Perceptive Advisors Q3 2016 13F Holdings

Perceptive Advisors Q3 2016 holdings
TickerName Value Shares↓ Weighting
SRPT SAREPTA THERAPEUTICS INCReduce  $208,506
190.2%
3,395,236
-9.9%
13.46%
170.3%
NBIX NEUROCRINE BIOSCIENCES...Reduce  $125,398
-1.4%
2,476,272
-11.5%
8.09%
-8.2%
FOLD AMICUS THERAPEUTICS INCReduce  $104,463
25.5%
14,116,644
-7.4%
6.74%
16.9%
TSRO TESARO INCReduce  $68,405
-28.8%
682,415
-40.3%
4.42%
-33.7%
RTRX RETROPHIN INCReduce  $54,752
-6.3%
2,446,482
-25.4%
3.53%
-12.7%
GBT GLOBAL BLOOD THERAPEUT...Add  $53,802
46.9%
2,334,168
5.7%
3.47%
36.8%
VSAR VERSARTIS INCAdd  $49,351
57.4%
4,028,685
42.1%
3.19%
46.6%
NXTM NXSTAGE MEDICAL INCAdd  $41,726
39.2%
1,669,703
20.8%
2.69%
29.6%
XNCR XENCOR INCReduce  $36,643
26.2%
1,496,229
-2.2%
2.36%
17.4%
LJPC LA JOLLA PHARMACEUTICA...Reduce  $31,482
47.6%
1,323,324
-0.7%
2.03%
37.5%
LBIO LION BIOTECHNOLOGIES INCReduce  $29,360
0.4%
3,567,553
-1.2%
1.90%
-6.6%
WVE WAVE LIFE SCIENCES LTDAdd  $22,191
105.2%
683,448
30.8%
1.43%
90.9%
XLRN ACCELERON PHARMA INCReduce  $21,348
4.2%
589,890
-2.2%
1.38%
-3.0%
CLCD COLUCID PHARMACEUTICAL...New  $21,060552,0301.36%
ACRX ACELRX PHARMACEUTICALS...Reduce  $21,040
30.4%
5,408,728
-9.8%
1.36%
21.5%
QTNT QUOTIENT LTDAdd  $20,893
19.9%
2,671,794
18.8%
1.35%
11.7%
DBVT DBV TECHNOLOGIES SA-SP...depository receiptAdd  $20,464
14.8%
563,268
3.0%
1.32%
6.9%
CRBP CORBUS PHARMACEUTICALS...Reduce  $18,339
91.7%
2,701,023
-15.6%
1.18%
78.6%
RGNX REGENXBIO INCAdd  $17,964
104.3%
1,282,286
16.7%
1.16%
90.2%
RDUS RADIUS HEALTH INCNew  $16,957313,5021.10%
FLML FLAMEL TECHNOLOGIES -S...depository receiptNew  $16,9101,363,7111.09%
KDMN KADMON INCNew  $16,2182,209,6571.05%
DXCM DEXCOM INCAdd  $15,678
57.9%
178,849
42.9%
1.01%
47.1%
AERI AERIE PHARMACEUTICALS INCNew  $15,352406,7710.99%
ALDX ALDEYRA THERAPEUTICS INC  $15,174
37.4%
1,940,4580.0%0.98%
28.0%
ARDX ARDELYX INCNew  $13,6801,057,2570.88%
BPMC BLUEPRINT MEDICINES CORPReduce  $13,662
45.3%
460,024
-0.9%
0.88%
35.3%
DEPO DEPOMED INCReduce  $13,370
14.0%
535,000
-10.8%
0.86%
6.2%
ALDR ALDER BIOPHARMACEUTICA...New  $12,822391,2800.83%
FOMX FOAMIX PHARMACEUTICALS...Add  $12,717
151.9%
1,373,284
72.7%
0.82%
134.6%
CYTOMX THERAPEUTICS, INCpreferred stockNew  $11,634742,0210.75%
NERV MINERVA NEUROSCIENCES INC  $11,440
38.2%
810,5370.0%0.74%
28.6%
ZYNE ZYNERBA PHARMACEUTICAL...Add  $11,339
94.9%
868,897
2.3%
0.73%
81.6%
DERM DERMIRA INCReduce  $11,215
-17.0%
331,610
-28.2%
0.72%
-22.7%
ACRS ACLARIS THERAPEUTICS INCNew  $11,012430,0000.71%
CLSD CLEARSIDE BIOMEDICAL INCReduce  $11,013
147.5%
634,801
-0.0%
0.71%
130.8%
EVH EVOLENT HEALTH INC CL...Reduce  $10,544
-37.1%
428,284
-50.9%
0.68%
-41.4%
VBIV VBI VACCINES INCNew  $10,4903,058,4330.68%
MYOK MYOKARDIA INCAdd  $10,374
66.4%
634,894
26.2%
0.67%
55.1%
QURE UNIQURE NVReduce  $10,043
1.5%
1,312,836
-2.2%
0.65%
-5.5%
VRTX VERTEX PHARMACEUTICALS...Reduce  $9,331
-16.6%
107,000
-17.7%
0.60%
-22.3%
ANI PHARMACEUTICALS INCnote 3.000%  $9,279
14.3%
7,500,0000.0%0.60%
6.4%
CDTX CIDARA THERAPEUTICS INCReduce  $8,855
8.3%
773,369
-2.5%
0.57%
0.9%
FPRX FIVE PRIME THERAPEUTIC...Reduce  $8,740
24.8%
166,509
-1.7%
0.56%
16.0%
FWP FORWARD PHARMA A/S-ADRdepository receiptAdd  $8,494
50.1%
404,472
29.9%
0.55%
39.8%
PFNX PFENEX INCReduce  $8,412
4.6%
939,930
-2.2%
0.54%
-2.7%
ABMD ABIOMED INCNew  $8,13863,2900.52%
ABEO ABEONA THERAPEUTICS INCReduce  $8,016
92.7%
1,336,050
-24.2%
0.52%
79.5%
AVXS AVEXIS INCAdd  $7,830
13400.0%
190,000
12441.3%
0.50%
12525.0%
PSDV PSIVIDA CORPReduce  $7,683
1.9%
2,552,431
-4.2%
0.50%
-5.2%
ACHN ACHILLION PHARMACEUTICALSNew  $7,527929,2900.49%
AKBA AKEBIA THERAPEUTICS INCReduce  $7,295
9.1%
809,096
-9.5%
0.47%
1.7%
DVAX DYNAVAX TECH... DVAXputus equity optionNew  $7,18016,0000.46%
NEPT NEPTUNE TECHNOLOGIES A...  $7,155
3.9%
6,750,4440.0%0.46%
-3.1%
AGRX AGILE THERAPEUTICS INCAdd  $7,120
81.9%
1,020,011
98.3%
0.46%
69.7%
AGEN AGENUS INCNew  $6,462900,0000.42%
CSU CAPITAL SENIOR LIVING ...Reduce  $6,305
-39.1%
375,306
-36.0%
0.41%
-43.3%
ARWR ARROWHEAD PHARMACEUTIC...New  $6,228847,4580.40%
CLVS CLOVIS ONCOLOGY INCNew  $6,183171,5000.40%
XENE XENON PHARMACEUTICALS INCAdd  $6,179
142.0%
762,800
76.2%
0.40%
125.4%
SUPN SUPERNUS PHARMACEUTICA...Reduce  $6,048
18.8%
244,550
-2.2%
0.39%
10.5%
HSGX HISTOGENCIS CORPNew  $5,7061,777,7770.37%
ASMB ASSEMBLY BIOSCIENCES INCNew  $5,606777,6690.36%
CASC CASCADIAN THERAPEUTICS...  $5,599
73.9%
3,414,1210.0%0.36%
61.9%
PTI PROTEOSTASIS THERAPEUT...Add  $5,372
77.1%
344,550
37.8%
0.35%
65.2%
ADMA ADMA BIOLOGICS INCNew  $5,327734,7930.34%
ONS ONCOBIOLOGICS INCReduce  $5,308
18.9%
1,248,990
-4.9%
0.34%
11.0%
AMRN AMARIN CORP PLC-ADRdepository receiptNew  $5,1751,622,2800.33%
SELB SELECTA BIOSCIENCES INCReduce  $4,961
-21.2%
348,150
-22.6%
0.32%
-26.6%
NEURODERM LTDReduce  $4,883
11.3%
264,114
-2.2%
0.32%
3.6%
ANTH ANTHERA PHARMACEUTICAL...Reduce  $4,598
-0.3%
1,459,627
-2.2%
0.30%
-7.2%
CLLS CELLECTIS ADRdepository receiptReduce  $4,323
-11.4%
179,506
-2.2%
0.28%
-17.5%
CEMP CEMPRA INCAdd  $4,247
51.5%
175,503
3.2%
0.27%
41.2%
AGTC APPLIED GENETIC TECHNO...Reduce  $4,167
-55.2%
426,048
-35.3%
0.27%
-58.3%
ABEOW ABEONA THERAPEUTICS IN...warrants  $4,093
282.2%
1,259,6360.0%0.26%
256.8%
BGNE BEIGENE LTDdepository receiptNew  $4,069132,0570.26%
MYL MYLAN NVAdd  $3,610
1571.3%
94,711
1794.2%
0.23%
1453.3%
INNL INNOCOLL HOLDINGS PLCReduce  $3,221
14.7%
547,792
-2.2%
0.21%
6.7%
AVEO AVEO PHARMACEUTICALS INC  $2,766
-7.4%
3,108,8080.0%0.18%
-13.5%
OPHT OPHTHOTECH C... OPHTcallus equity optionNew  $2,740600,0000.18%
APVO APTEVO THERAPEUTICS INCNew  $2,530988,1330.16%
PRTO PROTEON THERAPEUTICS INCReduce  $2,510
13.7%
269,005
-2.2%
0.16%
5.9%
MGCD MGC DIAGNOSTICS CORPReduce  $2,275
3.7%
329,733
-1.9%
0.15%
-3.3%
NEOS NEOS THERAPEUTICS INCReduce  $2,175
-52.8%
330,593
-47.3%
0.14%
-56.2%
RXDX IGNYTA INCReduce  $2,137
-9.4%
339,727
-21.9%
0.14%
-15.9%
ACAD ACADIA PHARMACEUTICALS...New  $2,07565,2400.13%
AFMD AFFIMED NV  $2,041
12.1%
734,3010.0%0.13%
4.8%
ARNI ARNO THERAPEUTICS INCNew  $1,9634,177,5770.13%
ABT ABBOTT LABORATORIESNew  $1,94646,0190.13%
EIGR EIGER BIOPHARMACEUTICA...Add  $1,739
-16.4%
129,920
23.8%
0.11%
-22.2%
CBPO CHINA BIOLOGIC PRODUCT...Reduce  $1,705
14.6%
13,695
-2.2%
0.11%
6.8%
BIO BIO RAD LABORATORIES ...New  $1,63810,0000.11%
MDGN MEDGENICS INCReduce  $1,635
-1.8%
293,460
-2.2%
0.11%
-7.8%
VCRA VOCERA COMMUNICATIONS INCNew  $1,59394,2360.10%
VCEL VERICEL CORPReduce  $1,526
21.7%
544,996
-2.2%
0.10%
13.8%
ALQA ALLIQUA BIOMEDICAL INCNew  $1,5371,921,9510.10%
NVRO NEVRO CORPReduce  $1,226
-95.4%
11,746
-96.8%
0.08%
-95.8%
NVLS NIVALIS THERAPEUTICS INCReduce  $994
72.9%
122,275
-2.2%
0.06%
60.0%
BCLI BRAINSTORM CELL THERAP...New  $964400,0000.06%
ATRS ANTARES PHARMA INCNew  $91200.06%
ONSIZ ONCOBIOLOGICS INC*w exp 2/18/2017Add  $787
289.6%
656,382
41.9%
0.05%
264.3%
ANIP ANI PHARMACEUTICALS INCReduce  $767
-79.5%
11,561
-82.8%
0.05%
-80.8%
LCI LANNETT COMPANY INC  $709
11.8%
26,6700.0%0.05%
4.5%
SCYX SCYNEXIS INCReduce  $662
74.2%
171,185
-2.2%
0.04%
65.4%
AGLE AEGLEA BIOTHERAPEUTICS...Reduce  $664
28.9%
103,585
-2.2%
0.04%
19.4%
PAHC PHIBRO ANIMAL HEALTH ...  $660
45.7%
24,3000.0%0.04%
38.7%
CSBR CHAMPIONS ONCOLOGY INC  $625
-22.0%
372,5970.0%0.04%
-28.6%
BIIB BIOGEN INCNew  $6011,9210.04%
HRC HILL ROM HOLDINGS INCNew  $5939,5630.04%
IMDZ IMMUNE DESIGN CORPNew  $58977,7250.04%
WCG WELLCARE HEALTHCARE PL...  $592
9.2%
5,0560.0%0.04%0.0%
HWAY HEALTHWAYS INCNew  $57221,6080.04%
UTHR UNITED THERAPEUTICS INC  $561
11.5%
4,7530.0%0.04%
2.9%
WOOF VCA INC  $556
3.5%
7,9400.0%0.04%
-2.7%
INCR INC RESEARCH HOLDINGS ...New  $56312,6360.04%
LH LABORATORY CORPORATION...  $549
5.6%
3,9900.0%0.04%
-2.8%
ABC AMERISOURCEBERGEN CORP  $525
1.7%
6,5000.0%0.03%
-5.6%
HUM HUMANA INC ... HUMcallus equity optionNew  $5264000.03%
INCY INCYTE CORPNew  $5305,6190.03%
VWR VWR CORP  $529
-1.9%
18,6570.0%0.03%
-8.1%
ICLR ICON INCNew  $5326,8730.03%
PZRXQ PHASERX INC  $514
-39.7%
200,0000.0%0.03%
-44.1%
MOH MOLINA HEALTHCARE INCReduce  $518
12.9%
8,879
-3.5%
0.03%
3.1%
AET AETNA INC  $514
-5.5%
4,4540.0%0.03%
-13.2%
SCMP SUCAMPO PHARMACEUTICAL...  $506
12.2%
41,0960.0%0.03%
6.5%
A AGILENT TECHNOLOGIES INCNew  $49610,5400.03%
SGYPQ SYNERGY PHARMACEUTICAL...New  $49189,1270.03%
PBYI PUMA BIOTECHNOLOGY INCNew  $4927,3440.03%
MCK MCKESSON CORP  $497
-10.6%
2,9790.0%0.03%
-17.9%
CAH CARDINAL HEALTH INC  $497
-0.4%
6,3980.0%0.03%
-8.6%
UHS UNIVERSAL HEALTH SERVI...  $492
-8.0%
3,9890.0%0.03%
-13.5%
AMAG AMAG PHARMACEUTICALS INCNew  $47919,5240.03%
HCA HCA HOLDINGS INC  $469
-1.9%
6,2020.0%0.03%
-9.1%
MGLN MAGELLAN HEALTH INC  $471
-18.4%
8,7720.0%0.03%
-25.0%
LNTH LANTHEUS HOLDINGS INCNew  $44553,7630.03%
AMSG AMSURG CORPNew  $4446,6180.03%
UNH UNITEDHEALTH GROUP INC  $452
-0.9%
3,2310.0%0.03%
-9.4%
CRL CHARLES RIVER LABORATO...  $457
1.1%
5,4820.0%0.03%
-6.5%
AFAM ALMOST FAMILY INCNew  $43911,9420.03%
KND KINDRED HEATHCARE INC  $432
-9.6%
42,3010.0%0.03%
-15.2%
AMN AMN HEALTHCARE INCNew  $42813,4450.03%
ACST ACASTI PHARMA INC  $414
23.2%
236,5590.0%0.03%
17.4%
ANTM ANTHEM INCNew  $4263,4000.03%
Q QUINTILES IMS HOLDINGS...New  $4145,1030.03%
FCAU FIAT CHRYSLER AUTOMOBI...  $397
4.7%
62,0000.0%0.03%0.0%
THC TENET HEALTHCARE CORP  $367
-18.1%
16,2000.0%0.02%
-22.6%
ENZ ENZO BIOCHEM INC  $342
-14.7%
67,1130.0%0.02%
-21.4%
RACE FERRARI NV  $322
26.8%
6,2000.0%0.02%
16.7%
MACK MERRIMACK PHARMACEUTIC...Reduce  $311
15.2%
48,910
-2.2%
0.02%
5.3%
ONSIW ONCOBIOLOGICS INC*w exp 2/18/2017Add  $313
47.6%
656,382
41.9%
0.02%
33.3%
MNKKQ MALLINCKRODT PLCNew  $3144,5000.02%
ACHI ACCRETIVE HEALTH INCNew  $305125,0000.02%
PERNIX THERAPEUTICS H...dbcv 4.25% 4/01/2021  $292
46.0%
1,000,0000.0%0.02%
35.7%
TDOC TELADOC INCNew  $27515,0000.02%
GNVC GENVEC INCReduce  $259
-92.5%
561,320
-7.5%
0.02%
-92.9%
BVX BOVIE MEDICAL CORPNew  $25348,5440.02%
NTLA INTELLIA THERAPEUTICS INCReduce  $250
-21.9%
14,673
-2.2%
0.02%
-27.3%
LLY ELI LILLY & ... LLYcallus equity optionNew  $2501,0000.02%
PMD PSYCHEMEDICS CORPNew  $25012,6260.02%
ZGNX ZOGENIX INCNew  $21218,5410.01%
NSTG NANOSTRING TECHNOLOGIE...New  $21010,5180.01%
GKOS GLAUKOS CORPAdd  $200
2122.2%
5,300
1666.7%
0.01%
1200.0%
CGNT COGENTIX MEDICAL INCReduce  $180
-63.9%
99,008
-80.9%
0.01%
-65.7%
AMRI ALBANY MOLECULAR RESEARCHNew  $17010,3000.01%
MTD METTLER TOLEDO INTERNA...New  $1744150.01%
NUVA NUVASIVE INCNew  $1732,5890.01%
ARAY ACCURAY INCNew  $17427,3000.01%
LHCG LHC GROUP INCNew  $1754,7450.01%
MDSO MEDIDATA SOLUTIONS INCNew  $1602,8650.01%
BOLD AUDENTES THERAPEUTICS INCNew  $1347,5000.01%
IVC INVACARE CORPNew  $14713,2000.01%
ISRG INTUITIVE SURGICAL INCNew  $1452000.01%
DRAD DIGIRAD CORP  $127
-1.6%
24,9880.0%0.01%
-11.1%
ATRC ATRICURE INCNew  $1267,9490.01%
HNGR HANGER INCNew  $12815,0380.01%
ACETQ ACETO CORPNew  $1156,0540.01%
STML STEMLINE THERAPEUTICS INCReduce  $116
-78.2%
10,702
-86.4%
0.01%
-81.1%
CYNO CYNOSURE INC CLASS ANew  $921,8000.01%
BMRN BIOMARIN PHARMACEUTICA...New  $232500.00%
IMMU IMMUNOMEDICS INCReduce  $17
-96.7%
5,343
-97.6%
0.00%
-97.2%
PPHM PEREGRINE PHARMACEUTICALSReduce  $10
-87.7%
24,332
-89.2%
0.00%
-83.3%
DSCI DERMA SCIENCES INCReduce  $14
-99.2%
2,970
-99.3%
0.00%
-99.2%
CAPR CAPRICOR THERAPEUTICS INC  $13
-18.8%
4,0000.0%0.00%0.0%
SEVION THERAPEUTICS INC  $10
-16.7%
59,2200.0%0.00%0.0%
VYGR VOYAGER THERAPEUTICS INCSold out  $0-6500.00%
AVGR AVINGER INCNew  $51,0620.00%
TNGNQ TENGION INC  $10.0%1,826,3990.0%0.00%
SGMO SANGAMO BIOSCIENCES INCNew  $12720.00%
CRY CRYOLIFE INCNew  $21230.00%
INGN INOGEN INC  $7
16.7%
1250.0%0.00%
EGRX EAGLE PHARMACEUTICALS INCAdd  $3
-100.0%
544,770
81.6%
0.00%
-100.0%
FLKS FLEX PHARMA INC  $3
50.0%
2370.0%0.00%
MD MEDNAX INCNew  $2290.00%
NPCUF ALLON THERAPEUTICS INC  $0751,1240.0%0.00%
ZIOP ZIOPHARM ONCOLOGY INCSold out  $0-1,0000.00%
AVINGER INCSold out  $0-1,062-0.00%
BTX BIOTIME INCSold out  $0-13,740-0.00%
DVAX DYNAVAX TECHNOLOGIES CORPSold out  $0-2,499-0.00%
MCRB SERES THERAPEUTICS INCSold out  $0-1,540-0.00%
JUNO JUNO THERAPEUTICS INCSold out  $0-1,113-0.00%
CORT CORCEPT THERAPEUTICS INCSold out  $0-11,000-0.00%
ATARA BIOTHERAPEUTICS INCSold out  $0-2,500-0.00%
ABBV ABBVIE INCSold out  $0-1,250-0.01%
DPLO DIPLOMAT PHARMACY INCSold out  $0-2,175-0.01%
IMGN IMMUNOGEN INCSold out  $0-25,745-0.01%
HLF HERBALIFE LTDSold out  $0-1,250-0.01%
AIMT AIMMUNE THERAPEUTICS INCSold out  $0-6,448-0.01%
GNCA GENOCEA BIOSCIENCES INCSold out  $0-17,313-0.01%
ZLTQ ZELTIQ AESTHETICS INCSold out  $0-2,638-0.01%
ABBOTT LABSSold out  $0-3,040-0.01%
NVAX NOVAVAX INCSold out  $0-32,000-0.02%
CLDX CELLDEX THERAPEUTICS I...Sold out  $0-71,124-0.02%
CNC CENTENE CORP DELSold out  $0-4,948-0.02%
OPHT OPHTHOTECH CORPSold out  $0-8,145-0.03%
ANTHEM INCSold out  $0-3,400-0.03%
ALMOST FAMILY INCSold out  $0-11,942-0.04%
AMN HEALTHCARE SERVICE...Sold out  $0-13,445-0.04%
LXRX Lexicon Pharmaceutical...Sold out  $0-50,000-0.05%
LPCN LIPOCINE INC LPCNputSold out  $0-284,400-0.06%
LPCN LIPOCINE INC LPCNcallSold out  $0-300,000-0.06%
BCLI BRAINSTROM CELL THERAP...Sold out  $0-400,000-0.07%
ARNO THERAPEUTIC INCSold out  $0-3,463,292-0.08%
GMED GLOBUS MED INCcl aSold out  $0-50,000-0.08%
ABIOMED INCSold out  $0-14,700-0.11%
PETX ARATANA THERAPEUTICS INCSold out  $0-256,500-0.11%
RLYP RELYPSA INC RLYPputSold out  $0-100,000-0.13%
PGNX PROGENICS PH... PGNXputSold out  $0-500,000-0.15%
ALLIQUA BIOMEDICAL INCSold out  $0-1,921,951-0.15%
IONS Ionis Pharma... IONSputSold out  $0-100,000-0.16%
ADMA BIOLOGICS INCSold out  $0-398,394-0.16%
ARDELYX INCSold out  $0-315,955-0.19%
TKAI TOKAI PHARMACEUTICALS INCSold out  $0-661,041-0.25%
TSRO TESARO INC TSROputSold out  $0-50,000-0.29%
ASSEMBLY BIOSCIENCES INCSold out  $0-795,000-0.31%
ADHD ALCOBRA LTDSold out  $0-1,028,272-0.32%
ACADIA PHARMACEUTICALS...Sold out  $0-165,240-0.37%
AXGT AXOVANT SCIENCES LTDSold out  $0-485,000-0.43%
CTMX CYTOMX THERAPEUTICS INCSold out  $0-742,021-0.52%
TEVA TEVA PHARMACEUTICAL IN...adrSold out  $0-196,000-0.68%
ALDER BIOPHARMACEUTICA...Sold out  $0-400,000-0.69%
HEDJ WISDOMTREE E... HEDJputeurope hedged eqSold out  $0-200,000-0.70%
VBIV VBI VACCINES INCSold out  $0-3,058,433-0.84%
STJ ST JUDE MEDICALSold out  $0-233,000-1.26%
SRPT Sarepta Ther... SRPTcallSold out  $0-979,200-1.30%
CPXX CELATOR PHARMACEUTICAL...Sold out  $0-838,400-1.75%
XBI STREETTRACKS... XBIputs&p biotechSold out  $0-500,000-1.88%
MDVN MEDIVATION INCSold out  $0-760,000-3.18%
SRPT Sarepta Ther... SRPTputSold out  $0-7,619,300-10.07%
  • Perceptive Advisors Q3 2016 Portfolio
  • Quarter
    Q3 2016
  • Total value
    $1.23 Billion
  • Holdings
    196
  • Turnover
    76.2%
  • EDGAR