06/08/202 | $170,000 | -70.0% | 60,000 | -50.0% | 0.00% | -50.0% |
| RAPT | Exit | RAPT THERAPEUTICS INCput | $0 | – | -90,000 | – | -0.00% | – |
| TCRR | Exit | TCR2 THERAPEUTICS INC | $0 | – | -61,506 | – | -0.01% | – |
| TKNO | Exit | ALPHA TEKNOVA INC | $0 | – | -60,000 | – | -0.01% | – |
| PLXP | Exit | PLX PHARMA INC | $0 | – | -114,918 | – | -0.01% | – |
| SCPEWS | Exit | SC HEALTH CORP*w exp 99/99/999 | $0 | – | -1,000,000 | – | -0.01% | – |
| SGTX | Exit | SIGILON THERAPEUTICS INC | $0 | – | -250,000 | – | -0.02% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -133,310 | – | -0.02% | – |
| CEREW | Exit | CEREVEL THERAPEUTICS HLDNG I*w exp 06/09/202 | $0 | – | -266,132 | – | -0.02% | – |
| GRTX | Exit | GALERA THERAPEUTICS INC | $0 | – | -509,328 | – | -0.03% | – |
| CMLF | Exit | CM LIFE SCIENCES INC | $0 | – | -454,000 | – | -0.04% | – |
| AMWL | Exit | AMERICAN WELL CORPcl a | $0 | – | -580,000 | – | -0.05% | – |
| MRUS | Exit | MERUS NV | $0 | – | -350,000 | – | -0.05% | – |
| LGVU | Exit | LONGVIEW ACQUISITION CORP IIunit 99/99/9999 | $0 | – | -1,000,000 | – | -0.06% | – |
| CHFWU | Exit | CONSONANCE HFW ACQUISITION Cunit 99/99/9999 | $0 | – | -1,000,000 | – | -0.07% | – |
| MREO | Exit | MEREO BIOPHARMA GROUP PLCads | $0 | – | -3,392,136 | – | -0.07% | – |
| BCTG | Exit | BCTG ACQUISITION CORP | $0 | – | -1,000,000 | – | -0.07% | – |
| AKYA | Exit | AKOYA BIOSCIENCES INC | $0 | – | -600,000 | – | -0.08% | – |
| PRVA | Exit | PRIVIA HEALTH GROUP INC | $0 | – | -270,000 | – | -0.08% | – |
| SILK | Exit | SILK RD MED INC | $0 | – | -294,266 | – | -0.09% | – |
| RACA | Exit | THERAPEUTICS ACQUISITION COR | $0 | – | -1,500,000 | – | -0.10% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -3,281,914 | – | -0.14% | – |
| CVRX | Exit | CVRX INC | $0 | – | -880,000 | – | -0.16% | – |
| Exit | CATABASIS PHARMACEUTICALS IN | $0 | – | -15,374,370 | – | -0.21% | – | |
| TDOC | Exit | TELADOC HEALTH INCcall | $0 | – | -200,000 | – | -0.22% | – |
| CMIIU | Exit | CM LIFE SCIENCES II INCunit 02/25/2028 | $0 | – | -2,500,000 | – | -0.22% | – |
| STOK | Exit | STOKE THERAPEUTICS INC | $0 | – | -1,343,956 | – | -0.29% | – |
| FBRX | Exit | FORTE BIOSCIENCES INC | $0 | – | -1,370,000 | – | -0.30% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -1,956,554 | – | -0.30% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS IN | $0 | – | -630,282 | – | -0.34% | – |
| RGEN | Exit | REPLIGEN CORP | $0 | – | -265,000 | – | -0.34% | – |
| XLRN | Exit | ACCELERON PHARMA INC | $0 | – | -453,520 | – | -0.37% | – |
| NARI | Exit | INARI MED INC | $0 | – | -620,874 | – | -0.38% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -467,046 | – | -0.38% | – |
| DRNA | Exit | DICERNA PHARMACEUTICALS INC | $0 | – | -1,600,000 | – | -0.39% | – |
| MDT | Exit | MEDTRONIC PLC | $0 | – | -900,000 | – | -0.73% | – |
| KDMN | Exit | KADMON HLDGS INC | $0 | – | -31,422,668 | – | -0.79% | – |
Q2 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MRTX | New | MIRATI THERAPEUTICS INC | $1,029,236,000 | – | 6,371,796 | – | 6.68% | – |
| BBIO | New | BRIDGEBIO PHARMA INC | $945,724,000 | – | 15,513,856 | – | 6.14% | – |
| SWTX | New | SPRINGWORKS THERAPEUTICS INC | $799,362,000 | – | 9,699,824 | – | 5.19% | – |
| New | RETROPHIN INCnote 2.500% 9/1 | $768,844,000 | – | 90,000,000 | – | 4.99% | – | |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $570,346,000 | – | 21,919,544 | – | 3.70% | – |
| FOLD | New | AMICUS THERAPEUTICS INC | $445,780,000 | – | 46,242,658 | – | 2.90% | – |
| New | COLLEGIUM PHARMACEUTICAL INCnote 2.625% 2/1 | $379,446,000 | – | 35,000,000 | – | 2.46% | – | |
| HZNP | New | HORIZON THERAPEUTICS PUB L | $371,750,000 | – | 3,970,004 | – | 2.41% | – |
| VBIV | New | VBI VACCINES INC CDA | $368,784,000 | – | 110,084,930 | – | 2.40% | – |
| LABP | New | LANDOS BIOPHARMA INC | $343,494,000 | – | 29,739,830 | – | 2.23% | – |
| NVTA | New | INVITAE CORP | $325,076,000 | – | 9,637,602 | – | 2.11% | – |
| New | NEVRO CORPnote 2.750% 4/0 | $312,552,000 | – | 18,000,000 | – | 2.03% | – | |
| ZYME | New | ZYMEWORKS INC | $298,722,000 | – | 8,611,200 | – | 1.94% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $290,854,000 | – | 8,305,378 | – | 1.89% | – |
| NVRO | New | NEVRO CORP | $271,484,000 | – | 1,637,520 | – | 1.76% | – |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $243,736,000 | – | 5,503,206 | – | 1.58% | – |
| OM | New | OUTSET MED INC | $238,658,000 | – | 4,775,070 | – | 1.55% | – |
| CERE | New | CEREVEL THERAPEUTICS HLDNG I | $237,912,000 | – | 9,286,190 | – | 1.54% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $224,422,000 | – | 19,807,758 | – | 1.46% | – |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $221,320,000 | – | 1,233,604 | – | 1.44% | – |
| MGTX | New | MEIRAGTX HLDGS PLC | $215,396,000 | – | 13,896,554 | – | 1.40% | – |
| NAUT | New | NAUTILUS BIOTECHNOLOGY INC | $180,004,000 | – | 17,822,302 | – | 1.17% | – |
| CCCC | New | C4 THERAPEUTICS INC | $170,928,000 | – | 4,517,132 | – | 1.11% | – |
| OMIC | New | SINGULAR GENOMICS SYSTEMS IN | $169,434,000 | – | 6,165,740 | – | 1.10% | – |
| ALBO | New | ALBIREO PHARMA INC | $166,060,000 | – | 4,720,278 | – | 1.08% | – |
| RXDX | New | PROMETHEUS BIOSCIENCES INC | $162,786,000 | – | 6,628,064 | – | 1.06% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $158,014,000 | – | 1,623,664 | – | 1.03% | – |
| RAPT | New | RAPT THERAPEUTICS INC | $157,402,000 | – | 4,951,320 | – | 1.02% | – |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $149,424,000 | – | 7,927,034 | – | 0.97% | – |
| RLAY | New | RELAY THERAPEUTICS INC | $147,684,000 | – | 4,036,194 | – | 0.96% | – |
| BEAM | New | BEAM THERAPEUTICS INC | $138,398,000 | – | 1,075,270 | – | 0.90% | – |
| ZY | New | ZYMERGEN INC | $130,698,000 | – | 3,266,664 | – | 0.85% | – |
| CHRS | New | COHERUS BIOSCIENCES INC | $129,936,000 | – | 9,395,224 | – | 0.84% | – |
| ATNX | New | ATHENEX INC | $125,040,000 | – | 27,064,934 | – | 0.81% | – |
| ESTA | New | ESTABLISHMENT LABS HLDGS INC | $122,348,000 | – | 1,400,816 | – | 0.80% | – |
| KDMN | New | KADMON HLDGS INC | $121,606,000 | – | 31,422,668 | – | 0.79% | – |
| KRON | New | KRONOS BIO INC | $121,094,000 | – | 5,056,104 | – | 0.79% | – |
| QTNT | New | QUOTIENT LTD | $117,942,000 | – | 32,401,636 | – | 0.77% | – |
| MGNX | New | MACROGENICS INC | $115,394,000 | – | 4,296,120 | – | 0.75% | – |
| MDT | New | MEDTRONIC PLC | $111,716,000 | – | 900,000 | – | 0.73% | – |
| MORF | New | MORPHIC HLDG INC | $107,680,000 | – | 1,876,280 | – | 0.70% | – |
| SLDB | New | SOLID BIOSCIENCES INC | $98,180,000 | – | 26,825,104 | – | 0.64% | – |
| AVIR | New | ATEA PHARMACEUTICALS INC | $97,056,000 | – | 4,518,448 | – | 0.63% | – |
| New | COHERUS BIOSCIENCES INCnote 1.500% 4/1 | $92,106,000 | – | 9,000,000 | – | 0.60% | – | |
| CMAX | New | CAREMAX INC | $85,656,000 | – | 6,640,000 | – | 0.56% | – |
| DBVT | New | DBV TECHNOLOGIES S Asponsored adr | $84,034,000 | – | 15,391,010 | – | 0.55% | – |
| APLS | New | APELLIS PHARMACEUTICALS INC | $83,570,000 | – | 1,322,324 | – | 0.54% | – |
| VRCA | New | VERRICA PHARMACEUTICALS INC | $81,596,000 | – | 7,220,824 | – | 0.53% | – |
| RAIN | New | RAIN THERAPEUTICS INC | $78,850,000 | – | 5,074,038 | – | 0.51% | – |
| TMCI | New | TREACE MED CONCEPTS INC | $77,268,000 | – | 2,471,772 | – | 0.50% | – |
| TARS | New | TARSUS PHARMACEUTICALS INC | $75,140,000 | – | 2,592,832 | – | 0.49% | – |
| AXSM | New | AXSOME THERAPEUTICS INC | $74,734,000 | – | 1,107,816 | – | 0.48% | – |
| VERU | New | VERU INC | $71,844,000 | – | 8,902,684 | – | 0.47% | – |
| ATHA | New | ATHIRA PHARMA INC | $70,162,000 | – | 6,851,832 | – | 0.46% | – |
| HCAT | New | HEALTH CATALYST INC | $62,846,000 | – | 1,132,168 | – | 0.41% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $62,524,000 | – | 3,357,946 | – | 0.41% | – |
| DRNA | New | DICERNA PHARMACEUTICALS INC | $59,712,000 | – | 1,600,000 | – | 0.39% | – |
| EXAS | New | EXACT SCIENCES CORP | $58,058,000 | – | 467,046 | – | 0.38% | – |
| BCAB | New | BIOATLA INC | $58,104,000 | – | 1,371,038 | – | 0.38% | – |
| IMTX | New | IMMATICS N.V | $58,050,000 | – | 5,000,000 | – | 0.38% | – |
| NARI | New | INARI MED INC | $57,916,000 | – | 620,874 | – | 0.38% | – |
| ISEE | New | IVERIC BIO INC | $57,870,000 | – | 9,171,024 | – | 0.38% | – |
| XLRN | New | ACCELERON PHARMA INC | $56,912,000 | – | 453,520 | – | 0.37% | – |
| NUVB | New | NUVATION BIO INC | $56,624,000 | – | 6,082,008 | – | 0.37% | – |
| ATEC | New | ALPHATEC HLDGS INC | $55,158,000 | – | 3,600,360 | – | 0.36% | – |
| TVTX | New | TRAVERE THERAPEUTICS INC | $53,854,000 | – | 3,691,110 | – | 0.35% | – |
| GRPH | New | GRAPHITE BIO INC | $53,784,000 | – | 1,750,186 | – | 0.35% | – |
| KOD | New | KODIAK SCIENCES INC | $53,204,000 | – | 572,082 | – | 0.35% | – |
| RNA | New | AVIDITY BIOSCIENCES INC | $53,326,000 | – | 2,158,056 | – | 0.35% | – |
| ADMA | New | ADMA BIOLOGICS INC | $53,072,000 | – | 33,169,604 | – | 0.34% | – |
| RGEN | New | REPLIGEN CORP | $52,900,000 | – | 265,000 | – | 0.34% | – |
| ARWR | New | ARROWHEAD PHARMACEUTICALS IN | $52,200,000 | – | 630,282 | – | 0.34% | – |
| COGT | New | COGENT BIOSCIENCES INC | $51,722,000 | – | 6,377,500 | – | 0.34% | – |
| LYRA | New | LYRA THERAPEUTICS INC | $51,754,000 | – | 6,445,120 | – | 0.34% | – |
| PMVP | New | PMV PHARMACEUTICALS INC | $51,004,000 | – | 1,493,114 | – | 0.33% | – |
| INBX | New | INHIBRX INC | $49,926,000 | – | 1,814,180 | – | 0.32% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $49,672,000 | – | 1,485,398 | – | 0.32% | – |
| COLL | New | COLLEGIUM PHARMACEUTICAL INC | $46,252,000 | – | 1,956,554 | – | 0.30% | – |
| FBRX | New | FORTE BIOSCIENCES INC | $46,060,000 | – | 1,370,000 | – | 0.30% | – |
| STOK | New | STOKE THERAPEUTICS INC | $45,238,000 | – | 1,343,956 | – | 0.29% | – |
| AGRX | New | AGILE THERAPEUTICS INC | $42,348,000 | – | 31,839,850 | – | 0.28% | – |
| VYNE | New | VYNE THERAPEUTICS INC | $40,534,000 | – | 11,547,908 | – | 0.26% | – |
| ONCR | New | ONCORUS INC | $40,396,000 | – | 2,927,198 | – | 0.26% | – |
| CLOV | New | CLOVER HEALTH INVESTMENTS CO | $39,960,000 | – | 3,000,000 | – | 0.26% | – |
| VRNA | New | VERONA PHARMA PLCsponsored ads | $37,786,000 | – | 5,777,778 | – | 0.24% | – |
| DAWN | New | DAY ONE BIOPHARMACEUTICALS I | $34,430,000 | – | 1,512,094 | – | 0.22% | – |
| ONEM | New | 1LIFE HEALTHCARE INC | $34,120,000 | – | 1,032,088 | – | 0.22% | – |
| CMIIU | New | CM LIFE SCIENCES II INCunit 02/25/2028 | $33,626,000 | – | 2,500,000 | – | 0.22% | – |
| TDOC | New | TELADOC HEALTH INCcall | $33,258,000 | – | 200,000 | – | 0.22% | – |
| New | CATABASIS PHARMACEUTICALS IN | $32,438,000 | – | 15,374,370 | – | 0.21% | – | |
| New | NANOSTRING TECHNOLOGIES INCnote 2.625% 3/0 | $32,388,000 | – | 2,000,000 | – | 0.21% | – | |
| IMCR | New | IMMUNOCORE HLDGS PLCads | $31,240,000 | – | 800,000 | – | 0.20% | – |
| NEPT | New | NEPTUNE WELLNESS SOLUTIONS I | $30,068,000 | – | 25,699,412 | – | 0.20% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $29,852,000 | – | 1,700,000 | – | 0.19% | – |
| HCAQ | New | HEALTHCOR CATALIO ACQU CORPcl a shrs | $29,550,000 | – | 3,000,000 | – | 0.19% | – |
| NBTX | New | NANOBIOTIX SAsponsored ads | $29,208,000 | – | 2,119,600 | – | 0.19% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $29,062,000 | – | 1,589,012 | – | 0.19% | – |
| ADPT | New | ADAPTIVE BIOTECHNOLOGIES COR | $28,832,000 | – | 705,608 | – | 0.19% | – |
| FUSN | New | FUSION PHARMACEUTICALS INC | $28,686,000 | – | 3,550,334 | – | 0.19% | – |
| VTRS | New | VIATRIS INC | $28,706,000 | – | 2,008,838 | – | 0.19% | – |
| LPTX | New | LEAP THERAPEUTICS INC | $27,802,000 | – | 16,952,992 | – | 0.18% | – |
| HRMY | New | HARMONY BIOSCIENCES HLDGS IN | $27,740,000 | – | 982,664 | – | 0.18% | – |
| CMLTU | New | CM LIFE SCIENCES III INCunit 04/30/2028 | $27,376,000 | – | 2,500,000 | – | 0.18% | – |
| ACCD | New | ACCOLADE INC | $26,692,000 | – | 491,482 | – | 0.17% | – |
| CVRX | New | CVRX INC | $24,640,000 | – | 880,000 | – | 0.16% | – |
| BLSA | New | BCLS ACQUISITION CORP | $21,060,000 | – | 2,000,000 | – | 0.14% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $20,774,000 | – | 3,281,914 | – | 0.14% | – |
| RACB | New | RESEARCH ALLIANCE CORP II | $20,280,000 | – | 2,000,000 | – | 0.13% | – |
| SMIHU | New | SUMMIT HEALTHCRE ACQUISTN COunit 06/03/2026 | $20,020,000 | – | 2,000,000 | – | 0.13% | – |
| DNAY | New | CODEX DNA INC | $18,700,000 | – | 850,000 | – | 0.12% | – |
| CNCE | New | CONCERT PHARMACEUTICALS INC | $18,150,000 | – | 4,301,282 | – | 0.12% | – |
| FDMT | New | 4D MOLECULAR THERAPEUTICS IN | $18,072,000 | – | 750,512 | – | 0.12% | – |
| PRVB | New | PROVENTION BIO INC | $15,992,000 | – | 1,896,962 | – | 0.10% | – |
| PSTX | New | POSEIDA THERAPEUTICS INC | $15,786,000 | – | 1,575,490 | – | 0.10% | – |
| RACA | New | THERAPEUTICS ACQUISITION COR | $15,405,000 | – | 1,500,000 | – | 0.10% | – |
| ACHL | New | ACHILLES THERAPEUTICS PLCsponsored ads | $14,790,000 | – | 1,510,750 | – | 0.10% | – |
| SILK | New | SILK RD MED INC | $14,084,000 | – | 294,266 | – | 0.09% | – |
| New | DARIOHEALTH CORP | $14,006,000 | – | 655,738 | – | 0.09% | – | |
| TSHA | New | TAYSHA GENE THERAPIES INC | $13,586,000 | – | 640,880 | – | 0.09% | – |
| PRVA | New | PRIVIA HEALTH GROUP INC | $11,980,000 | – | 270,000 | – | 0.08% | – |
| AKYA | New | AKOYA BIOSCIENCES INC | $11,604,000 | – | 600,000 | – | 0.08% | – |
| BCTG | New | BCTG ACQUISITION CORP | $11,380,000 | – | 1,000,000 | – | 0.07% | – |
| MREO | New | MEREO BIOPHARMA GROUP PLCads | $10,754,000 | – | 3,392,136 | – | 0.07% | – |
| CHFWU | New | CONSONANCE HFW ACQUISITION Cunit 99/99/9999 | $10,400,000 | – | 1,000,000 | – | 0.07% | – |
| PRTA | New | PROTHENA CORP PLC | $10,282,000 | – | 200,000 | – | 0.07% | – |
| LGVU | New | LONGVIEW ACQUISITION CORP IIunit 99/99/9999 | $10,080,000 | – | 1,000,000 | – | 0.06% | – |
| HSAQ | New | HEALTH SCIENCES ACQ CORP 2 | $9,180,000 | – | 900,000 | – | 0.06% | – |
| TARA | New | PROTARA THERAPEUTICS INC | $8,214,000 | – | 843,282 | – | 0.05% | – |
| MRUS | New | MERUS NV | $7,374,000 | – | 350,000 | – | 0.05% | – |
| AMWL | New | AMERICAN WELL CORPcl a | $7,296,000 | – | 580,000 | – | 0.05% | – |
| RGNX | New | REGENXBIO INC | $6,938,000 | – | 178,566 | – | 0.04% | – |
| CMLF | New | CM LIFE SCIENCES INC | $6,360,000 | – | 454,000 | – | 0.04% | – |
| FULC | New | FULCRUM THERAPEUTICS INC | $6,164,000 | – | 588,236 | – | 0.04% | – |
| LSAQ | New | LIFESCI ACQUISITION II CORP | $6,000,000 | – | 600,000 | – | 0.04% | – |
| GRTX | New | GALERA THERAPEUTICS INC | $5,006,000 | – | 509,328 | – | 0.03% | – |
| FREQ | New | FREQUENCY THERAPEUTICS INC | $4,426,000 | – | 444,444 | – | 0.03% | – |
| CEREW | New | CEREVEL THERAPEUTICS HLDNG I*w exp 06/09/202 | $3,828,000 | – | 266,132 | – | 0.02% | – |
| MOTS | New | MOTUS GI HLDGS INC | $3,746,000 | – | 3,601,084 | – | 0.02% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $2,596,000 | – | 133,310 | – | 0.02% | – |
| RACE | New | FERRARI N V | $2,556,000 | – | 12,400 | – | 0.02% | – |
| SGTX | New | SIGILON THERAPEUTICS INC | $2,682,000 | – | 250,000 | – | 0.02% | – |
| BFLYWS | New | BUTTERFLY NETWORK INC*w exp 02/12/202 | $2,254,000 | – | 466,666 | – | 0.02% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $2,384,000 | – | 279,780 | – | 0.02% | – |
| SCPEWS | New | SC HEALTH CORP*w exp 99/99/999 | $2,110,000 | – | 1,000,000 | – | 0.01% | – |
| PLXP | New | PLX PHARMA INC | $1,586,000 | – | 114,918 | – | 0.01% | – |
| TKNO | New | ALPHA TEKNOVA INC | $1,424,000 | – | 60,000 | – | 0.01% | – |
| TCRR | New | TCR2 THERAPEUTICS INC | $1,010,000 | – | 61,506 | – | 0.01% | – |
| PHVS | New | PHARVARIS NV | $1,006,000 | – | 54,000 | – | 0.01% | – |
| CMAXW | New | CAREMAX INC*w exp 06/08/202 | $566,000 | – | 120,000 | – | 0.00% | – |
| RAPT | New | RAPT THERAPEUTICS INCput | $166,000 | – | 90,000 | – | 0.00% | – |
Q4 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| OTLKW | Exit | OUTLOOK THERAPEUTICS INC*w exp 02/18/202 | $0 | – | -420,875 | – | -0.00% | – |
| BIO | Exit | BIO RAD LABS INCcl a | $0 | – | -489 | – | -0.00% | – |
| REPL | Exit | REPLIMUNE GROUP INC | $0 | – | -19,230 | – | -0.01% | – |
| CVET | Exit | COVETRUS INC | $0 | – | -26,075 | – | -0.01% | – |
| PSNL | Exit | PERSONALIS INC | $0 | – | -27,272 | – | -0.01% | – |
| AKRO | Exit | AKERO THERAPEUTICS INC | $0 | – | -21,938 | – | -0.01% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -66,655 | – | -0.01% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -49,751 | – | -0.01% | – |
| LEGN | Exit | LEGEND BIOTECH CORPsponsored ads | $0 | – | -25,000 | – | -0.01% | – |
| TGTX | Exit | TG THERAPEUTICS INC | $0 | – | -33,893 | – | -0.01% | – |
| RACE | Exit | FERRARI N V | $0 | – | -6,200 | – | -0.02% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -139,890 | – | -0.02% | – |
| LVGO | Exit | LIVONGO HEALTH INC | $0 | – | -10,663 | – | -0.02% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -114,674 | – | -0.02% | – | |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -5,000 | – | -0.04% | – |
| GRTX | Exit | GALERA THERAPEUTICS INC | $0 | – | -325,000 | – | -0.04% | – |
| DFHTU | Exit | DEERFIELD HEALTHCARE TECH ACunit 07/16/2025 | $0 | – | -300,000 | – | -0.05% | – |
| ADAP | Exit | ADAPTIMMUNE THERAPEUTICS PLCsponds adr | $0 | – | -400,000 | – | -0.05% | – |
| ATEC | Exit | ALPHATEC HLDGS INC | $0 | – | -561,574 | – | -0.05% | – |
| BNR | Exit | BURNING ROCK BIOTECH LTDsponsored ads | $0 | – | -150,000 | – | -0.06% | – |
| MOTS | Exit | MOTUS GI HLDGS INC | $0 | – | -4,210,542 | – | -0.06% | – |
| LSACU | Exit | LIFESCI ACQUISITION CORPunit 03/31/2025 | $0 | – | -300,000 | – | -0.06% | – |
| TBIO | Exit | TRANSLATE BIO INC | $0 | – | -315,237 | – | -0.06% | – |
| VERU | Exit | VERU INC | $0 | – | -1,650,000 | – | -0.06% | – |
| HSAQ | Exit | HEALTH SCIENCES ACQ CORP 2 | $0 | – | -450,000 | – | -0.07% | – |
| BCTG | Exit | BCTG ACQUISITION CORP | $0 | – | -500,000 | – | -0.08% | – |
| PSTX | Exit | POSEIDA THERAPEUTICS INC | $0 | – | -787,745 | – | -0.10% | – |
| LGVWU | Exit | LONGVIEW ACQUISITION CORPunit 99/99/9999 | $0 | – | -700,000 | – | -0.10% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -224,224 | – | -0.11% | – |
| ONEM | Exit | 1LIFE HEALTHCARE INC | $0 | – | -279,844 | – | -0.12% | – |
| DYN | Exit | DYNE THERAPEUTICS INC | $0 | – | -400,000 | – | -0.12% | – |
| TCRR | Exit | TCR2 THERAPEUTICS INC | $0 | – | -400,000 | – | -0.12% | – |
| AQST | Exit | AQUESTIVE THERAPEUTICS INC | $0 | – | -1,750,000 | – | -0.12% | – |
| TWST | Exit | TWIST BIOSCIENCE CORP | $0 | – | -112,756 | – | -0.12% | – |
| AMRS | Exit | AMYRIS INC | $0 | – | -3,333,332 | – | -0.12% | – |
| VRAY | Exit | VIEWRAY INC | $0 | – | -2,451,748 | – | -0.12% | – |
| ATRC | Exit | ATRICURE INC | $0 | – | -216,449 | – | -0.13% | – |
| PODD | Exit | INSULET CORP | $0 | – | -37,733 | – | -0.13% | – |
| TARA | Exit | PROTARA THERAPEUTICS INC | $0 | – | -608,544 | – | -0.15% | – |
| TSHA | Exit | TAYSHA GENE THERAPIES INC | $0 | – | -470,440 | – | -0.15% | – |
| SCPEU | Exit | SC HEALTH CORPunit 99/99/9999 | $0 | – | -1,000,000 | – | -0.16% | – |
| HCAT | Exit | HEALTH CATALYST INC | $0 | – | -291,084 | – | -0.16% | – |
| HOLX | Exit | HOLOGIC INC | $0 | – | -170,000 | – | -0.16% | – |
| ACCD | Exit | ACCOLADE INC | $0 | – | -293,138 | – | -0.17% | – |
| DBVT | Exit | DBV TECHNOLOGIES S Asponsored adr | $0 | – | -6,806,975 | – | -0.17% | – |
| PPH | Exit | VANECK VECTORS ETF TRput | $0 | – | -200,000 | – | -0.18% | – |
| ESTA | Exit | ESTABLISHMENT LABS HLDGS INC | $0 | – | -678,633 | – | -0.18% | – |
| MORF | Exit | MORPHIC HLDG INC | $0 | – | -487,000 | – | -0.19% | – |
| AMWL | Exit | AMERICAN WELL CORPcl a | $0 | – | -455,000 | – | -0.20% | – |
| SLDB | Exit | SOLID BIOSCIENCES INC | $0 | – | -6,749,803 | – | -0.20% | – |
| DRNA | Exit | DICERNA PHARMACEUTICALS INC | $0 | – | -800,000 | – | -0.21% | – |
| HRMY | Exit | HARMONY BIOSCIENCES HLDGS IN | $0 | – | -435,377 | – | -0.22% | – |
| MYL | Exit | MYLAN N.V | $0 | – | -1,004,419 | – | -0.22% | – |
| LPTX | Exit | LEAP THERAPEUTICS INC | $0 | – | -8,476,496 | – | -0.24% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -2,577,043 | – | -0.25% | – |
| VRNA | Exit | VERONA PHARMA PLCsponsored ads | $0 | – | -2,888,889 | – | -0.26% | – |
| UMRX | Exit | UNUM THERAPEUTICS INC | $0 | – | -7,955,000 | – | -0.27% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -3,481,431 | – | -0.29% | – |
| CNCE | Exit | CONCERT PHARMACEUTICALS INC | $0 | – | -2,150,641 | – | -0.31% | – |
| WVE | Exit | WAVE LIFE SCIENCES LTD | $0 | – | -2,500,000 | – | -0.31% | – |
| PMVP | Exit | PMV PHARMACEUTICALS INC | $0 | – | -605,556 | – | -0.31% | – |
| RACA | Exit | THERAPEUTICS ACQUISITION COR | $0 | – | -1,500,000 | – | -0.32% | – |
| UROV | Exit | UROVANT SCIENCES LTD | $0 | – | -2,366,831 | – | -0.32% | – |
| XBI | Exit | SPDR SER TRput | $0 | – | -200,000 | – | -0.32% | – |
| STOK | Exit | STOKE THERAPEUTICS INC | $0 | – | -671,978 | – | -0.33% | – |
| GERN | Exit | GERON CORP | $0 | – | -13,461,538 | – | -0.34% | – |
| VRCA | Exit | VERRICA PHARMACEUTICALS INC | $0 | – | -3,410,412 | – | -0.38% | – |
| IMTX | Exit | IMMATICS N.V | $0 | – | -2,500,000 | – | -0.39% | – |
| FUSN | Exit | FUSION PHARMACEUTICALS INC | $0 | – | -2,235,983 | – | -0.39% | – |
| MTEM | Exit | MOLECULAR TEMPLATES INC | $0 | – | -2,474,133 | – | -0.39% | – |
| BIIB | Exit | BIOGEN INCcall | $0 | – | -100,000 | – | -0.41% | – |
| TPTX | Exit | TURNING POINT THERAPEUTICS I | $0 | – | -329,890 | – | -0.42% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -1,291,181 | – | -0.48% | – |
| ZNTL | Exit | ZENTALIS PHARMACEUTICALS INC | $0 | – | -1,050,003 | – | -0.50% | – |
| EIDX | Exit | EIDOS THERAPEUTICS INC | $0 | – | -686,922 | – | -0.51% | – |
| RNA | Exit | AVIDITY BIOSCIENCES INC | $0 | – | -1,235,818 | – | -0.51% | – |
| SILK | Exit | SILK RD MED INC | $0 | – | -520,100 | – | -0.51% | – |
| LYRA | Exit | LYRA THERAPEUTICS INC | $0 | – | -3,222,561 | – | -0.53% | – |
| CMPS | Exit | COMPASS PATHWAYS PLCsponsored ads | $0 | – | -1,047,404 | – | -0.53% | – |
| VYNE | Exit | VYNE THERAPEUTICS INC | $0 | – | -22,876,410 | – | -0.55% | – |
| ADMA | Exit | ADMA BIOLOGICS INC | $0 | – | -16,584,802 | – | -0.58% | – |
| ADPT | Exit | ADAPTIVE BIOTECHNOLOGIES COR | $0 | – | -830,000 | – | -0.59% | – |
| NEPT | Exit | NEPTUNE WELLNESS SOLUTIONS I | $0 | – | -19,436,906 | – | -0.60% | – |
| PCVX | Exit | VAXCYTE INC | $0 | – | -850,000 | – | -0.61% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -2,058,068 | – | -0.63% | – |
| ALLO | Exit | ALLOGENE THERAPEUTICS INC | $0 | – | -1,143,790 | – | -0.63% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INC | $0 | – | -6,285,458 | – | -0.68% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INC | $0 | – | -625,129 | – | -0.68% | – |
| AGRX | Exit | AGILE THERAPEUTICS INC | $0 | – | -15,919,925 | – | -0.71% | – |
| IMVT | Exit | IMMUNOVANT INC | $0 | – | -1,400,000 | – | -0.72% | – |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -2,189,010 | – | -0.73% | – |
| PRVB | Exit | PROVENTION BIO INC | $0 | – | -4,265,711 | – | -0.80% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS IN | $0 | – | -3,659,381 | – | -0.84% | – |
| ATHA | Exit | ATHIRA PHARMA INC | $0 | – | -3,114,805 | – | -0.84% | – |
| NARI | Exit | INARI MED INC | $0 | – | -848,500 | – | -0.86% | – |
| RTRX | Exit | RETROPHIN INC | $0 | – | -3,240,112 | – | -0.87% | – |
| KDMN | Exit | KADMON HLDGS INC | $0 | – | -15,711,334 | – | -0.90% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -664,574 | – | -0.90% | – |
| KOD | Exit | KODIAK SCIENCES INC | $0 | – | -1,043,021 | – | -0.90% | – |
| FMTX | Exit | FORMA THERAPEUTICS HLDGS INC | $0 | – | -1,250,000 | – | -0.91% | – |
| FREQ | Exit | FREQUENCY THERAPEUTICS INC | $0 | – | -3,256,518 | – | -0.91% | – |
| CHRS | Exit | COHERUS BIOSCIENCES INC | $0 | – | -3,636,485 | – | -0.97% | – |
| NVAX | Exit | NOVAVAX INC | $0 | – | -707,715 | – | -1.12% | – |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -912,140 | – | -1.13% | – |
| ALBO | Exit | ALBIREO PHARMA INC | $0 | – | -2,360,139 | – | -1.15% | – |
| QTNT | Exit | QUOTIENT LTD | $0 | – | -16,200,818 | – | -1.22% | – |
| MGTX | Exit | MEIRAGTX HLDGS PLC | $0 | – | -6,433,277 | – | -1.24% | – |
| RLAY | Exit | RELAY THERAPEUTICS INC | $0 | – | -2,329,407 | – | -1.45% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -1,341,308 | – | -1.64% | – |
| NVRO | Exit | NEVRO CORP | $0 | – | -826,164 | – | -1.68% | – |
| Exit | NEVRO CORPnote 2.750% 4/0 | $0 | – | -9,000,000 | – | -2.07% | – | |
| OM | Exit | OUTSET MED INC | $0 | – | -2,847,822 | – | -2.08% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -1,548,715 | – | -2.17% | – |
| VBIV | Exit | VBI VACCINES INC | $0 | – | -55,042,465 | – | -2.30% | – |
| ATNX | Exit | ATHENEX INC | $0 | – | -13,532,467 | – | -2.36% | – |
| Exit | COLLEGIUM PHARMACEUTICAL INCnote 2.625% 2/1 | $0 | – | -17,500,000 | – | -2.39% | – | |
| SWTX | Exit | SPRINGWORKS THERAPEUTICS INC | $0 | – | -3,481,148 | – | -2.42% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -1,395,017 | – | -2.78% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -4,400,999 | – | -2.99% | – |
| Exit | CYTOKINETICS INCnote 4.000%11/1 | $0 | – | -9,770,000 | – | -3.19% | – | |
| BBIO | Exit | BRIDGEBIO PHARMA INC | $0 | – | -6,706,268 | – | -3.67% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -5,800,996 | – | -4.67% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -10,085,632 | – | -4.85% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -25,122,048 | – | -5.18% | – |
| Exit | RETROPHIN INCnote 2.500% 9/1 | $0 | – | -45,000,000 | – | -5.70% | – | |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -3,435,575 | – | -8.33% | – |
Q3 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MRTX | Buy | MIRATI THERAPEUTICS INC | $570,477,000 | +80.3% | 3,435,575 | +24.0% | 8.33% | +62.5% |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $354,723,000 | -6.6% | 25,122,048 | -0.2% | 5.18% | -15.8% |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $332,019,000 | +2.4% | 10,085,632 | -14.6% | 4.85% | -7.7% |
| GBT | Sell | GLOBAL BLOOD THERAPEUTICS IN | $319,867,000 | -13.3% | 5,800,996 | -0.7% | 4.67% | -21.9% |
| Sell | CYTOKINETICS INCnote 4.000%11/1 | $218,301,000 | -8.4% | 9,770,000 | -2.3% | 3.19% | -17.5% | |
| ZYME | Buy | ZYMEWORKS INC | $204,999,000 | +58.7% | 4,400,999 | +22.9% | 2.99% | +43.0% |
| SWTX | Sell | SPRINGWORKS THERAPEUTICS INC | $165,946,000 | +12.4% | 3,481,148 | -0.9% | 2.42% | +1.3% |
| ATNX | Buy | ATHENEX INC | $161,323,000 | +3.5% | 13,532,467 | +17.3% | 2.36% | -6.8% |
| NBIX | Sell | NEUROCRINE BIOSCIENCES INC | $148,924,000 | -43.0% | 1,548,715 | -27.7% | 2.17% | -48.6% |
| OM | New | OUTSET MED INC | $142,391,000 | – | 2,847,822 | – | 2.08% | – |
| NVRO | Sell | NEVRO CORP | $115,085,000 | +7.0% | 826,164 | -8.2% | 1.68% | -3.6% |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $112,187,000 | – | 1,341,308 | – | 1.64% | – |
| RLAY | New | RELAY THERAPEUTICS INC | $99,209,000 | – | 2,329,407 | – | 1.45% | – |
| QTNT | Buy | QUOTIENT LTD | $83,272,000 | -15.3% | 16,200,818 | +21.9% | 1.22% | -23.7% |
| ALBO | Buy | ALBIREO PHARMA INC | $78,758,000 | +51.7% | 2,360,139 | +20.4% | 1.15% | +36.7% |
| IMMU | Buy | IMMUNOMEDICS INC | $77,559,000 | +504.3% | 912,140 | +151.9% | 1.13% | +444.2% |
| NVAX | Buy | NOVAVAX INC | $76,681,000 | +162.8% | 707,715 | +102.2% | 1.12% | +136.8% |
| CHRS | Buy | COHERUS BIOSCIENCES INC | $66,693,000 | +584.8% | 3,636,485 | +566.9% | 0.97% | +516.5% |
| FREQ | Buy | FREQUENCY THERAPEUTICS INC | $62,558,000 | -11.3% | 3,256,518 | +7.3% | 0.91% | -20.1% |
| KOD | Sell | KODIAK SCIENCES INC | $61,757,000 | -67.5% | 1,043,021 | -70.3% | 0.90% | -70.7% |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $61,606,000 | +14.7% | 664,574 | -3.5% | 0.90% | +3.3% |
| NARI | Buy | INARI MED INC | $58,563,000 | +73.7% | 848,500 | +21.9% | 0.86% | +56.6% |
| ATHA | New | ATHIRA PHARMA INC | $57,499,000 | – | 3,114,805 | – | 0.84% | – |
| PRVB | Sell | PROVENTION BIO INC | $54,729,000 | -14.3% | 4,265,711 | -5.7% | 0.80% | -22.8% |
| IMVT | Buy | IMMUNOVANT INC | $49,266,000 | +83.9% | 1,400,000 | +27.3% | 0.72% | +65.7% |
| ARNA | Sell | ARENA PHARMACEUTICALS INC | $46,753,000 | -32.2% | 625,129 | -42.9% | 0.68% | -38.9% |
| ALDX | Buy | ALDEYRA THERAPEUTICS INC | $46,575,000 | +262.0% | 6,285,458 | +103.7% | 0.68% | +226.9% |
| ALLO | Sell | ALLOGENE THERAPEUTICS INC | $43,132,000 | -34.8% | 1,143,790 | -25.9% | 0.63% | -41.2% |
| NEPT | Buy | NEPTUNE WELLNESS SOLUTIONS I | $41,012,000 | -20.6% | 19,436,906 | +5.4% | 0.60% | -28.4% |
| ADPT | Buy | ADAPTIVE BIOTECHNOLOGIES COR | $40,363,000 | +73.8% | 830,000 | +72.9% | 0.59% | +56.6% |
| VYNE | New | VYNE THERAPEUTICS INC | $37,975,000 | – | 22,876,410 | – | 0.55% | – |
| CMPS | New | COMPASS PATHWAYS PLCsponsored ads | $36,554,000 | – | 1,047,404 | – | 0.53% | – |
| SILK | Buy | SILK RD MED INC | $34,956,000 | +116.7% | 520,100 | +35.1% | 0.51% | +95.4% |
| MGNX | Buy | MACROGENICS INC | $32,525,000 | -9.6% | 1,291,181 | +0.2% | 0.48% | -18.5% |
| BIIB | New | BIOGEN INCcall | $28,368,000 | – | 100,000 | – | 0.41% | – |
| IMTX | New | IMMATICS N.V | $26,525,000 | – | 2,500,000 | – | 0.39% | – |
| XBI | New | SPDR SER TRput | $22,286,000 | – | 200,000 | – | 0.32% | – |
| RACA | New | THERAPEUTICS ACQUISITION COR | $21,570,000 | – | 1,500,000 | – | 0.32% | – |
| PMVP | New | PMV PHARMACEUTICALS INC | $21,497,000 | – | 605,556 | – | 0.31% | – |
| WVE | New | WAVE LIFE SCIENCES LTD | $21,225,000 | – | 2,500,000 | – | 0.31% | – |
| UMRX | New | UNUM THERAPEUTICS INC | $18,615,000 | – | 7,955,000 | – | 0.27% | – |
| VRNA | New | VERONA PHARMA PLCsponsored ads | $18,027,000 | – | 2,888,889 | – | 0.26% | – |
| HRMY | New | HARMONY BIOSCIENCES HLDGS IN | $14,759,000 | – | 435,377 | – | 0.22% | – |
| AMWL | New | AMERICAN WELL CORPcl a | $13,486,000 | – | 455,000 | – | 0.20% | – |
| MORF | Sell | MORPHIC HLDG INC | $13,314,000 | -24.3% | 487,000 | -25.1% | 0.19% | -31.9% |
| ESTA | Sell | ESTABLISHMENT LABS HLDGS INC | $12,575,000 | -8.5% | 678,633 | -7.8% | 0.18% | -17.5% |
| PPH | New | VANECK VECTORS ETF TRput | $12,434,000 | – | 200,000 | – | 0.18% | – |
| DBVT | Sell | DBV TECHNOLOGIES S Asponsored adr | $11,776,000 | -63.3% | 6,806,975 | -7.0% | 0.17% | -67.0% |
| ACCD | New | ACCOLADE INC | $11,394,000 | – | 293,138 | – | 0.17% | – |
| HOLX | Sell | HOLOGIC INC | $11,300,000 | -13.8% | 170,000 | -26.1% | 0.16% | -22.2% |
| HCAT | Sell | HEALTH CATALYST INC | $10,654,000 | +8.8% | 291,084 | -13.3% | 0.16% | -1.9% |
| TSHA | New | TAYSHA GENE THERAPIES INC | $10,538,000 | – | 470,440 | – | 0.15% | – |
| TARA | New | PROTARA THERAPEUTICS INC | $10,242,000 | – | 608,544 | – | 0.15% | – |
| PODD | Sell | INSULET CORP | $8,927,000 | -12.9% | 37,733 | -28.4% | 0.13% | -21.7% |
| ATRC | Sell | ATRICURE INC | $8,636,000 | -63.7% | 216,449 | -59.1% | 0.13% | -67.3% |
| TWST | Sell | TWIST BIOSCIENCE CORP | $8,566,000 | -30.7% | 112,756 | -58.7% | 0.12% | -37.5% |
| AMRS | Buy | AMYRIS INC | $8,568,000 | +32.9% | 3,333,332 | +80.7% | 0.12% | +19.0% |
| TCRR | New | TCR2 THERAPEUTICS INC | $8,128,000 | – | 400,000 | – | 0.12% | – |
| DYN | New | DYNE THERAPEUTICS INC | $8,076,000 | – | 400,000 | – | 0.12% | – |
| ONEM | Buy | 1LIFE HEALTHCARE INC | $7,936,000 | -0.2% | 279,844 | +27.9% | 0.12% | -10.1% |
| RVMD | Sell | REVOLUTION MEDICINES INC | $7,803,000 | -29.4% | 224,224 | -35.9% | 0.11% | -36.3% |
| PSTX | New | POSEIDA THERAPEUTICS INC | $6,987,000 | – | 787,745 | – | 0.10% | – |
| BCTG | New | BCTG ACQUISITION CORP | $5,180,000 | – | 500,000 | – | 0.08% | – |
| HSAQ | New | HEALTH SCIENCES ACQ CORP 2 | $4,950,000 | – | 450,000 | – | 0.07% | – |
| DFHTU | New | DEERFIELD HEALTHCARE TECH ACunit 07/16/2025 | $3,189,000 | – | 300,000 | – | 0.05% | – |
| REGN | Sell | REGENERON PHARMACEUTICALS | $2,799,000 | -70.1% | 5,000 | -66.7% | 0.04% | -73.0% |
| LVGO | Sell | LIVONGO HEALTH INC | $1,493,000 | +45.8% | 10,663 | -21.7% | 0.02% | +29.4% |
| TGTX | Buy | TG THERAPEUTICS INC | $907,000 | +56.4% | 33,893 | +13.9% | 0.01% | +44.4% |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $738,000 | – | 49,751 | – | 0.01% | – |
| AKRO | New | AKERO THERAPEUTICS INC | $675,000 | – | 21,938 | – | 0.01% | – |
| CVET | New | COVETRUS INC | $636,000 | – | 26,075 | – | 0.01% | – |
| PSNL | New | PERSONALIS INC | $591,000 | – | 27,272 | – | 0.01% | – |
| REPL | New | REPLIMUNE GROUP INC | $443,000 | – | 19,230 | – | 0.01% | – |
| BIO | Sell | BIO RAD LABS INCcl a | $252,000 | -96.4% | 489 | -96.8% | 0.00% | -96.5% |
| AVDL | Exit | AVADEL PHARMACEUTICALS PLCsponsored adr | $0 | – | -8,681 | – | -0.00% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -11,418 | – | -0.01% | – |
| VIR | Exit | VIR BIOTECHNOLOGY INC | $0 | – | -13,024 | – | -0.01% | – |
| LMNX | Exit | LUMINEX CORP DEL | $0 | – | -18,926 | – | -0.01% | – |
| CCXI | Exit | CHEMOCENTRYX INC | $0 | – | -10,252 | – | -0.01% | – |
| CUE | Exit | CUE BIOPHARMA INC | $0 | – | -26,371 | – | -0.01% | – |
| KRMD | Exit | REPRO MED SYS INC | $0 | – | -74,813 | – | -0.01% | – |
| AKBA | Exit | AKEBIA THERAPEUTICS INC | $0 | – | -52,724 | – | -0.01% | – |
| KRTX | Exit | KARUNA THERAPEUTICS INC | $0 | – | -6,944 | – | -0.01% | – |
| MNTA | Exit | MOMENTA PHARMACEUTICALS INC | $0 | – | -30,637 | – | -0.02% | – |
| DVAX | Exit | DYNAVAX TECHNOLOGIES CORP | $0 | – | -176,950 | – | -0.02% | – |
| RVNC | Exit | REVANCE THERAPEUTICS INC | $0 | – | -65,839 | – | -0.03% | – |
| MDT | Exit | MEDTRONIC PLC | $0 | – | -20,000 | – | -0.03% | – |
| PHR | Exit | PHREESIA INC | $0 | – | -70,000 | – | -0.03% | – |
| IMMU | Exit | IMMUNOMEDICS INCput | $0 | – | -100,000 | – | -0.06% | – |
| AXSM | Exit | AXSOME THERAPEUTICS INC | $0 | – | -50,000 | – | -0.07% | – |
| VCRA | Exit | VOCERA COMMUNICATIONS INC | $0 | – | -290,000 | – | -0.10% | – |
| Exit | DERMTECH INC | $0 | – | -487,121 | – | -0.10% | – | |
| MRNA | Exit | MODERNA INCput | $0 | – | -100,000 | – | -0.10% | – |
| NLTX | Exit | NEOLEUKIN THERAPEUTICS INC | $0 | – | -537,425 | – | -0.14% | – |
| BLU | Exit | BELLUS HEALTH INC NEW | $0 | – | -1,125,000 | – | -0.19% | – |
| ALEC | Exit | ALECTOR INC | $0 | – | -511,731 | – | -0.20% | – |
| YMAB | Exit | Y-MABS THERAPEUTICS INC | $0 | – | -355,366 | – | -0.25% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -894,118 | – | -0.26% | – |
| Exit | DENALI THERAPEUTICS INC | $0 | – | -850,000 | – | -0.33% | – | |
| MNLO | Exit | MENLO THERAPEUTICS INC | $0 | – | -22,876,410 | – | -0.64% | – |
| BDTX | Exit | BLACK DIAMOND THERAPEUTICS I | $0 | – | -1,104,656 | – | -0.71% | – |
| AGIO | Exit | AGIO PHARMACEUTICALS INC | $0 | – | -900,000 | – | -0.78% | – |
| VAPO | Exit | VAPOTHERM INC | $0 | – | -1,338,760 | – | -0.89% | – |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -4,907,139 | – | -2.15% | – |
Q2 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FOLD | New | AMICUS THERAPEUTICS INC | $379,750,000 | – | 25,182,364 | – | 6.15% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $368,811,000 | – | 5,842,100 | – | 5.98% | – |
| New | RETROPHIN INCnote 2.500% 9/1 | $349,979,000 | – | 45,000,000 | – | 5.67% | – | |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $324,170,000 | – | 11,809,494 | – | 5.25% | – |
| MRTX | New | MIRATI THERAPEUTICS INC | $316,371,000 | – | 2,771,050 | – | 5.13% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $261,252,000 | – | 2,141,410 | – | 4.23% | – |
| New | CYTOKINETICS INCnote 4.000%11/1 | $238,260,000 | – | 10,000,000 | – | 3.86% | – | |
| BBIO | New | BRIDGEBIO PHARMA INC | $218,691,000 | – | 6,706,268 | – | 3.54% | – |
| KOD | New | KODIAK SCIENCES INC | $190,154,000 | – | 3,513,572 | – | 3.08% | – |
| VBIV | New | VBI VACCINES INC | $170,631,000 | – | 55,042,465 | – | 2.76% | – |
| New | COLLEGIUM PHARMACEUTICAL INCnote 2.625% 2/1 | $157,227,000 | – | 17,500,000 | – | 2.55% | – | |
| ATNX | New | ATHENEX INC | $155,935,000 | – | 11,532,467 | – | 2.53% | – |
| SWTX | New | SPRINGWORKS THERAPEUTICS INC | $147,603,000 | – | 3,514,358 | – | 2.39% | – |
| MYOK | New | MYOKARDIA INC | $134,787,000 | – | 1,395,017 | – | 2.18% | – |
| ZGNX | New | ZOGENIX INC | $132,542,000 | – | 4,907,139 | – | 2.15% | – |
| ZYME | New | ZYMEWORKS INC | $129,166,000 | – | 3,580,999 | – | 2.09% | – |
| New | NEVRO CORPnote 2.750% 4/0 | $121,500,000 | – | 9,000,000 | – | 1.97% | – | |
| NVRO | New | NEVRO CORP | $107,520,000 | – | 899,972 | – | 1.74% | – |
| QTNT | New | QUOTIENT LTD | $98,338,000 | – | 13,289,054 | – | 1.59% | – |
| MGTX | New | MEIRAGTX HOLDINGS PLC | $80,544,000 | – | 6,433,277 | – | 1.30% | – |
| KDMN | New | KADMON HLDGS INC | $80,442,000 | – | 15,711,334 | – | 1.30% | – |
| FREQ | New | FREQUENCY THERAPEUTICS INC | $70,547,000 | – | 3,034,296 | – | 1.14% | – |
| ARNA | New | ARENA PHARMACEUTICALS INC | $68,938,000 | – | 1,095,129 | – | 1.12% | – |
| ALLO | New | ALLOGENE THERAPEUTICS INC | $66,105,000 | – | 1,543,790 | – | 1.07% | – |
| PRVB | New | PROVENTION BIO INC | $63,858,000 | – | 4,525,711 | – | 1.04% | – |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $59,171,000 | – | 3,659,381 | – | 0.96% | – |
| FMTX | New | FORMA THERAPEUTICS HLDGS INC | $58,113,000 | – | 1,250,000 | – | 0.94% | – |
| VAPO | New | VAPOTHERM INC | $54,876,000 | – | 1,338,760 | – | 0.89% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $53,713,000 | – | 688,624 | – | 0.87% | – |
| ALBO | New | ALBIREO PHARMA INC | $51,924,000 | – | 1,960,139 | – | 0.84% | – |
| NEPT | New | NEPTUNE WELLNESS SOLUTIONS I | $51,623,000 | – | 18,436,906 | – | 0.84% | – |
| ADMA | New | ADMA BIOLOGICS INC | $48,593,000 | – | 16,584,802 | – | 0.79% | – |
| AGIO | New | AGIO PHARMACEUTICALS INC | $48,132,000 | – | 900,000 | – | 0.78% | – |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $45,816,000 | – | 2,189,010 | – | 0.74% | – |
| ZNTL | New | ZENTALIS PHARMACEUTICALS INC | $45,783,000 | – | 1,050,003 | – | 0.74% | – |
| AGRX | New | AGILE THERAPEUTICS INC | $44,257,000 | – | 15,919,925 | – | 0.72% | – |
| BDTX | New | BLACK DIAMOND THERAPEUTICS I | $43,996,000 | – | 1,104,656 | – | 0.71% | – |
| MNLO | New | MENLO THERAPEUTICS INC | $39,576,000 | – | 22,876,410 | – | 0.64% | – |
| VRCA | New | VERRICA PHARMACEUTICALS INC | $37,549,000 | – | 3,410,412 | – | 0.61% | – |
| LYRA | New | LYRA THERAPEUTICS INC | $36,543,000 | – | 3,222,561 | – | 0.59% | – |
| COLL | New | COLLEGIUM PHARMACEUTICAL INC | $36,016,000 | – | 2,058,068 | – | 0.58% | – |
| MGNX | New | MACROGENICS INC | $35,961,000 | – | 1,288,014 | – | 0.58% | – |
| FUSN | New | FUSION PHARMACEUTICALS INC | $35,955,000 | – | 2,235,983 | – | 0.58% | – |
| MTEM | New | MOLECULAR TEMPLATES INC | $34,118,000 | – | 2,474,133 | – | 0.55% | – |
| NARI | New | INARI MED INC | $33,714,000 | – | 696,000 | – | 0.55% | – |
| DBVT | New | DBV TECHNOLOGIES S Asponsored adr | $32,125,000 | – | 7,317,809 | – | 0.52% | – |
| RNA | New | AVIDITY BIOSCIENCES INC | $31,613,000 | – | 1,235,818 | – | 0.51% | – |
| EIDX | New | EIDOS THERAPEUTICS INC | $30,115,000 | – | 686,922 | – | 0.49% | – |
| GERN | New | GERON CORP | $29,346,000 | – | 13,461,538 | – | 0.48% | – |
| NVAX | New | NOVAVAX INC | $29,173,000 | – | 350,000 | – | 0.47% | – |
| RTRX | New | RETROPHIN INC | $28,871,000 | – | 3,240,112 | – | 0.47% | – |
| PCVX | New | VAXCYTE INC | $26,869,000 | – | 850,000 | – | 0.44% | – |
| IMVT | New | IMMUNOVANT INC | $26,785,000 | – | 1,100,000 | – | 0.43% | – |
| ATRC | New | ATRICURE INC | $23,768,000 | – | 528,776 | – | 0.38% | – |
| UROV | New | UROVANT SCIENCES LTD | $23,289,000 | – | 2,366,831 | – | 0.38% | – |
| ADPT | New | ADAPTIVE BIOTECHNOLOGIES COR | $23,222,000 | – | 480,000 | – | 0.38% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $21,467,000 | – | 2,577,043 | – | 0.35% | – |
| CNCE | New | CONCERT PHARMACEUTICALS INC | $21,398,000 | – | 2,150,641 | – | 0.35% | – |
| TPTX | New | TURNING POINT THERAPEUTICS I | $21,308,000 | – | 329,890 | – | 0.34% | – |
| New | DENALI THERAPEUTICS INC | $20,553,000 | – | 850,000 | – | 0.33% | – | |
| DRNA | New | DICERNA PHARMACEUTICALS INC | $20,320,000 | – | 800,000 | – | 0.33% | – |
| SLDB | New | SOLID BIOSCIENCES INC | $19,777,000 | – | 6,749,803 | – | 0.32% | – |
| ISEE | New | IVERIC BIO INC | $17,755,000 | – | 3,481,431 | – | 0.29% | – |
| MORF | New | MORPHIC HLDG INC | $17,583,000 | – | 650,000 | – | 0.28% | – |
| LPTX | New | LEAP THERAPEUTICS INC | $17,466,000 | – | 8,476,496 | – | 0.28% | – |
| MYL | New | MYLAN N.V | $16,151,000 | – | 1,004,419 | – | 0.26% | – |
| SILK | New | SILK RD MED INC | $16,132,000 | – | 385,100 | – | 0.26% | – |
| STOK | New | STOKE THERAPEUTICS INC | $16,013,000 | – | 671,978 | – | 0.26% | – |
| FULC | New | FULCRUM THERAPEUTICS INC | $15,768,000 | – | 894,118 | – | 0.26% | – |
| YMAB | New | Y-MABS THERAPEUTICS INC | $15,352,000 | – | 355,366 | – | 0.25% | – |
| ESTA | New | ESTABLISHMENT LABS HOLDINGS INC | $13,750,000 | – | 736,121 | – | 0.22% | – |
| HOLX | New | HOLOGIC INC | $13,110,000 | – | 230,000 | – | 0.21% | – |
| IMMU | New | IMMUNOMEDICS INC | $12,834,000 | – | 362,140 | – | 0.21% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $12,866,000 | – | 3,085,458 | – | 0.21% | – |
| ALEC | New | ALECTOR INC | $12,507,000 | – | 511,731 | – | 0.20% | – |
| TWST | New | TWIST BIOSCIENCE CORP | $12,356,000 | – | 272,756 | – | 0.20% | – |
| BLU | New | BELLUS HEALTH INC NEW | $11,576,000 | – | 1,125,000 | – | 0.19% | – |
| RVMD | New | REVOLUTION MEDICINES INC | $11,050,000 | – | 350,000 | – | 0.18% | – |
| PODD | New | INSULET CORP | $10,244,000 | – | 52,733 | – | 0.17% | – |
| SCPEU | New | SC HEALTH CORPunit 99/99/9999 | $10,110,000 | – | 1,000,000 | – | 0.16% | – |
| HCAT | New | HEALTH CATALYST INC | $9,795,000 | – | 335,782 | – | 0.16% | – |
| CHRS | New | COHERUS BIOSCIENCES INC | $9,739,000 | – | 545,285 | – | 0.16% | – |
| REGN | New | REGENERON PHARMACEUTICALS | $9,354,000 | – | 15,000 | – | 0.15% | – |
| NLTX | New | NEOLEUKIN THERAPEUTICS INC | $8,921,000 | – | 537,425 | – | 0.14% | – |
| AQST | New | AQUESTIVE THERAPEUTICS INC | $8,505,000 | – | 1,750,000 | – | 0.14% | – |
| ONEM | New | 1LIFE HEALTHCARE INC | $7,948,000 | – | 218,844 | – | 0.13% | – |
| LGVWU | New | LONGVIEW ACQUISITION CORPunit 99/99/9999 | $7,070,000 | – | 700,000 | – | 0.12% | – |
| BIO | New | BIO RAD LABS INCcl a | $6,993,000 | – | 15,489 | – | 0.11% | – |
| AMRS | New | AMYRIS INC | $6,449,000 | – | 1,844,612 | – | 0.10% | – |
| MRNA | New | MODERNA INCput | $6,421,000 | – | 100,000 | – | 0.10% | – |
| New | DERMTECH INC | $6,445,000 | – | 487,121 | – | 0.10% | – | |
| VCRA | New | VOCERA COMMUNICATIONS INC | $6,148,000 | – | 290,000 | – | 0.10% | – |
| TBIO | New | TRANSLATE BIO INC | $5,649,000 | – | 315,237 | – | 0.09% | – |
| MOTS | New | MOTUS GI HLDGS INC | $5,557,000 | – | 4,210,542 | – | 0.09% | – |
| VRAY | New | VIEWRAY INC | $5,492,000 | – | 2,451,748 | – | 0.09% | – |
| VERU | New | VERU INC | $5,511,000 | – | 1,650,000 | – | 0.09% | – |
| AXSM | New | AXSOME THERAPEUTICS INC | $4,114,000 | – | 50,000 | – | 0.07% | – |
| BNR | New | BURNING ROCK BIOTECH LTDsponsored ads | $4,052,000 | – | 150,000 | – | 0.07% | – |
| ADAP | New | ADAPTIMMUNE THERAPEUTICS PLCsponds adr | $4,004,000 | – | 400,000 | – | 0.06% | – |
| IMMU | New | IMMUNOMEDICS INCput | $3,544,000 | – | 100,000 | – | 0.06% | – |
| LSACU | New | LIFESCI ACQUISITION CORPunit 03/31/2025 | $3,300,000 | – | 300,000 | – | 0.05% | – |
| ATEC | New | ALPHATEC HLDGS INC | $2,639,000 | – | 561,574 | – | 0.04% | – |
| GRTX | New | GALERA THERAPEUTICS INC | $2,321,000 | – | 325,000 | – | 0.04% | – |
| PHR | New | PHREESIA INC | $1,979,000 | – | 70,000 | – | 0.03% | – |
| MDT | New | MEDTRONIC PLC | $1,834,000 | – | 20,000 | – | 0.03% | – |
| RVNC | New | REVANCE THERAPEUTICS INC | $1,608,000 | – | 65,839 | – | 0.03% | – |
| DVAX | New | DYNAVAX TECHNOLOGIES CORP | $1,570,000 | – | 176,950 | – | 0.02% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $1,343,000 | – | 139,890 | – | 0.02% | – |
| LVGO | New | LIVONGO HEALTH INC | $1,024,000 | – | 13,620 | – | 0.02% | – |
| RACE | New | FERRARI N.V | $1,060,000 | – | 6,200 | – | 0.02% | – |
| LEGN | New | LEGEND BIOTECH CORPsponsored ads | $1,064,000 | – | 25,000 | – | 0.02% | – |
| MNTA | New | MOMENTA PHARMACEUTICALS INC | $1,019,000 | – | 30,637 | – | 0.02% | – |
| New | TRILLIUM THERAPEUTICS INC | $928,000 | – | 114,674 | – | 0.02% | – | |
| KRTX | New | KARUNA THERAPEUTICS INC | $774,000 | – | 6,944 | – | 0.01% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $807,000 | – | 66,655 | – | 0.01% | – |
| AKBA | New | AKEBIA THERAPEUTICS INC | $716,000 | – | 52,724 | – | 0.01% | – |
| KRMD | New | REPRO MED SYS INC | $672,000 | – | 74,813 | – | 0.01% | – |
| CUE | New | CUE BIOPHARMA INC | $646,000 | – | 26,371 | – | 0.01% | – |
| CCXI | New | CHEMOCENTRYX INC | $590,000 | – | 10,252 | – | 0.01% | – |
| LMNX | New | LUMINEX CORP DEL | $616,000 | – | 18,926 | – | 0.01% | – |
| TGTX | New | TG THERAPEUTICS INC | $580,000 | – | 29,762 | – | 0.01% | – |
| VIR | New | VIR BIOTECHNOLOGY INC | $534,000 | – | 13,024 | – | 0.01% | – |
| APLS | New | APELLIS PHARMACEUTICALS INC | $373,000 | – | 11,418 | – | 0.01% | – |
| AVDL | New | AVADEL PHARMACEUTICALS PLCsponsored adr | $133,000 | – | 8,681 | – | 0.00% | – |
| OTLKW | New | OUTLOOK THERAPEUTICS INC*w exp 02/18/202 | $108,000 | – | 420,875 | – | 0.00% | – |
Q4 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| OTLKW | Exit | OUTLOOK THERAPEUTICS INC*w exp 02/18/202 | $0 | – | -420,875 | – | -0.00% | – |
| CFMS | Exit | CONFORMIS INC | $0 | – | -50,000 | – | -0.00% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INCput | $0 | – | -100,000 | – | -0.00% | – |
| ABEOW | Exit | ABEONA THERAPEUTICS INCw exp 12/24/201 | $0 | – | -659,636 | – | -0.00% | – |
| RARX | Exit | RA PHARMACEUTICALS INC | $0 | – | -14,455 | – | -0.01% | – |
| TNDM | Exit | TANDEM DIABETES CARE INC | $0 | – | -6,422 | – | -0.01% | – |
| GTHX | Exit | G1 THERAPEUTICS INC | $0 | – | -15,702 | – | -0.01% | – |
| Exit | ARQULE INC | $0 | – | -54,500 | – | -0.01% | – | |
| NTRA | Exit | NATERA INC | $0 | – | -14,549 | – | -0.01% | – |
| KPTI | Exit | KARYOPHARM THERAPEUTICS INC | $0 | – | -54,645 | – | -0.01% | – |
| MREO | Exit | MEREO BIOPHARMA GROUP PLCads | $0 | – | -179,419 | – | -0.01% | – |
| MEDP | Exit | MEDPACE HLDGS INC | $0 | – | -6,328 | – | -0.01% | – |
| ALNA | Exit | ALLENA PHARMACEUTICALS INC | $0 | – | -132,300 | – | -0.01% | – |
| ALLK | Exit | ALLAKOS INC | $0 | – | -6,444 | – | -0.01% | – |
| ZYNE | Exit | ZYNERBA PHARMACEUTICALS INCput | $0 | – | -200,000 | – | -0.02% | – |
| NVCR | Exit | NOVOCURE LTD | $0 | – | -9,489 | – | -0.02% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INCput | $0 | – | -200,000 | – | -0.02% | – |
| Exit | FIAT CHRYSLER AUTOMOBILES N | $0 | – | -62,000 | – | -0.02% | – | |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS INC | $0 | – | -30,738 | – | -0.02% | – |
| MDCO | Exit | MEDICINES CO | $0 | – | -19,532 | – | -0.03% | – |
| RACE | Exit | FERRARI N.V. | $0 | – | -6,200 | – | -0.03% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -2,666,190 | – | -0.03% | – |
| AXSM | Exit | AXSOME THERAPEUTICS INC | $0 | – | -53,879 | – | -0.03% | – |
| CRY | Exit | CRYOLIFE INC | $0 | – | -50,000 | – | -0.04% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -139,890 | – | -0.04% | – |
| SGEN | Exit | SEATTLE GENETICS INC | $0 | – | -17,000 | – | -0.04% | – |
| XBI | Exit | SPDR SERIES TRUSTput | $0 | – | -900,000 | – | -0.04% | – |
| CORV | Exit | CORREVIO PHARMA CORP | $0 | – | -1,000,000 | – | -0.05% | – |
| VCRA | Exit | VOCERA COMMUNICATIONS INC | $0 | – | -99,804 | – | -0.07% | – |
| BGNE | Exit | BEIGENE LTDput | $0 | – | -400,000 | – | -0.07% | – |
| ACST | Exit | ACASTI PHARMA INCcl a new | $0 | – | -1,779,882 | – | -0.09% | – |
| TWST | Exit | TWIST BIOSCIENCE CORP | $0 | – | -145,856 | – | -0.09% | – |
| VERU | Exit | VERU INC | $0 | – | -1,650,000 | – | -0.10% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -600,000 | – | -0.11% | – |
| ATEC | Exit | ALPHATEC HOLDINGS INC | $0 | – | -850,000 | – | -0.12% | – |
| HSACU | Exit | HEALTH SCIENCES ACQUISITIONS CORPunit 04/01/2024 | $0 | – | -400,000 | – | -0.12% | – |
| TBIO | Exit | TRANSLATE BIO INC | $0 | – | -435,000 | – | -0.12% | – |
| CERN | Exit | CERNER CORP | $0 | – | -65,000 | – | -0.12% | – |
| PRVB | Exit | PROVENTION BIO INC | $0 | – | -666,322 | – | -0.12% | – |
| SIC | Exit | SELECT INTERIOR CONCEPTS INCcl a | $0 | – | -440,000 | – | -0.15% | – |
| ORTX | Exit | ORCHARD THERAPETICS PLCads | $0 | – | -521,800 | – | -0.17% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS INC | $0 | – | -97,600 | – | -0.17% | – |
| HCAT | Exit | HEALTH CATALYST INC | $0 | – | -210,924 | – | -0.18% | – |
| Exit | AQUESTIVE THERAPEUTICS INC | $0 | – | -2,113,400 | – | -0.18% | – | |
| ZBH | Exit | ZIMMER BIOMET HLDGS INC | $0 | – | -50,000 | – | -0.18% | – |
| VRAY | Exit | VIEWRAY INC | $0 | – | -2,451,748 | – | -0.19% | – |
| MEIP | Exit | MEI PHARMA INC | $0 | – | -4,400,440 | – | -0.20% | – |
| ALEC | Exit | ALECTOR INC | $0 | – | -511,731 | – | -0.20% | – |
| Exit | TELADOC HEALTH INCnote 1.375% 5/1 | $0 | – | -5,000,000 | – | -0.20% | – | |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -1,520,355 | – | -0.21% | – |
| MOTS | Exit | MOTUS GI HLDGS INC | $0 | – | -4,210,542 | – | -0.22% | – |
| ADPT | Exit | ADAPTIVE BIOTECHNOLOGIES COR | $0 | – | -295,000 | – | -0.25% | – |
| IDYA | Exit | IDEAYA BIOSCIENCES INC | $0 | – | -1,141,484 | – | -0.26% | – |
| MRKR | Exit | MARKER THERAPEUTICS INC | $0 | – | -2,000,000 | – | -0.28% | – |
| SCPEU | Exit | SC HEALTH CORPunit 99/99/9999 | $0 | – | -1,000,000 | – | -0.28% | – |
| TXG | Exit | 10X GENOMICS INC | $0 | – | -220,000 | – | -0.30% | – |
| MORF | Exit | MORPHIC HOLDING INC | $0 | – | -650,000 | – | -0.32% | – |
| AGRX | Exit | AGILE THERAPEUTICS INC | $0 | – | -10,726,750 | – | -0.34% | – |
| CNCE | Exit | CONCERT PHARMACEUTICALS INC | $0 | – | -2,194,641 | – | -0.35% | – |
| MTEM | Exit | MOLECULAR TEMPLATES INC | $0 | – | -1,974,133 | – | -0.35% | – |
| STOK | Exit | STOKE THERAPEUTICS DEAL SHARES | $0 | – | -671,978 | – | -0.39% | – |
| MMSI | Exit | MERIT MEDICAL SYSTEMS INC | $0 | – | -528,788 | – | -0.43% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INC | $0 | – | -3,085,458 | – | -0.44% | – |
| VAPO | Exit | VAPOTHERM INC | $0 | – | -1,764,470 | – | -0.45% | – |
| EHTH | Exit | EHEALTH INC | $0 | – | -255,089 | – | -0.46% | – |
| UROV | Exit | UROVANT SCIENCES LTD | $0 | – | -2,246,547 | – | -0.57% | – |
| BIO | Exit | BIO-RAD LABORATORIES INC SHS-A- | $0 | – | -65,000 | – | -0.58% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -608,000 | – | -0.58% | – |
| YMAB | Exit | Y-MABS THERAPEUTICS INC | $0 | – | -854,940 | – | -0.60% | – |
| TPTX | Exit | TURNING POINT THERAPEUTICS I | $0 | – | -597,190 | – | -0.60% | – |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -1,977,412 | – | -0.62% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -1,198,182 | – | -0.62% | – |
| ESTA | Exit | ESTABLISHMENT LABS HOLDINGS INC | $0 | – | -1,260,528 | – | -0.64% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -3,253,923 | – | -0.65% | – |
| EIDX | Exit | EIDOS THERAPEUTICS INC | $0 | – | -686,992 | – | -0.67% | – |
| Exit | PROTAGONIST THERAPEUTICS INC | $0 | – | -2,071,297 | – | -0.67% | – | |
| DBVT | Exit | DBV TECHNOLOGIES SAsponsored adr | $0 | – | -3,609,084 | – | -0.84% | – |
| KDMN | Exit | KADMON HOLDINGS INC | $0 | – | -13,165,746 | – | -0.89% | – |
| ONCE | Exit | SPARK THERAPEUTICS INC | $0 | – | -350,000 | – | -0.91% | – |
| FOMX | Exit | FOAMIX PHARMACEUTICALS LTD | $0 | – | -11,203,881 | – | -0.92% | – |
| ALBO | Exit | ALBIREO PHARMA INC | $0 | – | -1,704,330 | – | -0.92% | – |
| MNTA | Exit | MOMENTA PHARMACEUTICALS INC | $0 | – | -2,905,000 | – | -1.01% | – |
| RTRX | Exit | RETROPHIN INC | $0 | – | -3,270,571 | – | -1.02% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS INC | $0 | – | -2,587,953 | – | -1.05% | – |
| ALLO | Exit | ALLOGENE THERAPEUTICS INC | $0 | – | -1,543,790 | – | -1.13% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INC | $0 | – | -953,129 | – | -1.18% | – |
| KOD | Exit | KODIAK SCIENCES INC | $0 | – | -3,135,199 | – | -1.22% | – |
| VBIV | Exit | VBI VACCINES INC | $0 | – | -45,951,556 | – | -1.24% | – |
| NEPT | Exit | NEPTUNE WELLNESS SOLUTIONS INC | $0 | – | -13,436,906 | – | -1.29% | – |
| VRCA | Exit | VERRICA PHARMACEUTICALS INC | $0 | – | -3,410,412 | – | -1.36% | – |
| ADMA | Exit | ADMA BIOLOGICS INC | $0 | – | -11,521,102 | – | -1.38% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -1,130,511 | – | -1.59% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -2,388,890 | – | -1.60% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -883,264 | – | -1.75% | – |
| SWTX | Exit | SPRINGWORKS THERAPEUTICS INC | $0 | – | -3,217,522 | – | -1.88% | – |
| SLDB | Exit | SOLID BIOSCIENCES INC | $0 | – | -6,749,803 | – | -1.88% | – |
| NVRO | Exit | NEVRO CORP | $0 | – | -974,773 | – | -2.26% | – |
| QTNT | Exit | QUOTIENT LTD | $0 | – | -10,789,054 | – | -2.26% | – |
| MGTX | Exit | MEIRAGTX HOLDINGS PLC | $0 | – | -6,433,277 | – | -2.76% | – |
| DOVA | Exit | DOVA PHARMACEUTICALS INC | $0 | – | -3,708,705 | – | -2.79% | – |
| AMRN | Exit | AMARIN CORPORATION PLCspons adr new | $0 | – | -7,636,079 | – | -3.12% | – |
| ATNX | Exit | ATHENEX INC | $0 | – | -10,735,245 | – | -3.52% | – |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -3,264,152 | – | -3.52% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INC | $0 | – | -6,706,268 | – | -3.88% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -24,609,700 | – | -5.32% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -11,014,702 | – | -5.40% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -3,314,606 | – | -6.96% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS INC | $0 | – | -5,875,726 | – | -7.68% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -4,059,900 | – | -9.86% | – |
Q3 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $365,837,000 | +7.7% | 4,059,900 | +0.9% | 9.86% | +26.4% |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS INC | $285,090,000 | -6.2% | 5,875,726 | +1.7% | 7.68% | +10.2% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $258,241,000 | -13.5% | 3,314,606 | +14.3% | 6.96% | +1.5% |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $200,467,000 | -31.4% | 11,014,702 | -7.6% | 5.40% | -19.4% |
| FOLD | Buy | AMICUS THERAPEUTICS INC | $197,369,000 | -26.5% | 24,609,700 | +14.4% | 5.32% | -13.7% |
| ZGNX | Sell | ZOGENIX INC | $130,696,000 | -22.0% | 3,264,152 | -6.9% | 3.52% | -8.4% |
| ATNX | Buy | ATHENEX INC | $130,594,000 | -30.4% | 10,735,245 | +9.3% | 3.52% | -18.3% |
| AMRN | Buy | AMARIN CORPORATION PLCspons adr new | $115,763,000 | -3.7% | 7,636,079 | +23.1% | 3.12% | +13.0% |
| DOVA | Buy | DOVA PHARMACEUTICALS INC | $103,658,000 | +106.9% | 3,708,705 | +4.4% | 2.79% | +142.9% |
| MGTX | Buy | MEIRAGTX HOLDINGS PLC | $102,610,000 | -34.1% | 6,433,277 | +7.1% | 2.76% | -22.7% |
| NVRO | Sell | NEVRO CORP | $83,801,000 | +13.6% | 974,773 | -14.3% | 2.26% | +33.4% |
| SLDB | Buy | SOLID BIOSCIENCES INC | $69,792,000 | +209.1% | 6,749,803 | +71.9% | 1.88% | +262.9% |
| SWTX | New | SPRINGWORKS THERAPEUTICS INC | $69,755,000 | – | 3,217,522 | – | 1.88% | – |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $64,893,000 | -43.3% | 883,264 | -27.2% | 1.75% | -33.4% |
| ZYME | Buy | ZYMEWORKS INC | $59,244,000 | +13.7% | 2,388,890 | +0.8% | 1.60% | +33.4% |
| MYOK | Buy | MYOKARDIA INC | $58,956,000 | +6.8% | 1,130,511 | +2.7% | 1.59% | +25.4% |
| NEPT | Buy | NEPTUNE WELLNESS SOLUTIONS INC | $47,835,000 | +59.6% | 13,436,906 | +51.1% | 1.29% | +87.4% |
| VBIV | Buy | VBI VACCINES INC | $45,951,000 | +86.7% | 45,951,556 | +77.1% | 1.24% | +119.1% |
| ARNA | Sell | ARENA PHARMACEUTICALS INC | $43,624,000 | -46.1% | 953,129 | -30.9% | 1.18% | -36.7% |
| RTRX | Sell | RETROPHIN INC | $37,905,000 | -50.0% | 3,270,571 | -13.3% | 1.02% | -41.3% |
| FOMX | Buy | FOAMIX PHARMACEUTICALS LTD | $34,060,000 | +207.0% | 11,203,881 | +140.3% | 0.92% | +260.0% |
| CTMX | Buy | CYTOMX THERAPEUTICS INC | $24,014,000 | -32.1% | 3,253,923 | +3.2% | 0.65% | -20.3% |
| NVTA | Sell | INVITAE CORP | $23,088,000 | -26.9% | 1,198,182 | -10.8% | 0.62% | -14.1% |
| TPTX | Buy | TURNING POINT THERAPEUTICS I | $22,454,000 | +29.8% | 597,190 | +40.5% | 0.60% | +52.4% |
| YMAB | New | Y-MABS THERAPEUTICS INC | $22,280,000 | – | 854,940 | – | 0.60% | – |
| RGNX | Sell | REGENXBIO INC | $21,645,000 | -56.6% | 608,000 | -37.4% | 0.58% | -49.1% |
| BIO | New | BIO-RAD LABORATORIES INC SHS-A- | $21,628,000 | – | 65,000 | – | 0.58% | – |
| UROV | Buy | UROVANT SCIENCES LTD | $21,275,000 | +43.4% | 2,246,547 | +19.8% | 0.57% | +68.5% |
| EHTH | Sell | EHEALTH INC | $17,037,000 | -48.7% | 255,089 | -33.9% | 0.46% | -39.8% |
| VAPO | Buy | VAPOTHERM INC | $16,709,000 | -48.3% | 1,764,470 | +25.6% | 0.45% | -39.3% |
| MMSI | Sell | MERIT MEDICAL SYSTEMS INC | $16,107,000 | -66.9% | 528,788 | -35.3% | 0.43% | -61.1% |
| CNCE | Sell | CONCERT PHARMACEUTICALS INC | $12,904,000 | -51.2% | 2,194,641 | -0.5% | 0.35% | -42.7% |
| AGRX | Buy | AGILE THERAPEUTICS INC | $12,711,000 | +21.7% | 10,726,750 | +27.3% | 0.34% | +42.5% |
| TXG | New | 10X GENOMICS INC | $11,088,000 | – | 220,000 | – | 0.30% | – |
| SCPEU | New | SC HEALTH CORPunit 99/99/9999 | $10,350,000 | – | 1,000,000 | – | 0.28% | – |
| ADPT | Buy | ADAPTIVE BIOTECHNOLOGIES COR | $9,116,000 | -33.8% | 295,000 | +3.5% | 0.25% | -22.2% |
| CBAY | Sell | CYMABAY THERAPEUTICS INC | $7,784,000 | -71.9% | 1,520,355 | -60.6% | 0.21% | -66.9% |
| New | TELADOC HEALTH INCnote 1.375% 5/1 | $7,398,000 | – | 5,000,000 | – | 0.20% | – | |
| VRAY | Sell | VIEWRAY INC | $7,110,000 | -85.2% | 2,451,748 | -55.1% | 0.19% | -82.6% |
| ZBH | New | ZIMMER BIOMET HLDGS INC | $6,864,000 | – | 50,000 | – | 0.18% | – |
| HCAT | New | HEALTH CATALYST INC | $6,674,000 | – | 210,924 | – | 0.18% | – |
| SIC | New | SELECT INTERIOR CONCEPTS INCcl a | $5,707,000 | – | 440,000 | – | 0.15% | – |
| PRVB | New | PROVENTION BIO INC | $4,548,000 | – | 666,322 | – | 0.12% | – |
| CERN | New | CERNER CORP | $4,431,000 | – | 65,000 | – | 0.12% | – |
| ATEC | New | ALPHATEC HOLDINGS INC | $4,267,000 | – | 850,000 | – | 0.12% | – |
| FULC | New | FULCRUM THERAPEUTICS INC | $3,984,000 | – | 600,000 | – | 0.11% | – |
| VERU | Buy | VERU INC | $3,564,000 | +15.8% | 1,650,000 | +14.2% | 0.10% | +35.2% |
| TWST | Buy | TWIST BIOSCIENCE CORP | $3,483,000 | +8.3% | 145,856 | +31.6% | 0.09% | +27.0% |
| BGNE | New | BEIGENE LTDput | $2,698,000 | – | 400,000 | – | 0.07% | – |
| VCRA | Sell | VOCERA COMMUNICATIONS INC | $2,460,000 | -60.4% | 99,804 | -48.7% | 0.07% | -53.5% |
| CORV | New | CORREVIO PHARMA CORP | $2,000,000 | – | 1,000,000 | – | 0.05% | – |
| XBI | Buy | SPDR SERIES TRUSTput | $1,604,000 | +2191.4% | 900,000 | +350.0% | 0.04% | +2050.0% |
| SGEN | New | SEATTLE GENETICS INC | $1,452,000 | – | 17,000 | – | 0.04% | – |
| ARWR | Sell | ARROWHEAD PHARMACEUTICALS INC | $866,000 | -90.1% | 30,738 | -90.7% | 0.02% | -88.6% |
| BMRN | New | BIOMARIN PHARMACEUTICAL INCput | $750,000 | – | 200,000 | – | 0.02% | – |
| NVCR | New | NOVOCURE LTD | $710,000 | – | 9,489 | – | 0.02% | – |
| ZYNE | New | ZYNERBA PHARMACEUTICALS INCput | $635,000 | – | 200,000 | – | 0.02% | – |
| MEDP | New | MEDPACE HLDGS INC | $532,000 | – | 6,328 | – | 0.01% | – |
| KPTI | New | KARYOPHARM THERAPEUTICS INC | $526,000 | – | 54,645 | – | 0.01% | – |
| ALLK | New | ALLAKOS INC | $507,000 | – | 6,444 | – | 0.01% | – |
| New | ARQULE INC | $391,000 | – | 54,500 | – | 0.01% | – | |
| GTHX | New | G1 THERAPEUTICS INC | $358,000 | – | 15,702 | – | 0.01% | – |
| RARX | New | RA PHARMACEUTICALS INC | $342,000 | – | 14,455 | – | 0.01% | – |
| MRTX | New | MIRATI THERAPEUTICS INCput | $145,000 | – | 100,000 | – | 0.00% | – |
| CFMS | New | CONFORMIS INC | $93,000 | – | 50,000 | – | 0.00% | – |
| SLDB | Exit | SOLID BIOSCIENCES INCcall | $0 | – | -200 | – | -0.00% | – |
| BIIB | Exit | BIOGEN INCcall | $0 | – | -200,000 | – | -0.00% | – |
| Exit | CONFORMIS INC | $0 | – | -100,000 | – | -0.01% | – | |
| ZIOP | Exit | ZIOPHARM ONCOLOGY INC | $0 | – | -90,498 | – | -0.01% | – |
| GH | Exit | GUARDANT HEALTH INC | $0 | – | -6,617 | – | -0.01% | – |
| FLDM | Exit | FLUIDIGM CORP | $0 | – | -46,030 | – | -0.01% | – |
| VYGR | Exit | VOYAGER THERAPEUTICS INC | $0 | – | -36,573 | – | -0.02% | – |
| RMTI | Exit | ROCKWELL MEDICAL INC | $0 | – | -1,500,000 | – | -0.10% | – |
| RYTM | Exit | RHYTHM PHARMACEUTICALS INC | $0 | – | -262,970 | – | -0.13% | – |
| THC | Exit | TENET HEALTHCARE CORP | $0 | – | -300,633 | – | -0.14% | – |
| SYBX | Exit | SYNLOGIC INC | $0 | – | -867,852 | – | -0.18% | – |
| MCRB | Exit | SERES THERAPEUTICS INC | $0 | – | -2,500,000 | – | -0.18% | – |
| SWAV | Exit | SHOCKWAVE MEDICAL INC | $0 | – | -150,000 | – | -0.20% | – |
| ACOR | Exit | ACORDA THERAPEUTICS INC | $0 | – | -1,127,318 | – | -0.20% | – |
| Exit | ANI PHARMACEUTICALS INCnote 3.000% 12/0 | $0 | – | -7,500,000 | – | -0.21% | – | |
| DXCM | Exit | DEXCOM INC | $0 | – | -60,000 | – | -0.21% | – |
| AXNX | Exit | AXONICS MODULATION TECHNOLOGIES INC | $0 | – | -285,502 | – | -0.27% | – |
| BHC | Exit | BAUSCH HEALTH COS INC | $0 | – | -600,000 | – | -0.35% | – |
| TDOC | Exit | TELADOC HEALTH INC | $0 | – | -307,021 | – | -0.47% | – |
| QURE | Exit | UNIQURE N.V | $0 | – | -281,820 | – | -0.50% | – |
| ARRY | Exit | ARRAY BIOPHARMA INC | $0 | – | -1,038,390 | – | -1.10% | – |
| ASND | Exit | ASCENDIS PHARMA A Ssponsored adr | $0 | – | -473,475 | – | -1.25% | – |
Q2 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $339,734,000 | – | 4,023,862 | – | 7.80% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS INC | $303,803,000 | – | 5,775,726 | – | 6.97% | – |
| MRTX | New | MIRATI THERAPEUTICS INC | $298,659,000 | – | 2,899,606 | – | 6.85% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $292,158,000 | – | 11,915,127 | – | 6.70% | – |
| FOLD | New | AMICUS THERAPEUTICS INC | $268,438,000 | – | 21,509,486 | – | 6.16% | – |
| ATNX | New | ATHENEX INC | $187,636,000 | – | 9,822,118 | – | 4.31% | – |
| BBIO | New | BRIDGEBIO PHARMA INC | $180,868,000 | – | 6,706,268 | – | 4.15% | – |
| ZGNX | New | ZOGENIX INC | $167,575,000 | – | 3,507,223 | – | 3.84% | – |
| MGTX | New | MEIRAGTX HOLDINGS PLC | $155,766,000 | – | 6,007,746 | – | 3.57% | – |
| AMRN | New | AMARIN CORPORATION PLCspons adr new | $120,242,000 | – | 6,201,269 | – | 2.76% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $114,397,000 | – | 1,212,731 | – | 2.62% | – |
| QTNT | New | QUOTIENT LTD | $100,877,000 | – | 10,789,054 | – | 2.32% | – |
| ARNA | New | ARENA PHARMACEUTICALS INC | $80,919,000 | – | 1,380,171 | – | 1.86% | – |
| RTRX | New | RETROPHIN INC | $75,791,000 | – | 3,772,582 | – | 1.74% | – |
| NVRO | New | NEVRO CORP | $73,761,000 | – | 1,137,765 | – | 1.69% | – |
| CRNX | New | CRINETICS PHARMACEUTICALS INC | $64,698,000 | – | 2,587,953 | – | 1.48% | – |
| MYOK | New | MYOKARDIA INC | $55,180,000 | – | 1,100,511 | – | 1.27% | – |
| ALBO | New | ALBIREO PHARMA INC | $54,948,000 | – | 1,704,330 | – | 1.26% | – |
| ASND | New | ASCENDIS PHARMA A Ssponsored adr | $54,521,000 | – | 473,475 | – | 1.25% | – |
| ZYME | New | ZYMEWORKS INC | $52,115,000 | – | 2,368,890 | – | 1.20% | – |
| DOVA | New | DOVA PHARMACEUTICALS INC | $50,098,000 | – | 3,553,060 | – | 1.15% | – |
| RGNX | New | REGENXBIO INC | $49,880,000 | – | 970,997 | – | 1.14% | – |
| MMSI | New | MERIT MEDICAL SYSTEMS INC | $48,673,000 | – | 817,209 | – | 1.12% | – |
| ARRY | New | ARRAY BIOPHARMA INC | $48,109,000 | – | 1,038,390 | – | 1.10% | – |
| VRAY | New | VIEWRAY INC | $48,061,000 | – | 5,455,243 | – | 1.10% | – |
| ADMA | New | ADMA BIOLOGICS INC | $44,586,000 | – | 11,521,102 | – | 1.02% | – |
| ALLO | New | ALLOGENE THERAPEUTICS INC | $41,450,000 | – | 1,543,790 | – | 0.95% | – |
| VRCA | New | VERRICA PHARMACEUTICALS INC | $39,628,000 | – | 3,410,412 | – | 0.91% | – |
| KOD | New | KODIAK SCIENCES INC | $36,681,000 | – | 3,135,199 | – | 0.84% | – |
| MNTA | New | MOMENTA PHARMACEUTICALS INC | $36,167,000 | – | 2,905,000 | – | 0.83% | – |
| ONCE | New | SPARK THERAPEUTICS INC | $35,833,000 | – | 350,000 | – | 0.82% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $35,387,000 | – | 3,153,923 | – | 0.81% | – |
| EHTH | New | EHEALTH INC | $33,233,000 | – | 385,982 | – | 0.76% | – |
| VAPO | New | VAPOTHERM INC | $32,302,000 | – | 1,404,470 | – | 0.74% | – |
| NVTA | New | INVITAE CORP | $31,572,000 | – | 1,343,491 | – | 0.72% | – |
| NEPT | New | NEPTUNE WELLNESS SOLUTIONS INC | $29,978,000 | – | 8,891,452 | – | 0.69% | – |
| DBVT | New | DBV TECHNOLOGIES S Asponsored adr | $29,666,000 | – | 3,609,084 | – | 0.68% | – |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $29,661,000 | – | 1,977,412 | – | 0.68% | – |
| ESTA | New | ESTABLISHMENT LABS HLDGS INC | $27,719,000 | – | 1,260,528 | – | 0.64% | – |
| CBAY | New | CYMABAY THERAPEUTICS INC | $27,657,000 | – | 3,862,821 | – | 0.64% | – |
| KDMN | New | KADMON HOLDINGS INC | $27,121,000 | – | 13,165,746 | – | 0.62% | – |
| CNCE | New | CONCERT PHARMACEUTICALS INC | $26,456,000 | – | 2,204,641 | – | 0.61% | – |
| New | PROTAGONIST THERAPEUTICS INC | $25,083,000 | – | 2,071,297 | – | 0.58% | – | |
| VBIV | New | VBI VACCINES INC | $24,607,000 | – | 25,951,556 | – | 0.56% | – |
| SLDB | New | SOLID BIOSCIENCES INC | $22,581,000 | – | 3,927,222 | – | 0.52% | – |
| QURE | New | UNIQURE N.V | $22,024,000 | – | 281,820 | – | 0.50% | – |
| EIDX | New | EIDOS THERAPEUTICS INC | $21,349,000 | – | 686,992 | – | 0.49% | – |
| TDOC | New | TELADOC HEALTH INC | $20,389,000 | – | 307,021 | – | 0.47% | – |
| STOK | New | STOKE THERAPEUTICS INC | $19,601,000 | – | 671,978 | – | 0.45% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $18,512,000 | – | 3,085,458 | – | 0.42% | – |
| TPTX | New | TURNING POINT THERAPEUTICS I | $17,296,000 | – | 424,968 | – | 0.40% | – |
| MTEM | New | MOLECULAR TEMPLATES INC | $16,484,000 | – | 1,974,133 | – | 0.38% | – |
| MRKR | New | MARKER THERAPEUTICS INC | $15,840,000 | – | 2,000,000 | – | 0.36% | – |
| BHC | New | BAUSCH HEALTH COS INC | $15,132,000 | – | 600,000 | – | 0.35% | – |
| UROV | New | UROVANT SCIENCES LTD | $14,835,000 | – | 1,875,426 | – | 0.34% | – |
| ADPT | New | ADAPTIVE BIOTECHNOLOGIES COR | $13,766,000 | – | 285,000 | – | 0.32% | – |
| MORF | New | MORPHIC HOLDING INC | $12,883,000 | – | 650,000 | – | 0.30% | – |
| MOTS | New | MOTUS GI HLDGS INC | $12,757,000 | – | 4,210,542 | – | 0.29% | – |
| AXNX | New | AXONICS MODULATION TECHNOLOGIES INC | $11,697,000 | – | 285,502 | – | 0.27% | – |
| IDYA | New | IDEAYA BIOSCIENCES INC | $11,369,000 | – | 1,141,484 | – | 0.26% | – |
| FOMX | New | FOAMIX PHARMACEUTICALS LTD | $11,095,000 | – | 4,661,824 | – | 0.26% | – |
| MEIP | New | MEI PHARMA INC | $11,001,000 | – | 4,400,440 | – | 0.25% | – |
| AGRX | New | AGILE THERAPEUTICS INC | $10,443,000 | – | 8,426,750 | – | 0.24% | – |
| New | FIAT CHRYSLER AUTOMOBILES N | $10,008,000 | – | 62,000 | – | 0.23% | – | |
| ALEC | New | ALECTOR INC | $9,325,000 | – | 511,731 | – | 0.21% | – |
| New | ANI PHARMACEUTICALS INCnote 3.000% 12/0 | $8,992,000 | – | 7,500,000 | – | 0.21% | – | |
| DXCM | New | DEXCOM INC | $8,990,000 | – | 60,000 | – | 0.21% | – |
| New | AQUESTIVE THERAPEUTICS INC | $8,876,000 | – | 2,113,400 | – | 0.20% | – | |
| ARWR | New | ARROWHEAD PHARMACEUTICALS INC | $8,765,000 | – | 330,738 | – | 0.20% | – |
| ACOR | New | ACORDA THERAPEUTICS INC | $8,647,000 | – | 1,127,318 | – | 0.20% | – |
| SWAV | New | SHOCKWAVE MEDICAL INC | $8,564,000 | – | 150,000 | – | 0.20% | – |
| MCRB | New | SERES THERAPEUTICS INC | $8,050,000 | – | 2,500,000 | – | 0.18% | – |
| SYBX | New | SYNLOGIC INC | $7,897,000 | – | 867,852 | – | 0.18% | – |
| ICPT | New | INTERCEPT PHARMACEUTICALS INC | $7,766,000 | – | 97,600 | – | 0.18% | – |
| ORTX | New | ORCHARD THERAPEUTICS PLCads | $7,299,000 | – | 521,800 | – | 0.17% | – |
| THC | New | TENET HEALTHCARE CORP | $6,211,000 | – | 300,633 | – | 0.14% | – |
| VCRA | New | VOCERA COMMUNICATIONS INC | $6,205,000 | – | 194,400 | – | 0.14% | – |
| RYTM | New | RHYTHM PHARMACEUTICALS INC | $5,785,000 | – | 262,970 | – | 0.13% | – |
| TBIO | New | TRANSLATE BIO INC | $5,494,000 | – | 435,000 | – | 0.13% | – |
| RMTI | New | ROCKWELL MEDICAL INC | $4,515,000 | – | 1,500,000 | – | 0.10% | – |
| HSACU | New | HEALTH SCIENCES ACQUISITIONS CORPunit 04/01/2024 | $4,241,000 | – | 400,000 | – | 0.10% | – |
| TWST | New | TWIST BIOSCIENCE CORP | $3,216,000 | – | 110,856 | – | 0.07% | – |
| VERU | New | VERU INC | $3,078,000 | – | 1,445,000 | – | 0.07% | – |
| ACST | New | ACASTI PHARMA INCcl a new | $2,029,000 | – | 1,779,882 | – | 0.05% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $1,482,000 | – | 139,890 | – | 0.03% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $1,493,000 | – | 2,666,190 | – | 0.03% | – |
| CRY | New | CRYOLIFE INC | $1,497,000 | – | 50,000 | – | 0.03% | – |
| AXSM | New | AXSOME THERAPEUTICS INC | $1,387,000 | – | 53,879 | – | 0.03% | – |
| RACE | New | FERRARI N.V. | $1,001,000 | – | 6,200 | – | 0.02% | – |
| VYGR | New | VOYAGER THERAPEUTICS INC | $996,000 | – | 36,573 | – | 0.02% | – |
| MDCO | New | MEDICINES CO | $712,000 | – | 19,532 | – | 0.02% | – |
| ABEOW | New | ABEONA THERAPEUTICS INC*w exp 12/24/201 | $620,000 | – | 659,636 | – | 0.01% | – |
| FLDM | New | FLUIDIGM CORP | $567,000 | – | 46,030 | – | 0.01% | – |
| GH | New | GUARDANT HEALTH INC | $571,000 | – | 6,617 | – | 0.01% | – |
| ZIOP | New | ZIOPHARM ONCOLOGY INC | $528,000 | – | 90,498 | – | 0.01% | – |
| ALNA | New | ALLENA PHARMACEUTICALS INC | $538,000 | – | 132,300 | – | 0.01% | – |
| MREO | New | MEREO BIOPHARMA GROUP PLCads | $452,000 | – | 179,419 | – | 0.01% | – |
| New | CONFORMIS INC | $436,000 | – | 100,000 | – | 0.01% | – | |
| TNDM | New | TANDEM DIABETES CARE INC | $414,000 | – | 6,422 | – | 0.01% | – |
| NTRA | New | NATERA INC | $401,000 | – | 14,549 | – | 0.01% | – |
| XBI | New | SPDR SERIES TRUSTput | $70,000 | – | 200,000 | – | 0.00% | – |
| OTLKW | New | OUTLOOK THERAPEUTICS INC*w exp 02/18/202 | $46,000 | – | 420,875 | – | 0.00% | – |
| BIIB | New | BIOGEN INCcall | $65,000 | – | 200,000 | – | 0.00% | – |
| SLDB | New | SOLID BIOSCIENCES INCcall | $23,000 | – | 200 | – | 0.00% | – |
Q4 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| GERN | Exit | GERON CORPcall | $0 | – | -200,000 | – | 0.00% | – |
| CAPR | Exit | CAPRICOR THERAPEUTICS INC | $0 | – | -4,000 | – | 0.00% | – |
| ONSIW | Exit | ONCOBIOLOGICS INC*w exp 02/18/201 | $0 | – | -420,875 | – | 0.00% | – |
| Exit | SOLID BIOSCIENCES INCcall | $0 | – | -1,835 | – | -0.00% | – | |
| ONCS | Exit | ONCOSEC MED INC | $0 | – | -50,000 | – | -0.00% | – |
| CASI | Exit | CASI PHARMACEUTICALS INC | $0 | – | -43,682 | – | -0.01% | – |
| HCM | Exit | HUTCHISON CHINA MEDITECH LTDsponsored adr | $0 | – | -10,000 | – | -0.01% | – |
| VCEL | Exit | VERICEL CORP | $0 | – | -27,211 | – | -0.01% | – |
| VCNX | Exit | VACCINEX INC | $0 | – | -50,000 | – | -0.01% | – |
| Exit | PERNIX THERAPEUTICS HLDGS INdbcv 4.250% 4/0 | $0 | – | -1,000,000 | – | -0.01% | – | |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -21,335 | – | -0.01% | – |
| ADMP | Exit | ADAMIS PHARMACEUTICALS CORP | $0 | – | -137,500 | – | -0.01% | – |
| PRTO | Exit | PROTEON THERAPEUTICS INC | $0 | – | -240,488 | – | -0.01% | – |
| MDGL | Exit | MADRIGAL PHARMACEUTICALS INC | $0 | – | -2,213 | – | -0.01% | – |
| BLFS | Exit | BIOLIFE SOLUTIONS INC | $0 | – | -29,376 | – | -0.01% | – |
| NTRA | Exit | NATERA INC | $0 | – | -24,000 | – | -0.02% | – |
| SENS | Exit | SENSEONICS HLDGS INC | $0 | – | -115,000 | – | -0.02% | – |
| MNTA | Exit | MOMENTA PHARMACEUTICALS INC | $0 | – | -24,489 | – | -0.02% | – |
| HSGX | Exit | HISTOGENICS CORP | $0 | – | -1,203,399 | – | -0.02% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS IN | $0 | – | -5,627 | – | -0.02% | – |
| GTHX | Exit | G1 THERAPEUTICS INC | $0 | – | -14,055 | – | -0.02% | – |
| RETA | Exit | REATA PHARMACEUTICALS INC | $0 | – | -9,677 | – | -0.02% | – |
| RACE | Exit | FERRARI N.V. | $0 | – | -6,200 | – | -0.02% | – |
| PTCT | Exit | PTC THERAPEUTICS INC | $0 | – | -19,367 | – | -0.02% | – |
| CSU | Exit | CAPITAL SR LIVING CORP | $0 | – | -100,173 | – | -0.02% | – |
| ALQA | Exit | ALLIQUA BIOMEDICAL INC | $0 | – | -423,394 | – | -0.03% | – |
| BGNE | Exit | BEIGENE LTDsponsored adr | $0 | – | -5,700 | – | -0.03% | – |
| FCAU | Exit | FIAT CHRYSLER AUTOMOBILES N. | $0 | – | -62,000 | – | -0.03% | – |
| VKTX | Exit | VIKING THERAPEUTICS INC | $0 | – | -64,261 | – | -0.03% | – |
| TRHC | Exit | TABULA RASA HEALTHCARE INC | $0 | – | -14,663 | – | -0.03% | – |
| KNSA | Exit | KINIKSA PHARMACEUTICALS LTD | $0 | – | -53,169 | – | -0.04% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC REGISTERED SHS | $0 | – | -157,679 | – | -0.05% | – |
| ODT | Exit | ODONATE THERAPEUTICS INC | $0 | – | -100,000 | – | -0.05% | – |
| VERU | Exit | VERU INC | $0 | – | -1,425,000 | – | -0.05% | – |
| ARVN | Exit | ARVINAS INC | $0 | – | -125,000 | – | -0.06% | – |
| ALNA | Exit | ALLENA PHARMACEUTICALS INC | $0 | – | -250,000 | – | -0.07% | – |
| IVC | Exit | INVACARE CORP | $0 | – | -200,000 | – | -0.08% | – |
| NVTRQ | Exit | NUVECTRA CORP | $0 | – | -135,000 | – | -0.08% | – |
| ABEO | Exit | ABEONA THERAPEUTICS INC | $0 | – | -240,459 | – | -0.08% | – |
| EVH | Exit | EVOLENT HEALTH INCcl a | $0 | – | -110,000 | – | -0.08% | – |
| XERS | Exit | XERIS PHARMACEUTICALS INC | $0 | – | -200,627 | – | -0.09% | – |
| ACHN | Exit | ACHILLION PHARMACEUTICALS IN | $0 | – | -1,000,000 | – | -0.10% | – |
| GERN | Exit | GERON CORPput | $0 | – | -1,950,000 | – | -0.10% | – |
| STIM | Exit | NEURONETICS INC | $0 | – | -135,500 | – | -0.12% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -150,000 | – | -0.12% | – |
| TBIO | Exit | TRANSLATE BIO INC | $0 | – | -500,000 | – | -0.13% | – |
| ABEOW | Exit | ABEONA THERAPEUTICS INCw exp 12/24/201 | $0 | – | -659,636 | – | -0.14% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -3,200,000 | – | -0.14% | – |
| UROV | Exit | UROVANT SCIENCES LTD | $0 | – | -462,659 | – | -0.15% | – |
| OMED | Exit | ONCOMED PHARMACEUTICALS INC | $0 | – | -2,620,897 | – | -0.15% | – |
| EHTH | Exit | EHEALTH INC | $0 | – | -226,220 | – | -0.17% | – |
| PTE | Exit | POLARITYTE INC | $0 | – | -336,818 | – | -0.17% | – |
| EIDX | Exit | EIDOS THERAPEUTICS INC | $0 | – | -686,922 | – | -0.18% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS INC | $0 | – | -365,445 | – | -0.19% | – |
| CDNA | Exit | CAREDX INC | $0 | – | -260,676 | – | -0.20% | – |
| TSRO | Exit | TESARO INC | $0 | – | -200,000 | – | -0.21% | – |
| Exit | ANI PHARMACEUTICALS INCnote 3.000%12/0 | $0 | – | -7,500,000 | – | -0.21% | – | |
| ADMS | Exit | ADAMAS PHARMACEUTICALS INC | $0 | – | -422,015 | – | -0.23% | – |
| MRNS | Exit | MARINUS PHARMACEUTICALS INC | $0 | – | -907,732 | – | -0.24% | – |
| TXMD | Exit | THERAPEUTICSMD INC | $0 | – | -1,500,000 | – | -0.26% | – |
| AMRN | Exit | AMARIN CORP PLCspons adr new | $0 | – | -610,200 | – | -0.26% | – |
| MTEM | Exit | MOLECULAR TEMPLATES INC | $0 | – | -1,974,133 | – | -0.28% | – |
| ABMD | Exit | ABIOMED INC | $0 | – | -23,800 | – | -0.29% | – |
| Exit | PROTAGONIST THERAPEUTICS INC | $0 | – | -1,066,415 | – | -0.29% | – | |
| WVE | Exit | WAVE LIFE SCIENCES LTD | $0 | – | -234,019 | – | -0.31% | – |
| HUM | Exit | HUMANA INC | $0 | – | -35,000 | – | -0.32% | – |
| SYBX | Exit | SYNLOGIC INC | $0 | – | -942,852 | – | -0.36% | – |
| LIVN | Exit | LIVANOVA PLC | $0 | – | -111,000 | – | -0.37% | – |
| MOTS | Exit | MOTUS GI HOLDINGS INC REGISTERED SHS | $0 | – | -2,810,542 | – | -0.38% | – |
| PRQR | Exit | PROQR THERAPEUTICS N.V. | $0 | – | -761,000 | – | -0.39% | – |
| ESTA | Exit | ESTABLISHMENT LABS HLDGS INC | $0 | – | -635,000 | – | -0.41% | – |
| IRTC | Exit | IRHYTHM TECHNOLOGIES INC | $0 | – | -168,939 | – | -0.43% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -1,123,890 | – | -0.45% | – |
| FOMX | Exit | FOAMIX PHARMACEUTICALS LTD | $0 | – | -3,107,424 | – | -0.48% | – |
| RYTM | Exit | RHYTHM PHARMACEUTICALS INC | $0 | – | -664,186 | – | -0.52% | – |
| AQST | Exit | AQUESTIVE THERAPEUTICS INC | $0 | – | -1,150,000 | – | -0.54% | – |
| AKBA | Exit | AKEBIA THERAPEUTICS INC | $0 | – | -2,449,521 | – | -0.58% | – |
| VBIV | Exit | VBI VACCINES INC REGISTERED SHS | $0 | – | -9,665,843 | – | -0.62% | – |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -2,742,821 | – | -0.81% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -1,861,100 | – | -0.83% | – |
| XNCR | Exit | XENCOR INC | $0 | – | -828,095 | – | -0.86% | – |
| NEPT | Exit | NEPTUNE WELLNESS SOLUTIONS I | $0 | – | -8,891,452 | – | -0.92% | – |
| VRAY | Exit | VIEWRAY INC REGISTERED SHS | $0 | – | -3,700,000 | – | -0.93% | – |
| QURE | Exit | UNIQURE NV | $0 | – | -972,831 | – | -0.95% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -470,672 | – | -0.95% | – |
| BHVN | Exit | BIOHAVEN PHARMACEUTICAL HLDG CO L | $0 | – | -990,943 | – | -1.00% | – |
| ADMA | Exit | ADMA BIOLOGICS INC | $0 | – | -6,521,102 | – | -1.08% | – |
| ISRG | Exit | INTUITIVE SURGICAL INC | $0 | – | -72,500 | – | -1.11% | – |
| ARGX | Exit | ARGENX SEsponsored adr | $0 | – | -560,941 | – | -1.14% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INC | $0 | – | -3,085,458 | – | -1.14% | – |
| ECYT | Exit | ENDOCYTE INC REGISTERED SHS | $0 | – | -2,441,700 | – | -1.16% | – |
| KDMN | Exit | KADMON HLDGS INC | $0 | – | -13,165,746 | – | -1.18% | – |
| ATNX | Exit | ATHENEX INC | $0 | – | -2,869,528 | – | -1.19% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -2,661,715 | – | -1.32% | – |
| VRCA | Exit | VERRICA PHARMACEUTICALS INC | $0 | – | -3,410,412 | – | -1.48% | – |
| ALBO | Exit | ALBIREO PHARMA INC | $0 | – | -1,704,330 | – | -1.50% | – |
| RTRX | Exit | RETROPHIN INC | $0 | – | -3,212,871 | – | -1.62% | – |
| CORI | Exit | CORIUM INTERNATIONAL INC | $0 | – | -6,357,133 | – | -1.62% | – |
| MMSI | Exit | MERIT MED SYS INC | $0 | – | -994,198 | – | -1.63% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INC | $0 | – | -1,366,978 | – | -1.68% | – |
| MGTX | Exit | MEIRAGTX HOLDINGS PLC | $0 | – | -4,703,398 | – | -1.71% | – |
| DOVA | Exit | DOVA PHARMACEUTICALS INC | $0 | – | -3,125,851 | – | -1.75% | – |
| QTNT | Exit | QUOTIENT LTD | $0 | – | -8,789,054 | – | -1.77% | – |
| DBVT | Exit | DBV TECHNOLOGIES S Asponsored adr | $0 | – | -3,009,998 | – | -1.81% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -1,089,169 | – | -1.90% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -941,147 | – | -1.96% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS INC | $0 | – | -2,587,953 | – | -1.98% | – |
| ASND | Exit | ASCENDIS PHARMA A Ssponsored adr | $0 | – | -1,072,647 | – | -2.03% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -7,290,199 | – | -2.19% | – |
| LJPC | Exit | LA JOLLA PHARMACEUTICAL CO | $0 | – | -4,313,611 | – | -2.32% | – |
| XLRN | Exit | ACCELERON PHARMA INC | $0 | – | -1,528,205 | – | -2.34% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -1,197,994 | – | -2.80% | – |
| Exit | SOLID BIOSCIENCES INC | $0 | – | -3,927,222 | – | -4.95% | – | |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -3,807,632 | – | -5.05% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -5,148,910 | – | -5.23% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -20,694,424 | – | -6.69% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -4,777,254 | – | -15.71% | – |
Q3 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $587,363,000 | +26.8% | 4,777,254 | +1.3% | 15.71% | +29.3% |
| FOLD | Buy | AMICUS THERAPEUTICS INC | $250,196,000 | -20.0% | 20,694,424 | +3.3% | 6.69% | -18.4% |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS IN | $195,658,000 | -10.4% | 5,148,910 | +6.6% | 5.23% | -8.6% |
| ZGNX | Sell | ZOGENIX INC | $188,858,000 | +7.6% | 3,807,632 | -4.1% | 5.05% | +9.8% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $104,848,000 | -42.4% | 1,197,994 | -35.1% | 2.80% | -41.2% |
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS INC | $82,014,000 | +9.5% | 7,290,199 | +24.6% | 2.19% | +11.7% |
| CRNX | New | CRINETICS PHARMACEUTICALS INC | $74,144,000 | – | 2,587,953 | – | 1.98% | – |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $73,466,000 | +20.4% | 941,147 | -2.1% | 1.96% | +22.8% |
| DBVT | Buy | DBV TECHNOLOGIES S Asponsored adr | $67,604,000 | +66.2% | 3,009,998 | +42.8% | 1.81% | +69.6% |
| QTNT | Buy | QUOTIENT LTD | $66,357,000 | +27.5% | 8,789,054 | +35.6% | 1.77% | +30.0% |
| ARNA | Buy | ARENA PHARMACEUTICALS INC | $62,908,000 | +71.4% | 1,366,978 | +62.4% | 1.68% | +74.8% |
| MMSI | Sell | MERIT MED SYS INC | $61,093,000 | +10.3% | 994,198 | -8.1% | 1.63% | +12.5% |
| CTMX | Buy | CYTOMX THERAPEUTICS INC | $49,242,000 | +12.1% | 2,661,715 | +38.5% | 1.32% | +14.3% |
| ATNX | Buy | ATHENEX INC | $44,592,000 | +1157.9% | 2,869,528 | +1410.3% | 1.19% | +1181.7% |
| ECYT | Buy | ENDOCYTE INC REGISTERED SHS | $43,365,000 | +63.5% | 2,441,700 | +27.1% | 1.16% | +66.9% |
| ARGX | Buy | ARGENX SEsponsored adr | $42,541,000 | -3.0% | 560,941 | +5.9% | 1.14% | -1.0% |
| ISRG | Sell | INTUITIVE SURGICAL INC | $41,615,000 | -13.0% | 72,500 | -27.5% | 1.11% | -11.2% |
| BHVN | Sell | BIOHAVEN PHARMACEUTICAL HLDG CO L | $37,210,000 | -65.7% | 990,943 | -63.9% | 1.00% | -65.0% |
| RGNX | Sell | REGENXBIO INC | $35,536,000 | -42.9% | 470,672 | -45.7% | 0.95% | -41.8% |
| QURE | Sell | UNIQURE NV | $35,402,000 | -35.2% | 972,831 | -32.7% | 0.95% | -33.9% |
| VRAY | Buy | VIEWRAY INC REGISTERED SHS | $34,632,000 | +6572.8% | 3,700,000 | +4833.3% | 0.93% | +6514.3% |
| NEPT | New | NEPTUNE WELLNESS SOLUTIONS I | $34,498,000 | – | 8,891,452 | – | 0.92% | – |
| XNCR | Sell | XENCOR INC | $32,271,000 | -18.4% | 828,095 | -22.5% | 0.86% | -16.7% |
| NVTA | Sell | INVITAE CORP | $31,136,000 | +109.6% | 1,861,100 | -7.9% | 0.83% | +114.1% |
| AKBA | Buy | AKEBIA THERAPEUTICS INC | $21,629,000 | -2.2% | 2,449,521 | +10.6% | 0.58% | -0.3% |
| AQST | New | AQUESTIVE THERAPEUTICS INC | $20,137,000 | – | 1,150,000 | – | 0.54% | – |
| RYTM | Sell | RHYTHM PHARMACEUTICALS INC | $19,374,000 | -22.6% | 664,186 | -17.0% | 0.52% | -21.0% |
| FOMX | Buy | FOAMIX PHARMACEUTICALS LTD | $17,806,000 | +218.1% | 3,107,424 | +178.1% | 0.48% | +223.8% |
| IRTC | Sell | IRHYTHM TECHNOLOGIES INC | $15,992,000 | -36.0% | 168,939 | -45.2% | 0.43% | -34.7% |
| ESTA | New | ESTABLISHMENT LABS HLDGS INC | $15,304,000 | – | 635,000 | – | 0.41% | – |
| PRQR | New | PROQR THERAPEUTICS N.V. | $14,725,000 | – | 761,000 | – | 0.39% | – |
| LIVN | New | LIVANOVA PLC | $13,761,000 | – | 111,000 | – | 0.37% | – |
| HUM | Sell | HUMANA INC | $11,848,000 | -73.1% | 35,000 | -76.4% | 0.32% | -72.6% |
| WVE | Sell | WAVE LIFE SCIENCES LTD | $11,700,000 | +8.2% | 234,019 | -17.2% | 0.31% | +10.2% |
| New | PROTAGONIST THERAPEUTICS INC | $10,973,000 | – | 1,066,415 | – | 0.29% | – | |
| ABMD | Sell | ABIOMED INC | $10,704,000 | -28.6% | 23,800 | -35.1% | 0.29% | -27.2% |
| MTEM | Buy | MOLECULAR TEMPLATES INC | $10,641,000 | +181.0% | 1,974,133 | +172.6% | 0.28% | +187.9% |
| AMRN | New | AMARIN CORP PLCspons adr new | $9,928,000 | – | 610,200 | – | 0.26% | – |
| TXMD | New | THERAPEUTICSMD INC | $9,840,000 | – | 1,500,000 | – | 0.26% | – |
| ADMS | Sell | ADAMAS PHARMACEUTICALS INC | $8,449,000 | -69.8% | 422,015 | -61.1% | 0.23% | -69.2% |
| TSRO | Buy | TESARO INC | $7,802,000 | +75.4% | 200,000 | +100.0% | 0.21% | +78.6% |
| CDNA | Sell | CAREDX INC | $7,521,000 | +31.4% | 260,676 | -44.3% | 0.20% | +34.0% |
| PTE | New | POLARITYTE INC | $6,433,000 | – | 336,818 | – | 0.17% | – |
| EHTH | New | EHEALTH INC | $6,393,000 | – | 226,220 | – | 0.17% | – |
| UROV | New | UROVANT SCIENCES LTD | $5,552,000 | – | 462,659 | – | 0.15% | – |
| SRRA | Sell | SIERRA ONCOLOGY INC | $5,440,000 | -59.2% | 3,200,000 | -28.9% | 0.14% | -58.5% |
| ABEOW | Sell | ABEONA THERAPEUTICS INCw exp 12/24/201 | $5,145,000 | -59.8% | 659,636 | -47.6% | 0.14% | -58.9% |
| CLVS | New | CLOVIS ONCOLOGY INC | $4,406,000 | – | 150,000 | – | 0.12% | – |
| STIM | Buy | NEURONETICS INC | $4,345,000 | +30.1% | 135,500 | +8.0% | 0.12% | +31.8% |
| GERN | New | GERON CORPput | $3,680,000 | – | 1,950,000 | – | 0.10% | – |
| XERS | Sell | XERIS PHARMACEUTICALS INC | $3,527,000 | -58.7% | 200,627 | -55.4% | 0.09% | -58.0% |
| EVH | Buy | EVOLENT HEALTH INCcl a | $3,124,000 | +111.9% | 110,000 | +57.1% | 0.08% | +115.4% |
| ABEO | Buy | ABEONA THERAPEUTICS INC | $3,078,000 | +222.6% | 240,459 | +303.0% | 0.08% | +228.0% |
| NVTRQ | Sell | NUVECTRA CORP | $2,967,000 | -9.4% | 135,000 | -15.3% | 0.08% | -8.1% |
| ARVN | New | ARVINAS INC | $2,109,000 | – | 125,000 | – | 0.06% | – |
| VERU | New | VERU INC | $2,024,000 | – | 1,425,000 | – | 0.05% | – |
| ODT | Sell | ODONATE THERAPEUTICS INC | $1,941,000 | -41.4% | 100,000 | -33.3% | 0.05% | -40.2% |
| KNSA | Sell | KINIKSA PHARMACEUTICALS LTD | $1,356,000 | -29.7% | 53,169 | -52.1% | 0.04% | -29.4% |
| VKTX | New | VIKING THERAPEUTICS INC | $1,119,000 | – | 64,261 | – | 0.03% | – |
| RETA | New | REATA PHARMACEUTICALS INC | $791,000 | – | 9,677 | – | 0.02% | – |
| ICPT | New | INTERCEPT PHARMACEUTICALS IN | $711,000 | – | 5,627 | – | 0.02% | – |
| HSGX | Sell | HISTOGENICS CORP | $656,000 | -88.1% | 1,203,399 | -45.4% | 0.02% | -87.5% |
| NTRA | New | NATERA INC | $575,000 | – | 24,000 | – | 0.02% | – |
| BLFS | New | BIOLIFE SOLUTIONS INC | $514,000 | – | 29,376 | – | 0.01% | – |
| MDGL | Sell | MADRIGAL PHARMACEUTICALS INC | $474,000 | -94.7% | 2,213 | -93.1% | 0.01% | -94.5% |
| PRTO | Sell | PROTEON THERAPEUTICS INC | $469,000 | -42.7% | 240,488 | -28.0% | 0.01% | -38.1% |
| ADMP | New | ADAMIS PHARMACEUTICALS CORP | $481,000 | – | 137,500 | – | 0.01% | – |
| IMMU | New | IMMUNOMEDICS INC | $444,000 | – | 21,335 | – | 0.01% | – |
| VCNX | New | VACCINEX INC | $365,000 | – | 50,000 | – | 0.01% | – |
| New | SOLID BIOSCIENCES INCcall | $40,000 | – | 1,835 | – | 0.00% | – | |
| ONSIW | New | ONCOBIOLOGICS INC*w exp 02/18/201 | $6,000 | – | 420,875 | – | 0.00% | – |
| GERN | New | GERON CORPcall | $10,000 | – | 200,000 | – | 0.00% | – |
| ELOX | Exit | ELLOX PHARMACEUTICALS INC | $0 | – | -2,961 | – | -0.00% | – |
| ACST | Exit | ACASTI PHARMA INCcl a new | $0 | – | -206,677 | – | -0.00% | – |
| TGTX | Exit | TG THERAPEUTICS INC | $0 | – | -100,000 | – | -0.01% | – |
| AGLE | Exit | AEGLEA BIOTHERAPEUTICS INC | $0 | – | -25,694 | – | -0.01% | – |
| NKTR | Exit | NEKTAR THERAPEUTICS | $0 | – | -6,057 | – | -0.01% | – |
| VRNA | Exit | VERONA PHARMA PLCsponsored adr | $0 | – | -22,327 | – | -0.01% | – |
| SGMO | Exit | SANGAMO THERAPEUTICS INC | $0 | – | -25,000 | – | -0.01% | – |
| VTL | Exit | VITAL THERAPIES INC | $0 | – | -150,000 | – | -0.01% | – |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -80,845 | – | -0.01% | – |
| ADAP | Exit | ADAPTIMMUNE THERAPEUTICS PLCsponds adr | $0 | – | -49,302 | – | -0.02% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -24,213 | – | -0.02% | – |
| LOXO | Exit | LOXO ONCOLOGY INC | $0 | – | -3,765 | – | -0.02% | – |
| ARRY | Exit | ARRAY BIOPHARMA INC | $0 | – | -40,133 | – | -0.02% | – |
| AZRX | Exit | AZURRX BIOPHARMA INC | $0 | – | -227,272 | – | -0.02% | – |
| VICL | Exit | VICAL INC | $0 | – | -1,142,858 | – | -0.03% | – |
| SBBP | Exit | STRONGBRIDGE BIOPHARMA PLC | $0 | – | -275,000 | – | -0.04% | – |
| AGRX | Exit | AGILE THERAPEUTICS INC | $0 | – | -3,530,000 | – | -0.05% | – |
| Exit | CHAMPIONS ONCOLOGY INC | $0 | – | -366,972 | – | -0.06% | – | |
| GERN | Exit | GERON CORP | $0 | – | -2,550,000 | – | -0.08% | – |
| AVEO | Exit | AVEO PHARMACEUTICALS INC | $0 | – | -1,891,192 | – | -0.11% | – |
| ASMB | Exit | ASSEMBLY BIOSCIENCES INC | $0 | – | -150,695 | – | -0.16% | – |
| CLSD | Exit | CLEARSIDE BIOMEDICAL INC | $0 | – | -707,581 | – | -0.20% | – |
| FLXN | Exit | FLEXION THERAPEUTICS INC | $0 | – | -307,989 | – | -0.21% | – |
| AXGN | Exit | AXOGEN INC | $0 | – | -165,000 | – | -0.22% | – |
| MNLO | Exit | MENLO THERAPEUTICS INC | $0 | – | -1,241,287 | – | -0.26% | – |
| TDOC | Exit | TELADOC INC | $0 | – | -195,000 | – | -0.30% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -75,898 | – | -0.34% | – |
| GLPG | Exit | GALAPAGOS NVspon adr | $0 | – | -150,875 | – | -0.36% | – |
| NEPT | Exit | NEPTUNE TECHNOLOGIES AND BIORESO | $0 | – | -8,574,015 | – | -0.53% | – |
| GTXI | Exit | GTX INC DEL | $0 | – | -1,501,501 | – | -0.60% | – |
| ATHN | Exit | ATHENAHEALTH INC | $0 | – | -150,000 | – | -0.63% | – |
| BOLD | Exit | AUDENTES THERAPEUTICS INC | $0 | – | -660,406 | – | -0.66% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INC | $0 | – | -564,579 | – | -0.72% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -713,191 | – | -0.92% | – |
| ALXN | Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -463,450 | – | -1.51% | – |
Q2 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $463,226,000 | – | 4,715,250 | – | 12.14% | – |
| FOLD | New | AMICUS THERAPEUTICS INC | $312,782,000 | – | 20,024,424 | – | 8.20% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $218,266,000 | – | 4,828,910 | – | 5.72% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $181,902,000 | – | 1,846,911 | – | 4.77% | – |
| ZGNX | New | ZOGENIX INC | $175,489,000 | – | 3,970,357 | – | 4.60% | – |
| New | SOLID BIOSCIENCES INC | $139,927,000 | – | 3,927,222 | – | 3.67% | – | |
| LJPC | New | LA JOLLA PHARMACEUTICAL CO | $125,828,000 | – | 4,313,611 | – | 3.30% | – |
| BHVN | New | BIOHAVEN PHARMACEUTICAL HOLDING CO L | $108,429,000 | – | 2,743,647 | – | 2.84% | – |
| DOVA | New | DOVA PHARMACEUTICALS INC | $93,525,000 | – | 3,125,851 | – | 2.45% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $74,908,000 | – | 5,852,202 | – | 1.96% | – |
| XLRN | New | ACCELERON PHARMA INC | $74,149,000 | – | 1,528,205 | – | 1.94% | – |
| ASND | New | ASCENDIS PHARMA A Ssponsored adr | $71,352,000 | – | 1,072,647 | – | 1.87% | – |
| VRCA | New | VERRICA PHARMACEUTICALS INC | $67,287,000 | – | 3,410,412 | – | 1.76% | – |
| RGNX | New | REGENXBIO INC | $62,215,000 | – | 867,106 | – | 1.63% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $61,014,000 | – | 961,147 | – | 1.60% | – |
| ALBO | New | ALBIREO PHARMA INC | $60,504,000 | – | 1,704,330 | – | 1.59% | – |
| ALXN | New | ALEXION PHARMACEUTICALS INC | $57,537,000 | – | 463,450 | – | 1.51% | – |
| RTRX | New | RETROPHIN INC | $57,387,000 | – | 3,212,871 | – | 1.50% | – |
| MMSI | New | MERIT MED SYS INC | $55,399,000 | – | 1,082,013 | – | 1.45% | – |
| QURE | New | UNIQURE NV | $54,607,000 | – | 1,444,628 | – | 1.43% | – |
| MYOK | New | MYOKARDIA INC | $54,078,000 | – | 1,089,169 | – | 1.42% | – |
| MGTX | New | MEIRAGTX HOLDINGS PLC | $53,900,000 | – | 4,703,398 | – | 1.41% | – |
| KDMN | New | KADMON HLDGS INC | $52,531,000 | – | 13,165,746 | – | 1.38% | – |
| QTNT | New | QUOTIENT LTD | $52,058,000 | – | 6,483,020 | – | 1.36% | – |
| CORI | New | CORIUM INTERNATIONAL INC | $50,921,000 | – | 6,357,133 | – | 1.34% | – |
| ISRG | New | INTUITIVE SURGICAL INC | $47,848,000 | – | 100,000 | – | 1.25% | – |
| HUM | New | HUMANA INC | $44,114,000 | – | 148,218 | – | 1.16% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $43,930,000 | – | 1,921,715 | – | 1.15% | – |
| ARGX | New | ARGENX SE ADRadr | $43,879,000 | – | 529,560 | – | 1.15% | – |
| DBVT | New | DBV TECHNOLOGIES SA SHS SPONSORED AMERICAN DEPOSITadr | $40,667,000 | – | 2,108,198 | – | 1.07% | – |
| XNCR | New | XENCOR INC | $39,530,000 | – | 1,068,095 | – | 1.04% | – |
| CBAY | New | CYMABAY THERAPEUTICS INC | $36,808,000 | – | 2,742,821 | – | 0.96% | – |
| ARNA | New | ARENA PHARMACEUTICALS INC | $36,710,000 | – | 841,978 | – | 0.96% | – |
| MRTX | New | MIRATI THERAPEUTICS INC | $35,160,000 | – | 713,191 | – | 0.92% | – |
| ADMA | New | ADMA BIOLOGICS INC | $29,410,000 | – | 6,521,102 | – | 0.77% | – |
| ADMS | New | ADAMAS PHARMACEUTICALS INC | $28,004,000 | – | 1,084,159 | – | 0.73% | – |
| PBYI | New | PUMA BIOTECHNOLOGY INC | $27,667,000 | – | 564,579 | – | 0.72% | – |
| VBIV | New | VBI VACCINES INC | $26,581,000 | – | 9,665,843 | – | 0.70% | – |
| ECYT | New | ENDOCYTE INC | $26,519,000 | – | 1,921,700 | – | 0.70% | – |
| BOLD | New | AUDENTES THERAPEUTICS INC | $25,234,000 | – | 660,406 | – | 0.66% | – |
| RYTM | New | RHYTHM PHARMACEUTICALS INC | $25,029,000 | – | 800,686 | – | 0.66% | – |
| IRTC | New | IRHYTHM TECHNOLOGIES INC | $24,989,000 | – | 308,006 | – | 0.66% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $24,529,000 | – | 3,085,458 | – | 0.64% | – |
| ATHN | New | ATHENAHEALTH INC | $23,871,000 | – | 150,000 | – | 0.63% | – |
| GTXI | New | GTX INC DEL | $22,988,000 | – | 1,501,501 | – | 0.60% | – |
| AKBA | New | AKEBIA THERAPEUTICS INC | $22,110,000 | – | 2,215,400 | – | 0.58% | – |
| NEPT | New | NEPTUNE TECHNOLOGIES AND BIORESO | $20,379,000 | – | 8,574,015 | – | 0.53% | – |
| MOTS | New | MOTUS GI HLDGS INC | $20,207,000 | – | 2,810,542 | – | 0.53% | – |
| ZYME | New | ZYMEWORKS INC | $15,920,000 | – | 1,123,890 | – | 0.42% | – |
| ABMD | New | ABIOMED INC | $14,990,000 | – | 36,646 | – | 0.39% | – |
| NVTA | New | INVITAE CORP | $14,855,000 | – | 2,021,100 | – | 0.39% | – |
| EIDX | New | EIDOS THERAPEUTICS INC | $13,971,000 | – | 686,922 | – | 0.37% | – |
| GLPG | New | GALAPAGOS NVspon adr | $13,908,000 | – | 150,875 | – | 0.36% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $13,320,000 | – | 4,500,000 | – | 0.35% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $12,900,000 | – | 75,898 | – | 0.34% | – |
| ABEOW | New | ABEONA THERAPEUTICS INCw exp 12/24/201 | $12,810,000 | – | 1,259,636 | – | 0.34% | – |
| TDOC | New | TELADOC INC | $11,320,000 | – | 195,000 | – | 0.30% | – |
| WVE | New | WAVE LIFE SCIENCES LTD | $10,817,000 | – | 282,798 | – | 0.28% | – |
| MNLO | New | MENLO THERAPEUTICS INC | $10,079,000 | – | 1,241,287 | – | 0.26% | – |
| SYBX | New | SYNLOGIC INC | $9,268,000 | – | 942,852 | – | 0.24% | – |
| MDGL | New | MADRIGAL PHARMACEUTICALS INC | $9,010,000 | – | 32,213 | – | 0.24% | – |
| XERS | New | XERIS PHARMACEUTICALS INC | $8,541,000 | – | 450,000 | – | 0.22% | – |
| New | ANI PHARMACEUTICALS INCnote 3.005 12/0 | $8,458,000 | – | 7,500,000 | – | 0.22% | – | |
| AXGN | New | AXOGEN INC | $8,291,000 | – | 165,000 | – | 0.22% | – |
| FLXN | New | FLEXION THERAPEUTICS INC | $7,962,000 | – | 307,989 | – | 0.21% | – |
| CLSD | New | CLEARSIDE BIOMEDICAL INC | $7,599,000 | – | 707,581 | – | 0.20% | – |
| MRNS | New | MARINUS PHARMACEUTICALS INC | $6,417,000 | – | 907,732 | – | 0.17% | – |
| TBIO | New | TRANSLATE BIO INC | $6,325,000 | – | 500,000 | – | 0.17% | – |
| OMED | New | ONCOMED PHARMACEUTICALS | $6,054,000 | – | 2,620,897 | – | 0.16% | – |
| ASMB | New | ASSEMBLY BIOSCIENCES INC | $5,909,000 | – | 150,695 | – | 0.16% | – |
| CDNA | New | CAREDX INC | $5,724,000 | – | 467,676 | – | 0.15% | – |
| FOMX | New | FOAMIX PHARMACEUTICALS LTD | $5,598,000 | – | 1,117,324 | – | 0.15% | – |
| HSGX | New | HISTOGENICS CORP | $5,508,000 | – | 2,203,277 | – | 0.14% | – |
| ARWR | New | ARROWHEAD PHARMACEUTICALS INC | $4,970,000 | – | 365,445 | – | 0.13% | – |
| TSRO | New | TESARO INC | $4,447,000 | – | 100,000 | – | 0.12% | – |
| AVEO | New | AVEO PHARMACEUTICALS INC | $4,274,000 | – | 1,891,192 | – | 0.11% | – |
| MTEM | New | MOLECULAR TEMPLATES INC | $3,787,000 | – | 724,133 | – | 0.10% | – |
| IVC | New | INVACARE CORP | $3,720,000 | – | 200,000 | – | 0.10% | – |
| ATNX | New | ATHENEX INC | $3,545,000 | – | 190,000 | – | 0.09% | – |
| STIM | New | NEURONETICS INC | $3,340,000 | – | 125,500 | – | 0.09% | – |
| ODT | New | ODONATE THERAPEUTICS INC | $3,312,000 | – | 150,000 | – | 0.09% | – |
| NVTRQ | New | NUVECTRA CORP | $3,274,000 | – | 159,466 | – | 0.09% | – |
| ALNA | New | ALLENA PHARMACEUTICALS INC | $3,258,000 | – | 250,000 | – | 0.08% | – |
| GERN | New | GERON CORP | $2,922,000 | – | 2,550,000 | – | 0.08% | – |
| ACHN | New | ACHILLION PHARMACEUTICALS INC | $2,830,000 | – | 1,000,000 | – | 0.07% | – |
| New | CHAMPIONS ONCOLOGY INC | $2,326,000 | – | 366,972 | – | 0.06% | – | |
| KNSA | New | KINIKSA PHARMACEUTICALS LTD | $1,928,000 | – | 111,111 | – | 0.05% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $1,923,000 | – | 157,679 | – | 0.05% | – |
| AGRX | New | AGILE THERAPEUTICS INC | $1,744,000 | – | 3,530,000 | – | 0.05% | – |
| SBBP | New | STRONGBRIDGE BIOPHARMA PLC | $1,650,000 | – | 275,000 | – | 0.04% | – |
| EVH | New | EVOLENT HEALTH INCcl a | $1,474,000 | – | 70,000 | – | 0.04% | – |
| VICL | New | VICAL INC | $1,314,000 | – | 1,142,858 | – | 0.03% | – |
| FCAU | New | FIAT CHRYSLER AUTOMOBILES N. | $1,171,000 | – | 62,000 | – | 0.03% | – |
| CSU | New | CAPITAL SR LIVING CORP | $1,069,000 | – | 100,173 | – | 0.03% | – |
| TRHC | New | TABULA RASA HEALTHCARE INC | $936,000 | – | 14,663 | – | 0.02% | – |
| ABEO | New | ABEONA THERAPEUTICS INC | $954,000 | – | 59,662 | – | 0.02% | – |
| ALQA | New | ALLIQUA BIOMEDICAL INC | $867,000 | – | 423,394 | – | 0.02% | – |
| BGNE | New | BEIGENE LTDsponsored adr | $876,000 | – | 5,700 | – | 0.02% | – |
| RACE | New | FERRARI N.V. | $837,000 | – | 6,200 | – | 0.02% | – |
| PRTO | New | PROTEON THERAPEUTICS INC | $819,000 | – | 334,116 | – | 0.02% | – |
| AZRX | New | AZURRX BIOPHARMA INC | $730,000 | – | 227,272 | – | 0.02% | – |
| ARRY | New | ARRAY BIOPHARMA INC | $673,000 | – | 40,133 | – | 0.02% | – |
| LOXO | New | LOXO ONCOLOGY INC | $653,000 | – | 3,765 | – | 0.02% | – |
| PTCT | New | PTC THERAPEUTICS INC | $653,000 | – | 19,367 | – | 0.02% | – |
| GTHX | New | G1 THERAPEUTICS INC | $611,000 | – | 14,055 | – | 0.02% | – |
| ADAP | New | ADAPTIMMUNE THERAPEUTICS PLCsponds adr | $585,000 | – | 49,302 | – | 0.02% | – |
| COLL | New | COLLEGIUM PHARMACEUTICAL INC | $577,000 | – | 24,213 | – | 0.02% | – |
| VRAY | New | VIEWRAY INC | $519,000 | – | 75,000 | – | 0.01% | – |
| MNTA | New | MOMENTA PHARMACEUTICALS INC | $501,000 | – | 24,489 | – | 0.01% | – |
| SENS | New | SENSEONICS HLDGS INC | $473,000 | – | 115,000 | – | 0.01% | – |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $428,000 | – | 80,845 | – | 0.01% | – |
| New | PERNIX THERAPEUTICS HLDGS INdbvc 4.250% 4/0 | $426,000 | – | 1,000,000 | – | 0.01% | – | |
| VTL | New | VITAL THERAPIES INC | $405,000 | – | 150,000 | – | 0.01% | – |
| CASI | New | CASI PHARMACEUTICALS INC | $360,000 | – | 43,682 | – | 0.01% | – |
| SGMO | New | SANGAMO THERAPEUTICS INC | $355,000 | – | 25,000 | – | 0.01% | – |
| NKTR | New | NEKTAR THERAPEUTICS | $296,000 | – | 6,057 | – | 0.01% | – |
| HCM | New | HUTCHISON CHINA MEDITECH LTDsponsored adr | $301,000 | – | 10,000 | – | 0.01% | – |
| VRNA | New | VERONA PHARMA PLCsponsored adr | $307,000 | – | 22,327 | – | 0.01% | – |
| TGTX | New | TG THERAPEUTICS INC | $258,000 | – | 100,000 | – | 0.01% | – |
| VCEL | New | VERICEL CORP | $264,000 | – | 27,211 | – | 0.01% | – |
| AGLE | New | AEGLEA BIOTHERAPEUTICS INC | $272,000 | – | 25,694 | – | 0.01% | – |
| ACST | New | ACASTI PHARMA INCcl a new | $117,000 | – | 206,677 | – | 0.00% | – |
| ONCS | New | ONCOSEC MED INC | $69,000 | – | 50,000 | – | 0.00% | – |
| ELOX | New | ELLOX PHARMACEUTICALS INC | $50,000 | – | 2,961 | – | 0.00% | – |
| CAPR | New | CAPRICOR THERAPEUTICS INC | $5,000 | – | 4,000 | – | 0.00% | – |
Q4 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| INCY | Exit | INCYTE CORPcall | $0 | – | -200,000 | – | -0.00% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INCcall | $0 | – | -120,000 | – | -0.00% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INCput | $0 | – | -840,000 | – | -0.00% | – |
| SENS | Exit | SENSEONICS HOLDINGS INC | $0 | – | -100,000 | – | -0.01% | – |
| SAGE | Exit | SAGE THERAPEUTICS INCcall | $0 | – | -430,000 | – | -0.01% | – |
| HCM | Exit | HUTCHISON CHINA MEDITECH LTDsponsored adr | $0 | – | -20,000 | – | -0.01% | – |
| ACST | Exit | ACASTI PHARMA INCcl a new | $0 | – | -373,118 | – | -0.01% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS INcall | $0 | – | -500,000 | – | -0.01% | – |
| MOH | Exit | MOLINA HEALTHCARE INCcall | $0 | – | -100,000 | – | -0.01% | – |
| ZSAN | Exit | ZOSANO PHARMA INC | $0 | – | -1,000,000 | – | -0.02% | – |
| Exit | PERNIX THERAPEUTICS HLDGS INdbcv 4.250% 4/0 | $0 | – | -2,000,000 | – | -0.02% | – | |
| Exit | NABRIVA THERAPEUTICS PLC | $0 | – | -105,140 | – | -0.02% | – | |
| PTLA | Exit | PORTOLA PHARMACEUTICALS INC | $0 | – | -15,740 | – | -0.02% | – |
| AKAOQ | Exit | ACHAOGEN INC | $0 | – | -55,102 | – | -0.02% | – |
| FGEN | Exit | FIBROGEN INC | $0 | – | -17,186 | – | -0.02% | – |
| CUTR | Exit | CUTERA INC | $0 | – | -23,962 | – | -0.02% | – |
| TDOC | Exit | TELADOC INC | $0 | – | -29,282 | – | -0.02% | – |
| PRTK | Exit | PARATEK PHARMACEUTICALS INC | $0 | – | -42,372 | – | -0.02% | – |
| IMGN | Exit | IMMUNOGEN INC | $0 | – | -140,252 | – | -0.02% | – |
| INOV | Exit | INOVALON HLDGS INC | $0 | – | -60,000 | – | -0.02% | – |
| ESPR | Exit | ESPERION THERAPEUTICS INC NE | $0 | – | -21,538 | – | -0.02% | – |
| PRAH | Exit | PRA HEALTH SCIENCES INC | $0 | – | -14,854 | – | -0.02% | – |
| ATRA | Exit | ATARA BIOTHERAPEUTICS INC | $0 | – | -70,212 | – | -0.02% | – |
| KERX | Exit | KERYX BIOPHARMACEUTICALS INC | $0 | – | -166,772 | – | -0.02% | – |
| BGNE | Exit | BEIGENE LTDsponsored adr | $0 | – | -11,400 | – | -0.02% | – |
| HSKA | Exit | HESKA CORP | $0 | – | -14,600 | – | -0.02% | – |
| ALGN | Exit | ALIGN TECHNOLOGY INC | $0 | – | -6,896 | – | -0.02% | – |
| VNDA | Exit | VANDA PHARMACEUTICALS INC | $0 | – | -72,464 | – | -0.02% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -11,238 | – | -0.02% | – |
| PRTO | Exit | PROTEON THERAPEUTICS INC | $0 | – | -668,232 | – | -0.03% | – |
| RACE | Exit | FERRARI N V | $0 | – | -12,400 | – | -0.03% | – |
| VYGR | Exit | VOYAGER THERAPEUTICS INC | $0 | – | -69,208 | – | -0.03% | – |
| CNC | Exit | CENTENE CORP DEL | $0 | – | -15,452 | – | -0.03% | – |
| AZRX | Exit | AZURRX BIOPHARMA INC | $0 | – | -454,544 | – | -0.04% | – |
| LNTH | Exit | LANTHEUS HLDGS INC | $0 | – | -107,526 | – | -0.04% | – |
| FCAU | Exit | FIAT CHRYSLER AUTOMOBILES Nshrs | $0 | – | -124,000 | – | -0.04% | – |
| EXEL | Exit | EXELIXIS INC | $0 | – | -92,722 | – | -0.04% | – |
| OSUR | Exit | ORASURE TECHNOLOGIES INC | $0 | – | -109,458 | – | -0.05% | – |
| ZYNE | Exit | ZYNERBA PHARMACEUTICALS INC | $0 | – | -261,400 | – | -0.05% | – |
| CSBR | Exit | CHAMPIONS ONCOLOGY INC | $0 | – | -773,080 | – | -0.05% | – |
| CRIS | Exit | CURIS INC | $0 | – | -1,902,402 | – | -0.05% | – |
| AFMD | Exit | AFFIMED N V | $0 | – | -1,336,428 | – | -0.06% | – |
| Exit | XENON PHARMACEUTICALS INC | $0 | – | -1,007,706 | – | -0.06% | – | |
| BCLI | Exit | BRAINSTORM CELL THERAPEUTICS | $0 | – | -800,000 | – | -0.06% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -315,358 | – | -0.07% | – |
| DCPH | Exit | DECIPHERA PHARMACEUTICALS IN | $0 | – | -205,000 | – | -0.07% | – |
| ABEO | Exit | ABEONA THERAPEUTICS INC | $0 | – | -233,800 | – | -0.08% | – |
| MCRB | Exit | SERES THERAPEUTICS INC | $0 | – | -270,000 | – | -0.08% | – |
| ADMA | Exit | ADMA BIOLOGICS INC | $0 | – | -1,442,204 | – | -0.08% | – |
| MGCD | Exit | MGC DIAGNOSTICS CORP | $0 | – | -504,654 | – | -0.09% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INCcall | $0 | – | -200,000 | – | -0.09% | – |
| OCRX | Exit | OCERA THERAPEUTICS INC | $0 | – | -4,077,760 | – | -0.09% | – |
| VIVE | Exit | VIVEVE MEDICAL INC | $0 | – | -973,976 | – | -0.10% | – |
| PFNX | Exit | PFENEX INC | $0 | – | -1,691,946 | – | -0.10% | – |
| DBVT | Exit | DBV TECHNOLOGIES S Aput | $0 | – | -1,100,000 | – | -0.11% | – |
| CRBP | Exit | CORBUS PHARMACEUTICALS HLDGS | $0 | – | -829,368 | – | -0.11% | – |
| VRNA | Exit | VERONA PHARMA PLCsponsored adr | $0 | – | -400,000 | – | -0.12% | – |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -80,000 | – | -0.12% | – |
| RGEN | Exit | REPLIGEN INC | $0 | – | -174,800 | – | -0.13% | – |
| HSGX | Exit | HISTOGENICS CORP | $0 | – | -3,555,554 | – | -0.13% | – |
| NCNA | Exit | NUCANA PLSsponsored adr | $0 | – | -400,000 | – | -0.14% | – |
| GWPH | Exit | GW PHARMACEUTICALS PLCads | $0 | – | -73,526 | – | -0.14% | – |
| IVC | Exit | INVACARE CORP | $0 | – | -400,000 | – | -0.15% | – |
| NEPT | Exit | NEPTUNE TECHNOLOGIES BIORESO | $0 | – | -13,039,268 | – | -0.16% | – |
| MTEM | Exit | MOLECULAR TEMPLATES INC | $0 | – | -1,448,266 | – | -0.16% | – |
| MMSI | Exit | MERIT MEDICAL SYS INC | $0 | – | -200,000 | – | -0.16% | – |
| NLNK | Exit | NEWLINK GENETICS CORP | $0 | – | -900,000 | – | -0.18% | – |
| VSAR | Exit | VERSARTIS INC | $0 | – | -3,776,320 | – | -0.18% | – |
| OMED | Exit | ONCOMED PHARMACEUTICALS INC | $0 | – | -2,076,578 | – | -0.18% | – |
| ZLAB | Exit | ZAI LAB LTDadr | $0 | – | -350,000 | – | -0.18% | – |
| CLSD | Exit | CLEARSIDE BIOMEDICAL INC | $0 | – | -1,240,362 | – | -0.20% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS IN | $0 | – | -180,000 | – | -0.20% | – |
| HRTX | Exit | HERON THERAPEUTICS INC | $0 | – | -660,000 | – | -0.20% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -7,310,372 | – | -0.22% | – |
| ACRX | Exit | ACELRX PHARMACEUTICALS INC | $0 | – | -2,489,216 | – | -0.22% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -1,461,536 | – | -0.22% | – |
| FOMX | Exit | FOAMIX PHARMACEUTICALS LTD | $0 | – | -2,234,648 | – | -0.24% | – |
| CMTA | Exit | CLEMENTIA PHARMACEUTICALS IN | $0 | – | -704,500 | – | -0.24% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -270,888 | – | -0.24% | – |
| CSU | Exit | CAPITAL SR LIVING CORP | $0 | – | -1,120,346 | – | -0.27% | – |
| OXFD | Exit | OXFORD IMMUNOTEC GLOBAL PLC | $0 | – | -930,712 | – | -0.30% | – |
| Exit | ANI PHARMACEUTICALSnote 3.00% 12/0 | $0 | – | -15,000,000 | – | -0.31% | – | |
| URGN | Exit | UROGEN PHARMA LTD | $0 | – | -538,028 | – | -0.32% | – |
| MRNS | Exit | MARINUS PHARMACEUTICALS | $0 | – | -2,905,400 | – | -0.33% | – |
| ATHN | Exit | ATHENAHEALTH SHARES | $0 | – | -140,000 | – | -0.33% | – |
| ABMD | Exit | ABIOMED INC | $0 | – | -103,458 | – | -0.33% | – |
| ARDX | Exit | ARDELYX INC | $0 | – | -19,457,672 | – | -0.34% | – |
| QURE | Exit | UNIQURE NV | $0 | – | -2,080,238 | – | -0.38% | – |
| ARGX | Exit | ARGENX SEsponsored adr | $0 | – | -900,000 | – | -0.39% | – |
| BHVN | Exit | BIOHAVEN PHARMACTL HLDG CO L | $0 | – | -612,268 | – | -0.44% | – |
| AVEO | Exit | AVEO PHARMACEUTICALS INC | $0 | – | -6,830,232 | – | -0.48% | – |
| SYBX | Exit | SYNLOGIC INC | $0 | – | -1,372,704 | – | -0.50% | – |
| TFX | Exit | TELEFLEX INC | $0 | – | -110,400 | – | -0.51% | – |
| WVE | Exit | WAVE LIFE SCIENCES LTD | $0 | – | -1,285,596 | – | -0.53% | – |
| ATRS | Exit | ANTARES PHARMA INC | $0 | – | -8,707,794 | – | -0.54% | – |
| ITCI | Exit | INTRA CELLULAR THERAPIES INC | $0 | – | -1,858,920 | – | -0.56% | – |
| EVH | Exit | EVOLENT HEALTH INCcl a | $0 | – | -1,700,000 | – | -0.58% | – |
| ASMB | Exit | ASSEMBLY BIOSCIENCES INC | $0 | – | -883,666 | – | -0.59% | – |
| ALQA | Exit | ALLIQUA BIOMEDICAL INC | $0 | – | -8,467,902 | – | -0.59% | – |
| ABEOW | Exit | ABEONA THERAPEUTICS INC*w exp 12/24/201 | $0 | – | -2,519,272 | – | -0.60% | – |
| ONCE | Exit | SPARK THERAPEUTICS INC | $0 | – | -360,000 | – | -0.61% | – |
| AVDL | Exit | AVADEL PHARMACEUTICALS PLCsponsored adr | $0 | – | -3,098,010 | – | -0.62% | – |
| KDMN | Exit | KADMON HLDGS INC | $0 | – | -10,371,694 | – | -0.66% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -3,769,000 | – | -0.67% | – |
| ALBO | Exit | ALBIREO PHARMA INC | $0 | – | -1,690,000 | – | -0.68% | – |
| QTNT | Exit | QUOTIENT TECHNOLOGY INC | $0 | – | -7,453,972 | – | -0.70% | – |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -4,701,764 | – | -0.72% | – |
| IRTC | Exit | IRHYTHM TECHNOLOGIES INC | $0 | – | -745,342 | – | -0.74% | – |
| GLPG | Exit | GALAPAGOS N Vspon adr | $0 | – | -412,810 | – | -0.80% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -277,252 | – | -0.80% | – |
| SELB | Exit | SELECTA BIOSCIENCES INC | $0 | – | -2,324,650 | – | -0.81% | – |
| BOLD | Exit | AUDENTES THERAPEUTICS INC | $0 | – | -1,562,618 | – | -0.84% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INC | $0 | – | -6,170,916 | – | -0.85% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -1,101,434 | – | -0.90% | – |
| HUM | Exit | HUMANA INC | $0 | – | -200,000 | – | -0.93% | – |
| DBVT | Exit | DBV TECHNOLOGIES S Asponsored adr | $0 | – | -1,152,838 | – | -0.93% | – |
| VBIV | Exit | VBI VACCINES INC | $0 | – | -13,131,686 | – | -0.96% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -2,780,762 | – | -0.96% | – |
| ISRG | Exit | INTUITIVE SURGICAL INC | $0 | – | -50,390 | – | -1.01% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -849,322 | – | -1.13% | – |
| XNCR | Exit | XENCOR INC | $0 | – | -2,586,190 | – | -1.13% | – |
| AKBA | Exit | AKEBIA THERAPEUTICS INC | $0 | – | -3,260,000 | – | -1.22% | – |
| ANAB | Exit | ANAPTYSBIO INC | $0 | – | -1,964,538 | – | -1.31% | – |
| NXTM | Exit | NXSTAGE MEDICAL INC | $0 | – | -2,529,046 | – | -1.33% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -9,452,228 | – | -1.40% | – |
| DOVA | Exit | DOVA PHARMACEUTICALS INC | $0 | – | -3,508,030 | – | -1.63% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -2,882,372 | – | -1.81% | – |
| TSRO | Exit | TESARO INC | $0 | – | -777,302 | – | -1.92% | – |
| XLRN | Exit | ACCELERON PHARMA INC | $0 | – | -3,232,518 | – | -2.30% | – |
| CORI | Exit | CORIUM INTL INC | $0 | – | -11,694,266 | – | -2.47% | – |
| AVXS | Exit | AVEXIS INC | $0 | – | -1,342,362 | – | -2.48% | – |
| RTRX | Exit | RETROPHIN INC | $0 | – | -5,372,408 | – | -2.55% | – |
| LJPC | Exit | LA JOLLA PHARMACEUTICAL CO | $0 | – | -4,314,022 | – | -2.86% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INC | $0 | – | -1,847,640 | – | -4.22% | – |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -7,340,714 | – | -4.91% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -8,528,132 | – | -5.06% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS | $0 | – | -3,577,604 | – | -8.02% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -35,777,194 | – | -10.30% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -9,583,178 | – | -11.21% | – |
Q3 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $587,258,000 | +256.8% | 9,583,178 | +167.9% | 11.21% | +35.4% |
| FOLD | Buy | AMICUS THERAPEUTICS INC | $539,520,000 | +209.8% | 35,777,194 | +106.8% | 10.30% | +17.5% |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS | $420,334,000 | +187.5% | 3,577,604 | +95.2% | 8.02% | +9.1% |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS IN | $264,798,000 | +146.1% | 8,528,132 | +116.8% | 5.06% | -6.6% |
| ZGNX | Buy | ZOGENIX INC | $257,292,000 | +414.6% | 7,340,714 | +112.9% | 4.91% | +95.2% |
| PBYI | Buy | PUMA BIOTECHNOLOGY INC | $221,254,000 | +245.2% | 1,847,640 | +152.0% | 4.22% | +31.0% |
| LJPC | Buy | LA JOLLA PHARMACEUTICAL CO | $150,042,000 | +133.7% | 4,314,022 | +100.0% | 2.86% | -11.3% |
| RTRX | Buy | RETROPHIN INC | $133,718,000 | +158.1% | 5,372,408 | +101.0% | 2.55% | -2.1% |
| AVXS | Buy | AVEXIS INC | $129,846,000 | +482.8% | 1,342,362 | +395.0% | 2.48% | +121.1% |
| CORI | Buy | CORIUM INTL INC | $129,572,000 | +197.0% | 11,694,266 | +100.0% | 2.47% | +12.7% |
| XLRN | Buy | ACCELERON PHARMA INC | $120,638,000 | +458.1% | 3,232,518 | +354.5% | 2.30% | +111.7% |
| TSRO | Buy | TESARO INC | $100,350,000 | +99.6% | 777,302 | +116.2% | 1.92% | -24.3% |
| RGNX | Buy | REGENXBIO INC | $94,974,000 | +250.7% | 2,882,372 | +110.2% | 1.81% | +33.0% |
| DOVA | Buy | DOVA PHARMACEUTICALS INC | $85,174,000 | +123.9% | 3,508,030 | +105.6% | 1.63% | -15.0% |
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS INC | $73,254,000 | +128.4% | 9,452,228 | +116.6% | 1.40% | -13.3% |
| NXTM | Buy | NXSTAGE MEDICAL INC | $69,802,000 | +79.0% | 2,529,046 | +62.6% | 1.33% | -32.1% |
| ANAB | Buy | ANAPTYSBIO INC | $68,660,000 | +201.3% | 1,964,538 | +106.3% | 1.31% | +14.3% |
| AKBA | Buy | AKEBIA THERAPEUTICS INC | $64,124,000 | +305.6% | 3,260,000 | +196.4% | 1.22% | +54.0% |
| XNCR | Buy | XENCOR INC | $59,276,000 | +117.2% | 2,586,190 | +100.0% | 1.13% | -17.6% |
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $59,172,000 | +162.6% | 849,322 | +91.0% | 1.13% | -0.4% |
| ISRG | Buy | INTUITIVE SURGICAL INC | $52,702,000 | +172.3% | 50,390 | +143.5% | 1.01% | +3.3% |
| CTMX | Buy | CYTOMX THERAPEUTICS INC | $50,526,000 | +134.5% | 2,780,762 | +100.0% | 0.96% | -11.0% |
| VBIV | Buy | VBI VACCINES INC | $50,556,000 | +77.0% | 13,131,686 | +100.0% | 0.96% | -32.8% |
| DBVT | Buy | DBV TECHNOLOGIES S Asponsored adr | $48,926,000 | +131.5% | 1,152,838 | +94.8% | 0.93% | -12.1% |
| HUM | Buy | HUMANA INC | $48,726,000 | +159.3% | 200,000 | +156.1% | 0.93% | -1.7% |
| MYOK | Buy | MYOKARDIA INC | $47,196,000 | +225.7% | 1,101,434 | +99.1% | 0.90% | +23.6% |
| ALDX | Buy | ALDEYRA THERAPEUTICS INC | $44,430,000 | +231.1% | 6,170,916 | +113.9% | 0.85% | +25.6% |
| BOLD | Buy | AUDENTES THERAPEUTICS INC | $43,770,000 | +223.4% | 1,562,618 | +120.9% | 0.84% | +22.8% |
| SELB | Buy | SELECTA BIOSCIENCES INC | $42,424,000 | +167.9% | 2,324,650 | +191.6% | 0.81% | +1.6% |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $42,154,000 | +17.9% | 277,252 | -0.0% | 0.80% | -55.3% |
| GLPG | Buy | GALAPAGOS N Vspon adr | $42,004,000 | +142.4% | 412,810 | +82.3% | 0.80% | -8.0% |
| IRTC | Buy | IRHYTHM TECHNOLOGIES INC | $38,670,000 | +221.7% | 745,342 | +163.5% | 0.74% | +22.0% |
| CBAY | New | CYMABAY THERAPEUTICS INC | $37,896,000 | – | 4,701,764 | – | 0.72% | – |
| QTNT | Buy | QUOTIENT TECHNOLOGY INC | $36,748,000 | +41.3% | 7,453,972 | +100.7% | 0.70% | -46.4% |
| ALBO | Buy | ALBIREO PHARMA INC | $35,406,000 | +103.4% | 1,690,000 | +100.0% | 0.68% | -22.8% |
| NVTA | Buy | INVITAE CORP | $35,314,000 | +468.8% | 3,769,000 | +480.3% | 0.67% | +116.0% |
| KDMN | Buy | KADMON HLDGS INC | $34,744,000 | +72.2% | 10,371,694 | +100.0% | 0.66% | -34.7% |
| AVDL | Buy | AVADEL PHARMACEUTICALS PLCsponsored adr | $32,530,000 | +106.4% | 3,098,010 | +116.8% | 0.62% | -21.7% |
| ONCE | New | SPARK THERAPEUTICS INC | $32,098,000 | – | 360,000 | – | 0.61% | – |
| ABEOW | Buy | ABEONA THERAPEUTICS INC*w exp 12/24/201 | $31,692,000 | +639.6% | 2,519,272 | +100.0% | 0.60% | +180.1% |
| ALQA | Buy | ALLIQUA BIOMEDICAL INC | $30,916,000 | +1874.2% | 8,467,902 | +100.0% | 0.59% | +646.8% |
| ASMB | Buy | ASSEMBLY BIOSCIENCES INC | $30,858,000 | +238.2% | 883,666 | +100.0% | 0.59% | +28.3% |
| EVH | Buy | EVOLENT HEALTH INCcl a | $30,260,000 | +11.1% | 1,700,000 | +58.2% | 0.58% | -57.8% |
| ITCI | New | INTRA CELLULAR THERAPIES INC | $29,334,000 | – | 1,858,920 | – | 0.56% | – |
| ATRS | Buy | ANTARES PHARMA INC | $28,214,000 | +105.3% | 8,707,794 | +104.1% | 0.54% | -22.0% |
| WVE | Buy | WAVE LIFE SCIENCES LTD | $27,960,000 | +126.8% | 1,285,596 | +94.0% | 0.53% | -13.9% |
| TFX | New | TELEFLEX INC | $26,714,000 | – | 110,400 | – | 0.51% | – |
| SYBX | New | SYNLOGIC INC | $26,100,000 | – | 1,372,704 | – | 0.50% | – |
| AVEO | Buy | AVEO PHARMACEUTICALS INC | $25,110,000 | +88.2% | 6,830,232 | +13.6% | 0.48% | -28.6% |
| BHVN | Buy | BIOHAVEN PHARMACTL HLDG CO L | $22,886,000 | +662.9% | 612,268 | +410.2% | 0.44% | +189.4% |
| ARGX | Buy | ARGENX SEsponsored adr | $20,196,000 | +111.6% | 900,000 | +100.0% | 0.39% | -19.6% |
| QURE | Buy | UNIQURE NV | $19,970,000 | +195.9% | 2,080,238 | +90.8% | 0.38% | +12.1% |
| ARDX | Buy | ARDELYX INC | $17,712,000 | +91.8% | 19,457,672 | +974.7% | 0.34% | -27.3% |
| ABMD | New | ABIOMED INC | $17,444,000 | – | 103,458 | – | 0.33% | – |
| ATHN | New | ATHENAHEALTH SHARES | $17,410,000 | – | 140,000 | – | 0.33% | – |
| MRNS | New | MARINUS PHARMACEUTICALS | $17,054,000 | – | 2,905,400 | – | 0.33% | – |
| URGN | Buy | UROGEN PHARMA LTD | $16,958,000 | +249.1% | 538,028 | +100.0% | 0.32% | +32.8% |
| Buy | ANI PHARMACEUTICALSnote 3.00% 12/0 | $16,238,000 | +105.3% | 15,000,000 | +100.0% | 0.31% | -22.1% | |
| OXFD | Buy | OXFORD IMMUNOTEC GLOBAL PLC | $15,636,000 | +2010.1% | 930,712 | +2010.2% | 0.30% | +708.1% |
| CSU | Buy | CAPITAL SR LIVING CORP | $14,062,000 | +74.4% | 1,120,346 | +111.3% | 0.27% | -34.0% |
| EXAS | Buy | EXACT SCIENCES CORP | $12,764,000 | +260.9% | 270,888 | +170.9% | 0.24% | +37.1% |
| CMTA | New | CLEMENTIA PHARMACEUTICALS IN | $12,582,000 | – | 704,500 | – | 0.24% | – |
| FOMX | Buy | FOAMIX PHARMACEUTICALS LTD | $12,402,000 | +139.2% | 2,234,648 | +100.0% | 0.24% | -9.2% |
| ZYME | Buy | ZYMEWORKS INC | $11,664,000 | +91.2% | 1,461,536 | +100.0% | 0.22% | -27.4% |
| ACRX | Sell | ACELRX PHARMACEUTICALS INC | $11,450,000 | +42.7% | 2,489,216 | -33.3% | 0.22% | -45.8% |
| SRRA | Buy | SIERRA ONCOLOGY INC | $11,332,000 | +165.0% | 7,310,372 | +100.0% | 0.22% | +0.5% |
| HRTX | New | HERON THERAPEUTICS INC | $10,658,000 | – | 660,000 | – | 0.20% | – |
| ICPT | New | INTERCEPT PHARMACEUTICALS IN | $10,448,000 | – | 180,000 | – | 0.20% | – |
| CLSD | Buy | CLEARSIDE BIOMEDICAL INC | $10,294,000 | +82.2% | 1,240,362 | +100.0% | 0.20% | -30.6% |
| ZLAB | New | ZAI LAB LTDadr | $9,450,000 | – | 350,000 | – | 0.18% | – |
| OMED | New | ONCOMED PHARMACEUTICALS INC | $9,386,000 | – | 2,076,578 | – | 0.18% | – |
| VSAR | Sell | VERSARTIS INC | $9,250,000 | -88.0% | 3,776,320 | -14.3% | 0.18% | -95.4% |
| NLNK | New | NEWLINK GENETICS CORP | $9,162,000 | – | 900,000 | – | 0.18% | – |
| MTEM | New | MOLECULAR TEMPLATES INC | $8,462,000 | – | 1,448,266 | – | 0.16% | – |
| MMSI | New | MERIT MEDICAL SYS INC | $8,470,000 | – | 200,000 | – | 0.16% | – |
| NEPT | Buy | NEPTUNE TECHNOLOGIES BIORESO | $8,226,000 | +116.4% | 13,039,268 | +100.0% | 0.16% | -17.8% |
| IVC | New | INVACARE CORP | $7,900,000 | – | 400,000 | – | 0.15% | – |
| GWPH | New | GW PHARMACEUTICALS PLCads | $7,462,000 | – | 73,526 | – | 0.14% | – |
| NCNA | New | NUCANA PLSsponsored adr | $7,348,000 | – | 400,000 | – | 0.14% | – |
| HSGX | Buy | HISTOGENICS CORP | $7,038,000 | +121.2% | 3,555,554 | +100.0% | 0.13% | -16.2% |
| RGEN | New | REPLIGEN INC | $6,698,000 | – | 174,800 | – | 0.13% | – |
| GILD | New | GILEAD SCIENCES INC | $6,482,000 | – | 80,000 | – | 0.12% | – |
| VRNA | Buy | VERONA PHARMA PLCsponsored adr | $6,140,000 | +163.4% | 400,000 | +100.0% | 0.12% | 0.0% |
| CRBP | Sell | CORBUS PHARMACEUTICALS HLDGS | $5,928,000 | -23.6% | 829,368 | -32.7% | 0.11% | -71.1% |
| DBVT | New | DBV TECHNOLOGIES S Aput | $5,616,000 | – | 1,100,000 | – | 0.11% | – |
| PFNX | Buy | PFENEX INC | $5,110,000 | +50.6% | 1,691,946 | +100.0% | 0.10% | -42.7% |
| VIVE | Buy | VIVEVE MEDICAL INC | $5,102,000 | -20.2% | 973,976 | +9.4% | 0.10% | -69.9% |
| OCRX | Buy | OCERA THERAPEUTICS INC | $4,648,000 | +96.5% | 4,077,760 | +100.0% | 0.09% | -25.2% |
| ALNY | New | ALNYLAM PHARMACEUTICALS INCcall | $4,630,000 | – | 200,000 | – | 0.09% | – |
| MGCD | Buy | MGC DIAGNOSTICS CORP | $4,522,000 | +111.3% | 504,654 | +100.0% | 0.09% | -20.4% |
| ADMA | Buy | ADMA BIOLOGICS INC | $4,442,000 | +60.4% | 1,442,204 | +100.0% | 0.08% | -38.8% |
| MCRB | New | SERES THERAPEUTICS INC | $4,330,000 | – | 270,000 | – | 0.08% | – |
| ABEO | Sell | ABEONA THERAPEUTICS INC | $3,986,000 | +47.3% | 233,800 | -44.7% | 0.08% | -44.1% |
| DCPH | New | DECIPHERA PHARMACEUTICALS IN | $3,892,000 | – | 205,000 | – | 0.07% | – |
| EIGR | Buy | EIGER BIOPHARMACEUTICALS INC | $3,468,000 | +178.6% | 315,358 | +100.0% | 0.07% | +4.8% |
| BCLI | Buy | BRAINSTORM CELL THERAPEUTICS | $3,296,000 | +98.6% | 800,000 | +100.0% | 0.06% | -25.0% |
| New | XENON PHARMACEUTICALS INC | $2,972,000 | – | 1,007,706 | – | 0.06% | – | |
| AFMD | Buy | AFFIMED N V | $3,006,000 | +119.6% | 1,336,428 | +100.0% | 0.06% | -17.4% |
| CSBR | Buy | CHAMPIONS ONCOLOGY INC | $2,836,000 | +200.7% | 773,080 | +110.7% | 0.05% | +14.9% |
| CRIS | Buy | CURIS INC | $2,834,000 | +57.6% | 1,902,402 | +100.0% | 0.05% | -40.0% |
| ZYNE | New | ZYNERBA PHARMACEUTICALS INC | $2,640,000 | – | 261,400 | – | 0.05% | – |
| OSUR | Buy | ORASURE TECHNOLOGIES INC | $2,462,000 | +160.5% | 109,458 | +100.0% | 0.05% | -2.1% |
| EXEL | Buy | EXELIXIS INC | $2,246,000 | +96.7% | 92,722 | +100.0% | 0.04% | -24.6% |
| FCAU | Buy | FIAT CHRYSLER AUTOMOBILES Nshrs | $2,220,000 | +236.9% | 124,000 | +100.0% | 0.04% | +27.3% |
| LNTH | Buy | LANTHEUS HLDGS INC | $1,914,000 | +101.7% | 107,526 | +100.0% | 0.04% | -22.9% |
| AZRX | Buy | AZURRX BIOPHARMA INC | $1,814,000 | +98.0% | 454,544 | +100.0% | 0.04% | -23.9% |
| CNC | Buy | CENTENE CORP DEL | $1,496,000 | +142.5% | 15,452 | +100.0% | 0.03% | -6.5% |
| VYGR | Buy | VOYAGER THERAPEUTICS INC | $1,424,000 | +359.4% | 69,208 | +100.0% | 0.03% | +68.8% |
| PRTO | Buy | PROTEON THERAPEUTICS INC | $1,336,000 | +157.9% | 668,232 | +100.0% | 0.03% | 0.0% |
| RACE | Buy | FERRARI N V | $1,370,000 | +157.0% | 12,400 | +100.0% | 0.03% | -3.7% |
| HSKA | Buy | HESKA CORP | $1,286,000 | +72.6% | 14,600 | +100.0% | 0.02% | -32.4% |
| ALGN | New | ALIGN TECHNOLOGY INC | $1,284,000 | – | 6,896 | – | 0.02% | – |
| INCY | Buy | INCYTE CORP | $1,312,000 | +85.6% | 11,238 | +100.0% | 0.02% | -30.6% |
| VNDA | Buy | VANDA PHARMACEUTICALS INC | $1,298,000 | +119.6% | 72,464 | +100.0% | 0.02% | -16.7% |
| KERX | New | KERYX BIOPHARMACEUTICALS INC | $1,184,000 | – | 166,772 | – | 0.02% | – |
| BGNE | New | BEIGENE LTDsponsored adr | $1,180,000 | – | 11,400 | – | 0.02% | – |
| PRAH | New | PRA HEALTH SCIENCES INC | $1,132,000 | – | 14,854 | – | 0.02% | – |
| ATRA | New | ATARA BIOTHERAPEUTICS INC | $1,162,000 | – | 70,212 | – | 0.02% | – |
| ESPR | New | ESPERION THERAPEUTICS INC NE | $1,080,000 | – | 21,538 | – | 0.02% | – |
| PRTK | New | PARATEK PHARMACEUTICALS INC | $1,064,000 | – | 42,372 | – | 0.02% | – |
| IMGN | New | IMMUNOGEN INC | $1,072,000 | – | 140,252 | – | 0.02% | – |
| INOV | New | INOVALON HLDGS INC | $1,022,000 | – | 60,000 | – | 0.02% | – |
| TDOC | New | TELADOC INC | $970,000 | – | 29,282 | – | 0.02% | – |
| CUTR | Buy | CUTERA INC | $990,000 | +219.4% | 23,962 | +100.0% | 0.02% | +18.8% |
| FGEN | New | FIBROGEN INC | $924,000 | – | 17,186 | – | 0.02% | – |
| AKAOQ | Buy | ACHAOGEN INC | $878,000 | +46.6% | 55,102 | +100.0% | 0.02% | -43.3% |
| ZSAN | Buy | ZOSANO PHARMA INC | $824,000 | +16.9% | 1,000,000 | +100.0% | 0.02% | -54.3% |
| PTLA | Buy | PORTOLA PHARMACEUTICALS INC | $850,000 | +92.3% | 15,740 | +100.0% | 0.02% | -27.3% |
| Buy | PERNIX THERAPEUTICS HLDGS INdbcv 4.250% 4/0 | $840,000 | +197.9% | 2,000,000 | +100.0% | 0.02% | +14.3% | |
| New | NABRIVA THERAPEUTICS PLC | $862,000 | – | 105,140 | – | 0.02% | – | |
| MOH | New | MOLINA HEALTHCARE INCcall | $690,000 | – | 100,000 | – | 0.01% | – |
| ICPT | New | INTERCEPT PHARMACEUTICALS INcall | $566,000 | – | 500,000 | – | 0.01% | – |
| HCM | New | HUTCHISON CHINA MEDITECH LTDsponsored adr | $546,000 | – | 20,000 | – | 0.01% | – |
| ACST | Buy | ACASTI PHARMA INCcl a new | $534,000 | +116.2% | 373,118 | +100.0% | 0.01% | -16.7% |
| SAGE | Buy | SAGE THERAPEUTICS INCcall | $356,000 | -98.4% | 430,000 | +56.4% | 0.01% | -99.4% |
| SENS | New | SENSEONICS HOLDINGS INC | $320,000 | – | 100,000 | – | 0.01% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INCput | $90,000 | – | 840,000 | – | 0.00% | – |
| INCY | New | INCYTE CORPcall | $70,000 | – | 200,000 | – | 0.00% | – |
| IONS | New | IONIS PHARMACEUTICALS INCcall | $48,000 | – | 120,000 | – | 0.00% | – |
| PPHM | Exit | PEREGRINE PHARMACEUTICALS IN | $0 | – | -24,332 | – | -0.00% | – |
| ONSIZ | Exit | ONCOBIOLOGICS INC*w exp 05/18/201 | $0 | – | -462,500 | – | -0.00% | – |
| ONSIW | Exit | ONCOBIOLOGICS INCw exp 02/18/201 | $0 | – | -462,500 | – | -0.00% | – |
| ARNI | Exit | ARNO THERAPEUTICS INC | $0 | – | -4,177,577 | – | -0.01% | – |
| CDTX | Exit | CIDARA THERAPEUTICS INC | $0 | – | -62,110 | – | -0.02% | – |
| DPLO | Exit | DIPLOMAT PHARMACY INC | $0 | – | -30,658 | – | -0.02% | – |
| INCR | Exit | INC RESH HLDGS INCcl a | $0 | – | -8,532 | – | -0.02% | – |
| ICLR | Exit | ICON PLC | $0 | – | -5,187 | – | -0.03% | – |
| MOH | Exit | MOLINA HEALTHCARE INC | $0 | – | -8,140 | – | -0.03% | – |
| ACOR | Exit | ACORDA THERAPEUTICS INC | $0 | – | -31,786 | – | -0.03% | – |
| HRC | Exit | HILL ROM HLDGS INC | $0 | – | -7,930 | – | -0.03% | – |
| EW | Exit | EDWARDS LIFESCIENCES CORP | $0 | – | -6,088 | – | -0.04% | – |
| LHCG | Exit | LHC GROUP INC | $0 | – | -10,730 | – | -0.04% | – |
| ONS | Exit | ONCOBIOLOGICS INC | $0 | – | -837,886 | – | -0.04% | – |
| WCG | Exit | WELLCARE HEALTH PLANS INC | $0 | – | -5,056 | – | -0.05% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS IN | $0 | – | -847,458 | – | -0.07% | – |
| CARA | Exit | CARA THERAPEUTICS INCcall | $0 | – | -100,000 | – | -0.08% | – |
| PSDV | Exit | PSIVIDA CORP | $0 | – | -1,149,556 | – | -0.10% | – |
| ADMP | Exit | ADAMIS PHARMACEUTICALS CORP | $0 | – | -400,000 | – | -0.10% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -20,000 | – | -0.11% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -723,853 | – | -0.12% | – |
| FWP | Exit | FORWARD PHARMA A/Ssponsored adr | $0 | – | -194,718 | – | -0.20% | – |
| UNH | Exit | UNITEDHEALTH GROUP INC | $0 | – | -28,480 | – | -0.27% | – |
| ANIP | Exit | ANI PHARMACEUTICALS INC | $0 | – | -125,399 | – | -0.30% | – |
| RARE | Exit | ULTRAGENYX PHARMACEUTICAL INcall | $0 | – | -100,000 | – | -0.31% | – |
| AXGT | Exit | AXOVANT SCIENCES LTDcall | $0 | – | -300,000 | – | -0.35% | – |
| EGRX | Exit | EAGLE PHARMACEUTICALS INC | $0 | – | -100,000 | – | -0.40% | – |
| RDUS | Exit | RADIUS HEALTH INCput | $0 | – | -200,000 | – | -0.46% | – |
| ZYNE | Exit | ZYNERBA PHARMACEUTICALS INCput | $0 | – | -100,000 | – | -0.51% | – |
| AXGT | Exit | AXOVANT SCIENCES LTD | $0 | – | -572,700 | – | -0.67% | – |
| JAZZ | Exit | JAZZ PHARMACEUTICALS PLC | $0 | – | -85,572 | – | -0.67% | – |
| RDUS | Exit | RADIUS HEALTH INC | $0 | – | -645,873 | – | -1.47% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS | $0 | – | -1,089,961 | – | -1.85% | – |
Q2 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FOLD | New | AMICUS THERAPEUTICS INC | $174,178,000 | – | 17,296,672 | – | 8.76% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $164,569,000 | – | 3,577,589 | – | 8.28% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $146,181,000 | – | 1,832,761 | – | 7.36% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $107,592,000 | – | 3,933,927 | – | 5.41% | – |
| VSAR | New | VERSARTIS INC | $76,907,000 | – | 4,407,317 | – | 3.87% | – |
| LJPC | New | LA JOLLA PHARMACEUTICAL CO | $64,214,000 | – | 2,157,011 | – | 3.23% | – |
| PBYI | New | PUMA BIOTECHNOLOGY INC | $64,092,000 | – | 733,320 | – | 3.22% | – |
| RTRX | New | RETROPHIN INC | $51,816,000 | – | 2,672,309 | – | 2.61% | – |
| TSRO | New | TESARO INC | $50,287,000 | – | 359,551 | – | 2.53% | – |
| ZGNX | New | ZOGENIX INC | $50,000,000 | – | 3,448,302 | – | 2.52% | – |
| CORI | New | CORIUM INTL INC | $43,620,000 | – | 5,847,133 | – | 2.20% | – |
| NXTM | New | NXSTAGE MEDICAL INC | $38,997,000 | – | 1,555,523 | – | 1.96% | – |
| DOVA | New | DOVA PHARMACEUTICALS INC | $38,037,000 | – | 1,706,499 | – | 1.91% | – |
| SRPT | New | SAREPTA THERAPEUTICS | $36,743,000 | – | 1,089,961 | – | 1.85% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $35,742,000 | – | 277,352 | – | 1.80% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $32,068,000 | – | 4,363,114 | – | 1.61% | – |
| RDUS | New | RADIUS HEALTH INC | $29,212,000 | – | 645,873 | – | 1.47% | – |
| VBIV | New | VBI VACCINES IN | $28,561,000 | – | 6,565,843 | – | 1.44% | – |
| XNCR | New | XENCOR INC | $27,297,000 | – | 1,293,095 | – | 1.37% | – |
| EVH | New | EVOLENT HEALTH INCcl a | $27,234,000 | – | 1,074,327 | – | 1.37% | – |
| RGNX | New | REGENXBIO INC | $27,080,000 | – | 1,371,186 | – | 1.36% | – |
| QTNT | New | QUOTIENT LTD | $26,010,000 | – | 3,714,486 | – | 1.31% | – |
| ANAB | New | ANAPTYSBIO INC | $22,788,000 | – | 952,269 | – | 1.15% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $22,530,000 | – | 444,661 | – | 1.13% | – |
| AVXS | New | AVEXIS INC | $22,280,000 | – | 271,181 | – | 1.12% | – |
| SAGE | New | SAGE THERAPEUTICS INCcall | $21,901,000 | – | 275,000 | – | 1.10% | – |
| XLRN | New | ACCELERON PHARMA INC | $21,615,000 | – | 711,259 | – | 1.09% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $21,550,000 | – | 1,390,381 | – | 1.08% | – |
| DBVT | New | DBV TECHNOLOGIES S Asponsored adr | $21,131,000 | – | 591,765 | – | 1.06% | – |
| KDMN | New | KADMON HLDGS INC | $20,172,000 | – | 5,185,847 | – | 1.02% | – |
| ISRG | New | INTUITIVE SURGICAL INC | $19,357,000 | – | 20,695 | – | 0.97% | – |
| HUM | New | HUMANA INC | $18,791,000 | – | 78,093 | – | 0.95% | – |
| ALBO | New | ALBIREO PHARMA INC | $17,407,000 | – | 845,000 | – | 0.88% | – |
| GLPG | New | GALAPAGOS NVspon adr | $17,325,000 | – | 226,405 | – | 0.87% | – |
| SELB | New | SELECTA BIOSCIENCES INC | $15,834,000 | – | 797,325 | – | 0.80% | – |
| AKBA | New | AKEBIA THERAPEUTICS INC | $15,808,000 | – | 1,100,000 | – | 0.80% | – |
| AVDL | New | AVADEL PHARMACEUTICALS PLCsponsored adr | $15,763,000 | – | 1,429,114 | – | 0.79% | – |
| MYOK | New | MYOKARDIA INC | $14,492,000 | – | 553,154 | – | 0.73% | – |
| ATRS | New | ANTARES PHARMA INC | $13,741,000 | – | 4,267,253 | – | 0.69% | – |
| BOLD | New | AUDENTES THERAPEUTICS INC | $13,534,000 | – | 707,500 | – | 0.68% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $13,417,000 | – | 2,885,458 | – | 0.68% | – |
| AVEO | New | AVEO PHARMACEUTICALS INC | $13,343,000 | – | 6,010,660 | – | 0.67% | – |
| JAZZ | New | JAZZ PHARMACEUTICALS PLC | $13,306,000 | – | 85,572 | – | 0.67% | – |
| AXGT | New | AXOVANT SCIENCES LTD | $13,281,000 | – | 572,700 | – | 0.67% | – |
| WVE | New | WAVE LIFE SCIENCES LTD | $12,328,000 | – | 662,798 | – | 0.62% | – |
| IRTC | New | IRHYTHM TECHNOLOGIES INC | $12,019,000 | – | 282,857 | – | 0.60% | – |
| ZYNE | New | ZYNERBA PHARMACEUTICALS INCput | $10,164,000 | – | 100,000 | – | 0.51% | – |
| ARGX | New | ARGENX SEsponsored adr | $9,544,000 | – | 450,000 | – | 0.48% | – |
| ARDX | New | ARDELYX INC | $9,233,000 | – | 1,810,581 | – | 0.46% | – |
| ASMB | New | ASSEMBLY BIOSCIENCES INC | $9,124,000 | – | 441,833 | – | 0.46% | – |
| RDUS | New | RADIUS HEALTH INCput | $9,046,000 | – | 200,000 | – | 0.46% | – |
| CSU | New | CAPITAL SR LIVING CORP | $8,064,000 | – | 530,173 | – | 0.41% | – |
| ACRX | New | ACELRX PHARMACEUTICALS INC | $8,022,000 | – | 3,731,342 | – | 0.40% | – |
| New | ANI PHARMACEUTICALS INCnote 3.000%12/0 | $7,908,000 | – | 7,500,000 | – | 0.40% | – | |
| EGRX | New | EAGLE PHARMACEUTICALS INC | $7,889,000 | – | 100,000 | – | 0.40% | – |
| CRBP | New | CORBUS PHARMACEUTICALS HLDGS | $7,764,000 | – | 1,232,500 | – | 0.39% | – |
| AXGT | New | AXOVANT SCIENCES LTDcall | $6,957,000 | – | 300,000 | – | 0.35% | – |
| QURE | New | UNIQURE NV | $6,748,000 | – | 1,090,119 | – | 0.34% | – |
| VIVE | New | VIVEVE MED INC | $6,394,000 | – | 890,468 | – | 0.32% | – |
| RARE | New | ULTRAGENYX PHARMACEUTICAL INcall | $6,211,000 | – | 100,000 | – | 0.31% | – |
| NVTA | New | INVITAE CORP | $6,209,000 | – | 649,500 | – | 0.31% | – |
| ZYME | New | ZYMEWORKS INC | $6,101,000 | – | 730,768 | – | 0.31% | – |
| ANIP | New | ANI PHARMACEUTICALS INC | $5,869,000 | – | 125,399 | – | 0.30% | – |
| CLSD | New | CLEARSIDE BIOMEDICAL INC | $5,649,000 | – | 620,181 | – | 0.28% | – |
| UNH | New | UNITEDHEALTH GROUP INC | $5,281,000 | – | 28,480 | – | 0.27% | – |
| FOMX | New | FOAMIX PHARMACEUTICALS LTD | $5,184,000 | – | 1,117,324 | – | 0.26% | – |
| URGN | New | UROGEN PHARMA LTD | $4,858,000 | – | 269,014 | – | 0.24% | – |
| ABEOW | New | ABEONA THERAPEUTICS INC*w exp 12/24/201 | $4,285,000 | – | 1,259,636 | – | 0.22% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $4,277,000 | – | 3,655,186 | – | 0.22% | – |
| FWP | New | FORWARD PHARMA A/Ssponsored adr | $3,959,000 | – | 194,718 | – | 0.20% | – |
| NEPT | New | NEPTUNE TECHNOLOGIES BIORESO | $3,801,000 | – | 6,519,634 | – | 0.19% | – |
| EXAS | New | EXACT SCIENCES CORP | $3,537,000 | – | 100,000 | – | 0.18% | – |
| PFNX | New | PFENEX INC | $3,392,000 | – | 845,973 | – | 0.17% | – |
| HSGX | New | HISTOGENICS CORP | $3,182,000 | – | 1,777,777 | – | 0.16% | – |
| BHVN | New | BIOHAVEN PHARMACTL HLDG CO L | $3,000,000 | – | 120,000 | – | 0.15% | – |
| ADMA | New | ADMA BIOLOGICS INC | $2,769,000 | – | 721,102 | – | 0.14% | – |
| ABEO | New | ABEONA THERAPEUTICS INC | $2,706,000 | – | 422,873 | – | 0.14% | – |
| OCRX | New | OCERA THERAPEUTICS INC | $2,365,000 | – | 2,038,880 | – | 0.12% | – |
| VRNA | New | VERONA PHARMA PLCsponsored ads | $2,331,000 | – | 200,000 | – | 0.12% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $2,280,000 | – | 723,853 | – | 0.12% | – |
| MGCD | New | MGC DIAGNOSTICS CORP | $2,140,000 | – | 252,327 | – | 0.11% | – |
| BLUE | New | BLUEBIRD BIO INC | $2,101,000 | – | 20,000 | – | 0.11% | – |
| ADMP | New | ADAMIS PHARMACEUTICALS CORP | $2,080,000 | – | 400,000 | – | 0.10% | – |
| PSDV | New | PSIVIDA CORP | $1,966,000 | – | 1,149,556 | – | 0.10% | – |
| CRIS | New | CURIS INC | $1,798,000 | – | 951,201 | – | 0.09% | – |
| BCLI | New | BRAINSTORM CELL THERAPEUTICS | $1,660,000 | – | 400,000 | – | 0.08% | – |
| ALQA | New | ALLIQUA BIOMEDICAL INC | $1,566,000 | – | 4,233,951 | – | 0.08% | – |
| CARA | New | CARA THERAPEUTICS INCcall | $1,539,000 | – | 100,000 | – | 0.08% | – |
| ARWR | New | ARROWHEAD PHARMACEUTICALS IN | $1,372,000 | – | 847,458 | – | 0.07% | – |
| AFMD | New | AFFIMED N V | $1,369,000 | – | 668,214 | – | 0.07% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $1,245,000 | – | 157,679 | – | 0.06% | – |
| EXEL | New | EXELIXIS SHARES | $1,142,000 | – | 46,361 | – | 0.06% | – |
| LNTH | New | LANTHEUS HLDGS INC | $949,000 | – | 53,763 | – | 0.05% | – |
| OSUR | New | ORASURE TECHNOLOGIES INC | $945,000 | – | 54,729 | – | 0.05% | – |
| CSBR | New | CHAMPIONS ONCOLOGY INC | $943,000 | – | 366,973 | – | 0.05% | – |
| WCG | New | WELLCARE HEALTH PLANS INC | $908,000 | – | 5,056 | – | 0.05% | – |
| AZRX | New | AZURRX BIOPHARMA INC | $916,000 | – | 227,272 | – | 0.05% | – |
| ONS | New | ONCOBIOLOGICS INC | $837,000 | – | 837,886 | – | 0.04% | – |
| HSKA | New | HESKA CORP | $745,000 | – | 7,300 | – | 0.04% | – |
| OXFD | New | OXFORD IMMUNOTEC GLOBAL PLC | $741,000 | – | 44,106 | – | 0.04% | – |
| LHCG | New | LHC GROUP INC | $728,000 | – | 10,730 | – | 0.04% | – |
| EW | New | EDWARDS LIFESCIENCES CORP | $719,000 | – | 6,088 | – | 0.04% | – |
| INCY | New | INCYTE CORP | $707,000 | – | 5,619 | – | 0.04% | – |
| ZSAN | New | ZOSANO PHARMA CORP | $705,000 | – | 500,000 | – | 0.04% | – |
| FCAU | New | FIAT CHRYSLER AUTOMOBILES N | $659,000 | – | 62,000 | – | 0.03% | – |
| ACOR | New | ACORDA THERAPEUTICS INC | $626,000 | – | 31,786 | – | 0.03% | – |
| HRC | New | HILL ROM HLDGS INC | $631,000 | – | 7,930 | – | 0.03% | – |
| CNC | New | CENTENE CORP DEL | $617,000 | – | 7,726 | – | 0.03% | – |
| AKAOQ | New | ACHAOGEN INC | $599,000 | – | 27,551 | – | 0.03% | – |
| VNDA | New | VANDA PHARMACEUTICALS INC | $591,000 | – | 36,232 | – | 0.03% | – |
| MOH | New | MOLINA HEALTHCARE INC | $563,000 | – | 8,140 | – | 0.03% | – |
| RACE | New | FERRARI N V | $533,000 | – | 6,200 | – | 0.03% | – |
| ICLR | New | ICON PLC | $507,000 | – | 5,187 | – | 0.03% | – |
| PRTO | New | PROTEON THERAPEUTICS INC | $518,000 | – | 334,116 | – | 0.03% | – |
| INCR | New | INC RESH HLDGS INCcl a | $499,000 | – | 8,532 | – | 0.02% | – |
| CDTX | New | CIDARA THERAPEUTICS INC | $465,000 | – | 62,110 | – | 0.02% | – |
| DPLO | New | DIPLOMAT PHARMACY INC | $454,000 | – | 30,658 | – | 0.02% | – |
| PTLA | New | PORTOLA PHARMACEUTICALS INC | $442,000 | – | 7,870 | – | 0.02% | – |
| CUTR | New | CUTERA INC | $310,000 | – | 11,981 | – | 0.02% | – |
| VYGR | New | VOYAGER THERAPEUTICS INC | $310,000 | – | 34,604 | – | 0.02% | – |
| New | PERNIX THERAPEUTICS HLDGS INdbcv 4.250% 4/0 | $282,000 | – | 1,000,000 | – | 0.01% | – | |
| ACST | New | ACASTI PHARMA INC | $247,000 | – | 186,559 | – | 0.01% | – |
| ARNI | New | ARNO THERAPEUTICS INC | $208,000 | – | 4,177,577 | – | 0.01% | – |
| ONSIW | New | ONCOBIOLOGICS INCw exp 02/18/201 | $80,000 | – | 462,500 | – | 0.00% | – |
| ONSIZ | New | ONCOBIOLOGICS INC*w exp 05/18/201 | $42,000 | – | 462,500 | – | 0.00% | – |
| PPHM | New | PEREGRINE PHARMACEUTICALS IN | $15,000 | – | 24,332 | – | 0.00% | – |
Q4 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| EGRX | Exit | EAGLE PHARMACEUTICALS INC | $0 | – | -544,770 | – | 0.00% | – |
| AVGR | Exit | AVINGER INC | $0 | – | -1,062 | – | 0.00% | – |
| INGN | Exit | INOGEN INC | $0 | – | -125 | – | 0.00% | – |
| NPCUF | Exit | ALLON THERAPEUTICS INC | $0 | – | -751,124 | – | 0.00% | – |
| SGMO | Exit | SANGAMO BIOSCIENCES INC | $0 | – | -272 | – | 0.00% | – |
| FLKS | Exit | FLEX PHARMA INC | $0 | – | -237 | – | 0.00% | – |
| MD | Exit | MEDNAX INC | $0 | – | -29 | – | 0.00% | – |
| CRY | Exit | CRYOLIFE INC | $0 | – | -123 | – | 0.00% | – |
| TNGNQ | Exit | TENGION INC | $0 | – | -1,826,399 | – | 0.00% | – |
| DSCI | Exit | DERMA SCIENCES INC | $0 | – | -2,970 | – | -0.00% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -250 | – | -0.00% | – |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -5,343 | – | -0.00% | – |
| CAPR | Exit | CAPRICOR THERAPEUTICS INC | $0 | – | -4,000 | – | -0.00% | – |
| PPHM | Exit | PEREGRINE PHARMACEUTICALS | $0 | – | -24,332 | – | -0.00% | – |
| Exit | SEVION THERAPEUTICS INC | $0 | – | -59,220 | – | -0.00% | – | |
| CYNO | Exit | CYNOSURE INC CLASS A | $0 | – | -1,800 | – | -0.01% | – |
| ACETQ | Exit | ACETO CORP | $0 | – | -6,054 | – | -0.01% | – |
| STML | Exit | STEMLINE THERAPEUTICS INC | $0 | – | -10,702 | – | -0.01% | – |
| DRAD | Exit | DIGIRAD CORP | $0 | – | -24,988 | – | -0.01% | – |
| ATRC | Exit | ATRICURE INC | $0 | – | -7,949 | – | -0.01% | – |
| HNGR | Exit | HANGER INC | $0 | – | -15,038 | – | -0.01% | – |
| IVC | Exit | INVACARE CORP | $0 | – | -13,200 | – | -0.01% | – |
| BOLD | Exit | AUDENTES THERAPEUTICS INC | $0 | – | -7,500 | – | -0.01% | – |
| ISRG | Exit | INTUITIVE SURGICAL INC | $0 | – | -200 | – | -0.01% | – |
| MDSO | Exit | MEDIDATA SOLUTIONS INC | $0 | – | -2,865 | – | -0.01% | – |
| LHCG | Exit | LHC GROUP INC | $0 | – | -4,745 | – | -0.01% | – |
| MTD | Exit | METTLER TOLEDO INTERNATIONAL | $0 | – | -415 | – | -0.01% | – |
| AMRI | Exit | ALBANY MOLECULAR RESEARCH | $0 | – | -10,300 | – | -0.01% | – |
| ARAY | Exit | ACCURAY INC | $0 | – | -27,300 | – | -0.01% | – |
| NUVA | Exit | NUVASIVE INC | $0 | – | -2,589 | – | -0.01% | – |
| CGNT | Exit | COGENTIX MEDICAL INC | $0 | – | -99,008 | – | -0.01% | – |
| GKOS | Exit | GLAUKOS CORP | $0 | – | -5,300 | – | -0.01% | – |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -18,541 | – | -0.01% | – |
| NSTG | Exit | NANOSTRING TECHNOLOGIES INC | $0 | – | -10,518 | – | -0.01% | – |
| BVX | Exit | BOVIE MEDICAL CORP | $0 | – | -48,544 | – | -0.02% | – |
| PMD | Exit | PSYCHEMEDICS CORP | $0 | – | -12,626 | – | -0.02% | – |
| LLY | Exit | ELI LILLY & CO CALL 90 01/20/2017call | $0 | – | -1,000 | – | -0.02% | – |
| NTLA | Exit | INTELLIA THERAPEUTICS INC | $0 | – | -14,673 | – | -0.02% | – |
| GNVC | Exit | GENVEC INC | $0 | – | -561,320 | – | -0.02% | – |
| TDOC | Exit | TELADOC INC | $0 | – | -15,000 | – | -0.02% | – |
| Exit | PERNIX THERAPEUTICS HLDINGS INCdbcv 4.25% 4/01/2021 | $0 | – | -1,000,000 | – | -0.02% | – | |
| MNKKQ | Exit | MALLINCKRODT PLC | $0 | – | -4,500 | – | -0.02% | – |
| ACHI | Exit | ACCRETIVE HEALTH INC | $0 | – | -125,000 | – | -0.02% | – |
| MACK | Exit | MERRIMACK PHARMACEUTICALS INC | $0 | – | -48,910 | – | -0.02% | – |
| ONSIW | Exit | ONCOBIOLOGICS INC*w exp 2/18/2017 | $0 | – | -656,382 | – | -0.02% | – |
| RACE | Exit | FERRARI NV | $0 | – | -6,200 | – | -0.02% | – |
| ENZ | Exit | ENZO BIOCHEM INC | $0 | – | -67,113 | – | -0.02% | – |
| THC | Exit | TENET HEALTHCARE CORP | $0 | – | -16,200 | – | -0.02% | – |
| FCAU | Exit | FIAT CHRYSLER AUTOMOBILES NV | $0 | – | -62,000 | – | -0.03% | – |
| ACST | Exit | ACASTI PHARMA INC | $0 | – | -236,559 | – | -0.03% | – |
| ANTM | Exit | ANTHEM INC | $0 | – | -3,400 | – | -0.03% | – |
| Q | Exit | QUINTILES IMS HOLDINGS INC | $0 | – | -5,103 | – | -0.03% | – |
| AMN | Exit | AMN HEALTHCARE INC | $0 | – | -13,445 | – | -0.03% | – |
| KND | Exit | KINDRED HEATHCARE INC | $0 | – | -42,301 | – | -0.03% | – |
| AFAM | Exit | ALMOST FAMILY INC | $0 | – | -11,942 | – | -0.03% | – |
| LNTH | Exit | LANTHEUS HOLDINGS INC | $0 | – | -53,763 | – | -0.03% | – |
| AMSG | Exit | AMSURG CORP | $0 | – | -6,618 | – | -0.03% | – |
| UNH | Exit | UNITEDHEALTH GROUP INC | $0 | – | -3,231 | – | -0.03% | – |
| CRL | Exit | CHARLES RIVER LABORATORIES | $0 | – | -5,482 | – | -0.03% | – |
| HCA | Exit | HCA HOLDINGS INC | $0 | – | -6,202 | – | -0.03% | – |
| MGLN | Exit | MAGELLAN HEALTH INC | $0 | – | -8,772 | – | -0.03% | – |
| AMAG | Exit | AMAG PHARMACEUTICALS INC | $0 | – | -19,524 | – | -0.03% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INC | $0 | – | -7,344 | – | -0.03% | – |
| SGYPQ | Exit | SYNERGY PHARMACEUTICALS INC | $0 | – | -89,127 | – | -0.03% | – |
| UHS | Exit | UNIVERSAL HEALTH SERVICES CLASS B | $0 | – | -3,989 | – | -0.03% | – |
| CAH | Exit | CARDINAL HEALTH INC | $0 | – | -6,398 | – | -0.03% | – |
| A | Exit | AGILENT TECHNOLOGIES INC | $0 | – | -10,540 | – | -0.03% | – |
| MCK | Exit | MCKESSON CORP | $0 | – | -2,979 | – | -0.03% | – |
| SCMP | Exit | SUCAMPO PHARMACEUTICALS CLASS A | $0 | – | -41,096 | – | -0.03% | – |
| AET | Exit | AETNA INC | $0 | – | -4,454 | – | -0.03% | – |
| MOH | Exit | MOLINA HEALTHCARE INC | $0 | – | -8,879 | – | -0.03% | – |
| PZRXQ | Exit | PHASERX INC | $0 | – | -200,000 | – | -0.03% | – |
| ABC | Exit | AMERISOURCEBERGEN CORP | $0 | – | -6,500 | – | -0.03% | – |
| ICLR | Exit | ICON INC | $0 | – | -6,873 | – | -0.03% | – |
| VWR | Exit | VWR CORP | $0 | – | -18,657 | – | -0.03% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -5,619 | – | -0.03% | – |
| HUM | Exit | HUMANA INC CALL 190 04/21/2017call | $0 | – | -400 | – | -0.03% | – |
| LH | Exit | LABORATORY CORPORATION OF AMERICA HOLDINGS | $0 | – | -3,990 | – | -0.04% | – |
| WOOF | Exit | VCA INC | $0 | – | -7,940 | – | -0.04% | – |
| INCR | Exit | INC RESEARCH HOLDINGS INC CLASS A | $0 | – | -12,636 | – | -0.04% | – |
| UTHR | Exit | UNITED THERAPEUTICS INC | $0 | – | -4,753 | – | -0.04% | – |
| HWAY | Exit | HEALTHWAYS INC | $0 | – | -21,608 | – | -0.04% | – |
| IMDZ | Exit | IMMUNE DESIGN CORP | $0 | – | -77,725 | – | -0.04% | – |
| WCG | Exit | WELLCARE HEALTHCARE PLANS INC | $0 | – | -5,056 | – | -0.04% | – |
| HRC | Exit | HILL ROM HOLDINGS INC | $0 | – | -9,563 | – | -0.04% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -1,921 | – | -0.04% | – |
| CSBR | Exit | CHAMPIONS ONCOLOGY INC | $0 | – | -372,597 | – | -0.04% | – |
| AGLE | Exit | AEGLEA BIOTHERAPEUTICS INC | $0 | – | -103,585 | – | -0.04% | – |
| PAHC | Exit | PHIBRO ANIMAL HEALTH CLASS A | $0 | – | -24,300 | – | -0.04% | – |
| SCYX | Exit | SCYNEXIS INC | $0 | – | -171,185 | – | -0.04% | – |
| LCI | Exit | LANNETT COMPANY INC | $0 | – | -26,670 | – | -0.05% | – |
| ANIP | Exit | ANI PHARMACEUTICALS INC | $0 | – | -11,561 | – | -0.05% | – |
| ONSIZ | Exit | ONCOBIOLOGICS INC*w exp 2/18/2017 | $0 | – | -656,382 | – | -0.05% | – |
| ATRS | Exit | ANTARES PHARMA INC | $0 | – | 0 | – | -0.06% | – |
| BCLI | Exit | BRAINSTORM CELL THERAPEUTICS | $0 | – | -400,000 | – | -0.06% | – |
| NVLS | Exit | NIVALIS THERAPEUTICS INC | $0 | – | -122,275 | – | -0.06% | – |
| NVRO | Exit | NEVRO CORP | $0 | – | -11,746 | – | -0.08% | – |
| ALQA | Exit | ALLIQUA BIOMEDICAL INC | $0 | – | -1,921,951 | – | -0.10% | – |
| VCEL | Exit | VERICEL CORP | $0 | – | -544,996 | – | -0.10% | – |
| VCRA | Exit | VOCERA COMMUNICATIONS INC | $0 | – | -94,236 | – | -0.10% | – |
| BIO | Exit | BIO RAD LABORATORIES CLASS A | $0 | – | -10,000 | – | -0.11% | – |
| MDGN | Exit | MEDGENICS INC | $0 | – | -293,460 | – | -0.11% | – |
| CBPO | Exit | CHINA BIOLOGIC PRODUCTS INC | $0 | – | -13,695 | – | -0.11% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -129,920 | – | -0.11% | – |
| ABT | Exit | ABBOTT LABORATORIES | $0 | – | -46,019 | – | -0.13% | – |
| ARNI | Exit | ARNO THERAPEUTICS INC | $0 | – | -4,177,577 | – | -0.13% | – |
| AFMD | Exit | AFFIMED NV | $0 | – | -734,301 | – | -0.13% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -65,240 | – | -0.13% | – |
| RXDX | Exit | IGNYTA INC | $0 | – | -339,727 | – | -0.14% | – |
| NEOS | Exit | NEOS THERAPEUTICS INC | $0 | – | -330,593 | – | -0.14% | – |
| MGCD | Exit | MGC DIAGNOSTICS CORP | $0 | – | -329,733 | – | -0.15% | – |
| PRTO | Exit | PROTEON THERAPEUTICS INC | $0 | – | -269,005 | – | -0.16% | – |
| APVO | Exit | APTEVO THERAPEUTICS INC | $0 | – | -988,133 | – | -0.16% | – |
| OPHT | Exit | OPHTHOTECH CORP CALL 80 12/16/2016call | $0 | – | -600,000 | – | -0.18% | – |
| AVEO | Exit | AVEO PHARMACEUTICALS INC | $0 | – | -3,108,808 | – | -0.18% | – |
| INNL | Exit | INNOCOLL HOLDINGS PLC | $0 | – | -547,792 | – | -0.21% | – |
| MYL | Exit | MYLAN NV | $0 | – | -94,711 | – | -0.23% | – |
| BGNE | Exit | BEIGENE LTDdepository receipt | $0 | – | -132,057 | – | -0.26% | – |
| ABEOW | Exit | ABEONA THERAPEUTICS INC-CW19warrants | $0 | – | -1,259,636 | – | -0.26% | – |
| AGTC | Exit | APPLIED GENETIC TECHNOLOGIES | $0 | – | -426,048 | – | -0.27% | – |
| CEMP | Exit | CEMPRA INC | $0 | – | -175,503 | – | -0.27% | – |
| CLLS | Exit | CELLECTIS ADRdepository receipt | $0 | – | -179,506 | – | -0.28% | – |
| ANTH | Exit | ANTHERA PHARMACEUTICALS INC | $0 | – | -1,459,627 | – | -0.30% | – |
| Exit | NEURODERM LTD | $0 | – | -264,114 | – | -0.32% | – | |
| SELB | Exit | SELECTA BIOSCIENCES INC | $0 | – | -348,150 | – | -0.32% | – |
| AMRN | Exit | AMARIN CORP PLC-ADRdepository receipt | $0 | – | -1,622,280 | – | -0.33% | – |
| ONS | Exit | ONCOBIOLOGICS INC | $0 | – | -1,248,990 | – | -0.34% | – |
| ADMA | Exit | ADMA BIOLOGICS INC | $0 | – | -734,793 | – | -0.34% | – |
| PTI | Exit | PROTEOSTASIS THERAPEUTICS INC | $0 | – | -344,550 | – | -0.35% | – |
| CASC | Exit | CASCADIAN THERAPEUTICS INC | $0 | – | -3,414,121 | – | -0.36% | – |
| ASMB | Exit | ASSEMBLY BIOSCIENCES INC | $0 | – | -777,669 | – | -0.36% | – |
| HSGX | Exit | HISTOGENCIS CORP | $0 | – | -1,777,777 | – | -0.37% | – |
| SUPN | Exit | SUPERNUS PHARMACEUTICALS INC | $0 | – | -244,550 | – | -0.39% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -171,500 | – | -0.40% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -762,800 | – | -0.40% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS INC | $0 | – | -847,458 | – | -0.40% | – |
| CSU | Exit | CAPITAL SENIOR LIVING CORP | $0 | – | -375,306 | – | -0.41% | – |
| AGEN | Exit | AGENUS INC | $0 | – | -900,000 | – | -0.42% | – |
| AGRX | Exit | AGILE THERAPEUTICS INC | $0 | – | -1,020,011 | – | -0.46% | – |
| NEPT | Exit | NEPTUNE TECHNOLOGIES AND BIORESOURCES | $0 | – | -6,750,444 | – | -0.46% | – |
| DVAX | Exit | DYNAVAX TECHNOLOGIES CORP SHS PUT 12 12/16/2016put | $0 | – | -16,000 | – | -0.46% | – |
| AKBA | Exit | AKEBIA THERAPEUTICS INC | $0 | – | -809,096 | – | -0.47% | – |
| ACHN | Exit | ACHILLION PHARMACEUTICALS | $0 | – | -929,290 | – | -0.49% | – |
| PSDV | Exit | PSIVIDA CORP | $0 | – | -2,552,431 | – | -0.50% | – |
| AVXS | Exit | AVEXIS INC | $0 | – | -190,000 | – | -0.50% | – |
| ABEO | Exit | ABEONA THERAPEUTICS INC | $0 | – | -1,336,050 | – | -0.52% | – |
| ABMD | Exit | ABIOMED INC | $0 | – | -63,290 | – | -0.52% | – |
| PFNX | Exit | PFENEX INC | $0 | – | -939,930 | – | -0.54% | – |
| FWP | Exit | FORWARD PHARMA A/S-ADRdepository receipt | $0 | – | -404,472 | – | -0.55% | – |
| FPRX | Exit | FIVE PRIME THERAPEUTICS INC | $0 | – | -166,509 | – | -0.56% | – |
| CDTX | Exit | CIDARA THERAPEUTICS INC | $0 | – | -773,369 | – | -0.57% | – |
| Exit | ANI PHARMACEUTICALS INCnote 3.000% | $0 | – | -7,500,000 | – | -0.60% | – | |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -107,000 | – | -0.60% | – |
| QURE | Exit | UNIQURE NV | $0 | – | -1,312,836 | – | -0.65% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -634,894 | – | -0.67% | – |
| VBIV | Exit | VBI VACCINES INC | $0 | – | -3,058,433 | – | -0.68% | – |
| EVH | Exit | EVOLENT HEALTH INC CLASS A | $0 | – | -428,284 | – | -0.68% | – |
| CLSD | Exit | CLEARSIDE BIOMEDICAL INC | $0 | – | -634,801 | – | -0.71% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -430,000 | – | -0.71% | – |
| DERM | Exit | DERMIRA INC | $0 | – | -331,610 | – | -0.72% | – |
| ZYNE | Exit | ZYNERBA PHARMACEUTICALS INC | $0 | – | -868,897 | – | -0.73% | – |
| NERV | Exit | MINERVA NEUROSCIENCES INC | $0 | – | -810,537 | – | -0.74% | – |
| Exit | CYTOMX THERAPEUTICS, INCpreferred stock | $0 | – | -742,021 | – | -0.75% | – | |
| FOMX | Exit | FOAMIX PHARMACEUTICALS LTD | $0 | – | -1,373,284 | – | -0.82% | – |
| ALDR | Exit | ALDER BIOPHARMACEUTICALS INC | $0 | – | -391,280 | – | -0.83% | – |
| DEPO | Exit | DEPOMED INC | $0 | – | -535,000 | – | -0.86% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -460,024 | – | -0.88% | – |
| ARDX | Exit | ARDELYX INC | $0 | – | -1,057,257 | – | -0.88% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INC | $0 | – | -1,940,458 | – | -0.98% | – |
| AERI | Exit | AERIE PHARMACEUTICALS INC | $0 | – | -406,771 | – | -0.99% | – |
| DXCM | Exit | DEXCOM INC | $0 | – | -178,849 | – | -1.01% | – |
| KDMN | Exit | KADMON INC | $0 | – | -2,209,657 | – | -1.05% | – |
| FLML | Exit | FLAMEL TECHNOLOGIES -SP ADRdepository receipt | $0 | – | -1,363,711 | – | -1.09% | – |
| RDUS | Exit | RADIUS HEALTH INC | $0 | – | -313,502 | – | -1.10% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -1,282,286 | – | -1.16% | – |
| CRBP | Exit | CORBUS PHARMACEUTICALS HOLDINGS | $0 | – | -2,701,023 | – | -1.18% | – |
| DBVT | Exit | DBV TECHNOLOGIES SA-SPON ADRdepository receipt | $0 | – | -563,268 | – | -1.32% | – |
| QTNT | Exit | QUOTIENT LTD | $0 | – | -2,671,794 | – | -1.35% | – |
| ACRX | Exit | ACELRX PHARMACEUTICALS INC | $0 | – | -5,408,728 | – | -1.36% | – |
| CLCD | Exit | COLUCID PHARMACEUTICALS INC | $0 | – | -552,030 | – | -1.36% | – |
| XLRN | Exit | ACCELERON PHARMA INC | $0 | – | -589,890 | – | -1.38% | – |
| WVE | Exit | WAVE LIFE SCIENCES LTD | $0 | – | -683,448 | – | -1.43% | – |
| LBIO | Exit | LION BIOTECHNOLOGIES INC | $0 | – | -3,567,553 | – | -1.90% | – |
| LJPC | Exit | LA JOLLA PHARMACEUTICAL COMPANY | $0 | – | -1,323,324 | – | -2.03% | – |
| XNCR | Exit | XENCOR INC | $0 | – | -1,496,229 | – | -2.36% | – |
| NXTM | Exit | NXSTAGE MEDICAL INC | $0 | – | -1,669,703 | – | -2.69% | – |
| VSAR | Exit | VERSARTIS INC | $0 | – | -4,028,685 | – | -3.19% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS INC | $0 | – | -2,334,168 | – | -3.47% | – |
| RTRX | Exit | RETROPHIN INC | $0 | – | -2,446,482 | – | -3.53% | – |
| TSRO | Exit | TESARO INC | $0 | – | -682,415 | – | -4.42% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -14,116,644 | – | -6.74% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -2,476,272 | – | -8.09% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -3,395,236 | – | -13.46% | – |
Q3 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SRPT | Sell | SAREPTA THERAPEUTICS INC | $208,506,000 | +190.2% | 3,395,236 | -9.9% | 13.46% | +170.3% |
| NBIX | Sell | NEUROCRINE BIOSCIENCES INC | $125,398,000 | -1.4% | 2,476,272 | -11.5% | 8.09% | -8.2% |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $104,463,000 | +25.5% | 14,116,644 | -7.4% | 6.74% | +16.9% |
| TSRO | Sell | TESARO INC | $68,405,000 | -28.8% | 682,415 | -40.3% | 4.42% | -33.7% |
| RTRX | Sell | RETROPHIN INC | $54,752,000 | -6.3% | 2,446,482 | -25.4% | 3.53% | -12.7% |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS INC | $53,802,000 | +46.9% | 2,334,168 | +5.7% | 3.47% | +36.8% |
| VSAR | Buy | VERSARTIS INC | $49,351,000 | +57.4% | 4,028,685 | +42.1% | 3.19% | +46.6% |
| NXTM | Buy | NXSTAGE MEDICAL INC | $41,726,000 | +39.2% | 1,669,703 | +20.8% | 2.69% | +29.6% |
| XNCR | Sell | XENCOR INC | $36,643,000 | +26.2% | 1,496,229 | -2.2% | 2.36% | +17.4% |
| LJPC | Sell | LA JOLLA PHARMACEUTICAL COMPANY | $31,482,000 | +47.6% | 1,323,324 | -0.7% | 2.03% | +37.5% |
| LBIO | Sell | LION BIOTECHNOLOGIES INC | $29,360,000 | +0.4% | 3,567,553 | -1.2% | 1.90% | -6.6% |
| WVE | Buy | WAVE LIFE SCIENCES LTD | $22,191,000 | +105.2% | 683,448 | +30.8% | 1.43% | +90.9% |
| XLRN | Sell | ACCELERON PHARMA INC | $21,348,000 | +4.2% | 589,890 | -2.2% | 1.38% | -3.0% |
| CLCD | New | COLUCID PHARMACEUTICALS INC | $21,060,000 | – | 552,030 | – | 1.36% | – |
| ACRX | Sell | ACELRX PHARMACEUTICALS INC | $21,040,000 | +30.4% | 5,408,728 | -9.8% | 1.36% | +21.5% |
| QTNT | Buy | QUOTIENT LTD | $20,893,000 | +19.9% | 2,671,794 | +18.8% | 1.35% | +11.7% |
| DBVT | Buy | DBV TECHNOLOGIES SA-SPON ADRdepository receipt | $20,464,000 | +14.8% | 563,268 | +3.0% | 1.32% | +6.9% |
| CRBP | Sell | CORBUS PHARMACEUTICALS HOLDINGS | $18,339,000 | +91.7% | 2,701,023 | -15.6% | 1.18% | +78.6% |
| RGNX | Buy | REGENXBIO INC | $17,964,000 | +104.3% | 1,282,286 | +16.7% | 1.16% | +90.2% |
| RDUS | New | RADIUS HEALTH INC | $16,957,000 | – | 313,502 | – | 1.10% | – |
| FLML | New | FLAMEL TECHNOLOGIES -SP ADRdepository receipt | $16,910,000 | – | 1,363,711 | – | 1.09% | – |
| KDMN | New | KADMON INC | $16,218,000 | – | 2,209,657 | – | 1.05% | – |
| DXCM | Buy | DEXCOM INC | $15,678,000 | +57.9% | 178,849 | +42.9% | 1.01% | +47.1% |
| AERI | New | AERIE PHARMACEUTICALS INC | $15,352,000 | – | 406,771 | – | 0.99% | – |
| ARDX | New | ARDELYX INC | $13,680,000 | – | 1,057,257 | – | 0.88% | – |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $13,662,000 | +45.3% | 460,024 | -0.9% | 0.88% | +35.3% |
| DEPO | Sell | DEPOMED INC | $13,370,000 | +14.0% | 535,000 | -10.8% | 0.86% | +6.2% |
| ALDR | New | ALDER BIOPHARMACEUTICALS INC | $12,822,000 | – | 391,280 | – | 0.83% | – |
| FOMX | Buy | FOAMIX PHARMACEUTICALS LTD | $12,717,000 | +151.9% | 1,373,284 | +72.7% | 0.82% | +134.6% |
| New | CYTOMX THERAPEUTICS, INCpreferred stock | $11,634,000 | – | 742,021 | – | 0.75% | – | |
| ZYNE | Buy | ZYNERBA PHARMACEUTICALS INC | $11,339,000 | +94.9% | 868,897 | +2.3% | 0.73% | +81.6% |
| DERM | Sell | DERMIRA INC | $11,215,000 | -17.0% | 331,610 | -28.2% | 0.72% | -22.7% |
| ACRS | New | ACLARIS THERAPEUTICS INC | $11,012,000 | – | 430,000 | – | 0.71% | – |
| CLSD | Sell | CLEARSIDE BIOMEDICAL INC | $11,013,000 | +147.5% | 634,801 | -0.0% | 0.71% | +130.8% |
| EVH | Sell | EVOLENT HEALTH INC CLASS A | $10,544,000 | -37.1% | 428,284 | -50.9% | 0.68% | -41.4% |
| VBIV | New | VBI VACCINES INC | $10,490,000 | – | 3,058,433 | – | 0.68% | – |
| MYOK | Buy | MYOKARDIA INC | $10,374,000 | +66.4% | 634,894 | +26.2% | 0.67% | +55.1% |
| QURE | Sell | UNIQURE NV | $10,043,000 | +1.5% | 1,312,836 | -2.2% | 0.65% | -5.5% |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $9,331,000 | -16.6% | 107,000 | -17.7% | 0.60% | -22.3% |
| CDTX | Sell | CIDARA THERAPEUTICS INC | $8,855,000 | +8.3% | 773,369 | -2.5% | 0.57% | +0.9% |
| FPRX | Sell | FIVE PRIME THERAPEUTICS INC | $8,740,000 | +24.8% | 166,509 | -1.7% | 0.56% | +16.0% |
| FWP | Buy | FORWARD PHARMA A/S-ADRdepository receipt | $8,494,000 | +50.1% | 404,472 | +29.9% | 0.55% | +39.8% |
| PFNX | Sell | PFENEX INC | $8,412,000 | +4.6% | 939,930 | -2.2% | 0.54% | -2.7% |
| ABMD | New | ABIOMED INC | $8,138,000 | – | 63,290 | – | 0.52% | – |
| ABEO | Sell | ABEONA THERAPEUTICS INC | $8,016,000 | +92.7% | 1,336,050 | -24.2% | 0.52% | +79.5% |
| AVXS | Buy | AVEXIS INC | $7,830,000 | +13400.0% | 190,000 | +12441.3% | 0.50% | +12525.0% |
| PSDV | Sell | PSIVIDA CORP | $7,683,000 | +1.9% | 2,552,431 | -4.2% | 0.50% | -5.2% |
| ACHN | New | ACHILLION PHARMACEUTICALS | $7,527,000 | – | 929,290 | – | 0.49% | – |
| AKBA | Sell | AKEBIA THERAPEUTICS INC | $7,295,000 | +9.1% | 809,096 | -9.5% | 0.47% | +1.7% |
| DVAX | New | DYNAVAX TECHNOLOGIES CORP SHS PUT 12 12/16/2016put | $7,180,000 | – | 16,000 | – | 0.46% | – |
| AGRX | Buy | AGILE THERAPEUTICS INC | $7,120,000 | +81.9% | 1,020,011 | +98.3% | 0.46% | +69.7% |
| AGEN | New | AGENUS INC | $6,462,000 | – | 900,000 | – | 0.42% | – |
| CSU | Sell | CAPITAL SENIOR LIVING CORP | $6,305,000 | -39.1% | 375,306 | -36.0% | 0.41% | -43.3% |
| ARWR | New | ARROWHEAD PHARMACEUTICALS INC | $6,228,000 | – | 847,458 | – | 0.40% | – |
| XENE | Buy | XENON PHARMACEUTICALS INC | $6,179,000 | +142.0% | 762,800 | +76.2% | 0.40% | +125.4% |
| CLVS | New | CLOVIS ONCOLOGY INC | $6,183,000 | – | 171,500 | – | 0.40% | – |
| SUPN | Sell | SUPERNUS PHARMACEUTICALS INC | $6,048,000 | +18.8% | 244,550 | -2.2% | 0.39% | +10.5% |
| HSGX | New | HISTOGENCIS CORP | $5,706,000 | – | 1,777,777 | – | 0.37% | – |
| ASMB | New | ASSEMBLY BIOSCIENCES INC | $5,606,000 | – | 777,669 | – | 0.36% | – |
| PTI | Buy | PROTEOSTASIS THERAPEUTICS INC | $5,372,000 | +77.1% | 344,550 | +37.8% | 0.35% | +65.2% |
| ADMA | New | ADMA BIOLOGICS INC | $5,327,000 | – | 734,793 | – | 0.34% | – |
| ONS | Sell | ONCOBIOLOGICS INC | $5,308,000 | +18.9% | 1,248,990 | -4.9% | 0.34% | +11.0% |
| AMRN | New | AMARIN CORP PLC-ADRdepository receipt | $5,175,000 | – | 1,622,280 | – | 0.33% | – |
| SELB | Sell | SELECTA BIOSCIENCES INC | $4,961,000 | -21.2% | 348,150 | -22.6% | 0.32% | -26.6% |
| Sell | NEURODERM LTD | $4,883,000 | +11.3% | 264,114 | -2.2% | 0.32% | +3.6% | |
| ANTH | Sell | ANTHERA PHARMACEUTICALS INC | $4,598,000 | -0.3% | 1,459,627 | -2.2% | 0.30% | -7.2% |
| CLLS | Sell | CELLECTIS ADRdepository receipt | $4,323,000 | -11.4% | 179,506 | -2.2% | 0.28% | -17.5% |
| CEMP | Buy | CEMPRA INC | $4,247,000 | +51.5% | 175,503 | +3.2% | 0.27% | +41.2% |
| AGTC | Sell | APPLIED GENETIC TECHNOLOGIES | $4,167,000 | -55.2% | 426,048 | -35.3% | 0.27% | -58.3% |
| BGNE | New | BEIGENE LTDdepository receipt | $4,069,000 | – | 132,057 | – | 0.26% | – |
| MYL | Buy | MYLAN NV | $3,610,000 | +1571.3% | 94,711 | +1794.2% | 0.23% | +1453.3% |
| INNL | Sell | INNOCOLL HOLDINGS PLC | $3,221,000 | +14.7% | 547,792 | -2.2% | 0.21% | +6.7% |
| OPHT | New | OPHTHOTECH CORP CALL 80 12/16/2016call | $2,740,000 | – | 600,000 | – | 0.18% | – |
| APVO | New | APTEVO THERAPEUTICS INC | $2,530,000 | – | 988,133 | – | 0.16% | – |
| PRTO | Sell | PROTEON THERAPEUTICS INC | $2,510,000 | +13.7% | 269,005 | -2.2% | 0.16% | +5.9% |
| MGCD | Sell | MGC DIAGNOSTICS CORP | $2,275,000 | +3.7% | 329,733 | -1.9% | 0.15% | -3.3% |
| NEOS | Sell | NEOS THERAPEUTICS INC | $2,175,000 | -52.8% | 330,593 | -47.3% | 0.14% | -56.2% |
| RXDX | Sell | IGNYTA INC | $2,137,000 | -9.4% | 339,727 | -21.9% | 0.14% | -15.9% |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $2,075,000 | – | 65,240 | – | 0.13% | – |
| ARNI | New | ARNO THERAPEUTICS INC | $1,963,000 | – | 4,177,577 | – | 0.13% | – |
| ABT | New | ABBOTT LABORATORIES | $1,946,000 | – | 46,019 | – | 0.13% | – |
| EIGR | Buy | EIGER BIOPHARMACEUTICALS INC | $1,739,000 | -16.4% | 129,920 | +23.8% | 0.11% | -22.2% |
| CBPO | Sell | CHINA BIOLOGIC PRODUCTS INC | $1,705,000 | +14.6% | 13,695 | -2.2% | 0.11% | +6.8% |
| MDGN | Sell | MEDGENICS INC | $1,635,000 | -1.8% | 293,460 | -2.2% | 0.11% | -7.8% |
| BIO | New | BIO RAD LABORATORIES CLASS A | $1,638,000 | – | 10,000 | – | 0.11% | – |
| VCRA | New | VOCERA COMMUNICATIONS INC | $1,593,000 | – | 94,236 | – | 0.10% | – |
| ALQA | New | ALLIQUA BIOMEDICAL INC | $1,537,000 | – | 1,921,951 | – | 0.10% | – |
| VCEL | Sell | VERICEL CORP | $1,526,000 | +21.7% | 544,996 | -2.2% | 0.10% | +13.8% |
| NVRO | Sell | NEVRO CORP | $1,226,000 | -95.4% | 11,746 | -96.8% | 0.08% | -95.8% |
| NVLS | Sell | NIVALIS THERAPEUTICS INC | $994,000 | +72.9% | 122,275 | -2.2% | 0.06% | +60.0% |
| BCLI | New | BRAINSTORM CELL THERAPEUTICS | $964,000 | – | 400,000 | – | 0.06% | – |
| ATRS | New | ANTARES PHARMA INC | $912,000 | – | 0 | – | 0.06% | – |
| ONSIZ | Buy | ONCOBIOLOGICS INC*w exp 2/18/2017 | $787,000 | +289.6% | 656,382 | +41.9% | 0.05% | +264.3% |
| ANIP | Sell | ANI PHARMACEUTICALS INC | $767,000 | -79.5% | 11,561 | -82.8% | 0.05% | -80.8% |
| SCYX | Sell | SCYNEXIS INC | $662,000 | +74.2% | 171,185 | -2.2% | 0.04% | +65.4% |
| AGLE | Sell | AEGLEA BIOTHERAPEUTICS INC | $664,000 | +28.9% | 103,585 | -2.2% | 0.04% | +19.4% |
| BIIB | New | BIOGEN INC | $601,000 | – | 1,921 | – | 0.04% | – |
| HRC | New | HILL ROM HOLDINGS INC | $593,000 | – | 9,563 | – | 0.04% | – |
| IMDZ | New | IMMUNE DESIGN CORP | $589,000 | – | 77,725 | – | 0.04% | – |
| HWAY | New | HEALTHWAYS INC | $572,000 | – | 21,608 | – | 0.04% | – |
| INCR | New | INC RESEARCH HOLDINGS INC CLASS A | $563,000 | – | 12,636 | – | 0.04% | – |
| ICLR | New | ICON INC | $532,000 | – | 6,873 | – | 0.03% | – |
| HUM | New | HUMANA INC CALL 190 04/21/2017call | $526,000 | – | 400 | – | 0.03% | – |
| INCY | New | INCYTE CORP | $530,000 | – | 5,619 | – | 0.03% | – |
| MOH | Sell | MOLINA HEALTHCARE INC | $518,000 | +12.9% | 8,879 | -3.5% | 0.03% | +3.1% |
| A | New | AGILENT TECHNOLOGIES INC | $496,000 | – | 10,540 | – | 0.03% | – |
| SGYPQ | New | SYNERGY PHARMACEUTICALS INC | $491,000 | – | 89,127 | – | 0.03% | – |
| PBYI | New | PUMA BIOTECHNOLOGY INC | $492,000 | – | 7,344 | – | 0.03% | – |
| AMAG | New | AMAG PHARMACEUTICALS INC | $479,000 | – | 19,524 | – | 0.03% | – |
| LNTH | New | LANTHEUS HOLDINGS INC | $445,000 | – | 53,763 | – | 0.03% | – |
| AMSG | New | AMSURG CORP | $444,000 | – | 6,618 | – | 0.03% | – |
| AFAM | New | ALMOST FAMILY INC | $439,000 | – | 11,942 | – | 0.03% | – |
| AMN | New | AMN HEALTHCARE INC | $428,000 | – | 13,445 | – | 0.03% | – |
| ANTM | New | ANTHEM INC | $426,000 | – | 3,400 | – | 0.03% | – |
| Q | New | QUINTILES IMS HOLDINGS INC | $414,000 | – | 5,103 | – | 0.03% | – |
| ACHI | New | ACCRETIVE HEALTH INC | $305,000 | – | 125,000 | – | 0.02% | – |
| ONSIW | Buy | ONCOBIOLOGICS INC*w exp 2/18/2017 | $313,000 | +47.6% | 656,382 | +41.9% | 0.02% | +33.3% |
| MNKKQ | New | MALLINCKRODT PLC | $314,000 | – | 4,500 | – | 0.02% | – |
| MACK | Sell | MERRIMACK PHARMACEUTICALS INC | $311,000 | +15.2% | 48,910 | -2.2% | 0.02% | +5.3% |
| TDOC | New | TELADOC INC | $275,000 | – | 15,000 | – | 0.02% | – |
| GNVC | Sell | GENVEC INC | $259,000 | -92.5% | 561,320 | -7.5% | 0.02% | -92.9% |
| PMD | New | PSYCHEMEDICS CORP | $250,000 | – | 12,626 | – | 0.02% | – |
| LLY | New | ELI LILLY & CO CALL 90 01/20/2017call | $250,000 | – | 1,000 | – | 0.02% | – |
| BVX | New | BOVIE MEDICAL CORP | $253,000 | – | 48,544 | – | 0.02% | – |
| NTLA | Sell | INTELLIA THERAPEUTICS INC | $250,000 | -21.9% | 14,673 | -2.2% | 0.02% | -27.3% |
| NSTG | New | NANOSTRING TECHNOLOGIES INC | $210,000 | – | 10,518 | – | 0.01% | – |
| ZGNX | New | ZOGENIX INC | $212,000 | – | 18,541 | – | 0.01% | – |
| GKOS | Buy | GLAUKOS CORP | $200,000 | +2122.2% | 5,300 | +1666.7% | 0.01% | +1200.0% |
| CGNT | Sell | COGENTIX MEDICAL INC | $180,000 | -63.9% | 99,008 | -80.9% | 0.01% | -65.7% |
| LHCG | New | LHC GROUP INC | $175,000 | – | 4,745 | – | 0.01% | – |
| NUVA | New | NUVASIVE INC | $173,000 | – | 2,589 | – | 0.01% | – |
| MTD | New | METTLER TOLEDO INTERNATIONAL | $174,000 | – | 415 | – | 0.01% | – |
| ARAY | New | ACCURAY INC | $174,000 | – | 27,300 | – | 0.01% | – |
| AMRI | New | ALBANY MOLECULAR RESEARCH | $170,000 | – | 10,300 | – | 0.01% | – |
| MDSO | New | MEDIDATA SOLUTIONS INC | $160,000 | – | 2,865 | – | 0.01% | – |
| ISRG | New | INTUITIVE SURGICAL INC | $145,000 | – | 200 | – | 0.01% | – |
| IVC | New | INVACARE CORP | $147,000 | – | 13,200 | – | 0.01% | – |
| BOLD | New | AUDENTES THERAPEUTICS INC | $134,000 | – | 7,500 | – | 0.01% | – |
| ATRC | New | ATRICURE INC | $126,000 | – | 7,949 | – | 0.01% | – |
| HNGR | New | HANGER INC | $128,000 | – | 15,038 | – | 0.01% | – |
| STML | Sell | STEMLINE THERAPEUTICS INC | $116,000 | -78.2% | 10,702 | -86.4% | 0.01% | -81.1% |
| ACETQ | New | ACETO CORP | $115,000 | – | 6,054 | – | 0.01% | – |
| CYNO | New | CYNOSURE INC CLASS A | $92,000 | – | 1,800 | – | 0.01% | – |
| PPHM | Sell | PEREGRINE PHARMACEUTICALS | $10,000 | -87.7% | 24,332 | -89.2% | 0.00% | -83.3% |
| BMRN | New | BIOMARIN PHARMACEUTICAL INC | $23,000 | – | 250 | – | 0.00% | – |
| DSCI | Sell | DERMA SCIENCES INC | $14,000 | -99.2% | 2,970 | -99.3% | 0.00% | -99.2% |
| IMMU | Sell | IMMUNOMEDICS INC | $17,000 | -96.7% | 5,343 | -97.6% | 0.00% | -97.2% |
| AVGR | New | AVINGER INC | $5,000 | – | 1,062 | – | 0.00% | – |
| SGMO | New | SANGAMO BIOSCIENCES INC | $1,000 | – | 272 | – | 0.00% | – |
| EGRX | Buy | EAGLE PHARMACEUTICALS INC | $3,000 | -100.0% | 544,770 | +81.6% | 0.00% | -100.0% |
| MD | New | MEDNAX INC | $2,000 | – | 29 | – | 0.00% | – |
| VYGR | Exit | VOYAGER THERAPEUTICS INC | $0 | – | -650 | – | 0.00% | – |
| ZIOP | Exit | ZIOPHARM ONCOLOGY INC | $0 | – | -1,000 | – | 0.00% | – |
| CRY | New | CRYOLIFE INC | $2,000 | – | 123 | – | 0.00% | – |
| Exit | AVINGER INC | $0 | – | -1,062 | – | -0.00% | – | |
| DVAX | Exit | DYNAVAX TECHNOLOGIES CORP | $0 | – | -2,499 | – | -0.00% | – |
| BTX | Exit | BIOTIME INC | $0 | – | -13,740 | – | -0.00% | – |
| JUNO | Exit | JUNO THERAPEUTICS INC | $0 | – | -1,113 | – | -0.00% | – |
| MCRB | Exit | SERES THERAPEUTICS INC | $0 | – | -1,540 | – | -0.00% | – |
| Exit | ATARA BIOTHERAPEUTICS INC | $0 | – | -2,500 | – | -0.00% | – | |
| CORT | Exit | CORCEPT THERAPEUTICS INC | $0 | – | -11,000 | – | -0.00% | – |
| IMGN | Exit | IMMUNOGEN INC | $0 | – | -25,745 | – | -0.01% | – |
| ZLTQ | Exit | ZELTIQ AESTHETICS INC | $0 | – | -2,638 | – | -0.01% | – |
| AIMT | Exit | AIMMUNE THERAPEUTICS INC | $0 | – | -6,448 | – | -0.01% | – |
| DPLO | Exit | DIPLOMAT PHARMACY INC | $0 | – | -2,175 | – | -0.01% | – |
| HLF | Exit | HERBALIFE LTD | $0 | – | -1,250 | – | -0.01% | – |
| GNCA | Exit | GENOCEA BIOSCIENCES INC | $0 | – | -17,313 | – | -0.01% | – |
| ABBV | Exit | ABBVIE INC | $0 | – | -1,250 | – | -0.01% | – |
| Exit | ABBOTT LABS | $0 | – | -3,040 | – | -0.01% | – | |
| NVAX | Exit | NOVAVAX INC | $0 | – | -32,000 | – | -0.02% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -71,124 | – | -0.02% | – |
| CNC | Exit | CENTENE CORP DEL | $0 | – | -4,948 | – | -0.02% | – |
| OPHT | Exit | OPHTHOTECH CORP | $0 | – | -8,145 | – | -0.03% | – |
| Exit | ANTHEM INC | $0 | – | -3,400 | – | -0.03% | – | |
| Exit | ALMOST FAMILY INC | $0 | – | -11,942 | – | -0.04% | – | |
| Exit | AMN HEALTHCARE SERVICES INC | $0 | – | -13,445 | – | -0.04% | – | |
| LXRX | Exit | Lexicon Pharmaceuticals Inc | $0 | – | -50,000 | – | -0.05% | – |
| LPCN | Exit | LIPOCINE INCput | $0 | – | -284,400 | – | -0.06% | – |
| LPCN | Exit | LIPOCINE INCcall | $0 | – | -300,000 | – | -0.06% | – |
| BCLI | Exit | BRAINSTROM CELL THERAPEUTICS | $0 | – | -400,000 | – | -0.07% | – |
| Exit | ARNO THERAPEUTIC INC | $0 | – | -3,463,292 | – | -0.08% | – | |
| GMED | Exit | GLOBUS MED INCcl a | $0 | – | -50,000 | – | -0.08% | – |
| Exit | ABIOMED INC | $0 | – | -14,700 | – | -0.11% | – | |
| PETX | Exit | ARATANA THERAPEUTICS INC | $0 | – | -256,500 | – | -0.11% | – |
| RLYP | Exit | RELYPSA INCput | $0 | – | -100,000 | – | -0.13% | – |
| PGNX | Exit | PROGENICS PHARMACEUTICALSput | $0 | – | -500,000 | – | -0.15% | – |
| Exit | ALLIQUA BIOMEDICAL INC | $0 | – | -1,921,951 | – | -0.15% | – | |
| IONS | Exit | Ionis Pharmaceuticals Ord Shsput | $0 | – | -100,000 | – | -0.16% | – |
| Exit | ADMA BIOLOGICS INC | $0 | – | -398,394 | – | -0.16% | – | |
| Exit | ARDELYX INC | $0 | – | -315,955 | – | -0.19% | – | |
| TKAI | Exit | TOKAI PHARMACEUTICALS INC | $0 | – | -661,041 | – | -0.25% | – |
| TSRO | Exit | TESARO INCput | $0 | – | -50,000 | – | -0.29% | – |
| Exit | ASSEMBLY BIOSCIENCES INC | $0 | – | -795,000 | – | -0.31% | – | |
| ADHD | Exit | ALCOBRA LTD | $0 | – | -1,028,272 | – | -0.32% | – |
| Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -165,240 | – | -0.37% | – | |
| AXGT | Exit | AXOVANT SCIENCES LTD | $0 | – | -485,000 | – | -0.43% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -742,021 | – | -0.52% | – |
| TEVA | Exit | TEVA PHARMACEUTICAL INDS LTDadr | $0 | – | -196,000 | – | -0.68% | – |
| Exit | ALDER BIOPHARMACEUTICALS INC | $0 | – | -400,000 | – | -0.69% | – | |
| HEDJ | Exit | WISDOMTREE EUROPE HEDGED EQUput | $0 | – | -200,000 | – | -0.70% | – |
| VBIV | Exit | VBI VACCINES INC | $0 | – | -3,058,433 | – | -0.84% | – |
| STJ | Exit | ST JUDE MEDICAL | $0 | – | -233,000 | – | -1.26% | – |
| SRPT | Exit | Sarepta Therapeutics Inccall | $0 | – | -979,200 | – | -1.30% | – |
| CPXX | Exit | CELATOR PHARMACEUTICALS INC | $0 | – | -838,400 | – | -1.75% | – |
| XBI | Exit | STREETTRACKS SPDR BIOTEC ETFput | $0 | – | -500,000 | – | -1.88% | – |
| MDVN | Exit | MEDIVATION INC | $0 | – | -760,000 | – | -3.18% | – |
| SRPT | Exit | Sarepta Therapeutics Incput | $0 | – | -7,619,300 | – | -10.07% | – |
Q2 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SRPT | New | Sarepta Therapeutics Incput | $145,300,000 | – | 7,619,300 | – | 10.07% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $127,167,000 | – | 2,797,967 | – | 8.82% | – |
| TSRO | New | TESARO INC | $96,121,000 | – | 1,143,615 | – | 6.66% | – |
| FOLD | New | AMICUS | $83,207,000 | – | 15,239,444 | – | 5.77% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $71,843,000 | – | 3,767,316 | – | 4.98% | – |
| RTRX | New | Retrophin Inc | $58,405,000 | – | 3,279,380 | – | 4.05% | – |
| MDVN | New | MEDIVATION INC | $45,828,000 | – | 760,000 | – | 3.18% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $36,625,000 | – | 2,207,668 | – | 2.54% | – |
| VSAR | New | VERSARTIS INC | $31,363,000 | – | 2,835,754 | – | 2.17% | – |
| NXTM | New | NXSTAGE MEDICAL INC | $29,971,000 | – | 1,382,410 | – | 2.08% | – |
| LBIO | New | LION BIOTECHNOLOGIES INC | $29,257,000 | – | 3,611,976 | – | 2.03% | – |
| XNCR | New | XENCOR INC | $29,046,000 | – | 1,529,574 | – | 2.01% | – |
| XBI | New | STREETTRACKS SPDR BIOTEC ETFput | $27,045,000 | – | 500,000 | – | 1.88% | – |
| NVRO | New | NEVRO CORP | $26,939,000 | – | 365,229 | – | 1.87% | – |
| CPXX | New | CELATOR PHARMACEUTICALS INC | $25,303,000 | – | 838,400 | – | 1.75% | – |
| LJPC | New | LA JOLLA PHARMACEUTICAL CO | $21,325,000 | – | 1,332,815 | – | 1.48% | – |
| XLRN | New | ACCELERON | $20,491,000 | – | 603,036 | – | 1.42% | – |
| SRPT | New | Sarepta Therapeutics Inccall | $18,673,000 | – | 979,200 | – | 1.30% | – |
| STJ | New | ST JUDE MEDICAL | $18,174,000 | – | 233,000 | – | 1.26% | – |
| DBVT | New | DBV TECHNOLOGIES S Asponsored adr | $17,833,000 | – | 546,696 | – | 1.24% | – |
| QTNT | New | QUOTIENT LTD | $17,430,000 | – | 2,249,067 | – | 1.21% | – |
| EVH | New | EVOLENT HEALTH INCcl a | $16,763,000 | – | 873,064 | – | 1.16% | – |
| ACRX | New | ACELRX PHARMA | $16,129,000 | – | 5,995,760 | – | 1.12% | – |
| DERM | New | DERMIRA INC | $13,514,000 | – | 462,000 | – | 0.94% | – |
| VBIV | New | VBI VACCINES INC | $12,080,000 | – | 3,058,433 | – | 0.84% | – |
| DEPO | New | DEPOMED INC | $11,727,000 | – | 600,000 | – | 0.81% | – |
| EGRX | New | EAGLE PHARMACEUTICALS INC | $11,637,000 | – | 300,000 | – | 0.81% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $11,183,000 | – | 130,000 | – | 0.78% | – |
| ALDX | New | ALDEYRA | $11,041,000 | – | 1,940,458 | – | 0.76% | – |
| WVE | New | WAVE LIFE SCIENCES LTD | $10,812,000 | – | 522,595 | – | 0.75% | – |
| CSU | New | CAPITAL SR LIVING CORP | $10,357,000 | – | 586,136 | – | 0.72% | – |
| HEDJ | New | WISDOMTREE EUROPE HEDGED EQUput | $10,106,000 | – | 200,000 | – | 0.70% | – |
| New | ALDER BIOPHARMACEUTICALS INC | $9,988,000 | – | 400,000 | – | 0.69% | – | |
| DXCM | New | DEXCOM INC | $9,930,000 | – | 125,174 | – | 0.69% | – |
| QURE | New | UNIQURE NV | $9,891,000 | – | 1,342,093 | – | 0.69% | – |
| TEVA | New | TEVA PHARMACEUTICAL INDS LTDadr | $9,845,000 | – | 196,000 | – | 0.68% | – |
| CRBP | New | CORBUS PHARMACEUTICALS HLDGS | $9,568,000 | – | 3,200,000 | – | 0.66% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $9,404,000 | – | 464,404 | – | 0.65% | – |
| AGTC | New | APPLIED GENETIC TECHNOL CORP | $9,309,000 | – | 658,851 | – | 0.64% | – |
| RGNX | New | REGENXBIO INC | $8,793,000 | – | 1,099,213 | – | 0.61% | – |
| NERV | New | MINERVA NEUROSCIENCES INC | $8,275,000 | – | 810,537 | – | 0.57% | – |
| CDTX | New | CIDARA THERAPEUTICS INC | $8,174,000 | – | 792,857 | – | 0.57% | – |
| New | ANI PHARMACEUTICALS INCnote 3.000%12/ | $8,121,000 | – | 7,500,000 | – | 0.56% | – | |
| PFNX | New | PFENEX INC | $8,043,000 | – | 960,877 | – | 0.56% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $7,579,000 | – | 742,021 | – | 0.52% | – |
| PSDV | New | pSivida Corp | $7,542,000 | – | 2,665,000 | – | 0.52% | – |
| FPRX | New | FIVE PRIME THERAPEUTICS INC | $7,006,000 | – | 169,439 | – | 0.49% | – |
| NEPT | New | NEPTUNE TECHNOLOGIES BIORESO | $6,885,000 | – | 6,750,444 | – | 0.48% | – |
| AKBA | New | AKEBIA THERAPEUTICS INC | $6,684,000 | – | 893,600 | – | 0.46% | – |
| SELB | New | SELECTA BIOSCIENCES INC | $6,296,000 | – | 450,000 | – | 0.44% | – |
| AXGT | New | AXOVANT SCIENCES LTD | $6,227,000 | – | 485,000 | – | 0.43% | – |
| MYOK | New | MYOKARDIA INC | $6,235,000 | – | 502,894 | – | 0.43% | – |
| ZYNE | New | ZYNERBA PHARMACEUTICALS INC | $5,818,000 | – | 849,350 | – | 0.40% | – |
| FWP | New | FORWARD PHARMA A/Ssponsored adr | $5,658,000 | – | 311,400 | – | 0.39% | – |
| New | ACADIA PHARMACEUTICALS INC | $5,364,000 | – | 165,240 | – | 0.37% | – | |
| SUPN | New | SUPERNUS PHARMACEUTICALS INC | $5,093,000 | – | 250,000 | – | 0.35% | – |
| FOMX | New | FOAMIX PHARMACEUTICALS LTD | $5,048,000 | – | 795,000 | – | 0.35% | – |
| CLLS | New | CELLECTIS S Asponsored ads | $4,879,000 | – | 183,507 | – | 0.34% | – |
| ANTH | New | ANTHERA PHARMACEUTICALS INC | $4,611,000 | – | 1,492,156 | – | 0.32% | – |
| ADHD | New | ALCOBRA LTD | $4,617,000 | – | 1,028,272 | – | 0.32% | – |
| NEOS | New | NEOS THERAPEUTICS INC | $4,611,000 | – | 626,876 | – | 0.32% | – |
| ONS | New | ONCOBIOLOGICS INC | $4,463,000 | – | 1,312,763 | – | 0.31% | – |
| CLSD | New | CLEARSIDE BIOMEDICAL INC | $4,450,000 | – | 634,808 | – | 0.31% | – |
| New | ASSEMBLY BIOSCIENCES INC | $4,412,000 | – | 795,000 | – | 0.31% | – | |
| New | NEURODERM LTD | $4,388,000 | – | 270,000 | – | 0.30% | – | |
| TSRO | New | TESARO INCput | $4,203,000 | – | 50,000 | – | 0.29% | – |
| ABEO | New | Abeona Therapeutics Inc | $4,159,000 | – | 1,762,881 | – | 0.29% | – |
| AGRX | New | AGILE THERAPEUTICS INC | $3,914,000 | – | 514,288 | – | 0.27% | – |
| ANIP | New | ANI PHARMACEUTICALS INC | $3,749,000 | – | 67,161 | – | 0.26% | – |
| TKAI | New | TOKAI PHARMACEUTICALS INC | $3,642,000 | – | 661,041 | – | 0.25% | – |
| GNVC | New | GENVEC INC | $3,447,000 | – | 606,644 | – | 0.24% | – |
| CASC | New | Cascadian Therapeutics Inc | $3,220,000 | – | 3,414,121 | – | 0.22% | – |
| PTI | New | PROTEOSTASIS THERAPEUTICS IN | $3,033,000 | – | 250,000 | – | 0.21% | – |
| AVEO | New | AVEO PHARMACEUTICALS INC | $2,987,000 | – | 3,108,808 | – | 0.21% | – |
| INNL | New | INNOCOLL HLDGS PLC | $2,808,000 | – | 560,000 | – | 0.20% | – |
| CEMP | New | CEMPRA INC | $2,803,000 | – | 170,000 | – | 0.19% | – |
| New | ARDELYX INC | $2,758,000 | – | 315,955 | – | 0.19% | – | |
| XENE | New | XENON PHARMACEUTICALS INC | $2,553,000 | – | 432,800 | – | 0.18% | – |
| New | ADMA BIOLOGICS INC | $2,371,000 | – | 398,394 | – | 0.16% | – | |
| RXDX | New | IGNYTA INC | $2,359,000 | – | 435,260 | – | 0.16% | – |
| IONS | New | Ionis Pharmaceuticals Ord Shsput | $2,329,000 | – | 100,000 | – | 0.16% | – |
| PRTO | New | PROTEON THERAPEUTICS INC | $2,208,000 | – | 275,000 | – | 0.15% | – |
| MGCD | New | MGC DIAGNOSTICS CORP | $2,193,000 | – | 336,287 | – | 0.15% | – |
| New | ALLIQUA BIOMEDICAL INC | $2,152,000 | – | 1,921,951 | – | 0.15% | – | |
| PGNX | New | PROGENICS PHARMACEUTICALSput | $2,110,000 | – | 500,000 | – | 0.15% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $2,079,000 | – | 104,920 | – | 0.14% | – |
| RLYP | New | RELYPSA INCput | $1,850,000 | – | 100,000 | – | 0.13% | – |
| AFMD | New | AFFIMED N V | $1,821,000 | – | 734,301 | – | 0.13% | – |
| DSCI | New | DERMA SCIENCES INC | $1,706,000 | – | 432,884 | – | 0.12% | – |
| MDGN | New | MEDGENICS INC | $1,665,000 | – | 300,000 | – | 0.12% | – |
| PETX | New | ARATANA THERAPEUTICS INC | $1,621,000 | – | 256,500 | – | 0.11% | – |
| New | ABIOMED INC | $1,607,000 | – | 14,700 | – | 0.11% | – | |
| CBPO | New | CHINA BIOLOGIC PRODS INC | $1,488,000 | – | 14,000 | – | 0.10% | – |
| VCEL | New | VERICEL CORP | $1,254,000 | – | 557,342 | – | 0.09% | – |
| GMED | New | GLOBUS MED INCcl a | $1,192,000 | – | 50,000 | – | 0.08% | – |
| New | ARNO THERAPEUTIC INC | $1,080,000 | – | 3,463,292 | – | 0.08% | – | |
| ABEOW | New | ABEONA THERAPEUTICS INC*w exp 12/19/201 | $1,071,000 | – | 1,259,636 | – | 0.07% | – |
| BCLI | New | BRAINSTROM CELL THERAPEUTICS | $964,000 | – | 400,000 | – | 0.07% | – |
| LPCN | New | LIPOCINE INCcall | $912,000 | – | 300,000 | – | 0.06% | – |
| LPCN | New | LIPOCINE INCput | $865,000 | – | 284,400 | – | 0.06% | – |
| PZRXQ | New | PHASERX INC | $852,000 | – | 200,000 | – | 0.06% | – |
| CSBR | New | CHAMPIONS ONCOLOGY INC | $801,000 | – | 372,597 | – | 0.06% | – |
| LXRX | New | Lexicon Pharmaceuticals Inc | $718,000 | – | 50,000 | – | 0.05% | – |
| LCI | New | LANNET INC | $634,000 | – | 26,670 | – | 0.04% | – |
| MGLN | New | MAGELLAN HEALTH INC | $577,000 | – | 8,772 | – | 0.04% | – |
| NVLS | New | NIVALIS THERAPEUTICS INC | $575,000 | – | 125,000 | – | 0.04% | – |
| MCK | New | MCKESSON CORP | $556,000 | – | 2,979 | – | 0.04% | – |
| AET | New | AETNA INC NEW | $544,000 | – | 4,454 | – | 0.04% | – |
| WCG | New | WELLCARE HEALTH PLANS INC | $542,000 | – | 5,056 | – | 0.04% | – |
| WOOF | New | VCA INC | $537,000 | – | 7,940 | – | 0.04% | – |
| UHS | New | UNIVERSAL HLTH SVCS INCcl b | $535,000 | – | 3,989 | – | 0.04% | – |
| New | AMN HEALTHCARE SERVICES INC | $537,000 | – | 13,445 | – | 0.04% | – | |
| VWR | New | VWR CORP | $539,000 | – | 18,657 | – | 0.04% | – |
| STML | New | STEMLINE THERAPEUTICS INC | $532,000 | – | 78,603 | – | 0.04% | – |
| LH | New | LABORATORY CORP AMER HLDGS | $520,000 | – | 3,990 | – | 0.04% | – |
| IMMU | New | IMMUNOMEDICS INC | $514,000 | – | 221,700 | – | 0.04% | – |
| ABC | New | AMERISOURCEBERGEN CORP | $516,000 | – | 6,500 | – | 0.04% | – |
| AGLE | New | AEGLEA BIOTHERAPEUTICS INC | $515,000 | – | 105,893 | – | 0.04% | – |
| New | ALMOST FAMILY INC | $509,000 | – | 11,942 | – | 0.04% | – | |
| CAH | New | CARDINAL HEALTH INC | $499,000 | – | 6,398 | – | 0.04% | – |
| CGNT | New | COGENTIX MED INC | $498,000 | – | 517,760 | – | 0.04% | – |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $503,000 | – | 4,753 | – | 0.04% | – |
| KND | New | KINDRED HEALTHCARE INC | $478,000 | – | 42,301 | – | 0.03% | – |
| HCA | New | HCA HOLDINGS INC | $478,000 | – | 6,202 | – | 0.03% | – |
| MOH | New | MOLINA HEALTHCARE INC | $459,000 | – | 9,200 | – | 0.03% | – |
| UNH | New | UNITEDHEALTH GROUP INC | $456,000 | – | 3,231 | – | 0.03% | – |
| PAHC | New | PHIBRO ANIMAL HEALTH CORP | $453,000 | – | 24,300 | – | 0.03% | – |
| CRL | New | CHARLES RIV LABS INTL INC | $452,000 | – | 5,482 | – | 0.03% | – |
| New | ANTHEM INC | $447,000 | – | 3,400 | – | 0.03% | – | |
| THC | New | TENET HEALTHCARE CORP | $448,000 | – | 16,200 | – | 0.03% | – |
| SCMP | New | SUCAMPO PHARMACEUTICALS INCcl a | $451,000 | – | 41,096 | – | 0.03% | – |
| OPHT | New | OPHTHOTECH CORP | $416,000 | – | 8,145 | – | 0.03% | – |
| ENZ | New | ENZO BIOCHEM INC | $401,000 | – | 67,113 | – | 0.03% | – |
| FCAU | New | FIAT CHRYSLER AUTOMOBILES N | $379,000 | – | 62,000 | – | 0.03% | – |
| SCYX | New | SCYNEXIS INC | $380,000 | – | 175,000 | – | 0.03% | – |
| CNC | New | CENTENE CORP DEL | $353,000 | – | 4,948 | – | 0.02% | – |
| ACST | New | ACASTI PHARMA INCcl a new | $336,000 | – | 236,559 | – | 0.02% | – |
| NTLA | New | INTELLIA THERAPEUTICS INC | $320,000 | – | 15,000 | – | 0.02% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $312,000 | – | 71,124 | – | 0.02% | – |
| MACK | New | MERRIMACK PHARMACEUTICALS IN | $270,000 | – | 50,000 | – | 0.02% | – |
| RACE | New | FERRARI N V | $254,000 | – | 6,200 | – | 0.02% | – |
| NVAX | New | NOVAVAX INC | $233,000 | – | 32,000 | – | 0.02% | – |
| MYL | New | MYLAN N V | $216,000 | – | 5,000 | – | 0.02% | – |
| ONSIW | New | ONCOBIOLOGICS INC*w exp 02/18/201 | $212,000 | – | 462,500 | – | 0.02% | – |
| ONSIZ | New | ONCOBIOLOGICS INC*w exp 05/18/201 | $202,000 | – | 462,500 | – | 0.01% | – |
| New | PERNIX THERAPEUTICS HLDGS INdbcv 4.250% 4/0 | $200,000 | – | 1,000,000 | – | 0.01% | – | |
| DRAD | New | DIGIRAD CORP | $129,000 | – | 24,988 | – | 0.01% | – |
| New | ABBOTT LABS | $120,000 | – | 3,040 | – | 0.01% | – | |
| PPHM | New | PEREGRINE PHARMACEUTICALS IN | $81,000 | – | 224,332 | – | 0.01% | – |
| ABBV | New | ABBVIE INC | $77,000 | – | 1,250 | – | 0.01% | – |
| GNCA | New | GENOCEA BIOSCIENCES INC | $71,000 | – | 17,313 | – | 0.01% | – |
| IMGN | New | IMMUNOGEN INC | $79,000 | – | 25,745 | – | 0.01% | – |
| ZLTQ | New | ZELTIQ AESTHETICS INC | $72,000 | – | 2,638 | – | 0.01% | – |
| HLF | New | HERBALIFE LTD | $73,000 | – | 1,250 | – | 0.01% | – |
| AIMT | New | AIMMUNE THERAPEUTICS INC | $70,000 | – | 6,448 | – | 0.01% | – |
| DPLO | New | DIPLOMAT PHARMACY INC | $76,000 | – | 2,175 | – | 0.01% | – |
| AVXS | New | AVEXIS INC | $58,000 | – | 1,515 | – | 0.00% | – |
| New | ATARA BIOTHERAPEUTICS INC | $56,000 | – | 2,500 | – | 0.00% | – | |
| CORT | New | CORCEPT THERAPEUTICS INC | $60,000 | – | 11,000 | – | 0.00% | – |
| JUNO | New | JUNO THERAPEUTICS INC | $43,000 | – | 1,113 | – | 0.00% | – |
| MCRB | New | SERES THERAPEUTICS INC | $45,000 | – | 1,540 | – | 0.00% | – |
| BTX | New | BIOTIME INC | $36,000 | – | 13,740 | – | 0.00% | – |
| DVAX | New | DYNAVAX TECHNOLOGIES CORP | $36,000 | – | 2,499 | – | 0.00% | – |
| New | AVINGER INC | $13,000 | – | 1,062 | – | 0.00% | – | |
| New | SEVION THERAPEUTICS | $12,000 | – | 59,220 | – | 0.00% | – | |
| GKOS | New | GLAUKOS CORP | $9,000 | – | 300 | – | 0.00% | – |
| CAPR | New | CAPRICOR THERAPEUTICS INC | $16,000 | – | 4,000 | – | 0.00% | – |
| VYGR | New | VOYAGER THERAPEUTICS INC | $7,000 | – | 650 | – | 0.00% | – |
| TNGNQ | New | TENGION INC | $1,000 | – | 1,826,399 | – | 0.00% | – |
| NPCUF | New | ALLON THERAPEUTICS | $0 | – | 751,124 | – | 0.00% | – |
| FLKS | New | FLEX PHARMA INC | $2,000 | – | 237 | – | 0.00% | – |
| INGN | New | INOGEN INC | $6,000 | – | 125 | – | 0.00% | – |
| ZIOP | New | ZIOPHARM ONCOLOGY INC | $5,000 | – | 1,000 | – | 0.00% | – |
Q4 2015
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CNAT | Exit | CONATUS PHARMACEUTICALS INC | $0 | – | -850 | – | 0.00% | – |
| IDRA | Exit | IDERA PHARMACEUTICALS INC | $0 | – | -3,074 | – | 0.00% | – |
| XBI | Exit | STREETTRACKS SPDR BIOTEC ETFcall | $0 | – | -200 | – | 0.00% | – |
| NUVA | Exit | NUVASIVE INC | $0 | – | -504 | – | -0.00% | – |
| CAPR | Exit | CAPRICOR THERAPEUTICS INC | $0 | – | -8,000 | – | -0.00% | – |
| VRX | Exit | VALEANT PHARMACEUTICALS INTERNATIONAL INcall | $0 | – | -200 | – | -0.00% | – |
| JNP | Exit | JUNIPER PHARMACEUTICALS INC | $0 | – | -3,472 | – | -0.00% | – |
| NSPH | Exit | NANOSPHERE INC | $0 | – | -70,758 | – | -0.01% | – |
| ELGX | Exit | ENDOLOGIX INC | $0 | – | -11,510 | – | -0.01% | – |
| MYGN | Exit | MYRIAD GENETICS INC | $0 | – | -5,000 | – | -0.01% | – |
| AMAG | Exit | AMAG PHARMACEUTICALS INC | $0 | – | -5,808 | – | -0.01% | – |
| DVCR | Exit | DIVERSICARE HEALTHCARE SVCS | $0 | – | -24,674 | – | -0.01% | – |
| REPH | Exit | RECRO PHARMA INC | $0 | – | -24,126 | – | -0.01% | – |
| SCMP | Exit | SUCAMPO PHARMACEUTICALS INCcl a | $0 | – | -15,810 | – | -0.01% | – |
| LCI | Exit | LANNET INC | $0 | – | -8,096 | – | -0.01% | – |
| Exit | AMGEN INC | $0 | – | -2,560 | – | -0.01% | – | |
| INFI | Exit | INFINITY PHARMACEUTICALS INC | $0 | – | -40,000 | – | -0.01% | – |
| LPNT | Exit | LIFEPOINT HEALTH INC | $0 | – | -5,044 | – | -0.01% | – |
| MGLN | Exit | MAGELLAN HEALTH INC | $0 | – | -6,820 | – | -0.02% | – |
| GTS | Exit | TRIPLE-S MGMT CORPcl b | $0 | – | -21,210 | – | -0.02% | – |
| CBM | Exit | CAMBREX CORP | $0 | – | -9,384 | – | -0.02% | – |
| WCG | Exit | WELLCARE HEALTH PLANS INC | $0 | – | -4,378 | – | -0.02% | – |
| ICLR | Exit | ICON PLC | $0 | – | -5,262 | – | -0.02% | – |
| CNCE | Exit | CONCERT PHARMACEUTICALS INC | $0 | – | -20,758 | – | -0.02% | – |
| CRIS | Exit | CURIS INC | $0 | – | -200,000 | – | -0.02% | – |
| Exit | ANTHEM INC | $0 | – | -2,872 | – | -0.02% | – | |
| PMC | Exit | PHARMERICA CORP | $0 | – | -13,600 | – | -0.02% | – |
| MOH | Exit | MOLINA HEALTHCARE INC | $0 | – | -5,776 | – | -0.02% | – |
| HCA | Exit | HCA HOLDINGS INC | $0 | – | -5,126 | – | -0.02% | – |
| CAH | Exit | CARDINAL HEALTH INC | $0 | – | -5,148 | – | -0.02% | – |
| EW | Exit | EDWARDS LIFESCIENCES CORP | $0 | – | -3,000 | – | -0.02% | – |
| TARO | Exit | TARO PHARMACEUTICAL INDS LTD | $0 | – | -2,986 | – | -0.02% | – |
| HNT | Exit | HEALTH NET INC | $0 | – | -7,662 | – | -0.02% | – |
| Exit | ADDUS HOMECARE CORP | $0 | – | -15,202 | – | -0.02% | – | |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -4,914 | – | -0.02% | – |
| GB | Exit | GREATBATCH INC | $0 | – | -8,782 | – | -0.02% | – |
| PSDV | Exit | PSIVIDA CORP | $0 | – | -630,000 | – | -0.02% | – |
| LHCG | Exit | LHC GROUP INC | $0 | – | -11,834 | – | -0.02% | – |
| INCR | Exit | INC RESH HLDGS INCcl a | $0 | – | -14,522 | – | -0.02% | – |
| NVO | Exit | NOVO-NORDISK A Sadr | $0 | – | -10,680 | – | -0.02% | – |
| AET | Exit | AETNA INC NEW | $0 | – | -5,172 | – | -0.02% | – |
| APHB | Exit | AMPLIPHI BIOSCIENCES | $0 | – | -160,000 | – | -0.02% | – |
| BVX | Exit | BOVIE MEDICAL CORP | $0 | – | -325,400 | – | -0.03% | – |
| Exit | ACHAOGEN INC | $0 | – | -120,000 | – | -0.03% | – | |
| OTIC | Exit | OTONOMY INC | $0 | – | -370,736 | – | -0.03% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -60,000 | – | -0.03% | – | |
| DRNA | Exit | DICERNA PHARMACEUTICALS INC | $0 | – | -100,000 | – | -0.03% | – |
| QTNTW | Exit | QUOTIENT LTD*w exp 10/30/201 | $0 | – | -262,502 | – | -0.04% | – |
| TBT | Exit | PROSHARES TR | $0 | – | -24,000 | – | -0.04% | – |
| SNSS | Exit | SUNESIS PHARMACEUTICALS INC | $0 | – | -1,400,000 | – | -0.04% | – |
| GLMD | Exit | GALMED PHARMACEUTICALS LTD | $0 | – | -150,000 | – | -0.04% | – |
| XNCR | Exit | XENCOR INCput | $0 | – | -100,000 | – | -0.05% | – |
| ACST | Exit | ACASTI PHARMA INC | $0 | – | -4,731,200 | – | -0.05% | – |
| STML | Exit | STEMLINE THERAPEUTICS INC | $0 | – | -157,206 | – | -0.06% | – |
| Exit | ARNO THERAPEUTICS INC | $0 | – | -4,069,442 | – | -0.06% | – | |
| ANIP | Exit | ANI PHARMACEUTICALS INC | $0 | – | -38,512 | – | -0.06% | – |
| FCAU | Exit | FIAT CHRYSLER AUTOMOBILES N | $0 | – | -124,000 | – | -0.06% | – |
| AQXP | Exit | AQUINOX PHARMACEUTICALS INC | $0 | – | -119,200 | – | -0.07% | – |
| CGNT | Exit | COGENTIX MED INC | $0 | – | -1,346,514 | – | -0.07% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -40,000 | – | -0.07% | – |
| IRWD | Exit | IRONWOOD PHARMACEUTICALS INC | $0 | – | -172,458 | – | -0.07% | – |
| BCLI | Exit | BRAINSTORM CELL THERAPEUTICS | $0 | – | -800,000 | – | -0.07% | – |
| VCEL | Exit | VERICEL CORP | $0 | – | -702,324 | – | -0.08% | – |
| XIV | Exit | CREDIT SUISSE NASSAU BRHinvrs vix sterm | $0 | – | -93,000 | – | -0.09% | – |
| SGYPQ | Exit | SYNERGY PHARMACEUTICALS DEL | $0 | – | -452,000 | – | -0.10% | – |
| NVTA | Exit | INVITAE CORP | $0 | – | -336,666 | – | -0.10% | – |
| SCYX | Exit | SCYNEXIS INC | $0 | – | -350,000 | – | -0.10% | – |
| ONTY | Exit | ONCOTHYREON INC | $0 | – | -7,093,794 | – | -0.11% | – |
| UUP | Exit | POWERSHS DB US DOLLAR INDEXdoll indx bull | $0 | – | -110,000 | – | -0.11% | – |
| BCRX | Exit | BIOCRYST PHARMACEUTICALS | $0 | – | -247,490 | – | -0.11% | – |
| GNVC | Exit | GENVEC INC | $0 | – | -1,231,688 | – | -0.11% | – |
| Exit | AVINGER INC | $0 | – | -195,000 | – | -0.12% | – | |
| NVLS | Exit | NIVALIS THERAPEUTICS INC | $0 | – | -250,000 | – | -0.13% | – |
| RPRX | Exit | REPROS THERAPEUTICS INC | $0 | – | -440,000 | – | -0.13% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -411,600 | – | -0.14% | – |
| DSCI | Exit | DERMA SCIENCES INC | $0 | – | -721,168 | – | -0.14% | – |
| Exit | INTEC PHARMA LTD JERUSALEM | $0 | – | -700,000 | – | -0.16% | – | |
| Exit | BAXTER INTL INC | $0 | – | -120,000 | – | -0.16% | – | |
| CRBP | Exit | CORBUS PHARMACEUTICALS INC | $0 | – | -2,500,000 | – | -0.16% | – |
| CSBR | Exit | CHAMPIONS ONCOLOGY INC | $0 | – | -745,194 | – | -0.16% | – |
| ABEOW | Exit | ABEONA THERAPEUTICS INC*w exp 12/19/201 | $0 | – | -2,519,272 | – | -0.17% | – |
| EVH | Exit | EVOLENT HEALTH INCcl a | $0 | – | -274,578 | – | -0.18% | – |
| VTAE | Exit | VITAE PHARMACEUTICALS INC | $0 | – | -400,000 | – | -0.18% | – |
| MGCD | Exit | MGC DIAGNOSTICS CORP | $0 | – | -672,574 | – | -0.18% | – |
| AKBA | Exit | AKEBIA THERAPEUTICS INC | $0 | – | -520,000 | – | -0.20% | – |
| CPRX | Exit | CATALYST PHARMACEUTICALS INC | $0 | – | -1,702,400 | – | -0.20% | – |
| CI | Exit | CIGNA CORPORATION | $0 | – | -38,940 | – | -0.21% | – |
| ARIA | Exit | ARIAD PHARMACEUTICALS INC | $0 | – | -900,000 | – | -0.21% | – |
| PTCT | Exit | PTC THERAPEUTICS INCcall | $0 | – | -200,000 | – | -0.21% | – |
| RGEN | Exit | REPLIGEN CORPput | $0 | – | -200,000 | – | -0.22% | – |
| WBA | Exit | WALGREENS BOOTS ALLIANCE INC | $0 | – | -70,584 | – | -0.23% | – |
| CYAD | Exit | CELYAD SAadr | $0 | – | -150,000 | – | -0.25% | – |
| STJ | Exit | ST JUDE MED INC | $0 | – | -103,040 | – | -0.26% | – |
| HEWG | Exit | ISHARES TRhdg msci germn | $0 | – | -290,000 | – | -0.26% | – |
| PRTO | Exit | PROTEON THERAPEUTICS INC | $0 | – | -550,000 | – | -0.31% | – |
| TRXC | Exit | TRANSENTERIX INC | $0 | – | -3,652,864 | – | -0.33% | – |
| NERV | Exit | MINVERA NEUROSCIENCES | $0 | – | -1,621,074 | – | -0.34% | – |
| FPRX | Exit | FIVE PRIME THERAPEUTICS INC | $0 | – | -568,258 | – | -0.35% | – |
| RLYP | Exit | RELYPSA INCput | $0 | – | -500,000 | – | -0.37% | – |
| TKAI | Exit | TOKAI PHARMACEUTICALS INC | $0 | – | -970,676 | – | -0.40% | – |
| ANTH | Exit | ANTHERA PHARMACEUTICALS INC | $0 | – | -1,984,312 | – | -0.42% | – |
| AXGT | Exit | AXOVANT SCIENCES LTD | $0 | – | -820,000 | – | -0.42% | – |
| AFMD | Exit | AFFIMED N V | $0 | – | -1,737,240 | – | -0.43% | – |
| THOR | Exit | THORATEC CORP | $0 | – | -172,000 | – | -0.44% | – |
| Exit | ARDELYX INC | $0 | – | -631,910 | – | -0.44% | – | |
| RLYP | Exit | RELYPSA INCcall | $0 | – | -600,000 | – | -0.44% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INC | $0 | – | -1,914,386 | – | -0.45% | – |
| Exit | NEURODERM LTD | $0 | – | -540,000 | – | -0.45% | – | |
| AGTC | Exit | APPLIED GENETIC TECHNOL CORP | $0 | – | -1,701,984 | – | -0.45% | – |
| CLLS | Exit | CELLECTIS S Asponsored ads | $0 | – | -437,358 | – | -0.46% | – |
| Exit | ALLIQUA BIOMEDICAL INC | $0 | – | -3,843,902 | – | -0.49% | – | |
| THOR | Exit | THORATEC CORPcall | $0 | – | -200,000 | – | -0.51% | – |
| XLRN | Exit | ACCELERON PHARMA INC | $0 | – | -552,072 | – | -0.55% | – |
| Exit | ANI PHARMACEUTICALS INCnote 3.000%12/0 | $0 | – | -15,000,000 | – | -0.55% | – | |
| ABEO | Exit | ABEONA THERAPEUTICS INC | $0 | – | -3,525,762 | – | -0.57% | – |
| NEPT | Exit | NEPTUNE TECHNOLOGIES BIORESO | $0 | – | -13,400,888 | – | -0.59% | – |
| Exit | BELLICUM PHARMACEUTICALS INC | $0 | – | -1,042,376 | – | -0.60% | – | |
| Exit | ASSEMBLY BIOSCIENCES INC | $0 | – | -1,590,000 | – | -0.61% | – | |
| NEOS | Exit | NEOS THERAPEUTICS INC | $0 | – | -742,132 | – | -0.62% | – |
| ZYNE | Exit | ZYNERBA PHARMACEUTICALS INC | $0 | – | -1,158,700 | – | -0.66% | – |
| SHPG | Exit | SHIRE PLCsponsored adr | $0 | – | -82,000 | – | -0.67% | – |
| VBIV | Exit | VBI VACCINES INC | $0 | – | -6,520,712 | – | -0.69% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -808,808 | – | -0.69% | – |
| TEVA | Exit | TEVA PHARMACEUTICAL INDS LTDadr | $0 | – | -320,000 | – | -0.72% | – |
| EGRX | Exit | EAGLE PHARMACEUTICALS INC | $0 | – | -246,088 | – | -0.73% | – |
| CDTX | Exit | CIDARA THERAPEUTICS INC | $0 | – | -1,485,716 | – | -0.76% | – |
| SRPT | Exit | Sarepta Therapeutics Inccall | $0 | – | -600,000 | – | -0.77% | – |
| Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -590,480 | – | -0.78% | – | |
| GILD | Exit | GILEAD SCIENCES INCput | $0 | – | -200,000 | – | -0.78% | – |
| QTNT | Exit | QUOTIENT LTD | $0 | – | -1,553,606 | – | -0.83% | – |
| NVO | Exit | NOVO-NORDISK A/S-SPONS ADRput | $0 | – | -400,000 | – | -0.87% | – |
| DBVT | Exit | DBV TECHNOLOGIES S Asponsored adr | $0 | – | -613,430 | – | -0.87% | – |
| DERM | Exit | DERMIRA INC | $0 | – | -944,000 | – | -0.88% | – |
| CSU | Exit | CAPITAL SR LIVING CORP | $0 | – | -1,107,200 | – | -0.89% | – |
| SSO | Exit | PROSHARES ULTRA S & P500put | $0 | – | -400,000 | – | -0.89% | – |
| QURE | Exit | UNIQURE NV | $0 | – | -1,380,538 | – | -1.13% | – |
| PFNX | Exit | PFENEX INC | $0 | – | -1,942,086 | – | -1.16% | – |
| CEMP | Exit | CEMPRA INC | $0 | – | -1,165,000 | – | -1.30% | – |
| RXDX | Exit | IGNYTA INC | $0 | – | -3,863,200 | – | -1.36% | – |
| LBIO | Exit | LION BIOTECHNOLOGIES INC | $0 | – | -5,910,912 | – | -1.36% | – |
| XBI | Exit | STREETTRACKS SPDR BIOTEC ETFput | $0 | – | -550,000 | – | -1.37% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -1,558,426 | – | -1.37% | – |
| LJPC | Exit | LA JOLLA PHARMACEUTICAL CO | $0 | – | -1,309,030 | – | -1.45% | – |
| RLYP | Exit | RELYPSA INC | $0 | – | -1,975,884 | – | -1.46% | – |
| ACRX | Exit | ACELRX PHARMACEUTICALS INC | $0 | – | -12,528,120 | – | -1.53% | – |
| XNCR | Exit | XENCOR INC | $0 | – | -3,509,568 | – | -1.72% | – |
| IWM | Exit | ISHARES RUSSELL 2000put | $0 | – | -400,000 | – | -1.74% | – |
| VSAR | Exit | VERSARTIS INC | $0 | – | -4,635,908 | – | -2.14% | – |
| PTCT | Exit | PTC THERAPEUTICS INCput | $0 | – | -2,010,000 | – | -2.14% | – |
| GWPH | Exit | GW PHARMACEUTICALS -ADRput | $0 | – | -600,000 | – | -2.19% | – |
| NVRO | Exit | NEVRO CORP | $0 | – | -1,213,622 | – | -2.25% | – |
| DYAX | Exit | DYAX CORP | $0 | – | -3,292,630 | – | -2.51% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -1,843,600 | – | -3.10% | – |
| TSRO | Exit | TESARO INC | $0 | – | -1,963,518 | – | -3.15% | – |
| RTRX | Exit | RETROPHIN INC | $0 | – | -5,294,160 | – | -4.28% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -5,569,856 | – | -7.15% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -5,885,934 | – | -9.36% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -28,878,888 | – | -14.03% | – |
Q3 2015
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FOLD | Buy | AMICUS THERAPEUTICS INC | $351,266,000 | +71.9% | 28,878,888 | +100.0% | 14.03% | +14.1% |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $234,202,000 | +49.3% | 5,885,934 | +79.2% | 9.36% | -0.9% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $178,848,000 | +109.2% | 5,569,856 | +98.2% | 7.15% | +38.8% |
| RTRX | Buy | RETROPHIN INC | $107,258,000 | +17.0% | 5,294,160 | +87.7% | 4.28% | -22.4% |
| TSRO | Buy | TESARO INC | $78,736,000 | +60.3% | 1,963,518 | +135.1% | 3.15% | +6.4% |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $77,726,000 | – | 1,843,600 | – | 3.10% | – |
| DYAX | Buy | DYAX CORP | $62,856,000 | +32.8% | 3,292,630 | +84.3% | 2.51% | -11.9% |
| NVRO | Buy | NEVRO CORP | $56,300,000 | +31.1% | 1,213,622 | +51.9% | 2.25% | -13.0% |
| GWPH | New | GW PHARMACEUTICALS -ADRput | $54,822,000 | – | 600,000 | – | 2.19% | – |
| PTCT | New | PTC THERAPEUTICS INCput | $53,668,000 | – | 2,010,000 | – | 2.14% | – |
| VSAR | Buy | VERSARTIS INC | $53,452,000 | +165.8% | 4,635,908 | +250.8% | 2.14% | +76.4% |
| IWM | New | ISHARES RUSSELL 2000put | $43,680,000 | – | 400,000 | – | 1.74% | – |
| XNCR | Buy | XENCOR INC | $42,922,000 | +3.7% | 3,509,568 | +86.2% | 1.72% | -31.2% |
| ACRX | Buy | ACELRX PHARMACEUTICALS INC | $38,210,000 | +37.1% | 12,528,120 | +90.6% | 1.53% | -9.1% |
| RLYP | Buy | RELYPSA INC | $36,574,000 | -3.0% | 1,975,884 | +73.5% | 1.46% | -35.6% |
| LJPC | Buy | LA JOLLA PHARMACEUTICAL CO | $36,378,000 | +486.8% | 1,309,030 | +417.6% | 1.45% | +289.5% |
| RGNX | New | REGENXBIO INC | $34,332,000 | – | 1,558,426 | – | 1.37% | – |
| XBI | Buy | STREETTRACKS SPDR BIOTEC ETFput | $34,238,000 | -9.5% | 550,000 | +266.7% | 1.37% | -39.9% |
| LBIO | Buy | LION BIOTECHNOLOGIES INC | $34,046,000 | +34.5% | 5,910,912 | +114.2% | 1.36% | -10.8% |
| RXDX | Buy | IGNYTA INC | $33,918,000 | +14.2% | 3,863,200 | +96.3% | 1.36% | -24.2% |
| CEMP | Buy | CEMPRA INC | $32,434,000 | +64.9% | 1,165,000 | +103.5% | 1.30% | +9.4% |
| PFNX | Buy | PFENEX INC | $29,150,000 | +48.6% | 1,942,086 | +92.1% | 1.16% | -1.4% |
| QURE | Buy | UNIQURE NV | $28,232,000 | +60.8% | 1,380,538 | +112.3% | 1.13% | +6.7% |
| SSO | Buy | PROSHARES ULTRA S & P500put | $22,240,000 | +589.2% | 400,000 | +700.0% | 0.89% | +358.2% |
| CSU | Buy | CAPITAL SR LIVING CORP | $22,200,000 | +41.5% | 1,107,200 | +72.9% | 0.89% | -6.1% |
| DERM | Buy | DERMIRA INC | $22,032,000 | +725.8% | 944,000 | +521.1% | 0.88% | +446.6% |
| DBVT | Buy | DBV TECHNOLOGIES S Asponsored adr | $21,832,000 | +24430.3% | 613,430 | +20334.0% | 0.87% | +17340.0% |
| NVO | New | NOVO-NORDISK A/S-SPONS ADRput | $21,696,000 | – | 400,000 | – | 0.87% | – |
| QTNT | Buy | QUOTIENT LTD | $20,694,000 | +141.3% | 1,553,606 | +176.2% | 0.83% | +60.3% |
| Buy | ACADIA PHARMACEUTICALS INC | $19,528,000 | +13.7% | 590,480 | +43.9% | 0.78% | -24.6% | |
| SRPT | Buy | Sarepta Therapeutics Inccall | $19,268,000 | +26.6% | 600,000 | +20.0% | 0.77% | -15.9% |
| CDTX | Buy | CIDARA THERAPEUTICS INC | $18,898,000 | +349.3% | 1,485,716 | +395.2% | 0.76% | +198.4% |
| EGRX | Buy | EAGLE PHARMACEUTICALS INC | $18,218,000 | -3.3% | 246,088 | +5.6% | 0.73% | -35.9% |
| TEVA | New | TEVA PHARMACEUTICAL INDS LTDadr | $18,068,000 | – | 320,000 | – | 0.72% | – |
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $17,258,000 | +61.1% | 808,808 | +100.0% | 0.69% | +7.0% |
| VBIV | Buy | VBI VACCINES INC | $17,214,000 | +152.7% | 6,520,712 | +149.8% | 0.69% | +67.8% |
| SHPG | Buy | SHIRE PLCsponsored adr | $16,830,000 | +74.2% | 82,000 | +105.0% | 0.67% | +15.5% |
| ZYNE | New | ZYNERBA PHARMACEUTICALS INC | $16,580,000 | – | 1,158,700 | – | 0.66% | – |
| NEOS | New | NEOS THERAPEUTICS INC | $15,592,000 | – | 742,132 | – | 0.62% | – |
| Buy | ASSEMBLY BIOSCIENCES INC | $15,200,000 | +0.5% | 1,590,000 | +102.6% | 0.61% | -33.3% | |
| Buy | BELLICUM PHARMACEUTICALS INC | $15,144,000 | +28.8% | 1,042,376 | +88.6% | 0.60% | -14.5% | |
| NEPT | Buy | NEPTUNE TECHNOLOGIES BIORESO | $14,740,000 | +70.5% | 13,400,888 | +100.0% | 0.59% | +13.3% |
| ABEO | Buy | ABEONA THERAPEUTICS INC | $14,280,000 | +500.5% | 3,525,762 | +650.2% | 0.57% | +299.3% |
| Buy | ANI PHARMACEUTICALS INCnote 3.000%12/0 | $13,846,000 | +63.1% | 15,000,000 | +100.0% | 0.55% | +8.2% | |
| XLRN | Buy | ACCELERON PHARMA INC | $13,746,000 | +57.4% | 552,072 | +100.0% | 0.55% | +4.4% |
| THOR | Buy | THORATEC CORPcall | $12,654,000 | +183.9% | 200,000 | +100.0% | 0.51% | +88.8% |
| Buy | ALLIQUA BIOMEDICAL INC | $12,184,000 | +20.3% | 3,843,902 | +100.0% | 0.49% | -20.2% | |
| CLLS | Buy | CELLECTIS S Asponsored ads | $11,528,000 | +76.0% | 437,358 | +141.0% | 0.46% | +17.0% |
| AGTC | Buy | APPLIED GENETIC TECHNOL CORP | $11,182,000 | +142.2% | 1,701,984 | +465.6% | 0.45% | +60.8% |
| ALDX | Buy | ALDEYRA THERAPEUTICS INC | $11,160,000 | +65.4% | 1,914,386 | +120.1% | 0.45% | +9.9% |
| Buy | NEURODERM LTD | $11,162,000 | +263.6% | 540,000 | +170.0% | 0.45% | +141.1% | |
| RLYP | New | RELYPSA INCcall | $11,106,000 | – | 600,000 | – | 0.44% | – |
| Buy | ARDELYX INC | $10,920,000 | +116.4% | 631,910 | +100.0% | 0.44% | +43.4% | |
| THOR | Sell | THORATEC CORP | $10,880,000 | +8.0% | 172,000 | -23.9% | 0.44% | -28.3% |
| AFMD | Buy | AFFIMED N V | $10,722,000 | -22.3% | 1,737,240 | +69.7% | 0.43% | -48.4% |
| AXGT | Buy | AXOVANT SCIENCES LTD | $10,594,000 | +173.6% | 820,000 | +331.6% | 0.42% | +81.5% |
| ANTH | Buy | ANTHERA PHARMACEUTICALS INC | $10,412,000 | +0.5% | 1,984,312 | +65.1% | 0.42% | -33.3% |
| TKAI | Buy | TOKAI PHARMACEUTICALS INC | $10,048,000 | +55.7% | 970,676 | +100.0% | 0.40% | +3.1% |
| RLYP | New | RELYPSA INCput | $9,256,000 | – | 500,000 | – | 0.37% | – |
| FPRX | Buy | FIVE PRIME THERAPEUTICS INC | $8,746,000 | +57.1% | 568,258 | +153.5% | 0.35% | +4.2% |
| NERV | Buy | MINVERA NEUROSCIENCES | $8,510,000 | +81.0% | 1,621,074 | +100.0% | 0.34% | +20.1% |
| TRXC | Buy | TRANSENTERIX INC | $8,254,000 | +34.6% | 3,652,864 | +78.7% | 0.33% | -10.6% |
| PRTO | Buy | PROTEON THERAPEUTICS INC | $7,650,000 | +55.7% | 550,000 | +100.0% | 0.31% | +3.4% |
| HEWG | Buy | ISHARES TRhdg msci germn | $6,580,000 | +189.9% | 290,000 | +233.3% | 0.26% | +92.0% |
| STJ | New | ST JUDE MED INC | $6,502,000 | – | 103,040 | – | 0.26% | – |
| CYAD | Buy | CELYAD SAadr | $6,278,000 | +60.9% | 150,000 | +100.0% | 0.25% | +6.8% |
| WBA | Buy | WALGREENS BOOTS ALLIANCE INC | $5,866,000 | +96.8% | 70,584 | +100.0% | 0.23% | +30.7% |
| RGEN | New | REPLIGEN CORPput | $5,570,000 | – | 200,000 | – | 0.22% | – |
| PTCT | New | PTC THERAPEUTICS INCcall | $5,340,000 | – | 200,000 | – | 0.21% | – |
| CI | Buy | CIGNA CORPORATION | $5,258,000 | +47.7% | 38,940 | +77.2% | 0.21% | -1.9% |
| ARIA | Buy | ARIAD PHARMACEUTICALS INC | $5,256,000 | +231.2% | 900,000 | +368.9% | 0.21% | +118.8% |
| CPRX | Buy | CATALYST PHARMACEUTICALS INC | $5,108,000 | +45.3% | 1,702,400 | +100.0% | 0.20% | -3.8% |
| AKBA | New | AKEBIA THERAPEUTICS INC | $5,024,000 | – | 520,000 | – | 0.20% | – |
| MGCD | Buy | MGC DIAGNOSTICS CORP | $4,438,000 | +151.9% | 672,574 | +100.0% | 0.18% | +67.0% |
| VTAE | Buy | VITAE PHARMACEUTICALS INC | $4,404,000 | +103.9% | 400,000 | +166.7% | 0.18% | +35.4% |
| EVH | Buy | EVOLENT HEALTH INCcl a | $4,382,000 | +47.0% | 274,578 | +79.7% | 0.18% | -2.2% |
| ABEOW | Buy | ABEONA THERAPEUTICS INC*w exp 12/19/201 | $4,346,000 | +93.2% | 2,519,272 | +101.5% | 0.17% | +28.9% |
| CSBR | New | CHAMPIONS ONCOLOGY INC | $3,986,000 | – | 745,194 | – | 0.16% | – |
| New | BAXTER INTL INC | $3,942,000 | – | 120,000 | – | 0.16% | – | |
| New | INTEC PHARMA LTD JERUSALEM | $3,920,000 | – | 700,000 | – | 0.16% | – | |
| CRBP | Buy | CORBUS PHARMACEUTICALS INC | $3,924,000 | +46.5% | 2,500,000 | +187.4% | 0.16% | -2.5% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $3,398,000 | +31.0% | 411,600 | +82.9% | 0.14% | -12.8% |
| DSCI | Buy | DERMA SCIENCES INC | $3,396,000 | -86.4% | 721,168 | +106.8% | 0.14% | -91.0% |
| RPRX | New | REPROS THERAPEUTICS INC | $3,270,000 | – | 440,000 | – | 0.13% | – |
| NVLS | New | NIVALIS THERAPEUTICS INC | $3,242,000 | – | 250,000 | – | 0.13% | – |
| Buy | AVINGER INC | $2,868,000 | +116.8% | 195,000 | +90.2% | 0.12% | +43.8% | |
| GNVC | Buy | GENVEC INC | $2,846,000 | +126.6% | 1,231,688 | +100.0% | 0.11% | +50.0% |
| BCRX | Sell | BIOCRYST PHARMACEUTICALS | $2,822,000 | -59.8% | 247,490 | -47.3% | 0.11% | -73.3% |
| UUP | Buy | POWERSHS DB US DOLLAR INDEXdoll indx bull | $2,762,000 | +22.6% | 110,000 | +22.2% | 0.11% | -19.1% |
| ONTY | Buy | ONCOTHYREON INC | $2,760,000 | -77.9% | 7,093,794 | +112.0% | 0.11% | -85.4% |
| SCYX | Buy | SCYNEXIS INC | $2,548,000 | +65.7% | 350,000 | +100.0% | 0.10% | +9.7% |
| NVTA | Buy | INVITAE CORP | $2,431,000 | +5.4% | 336,666 | +12.4% | 0.10% | -30.2% |
| SGYPQ | New | SYNERGY PHARMACEUTICALS DEL | $2,396,000 | – | 452,000 | – | 0.10% | – |
| XIV | Buy | CREDIT SUISSE NASSAU BRHinvrs vix sterm | $2,264,000 | +1297.5% | 93,000 | +2225.0% | 0.09% | +800.0% |
| VCEL | Buy | VERICEL CORP | $1,904,000 | +0.9% | 702,324 | +32.8% | 0.08% | -33.3% |
| BCLI | Buy | BRAINSTORM CELL THERAPEUTICS | $1,832,000 | +26.9% | 800,000 | +100.0% | 0.07% | -16.1% |
| IRWD | Sell | IRONWOOD PHARMACEUTICALS INC | $1,798,000 | -69.8% | 172,458 | -65.1% | 0.07% | -79.9% |
| SAGE | Buy | SAGE THERAPEUTICS INC | $1,694,000 | +16.0% | 40,000 | +100.0% | 0.07% | -22.7% |
| CGNT | Buy | COGENTIX MED INC | $1,670,000 | +53.1% | 1,346,514 | +100.0% | 0.07% | +1.5% |
| AQXP | Sell | AQUINOX PHARMACEUTICALS INC | $1,678,000 | +86.0% | 119,200 | -8.3% | 0.07% | +24.1% |
| FCAU | Buy | FIAT CHRYSLER AUTOMOBILES N | $1,638,000 | +81.8% | 124,000 | +100.0% | 0.06% | +20.4% |
| ANIP | Sell | ANI PHARMACEUTICALS INC | $1,522,000 | -92.5% | 38,512 | -88.2% | 0.06% | -95.0% |
| Buy | ARNO THERAPEUTICS INC | $1,424,000 | +16.6% | 4,069,442 | +100.0% | 0.06% | -23.0% | |
| STML | Buy | STEMLINE THERAPEUTICS INC | $1,388,000 | +48.8% | 157,206 | +98.4% | 0.06% | -1.8% |
| ACST | Buy | ACASTI PHARMA INC | $1,252,000 | +68.1% | 4,731,200 | +100.0% | 0.05% | +11.1% |
| XNCR | New | XENCOR INCput | $1,224,000 | – | 100,000 | – | 0.05% | – |
| SNSS | Buy | SUNESIS PHARMACEUTICALS INC | $1,134,000 | -46.2% | 1,400,000 | +100.0% | 0.04% | -64.6% |
| GLMD | Buy | GALMED PHARMACEUTICALS LTD | $1,114,000 | +47.5% | 150,000 | +100.0% | 0.04% | 0.0% |
| TBT | New | PROSHARES TR | $1,040,000 | – | 24,000 | – | 0.04% | – |
| QTNTW | New | QUOTIENT LTD*w exp 10/30/201 | $950,000 | – | 262,502 | – | 0.04% | – |
| DRNA | Buy | DICERNA PHARMACEUTICALS INC | $822,000 | +17.8% | 100,000 | +100.0% | 0.03% | -21.4% |
| Buy | TRILLIUM THERAPEUTICS INC | $782,000 | +19.4% | 60,000 | +100.0% | 0.03% | -20.5% | |
| OTIC | Buy | OTONOMY INC | $728,000 | -91.4% | 370,736 | +0.9% | 0.03% | -94.3% |
| Buy | ACHAOGEN INC | $692,000 | +91.2% | 120,000 | +100.0% | 0.03% | +27.3% | |
| BVX | Buy | BOVIE MEDICAL CORP | $644,000 | +33.6% | 325,400 | +88.4% | 0.03% | -10.3% |
| APHB | New | AMPLIPHI BIOSCIENCES | $632,000 | – | 160,000 | – | 0.02% | – |
| AET | Sell | AETNA INC NEW | $566,000 | -56.0% | 5,172 | -48.7% | 0.02% | -70.1% |
| NVO | Buy | NOVO-NORDISK A Sadr | $580,000 | +353.1% | 10,680 | +356.4% | 0.02% | +187.5% |
| INCR | Buy | INC RESH HLDGS INCcl a | $580,000 | +99.3% | 14,522 | +100.0% | 0.02% | +27.8% |
| LHCG | Buy | LHC GROUP INC | $530,000 | +134.5% | 11,834 | +100.0% | 0.02% | +50.0% |
| PSDV | Buy | PSIVIDA CORP | $514,000 | -56.7% | 630,000 | +100.0% | 0.02% | -70.4% |
| GB | Buy | GREATBATCH INC | $496,000 | +109.3% | 8,782 | +100.0% | 0.02% | +42.9% |
| New | ADDUS HOMECARE CORP | $474,000 | – | 15,202 | – | 0.02% | – | |
| GILD | Buy | GILEAD SCIENCES INC | $482,000 | +67.4% | 4,914 | +100.0% | 0.02% | +11.8% |
| HNT | Buy | HEALTH NET INC | $462,000 | +87.8% | 7,662 | +100.0% | 0.02% | +20.0% |
| TARO | Buy | TARO PHARMACEUTICAL INDS LTD | $426,000 | +98.1% | 2,986 | +100.0% | 0.02% | +30.8% |
| EW | New | EDWARDS LIFESCIENCES CORP | $426,000 | – | 3,000 | – | 0.02% | – |
| CAH | Buy | CARDINAL HEALTH INC | $396,000 | +84.2% | 5,148 | +100.0% | 0.02% | +23.1% |
| PMC | Buy | PHARMERICA CORP | $388,000 | +71.7% | 13,600 | +100.0% | 0.02% | +14.3% |
| CNCE | New | CONCERT PHARMACEUTICALS INC | $390,000 | – | 20,758 | – | 0.02% | – |
| CRIS | New | CURIS INC | $404,000 | – | 200,000 | – | 0.02% | – |
| Buy | ANTHEM INC | $402,000 | +70.3% | 2,872 | +100.0% | 0.02% | +14.3% | |
| HCA | Sell | HCA HOLDINGS INC | $396,000 | -91.4% | 5,126 | -89.9% | 0.02% | -94.2% |
| MOH | Buy | MOLINA HEALTHCARE INC | $398,000 | +96.1% | 5,776 | +100.0% | 0.02% | +33.3% |
| MGLN | Buy | MAGELLAN HEALTH INC | $378,000 | +86.2% | 6,820 | +135.2% | 0.02% | +25.0% |
| CBM | Buy | CAMBREX CORP | $372,000 | +15.5% | 9,384 | +28.0% | 0.02% | -21.1% |
| GTS | Buy | TRIPLE-S MGMT CORPcl b | $378,000 | +39.0% | 21,210 | +100.0% | 0.02% | -6.2% |
| WCG | New | WELLCARE HEALTH PLANS INC | $378,000 | – | 4,378 | – | 0.02% | – |
| ICLR | Buy | ICON PLC | $374,000 | +66.2% | 5,262 | +57.2% | 0.02% | +7.1% |
| LPNT | New | LIFEPOINT HEALTH INC | $358,000 | – | 5,044 | – | 0.01% | – |
| New | AMGEN INC | $354,000 | – | 2,560 | – | 0.01% | – | |
| INFI | Sell | INFINITY PHARMACEUTICALS INC | $338,000 | -24.7% | 40,000 | -2.4% | 0.01% | -48.1% |
| SCMP | New | SUCAMPO PHARMACEUTICALS INCcl a | $314,000 | – | 15,810 | – | 0.01% | – |
| LCI | New | LANNET INC | $336,000 | – | 8,096 | – | 0.01% | – |
| REPH | New | RECRO PHARMA INC | $290,000 | – | 24,126 | – | 0.01% | – |
| DVCR | Buy | DIVERSICARE HEALTHCARE SVCS | $254,000 | +28.3% | 24,674 | +60.9% | 0.01% | -16.7% |
| AMAG | New | AMAG PHARMACEUTICALS INC | $230,000 | – | 5,808 | – | 0.01% | – |
| MYGN | Buy | MYRIAD GENETICS INC | $188,000 | +121.2% | 5,000 | +100.0% | 0.01% | +60.0% |
| ELGX | Sell | ENDOLOGIX INC | $142,000 | -97.1% | 11,510 | -96.4% | 0.01% | -98.0% |
| NSPH | Buy | NANOSPHERE INC | $116,000 | +0.9% | 70,758 | +100.0% | 0.01% | -28.6% |
| JNP | Sell | JUNIPER PHARMACEUTICALS INC | $40,000 | -90.3% | 3,472 | -92.3% | 0.00% | -92.0% |
| NUVA | New | NUVASIVE INC | $24,000 | – | 504 | – | 0.00% | – |
| CAPR | Buy | CAPRICOR THERAPEUTICS INC | $32,000 | +60.0% | 8,000 | +100.0% | 0.00% | 0.0% |
| VRX | New | VALEANT PHARMACEUTICALS INTERNATIONAL INcall | $36,000 | – | 200 | – | 0.00% | – |
| XBI | New | STREETTRACKS SPDR BIOTEC ETFcall | $12,000 | – | 200 | – | 0.00% | – |
| IDRA | New | IDERA PHARMACEUTICALS INC | $10,000 | – | 3,074 | – | 0.00% | – |
| CNAT | Sell | CONATUS PHARMACEUTICALS INC | $4,000 | -99.2% | 850 | -99.2% | 0.00% | -100.0% |
| PCRX | Exit | PACIRA PHARMACEUTICALS INC | $0 | – | -50 | – | 0.00% | – |
| ASND | Exit | ASCENDIS PHARMA A Ssponsored adr | $0 | – | -10,000 | – | -0.01% | – |
| NEOT | Exit | NEOTHETICS INC | $0 | – | -20,000 | – | -0.01% | – |
| UNH | Exit | UNITEDHEALTH GROUP INC | $0 | – | -1,685 | – | -0.01% | – |
| SURG | Exit | SYNERGETICS USA INC | $0 | – | -44,266 | – | -0.01% | – |
| ENTA | Exit | ENANTA PHARMACEUTICALS INC | $0 | – | -4,956 | – | -0.01% | – |
| LMAT | Exit | LEMAITRE VASCULAR INC | $0 | – | -19,838 | – | -0.01% | – |
| MCK | Exit | MCKESSON CORP | $0 | – | -1,015 | – | -0.01% | – |
| CYH | Exit | COMMUNITY HEALTH SYS INC NEW | $0 | – | -3,978 | – | -0.02% | – |
| PAHC | Exit | PHIBRO ANIMAL HEALTH CORP | $0 | – | -6,809 | – | -0.02% | – |
| UHS | Exit | UNIVERSAL HLTH SVCS INCcl b | $0 | – | -1,883 | – | -0.02% | – |
| MRGE | Exit | MERGE HEALTHCARE INC | $0 | – | -55,015 | – | -0.02% | – |
| XENT | Exit | INTERSECT ENT INC | $0 | – | -10,251 | – | -0.02% | – |
| SUPN | Exit | SUPERNUS PHARMACEUTICALS INC | $0 | – | -19,470 | – | -0.02% | – |
| PARNF | Exit | PARNELL PHARMACEUT HLDGS LTD | $0 | – | -68,800 | – | -0.02% | – |
| KERX | Exit | KERYX BIOPHARMACEUTICALS INC | $0 | – | -34,380 | – | -0.02% | – |
| OREX | Exit | OREXIGEN THERAPEUTICS INC | $0 | – | -70,600 | – | -0.02% | – |
| CNMD | Exit | CONMED CORP | $0 | – | -8,554 | – | -0.03% | – |
| THC | Exit | TENET HEALTHCARE CORP | $0 | – | -8,500 | – | -0.03% | – |
| Exit | ABIOMED INC | $0 | – | -10,000 | – | -0.04% | – | |
| DHR | Exit | DANAHER CORP DEL | $0 | – | -10,000 | – | -0.05% | – |
| IMPR | Exit | IMPRIVATA INC | $0 | – | -60,000 | – | -0.06% | – |
| GLPG | Exit | GALAPAGOS NVspon adr | $0 | – | -20,000 | – | -0.06% | – |
| TCON | Exit | TRACON PHARMACEUTICALS INC | $0 | – | -100,000 | – | -0.08% | – |
| EPZM | Exit | EPIZYME INC | $0 | – | -60,000 | – | -0.09% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -15,000 | – | -0.09% | – |
| SSO | Exit | PROSHARES TR | $0 | – | -30,000 | – | -0.12% | – |
| MCRB | Exit | SERES THERAPEUTICS INC | $0 | – | -50,000 | – | -0.12% | – |
| RGLS | Exit | REGULUS THERAPEUTICS INCput | $0 | – | -200,000 | – | -0.13% | – |
| CSBR | Exit | CHAMPIONS ONCOLOGY | $0 | – | -4,471,180 | – | -0.14% | – |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -600,000 | – | -0.15% | – |
| IMMU | Exit | IMMUNOMEDICS INCput | $0 | – | -700,000 | – | -0.17% | – |
| MDGN | Exit | MEDGENICS INC | $0 | – | -465,225 | – | -0.17% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -76,208 | – | -0.17% | – |
| RTRX | Exit | RETROPHIN INCput | $0 | – | -100,000 | – | -0.20% | – |
| RPTP | Exit | RAPTOR PHARMACEUTICAL CORP | $0 | – | -264,204 | – | -0.25% | – |
| NKTR | Exit | NEKTAR THERAPEUTICS | $0 | – | -335,000 | – | -0.25% | – |
| TTPH | Exit | TETRAPHASE PHARMACEUTICALS I | $0 | – | -100,000 | – | -0.29% | – |
| PTLA | Exit | PORTOLA PHARMACEUTICALS INC | $0 | – | -111,103 | – | -0.30% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -25,000 | – | -0.33% | – |
| VTL | Exit | VITAL THERAPIES INCput | $0 | – | -300,000 | – | -0.38% | – |
| INSM | Exit | INSMED INC | $0 | – | -285,812 | – | -0.42% | – |
| Exit | SUPERNUS PHARMACEUTICALS INCnote 7.500% 5/0 | $0 | – | -2,187,000 | – | -0.42% | – | |
| CHRS | Exit | COHERUS BIOSCIENCES INC | $0 | – | -258,716 | – | -0.45% | – |
| SGMO | Exit | SANGAMO BIOSCIENCES INC | $0 | – | -800,000 | – | -0.53% | – |
| RCPT | Exit | RECEPTOS INC | $0 | – | -60,969 | – | -0.70% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INCcall | $0 | – | -100,000 | – | -0.70% | – |
| HRTX | Exit | HERON THERAPEUTICS INC | $0 | – | -448,000 | – | -0.84% | – |
| MYL | Exit | MYLAN N V | $0 | – | -215,133 | – | -0.88% | – |
| ZBH | Exit | ZIMMER BIOMET HLDGS INC | $0 | – | -135,193 | – | -0.89% | – |
| RDUS | Exit | RADIUS HEALTH INC | $0 | – | -235,530 | – | -0.96% | – |
| ESPR | Exit | ESPERION THERAPEUTICS INCcall | $0 | – | -200,000 | – | -0.98% | – |
| CBPO | Exit | CHINA BIOLOGIC PRODS INC | $0 | – | -147,604 | – | -1.02% | – |
| AGN | Exit | ALLERGAN PLC | $0 | – | -59,185 | – | -1.08% | – |
| ZSPH | Exit | ZS PHARMA INC | $0 | – | -361,777 | – | -1.14% | – |
Q2 2015
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FOLD | New | AMICUS THERAPEUTICS INC | $204,318,000 | – | 14,439,444 | – | 12.30% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $156,866,000 | – | 3,284,467 | – | 9.45% | – |
| RTRX | New | RETROPHIN INC | $91,650,000 | – | 2,820,875 | – | 5.52% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $85,494,000 | – | 2,809,528 | – | 5.15% | – |
| TSRO | New | TESARO INC | $49,111,000 | – | 835,359 | – | 2.96% | – |
| DYAX | New | DYAX CORP | $47,337,000 | – | 1,786,315 | – | 2.85% | – |
| NVRO | New | NEVRO CORP | $42,944,000 | – | 798,959 | – | 2.59% | – |
| XNCR | New | XENCOR INC | $41,409,000 | – | 1,884,784 | – | 2.49% | – |
| XBI | New | STREETTRACKS SPDR BIOTEC ETFput | $37,836,000 | – | 150,000 | – | 2.28% | – |
| RLYP | New | RELYPSA INC | $37,694,000 | – | 1,139,142 | – | 2.27% | – |
| RXDX | New | IGNYTA INC | $29,691,000 | – | 1,967,600 | – | 1.79% | – |
| ACRX | New | ACELRX PHARMACEUTICALS INC | $27,874,000 | – | 6,574,060 | – | 1.68% | – |
| LBIO | New | LION BIOTECHNOLOGIES INC | $25,305,000 | – | 2,759,593 | – | 1.52% | – |
| DSCI | New | DERMA SCIENCES INC | $24,997,000 | – | 348,784 | – | 1.50% | – |
| GILD | New | GILEAD SCIENCES INCput | $23,416,000 | – | 200,000 | – | 1.41% | – |
| ANIP | New | ANI PHARMACEUTICALS INC | $20,300,000 | – | 327,157 | – | 1.22% | – |
| VSAR | New | VERSARTIS INC | $20,112,000 | – | 1,321,400 | – | 1.21% | – |
| CEMP | New | CEMPRA INC | $19,671,000 | – | 572,500 | – | 1.18% | – |
| PFNX | New | PFENEX INC | $19,611,000 | – | 1,010,877 | – | 1.18% | – |
| ZSPH | New | ZS PHARMA INC | $18,953,000 | – | 361,777 | – | 1.14% | – |
| EGRX | New | EAGLE PHARMACEUTICALS INC | $18,844,000 | – | 233,044 | – | 1.14% | – |
| AGN | New | ALLERGAN PLC | $17,960,000 | – | 59,185 | – | 1.08% | – |
| QURE | New | UNIQURE NV | $17,557,000 | – | 650,269 | – | 1.06% | – |
| New | ACADIA PHARMACEUTICALS INC | $17,181,000 | – | 410,240 | – | 1.04% | – | |
| CBPO | New | CHINA BIOLOGIC PRODS INC | $16,998,000 | – | 147,604 | – | 1.02% | – |
| ESPR | New | ESPERION THERAPEUTICS INCcall | $16,352,000 | – | 200,000 | – | 0.98% | – |
| RDUS | New | RADIUS HEALTH INC | $15,945,000 | – | 235,530 | – | 0.96% | – |
| CSU | New | CAPITAL SR LIVING CORP | $15,692,000 | – | 640,500 | – | 0.94% | – |
| SRPT | New | Sarepta Therapeutics Inccall | $15,215,000 | – | 500,000 | – | 0.92% | – |
| New | ASSEMBLY BIOSCIENCES INC | $15,117,000 | – | 784,893 | – | 0.91% | – | |
| ZBH | New | ZIMMER BIOMET HLDGS INC | $14,767,000 | – | 135,193 | – | 0.89% | – |
| MYL | New | MYLAN N V | $14,599,000 | – | 215,133 | – | 0.88% | – |
| HRTX | New | HERON THERAPEUTICS INC | $13,960,000 | – | 448,000 | – | 0.84% | – |
| AFMD | New | AFFIMED N V | $13,791,000 | – | 1,023,820 | – | 0.83% | – |
| ONTY | New | ONCOTHYREON INC | $12,517,000 | – | 3,346,897 | – | 0.75% | – |
| New | BELLICUM PHARMACEUTICALS | $11,754,000 | – | 552,628 | – | 0.71% | – | |
| PBYI | New | PUMA BIOTECHNOLOGY INCcall | $11,675,000 | – | 100,000 | – | 0.70% | – |
| RCPT | New | RECEPTOS INC | $11,587,000 | – | 60,969 | – | 0.70% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $10,712,000 | – | 404,404 | – | 0.64% | – |
| ANTH | New | ANTHERA PHARMACEUTICALS INC | $10,363,000 | – | 1,202,156 | – | 0.62% | – |
| New | ALLIQUA BIOMEDICAL INC | $10,128,000 | – | 1,921,951 | – | 0.61% | – | |
| THOR | New | THORATEC CORP | $10,073,000 | – | 226,000 | – | 0.61% | – |
| SHPG | New | SHIRE PLCsponsored adr | $9,660,000 | – | 40,000 | – | 0.58% | – |
| SGMO | New | SANGAMO BIOSCIENCES INC | $8,872,000 | – | 800,000 | – | 0.53% | – |
| XLRN | New | ACCELERON PHARMA INC | $8,734,000 | – | 276,036 | – | 0.53% | – |
| NEPT | New | NEPTUNE TECHNOLOGIES BIORESO | $8,643,000 | – | 6,700,444 | – | 0.52% | – |
| QTNT | New | QUOTIENT LTD | $8,577,000 | – | 562,436 | – | 0.52% | – |
| New | ANI PHARMACEUTICALS INCnote 3.000%12/0 | $8,488,000 | – | 7,500,000 | – | 0.51% | – | |
| OTIC | New | OTONOMY INC | $8,446,000 | – | 367,386 | – | 0.51% | – |
| CHRS | New | COHERUS BIOSCIENCES INC | $7,477,000 | – | 258,716 | – | 0.45% | – |
| BCRX | New | BIOCRYST PHARMACEUTICALS | $7,017,000 | – | 470,000 | – | 0.42% | – |
| New | SUPERNUS PHARMACEUTICALS INCnote 7.500% 5/0 | $7,008,000 | – | 2,187,000 | – | 0.42% | – | |
| INSM | New | INSMED INC | $6,980,000 | – | 285,812 | – | 0.42% | – |
| VBIV | New | VBI VACCINES INC | $6,813,000 | – | 2,610,365 | – | 0.41% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $6,749,000 | – | 869,800 | – | 0.41% | – |
| CLLS | New | CELLECTIS S Asponsored ads | $6,549,000 | – | 181,500 | – | 0.39% | – |
| TKAI | New | TOKAI PHARMACEUTICALS INC | $6,455,000 | – | 485,338 | – | 0.39% | – |
| VTL | New | VITAL THERAPIES INCput | $6,330,000 | – | 300,000 | – | 0.38% | – |
| LJPC | New | LA JOLLA PHARMACEUTICAL CO | $6,199,000 | – | 252,915 | – | 0.37% | – |
| TRXC | New | TRANSENTERIX INC | $6,132,000 | – | 2,044,032 | – | 0.37% | – |
| IRWD | New | IRONWOOD PHARMACEUTICALS INC | $5,953,000 | – | 493,600 | – | 0.36% | – |
| FPRX | New | FIVE PRIME THERAPEUTICS INC | $5,567,000 | – | 224,129 | – | 0.34% | – |
| ILMN | New | ILLUMINA INC | $5,459,000 | – | 25,000 | – | 0.33% | – |
| PTLA | New | PORTOLA PHARMACEUTICALS INC | $5,061,000 | – | 111,103 | – | 0.30% | – |
| New | ARDELYX INC | $5,046,000 | – | 315,955 | – | 0.30% | – | |
| PRTO | New | PROTEON THERAPEUTICS INC | $4,912,000 | – | 275,000 | – | 0.30% | – |
| ELGX | New | ENDOLOGIX INC | $4,878,000 | – | 318,000 | – | 0.29% | – |
| TTPH | New | TETRAPHASE PHARMACEUTICALS I | $4,744,000 | – | 100,000 | – | 0.29% | – |
| NERV | New | MINVERA NEUROSCIENCES | $4,701,000 | – | 810,537 | – | 0.28% | – |
| AGTC | New | APPLIED GENETIC TECHNOL CORP | $4,616,000 | – | 300,922 | – | 0.28% | – |
| HCA | New | HCA HOLDINGS INC | $4,587,000 | – | 50,563 | – | 0.28% | – |
| THOR | New | THORATEC CORPcall | $4,457,000 | – | 100,000 | – | 0.27% | – |
| CDTX | New | CIDARA THERAPEUTICS INC | $4,206,000 | – | 300,000 | – | 0.25% | – |
| NKTR | New | NEKTAR THERAPEUTICS | $4,191,000 | – | 335,000 | – | 0.25% | – |
| RPTP | New | RAPTOR PHARMACEUTICAL CORP | $4,172,000 | – | 264,204 | – | 0.25% | – |
| CYAD | New | CELYAD SAadr | $3,902,000 | – | 75,000 | – | 0.24% | – |
| AXGT | New | AXOVANT SCIENCES LTD | $3,872,000 | – | 190,000 | – | 0.23% | – |
| CI | New | CIGNA CORPORATION | $3,559,000 | – | 21,970 | – | 0.21% | – |
| CPRX | New | CATALYST PHARMACEUTICALS INC | $3,515,000 | – | 851,200 | – | 0.21% | – |
| RTRX | New | RETROPHIN INCput | $3,315,000 | – | 100,000 | – | 0.20% | – |
| SSO | New | PROSHARES ULTRA S & P500put | $3,227,000 | – | 50,000 | – | 0.19% | – |
| New | NEURODERM LTD | $3,070,000 | – | 200,000 | – | 0.18% | – | |
| WBA | New | WALGREENS BOOTS ALLIANCE INC | $2,980,000 | – | 35,292 | – | 0.18% | – |
| EVH | New | EVOLENT HEALTH INCcl a | $2,980,000 | – | 152,800 | – | 0.18% | – |
| MGNX | New | MACROGENICS INC | $2,894,000 | – | 76,208 | – | 0.17% | – |
| MDGN | New | MEDGENICS INC | $2,852,000 | – | 465,225 | – | 0.17% | – |
| IMMU | New | IMMUNOMEDICS INCput | $2,842,000 | – | 700,000 | – | 0.17% | – |
| CRBP | New | CORBUS PHARMACEUTICALS HOLDINGS INC | $2,679,000 | – | 870,000 | – | 0.16% | – |
| DERM | New | DERMIRA INC | $2,668,000 | – | 152,000 | – | 0.16% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $2,594,000 | – | 225,000 | – | 0.16% | – |
| IMMU | New | IMMUNOMEDICS INC | $2,436,000 | – | 600,000 | – | 0.15% | – |
| ABEO | New | ABEONA THERAPEUTICS INC | $2,378,000 | – | 470,000 | – | 0.14% | – |
| NVTA | New | INVITAE CORP | $2,306,000 | – | 299,583 | – | 0.14% | – |
| HEWG | New | ISHARES TRhdg msci germn | $2,270,000 | – | 87,000 | – | 0.14% | – |
| UUP | New | POWERSHS DB US DOLLAR INDEXdoll indx bull | $2,253,000 | – | 90,000 | – | 0.14% | – |
| ABEOW | New | ABEONA THERAPEUTICS INC*w exp 12/19/201 | $2,250,000 | – | 1,250,000 | – | 0.14% | – |
| CSBR | New | CHAMPIONS ONCOLOGY | $2,235,000 | – | 4,471,180 | – | 0.14% | – |
| RGLS | New | REGULUS THERAPEUTICS INCput | $2,196,000 | – | 200,000 | – | 0.13% | – |
| VTAE | New | VITAE PHARMACEUTICALS INC | $2,160,000 | – | 150,000 | – | 0.13% | – |
| SNSS | New | SUNESIS PHARMACEUTICALS INC | $2,107,000 | – | 700,000 | – | 0.13% | – |
| MCRB | New | SERES THERAPEUTICS INC | $2,075,000 | – | 50,000 | – | 0.12% | – |
| SSO | New | PROSHARES TR | $1,936,000 | – | 30,000 | – | 0.12% | – |
| VCEL | New | VERICEL CORP | $1,887,000 | – | 528,697 | – | 0.11% | – |
| MGCD | New | MGC DIAGNOSTICS CORP | $1,762,000 | – | 336,287 | – | 0.11% | – |
| ARIA | New | ARIAD PHARMACEUTICALS INC | $1,587,000 | – | 191,949 | – | 0.10% | – |
| INCY | New | INCYTE CORP | $1,563,000 | – | 15,000 | – | 0.09% | – |
| SCYX | New | SCYNEXIS INC | $1,538,000 | – | 175,000 | – | 0.09% | – |
| SAGE | New | SAGE THERAPEUTICS INC | $1,460,000 | – | 20,000 | – | 0.09% | – |
| BCLI | New | BRAINSTORM CELL THERAPEUTICS | $1,444,000 | – | 400,000 | – | 0.09% | – |
| EPZM | New | EPIZYME INC | $1,440,000 | – | 60,000 | – | 0.09% | – |
| New | AVINGER INC | $1,323,000 | – | 102,500 | – | 0.08% | – | |
| TCON | New | TRACON PHARMACEUTICALS INC | $1,294,000 | – | 100,000 | – | 0.08% | – |
| AET | New | AETNA INC NEW | $1,286,000 | – | 10,086 | – | 0.08% | – |
| GNVC | New | GENVEC INC | $1,256,000 | – | 615,844 | – | 0.08% | – |
| New | ARNO THERAPEUTICS INC | $1,221,000 | – | 2,034,721 | – | 0.07% | – | |
| PSDV | New | PSIVIDA CORP | $1,187,000 | – | 315,000 | – | 0.07% | – |
| CGNT | New | COGENTIX MED INC | $1,091,000 | – | 673,257 | – | 0.07% | – |
| GLPG | New | GALAPAGOS NVspon adr | $1,030,000 | – | 20,000 | – | 0.06% | – |
| IMPR | New | IMPRIVATA INC | $982,000 | – | 60,000 | – | 0.06% | – |
| STML | New | STEMLINE THERAPEUTICS INC | $933,000 | – | 79,245 | – | 0.06% | – |
| AQXP | New | AQUINOX PHARMACEUTICALS INC | $902,000 | – | 130,000 | – | 0.05% | – |
| FCAU | New | FIAT CHRYSLER AUTOMOBILES N | $901,000 | – | 62,000 | – | 0.05% | – |
| DHR | New | DANAHER CORP DEL | $856,000 | – | 10,000 | – | 0.05% | – |
| ACST | New | ACASTI PHARMA INC | $745,000 | – | 2,365,600 | – | 0.04% | – |
| GLMD | New | GALMED PHARMACEUTICALS LTD | $755,000 | – | 75,000 | – | 0.04% | – |
| DRNA | New | DICERNA PHARMACEUTICALS INC | $698,000 | – | 50,000 | – | 0.04% | – |
| New | ABIOMED INC | $657,000 | – | 10,000 | – | 0.04% | – | |
| New | TRILLIUM THERAPEUTICS INC | $655,000 | – | 30,000 | – | 0.04% | – | |
| CNAT | New | CONATUS PHARMACEUTICALS INC | $515,000 | – | 100,000 | – | 0.03% | – |
| CNMD | New | CONMED CORP | $498,000 | – | 8,554 | – | 0.03% | – |
| THC | New | TENET HEALTHCARE CORP | $492,000 | – | 8,500 | – | 0.03% | – |
| BVX | New | BOVIE MEDICAL CORP | $482,000 | – | 172,700 | – | 0.03% | – |
| INFI | New | INFINITY PHARMACEUTICALS INC | $449,000 | – | 41,000 | – | 0.03% | – |
| JNP | New | JUNIPER PHARMACEUTICALS INC | $411,000 | – | 44,900 | – | 0.02% | – |
| New | ACHAOGEN INC | $362,000 | – | 60,000 | – | 0.02% | – | |
| PARNF | New | PARNELL PHARMACEUT HLDGS LTD | $341,000 | – | 68,800 | – | 0.02% | – |
| KERX | New | KERYX BIOPHARMACEUTICALS INC | $343,000 | – | 34,380 | – | 0.02% | – |
| OREX | New | OREXIGEN THERAPEUTICS INC | $350,000 | – | 70,600 | – | 0.02% | – |
| SUPN | New | SUPERNUS PHARMACEUTICALS INC | $331,000 | – | 19,470 | – | 0.02% | – |
| CBM | New | CAMBREX CORP | $322,000 | – | 7,331 | – | 0.02% | – |
| XENT | New | INTERSECT ENT INC | $293,000 | – | 10,251 | – | 0.02% | – |
| INCR | New | INC RESH HLDGS INCcl a | $291,000 | – | 7,261 | – | 0.02% | – |
| GILD | New | GILEAD SCIENCES INC | $288,000 | – | 2,457 | – | 0.02% | – |
| UHS | New | UNIVERSAL HLTH SVCS INCcl b | $268,000 | – | 1,883 | – | 0.02% | – |
| PAHC | New | PHIBRO ANIMAL HEALTH CORP | $265,000 | – | 6,809 | – | 0.02% | – |
| MRGE | New | MERGE HEALTHCARE INC | $264,000 | – | 55,015 | – | 0.02% | – |
| GTS | New | TRIPLE-S MGMT CORPcl b | $272,000 | – | 10,605 | – | 0.02% | – |
| CYH | New | COMMUNITY HEALTH SYS INC NEW | $250,000 | – | 3,978 | – | 0.02% | – |
| HNT | New | HEALTH NET INC | $246,000 | – | 3,831 | – | 0.02% | – |
| PMC | New | PHARMERICA CORP | $226,000 | – | 6,800 | – | 0.01% | – |
| LMAT | New | LEMAITRE VASCULAR INC | $239,000 | – | 19,838 | – | 0.01% | – |
| LHCG | New | LHC GROUP INC | $226,000 | – | 5,917 | – | 0.01% | – |
| GB | New | GREATBATCH INC | $237,000 | – | 4,391 | – | 0.01% | – |
| ICLR | New | ICON PLC | $225,000 | – | 3,348 | – | 0.01% | – |
| MCK | New | MCKESSON CORP | $228,000 | – | 1,015 | – | 0.01% | – |
| New | ANTHEM INC | $236,000 | – | 1,436 | – | 0.01% | – | |
| CAH | New | CARDINAL HEALTH INC | $215,000 | – | 2,574 | – | 0.01% | – |
| SURG | New | SYNERGETICS USA INC | $208,000 | – | 44,266 | – | 0.01% | – |
| TARO | New | TARO PHARMACEUTICAL INDS LTD | $215,000 | – | 1,493 | – | 0.01% | – |
| ENTA | New | ENANTA PHARMACEUTICALS INC | $223,000 | – | 4,956 | – | 0.01% | – |
| UNH | New | UNITEDHEALTH GROUP INC | $206,000 | – | 1,685 | – | 0.01% | – |
| MOH | New | MOLINA HEALTHCARE INC | $203,000 | – | 2,888 | – | 0.01% | – |
| MGLN | New | MAGELLAN HEALTH INC | $203,000 | – | 2,900 | – | 0.01% | – |
| DVCR | New | DIVERSICARE HEALTHCARE SVCS | $198,000 | – | 15,337 | – | 0.01% | – |
| NEOT | New | NEOTHETICS INC | $180,000 | – | 20,000 | – | 0.01% | – |
| ASND | New | ASCENDIS PHARMA A Ssponsored adr | $176,000 | – | 10,000 | – | 0.01% | – |
| XIV | New | CREDIT SUISSE NASSAU BRHinvrs vix sterm | $162,000 | – | 4,000 | – | 0.01% | – |
| NVO | New | NOVO-NORDISK A Sadr | $128,000 | – | 2,340 | – | 0.01% | – |
| NSPH | New | NANOSPHERE INC | $115,000 | – | 35,379 | – | 0.01% | – |
| MYGN | New | MYRIAD GENETICS INC | $85,000 | – | 2,500 | – | 0.01% | – |
| DBVT | New | DBV TECHNOLOGIES S Asponsored adr | $89,000 | – | 3,002 | – | 0.01% | – |
| CAPR | New | CAPRICOR THERAPEUTICS INC | $20,000 | – | 4,000 | – | 0.00% | – |
| PCRX | New | PACIRA PHARMACEUTICALS INC | $4,000 | – | 50 | – | 0.00% | – |
Q4 2014
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ICEL | Exit | CELLULAR DYNAMICS INTL INC | $0 | – | -164 | – | 0.00% | – |
| AIQ | Exit | ALLIANCE HEALTHCARE SRVCS IN | $0 | – | -3,500 | – | -0.01% | – |
| PDLI | Exit | PDL BIOPHARMA INC | $0 | – | -10,183 | – | -0.01% | – |
| MRGE | Exit | MERGE HEALTHCARE INC | $0 | – | -43,478 | – | -0.01% | – |
| GB | Exit | GREATBATCH INC | $0 | – | -2,444 | – | -0.01% | – |
| LGND | Exit | LIGAND PHARMACEUTICALS INC | $0 | – | -2,245 | – | -0.01% | – |
| AET | Exit | AETNA INC NEW | $0 | – | -1,308 | – | -0.01% | – |
| MCK | Exit | MCKESSON CORP | $0 | – | -527 | – | -0.01% | – |
| EXAC | Exit | EXACTECH INC | $0 | – | -4,464 | – | -0.01% | – |
| HRC | Exit | HILL ROM HLDGS INC | $0 | – | -2,657 | – | -0.01% | – |
| CRL | Exit | CHARLES RIV LABS INTL INC | $0 | – | -1,860 | – | -0.01% | – |
| CNC | Exit | CENTENE CORP DEL | $0 | – | -1,336 | – | -0.01% | – |
| SEM | Exit | SELECT MED HLDGS CORP | $0 | – | -9,016 | – | -0.01% | – |
| SMA | Exit | SYMMETRY MED INC | $0 | – | -11,148 | – | -0.01% | – |
| SCLN | Exit | SCICLONE PHARMACEUTICALS INC | $0 | – | -16,035 | – | -0.01% | – |
| UHS | Exit | UNIVERSAL HLTH SVCS INCcl b | $0 | – | -1,101 | – | -0.01% | – |
| CYH | Exit | COMMUNITY HEALTH SYS INC NEW | $0 | – | -2,123 | – | -0.01% | – |
| V107SC | Exit | WELLPOINT INC | $0 | – | -901 | – | -0.01% | – |
| MGLN | Exit | MAGELLAN HEALTH INC | $0 | – | -2,189 | – | -0.01% | – |
| ENTA | Exit | ENANTA PHARMACEUTICALS INC | $0 | – | -3,040 | – | -0.01% | – |
| GTIV | Exit | GENTIVA HEALTH SERVICES INC | $0 | – | -7,052 | – | -0.01% | – |
| AMN | Exit | AMN HEALTHCARE SERVICES INC | $0 | – | -7,855 | – | -0.01% | – |
| GTS | Exit | TRIPLE-S MGMT CORPcl b | $0 | – | -5,880 | – | -0.01% | – |
| PRSC | Exit | PROVIDENCE SVC CORP | $0 | – | -2,532 | – | -0.01% | – |
| AMSG | Exit | AMSURG CORP | $0 | – | -2,348 | – | -0.01% | – |
| CBPO | Exit | CHINA BIOLOGIC PRODS INC | $0 | – | -2,400 | – | -0.01% | – |
| ICLR | Exit | ICON PLC | $0 | – | -2,440 | – | -0.02% | – |
| PTX | Exit | PERNIX THERAPEUTICS INCcall | $0 | – | -25,000 | – | -0.02% | – |
| NXTM | Exit | NXSTAGE MEDICAL INC | $0 | – | -20,000 | – | -0.03% | – |
| OXGN | Exit | OXIGENE INC | $0 | – | -123,518 | – | -0.03% | – |
| MDGN | Exit | MEDGENICS INC | $0 | – | -55,073 | – | -0.03% | – |
| AKAOQ | Exit | ACHAOGEN INC | $0 | – | -60,000 | – | -0.06% | – |
| THLD | Exit | THRESHOLD PHARMACEUTICAL INC | $0 | – | -160,000 | – | -0.06% | – |
| BOTA | Exit | BIOTA PHARMACEUTIALS INC | $0 | – | -253,400 | – | -0.07% | – |
| ABMD | Exit | ABIOMED INC | $0 | – | -25,000 | – | -0.07% | – |
| ONTY | Exit | ONCOTHYREON INC | $0 | – | -325,000 | – | -0.07% | – |
| GLMD | Exit | GALMED PHARMACEUTICALS LTD | $0 | – | -75,000 | – | -0.07% | – |
| TBIO | Exit | TRANSGENOMIC INC | $0 | – | -183,957 | – | -0.07% | – |
| AQXP | Exit | AQUINOX PHARMACEUTICALS INC | $0 | – | -130,000 | – | -0.09% | – |
| ANTH | Exit | ANTHERA PHARMACEUTICALS INC | $0 | – | -478,456 | – | -0.10% | – |
| SNN | Exit | SMITH & NEPHEW PLCspdn adr new | $0 | – | -12,963 | – | -0.12% | – |
| MNKD | Exit | MANNKIND CORPput | $0 | – | -200,000 | – | -0.13% | – |
| CSBR | Exit | CHAMPIONS ONCOLOGY | $0 | – | -1,625,744 | – | -0.13% | – |
| PARNF | Exit | PARNELL PHARMACEUT HLDGS LTD | $0 | – | -210,000 | – | -0.13% | – |
| DRRX | Exit | DURECT CORP | $0 | – | -907,064 | – | -0.14% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -30,917 | – | -0.15% | – |
| ELOS | Exit | SYNERON MEDICAL LTD | $0 | – | -150,000 | – | -0.16% | – |
| HIIQ | Exit | HEALTH INS INNOVATIONS INC | $0 | – | -131,025 | – | -0.17% | – |
| ACHN | Exit | ACHILLION PHARMACEUTICALS IN | $0 | – | -170,000 | – | -0.18% | – |
| GNVC | Exit | GENVEC INC | $0 | – | -820,000 | – | -0.18% | – |
| PRQR | Exit | PROQR THRAPEUTICS N V | $0 | – | -100,000 | – | -0.18% | – |
| UPI | Exit | UROPLASTY INC | $0 | – | -697,287 | – | -0.19% | – |
| FPRX | Exit | FIVE PRIME THERAPEUTICS INC | $0 | – | -150,000 | – | -0.19% | – |
| DSCI | Exit | DERMA SCIENCES INC | $0 | – | -215,809 | – | -0.19% | – |
| ACST | Exit | ACASTI PHARMA INC | $0 | – | -2,573,645 | – | -0.21% | – |
| ARDX | Exit | ARDELYX INC | $0 | – | -153,077 | – | -0.23% | – |
| MGCD | Exit | MGC DIAGNOSTICS CORP | $0 | – | -327,488 | – | -0.24% | – |
| MYL | Exit | MYLAN INC | $0 | – | -50,000 | – | -0.24% | – |
| LJPC | Exit | LA JOLLA PHARMACEUTICAL CO | $0 | – | -250,000 | – | -0.26% | – |
| Exit | CATALYST PHARM PARTNERS INC | $0 | – | -750,000 | – | -0.27% | – | |
| QTNT | Exit | QUOTIENT LTD | $0 | – | -263,844 | – | -0.27% | – |
| ASPX | Exit | AUSPEX PHARMACEUTICALS INC | $0 | – | -100,000 | – | -0.28% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INC | $0 | – | -11,000 | – | -0.28% | – |
| TKAI | Exit | TOKAI PHARMACEUTICALS INC | $0 | – | -180,000 | – | -0.29% | – |
| KERX | Exit | KERYX BIOPHARMACEUTICALSput | $0 | – | -200,000 | – | -0.30% | – |
| ARNI | Exit | ARNO THERAPEUTICS | $0 | – | -2,034,721 | – | -0.30% | – |
| SNSS | Exit | SUNESIS PHARMACEUTICALS INCcall | $0 | – | -400,000 | – | -0.31% | – |
| SNSS | Exit | SUNESIS PHARMACEUTICALS INCput | $0 | – | -400,000 | – | -0.31% | – |
| PFNX | Exit | PFENEX INC | $0 | – | -400,000 | – | -0.32% | – |
| WAG | Exit | WALGREEN CO | $0 | – | -50,000 | – | -0.32% | – |
| ASTM | Exit | AASTROM BIOSCIENCES INC | $0 | – | -1,100,000 | – | -0.34% | – |
| CMRX | Exit | CHIMERIX INC | $0 | – | -128,000 | – | -0.38% | – |
| B108PS | Exit | ACTAVIS PLC | $0 | – | -15,000 | – | -0.39% | – |
| SPNC | Exit | SPECTRANETICS CORP | $0 | – | -138,371 | – | -0.40% | – |
| THOR | Exit | THORATEC CORP | $0 | – | -147,501 | – | -0.42% | – |
| THC | Exit | TENET HEALTHCARE CORP | $0 | – | -67,500 | – | -0.43% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -213,703 | – | -0.48% | – |
| PCYC | Exit | PHARMACYCLICS INC | $0 | – | -40,000 | – | -0.50% | – |
| TRVN | Exit | TREVENA INC | $0 | – | -770,000 | – | -0.53% | – |
| BDSI | Exit | BIODELIVERY SCIENCES INTL IN | $0 | – | -306,000 | – | -0.56% | – |
| ZFGN | Exit | ZAFGEN INC | $0 | – | -275,000 | – | -0.58% | – |
| AERI | Exit | ALLIQUA INC | $0 | – | -1,121,951 | – | -0.58% | – |
| AVNR | Exit | AVANIR PHARMACEUTICALS INCcl a new | $0 | – | -460,000 | – | -0.59% | – |
| AGTC | Exit | APPLIED GENETIC TECHNOL CORP | $0 | – | -296,978 | – | -0.59% | – |
| TRXC | Exit | TRANSENTERIX INC | $0 | – | -1,311,941 | – | -0.61% | – |
| LCI | Exit | LANNET INC | $0 | – | -134,569 | – | -0.66% | – |
| AFMD | Exit | AFFIMED THERAPEUTICS B V | $0 | – | -99,989 | – | -0.68% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -208,676 | – | -0.71% | – |
| PRTA | Exit | PROTHENA CORP PLC | $0 | – | -300,000 | – | -0.71% | – |
| VNDA | Exit | VANDA PHARMACEUTICALS INCput | $0 | – | -700,000 | – | -0.78% | – |
| HRTX | Exit | HERON THERAPEUTICS INC | $0 | – | -885,352 | – | -0.79% | – |
| ADHD | Exit | ALCOBRA LTDput | $0 | – | -487,000 | – | -0.81% | – |
| EPZM | Exit | EPIZYME INC | $0 | – | -283,890 | – | -0.83% | – |
| INSM | Exit | INSMED INC | $0 | – | -600,000 | – | -0.84% | – |
| ADHD | Exit | ALCOBRA LTDcall | $0 | – | -537,000 | – | -0.89% | – |
| SGMO | Exit | SANGAMO BIOSCIENCES INC | $0 | – | -800,000 | – | -0.93% | – |
| FLML | Exit | FLAMEL TECHNOLOGIES SAsponsored adr | $0 | – | -610,000 | – | -0.94% | – |
| AGN | Exit | ALLERGAN INC | $0 | – | -50,000 | – | -0.96% | – |
| NEPT | Exit | NEPTUNE TECHNOLOGIES BIORESO | $0 | – | -6,700,444 | – | -0.97% | – |
| VSAR | Exit | VERSARTIS INC | $0 | – | -487,262 | – | -0.99% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INCput | $0 | – | -653,000 | – | -1.10% | – |
| AEGR | Exit | AEGERION PHARMACEUTICALS INC | $0 | – | -366,754 | – | -1.32% | – |
| RTRX | Exit | RETROPHIN INC | $0 | – | -1,379,137 | – | -1.34% | – |
| XLRN | Exit | ACCELERON PHARMA INC | $0 | – | -445,000 | – | -1.44% | – |
| RLYP | Exit | RELYPSA INC | $0 | – | -762,705 | – | -1.73% | – |
| HCA | Exit | HCA HOLDINGS INC | $0 | – | -230,306 | – | -1.74% | – |
| XNCR | Exit | XENCOR INC | $0 | – | -1,922,707 | – | -1.92% | – |
| ARWR | Exit | ARROWHEAD RESH CORP | $0 | – | -1,247,495 | – | -1.98% | – |
| TSRO | Exit | TESARO INC | $0 | – | -708,284 | – | -2.05% | – |
| RCPT | Exit | RECEPTOS INC | $0 | – | -313,594 | – | -2.09% | – |
| OTIC | Exit | OTONOMY INC | $0 | – | -837,400 | – | -2.16% | – |
| OPHT | Exit | OPHTHOTECH CORP | $0 | – | -520,165 | – | -2.17% | – |
| LBIO | Exit | LION BIOTECHNOLOGIES | $0 | – | -2,914,549 | – | -2.24% | – |
| TARO | Exit | TARO PHARMACEUTICAL INDS LTD | $0 | – | -140,935 | – | -2.33% | – |
| ZBH | Exit | ZIMMER HLDGS INC | $0 | – | -252,500 | – | -2.73% | – |
| SRPT | Exit | Sarepta Therapeutics Inccall | $0 | – | -1,250,000 | – | -2.83% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -240,142 | – | -2.90% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -1,097,914 | – | -2.92% | – |
| DYAX | Exit | DYAX CORP | $0 | – | -2,835,498 | – | -3.08% | – |
| PTCT | Exit | PTC THERAPEUTICS INC | $0 | – | -671,736 | – | -3.17% | – |
| CELG | Exit | CELGENE CORP | $0 | – | -377,448 | – | -3.84% | – |
| ACRX | Exit | ACELRX PHARMACEUTICALS INC | $0 | – | -6,574,060 | – | -3.88% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -2,596,691 | – | -5.88% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -4,565,267 | – | -7.68% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -12,339,444 | – | -7.88% | – |
Q3 2014
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NBIX | Sell | NEUROCRINE BIOSCIENCES INC | $71,538,000 | +4.8% | 4,565,267 | -0.8% | 7.68% | +14.7% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $54,790,000 | -28.1% | 2,596,691 | +1.5% | 5.88% | -21.3% |
| CELG | Sell | CELGENE CORP | $35,775,000 | -17.9% | 377,448 | -25.6% | 3.84% | -10.2% |
| DYAX | Buy | DYAX CORP | $28,695,000 | +10.3% | 2,835,498 | +4.6% | 3.08% | +20.7% |
| ACAD | Buy | ACADIA PHARMACEUTICALS INC | $27,184,000 | +84.3% | 1,097,914 | +68.1% | 2.92% | +101.7% |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $26,970,000 | -39.4% | 240,142 | -48.9% | 2.90% | -33.7% |
| SRPT | New | Sarepta Therapeutics Inccall | $26,375,000 | – | 1,250,000 | – | 2.83% | – |
| ZBH | Buy | ZIMMER HLDGS INC | $25,389,000 | +0.8% | 252,500 | +4.1% | 2.73% | +10.3% |
| TARO | Sell | TARO PHARMACEUTICAL INDS LTD | $21,684,000 | -48.7% | 140,935 | -53.2% | 2.33% | -43.8% |
| LBIO | Sell | LION BIOTECHNOLOGIES | $20,839,000 | +8.1% | 2,914,549 | -3.2% | 2.24% | +18.4% |
| OPHT | Buy | OPHTHOTECH CORP | $20,250,000 | +28.8% | 520,165 | +40.0% | 2.17% | +41.0% |
| OTIC | New | OTONOMY INC | $20,098,000 | – | 837,400 | – | 2.16% | – |
| RCPT | Buy | RECEPTOS INC | $19,477,000 | +123.0% | 313,594 | +53.0% | 2.09% | +144.0% |
| TSRO | Buy | TESARO INC | $19,067,000 | -3.8% | 708,284 | +11.2% | 2.05% | +5.3% |
| ARWR | Buy | ARROWHEAD RESH CORP | $18,426,000 | +204.8% | 1,247,495 | +195.3% | 1.98% | +233.7% |
| XNCR | Buy | XENCOR INC | $17,900,000 | -11.5% | 1,922,707 | +10.5% | 1.92% | -3.1% |
| HCA | Buy | HCA HOLDINGS INC | $16,241,000 | +45.6% | 230,306 | +16.4% | 1.74% | +59.4% |
| RLYP | Buy | RELYPSA INC | $16,085,000 | +10.9% | 762,705 | +27.8% | 1.73% | +21.4% |
| XLRN | Buy | ACCELERON PHARMA INC | $13,457,000 | +32.0% | 445,000 | +48.3% | 1.44% | +44.5% |
| RTRX | Buy | RETROPHIN INC | $12,438,000 | -16.9% | 1,379,137 | +8.2% | 1.34% | -9.0% |
| AEGR | New | AEGERION PHARMACEUTICALS INC | $12,242,000 | – | 366,754 | – | 1.32% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INCput | $10,233,000 | – | 653,000 | – | 1.10% | – |
| VSAR | Buy | VERSARTIS INC | $9,253,000 | +4.5% | 487,262 | +54.3% | 0.99% | +14.4% |
| FLML | Sell | FLAMEL TECHNOLOGIES SAsponsored adr | $8,729,000 | -27.3% | 610,000 | -23.8% | 0.94% | -20.4% |
| ADHD | New | ALCOBRA LTDcall | $8,291,000 | – | 537,000 | – | 0.89% | – |
| INSM | Sell | INSMED INC | $7,830,000 | -78.2% | 600,000 | -66.7% | 0.84% | -76.2% |
| EPZM | Buy | EPIZYME INC | $7,696,000 | +480.4% | 283,890 | +566.4% | 0.83% | +535.4% |
| ADHD | New | ALCOBRA LTDput | $7,519,000 | – | 487,000 | – | 0.81% | – |
| HRTX | Sell | HERON THERAPEUTICS INC | $7,375,000 | -63.4% | 885,352 | -45.8% | 0.79% | -59.9% |
| VNDA | New | VANDA PHARMACEUTICALS INCput | $7,266,000 | – | 700,000 | – | 0.78% | – |
| PRTA | Sell | PROTHENA CORP PLC | $6,648,000 | -39.0% | 300,000 | -37.9% | 0.71% | -33.2% |
| SAGE | New | SAGE THERAPEUTICS INC | $6,573,000 | – | 208,676 | – | 0.71% | – |
| AFMD | New | AFFIMED THERAPEUTICS B V | $6,300,000 | – | 99,989 | – | 0.68% | – |
| LCI | New | LANNET INC | $6,147,000 | – | 134,569 | – | 0.66% | – |
| TRXC | Buy | TRANSENTERIX INC | $5,720,000 | -12.7% | 1,311,941 | +0.9% | 0.61% | -4.5% |
| AGTC | Buy | APPLIED GENETIC TECHNOL CORP | $5,527,000 | +62.8% | 296,978 | +102.1% | 0.59% | +78.1% |
| AVNR | New | AVANIR PHARMACEUTICALS INCcl a new | $5,483,000 | – | 460,000 | – | 0.59% | – |
| ZFGN | New | ZAFGEN INC | $5,404,000 | – | 275,000 | – | 0.58% | – |
| BDSI | Sell | BIODELIVERY SCIENCES INTL IN | $5,230,000 | -38.1% | 306,000 | -56.3% | 0.56% | -32.2% |
| PCYC | New | PHARMACYCLICS INC | $4,697,000 | – | 40,000 | – | 0.50% | – |
| MGNX | Sell | MACROGENICS INC | $4,466,000 | -52.4% | 213,703 | -50.5% | 0.48% | -47.9% |
| THC | New | TENET HEALTHCARE CORP | $4,009,000 | – | 67,500 | – | 0.43% | – |
| THOR | New | THORATEC CORP | $3,943,000 | – | 147,501 | – | 0.42% | – |
| SPNC | Sell | SPECTRANETICS CORP | $3,677,000 | -34.0% | 138,371 | -43.1% | 0.40% | -27.7% |
| B108PS | New | ACTAVIS PLC | $3,619,000 | – | 15,000 | – | 0.39% | – |
| CMRX | Sell | CHIMERIX INC | $3,535,000 | +9.1% | 128,000 | -13.5% | 0.38% | +19.5% |
| ASTM | New | AASTROM BIOSCIENCES INC | $3,135,000 | – | 1,100,000 | – | 0.34% | – |
| WAG | Sell | WALGREEN CO | $2,964,000 | -85.8% | 50,000 | -82.3% | 0.32% | -84.5% |
| PFNX | New | PFENEX INC | $2,944,000 | – | 400,000 | – | 0.32% | – |
| SNSS | New | SUNESIS PHARMACEUTICALS INCcall | $2,856,000 | – | 400,000 | – | 0.31% | – |
| SNSS | New | SUNESIS PHARMACEUTICALS INCput | $2,856,000 | – | 400,000 | – | 0.31% | – |
| KERX | New | KERYX BIOPHARMACEUTICALSput | $2,750,000 | – | 200,000 | – | 0.30% | – |
| ARNI | New | ARNO THERAPEUTICS | $2,746,000 | – | 2,034,721 | – | 0.30% | – |
| TKAI | New | TOKAI PHARMACEUTICALS INC | $2,725,000 | – | 180,000 | – | 0.29% | – |
| PBYI | New | PUMA BIOTECHNOLOGY INC | $2,624,000 | – | 11,000 | – | 0.28% | – |
| ASPX | New | AUSPEX PHARMACEUTICALS INC | $2,567,000 | – | 100,000 | – | 0.28% | – |
| QTNT | Sell | QUOTIENT LTD | $2,493,000 | -0.2% | 263,844 | -12.1% | 0.27% | +9.4% |
| New | CATALYST PHARM PARTNERS INC | $2,490,000 | – | 750,000 | – | 0.27% | – | |
| LJPC | New | LA JOLLA PHARMACEUTICAL CO | $2,403,000 | – | 250,000 | – | 0.26% | – |
| MYL | Sell | MYLAN INC | $2,275,000 | -84.4% | 50,000 | -82.3% | 0.24% | -82.9% |
| MGCD | Buy | MGC DIAGNOSTICS CORP | $2,227,000 | -16.0% | 327,488 | +3.5% | 0.24% | -8.1% |
| ARDX | New | ARDELYX INC | $2,175,000 | – | 153,077 | – | 0.23% | – |
| ACST | Buy | ACASTI PHARMA INC | $1,982,000 | -18.7% | 2,573,645 | +0.3% | 0.21% | -10.9% |
| DSCI | Sell | DERMA SCIENCES INC | $1,798,000 | -61.7% | 215,809 | -46.9% | 0.19% | -58.1% |
| UPI | Buy | UROPLASTY INC | $1,743,000 | -2.7% | 697,287 | +4.3% | 0.19% | +6.2% |
| PRQR | New | PROQR THRAPEUTICS N V | $1,719,000 | – | 100,000 | – | 0.18% | – |
| ACHN | Sell | ACHILLION PHARMACEUTICALS IN | $1,697,000 | -20.0% | 170,000 | -39.3% | 0.18% | -12.5% |
| HIIQ | New | HEALTH INS INNOVATIONS INC | $1,591,000 | – | 131,025 | – | 0.17% | – |
| ELOS | Buy | SYNERON MEDICAL LTD | $1,503,000 | +26.6% | 150,000 | +30.4% | 0.16% | +38.8% |
| CLVS | Buy | CLOVIS ONCOLOGY INC | $1,402,000 | +210.2% | 30,917 | +183.2% | 0.15% | +243.2% |
| PARNF | New | PARNELL PHARMACEUT HLDGS LTD | $1,208,000 | – | 210,000 | – | 0.13% | – |
| MNKD | New | MANNKIND CORPput | $1,182,000 | – | 200,000 | – | 0.13% | – |
| SNN | Sell | SMITH & NEPHEW PLCspdn adr new | $1,091,000 | -46.8% | 12,963 | -43.5% | 0.12% | -41.8% |
| ANTH | New | ANTHERA PHARMACEUTICALS INC | $919,000 | – | 478,456 | – | 0.10% | – |
| ABMD | New | ABIOMED INC | $621,000 | – | 25,000 | – | 0.07% | – |
| ONTY | Buy | ONCOTHYREON INC | $624,000 | -34.2% | 325,000 | +11.0% | 0.07% | -28.0% |
| THLD | New | THRESHOLD PHARMACEUTICAL INC | $578,000 | – | 160,000 | – | 0.06% | – |
| OXGN | Sell | OXIGENE INC | $266,000 | -72.9% | 123,518 | -67.4% | 0.03% | -69.8% |
| NXTM | New | NXSTAGE MEDICAL INC | $263,000 | – | 20,000 | – | 0.03% | – |
| PTX | New | PERNIX THERAPEUTICS INCcall | $192,000 | – | 25,000 | – | 0.02% | – |
| AMN | New | AMN HEALTHCARE SERVICES INC | $123,000 | – | 7,855 | – | 0.01% | – |
| AMSG | Buy | AMSURG CORP | $118,000 | +31.1% | 2,348 | +18.6% | 0.01% | +44.4% |
| ENTA | New | ENANTA PHARMACEUTICALS INC | $120,000 | – | 3,040 | – | 0.01% | – |
| MGLN | Buy | MAGELLAN HEALTH INC | $120,000 | +17.6% | 2,189 | +33.3% | 0.01% | +30.0% |
| PRSC | New | PROVIDENCE SVC CORP | $122,000 | – | 2,532 | – | 0.01% | – |
| SCLN | New | SCICLONE PHARMACEUTICALS INC | $110,000 | – | 16,035 | – | 0.01% | – |
| CYH | New | COMMUNITY HEALTH SYS INC NEW | $116,000 | – | 2,123 | – | 0.01% | – |
| CNC | Sell | CENTENE CORP DEL | $111,000 | -97.6% | 1,336 | -97.8% | 0.01% | -97.3% |
| V107SC | New | WELLPOINT INC | $108,000 | – | 901 | – | 0.01% | – |
| UHS | Sell | UNIVERSAL HLTH SVCS INCcl b | $115,000 | -46.3% | 1,101 | -50.8% | 0.01% | -42.9% |
| SEM | New | SELECT MED HLDGS CORP | $108,000 | – | 9,016 | – | 0.01% | – |
| HRC | New | HILL ROM HLDGS INC | $110,000 | – | 2,657 | – | 0.01% | – |
| AET | Sell | AETNA INC NEW | $106,000 | -99.0% | 1,308 | -99.0% | 0.01% | -98.9% |
| MCK | Sell | MCKESSON CORP | $103,000 | +4.0% | 527 | -0.6% | 0.01% | +10.0% |
| LGND | Sell | LIGAND PHARMACEUTICALS INC | $105,000 | -93.9% | 2,245 | -91.9% | 0.01% | -93.5% |
| GB | New | GREATBATCH INC | $104,000 | – | 2,444 | – | 0.01% | – |
| AIQ | New | ALLIANCE HEALTHCARE SRVCS IN | $79,000 | – | 3,500 | – | 0.01% | – |
| ICEL | New | CELLULAR DYNAMICS INTL INC | $1,000 | – | 164 | – | 0.00% | – |
| BSTC | Exit | BIOSPECIFICS TECHNOLOGIES CO | $0 | – | -3,700 | – | -0.01% | – |
| PMC | Exit | PHARMERICA CORP | $0 | – | -3,441 | – | -0.01% | – |
| AFAM | Exit | ALMOST FAMILY INC | $0 | – | -4,708 | – | -0.01% | – |
| Q | Exit | QUINTILES TRANSNATIO HLDGS I | $0 | – | -1,875 | – | -0.01% | – |
| MDAS | Exit | MEDASSETS INC | $0 | – | -4,429 | – | -0.01% | – |
| BCR | Exit | BARD C R INC | $0 | – | -676 | – | -0.01% | – |
| MOH | Exit | MOLINA HEALTHCARE INC | $0 | – | -2,380 | – | -0.01% | – |
| WCG | Exit | WELLCARE HEALTH PLANS INC | $0 | – | -1,302 | – | -0.01% | – |
| HUM | Exit | HUMANA INC | $0 | – | -803 | – | -0.01% | – |
| ENSG | Exit | ENSIGN GROUP INC | $0 | – | -3,509 | – | -0.01% | – |
| SSH | Exit | SUNSHINE HEART INC | $0 | – | -25,000 | – | -0.01% | – |
| RDNT | Exit | RADNET INC | $0 | – | -22,975 | – | -0.02% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INCput | $0 | – | -30,000 | – | -0.02% | – |
| HNT | Exit | HEALTH NET INC | $0 | – | -6,025 | – | -0.02% | – |
| BLRX | Exit | BIOLINERX LTDsponsored adr | $0 | – | -165,698 | – | -0.03% | – |
| STEM | Exit | STEMCELLS INC | $0 | – | -271,600 | – | -0.05% | – |
| ICAD | Exit | ICAD INC | $0 | – | -150,000 | – | -0.09% | – |
| ATHX | Exit | ATHERSYS INC | $0 | – | -601,852 | – | -0.11% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -20,000 | – | -0.11% | – |
| NLNK | Exit | NEWLINK GENETICS CORPcall | $0 | – | -50,000 | – | -0.13% | – |
| EXEL | Exit | EXELIXIS INCcall | $0 | – | -400,000 | – | -0.13% | – |
| OREX | Exit | OREXIGEN THERAPEUTICS INC | $0 | – | -224,000 | – | -0.14% | – |
| Exit | ANTHERA PHARMACEUTICALS INC | $0 | – | -478,456 | – | -0.16% | – | |
| KPTI | Exit | KARYOPHARM THERAPEUTICS INC | $0 | – | -45,643 | – | -0.21% | – |
| F113PS | Exit | COVIDIEN PLC | $0 | – | -25,000 | – | -0.22% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INCput | $0 | – | -30,000 | – | -0.28% | – |
| ZLTQ | Exit | ZELTIQ AESTHETICS INC | $0 | – | -201,628 | – | -0.30% | – |
| TSRO | Exit | TESARO INCput | $0 | – | -100,000 | – | -0.30% | – |
| AEGR | Exit | AEGERION PHARMACEUTICALS ORDcall | $0 | – | -100,000 | – | -0.32% | – |
| Exit | ARNO THERAPEUTICS | $0 | – | -2,034,721 | – | -0.36% | – | |
| WAG | Exit | WALGREEN COcall | $0 | – | -50,000 | – | -0.36% | – |
| CPRX | Exit | CATALYST PHARM PARTNERS INC | $0 | – | -1,500,000 | – | -0.37% | – |
| ICPT | Exit | INTERCEPT INCput | $0 | – | -20,000 | – | -0.46% | – |
| RGDO | Exit | REGADO BIOSCIENCES INC | $0 | – | -860,000 | – | -0.57% | – |
| MDT | Exit | MEDTRONIC INC | $0 | – | -130,000 | – | -0.81% | – |
| ITMN | Exit | INTERMUNE INC | $0 | – | -210,000 | – | -0.91% | – |
| ANAC | Exit | ANACOR PHARMACEUTICALS INC | $0 | – | -528,776 | – | -0.92% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -901,250 | – | -1.51% | – |
| SHPG | Exit | SHIRE PLCsponsored adr | $0 | – | -90,000 | – | -2.08% | – |
| QCOR | Exit | QUESTCOR PHARMACEUTICALS INC | $0 | – | -400,000 | – | -3.63% | – |
Q2 2014
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SRPT | New | SAREPTA THERAPEUTICS INC | $76,217,000 | – | 2,558,478 | – | 7.48% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $68,262,000 | – | 4,599,867 | – | 6.70% | – |
| ACRX | New | ACELRX PHARMACEUTICALS INC | $67,384,000 | – | 6,574,060 | – | 6.61% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $44,513,000 | – | 470,142 | – | 4.37% | – |
| CELG | New | CELGENE CORP | $43,580,000 | – | 507,488 | – | 4.28% | – |
| TARO | New | TARO PHARMACEUTICAL INDS LTD | $42,260,000 | – | 301,333 | – | 4.15% | – |
| FOLD | New | AMICUS THERAPEUTICS INC | $41,214,000 | – | 12,339,444 | – | 4.04% | – |
| QCOR | New | QUESTCOR PHARMACEUTICALS INC | $36,996,000 | – | 400,000 | – | 3.63% | – |
| INSM | New | INSMED INC | $35,964,000 | – | 1,800,000 | – | 3.53% | – |
| DYAX | New | DYAX CORP | $26,022,000 | – | 2,710,598 | – | 2.55% | – |
| ZBH | New | ZIMMER HLDGS INC | $25,186,000 | – | 242,500 | – | 2.47% | – |
| SHPG | New | SHIRE PLCsponsored adr | $21,194,000 | – | 90,000 | – | 2.08% | – |
| WAG | New | WALGREEN CO | $20,905,000 | – | 282,000 | – | 2.05% | – |
| XNCR | New | XENCOR INC | $20,226,000 | – | 1,740,621 | – | 1.98% | – |
| HRTX | New | HERON THERAPEUTICS INC | $20,138,000 | – | 1,634,555 | – | 1.98% | – |
| TSRO | New | TESARO INC | $19,816,000 | – | 636,956 | – | 1.94% | – |
| LBIO | New | LION BIOTECHNOLOGIES | $19,273,000 | – | 3,011,549 | – | 1.89% | – |
| NEPT | New | NEPTUNE TECHNOLOGIES BIORESO | $18,493,000 | – | 6,700,444 | – | 1.81% | – |
| PTCT | New | PTC THERAPEUTICS INC | $17,559,000 | – | 671,736 | – | 1.72% | – |
| OPHT | New | OPHTHOTECH CORP | $15,717,000 | – | 371,469 | – | 1.54% | – |
| EXAS | New | EXACT SCIENCES CORP | $15,348,000 | – | 901,250 | – | 1.51% | – |
| RTRX | New | RETROPHIN INC | $14,960,000 | – | 1,274,292 | – | 1.47% | – |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $14,751,000 | – | 653,000 | – | 1.45% | – |
| MYL | New | MYLAN INC | $14,566,000 | – | 282,500 | – | 1.43% | – |
| RLYP | New | RELYPSA INC | $14,509,000 | – | 596,605 | – | 1.42% | – |
| SGMO | New | SANGAMO BIOSCIENCES INC | $12,216,000 | – | 800,000 | – | 1.20% | – |
| FLML | New | FLAMEL TECHNOLOGIES SAsponsored adr | $12,000,000 | – | 800,000 | – | 1.18% | – |
| HCA | New | HCA HOLDINGS INC | $11,152,000 | – | 197,806 | – | 1.09% | – |
| PRTA | New | PROTHENA CORP PLC | $10,895,000 | – | 483,162 | – | 1.07% | – |
| AET | New | AETNA INC NEW | $10,646,000 | – | 131,308 | – | 1.04% | – |
| XLRN | New | ACCELERON PHARMA INC | $10,191,000 | – | 300,000 | – | 1.00% | – |
| MGNX | New | MACROGENICS INC | $9,383,000 | – | 431,803 | – | 0.92% | – |
| ANAC | New | ANACOR PHARMACEUTICALS INC | $9,375,000 | – | 528,776 | – | 0.92% | – |
| ITMN | New | INTERMUNE INC | $9,272,000 | – | 210,000 | – | 0.91% | – |
| VSAR | New | VERSARTIS INC | $8,855,000 | – | 315,796 | – | 0.87% | – |
| RCPT | New | RECEPTOS INC | $8,733,000 | – | 205,000 | – | 0.86% | – |
| AGN | New | ALLERGAN INC | $8,461,000 | – | 50,000 | – | 0.83% | – |
| BDSI | New | BIODELIVERY SCIENCES INTL IN | $8,449,000 | – | 700,000 | – | 0.83% | – |
| MDT | New | MEDTRONIC INC | $8,289,000 | – | 130,000 | – | 0.81% | – |
| TRXC | New | TRANSENTERIX INC | $6,552,000 | – | 1,300,000 | – | 0.64% | – |
| ARWR | New | ARROWHEAD RESH CORP | $6,045,000 | – | 422,406 | – | 0.59% | – |
| RGDO | New | REGADO BIOSCIENCES INC | $5,839,000 | – | 860,000 | – | 0.57% | – |
| SPNC | New | SPECTRANETICS CORP | $5,568,000 | – | 243,354 | – | 0.55% | – |
| ICPT | New | INTERCEPT INCput | $4,733,000 | – | 20,000 | – | 0.46% | – |
| DSCI | New | DERMA SCIENCES INC | $4,698,000 | – | 406,437 | – | 0.46% | – |
| CNC | New | CENTENE CORP DEL | $4,537,000 | – | 60,000 | – | 0.44% | – |
| TRVN | New | TREVENA INC | $4,351,000 | – | 770,000 | – | 0.43% | – |
| AERI | New | ALLIQUA | $4,196,000 | – | 1,121,951 | – | 0.41% | – |
| CPRX | New | CATALYST PHARM PARTNERS INC | $3,795,000 | – | 1,500,000 | – | 0.37% | – |
| WAG | New | WALGREEN COcall | $3,707,000 | – | 50,000 | – | 0.36% | – |
| New | ARNO THERAPEUTICS | $3,621,000 | – | 2,034,721 | – | 0.36% | – | |
| AGTC | New | APPLIED GENETIC TECHNOL CORP | $3,395,000 | – | 146,978 | – | 0.33% | – |
| CMRX | New | CHIMERIX INC | $3,241,000 | – | 148,000 | – | 0.32% | – |
| AEGR | New | AEGERION PHARMACEUTICALS ORDcall | $3,209,000 | – | 100,000 | – | 0.32% | – |
| TSRO | New | TESARO INCput | $3,111,000 | – | 100,000 | – | 0.30% | – |
| ZLTQ | New | ZELTIQ AESTHETICS INC | $3,065,000 | – | 201,628 | – | 0.30% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INCput | $2,840,000 | – | 30,000 | – | 0.28% | – |
| MGCD | New | MGC DIAGNOSTICS CORP | $2,652,000 | – | 316,459 | – | 0.26% | – |
| QTNT | New | QUOTIENT LTD | $2,499,000 | – | 300,000 | – | 0.24% | – |
| ACST | New | ACASTI PHARMA INC | $2,437,000 | – | 2,566,785 | – | 0.24% | – |
| FPRX | New | FIVE PRIME THERAPEUTICS INC | $2,333,000 | – | 150,000 | – | 0.23% | – |
| F113PS | New | COVIDIEN PLC | $2,255,000 | – | 25,000 | – | 0.22% | – |
| KPTI | New | KARYOPHARM THERAPEUTICS INC | $2,125,000 | – | 45,643 | – | 0.21% | – |
| ACHN | New | ACHILLION PHARMACEUTICALS IN | $2,120,000 | – | 280,000 | – | 0.21% | – |
| GNVC | New | GENVEC INC | $2,107,000 | – | 820,000 | – | 0.21% | – |
| SNN | New | SMITH & NEPHEW PLCspdn adr new | $2,050,000 | – | 22,963 | – | 0.20% | – |
| UPI | New | UROPLASTY INC | $1,791,000 | – | 668,287 | – | 0.18% | – |
| LGND | New | LIGAND PHARMACEUTICALS INC | $1,734,000 | – | 27,843 | – | 0.17% | – |
| DRRX | New | DURECT CORP | $1,651,000 | – | 907,064 | – | 0.16% | – |
| New | ANTHERA PHARMACEUTICALS INC | $1,622,000 | – | 478,456 | – | 0.16% | – | |
| CSBR | New | CHAMPIONS ONCOLOGY | $1,625,000 | – | 1,625,744 | – | 0.16% | – |
| OREX | New | OREXIGEN THERAPEUTICS INC | $1,384,000 | – | 224,000 | – | 0.14% | – |
| EXEL | New | EXELIXIS INCcall | $1,356,000 | – | 400,000 | – | 0.13% | – |
| EPZM | New | EPIZYME INC | $1,326,000 | – | 42,602 | – | 0.13% | – |
| NLNK | New | NEWLINK GENETICS CORPcall | $1,328,000 | – | 50,000 | – | 0.13% | – |
| AQXP | New | AQUINOX PHARMACEUTICALS INC | $1,218,000 | – | 130,000 | – | 0.12% | – |
| ELOS | New | SYNERON MEDICAL LTD | $1,187,000 | – | 115,000 | – | 0.12% | – |
| INCY | New | INCYTE CORP | $1,129,000 | – | 20,000 | – | 0.11% | – |
| ATHX | New | ATHERSYS INC | $1,077,000 | – | 601,852 | – | 0.11% | – |
| OXGN | New | OXIGENE INC | $982,000 | – | 379,200 | – | 0.10% | – |
| ICAD | New | ICAD INC | $962,000 | – | 150,000 | – | 0.09% | – |
| ONTY | New | ONCOTHYREON INC | $949,000 | – | 292,779 | – | 0.09% | – |
| AKAOQ | New | ACHAOGEN INC | $838,000 | – | 60,000 | – | 0.08% | – |
| GLMD | New | GALMED PHARMACEUTICALS LTD | $731,000 | – | 75,000 | – | 0.07% | – |
| BOTA | New | BIOTA PHARMACEUTIALS INC | $722,000 | – | 253,400 | – | 0.07% | – |
| TBIO | New | TRANSGENOMIC INC | $687,000 | – | 183,957 | – | 0.07% | – |
| STEM | New | STEMCELLS INC | $551,000 | – | 271,600 | – | 0.05% | – |
| CLVS | New | CLOVIS ONCOLOGY INC | $452,000 | – | 10,917 | – | 0.04% | – |
| MDGN | New | MEDGENICS INC | $428,000 | – | 55,073 | – | 0.04% | – |
| BLRX | New | BIOLINERX LTDsponsored adr | $345,000 | – | 165,698 | – | 0.03% | – |
| HNT | New | HEALTH NET INC | $250,000 | – | 6,025 | – | 0.02% | – |
| UHS | New | UNIVERSAL HLTH SVCS INCcl b | $214,000 | – | 2,236 | – | 0.02% | – |
| ARNA | New | ARENA PHARMACEUTICALS INCput | $176,000 | – | 30,000 | – | 0.02% | – |
| RDNT | New | RADNET INC | $152,000 | – | 22,975 | – | 0.02% | – |
| SSH | New | SUNSHINE HEART INC | $140,000 | – | 25,000 | – | 0.01% | – |
| ICLR | New | ICON PLC | $115,000 | – | 2,440 | – | 0.01% | – |
| ENSG | New | ENSIGN GROUP INC | $109,000 | – | 3,509 | – | 0.01% | – |
| EXAC | New | EXACTECH INC | $113,000 | – | 4,464 | – | 0.01% | – |
| PMC | New | PHARMERICA CORP | $98,000 | – | 3,441 | – | 0.01% | – |
| BCR | New | BARD C R INC | $97,000 | – | 676 | – | 0.01% | – |
| MRGE | New | MERGE HEALTHCARE INC | $99,000 | – | 43,478 | – | 0.01% | – |
| SMA | New | SYMMETRY MED INC | $99,000 | – | 11,148 | – | 0.01% | – |
| MOH | New | MOLINA HEALTHCARE INC | $106,000 | – | 2,380 | – | 0.01% | – |
| MDAS | New | MEDASSETS INC | $101,000 | – | 4,429 | – | 0.01% | – |
| GTS | New | TRIPLE-S MGMT CORPcl b | $105,000 | – | 5,880 | – | 0.01% | – |
| AFAM | New | ALMOST FAMILY INC | $104,000 | – | 4,708 | – | 0.01% | – |
| WCG | New | WELLCARE HEALTH PLANS INC | $97,000 | – | 1,302 | – | 0.01% | – |
| MCK | New | MCKESSON CORP | $99,000 | – | 530 | – | 0.01% | – |
| MGLN | New | MAGELLAN HEALTH INC | $102,000 | – | 1,642 | – | 0.01% | – |
| GTIV | New | GENTIVA HEALTH SERVICES INC | $106,000 | – | 7,052 | – | 0.01% | – |
| BSTC | New | BIOSPECIFICS TECHNOLOGIES CO | $100,000 | – | 3,700 | – | 0.01% | – |
| PDLI | New | PDL BIOPHARMA INC | $99,000 | – | 10,183 | – | 0.01% | – |
| CRL | New | CHARLES RIV LABS INTL INC | $100,000 | – | 1,860 | – | 0.01% | – |
| HUM | New | HUMANA INC | $103,000 | – | 803 | – | 0.01% | – |
| CBPO | New | CHINA BIOLOGIC PRODS INC | $107,000 | – | 2,400 | – | 0.01% | – |
| Q | New | QUINTILES TRANSNATIO HLDGS I | $100,000 | – | 1,875 | – | 0.01% | – |
| AMSG | New | AMSURG CORP | $90,000 | – | 1,980 | – | 0.01% | – |
Q4 2013
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CBMXW | Exit | COMBIMATRIX CORPORATION*w exp 05/01/201 | $0 | – | -10,000 | – | 0.00% | – |
| AXGN | Exit | AXOGEN INC | $0 | – | -9,000 | – | -0.00% | – |
| CUTR | Exit | CUTERA INC | $0 | – | -24,800 | – | -0.01% | – |
| ZLTQ | Exit | ZELTIQ AESTHETICS INC | $0 | – | -27,406 | – | -0.01% | – |
| KYTH | Exit | KYTHERA BIOPHARMACEUTICALS I | $0 | – | -5,530 | – | -0.01% | – |
| MD | Exit | MEDNAX INC | $0 | – | -2,750 | – | -0.01% | – |
| WOOF | Exit | VCA ANTECH INC | $0 | – | -9,430 | – | -0.01% | – |
| HNGR | Exit | HANGER INC | $0 | – | -8,160 | – | -0.01% | – |
| DVA | Exit | DAVITA HEALTHCARE PARTNERS I | $0 | – | -4,620 | – | -0.01% | – |
| ALR | Exit | ALERE INC | $0 | – | -8,860 | – | -0.01% | – |
| CVS | Exit | CVS CAREMARK CORPORATION | $0 | – | -4,600 | – | -0.01% | – |
| AMSG | Exit | AMSURG CORP | $0 | – | -6,830 | – | -0.01% | – |
| MGLN | Exit | MAGELLAN HEALTH SVCS INC | $0 | – | -4,580 | – | -0.01% | – |
| AET | Exit | AETNA INC NEW | $0 | – | -4,140 | – | -0.01% | – |
| MOH | Exit | MOLINA HEALTHCARE INC | $0 | – | -7,180 | – | -0.01% | – |
| HLS | Exit | HEALTHSOUTH CORP | $0 | – | -8,380 | – | -0.01% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -5,400 | – | -0.01% | – |
| CNC | Exit | CENTENE CORP DEL | $0 | – | -4,710 | – | -0.01% | – |
| CYH | Exit | COMMUNITY HEALTH SYS INC NEW | $0 | – | -6,830 | – | -0.01% | – |
| OCR | Exit | OMNICARE INC | $0 | – | -5,050 | – | -0.01% | – |
| LPNT | Exit | LIFEPOINT HOSPITALS INC | $0 | – | -5,990 | – | -0.01% | – |
| FURX | Exit | FURIEX PHARMACEUTICALS INC | $0 | – | -10,000 | – | -0.02% | – |
| XNPT | Exit | XENOPORT INC | $0 | – | -96,500 | – | -0.02% | – |
| NAVB | Exit | NAVIDEA BIOPHARMACEUTICALS Iput | $0 | – | -233,000 | – | -0.02% | – |
| HTWR | Exit | HEARTWARE INTL INC | $0 | – | -10,000 | – | -0.03% | – |
| ACST | Exit | ACASTI PHARMA INC | $0 | – | -308,772 | – | -0.03% | – |
| STEM | Exit | STEMCELLS INC | $0 | – | -463,200 | – | -0.03% | – |
| ASTX | Exit | ASTEX PHARMACEUTICALS INC | $0 | – | -94,196 | – | -0.03% | – |
| VICL | Exit | VICAL INCcall | $0 | – | -800,000 | – | -0.04% | – |
| NSPH | Exit | NANOSPHERE INC | $0 | – | -679,000 | – | -0.06% | – |
| RGEN | Exit | REPLIGEN CORPput | $0 | – | -136,600 | – | -0.06% | – |
| AVNR | Exit | AVANIR PHARMACEUTICALS INCput | $0 | – | -386,000 | – | -0.07% | – |
| TBIO | Exit | TRANSGENOMIC INC | $0 | – | -4,415,000 | – | -0.07% | – |
| PGNX | Exit | PROGENICS PHARMACEUTICALS IN | $0 | – | -338,136 | – | -0.07% | – |
| AMRN | Exit | AMARIN CORP PLCcall | $0 | – | -289,600 | – | -0.08% | – |
| ONTY | Exit | ONCOTHYREON INC | $0 | – | -965,000 | – | -0.08% | – |
| UPI | Exit | UROPLASTY INC | $0 | – | -607,978 | – | -0.08% | – |
| VNDA | Exit | VANDA PHARMACEUTICALS INCput | $0 | – | -193,000 | – | -0.09% | – |
| TKMR | Exit | TEKMIRA PHARMACEUTICALS CORP | $0 | – | -318,618 | – | -0.09% | – |
| MDGN | Exit | MEDGENICS INC | $0 | – | -300,000 | – | -0.10% | – |
| MYGN | Exit | MYRIAD GENETICS INCcall | $0 | – | -116,600 | – | -0.11% | – |
| BCRX | Exit | BIOCRYST PHARMACEUTICALS | $0 | – | -381,176 | – | -0.11% | – |
| MNKD | Exit | MANNKIND CORP | $0 | – | -579,000 | – | -0.14% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEWcall | $0 | – | -96,600 | – | -0.14% | – |
| ANTH | Exit | ANTHERA PHARMACEUTICALS INC | $0 | – | -862,912 | – | -0.14% | – |
| MGCD | Exit | MGC DIAGNOSTICS CORP | $0 | – | -348,898 | – | -0.16% | – |
| KERX | Exit | KERYX BIOPHARMACEUTICALS INC | $0 | – | -400,000 | – | -0.17% | – |
| DXCM | Exit | DEXCOM INC | $0 | – | -145,100 | – | -0.17% | – |
| ECYT | Exit | ENDOCYTE INCput | $0 | – | -386,000 | – | -0.21% | – |
| SPNC | Exit | SPECTRANETICS CORP | $0 | – | -308,158 | – | -0.21% | – |
| VVUS | Exit | VIVUS INCput | $0 | – | -579,000 | – | -0.22% | – |
| CSBR | Exit | CHAMPIONS ONCOLOGY INC RSTD | $0 | – | -3,116,488 | – | -0.22% | – |
| NBS | Exit | NEOSTEM INC | $0 | – | -663,186 | – | -0.23% | – |
| MDVN | Exit | MEDIVATION INC | $0 | – | -96,500 | – | -0.24% | – |
| MZOR | Exit | MAZOR ROBOTICS LTDsponsored ads | $0 | – | -354,156 | – | -0.25% | – |
| VSTM | Exit | VERASTEM INC | $0 | – | -482,130 | – | -0.25% | – |
| PSDV | Exit | PSIVIDA CORP | $0 | – | -1,544,000 | – | -0.26% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INCput | $0 | – | -579,000 | – | -0.27% | – |
| INFI | Exit | INFINITY PHARMACEUTICALS INC | $0 | – | -390,310 | – | -0.28% | – |
| ANIK | Exit | ANIKA THERAPEUTICS INC | $0 | – | -288,134 | – | -0.28% | – |
| ATHX | Exit | ATHERSYS INC | $0 | – | -4,300,234 | – | -0.29% | – |
| CNDO | Exit | CORONADO BIOSCIENCES INCput | $0 | – | -1,003,800 | – | -0.29% | – |
| ARRY | Exit | ARRAY BIOPHARMA INC | $0 | – | -1,145,740 | – | -0.29% | – |
| STML | Exit | STEMLINE THERAPEUTICS INC | $0 | – | -180,416 | – | -0.34% | – |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -1,475,010 | – | -0.38% | – |
| ITMN | Exit | INTERMUNE INC | $0 | – | -600,000 | – | -0.38% | – |
| RPRX | Exit | REPROS THERAPEUTICS INCcall | $0 | – | -386,000 | – | -0.43% | – |
| VNDA | Exit | VANDA PHARMACEUTICALS INCcall | $0 | – | -965,200 | – | -0.44% | – |
| AMRN | Exit | AMARIN CORP PLCput | $0 | – | -1,737,000 | – | -0.45% | – |
| ECYT | Exit | ENDOCYTE INC | $0 | – | -837,430 | – | -0.46% | – |
| ISIS | Exit | ISIS PHARMACEUTICALS INC | $0 | – | -385,600 | – | -0.60% | – |
| WCG | Exit | WELLCARE HEALTH PLANS INC | $0 | – | -264,162 | – | -0.76% | – |
| VNDA | Exit | VANDA PHARMACEUTICALS INC | $0 | – | -1,737,000 | – | -0.78% | – |
| P103PS | Exit | NPS PHARMACEUTICALS INC | $0 | – | -611,524 | – | -0.80% | – |
| WAG | Exit | WALGREEN CO | $0 | – | -375,740 | – | -0.83% | – |
| SGMO | Exit | SANGAMO BIOSCIENCES INC | $0 | – | -1,930,000 | – | -0.83% | – |
| CHTP | Exit | CHELSEA THERAPEUTICS INTL LT | $0 | – | -6,836,730 | – | -0.84% | – |
| AMGN | Exit | AMGEN INC | $0 | – | -183,350 | – | -0.84% | – |
| IWM | Exit | ISHARESput | $0 | – | -193,000 | – | -0.85% | – |
| ANAC | Exit | ANACOR PHARMACEUTICALS INC | $0 | – | -1,947,736 | – | -0.85% | – |
| CTIC | Exit | CELL THERAPEUTICS INC | $0 | – | -13,989,346 | – | -0.93% | – |
| DYAX | Exit | DYAX CORP | $0 | – | -3,385,824 | – | -0.96% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -389,402 | – | -0.98% | – |
| SNTS | Exit | SANTARUS INC | $0 | – | -1,064,486 | – | -0.99% | – |
| F113PS | Exit | COVIDIEN PLC | $0 | – | -422,490 | – | -1.06% | – |
| CSU | Exit | CAPITAL SR LIVING CORP | $0 | – | -1,228,178 | – | -1.07% | – |
| PCRX | Exit | PACIRA PHARMACEUTICALS INC | $0 | – | -544,068 | – | -1.08% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INCput | $0 | – | -5,116,200 | – | -1.11% | – |
| HNT | Exit | HEALTH NET INC | $0 | – | -907,560 | – | -1.18% | – |
| SNTA | Exit | SYNTA PHARMACEUTICALS CORP | $0 | – | -4,762,472 | – | -1.24% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -1,221,230 | – | -1.38% | – |
| NEPT | Exit | NEPTUNE TECHNOLOGIES BIORESO | $0 | – | -10,767,714 | – | -1.41% | – |
| CI | Exit | CIGNA CORPORATION | $0 | – | -445,696 | – | -1.41% | – |
| MYL | Exit | MYLAN INC | $0 | – | -920,610 | – | -1.45% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -3,496,628 | – | -1.70% | – |
| QCOR | Exit | QUESTCOR PHARMACEUTICALS INC | $0 | – | -752,700 | – | -1.80% | – |
| IBB | Exit | ISHARESput | $0 | – | -289,600 | – | -2.50% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -904,190 | – | -2.82% | – |
| RPRX | Exit | REPROS THERAPEUTICS INC | $0 | – | -2,963,466 | – | -3.27% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -8,541,408 | – | -3.98% | – |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -1,728,140 | – | -4.47% | – |
| CELG | Exit | CELGENE CORP | $0 | – | -729,238 | – | -4.63% | – |
| TSRO | Exit | TESARO INC | $0 | – | -3,027,288 | – | -4.83% | – |
| ACRX | Exit | ACELRX PHARMACEUTICALS INC | $0 | – | -11,716,800 | – | -5.20% | – |
| ONXX | Exit | ONYX PHARMACEUTICALS INC | $0 | – | -1,113,888 | – | -5.72% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -23,044,138 | – | -9.33% | – |
| AEGR | Exit | AEGERION PHARMACEUTICALS INC | $0 | – | -4,656,682 | – | -16.44% | – |
Q3 2013
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| AEGR | Buy | AEGERION PHARMACEUTICALS INC | $399,310,000 | +76.4% | 4,656,682 | +30.3% | 16.44% | -28.0% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $226,641,000 | +118.9% | 23,044,138 | +746.6% | 9.33% | -10.6% |
| ONXX | New | ONYX PHARMACEUTICALS INC | $138,902,000 | – | 1,113,888 | – | 5.72% | – |
| ACRX | Buy | ACELRX PHARMACEUTICALS INC | $126,308,000 | +172.1% | 11,716,800 | +133.9% | 5.20% | +11.1% |
| TSRO | Buy | TESARO INC | $117,278,000 | +289.1% | 3,027,288 | +228.9% | 4.83% | +58.9% |
| CELG | Buy | CELGENE CORP | $112,402,000 | +898.2% | 729,238 | +657.6% | 4.63% | +307.7% |
| GILD | Buy | GILEAD SCIENCES INC | $108,648,000 | +168.8% | 1,728,140 | +119.2% | 4.47% | +9.7% |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $96,688,000 | +42.2% | 8,541,408 | +68.1% | 3.98% | -41.9% |
| RPRX | Buy | REPROS THERAPEUTICS INC | $79,420,000 | +2272.9% | 2,963,466 | +1533.4% | 3.27% | +867.2% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $68,554,000 | +233.8% | 904,190 | +252.4% | 2.82% | +36.3% |
| IBB | New | ISHARESput | $60,700,000 | – | 289,600 | – | 2.50% | – |
| QCOR | Buy | QUESTCOR PHARMACEUTICALS INC | $43,656,000 | +2177.3% | 752,700 | +1684.2% | 1.80% | +831.1% |
| EXAS | Buy | EXACT SCIENCES CORP | $41,260,000 | +79.8% | 3,496,628 | +112.0% | 1.70% | -26.6% |
| MYL | New | MYLAN INC | $35,140,000 | – | 920,610 | – | 1.45% | – |
| CI | Buy | CIGNA CORPORATION | $34,256,000 | +163023.8% | 445,696 | +153588.3% | 1.41% | +70400.0% |
| NEPT | Buy | NEPTUNE TECHNOLOGIES BIORESO | $34,240,000 | +94.5% | 10,767,714 | +98.6% | 1.41% | -20.6% |
| ACAD | Buy | ACADIA PHARMACEUTICALS INC | $33,548,000 | +154.4% | 1,221,230 | +68.1% | 1.38% | +3.8% |
| SNTA | Buy | SYNTA PHARMACEUTICALS CORP | $30,052,000 | +123.6% | 4,762,472 | +76.8% | 1.24% | -8.7% |
| HNT | New | HEALTH NET INC | $28,770,000 | – | 907,560 | – | 1.18% | – |
| ARNA | New | ARENA PHARMACEUTICALS INCput | $26,962,000 | – | 5,116,200 | – | 1.11% | – |
| PCRX | New | PACIRA PHARMACEUTICALS INC | $26,156,000 | – | 544,068 | – | 1.08% | – |
| CSU | Buy | CAPITAL SR LIVING CORP | $25,976,000 | +21.9% | 1,228,178 | +37.8% | 1.07% | -50.2% |
| F113PS | Buy | COVIDIEN PLC | $25,746,000 | +506.9% | 422,490 | +525.9% | 1.06% | +147.7% |
| SNTS | Buy | SANTARUS INC | $24,046,000 | +82.8% | 1,064,486 | +70.3% | 0.99% | -25.4% |
| CLVS | Buy | CLOVIS ONCOLOGY INC | $23,676,000 | +151.0% | 389,402 | +176.5% | 0.98% | +2.5% |
| DYAX | Buy | DYAX CORP | $23,226,000 | +289.7% | 3,385,824 | +96.6% | 0.96% | +59.1% |
| CTIC | New | CELL THERAPEUTICS INC | $22,676,000 | – | 13,989,346 | – | 0.93% | – |
| ANAC | Buy | ANACOR PHARMACEUTICALS INC | $20,684,000 | +534.9% | 1,947,736 | +234.2% | 0.85% | +158.7% |
| IWM | New | ISHARESput | $20,576,000 | – | 193,000 | – | 0.85% | – |
| AMGN | New | AMGEN INC | $20,522,000 | – | 183,350 | – | 0.84% | – |
| CHTP | Buy | CHELSEA THERAPEUTICS INTL LT | $20,440,000 | +90.8% | 6,836,730 | +46.8% | 0.84% | -22.1% |
| SGMO | New | SANGAMO BIOSCIENCES INC | $20,246,000 | – | 1,930,000 | – | 0.83% | – |
| WAG | New | WALGREEN CO | $20,214,000 | – | 375,740 | – | 0.83% | – |
| P103PS | Buy | NPS PHARMACEUTICALS INC | $19,452,000 | +128.9% | 611,524 | +8.7% | 0.80% | -6.5% |
| VNDA | New | VANDA PHARMACEUTICALS INC | $19,020,000 | – | 1,737,000 | – | 0.78% | – |
| WCG | Buy | WELLCARE HEALTH PLANS INC | $18,422,000 | +87623.8% | 264,162 | +68513.5% | 0.76% | +37800.0% |
| ISIS | New | ISIS PHARMACEUTICALS INC | $14,476,000 | – | 385,600 | – | 0.60% | – |
| ECYT | Buy | ENDOCYTE INC | $11,162,000 | +1136.1% | 837,430 | +1117.1% | 0.46% | +405.5% |
| AMRN | New | AMARIN CORP PLCput | $10,978,000 | – | 1,737,000 | – | 0.45% | – |
| VNDA | New | VANDA PHARMACEUTICALS INCcall | $10,568,000 | – | 965,200 | – | 0.44% | – |
| RPRX | New | REPROS THERAPEUTICS INCcall | $10,344,000 | – | 386,000 | – | 0.43% | – |
| ITMN | Buy | INTERMUNE INC | $9,228,000 | +219.8% | 600,000 | +100.0% | 0.38% | +30.6% |
| IMMU | Buy | IMMUNOMEDICS INC | $9,146,000 | +127.5% | 1,475,010 | +99.6% | 0.38% | -6.9% |
| STML | Sell | STEMLINE THERAPEUTICS INC | $8,172,000 | -42.1% | 180,416 | -69.5% | 0.34% | -76.4% |
| ARRY | Buy | ARRAY BIOPHARMA INC | $7,126,000 | +7997.7% | 1,145,740 | +5830.3% | 0.29% | +3155.6% |
| CNDO | New | CORONADO BIOSCIENCES INCput | $7,038,000 | – | 1,003,800 | – | 0.29% | – |
| ATHX | Buy | ATHERSYS INC | $7,052,000 | +22.1% | 4,300,234 | +23.6% | 0.29% | -50.2% |
| ANIK | New | ANIKA THERAPEUTICS INC | $6,884,000 | – | 288,134 | – | 0.28% | – |
| INFI | Buy | INFINITY PHARMACEUTICALS INC | $6,804,000 | +275.3% | 390,310 | +248.7% | 0.28% | +53.0% |
| NBIX | New | NEUROCRINE BIOSCIENCES INCput | $6,554,000 | – | 579,000 | – | 0.27% | – |
| PSDV | New | PSIVIDA CORP | $6,346,000 | – | 1,544,000 | – | 0.26% | – |
| VSTM | New | VERASTEM INC | $6,002,000 | – | 482,130 | – | 0.25% | – |
| MZOR | New | MAZOR ROBOTICS LTDsponsored ads | $5,986,000 | – | 354,156 | – | 0.25% | – |
| MDVN | New | MEDIVATION INC | $5,784,000 | – | 96,500 | – | 0.24% | – |
| NBS | New | NEOSTEM INC | $5,670,000 | – | 663,186 | – | 0.23% | – |
| CSBR | Buy | CHAMPIONS ONCOLOGY INC RSTD | $5,452,000 | +174.1% | 3,116,488 | +72.3% | 0.22% | +11.4% |
| VVUS | New | VIVUS INCput | $5,384,000 | – | 579,000 | – | 0.22% | – |
| SPNC | Sell | SPECTRANETICS CORP | $5,178,000 | -17.9% | 308,158 | -8.8% | 0.21% | -66.5% |
| ECYT | New | ENDOCYTE INCput | $5,146,000 | – | 386,000 | – | 0.21% | – |
| DXCM | New | DEXCOM INC | $4,094,000 | – | 145,100 | – | 0.17% | – |
| KERX | Buy | KERYX BIOPHARMACEUTICALS INC | $4,036,000 | +979.1% | 400,000 | +700.0% | 0.17% | +336.8% |
| MGCD | Buy | MGC DIAGNOSTICS CORP | $3,820,000 | +162.2% | 348,898 | +100.0% | 0.16% | +6.8% |
| ANTH | New | ANTHERA PHARMACEUTICALS INC | $3,468,000 | – | 862,912 | – | 0.14% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEWcall | $3,422,000 | – | 96,600 | – | 0.14% | – |
| MNKD | New | MANNKIND CORP | $3,300,000 | – | 579,000 | – | 0.14% | – |
| BCRX | New | BIOCRYST PHARMACEUTICALS | $2,774,000 | – | 381,176 | – | 0.11% | – |
| MYGN | New | MYRIAD GENETICS INCcall | $2,740,000 | – | 116,600 | – | 0.11% | – |
| MDGN | Buy | MEDGENICS INC | $2,340,000 | +310.5% | 300,000 | +100.0% | 0.10% | +68.4% |
| TKMR | Buy | TEKMIRA PHARMACEUTICALS CORP | $2,224,000 | +78.8% | 318,618 | +18.0% | 0.09% | -26.4% |
| VNDA | New | VANDA PHARMACEUTICALS INCput | $2,114,000 | – | 193,000 | – | 0.09% | – |
| UPI | Buy | UROPLASTY INC | $2,012,000 | +225.0% | 607,978 | +103.3% | 0.08% | +33.9% |
| ONTY | New | ONCOTHYREON INC | $1,988,000 | – | 965,000 | – | 0.08% | – |
| AMRN | New | AMARIN CORP PLCcall | $1,830,000 | – | 289,600 | – | 0.08% | – |
| PGNX | Buy | PROGENICS PHARMACEUTICALS IN | $1,698,000 | +24.1% | 338,136 | +10.3% | 0.07% | -49.3% |
| TBIO | Buy | TRANSGENOMIC INC | $1,676,000 | +89.8% | 4,415,000 | +100.0% | 0.07% | -22.5% |
| AVNR | New | AVANIR PHARMACEUTICALS INCput | $1,632,000 | – | 386,000 | – | 0.07% | – |
| RGEN | New | REPLIGEN CORPput | $1,514,000 | – | 136,600 | – | 0.06% | – |
| NSPH | New | NANOSPHERE INC | $1,358,000 | – | 679,000 | – | 0.06% | – |
| VICL | New | VICAL INCcall | $1,000,000 | – | 800,000 | – | 0.04% | – |
| ASTX | Sell | ASTEX PHARMACEUTICALS INC | $800,000 | -88.2% | 94,196 | -94.3% | 0.03% | -95.2% |
| STEM | Buy | STEMCELLS INC | $778,000 | +103.7% | 463,200 | +100.0% | 0.03% | -17.9% |
| HTWR | New | HEARTWARE INTL INC | $732,000 | – | 10,000 | – | 0.03% | – |
| ACST | New | ACASTI PHARMA INC | $732,000 | – | 308,772 | – | 0.03% | – |
| NAVB | New | NAVIDEA BIOPHARMACEUTICALS Iput | $618,000 | – | 233,000 | – | 0.02% | – |
| XNPT | New | XENOPORT INC | $548,000 | – | 96,500 | – | 0.02% | – |
| FURX | New | FURIEX PHARMACEUTICALS INC | $440,000 | – | 10,000 | – | 0.02% | – |
| AZN | New | ASTRAZENECA PLCsponsored adr | $280,000 | – | 5,400 | – | 0.01% | – |
| OCR | Buy | OMNICARE INC | $280,000 | +1300.0% | 5,050 | +1088.2% | 0.01% | +500.0% |
| CNC | New | CENTENE CORP DEL | $302,000 | – | 4,710 | – | 0.01% | – |
| CYH | New | COMMUNITY HEALTH SYS INC NEW | $284,000 | – | 6,830 | – | 0.01% | – |
| LPNT | New | LIFEPOINT HOSPITALS INC | $280,000 | – | 5,990 | – | 0.01% | – |
| HLS | Buy | HEALTHSOUTH CORP | $288,000 | +1340.0% | 8,380 | +1105.8% | 0.01% | +500.0% |
| DVA | New | DAVITA HEALTHCARE PARTNERS I | $262,000 | – | 4,620 | – | 0.01% | – |
| CVS | New | CVS CAREMARK CORPORATION | $262,000 | – | 4,600 | – | 0.01% | – |
| HNGR | Buy | HANGER INC | $276,000 | +1280.0% | 8,160 | +1195.2% | 0.01% | +450.0% |
| WOOF | Buy | VCA ANTECH INC | $258,000 | +1190.0% | 9,430 | +1109.0% | 0.01% | +450.0% |
| AMSG | Buy | AMSURG CORP | $272,000 | +1260.0% | 6,830 | +1108.8% | 0.01% | +450.0% |
| MD | Buy | MEDNAX INC | $276,000 | +1214.3% | 2,750 | +1122.2% | 0.01% | +450.0% |
| ALR | Buy | ALERE INC | $270,000 | +1250.0% | 8,860 | +1007.5% | 0.01% | +450.0% |
| AET | Sell | AETNA INC NEW | $266,000 | -96.3% | 4,140 | -96.3% | 0.01% | -98.5% |
| MOH | Buy | MOLINA HEALTHCARE INC | $256,000 | +1180.0% | 7,180 | +1205.5% | 0.01% | +450.0% |
| MGLN | Buy | MAGELLAN HEALTH SVCS INC | $274,000 | +1270.0% | 4,580 | +1154.8% | 0.01% | +450.0% |
| KYTH | New | KYTHERA BIOPHARMACEUTICALS I | $252,000 | – | 5,530 | – | 0.01% | – |
| ZLTQ | New | ZELTIQ AESTHETICS INC | $248,000 | – | 27,406 | – | 0.01% | – |
| CUTR | Sell | CUTERA INC | $220,000 | -47.7% | 24,800 | -48.2% | 0.01% | -78.6% |
| AXGN | New | AXOGEN INC | $40,000 | – | 9,000 | – | 0.00% | – |
| CBMXW | Buy | COMBIMATRIX CORPORATION*w exp 05/01/201 | $4,000 | +300.0% | 10,000 | +100.0% | 0.00% | – |
| ENDP | Exit | ENDO HEALTH SOLUTIONS INC | $0 | – | -530 | – | -0.00% | – |
| DGX | Exit | QUEST DIAGNOSTICS INC | $0 | – | -325 | – | -0.00% | – |
| MDAS | Exit | MEDASSETS INC | $0 | – | -1,150 | – | -0.00% | – |
| V107SC | Exit | WELLPOINT INC | $0 | – | -255 | – | -0.00% | – |
| UNH | Exit | UNITEDHEALTH GROUP INC | $0 | – | -315 | – | -0.00% | – |
| HRC | Exit | HILL ROM HLDGS INC | $0 | – | -590 | – | -0.00% | – |
| HMA | Exit | HEALTH MGMT ASSOC INC NEWcl a | $0 | – | -1,265 | – | -0.00% | – |
| NAVB | Exit | NAVIDEA BIOPHARMACEUTICALS Iput | $0 | – | -20,000 | – | -0.01% | – |
| SNSS | Exit | SUNESIS PHARMACEUTICALS INC | $0 | – | -58,010 | – | -0.03% | – |
| EPZM | Exit | EPIZYME INC | $0 | – | -18,000 | – | -0.05% | – |
| LPDX | Exit | LIPOSCIENCE INC | $0 | – | -82,292 | – | -0.06% | – |
| BMR | Exit | BIOMED REALTY TRUST INC | $0 | – | -50,000 | – | -0.10% | – |
| CYCC | Exit | CYCLACEL PHARMACEUTICALS INC | $0 | – | -350,000 | – | -0.10% | – |
| AMRN | Exit | AMARIN CORP PLCput | $0 | – | -193,000 | – | -0.11% | – |
| VICL | Exit | VICAL INCcall | $0 | – | -400,000 | – | -0.13% | – |
| VPHM | Exit | VIROPHARMA INC | $0 | – | -48,300 | – | -0.14% | – |
| CEMP | Exit | CEMPRA INC | $0 | – | -200,000 | – | -0.16% | – |
| SGEN | Exit | SEATTLE GENETICS INCput | $0 | – | -50,000 | – | -0.16% | – |
| ANTH | Exit | ANTHERA PHARMACEUTICALS INC | $0 | – | -3,451,655 | – | -0.16% | – |
| NBS | Exit | NEOSTEM INC | $0 | – | -3,315,938 | – | -0.19% | – |
| BDSI | Exit | BIODELIVERY SCIENCES INTL IN | $0 | – | -477,600 | – | -0.20% | – |
| QCOR | Exit | QUESTCOR PHARMACEUTICALS INCcall | $0 | – | -50,000 | – | -0.23% | – |
| GILD | Exit | GILEAD SCIENCES INCput | $0 | – | -48,300 | – | -0.25% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INCput | $0 | – | -393,200 | – | -0.30% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INCput | $0 | – | -300,000 | – | -0.40% | – |
| SQNM | Exit | SEQUENOM INC | $0 | – | -985,180 | – | -0.42% | – |
| KMDA | Exit | KAMADA LTD | $0 | – | -394,860 | – | -0.44% | – |
| CRIS | Exit | CURIS INC | $0 | – | -1,392,564 | – | -0.45% | – |
| ELN | Exit | ELAN PLCadr | $0 | – | -483,000 | – | -0.69% | – |
| OPTR | Exit | OPTIMER PHARMACEUTICALS INCput | $0 | – | -496,500 | – | -0.72% | – |
| SHPG | Exit | SHIRE PLCsponsored adr | $0 | – | -80,800 | – | -0.78% | – |
| SLXP | Exit | SALIX PHARMACEUTICALS INC | $0 | – | -148,250 | – | -0.99% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INCcall | $0 | – | -275,000 | – | -1.06% | – |
| HCA | Exit | HCA HOLDINGS INC | $0 | – | -308,560 | – | -1.12% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INCput | $0 | – | -393,000 | – | -1.51% | – |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -139,310 | – | -3.16% | – |
| IBB | Exit | ISHARES TRput | $0 | – | -269,400 | – | -4.72% | – |
| BIIB | Exit | BIOGEN IDEC INC | $0 | – | -231,282 | – | -5.02% | – |
Q2 2013
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| AEGR | New | AEGERION PHARMACEUTICALS INC | $226,341,000 | – | 3,573,426 | – | 22.82% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $103,521,000 | – | 2,722,088 | – | 10.44% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $67,993,000 | – | 5,081,717 | – | 6.86% | – |
| BIIB | New | BIOGEN IDEC INC | $49,772,000 | – | 231,282 | – | 5.02% | – |
| IBB | New | ISHARES TRput | $46,843,000 | – | 269,400 | – | 4.72% | – |
| ACRX | New | ACELRX PHARMACEUTICALS INC | $46,428,000 | – | 5,008,400 | – | 4.68% | – |
| GILD | New | GILEAD SCIENCES INC | $40,419,000 | – | 788,360 | – | 4.08% | – |
| REGN | New | REGENERON PHARMACEUTICALS | $31,328,000 | – | 139,310 | – | 3.16% | – |
| TSRO | New | TESARO INC | $30,137,000 | – | 920,494 | – | 3.04% | – |
| EXAS | New | EXACT SCIENCES CORP | $22,945,000 | – | 1,649,558 | – | 2.31% | – |
| CSU | New | CAPITAL SR LIVING CORP | $21,305,000 | – | 891,408 | – | 2.15% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $20,539,000 | – | 256,547 | – | 2.07% | – |
| NEPT | New | NEPTUNE TECHNOLOGIES BIORESO | $17,602,000 | – | 5,422,920 | – | 1.78% | – |
| SRPT | New | SAREPTA THERAPEUTICS INCput | $14,950,000 | – | 393,000 | – | 1.51% | – |
| STML | New | STEMLINE THERAPEUTICS INC | $14,105,000 | – | 591,650 | – | 1.42% | – |
| SNTA | New | SYNTA PHARMACEUTICALS CORP | $13,439,000 | – | 2,693,236 | – | 1.36% | – |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $13,188,000 | – | 726,629 | – | 1.33% | – |
| SNTS | New | SANTARUS INC | $13,156,000 | – | 625,000 | – | 1.33% | – |
| CELG | New | CELGENE CORP | $11,260,000 | – | 96,256 | – | 1.14% | – |
| HCA | New | HCA HOLDINGS INC | $11,127,000 | – | 308,560 | – | 1.12% | – |
| CHTP | New | CHELSEA THERAPEUTICS INTL LT | $10,714,000 | – | 4,658,680 | – | 1.08% | – |
| SRPT | New | SAREPTA THERAPEUTICS INCcall | $10,461,000 | – | 275,000 | – | 1.06% | – |
| SLXP | New | SALIX PHARMACEUTICALS INC | $9,807,000 | – | 148,250 | – | 0.99% | – |
| CLVS | New | CLOVIS ONCOLOGY INC | $9,433,000 | – | 140,827 | – | 0.95% | – |
| P103PS | New | NPS PHARMACEUTICALS INC | $8,498,000 | – | 562,400 | – | 0.86% | – |
| SHPG | New | SHIRE PLCsponsored adr | $7,685,000 | – | 80,800 | – | 0.78% | – |
| OPTR | New | OPTIMER PHARMACEUTICALS INCput | $7,184,000 | – | 496,500 | – | 0.72% | – |
| AET | New | AETNA INC NEW | $7,169,000 | – | 112,825 | – | 0.72% | – |
| ELN | New | ELAN PLCadr | $6,830,000 | – | 483,000 | – | 0.69% | – |
| ASTX | New | ASTEX PHARMACEUTICALS INC | $6,779,000 | – | 1,649,423 | – | 0.68% | – |
| SPNC | New | SPECTRANETICS CORP | $6,310,000 | – | 337,797 | – | 0.64% | – |
| DYAX | New | DYAX CORP | $5,960,000 | – | 1,722,502 | – | 0.60% | – |
| ATHX | New | ATHERSYS INC | $5,775,000 | – | 3,479,206 | – | 0.58% | – |
| CRIS | New | CURIS INC | $4,442,000 | – | 1,392,564 | – | 0.45% | – |
| KMDA | New | KAMADA LTD | $4,407,000 | – | 394,860 | – | 0.44% | – |
| F113PS | New | COVIDIEN PLC | $4,242,000 | – | 67,500 | – | 0.43% | – |
| SQNM | New | SEQUENOM INC | $4,148,000 | – | 985,180 | – | 0.42% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INCput | $4,014,000 | – | 300,000 | – | 0.40% | – |
| IMMU | New | IMMUNOMEDICS INC | $4,021,000 | – | 739,144 | – | 0.40% | – |
| RPRX | New | REPROS THERAPEUTICS INC | $3,347,000 | – | 181,430 | – | 0.34% | – |
| ANAC | New | ANACOR PHARMACEUTICALS INC | $3,258,000 | – | 582,835 | – | 0.33% | – |
| ARNA | New | ARENA PHARMACEUTICALS INCput | $3,028,000 | – | 393,200 | – | 0.30% | – |
| ITMN | New | INTERMUNE INC | $2,886,000 | – | 300,000 | – | 0.29% | – |
| GILD | New | GILEAD SCIENCES INCput | $2,476,000 | – | 48,300 | – | 0.25% | – |
| QCOR | New | QUESTCOR PHARMACEUTICALS INCcall | $2,272,000 | – | 50,000 | – | 0.23% | – |
| CSBR | New | CHAMPIONS ONCOLOGY INC RSTD | $1,989,000 | – | 1,808,244 | – | 0.20% | – |
| BDSI | New | BIODELIVERY SCIENCES INTL IN | $1,939,000 | – | 477,600 | – | 0.20% | – |
| QCOR | New | QUESTCOR PHARMACEUTICALS INC | $1,917,000 | – | 42,186 | – | 0.19% | – |
| NBS | New | NEOSTEM INC | $1,840,000 | – | 3,315,938 | – | 0.19% | – |
| INFI | New | INFINITY PHARMACEUTICALS INC | $1,813,000 | – | 111,940 | – | 0.18% | – |
| ANTH | New | ANTHERA PHARMACEUTICALS INC | $1,598,000 | – | 3,451,655 | – | 0.16% | – |
| SGEN | New | SEATTLE GENETICS INCput | $1,573,000 | – | 50,000 | – | 0.16% | – |
| CEMP | New | CEMPRA INC | $1,554,000 | – | 200,000 | – | 0.16% | – |
| MGCD | New | MGC DIAGNOSTICS CORP | $1,457,000 | – | 174,449 | – | 0.15% | – |
| VPHM | New | VIROPHARMA INC | $1,384,000 | – | 48,300 | – | 0.14% | – |
| PGNX | New | PROGENICS PHARMACEUTICALS IN | $1,368,000 | – | 306,650 | – | 0.14% | – |
| VICL | New | VICAL INCcall | $1,252,000 | – | 400,000 | – | 0.13% | – |
| TKMR | New | TEKMIRA PHARMACEUTICALS CORP | $1,244,000 | – | 270,000 | – | 0.12% | – |
| AMRN | New | AMARIN CORP PLCput | $1,119,000 | – | 193,000 | – | 0.11% | – |
| CYCC | New | CYCLACEL PHARMACEUTICALS INC | $1,033,000 | – | 350,000 | – | 0.10% | – |
| BMR | New | BIOMED REALTY TRUST INC | $1,012,000 | – | 50,000 | – | 0.10% | – |
| ECYT | New | ENDOCYTE INC | $903,000 | – | 68,806 | – | 0.09% | – |
| TBIO | New | TRANSGENOMIC INC | $883,000 | – | 2,207,500 | – | 0.09% | – |
| UPI | New | UROPLASTY INC | $619,000 | – | 299,113 | – | 0.06% | – |
| LPDX | New | LIPOSCIENCE INC | $575,000 | – | 82,292 | – | 0.06% | – |
| MDGN | New | MEDGENICS INC | $570,000 | – | 150,000 | – | 0.06% | – |
| EPZM | New | EPIZYME INC | $506,000 | – | 18,000 | – | 0.05% | – |
| CUTR | New | CUTERA INC | $421,000 | – | 47,869 | – | 0.04% | – |
| STEM | New | STEMCELLS INC | $382,000 | – | 231,600 | – | 0.04% | – |
| KERX | New | KERYX BIOPHARMACEUTICALS INC | $374,000 | – | 50,000 | – | 0.04% | – |
| SNSS | New | SUNESIS PHARMACEUTICALS INC | $301,000 | – | 58,010 | – | 0.03% | – |
| ARRY | New | ARRAY BIOPHARMA INC | $88,000 | – | 19,320 | – | 0.01% | – |
| NAVB | New | NAVIDEA BIOPHARMACEUTICALS Iput | $53,000 | – | 20,000 | – | 0.01% | – |
| UNH | New | UNITEDHEALTH GROUP INC | $21,000 | – | 315 | – | 0.00% | – |
| WOOF | New | VCA ANTECH INC | $20,000 | – | 780 | – | 0.00% | – |
| HRC | New | HILL ROM HLDGS INC | $20,000 | – | 590 | – | 0.00% | – |
| WCG | New | WELLCARE HEALTH PLANS INC | $21,000 | – | 385 | – | 0.00% | – |
| V107SC | New | WELLPOINT INC | $21,000 | – | 255 | – | 0.00% | – |
| CI | New | CIGNA CORPORATION | $21,000 | – | 290 | – | 0.00% | – |
| DGX | New | QUEST DIAGNOSTICS INC | $20,000 | – | 325 | – | 0.00% | – |
| OCR | New | OMNICARE INC | $20,000 | – | 425 | – | 0.00% | – |
| HNGR | New | HANGER INC | $20,000 | – | 630 | – | 0.00% | – |
| HLS | New | HEALTHSOUTH CORP | $20,000 | – | 695 | – | 0.00% | – |
| HMA | New | HEALTH MGMT ASSOC INC NEWcl a | $20,000 | – | 1,265 | – | 0.00% | – |
| MOH | New | MOLINA HEALTHCARE INC | $20,000 | – | 550 | – | 0.00% | – |
| MD | New | MEDNAX INC | $21,000 | – | 225 | – | 0.00% | – |
| ENDP | New | ENDO HEALTH SOLUTIONS INC | $19,000 | – | 530 | – | 0.00% | – |
| AMSG | New | AMSURG CORP | $20,000 | – | 565 | – | 0.00% | – |
| MDAS | New | MEDASSETS INC | $20,000 | – | 1,150 | – | 0.00% | – |
| MGLN | New | MAGELLAN HEALTH SVCS INC | $20,000 | – | 365 | – | 0.00% | – |
| ALR | New | ALERE INC | $20,000 | – | 800 | – | 0.00% | – |
| CBMXW | New | COMBIMATRIX CORPORATION*w exp 05/01/201 | $1,000 | – | 5,000 | – | 0.00% | – |